Blood product transfusion and lung transplant outcomes: A systematic review.

The perioperative transfusion of blood products has long been linked to development of acute lung injury and associated with mortality across both medical and surgical patient populations.1,2 The need for blood product transfusion during and after lung transplantation is common and, in many instances, unavoidable. However, this practice may potentially be modifiable.3 In this systematic review, we explore and summarize what is known regarding the impact of blood product transfusion on outcomes following lung transplantation, highlighting the most recent work in this area. Overall, the majority of the literature consists of single center retrospective analyses or the work of multicenter working groups referencing the same database. In the end, there are a number of remaining questions regarding blood product transfusion and their downstream effects on graft function and survival.

Duke Scholars

Author Jacob A Klapper Surgery, Cardiovascular and Thoracic Surgery

Author Leila Ledbetter  

Author Jessica Lynne Poisson Pathology

Author Matthew Hartwig Surgery, Cardiovascular and Thoracic Surgery

Author Nazish Khalid Hashmi Anesthesiology, Cardiothoracic

Author Ian James Welsby Anesthesiology, Cardiothoracic

Author Brandi Anne Bottiger Anesthesiology, Cardiothoracic