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Adam I Perlman

Adjunct Associate Professor in the Department of Medicine
Medicine, General Internal Medicine

Selected Publications


Acupuncture in Sports Medicine.

Journal Article J Acupunct Meridian Stud · December 31, 2023 Acupuncture is gaining popularity and wider acceptance as a treatment modality within the field of sports medicine. Our objective was to provide a comprehensive review of the existing literature pertaining to acupuncture in sports medicine to shed light on ... Full text Link to item Cite

Artificial intelligence for patient scheduling in the real-world health care setting: A metanarrative review

Journal Article Health Policy and Technology · December 1, 2023 Objectives: The application of artificial intelligence (AI) and machine learning (ML) to scheduling in medical practices has considerable implications for most specialties. However, the landscape of AI and ML use in scheduling optimization is unclear. We a ... Full text Cite

Mast cell activation: beyond histamine and tryptase.

Journal Article Expert Rev Clin Immunol · June 2023 INTRODUCTION: Mast cells are found in all tissues and express numerous surface receptors allowing them to sense and respond to allergic, autoimmune, environmental, neurohormonal, pathogenic and stress triggers. Stimulated mast cells are typically called 'a ... Full text Link to item Cite

Nutrition and Emotional Health Education: The Use of Emotional Intelligence and a Plant-Based Diet to Reduce Cardiometabolic Risk

Journal Article Global Advances in Integrative Medicine and Health · January 1, 2023 Background: For individuals living with chronic conditions like diabetes mellitus and obesity, there is a need for sustainable behavioral strategies and physiologic tools. These tools support identifying and addressing barriers to healthy eating, reducing ... Full text Cite

A retrospective analysis of the prevalence and impact of associated comorbidities on fibromyalgia outcomes in a tertiary care center

Journal Article Frontiers in Medicine · January 1, 2023 Background: This retrospective study was designed to analyze the prevalence and impact of associated comorbidities on fibromyalgia (FM) outcomes (functionality, pain, depression levels) for patients who participated in an intensive multicomponent clinical ... Full text Cite

Medical Marijuana Use for Cancer-Related Symptoms among Floridians: A Descriptive Study.

Journal Article J Palliat Med · October 2022 Background: Thirty-six states, including Florida, have legalized marijuana for medical and/or recreational use, yet how it is used and perceived by persons with cancer is not well understood. Objectives: The purpose of this study was to identify patterns o ... Full text Link to item Cite

Increased hope levels correlate with life satisfaction in cancer patients: A systematic review

Journal Article Advances in Integrative Medicine · September 1, 2022 Introduction: Hope is an integral and essential part of the cancer journey. Its association with satisfaction has been described in previous studies. Measures to increase cancer patients’ levels of hope may contribute to the perception of an improvement in ... Full text Cite

The Impact of Optimism on Cancer-Related and Postsurgical Cancer Pain: A Systematic Review.

Journal Article J Pain Symptom Manage · February 2022 BACKGROUND: The impact of psychological factors on pain levels continues to be of interest throughout a cancer patient's journey. The relationship between pain and optimism has been described previously in patients with various diseases. OBJECTIVES: We fur ... Full text Link to item Cite

A Systematic Review of Nutritional Lab Correlates with Chemotherapy Induced Peripheral Neuropathy

Journal Article Journal of Clinical Medicine · January 1, 2022 Chemotherapy induced peripheral neuropathy (CIPN) is a dose-limiting side effect of chemotherapy for which no prevention or cure exists. Cancer and cancer treatments can adversely affect nutritional status. Nutrition may play a role in development of CIPN, ... Full text Cite

Depression: A Modifiable Risk Factor for Poor Outcomes in Fibromyalgia.

Journal Article J Prim Care Community Health · 2022 BACKGROUND: About 4 out of 10 fibromyalgia patients suffer from depression. The European Alliance of Associations for Rheumatology (EULAR) guidelines recommend using antidepressants to treat fibromyalgia. OBJECTIVE: To determine predictors of improved outc ... Full text Link to item Cite

Medical Cannabis State and Federal Regulations: Implications for United States Health Care Entities.

Journal Article Mayo Clin Proc · October 2021 Thirty-six states and four territories in the United States have legalized cannabis for medical and/or recreational use. Marijuana, however, continues to be classified as a schedule I substance under the Federal Controlled Substance Act and remains illegal ... Full text Link to item Cite

Minimally disruptive medicine (MDM) in clinical practice: a qualitative case study of the human immunodeficiency virus (HIV) clinic care model.

Journal Article BMC Health Serv Res · January 6, 2021 BACKGROUND: Recent evidence suggests the need to reframe healthcare delivery for patients with chronic conditions, with emphasis on minimizing healthcare footprint/workload on patients, caregivers, clinicians and health systems through the proposed Minimal ... Full text Link to item Cite

Bridging Intention and Action for Employee Well-Being Using the Intentional Action (InAct) Process: Workshop-Lecture Series

Journal Article Global Advances In Health and Medicine · January 1, 2021 Background: Employee wellness programs can help manage stress and alleviate burnout. Objective: To pilot and disseminate the Intentional Action(InAct) concept for employee wellbeing. Methods: Five independent interactive workshop-lectures with an automated ... Full text Cite

Current trends in health coaching for chronic conditions: A systematic review and meta-analysis of randomized controlled trials.

Journal Article Medicine (Baltimore) · July 24, 2020 BACKGROUND: Chronic conditions are placing a serious burden on individuals as well as the health care system. Health coaching (HC) has emerged as a promising approach that can support effective lifestyle interventions for chronic conditions. However, until ... Full text Link to item Cite

Health and Wellness Coaching in Serving the Needs of Today’s Patients: A Primer for Healthcare Professionals

Journal Article Global Advances In Health and Medicine · January 1, 2020 The past six decades have been marked by leaps and bounds in medical advances, while concurrently clinical outcomes and the quality of life continued to lag or decline. There is a need for more comprehensive approaches to delivering healthcare to patients ... Full text Cite

Efficacy and Safety of Massage for Osteoarthritis of the Knee: a Randomized Clinical Trial.

Journal Article J Gen Intern Med · March 2019 BACKGROUND: Current treatment options for knee osteoarthritis have limited effectiveness and potentially adverse side effects. Massage may offer a safe and effective complement to the management of knee osteoarthritis. OBJECTIVE: Examine effects of whole-b ... Full text Link to item Cite

Adam Perlman, MD, MPH: Transformation in health care lies in finding potential

Journal Article Integrative Medicine (Boulder) · January 1, 2019 Cite

Acupuncture in Sports Medicine.

Journal Article J Acupunct Meridian Stud · December 31, 2023 Acupuncture is gaining popularity and wider acceptance as a treatment modality within the field of sports medicine. Our objective was to provide a comprehensive review of the existing literature pertaining to acupuncture in sports medicine to shed light on ... Full text Link to item Cite

Artificial intelligence for patient scheduling in the real-world health care setting: A metanarrative review

Journal Article Health Policy and Technology · December 1, 2023 Objectives: The application of artificial intelligence (AI) and machine learning (ML) to scheduling in medical practices has considerable implications for most specialties. However, the landscape of AI and ML use in scheduling optimization is unclear. We a ... Full text Cite

Mast cell activation: beyond histamine and tryptase.

Journal Article Expert Rev Clin Immunol · June 2023 INTRODUCTION: Mast cells are found in all tissues and express numerous surface receptors allowing them to sense and respond to allergic, autoimmune, environmental, neurohormonal, pathogenic and stress triggers. Stimulated mast cells are typically called 'a ... Full text Link to item Cite

Nutrition and Emotional Health Education: The Use of Emotional Intelligence and a Plant-Based Diet to Reduce Cardiometabolic Risk

Journal Article Global Advances in Integrative Medicine and Health · January 1, 2023 Background: For individuals living with chronic conditions like diabetes mellitus and obesity, there is a need for sustainable behavioral strategies and physiologic tools. These tools support identifying and addressing barriers to healthy eating, reducing ... Full text Cite

A retrospective analysis of the prevalence and impact of associated comorbidities on fibromyalgia outcomes in a tertiary care center

Journal Article Frontiers in Medicine · January 1, 2023 Background: This retrospective study was designed to analyze the prevalence and impact of associated comorbidities on fibromyalgia (FM) outcomes (functionality, pain, depression levels) for patients who participated in an intensive multicomponent clinical ... Full text Cite

Medical Marijuana Use for Cancer-Related Symptoms among Floridians: A Descriptive Study.

Journal Article J Palliat Med · October 2022 Background: Thirty-six states, including Florida, have legalized marijuana for medical and/or recreational use, yet how it is used and perceived by persons with cancer is not well understood. Objectives: The purpose of this study was to identify patterns o ... Full text Link to item Cite

Increased hope levels correlate with life satisfaction in cancer patients: A systematic review

Journal Article Advances in Integrative Medicine · September 1, 2022 Introduction: Hope is an integral and essential part of the cancer journey. Its association with satisfaction has been described in previous studies. Measures to increase cancer patients’ levels of hope may contribute to the perception of an improvement in ... Full text Cite

The Impact of Optimism on Cancer-Related and Postsurgical Cancer Pain: A Systematic Review.

Journal Article J Pain Symptom Manage · February 2022 BACKGROUND: The impact of psychological factors on pain levels continues to be of interest throughout a cancer patient's journey. The relationship between pain and optimism has been described previously in patients with various diseases. OBJECTIVES: We fur ... Full text Link to item Cite

A Systematic Review of Nutritional Lab Correlates with Chemotherapy Induced Peripheral Neuropathy

Journal Article Journal of Clinical Medicine · January 1, 2022 Chemotherapy induced peripheral neuropathy (CIPN) is a dose-limiting side effect of chemotherapy for which no prevention or cure exists. Cancer and cancer treatments can adversely affect nutritional status. Nutrition may play a role in development of CIPN, ... Full text Cite

Depression: A Modifiable Risk Factor for Poor Outcomes in Fibromyalgia.

Journal Article J Prim Care Community Health · 2022 BACKGROUND: About 4 out of 10 fibromyalgia patients suffer from depression. The European Alliance of Associations for Rheumatology (EULAR) guidelines recommend using antidepressants to treat fibromyalgia. OBJECTIVE: To determine predictors of improved outc ... Full text Link to item Cite

Medical Cannabis State and Federal Regulations: Implications for United States Health Care Entities.

Journal Article Mayo Clin Proc · October 2021 Thirty-six states and four territories in the United States have legalized cannabis for medical and/or recreational use. Marijuana, however, continues to be classified as a schedule I substance under the Federal Controlled Substance Act and remains illegal ... Full text Link to item Cite

Minimally disruptive medicine (MDM) in clinical practice: a qualitative case study of the human immunodeficiency virus (HIV) clinic care model.

Journal Article BMC Health Serv Res · January 6, 2021 BACKGROUND: Recent evidence suggests the need to reframe healthcare delivery for patients with chronic conditions, with emphasis on minimizing healthcare footprint/workload on patients, caregivers, clinicians and health systems through the proposed Minimal ... Full text Link to item Cite

Bridging Intention and Action for Employee Well-Being Using the Intentional Action (InAct) Process: Workshop-Lecture Series

Journal Article Global Advances In Health and Medicine · January 1, 2021 Background: Employee wellness programs can help manage stress and alleviate burnout. Objective: To pilot and disseminate the Intentional Action(InAct) concept for employee wellbeing. Methods: Five independent interactive workshop-lectures with an automated ... Full text Cite

Current trends in health coaching for chronic conditions: A systematic review and meta-analysis of randomized controlled trials.

Journal Article Medicine (Baltimore) · July 24, 2020 BACKGROUND: Chronic conditions are placing a serious burden on individuals as well as the health care system. Health coaching (HC) has emerged as a promising approach that can support effective lifestyle interventions for chronic conditions. However, until ... Full text Link to item Cite

Health and Wellness Coaching in Serving the Needs of Today’s Patients: A Primer for Healthcare Professionals

Journal Article Global Advances In Health and Medicine · January 1, 2020 The past six decades have been marked by leaps and bounds in medical advances, while concurrently clinical outcomes and the quality of life continued to lag or decline. There is a need for more comprehensive approaches to delivering healthcare to patients ... Full text Cite

Efficacy and Safety of Massage for Osteoarthritis of the Knee: a Randomized Clinical Trial.

Journal Article J Gen Intern Med · March 2019 BACKGROUND: Current treatment options for knee osteoarthritis have limited effectiveness and potentially adverse side effects. Massage may offer a safe and effective complement to the management of knee osteoarthritis. OBJECTIVE: Examine effects of whole-b ... Full text Link to item Cite

Adam Perlman, MD, MPH: Transformation in health care lies in finding potential

Journal Article Integrative Medicine (Boulder) · January 1, 2019 Cite

Osteoarthritis

Chapter · January 1, 2018 Full text Cite

Improvements in Resilience, Stress, and Somatic Symptoms Following Online Resilience Training: A Dose-Response Effect.

Journal Article J Occup Environ Med · January 2018 OBJECTIVE: To determine if participation in an online resilience program impacts resilience, stress, and somatic symptoms. METHODS: Approximately 600 enrollees in the meQuilibrium resilience program received a series of brief, individually prescribed video ... Full text Link to item Cite

Massage Therapy and Quality of Life in Osteoarthritis of the Knee: A Qualitative Study.

Journal Article Pain Med · June 1, 2017 OBJECTIVE: We hypothesized that participants receiving Swedish massage would experience benefits such as stress reduction and enhanced quality of life, in addition to the osteoarthritis-specific effects assessed in a randomized controlled clinical trial. D ... Full text Link to item Cite

Integrative health care services utilization as a function of body mass index: A BraveNet practice-based research network study

Journal Article Advances in Integrative Medicine · April 1, 2017 Background Obesity is a significant public health issue with no consensus regarding optimal medical management. Integrative medicine (IM) may help to fill this gap. Objectives (1) To characterize the sociodemographics, psychosocial functioning, health beha ... Full text Cite

The Positive Effect of Resilience on Stress and Business Outcomes in Difficult Work Environments.

Journal Article J Occup Environ Med · February 2017 OBJECTIVE: To examine whether resilience has a protective effect in difficult work environments. METHODS: A survey of 2063 individuals measured individual resilience, stress, burnout, sleep problems, likelihood of depression, job satisfaction, intent to qu ... Full text Link to item Cite

Living and Leading With Resilience.

Journal Article Explore (NY) · 2017 Full text Link to item Cite

Perceptions of massage therapists participating in a randomized controlled trial

Journal Article International Journal of Therapeutic Massage and Bodywork: Research, Education, and Practice · September 1, 2015 Background: Clinical practice and randomized trials often have disparate aims, despite involving similar interventions. Attitudes and expectancies of practitioners influence patient outcomes, and there is growing emphasis on optimizing providerpatient rela ... Full text Cite

Pilot study of massage in veterans with knee osteoarthritis.

Journal Article J Altern Complement Med · June 2015 OBJECTIVES: To (1) assess the feasibility and acceptability of Swedish massage among Department of Veterans Affairs (VA) health care users with knee osteoarthritis (OA) and (2) collect preliminary data on efficacy of Swedish massage in this patient group. ... Full text Link to item Cite

Integrative Medicine Patients Have High Stress, Pain, and Psychological Symptoms.

Journal Article Explore (NY) · 2015 CONTEXT: Integrative medicine (IM) is a rapidly growing field whose providers report clinical success in treating significant stress, chronic pain, and depressive and anxiety symptoms. While IM therapies have demonstrated efficacy for numerous medical cond ... Full text Link to item Cite

Psychosocial benefits of cardiac rehabilitation among women compared with men.

Journal Article J Cardiopulm Rehabil Prev · 2014 PURPOSE: Cardiac rehabilitation (CR) has been shown to reduce cardiac risk and improve the psychosocial functioning of participants. This study examines gender differences on several psychosocial indicators across the course of CR. METHODS: Patients (N = 3 ... Full text Link to item Cite

Integrative Health Coach Training: A Model for Shifting the Paradigm Toward Patient-centricity and Meeting New National Prevention Goals.

Journal Article Glob Adv Health Med · May 2013 OBJECTIVE: To describe the evolution, training, and results of an emerging allied health profession skilled in eliciting sustainable health-related behavior change and charged with improving patient engagement. METHODS: Through techniques sourced from huma ... Full text Link to item Cite

A point-of-sale communications campaign to provide consumers safety information on drug-dietary supplement interactions: a pilot study.

Journal Article Health Commun · 2013 Concurrent use of dietary supplements with over-the-counter and prescription pharmaceuticals has become increasingly common, and with this trend, so has the incidence of adverse drug-supplement interactions. In the current market, consumers have no way to ... Full text Link to item Cite

Prevalence and correlates of postdiagnosis initiation of complementary and alternative medicine among patients at a comprehensive cancer center.

Journal Article J Oncol Pract · January 2013 PURPOSE: Patients with cancer increasingly use complementary and alternative medicine (CAM) in conjunction with conventional oncology treatments. Previous studies have not investigated postdiagnosis initiation of CAM therapies or independent correlates of ... Full text Link to item Cite

Development of a manualized protocol of massage therapy for clinical trials in osteoarthritis.

Journal Article Trials · October 4, 2012 BACKGROUND: Clinical trial design of manual therapies may be especially challenging as techniques are often individualized and practitioner-dependent. This paper describes our methods in creating a standardized Swedish massage protocol tailored to subjects ... Full text Link to item Cite

Osteoarthritis

Chapter · January 1, 2012 Full text Cite

Evidence and potential mechanisms for mindfulness practices and energy psychology for obesity and binge-eating disorder.

Journal Article Explore (NY) · 2012 Obesity is a growing epidemic. Chronic stress produces endocrine and immune factors that are contributors to obesity's etiology. These biochemicals also can affect appetite and eating behaviors that can lead to binge-eating disorder. The inadequacies of st ... Full text Link to item Cite

Massage therapy for osteoarthritis of the knee: a randomized dose-finding trial.

Journal Article PLoS One · 2012 BACKGROUND: In a previous trial of massage for osteoarthritis (OA) of the knee, we demonstrated feasibility, safety and possible efficacy, with benefits that persisted at least 8 weeks beyond treatment termination. METHODS: We performed a RCT to identify t ... Full text Link to item Cite

Perspectives about complementary and alternative medicine in rheumatology.

Journal Article Rheum Dis Clin North Am · February 2011 Complementary and alternative medical (CAM) treatments are considered nonmainstream therapies. The popularity and widespread usage of CAM reflects the inadequacies of the current understanding and management of rheumatic and musculoskeletal (and other) dis ... Full text Link to item Cite

Multivitamin/Mineral supplementation does not affect standardized assessment of academic performance in elementary school children.

Journal Article J Am Diet Assoc · July 2010 Limited research suggests that micronutrient supplementation may have a positive effect on the academic performance and behavior of school-aged children. To determine the effect of multivitamin/mineral supplementation on academic performance, students in g ... Full text Link to item Cite

Developing a complementary, alternative, and integrative medicine course: one medical school's experience.

Journal Article J Altern Complement Med · May 2010 BACKGROUND: There is significant overlap with many concepts emphasized in integrative medicine and current educational priorities within medical school education such as cultural sensitivity, doctor-patient relationship, and physician self-care. Although t ... Full text Link to item Cite

Intravenous micronutrient therapy (Myers' Cocktail) for fibromyalgia: a placebo-controlled pilot study.

Journal Article J Altern Complement Med · March 2009 OBJECTIVES: Intravenous micronutrient therapy (IVMT), and specifically the Myers' Cocktail, is a popular approach for treating fibromyalgia syndrome (FMS) among complementary and alternative medicine practitioners, but its efficacy is uncertain. This trial ... Full text Link to item Cite

Effects of external qigong therapy on osteoarthritis of the knee. A randomized controlled trial.

Journal Article Clin Rheumatol · December 2008 The objective of our study was to assess the efficacy of external qigong therapy (EQT), a traditional Chinese medicine practice, in reducing pain and improving functionality of patients with knee osteoarthritis (OA). One hundred twelve adults with knee OA ... Full text Link to item Cite

Evaluation of diet quality and weight status of children from a low socioeconomic urban environment supports "at risk" classification.

Journal Article J Am Diet Assoc · November 2007 This cross-sectional study evaluated diet quality and weight status in 248 randomly selected low-income urban children, aged 7 to 13 years, who were participating in a larger study on the effectiveness of multivitamin supplementation on school performance. ... Full text Link to item Cite

Osteoarthritis

Chapter · January 1, 2007 Full text Cite

Massage therapy for osteoarthritis of the knee: a randomized controlled trial.

Journal Article Arch Intern Med · December 11, 2006 BACKGROUND: Massage therapy is an attractive treatment option for osteoarthritis (OA), but its efficacy is uncertain. We conducted a randomized, controlled trial of massage therapy for OA of the knee. METHODS: Sixty-eight adults with radiographically confi ... Full text Link to item Cite

Evolving approaches to management of osteoarthritis

Journal Article Drug Benefit Trends · June 1, 2004 The goals of osteoarthritis (OA) therapy are to retard the destructive process, preserve joint structures, control pain and swelling, maintain mobility, minimize disability and, ultimately, improve the patient's quality of life. Symptoms are relieved by tr ... Cite

Medical clinics of North America: Preface

Journal Article Medical Clinics of North America · 2002 Full text Cite

Complementary and alternative medicine. The importance of doctor-patient communication.

Journal Article Med Clin North Am · January 2002 The foundation of good medical care is a comfortable and evolving relationship between the patient and the physician. Since the dawn of medicine with Hippocrates and later Plato, this relationship was regarded as the foundation of the art of medicine. This ... Full text Link to item Cite

Talking with patients about alternative and complementary medicine.

Journal Article Rheum Dis Clin North Am · November 1999 The growing use of alternative and complementary therapies in the United States as well as other parts of the world is a trend that the responsible rheumatologist cannot ignore. With chronic musculoskeletal conditions being the leading indication for the u ... Full text Link to item Cite