Scholars@Duke
Amie Kawasaki

Amie Kawasaki

Assistant Professor of Obstetrics and Gynecology
Obstetrics and Gynecology, Urogynecology
amie.kawasaki@duke.edu
3192, Durham, NC 27710
5324 McFarland Drive, Suite 310, Durham, NC 27707
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Selected Publications

Vaginal morphology and position associated with prolapse recurrence after vaginal surgery: A secondary analysis of the DEMAND study.

Journal Article BJOG · February 2024 OBJECTIVE: To identify vaginal morphology and position factors associated with prolapse recurrence following vaginal surgery. DESIGN: Secondary analysis of magnetic resonance images (MRI) of the Defining Mechanisms of Anterior Vaginal Wall Descent cross-se ... Full text Link to item Cite

Successful sacral neuromodulation treatment of refractory faecal incontinence in a patient with spina bifida and partial sacral agenesis.

Journal Article BMJ Case Rep · September 5, 2023 A woman in her early 20s with a history of lumbosacral lipomyelomeningocele with associated partial sacral agenesis and tethered cord was referred for possible sacral neuromodulation treatment of her refractory faecal incontinence. Anorectal testing reveal ... Full text Link to item Cite

Defining mechanisms of recurrence following apical prolapse repair based on imaging criteria.

Journal Article Am J Obstet Gynecol · November 2021 BACKGROUND: Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate of anatomic recurrence and to develop ... Full text Link to item Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Controlling faecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomised clinical trial.

Journal Article Lancet Gastroenterol Hepatol · September 2019 BACKGROUND: Well designed, large comparative effectiveness trials assessing the efficacy of primary interventions for faecal incontinence are few in number. The objectives of this study were to compare different combinations of anorectal manometry-assisted ... Full text Open Access Link to item Cite

The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.

Journal Article J Am Geriatr Soc · April 2019 BACKGROUND/OBJECTIVES: Every year, up to 40% of the more than 16 million older Americans who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD) or delirium. Each of these distinct syndromes is associated with decreased quality of ... Full text Open Access Link to item Cite

Surgical Alteration of Genital Hiatus Size and Anatomic Failure After Vaginal Vault Suspension.

Journal Article Obstet Gynecol · June 2018 OBJECTIVE: To compare anatomic outcomes after native tissue vaginal vault suspension among women categorized by their preoperative and 6-week postoperative genital hiatus size. METHODS: We performed a retrospective cohort study in women who underwent nativ ... Full text Link to item Cite

Robotic-assisted sacrocolpopexy: early postoperative outcomes after surgical reduction of enlarged genital hiatus.

Journal Article Am J Obstet Gynecol · May 2018 BACKGROUND: Currently, the decision to perform a concurrent posterior repair/perineoplasty at the time of robotic-assisted sacrocolpopexy is not standardized. OBJECTIVE: We sought to compare anatomic failure after robotic-assisted sacrocolpopexy among 3 gr ... Full text Link to item Cite

Do Mixed-Flora Preoperative Urine Cultures Matter?

Journal Article South Med J · June 2017 OBJECTIVES: To determine whether mixed-flora preoperative urine cultures, as compared with no-growth preoperative urine cultures, are associated with a higher prevalence of postoperative urinary tract infections (UTIs). METHODS: This was a retrospective co ... Full text Link to item Cite

Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial.

Journal Article Obstet Gynecol · January 2014 Featured Publication OBJECTIVE: To evaluate whether nitrofurantoin prophylaxis prevents postoperative urinary tract infection (UTI) in patients receiving transurethral catheterization after pelvic reconstructive surgery. METHODS: In a randomized, double-blind, placebo-controll ... Full text Link to item Cite

Impact of staged InterStim implantation on the postoperative activities of daily living and pain.

Journal Article Int Urogynecol J · July 2013 Featured Publication OBJECTIVES: To evaluate the short-term effects of staged InterStim implantation on activities of daily living (ADL) and pain. METHODS: This prospective study assessed women undergoing staged InterStim implantation. The Older Americans Resources and Service ... Full text Link to item Cite

Comparing the risk of urethrolysis for the treatment of voiding dysfunction between two retropubic mesh slings: a case-control study.

Journal Article Int Urogynecol J · April 2013 Featured Publication INTRODUCTION AND HYPOTHESIS: Long-term outcome data exist with Gynecare TVT tension-free support for incontinence (TVT), yet few comparisons have been made to newer retropubic sling delivery systems, especially with regards to urethrolysis for postoperativ ... Full text Link to item Cite

Computer modeling informs study design: vaginal estrogen to prevent mesh erosion after different routes of prolapse surgery.

Journal Article Int Urogynecol J · March 2013 Featured Publication INTRODUCTION AND HYPOTHESIS: Many clinicians use perioperative vaginal estrogen therapy (estradiol, E(2)) to diminish the risk of mesh erosion after prolapse surgery, though supporting evidence is limited. We assessed the feasibility of a factorial randomi ... Full text Link to item Cite

Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy.

Journal Article J Reprod Med · 2013 OBJECTIVE: To determine whether obese body mass index is associated with the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy. STUDY DESIGN: We conducted a retrospective cohort study of the risk of recurrent anterior prolapse 6 mont ... Link to item Cite

The efficacy of posterior tibial nerve stimulation for the treatment of overactive bladder in women: a systematic review.

Journal Article Int Urogynecol J · November 2012 Featured Publication INTRODUCTION AND HYPOTHESIS: Posterior tibial nerve stimulation (PTNS) is a percutaneous method of peripheral, sacral neuromodulation. Its current use is limited; however, published data suggest PTNS may be an effective treatment for overactive bladder (OA ... Full text Link to item Cite

Do urodynamic parameters predict persistent postoperative stress incontinence after midurethral sling? A systematic review.

Journal Article Int Urogynecol J · July 2012 Featured Publication INTRODUCTION AND HYPOTHESIS: It is unclear whether preoperative urodynamic study (UDS) values are predictive of outcomes after midurethral sling. MATERIALS AND METHODS: We systematically reviewed multiple databases from January 1989 to October 2011 for Eng ... Full text Link to item Cite

Long-term outcomes after stress urinary incontinence surgery.

Journal Article Obstet Gynecol · July 2012 Featured Publication OBJECTIVES: To compare the long-term risk of repeat stress urinary incontinence (SUI) surgery after different types of initial SUI surgery and to identify predictors of time to repeat SUI surgery in a large, population-based cohort. METHODS: We used de-ide ... Full text Link to item Cite

Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy.

Journal Article The Journal of reproductive medicine · 2012 Featured Publication Cite

Predicting the number of women who will undergo incontinence and prolapse surgery, 2010 to 2050.

Journal Article Am J Obstet Gynecol · September 2011 Featured Publication OBJECTIVE: We sought to estimate the number of women who will undergo inpatient and outpatient surgery for stress urinary incontinence (SUI) or pelvic organ prolapse (POP) in the United States from 2010 through 2050. STUDY DESIGN: Using the 2007 Nationwide ... Full text Link to item Cite

Vaginal morphology and position associated with prolapse recurrence after vaginal surgery: A secondary analysis of the DEMAND study.

Journal Article BJOG · February 2024 OBJECTIVE: To identify vaginal morphology and position factors associated with prolapse recurrence following vaginal surgery. DESIGN: Secondary analysis of magnetic resonance images (MRI) of the Defining Mechanisms of Anterior Vaginal Wall Descent cross-se ... Full text Link to item Cite

Successful sacral neuromodulation treatment of refractory faecal incontinence in a patient with spina bifida and partial sacral agenesis.

Journal Article BMJ Case Rep · September 5, 2023 A woman in her early 20s with a history of lumbosacral lipomyelomeningocele with associated partial sacral agenesis and tethered cord was referred for possible sacral neuromodulation treatment of her refractory faecal incontinence. Anorectal testing reveal ... Full text Link to item Cite

Defining mechanisms of recurrence following apical prolapse repair based on imaging criteria.

Journal Article Am J Obstet Gynecol · November 2021 BACKGROUND: Prolapse recurrence after transvaginal surgical repair is common; however, its mechanisms are ill-defined. A thorough understanding of how and why prolapse repairs fail is needed to address their high rate of anatomic recurrence and to develop ... Full text Link to item Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Controlling faecal incontinence in women by performing anal exercises with biofeedback or loperamide: a randomised clinical trial.

Journal Article Lancet Gastroenterol Hepatol · September 2019 BACKGROUND: Well designed, large comparative effectiveness trials assessing the efficacy of primary interventions for faecal incontinence are few in number. The objectives of this study were to compare different combinations of anorectal manometry-assisted ... Full text Open Access Link to item Cite

The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.

Journal Article J Am Geriatr Soc · April 2019 BACKGROUND/OBJECTIVES: Every year, up to 40% of the more than 16 million older Americans who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD) or delirium. Each of these distinct syndromes is associated with decreased quality of ... Full text Open Access Link to item Cite

Surgical Alteration of Genital Hiatus Size and Anatomic Failure After Vaginal Vault Suspension.

Journal Article Obstet Gynecol · June 2018 OBJECTIVE: To compare anatomic outcomes after native tissue vaginal vault suspension among women categorized by their preoperative and 6-week postoperative genital hiatus size. METHODS: We performed a retrospective cohort study in women who underwent nativ ... Full text Link to item Cite

Robotic-assisted sacrocolpopexy: early postoperative outcomes after surgical reduction of enlarged genital hiatus.

Journal Article Am J Obstet Gynecol · May 2018 BACKGROUND: Currently, the decision to perform a concurrent posterior repair/perineoplasty at the time of robotic-assisted sacrocolpopexy is not standardized. OBJECTIVE: We sought to compare anatomic failure after robotic-assisted sacrocolpopexy among 3 gr ... Full text Link to item Cite

Do Mixed-Flora Preoperative Urine Cultures Matter?

Journal Article South Med J · June 2017 OBJECTIVES: To determine whether mixed-flora preoperative urine cultures, as compared with no-growth preoperative urine cultures, are associated with a higher prevalence of postoperative urinary tract infections (UTIs). METHODS: This was a retrospective co ... Full text Link to item Cite

Oral antibiotics to prevent postoperative urinary tract infection: a randomized controlled trial.

Journal Article Obstet Gynecol · January 2014 Featured Publication OBJECTIVE: To evaluate whether nitrofurantoin prophylaxis prevents postoperative urinary tract infection (UTI) in patients receiving transurethral catheterization after pelvic reconstructive surgery. METHODS: In a randomized, double-blind, placebo-controll ... Full text Link to item Cite

Impact of staged InterStim implantation on the postoperative activities of daily living and pain.

Journal Article Int Urogynecol J · July 2013 Featured Publication OBJECTIVES: To evaluate the short-term effects of staged InterStim implantation on activities of daily living (ADL) and pain. METHODS: This prospective study assessed women undergoing staged InterStim implantation. The Older Americans Resources and Service ... Full text Link to item Cite

Comparing the risk of urethrolysis for the treatment of voiding dysfunction between two retropubic mesh slings: a case-control study.

Journal Article Int Urogynecol J · April 2013 Featured Publication INTRODUCTION AND HYPOTHESIS: Long-term outcome data exist with Gynecare TVT tension-free support for incontinence (TVT), yet few comparisons have been made to newer retropubic sling delivery systems, especially with regards to urethrolysis for postoperativ ... Full text Link to item Cite

Computer modeling informs study design: vaginal estrogen to prevent mesh erosion after different routes of prolapse surgery.

Journal Article Int Urogynecol J · March 2013 Featured Publication INTRODUCTION AND HYPOTHESIS: Many clinicians use perioperative vaginal estrogen therapy (estradiol, E(2)) to diminish the risk of mesh erosion after prolapse surgery, though supporting evidence is limited. We assessed the feasibility of a factorial randomi ... Full text Link to item Cite

Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy.

Journal Article J Reprod Med · 2013 OBJECTIVE: To determine whether obese body mass index is associated with the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy. STUDY DESIGN: We conducted a retrospective cohort study of the risk of recurrent anterior prolapse 6 mont ... Link to item Cite

The efficacy of posterior tibial nerve stimulation for the treatment of overactive bladder in women: a systematic review.

Journal Article Int Urogynecol J · November 2012 Featured Publication INTRODUCTION AND HYPOTHESIS: Posterior tibial nerve stimulation (PTNS) is a percutaneous method of peripheral, sacral neuromodulation. Its current use is limited; however, published data suggest PTNS may be an effective treatment for overactive bladder (OA ... Full text Link to item Cite

Do urodynamic parameters predict persistent postoperative stress incontinence after midurethral sling? A systematic review.

Journal Article Int Urogynecol J · July 2012 Featured Publication INTRODUCTION AND HYPOTHESIS: It is unclear whether preoperative urodynamic study (UDS) values are predictive of outcomes after midurethral sling. MATERIALS AND METHODS: We systematically reviewed multiple databases from January 1989 to October 2011 for Eng ... Full text Link to item Cite

Long-term outcomes after stress urinary incontinence surgery.

Journal Article Obstet Gynecol · July 2012 Featured Publication OBJECTIVES: To compare the long-term risk of repeat stress urinary incontinence (SUI) surgery after different types of initial SUI surgery and to identify predictors of time to repeat SUI surgery in a large, population-based cohort. METHODS: We used de-ide ... Full text Link to item Cite

Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy.

Journal Article The Journal of reproductive medicine · 2012 Featured Publication Cite

Predicting the number of women who will undergo incontinence and prolapse surgery, 2010 to 2050.

Journal Article Am J Obstet Gynecol · September 2011 Featured Publication OBJECTIVE: We sought to estimate the number of women who will undergo inpatient and outpatient surgery for stress urinary incontinence (SUI) or pelvic organ prolapse (POP) in the United States from 2010 through 2050. STUDY DESIGN: Using the 2007 Nationwide ... Full text Link to item Cite

Correlation of maximum urethral closure pressure with Valsalva leak point pressure using air-charged urodynamic catheters.

Journal Article Int Urogynecol J Pelvic Floor Dysfunct · September 2009 Featured Publication INTRODUCTION AND HYPOTHESIS: The objective of this study was to measure the correlation of maximum urethral closure pressure (MUCP) with Valsalva leak point pressure (VLPP) in women with urodynamic stress incontinence using air-charged urodynamic catheters ... Full text Link to item Cite