Scholars@Duke
Andrew Sherwood

Andrew Sherwood

Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
andrew.sherwood@duke.edu
Box 3119 Med Ctr, Durham, NC 27710
4571 Hosp South, Durham, NC 27710

Selected Publications

Use of Impedance Cardiography to Guide Blood Pressure Lowering Medication Selection: Systematic Review of Randomized Controlled Trials.

Journal Article Am J Hypertens · October 14, 2024 BACKGROUND: Blood pressure (BP) control can be difficult to attain due to multiple factors, including choosing and titrating antihypertensive medications. Measurement of hemodynamic parameters using impedance cardiography (ICG) at the point of care may all ... Full text Link to item Cite

Depressive symptoms are associated with clinical outcomes in heart failure with reduced ejection fraction.

Journal Article ESC Heart Fail · October 2024 AIMS: The objective of this study was to examine associations between elevated depressive symptoms and increased risk of adverse clinical events patients with heart failure and reduced ejection fraction (HFrEF), as well as the potential contribution of hea ... Full text Link to item Cite

Cognitive behavior therapy for insomnia for untreated hypertension with comorbid insomnia disorder: The SLEEPRIGHT clinical trial.

Journal Article J Clin Hypertens (Greenwich) · April 2024 Insomnia and poor sleep are associated with an increased risk of developing cardiovascular disease (CVD) and its precursors, including hypertension. In 2022, the American Heart Association (AHA) added inadequate sleep to its list of health behaviors that i ... Full text Link to item Cite

Effects of Lifestyle Modification on Psychosocial Function in Patients With Resistant Hypertension: SECONDARY OUTCOMES FROM THE TRIUMPH RANDOMIZED CLINICAL TRIAL.

Journal Article J Cardiopulm Rehabil Prev · January 1, 2024 PURPOSE: In a secondary analysis of the TRIUMPH clinical trial, psychological outcomes in patients with resistant hypertension (RH) receiving a diet and exercise intervention delivered in a cardiac rehabilitation setting were compared with those receiving ... Full text Link to item Cite

Lifestyle Medicine as a Treatment for Resistant Hypertension.

Journal Article Curr Hypertens Rep · October 2023 PURPOSE OF REVIEW: Approximately 10% of the adults with hypertension fail to achieve the recommended blood pressure treatment targets on 3 antihypertensive medications or require ≥ 4 medications to achieve goal. These patients with 'resistant hypertension ... Full text Link to item Cite

Effect of cognitive processing therapy on markers of cardiovascular risk in posttraumatic stress disorder patients: A randomized clinical trial.

Journal Article J Psychosom Res · July 2023 OBJECTIVE: Posttraumatic stress disorder (PTSD) is associated with elevated risk of coronary heart disease (CHD); however, the effects of PTSD treatment on CHD biomarkers is unknown. This study examined whether cognitive processing therapy (CPT) improves 2 ... Full text Link to item Cite

Nightmares: an independent risk factor for cardiovascular disease?

Conference Sleep · June 13, 2023 STUDY OBJECTIVES: Prior work has established associations between post-traumatic stress disorder (PTSD), disrupted sleep, and cardiovascular disease (CVD), but few studies have examined health correlates of nightmares beyond risks conferred by PTSD. This s ... Full text Link to item Cite

Inflammation moderates the effects of lifestyle modification on neurocognition among individuals with resistant hypertension.

Journal Article J Clin Hypertens (Greenwich) · January 2023 Individuals with resistant hypertension (RH) have the greatest risk of cerebrovascular disease and cognitive impairment among individuals with hypertension. Elevated levels of pro-inflammatory cytokines may represent a critical yet unexamined factor influe ... Full text Link to item Cite

Sleep Quality, Metabolic Function, Physical Activity, and Neurocognition Among Individuals with Resistant Hypertension.

Journal Article J Alzheimers Dis · 2023 BACKGROUND: Resistant hypertension (RH) is a major risk factor for stroke, cognitive decline, and dementia. Sleep quality is increasingly suggested to play an important role linking RH to cognitive outcomes, although the mechanisms linking sleep quality to ... Full text Link to item Cite

Exercise and Escitalopram in the Treatment of Anxiety in Patients with Coronary Heart Disease: One Year Follow-Up of the UNWIND Randomized Clinical Trial.

Journal Article J Cardiovasc Dev Dis · September 22, 2022 Anxiety is common among patients with coronary heart disease (CHD) and is associated with a worse prognosis. UNWIND was a 12-week randomized clinical trial comparing exercise and escitalopram to placebo on measures of anxiety, depression, and CHD biomarker ... Full text Link to item Cite

Longer term benefits of exercise and escitalopram in the treatment of anxiety in patients with coronary heart disease: Six month follow-up of the UNWIND randomized clinical trial.

Journal Article Am Heart J · September 2022 BACKGROUND: Anxiety is a common comorbidity in patients with coronary heart disease (CHD) and is associated with worse prognosis. However, effective treatment for anxiety in CHD patients is uncertain. The UNWIND randomized clinical trial showed that 12-wee ... Full text Link to item Cite

Lifestyle modification and cognitive function among individuals with resistant hypertension: cognitive outcomes from the TRIUMPH trial.

Journal Article J Hypertens · July 1, 2022 BACKGROUND: Resistant hypertension is associated with increased risk of cognitive decline, stroke, and dementia. Lifestyle modification has been suggested to improve cognitive function through its salutary effects on vascular function. METHODS: Participant ... Full text Link to item Cite

Cerebrovascular Function, Vascular Risk, and Lifestyle Patterns in Resistant Hypertension.

Journal Article J Alzheimers Dis · 2022 BACKGROUND: Impaired cerebrovascular reactivity (CVR) and blunted cerebral hemodynamic recruitment are thought to be important mechanisms linking hypertension to cerebrovascular and cognitive outcomes. Few studies have examined cardiovascular or dietary co ... Full text Link to item Cite

Mental Stress-Induced Myocardial Ischemia: Prevalence, Clinical Significance, and Treatment Implications

Chapter · January 1, 2022 Mental stress produces myocardial ischemia in a significant subgroup of patients with coronary heart disease (CHD), with prevalence estimates ranging from 20% to 70% in patients with CHD. Several biobehavioral factors are involved in mental stress-induced ... Full text Cite

Effect of Exercise, Escitalopram, or Placebo on Anxiety in Patients With Coronary Heart Disease: The Understanding the Benefits of Exercise and Escitalopram in Anxious Patients With Coronary Heart Disease (UNWIND) Randomized Clinical Trial.

Journal Article JAMA Psychiatry · November 1, 2021 IMPORTANCE: Anxiety is common among patients with coronary heart disease (CHD) and is associated with worse health outcomes; however, effective treatment for anxiety in patients with CHD is uncertain. OBJECTIVE: To determine whether exercise and escitalopr ... Full text Link to item Cite

Lifestyle Interventions Reduce the Need for Guideline-Directed Antihypertensive Medication.

Conference Am J Hypertens · October 27, 2021 BACKGROUND: The 2017 ACC-AHA Hypertension Guideline recommends initiation of antihypertensive drug therapy based on blood pressure (BP) and an assessment of global cardiovascular disease (CVD) risk, but intensive lifestyle modification may lower BP to belo ... Full text Link to item Cite

Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.

Journal Article Circulation · October 12, 2021 BACKGROUND: Although lifestyle modifications generally are effective in lowering blood pressure (BP) among patients with unmedicated hypertension and in those treated with 1 or 2 antihypertensive agents, the value of exercise and diet for lowering BP in pa ... Full text Link to item Cite

Effects of Acute Exercise on Anxiety Ratings in Patients With Coronary Heart Disease and Elevated Anxiety.

Journal Article J Cardiopulm Rehabil Prev · July 1, 2021 PURPOSE: To explore individual differences in state anxiety following a single, acute bout of aerobic exercise among anxious patients with diagnosed coronary heart disease (CHD). METHODS: One hundred eighteen CHD patients with elevated symptoms of anxiety ... Full text Link to item Cite

Actigraphy-Derived Sleep Efficiency Is Associated With Endothelial Function in Men and Women With Untreated Hypertension.

Journal Article Am J Hypertens · March 11, 2021 BACKGROUND: Poor sleep quality is increasingly recognized as an important and potentially modifiable risk factor for cardiovascular disease (CVD). Impaired endothelial function may be 1 mechanism underlying the association between poor sleep and CVD risk. ... Full text Link to item Cite

The effect of reducing posttraumatic stress disorder symptoms on cardiovascular risk: Design and methodology of a randomized clinical trial.

Journal Article Contemp Clin Trials · March 2021 Posttraumatic stress disorder (PTSD) has been associated with accelerated progression of coronary heart disease (CHD). However, the underlying pathophysiological pathway has remained elusive and it is unclear whether there is a direct link between PTSD and ... Full text Link to item Cite

The role of comorbid anxiety in exercise and depression trials: Secondary analysis of the SMILE-II randomized clinical trial.

Journal Article Depress Anxiety · February 2021 OBJECTIVES: To explore the anxiolytic effects of a 4-month randomized, placebo-controlled trial of exercise and antidepressant medication in patients with major depressive disorder (MDD), and to examine the potential modifying effects of anxiety in treatin ... Full text Link to item Cite

Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100 667 Patients.

Journal Article Circulation · August 18, 2020 BACKGROUND: To quantify the association between effects of interventions on carotid intima-media thickness (cIMT) progression and their effects on cardiovascular disease (CVD) risk. METHODS: We systematically collated data from randomized, controlled trial ... Full text Link to item Cite

Vascular α1-Adrenergic Receptor Responsiveness in Masked Hypertension.

Journal Article Am J Hypertens · August 4, 2020 BACKGROUND: Masked hypertension (nonhypertensive in the clinic setting but hypertensive outside the clinic during wakefulness) is characterized by increased blood pressure in response to physical and emotional stressors that activate the sympathetic nervou ... Full text Link to item Cite

Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial.

Journal Article J Am Geriatr Soc · March 2020 OBJECTIVES: To evaluate the longer term changes in executive functioning among participants with cardiovascular disease (CVD) risk factors and cognitive impairments with no dementia (CIND) randomized to a diet and exercise intervention. DESIGN: A 2 (Exerci ... Full text Link to item Cite

Remote Therapy to Improve Outcomes in Lung Transplant Recipients: Design of the INSPIRE-III Randomized Clinical Trial.

Journal Article Transplant Direct · March 2020 BACKGROUND: Impaired functional capacity and emotional distress are associated with lower quality of life (QoL) and worse clinical outcomes in post lung transplant patients. Strategies to increase physical activity and reduce distress are needed. METHODS: ... Full text Link to item Cite

Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Previous studies have demonstrated that aerobic exercise (AE) and the Dietary Approaches to Stop Hypertension (DASH) diet can improve neurocognition. However, the mechanisms by which lifestyle improves neurocognition have not been widely studie ... Full text Link to item Cite

The modifying effects of social support on psychological outcomes in patients with heart failure.

Journal Article Health Psychol · June 2019 OBJECTIVE: We examined the modifying effects of social support on depressive symptoms and health-related quality of life (QoL) in patients receiving coping skills training (CST). METHOD: We considered the modifying effects of social support in the Coping E ... Full text Link to item Cite

Neurocognition in treatment-resistant hypertension: profile and associations with cardiovascular biomarkers.

Journal Article J Hypertens · May 2019 BACKGROUND: Hypertension in midlife has been associated with increased risk of stroke and neurocognitive decline. Few studies, however, have examined neurocognition among individuals with treatment-resistant hypertension or potential mechanisms by which tr ... Full text Link to item Cite

Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial.

Journal Article Neurology · January 15, 2019 OBJECTIVE: To determine the independent and additive effects of aerobic exercise (AE) and the Dietary Approaches to Stop Hypertension (DASH) diet on executive functioning in adults with cognitive impairments with no dementia (CIND) and risk factors for car ... Full text Link to item Cite

The Effects of Ambulatory Blood Pressure Monitoring on Sleep Quality in Men and Women With Hypertension: Dipper vs. Nondipper and Race Differences.

Journal Article Am J Hypertens · January 1, 2019 BACKGROUND: The nondipping circadian blood pressure (BP) profile is associated with both poor sleep quality and increased cardiovascular risk. The present study aimed to clarify the potential confounding effects of 24-hour ambulatory blood pressure monitor ... Full text Link to item Cite

Association Between Insulin Resistance, Plasma Leptin, and Neurocognition in Vascular Cognitive Impairment.

Journal Article J Alzheimers Dis · 2019 BACKGROUND: Greater body weight has been associated impairments in neurocognition and greater dementia risk, although the mechanisms linking weight and neurocognition have yet to be adequately delineated. OBJECTIVE: To examine metabolic mechanisms underlyi ... Full text Link to item Cite

Microvascular Endothelial Function and Neurocognition Among Adults With Major Depressive Disorder.

Journal Article Am J Geriatr Psychiatry · October 2018 BACKGROUND: Cardiovascular risk factors (CVRFs) and endothelial dysfunction have been associated independently with poorer neurocognition in middle-aged adults, particularly on tests of frontal lobe function. However, to our knowledge, no studies have exam ... Full text Link to item Cite

The role of cognitive costs, attitudes about aging, and intrinsic motivation in predicting engagement in everyday activities.

Journal Article Psychol Aging · September 2018 Engagement in cognitively demanding everyday activities has been shown to benefit cognitive health in later life. We investigated the factors that influence engagement, with specific interest in determining the extent to which the costs of engaging cogniti ... Full text Link to item Cite

Circadian hemodynamics in men and women with high blood pressure: dipper vs. nondipper and racial differences.

Journal Article J Hypertens · February 2018 OBJECTIVE: The 'nondipping' pattern of circadian blood pressure (BP) variation is an established independent predictor of adverse cardiovascular outcomes. Although this phenomenon has been widely studied, its underlying circadian hemodynamics of cardiac ou ... Full text Link to item Cite

Impact of Racial Discrimination and Hostility on Adrenergic Receptor Responsiveness in African American Adults.

Journal Article Psychosom Med · 2018 OBJECTIVE: Racial discrimination is increasingly recognized as a contributor to increased cardiovascular disease (CVD) risk among African Americans. Previous research has shown significant overlap between racial discrimination and hostility, an established ... Full text Link to item Cite

Physical activity and psychosocial function following cardiac rehabilitation: One-year follow-up of the ENHANCED study.

Journal Article Gen Hosp Psychiatry · November 2017 OBJECTIVE: To examine the long-term association between physical activity (PA) and psychosocial functioning following completion of cardiac rehabilitation (CR) among participants in the ENHANCED study. METHOD: ENHANCED was a 3-month clinical trial examinin ... Full text Link to item Cite

Association between normal or mildly reduced kidney function, cardiovascular risk and biomarkers for atherosclerosis: results from the ENCORE trial.

Journal Article Clin Kidney J · October 2017 BACKGROUND: Moderate-to-severe kidney dysfunction is associated with atherosclerotic cardiovascular disease (ASCVD). Gradations of normal or mildly reduced kidney function may also associate with ASCVD risk. METHODS: We conducted a secondary analysis using ... Full text Link to item Cite

Blood pressure reactivity to psychological stress is associated with clinical outcomes in patients with heart failure.

Journal Article Am Heart J · September 2017 INTRODUCTION: Cardiovascular (CV) reactivity to psychological stress has been implicated in the development and exacerbation of cardiovascular disease (CVD). Although high CV reactivity traditionally is thought to convey greater risk of CVD, the relationsh ... Full text Link to item Cite

Racial differences in the association between heart rate variability and left ventricular mass.

Journal Article Exp Physiol · July 1, 2017 What is the central question of this study? Decreased heart rate variability (HRV) is associated with increased cardiovascular disease (CVD) risk, including greater left ventricular mass (LVM). Despite their enhanced CVD risk profile, African Americans hav ... Full text Link to item Cite

Trauma and Autonomic Dysregulation: Episodic-Versus Systemic-Negative Affect Underlying Cardiovascular Risk in Posttraumatic Stress Disorder.

Journal Article Psychosom Med · June 2017 OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to elevated heart rate (HR) and reduced heart rate variability (HRV) in cross-sectional research. Recent evidence suggests that this link may be driven by individual differences in autonomic a ... Full text Link to item Cite

Race and sex differences in cardiovascular α-adrenergic and β-adrenergic receptor responsiveness in men and women with high blood pressure.

Journal Article J Hypertens · May 2017 OBJECTIVE: Hypertension is associated with unfavorable changes in adrenergic receptor responsiveness, but the relationship of race and sex to adrenergic receptor responsiveness in the development of cardiovascular disease is unclear. This study examined α- ... Full text Link to item Cite

Effects of exercise and stress management training on nighttime blood pressure dipping in patients with coronary heart disease: A randomized, controlled trial.

Journal Article Am Heart J · January 2017 INTRODUCTION: Blunted nighttime blood pressure (BP) dipping is prognostic of cardiovascular morbidity and mortality. Patients with coronary heart disease (CHD) are often characterized by a blunted nighttime BP dipping pattern. The present study compared th ... Full text Link to item Cite

Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial.

Journal Article Circ Heart Fail · January 2017 BACKGROUND: Heart failure (HF) is a chronic disease that compromises patients' quality of life (QoL). Interventions designed to reduce distress and improve disease self-management are needed. We evaluated the efficacy of a telephone-based coping skills tra ... Full text Link to item Cite

Lifestyle and Neurocognition in Older Adults With Cardiovascular Risk Factors and Cognitive Impairment.

Journal Article Psychosom Med · 2017 OBJECTIVE: The aim of the study was to determine the relationship of lifestyle factors and neurocognitive functioning in older adults with vascular risk factors and cognitive impairment, no dementia (CIND). METHODS: One hundred sixty adults (M [SD] = 65.4 ... Full text Link to item Cite

Trauma and Autonomic Dysregulation: Episodic - Versus Systemic - Negative Affect Underlying Cardiovascular Risk in Posttraumatic Stress Disorder.

Journal Article Psychosom Med · December 9, 2016 OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to elevated heart rate (HR) and reduced heart-rate variability (HRV) in cross-sectional research. Recent evidence suggests that this link may be driven by individual differences in autonomic a ... Full text Link to item Cite

Influence of Kidney Function on Blood Pressure Response to Lifestyle Modifications: Secondary Analysis From the Exercise and Nutritional Interventions for Cardiovascular Health (ENCORE) Trial.

Journal Article J Clin Hypertens (Greenwich) · December 2016 The kidney is an important regulator of blood pressure (BP). To determine whether BP response to lifestyle modification varies across normal ranges of kidney function, the authors examined the moderating role of estimated glomerular filtration rate (eGFR) ... Full text Link to item Cite

Hemodynamics and Vascular Hypertrophy in African Americans and Caucasians With High Blood Pressure.

Journal Article Am J Hypertens · December 1, 2016 BACKGROUND: Hypertension in African Americans is characterized by greater systemic vascular resistance (SVR) compared with Caucasian Americans, but the responsible mechanisms are not known. The present study sought to determine if peripheral vascular hyper ... Full text Link to item Cite

Examining the Crux of Autonomic Dysfunction in Posttraumatic Stress Disorder: Whether Chronic or Situational Distress Underlies Elevated Heart Rate and Attenuated Heart Rate Variability.

Journal Article Psychosom Med · September 2016 OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to elevated heart rate (HR) and reduced heart rate variability (HRV) in cross-sectional research. Using ecological momentary assessment and minute-to-minute HRV/HR monitoring, we examined whet ... Full text Link to item Cite

Reactive hyperemia is associated with adverse clinical outcomes in heart failure.

Journal Article Am Heart J · August 2016 INTRODUCTION: Impaired endothelial function, as assessed by brachial artery flow-mediated dilation (FMD), is an established risk factor for cardiovascular events. FMD is impaired in heart failure (HF) patients, but less is known about hyperemic brachial ar ... Full text Link to item Cite

Effects of Exercise and Sertraline on Measures of Coronary Heart Disease Risk in Patients With Major Depression: Results From the SMILE-II Randomized Clinical Trial.

Journal Article Psychosom Med · June 2016 OBJECTIVE: To assess the effects of supervised and home-based aerobic exercise training, and antidepressant pharmacotherapy (sertraline) on coronary heart disease (CHD) risk factors in a sample of participants with major depressive disorder (MDD). METHODS: ... Full text Link to item Cite

Treatment of anxiety in patients with coronary heart disease: Rationale and design of the UNderstanding the benefits of exercise and escitalopram in anxious patients WIth coroNary heart Disease (UNWIND) randomized clinical trial.

Journal Article Am Heart J · June 2016 BACKGROUND: Anxiety is highly prevalent among patients with coronary heart disease (CHD), and there is growing evidence that high levels of anxiety are associated with worse prognosis. However, few studies have evaluated the efficacy of treating anxiety in ... Full text Link to item Cite

Enhancing Cardiac Rehabilitation With Stress Management Training: A Randomized, Clinical Efficacy Trial.

Journal Article Circulation · April 5, 2016 BACKGROUND: Cardiac rehabilitation (CR) is the standard of care for patients with coronary heart disease. Despite considerable epidemiological evidence that high stress is associated with worse health outcomes, stress management training (SMT) is not inclu ... Full text Link to item Cite

An investigation of vago-regulatory and health-behavior accounts for increased inflammation in posttraumatic stress disorder.

Journal Article J Psychosom Res · April 2016 OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to chronic inflammation, a condition that poses a risk for cardiovascular disease. Attenuated vagal activity has been proposed as a potential mediator of PTSD and inflammation, although associ ... Full text Link to item Cite

Fitting Nonlinear Ordinary Differential Equation Models with Random Effects and Unknown Initial Conditions Using the Stochastic Approximation Expectation-Maximization (SAEM) Algorithm.

Journal Article Psychometrika · March 2016 The past decade has evidenced the increased prevalence of irregularly spaced longitudinal data in social sciences. Clearly lacking, however, are modeling tools that allow researchers to fit dynamic models to irregularly spaced data, particularly data that ... Full text Link to item Cite

Exploring the relationship between posttraumatic stress disorder symptoms and momentary heart rate variability.

Journal Article J Psychosom Res · March 2016 OBJECTIVE: Exposure to trauma-related cues has been associated with a prolonged decrease in heart rate variability (HRV) under laboratory conditions, however the relationship between PTSD symptoms and HRV has not been evaluated during everyday life. The pr ... Full text Link to item Cite

Impaired hippocampal-dependent memory and reduced parvalbumin-positive interneurons in a ketamine mouse model of schizophrenia.

Journal Article Schizophr Res · March 2016 The hippocampus of patients with schizophrenia displays aberrant excess neuronal activity which affects cognitive function. Animal models of the illness have recapitulated the overactivity in the hippocampus, with a corresponding regionally localized reduc ... Full text Link to item Cite

Deletion of Melanin Concentrating Hormone Receptor-1 disrupts overeating in the presence of food cues.

Journal Article Physiol Behav · December 1, 2015 Exposure to environmental cues associated with food can evoke eating behavior in the absence of hunger. This capacity for reward cues to promote feeding behaviors under sated conditions can be examined in the laboratory using cue-potentiated feeding (CPF). ... Full text Link to item Cite

Lifestyle modification for resistant hypertension: The TRIUMPH randomized clinical trial.

Journal Article Am Heart J · November 2015 BACKGROUND: Resistant hypertension (RH) is a growing health burden in this country affecting as many as 1 in 5 adults being treated for hypertension. Resistant hypertension is associated with increased risk of adverse cardiovascular disease (CVD) events an ... Full text Link to item Cite

Bayesian Analysis of Ambulatory Blood Pressure Dynamics with Application to Irregularly Spaced Sparse Data.

Journal Article Ann Appl Stat · September 2015 Ambulatory cardiovascular (CV) measurements provide valuable insights into individuals' health conditions in "real-life," everyday settings. Current methods of modeling ambulatory CV data do not consider the dynamic characteristics of the full data set and ... Full text Link to item Cite

Endothelial function in postmenopausal women with nighttime systolic hypertension.

Journal Article Menopause · August 2015 OBJECTIVE: Hypertension becomes more prevalent in women during their postmenopausal years. Nighttime systolic blood pressure (SBP) is especially predictive of adverse cardiac events, and the relationship between rising nighttime SBP and cardiovascular risk ... Full text Link to item Cite

Orthostatic hypotension in young adults with and without posttraumatic stress disorder.

Journal Article Psychol Trauma · May 2015 The purpose of this research is (a) to evaluate differences in orthostatic hypotension (OH) among young adults with and without posttraumatic stress disorder (PTSD) and (b) to examine whether group differences may be attributable to behavioral risk factors ... Full text Link to item Cite

ENHANCING EXERCISE-BASED CARDIAC REHABILITATION WITH STRESS MANAGEMENT TRAINING

Journal Article ANNALS OF BEHAVIORAL MEDICINE · April 1, 2015 Link to item Cite

Work and home stress: associations with anxiety and depression symptoms.

Journal Article Occup Med (Lond) · March 2015 BACKGROUND: In the evolving work environment of global competition, the associations between work and home stress and psychological well-being are not well understood. AIMS: To examine the impact of psychosocial stress at work and at home on anxiety and de ... Full text Link to item Cite

Association of depressive and anxiety symptoms with 24-hour urinary catecholamines in individuals with untreated high blood pressure.

Journal Article Psychosom Med · 2015 OBJECTIVE: Depression and anxiety are considered risk factors for cardiovascular disease (CVD). The explanatory mechanisms, however, are still to be characterized. One proposed pathophysiological pathway is dysregulation of the autonomic nervous system, in ... Full text Link to item Cite

Posttraumatic stress, heart rate variability, and the mediating role of behavioral health risks.

Journal Article Psychosom Med · October 2014 OBJECTIVE: Posttraumatic stress disorder (PTSD) has been linked to reduced heart rate variability (HRV), which is in turn a risk factor for cardiovascular disease and death. Although hyperarousal and anxiety are thought to underlie this association, behavi ... Full text Link to item Cite

Behavioral health mediators of the link between posttraumatic stress disorder and dyslipidemia.

Journal Article J Psychosom Res · July 2014 OBJECTIVES: Posttraumatic stress disorder (PTSD) has been linked to dyslipidemia, which is a major risk factor for coronary artery disease. Although this link is thought to reflect response to heightened stress, behavioral health risks, including smoking, ... Full text Link to item Cite

Pulmonary artery thrombus in a premature neonate treated with recombinant tissue plasminogen activator.

Journal Article J Perinatol · July 2014 Pulmonary artery thrombus is a rarely reported complication in premature neonates. The management of life-threatening thrombotic events in neonates is controversial, especially regarding the use of thrombolytics versus anticoagulation alone for treatment. ... Full text Link to item Cite

The long-term effects of lifestyle change on blood pressure: One-year follow-up of the ENCORE study.

Journal Article Am J Hypertens · May 2014 BACKGROUND: There is a paucity of data describing the sustained benefits of lifestyle interventions on health behaviors and blood pressure (BP). METHODS: We examined the persistence of changes in health habits and BP in the ENCORE study, a trial in which 1 ... Full text Link to item Cite

Impact of sleep complaints and depression outcomes among participants in the standard medical intervention and long-term exercise study of exercise and pharmacotherapy for depression.

Journal Article J Nerv Ment Dis · February 2014 The aim of this study was to examine the effects of exercise and sertraline on disordered sleep in patients with major depressive disorder (MDD). Methods The Standard Medical Intervention and Long-term Exercise study randomized the patients with MDD (n = 2 ... Full text Link to item Cite

Biobehavioral interventions in heart failure

Chapter · January 1, 2014 Heart failure (HF) is a medical condition in which the heart loses its ability to pump blood efficiently. This chapter focuses on HF caused due to systolic dysfunction of the left ventricle, which is the most common and widely studied type of HF. It begins ... Full text Cite

Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.

Journal Article J Am Heart Assoc · March 19, 2013 BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD) patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence of depression and anxiety. We examined whether anxiety is associated with inc ... Full text Open Access Link to item Cite

Psychosocial correlates of atrial natriuretic peptide: a marker of vascular health.

Journal Article Ann Behav Med · February 2013 BACKGROUND: Psychosocial factors have been associated with cardiovascular outcomes, but few studies have examined the association between psychosocial function and natriuretic peptides. PURPOSE: The purpose of this study is to determine the predictive valu ... Full text Link to item Cite

The effect of job strain on nighttime blood pressure dipping among men and women with high blood pressure.

Journal Article Scand J Work Environ Health · January 2013 Featured Publication OBJECTIVES: Blunted nighttime blood pressure dipping is an established cardiovascular risk factor. This study examined the effect of job strain on nighttime blood pressure dipping among men and women with high blood pressure. METHODS: The sample consisted ... Full text Link to item Cite

Can lifestyle modification improve neurocognition? Rationale and design of the ENLIGHTEN clinical trial.

Journal Article Contemp Clin Trials · January 2013 BACKGROUND: Risk factors for cardiovascular disease (CVD) not only increase the risk for clinical CVD events, but also are associated with a cascade of neurophysiologic and neuroanatomic changes that increase the risk of cognitive impairment and dementia. ... Full text Link to item Cite

Reproducibility of blood pressure dipping: relation to day-to-day variability in sleep quality.

Journal Article J Am Soc Hypertens · 2013 Previous studies of the reproducibility of blood pressure (BP) dipping have yielded inconsistent results. Few have examined factors that may influence day-to-day differences in dipping. Ambulatory BP monitoring was performed on three occasions, approximate ... Full text Link to item Cite

Reply

Journal Article Journal of the American College of Cardiology · December 11, 2012 Full text Cite

The influence of endothelial function and myocardial ischemia on peak oxygen consumption in patients with coronary artery disease

Journal Article International Journal of Vascular Medicine · November 19, 2012 Impaired endothelial function has been shown to limit exercise in coronary artery disease (CAD) patients and has been implicated in myocardial ischemia. However, the association of endothelial function and ischemia on peak exercise oxygen consumption (VO2) ... Full text Cite

Determinants and consequences of adherence to the dietary approaches to stop hypertension diet in African-American and white adults with high blood pressure: results from the ENCORE trial.

Journal Article J Acad Nutr Diet · November 2012 BACKGROUND: Although the Dietary Approaches to Stop Hypertension (DASH) diet is an accepted nonpharmacologic treatment for hypertension, little is known about what patient characteristics affect dietary adherence and what level of adherence is needed to re ... Full text Link to item Cite

Nighttime blood pressure dipping in postmenopausal women with coronary heart disease.

Journal Article Am J Hypertens · October 2012 Featured Publication BACKGROUND: Blunted nighttime blood pressure (BP) dipping is prognostic of cardiovascular morbidity and mortality. This relationship may be stronger among women than men. The present study hypothesized that coronary artery disease (CAD) and advancing age w ... Full text Link to item Cite

Exercise and pharmacological treatment of depressive symptoms in patients with coronary heart disease: results from the UPBEAT (Understanding the Prognostic Benefits of Exercise and Antidepressant Therapy) study.

Journal Article J Am Coll Cardiol · September 18, 2012 Featured Publication OBJECTIVES: The aim of this study was to assess the efficacy of exercise and antidepressant medication in reducing depressive symptoms and improving cardiovascular biomarkers in depressed patients with coronary heart disease. BACKGROUND: Although there is ... Full text Link to item Cite

Sex differences in the endothelial function of untreated hypertension.

Journal Article J Clin Hypertens (Greenwich) · April 2012 Featured Publication Vascular endothelial dysfunction is associated with increased risk for adverse cardiovascular (CV) events. However, less is known about sex differences in the endothelial function of untreated hypertensive individuals. The purpose of this study was to asse ... Full text Link to item Cite

Ethnic differences in the effects of the DASH diet on nocturnal blood pressure dipping in individuals with high blood pressure.

Journal Article Am J Hypertens · December 2011 Featured Publication BACKGROUND: Ethnic differences in nocturnal blood pressure (BP) dipping may contribute to the increased risk for adverse cardiovascular events noted in African Americans (AAs). The DASH (Dietary Approaches to Stop Hypertension) diet has been shown to be ef ... Full text Link to item Cite

Blood pressure dipping: ethnicity, sleep quality, and sympathetic nervous system activity.

Journal Article Am J Hypertens · September 2011 Featured Publication BACKGROUND: Blunted blood pressure (BP) dipping is an established predictor of adverse cardiovascular outcomes. Although blunted BP dipping is more common in African Americans than whites, the factors contributing to this ethnic difference are not well und ... Full text Link to item Cite

Association of vascular health and neurocognitive performance in overweight adults with high blood pressure.

Journal Article J Clin Exp Neuropsychol · June 2011 Featured Publication The relationship between vascular health--including flow-mediated dilation (FMD) and intima medial thickness (IMT)--and neurocognitive performance was examined in a sample of 124 sedentary, middle-aged adults with high blood pressure (systolic blood pressu ... Full text Link to item Cite

Coping effectively with heart failure (COPE-HF): design and rationale of a telephone-based coping skills intervention.

Journal Article J Card Fail · March 2011 Featured Publication BACKGROUND: Coping Effectively with Heart Failure (COPE-HF) is an ongoing randomized clinical trial funded by the National Institutes of Health to evaluate if a coping skills training (CST) intervention will result in improved health status and quality of ... Full text Link to item Cite

The DASH diet and insulin sensitivity.

Journal Article Curr Hypertens Rep · February 2011 Lifestyle modifications, including adoption of the Dietary Approaches to Stop Hypertension (DASH) dietary pattern, weight loss in individuals who are overweight or obese, and physical activity, are effective in the prevention and treatment of hypertension. ... Full text Link to item Cite

Worsening depressive symptoms are associated with adverse clinical outcomes in patients with heart failure.

Journal Article J Am Coll Cardiol · January 25, 2011 Featured Publication OBJECTIVES: The purpose of this study was to assess the impact of changes in symptoms of depression over a 1-year period on subsequent clinical outcomes in heart failure (HF) patients. BACKGROUND: Emerging evidence shows that clinical depression, which is ... Full text Link to item Cite

Household responsibilities, income, and ambulatory blood pressure among working men and women.

Journal Article Psychosom Med · 2011 OBJECTIVE: To test the hypothesis that a greater perceived responsibility for household tasks and a greater number of hours spent doing these tasks would be associated with elevated ambulatory systolic (SBP) and diastolic blood pressure (DBP). The connecti ... Full text Link to item Cite

Exercise and pharmacotherapy in patients with major depression: one-year follow-up of the SMILE study.

Journal Article Psychosom Med · 2011 OBJECTIVE: To examine a 1-year follow-up of a 4-month, controlled clinical trial of exercise and antidepressant medication in patients with major depressive disorder (MDD). METHODS: In the original study, 202 sedentary adults with MDD were randomized to: a ... Full text Link to item Cite

Cerebrovascular risk factors and cerebral hyperintensities among middle-aged and older adults with major depression.

Journal Article Am J Geriatr Psychiatry · September 2010 OBJECTIVES: To examine the association between cerebral hyperintensities and cerebrovascular risk factors (CVRF) among middle-aged and older adults with major depressive disorder (MDD). METHODS: Thirty patients (aged 55-77 years) with MDD and no history of ... Full text Link to item Cite

Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure.

Journal Article Hypertension · June 2010 High blood pressure increases the risks of stroke, dementia, and neurocognitive dysfunction. Although aerobic exercise and dietary modifications have been shown to reduce blood pressure, no randomized trials have examined the effects of aerobic exercise co ... Full text Open Access Link to item Cite

Effects of the dietary approaches to stop hypertension diet alone and in combination with exercise and caloric restriction on insulin sensitivity and lipids.

Journal Article Hypertension · May 2010 Featured Publication This study examined the effects of the Dietary Approaches to Stop Hypertension (DASH) diet on insulin sensitivity and lipids. In a randomized control trial, 144 overweight (body mass index: 25 to 40) men (n=47) and women (n=97) with high blood pressure (13 ... Full text Link to item Cite

Aerobic exercise and neurocognitive performance: a meta-analytic review of randomized controlled trials.

Journal Article Psychosom Med · April 2010 OBJECTIVES: To assess the effects of aerobic exercise training on neurocognitive performance. Although the effects of exercise on neurocognition have been the subject of several previous reviews and meta-analyses, they have been hampered by methodological ... Full text Open Access Link to item Cite

Cardiovascular hemodynamics during stress in premenopausal versus postmenopausal women.

Journal Article Menopause · March 2010 Featured Publication OBJECTIVE: After menopause, women are at an increased risk of cardiovascular disease. The present study assessed cardiovascular hemodynamics in premenopausal versus postmenopausal women, with a focus on systemic vascular resistance (SVR) at rest and during ... Full text Link to item Cite

Posttraumatic stress disorder, cardiovascular, and metabolic disease: a review of the evidence.

Journal Article Ann Behav Med · February 2010 Featured Publication BACKGROUND: Posttraumatic stress disorder (PTSD) is a significant risk factor for cardiovascular and metabolic disease. PURPOSE: The purpose of the current review is to evaluate the evidence suggesting that PTSD increases cardiovascular and metabolic risk ... Full text Link to item Cite

Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study.

Journal Article Arch Intern Med · January 25, 2010 Featured Publication BACKGROUND: Although the DASH (Dietary Approaches to Stop Hypertension) diet has been shown to lower blood pressure (BP) in short-term feeding studies, it has not been shown to lower BP among free-living individuals, nor has it been shown to alter cardiova ... Full text Link to item Cite

Cardiovascular disease risk, vascular health and erectile dysfunction among middle-aged, clinically depressed men.

Journal Article Int J Impot Res · 2010 Featured Publication Erectile dysfunction (ED) is especially common in men with major depressive disorder (MDD). This study examined the extent to which risk factors for cardiovascular disease (CVD) and vascular endothelial dysfunction were associated with ED severity in MDD p ... Full text Link to item Cite

Prognosis after change in left ventricular ejection fraction during mental stress testing in patients with stable coronary artery disease.

Journal Article Am J Cardiol · January 1, 2010 Previous studies of patients with stable coronary artery disease have demonstrated that decreases in the left ventricular ejection fraction (LVEF) during acute mental stress are predictive of adverse clinical outcomes. The aim of the present study was to e ... Full text Link to item Cite

Enhancing standard cardiac rehabilitation with stress management training: background, methods, and design for the enhanced study.

Journal Article J Cardiopulm Rehabil Prev · 2010 PURPOSE: Enhancing Standard Cardiac Rehabilitation with Stress Management Training in Patients with Heart Disease (ENHANCED) is a randomized clinical trial funded by the National Heart Lung and Blood Institute to evaluate the effects of stress management t ... Full text Link to item Cite

Coping styles in heart failure patients with depressive symptoms.

Journal Article J Psychosom Res · October 2009 Featured Publication OBJECTIVE: Elevated depressive symptoms have been linked to poorer prognosis in heart failure (HF) patients. Our objective was to identify coping styles associated with depressive symptoms in HF patients. METHODS: A total of 222 stable HF patients (32.75% ... Full text Link to item Cite

Effects of aerobic exercise on sexual functioning in depressed adults

Journal Article Mental Health and Physical Activity · June 1, 2009 Objective: Exercise appears to be generally comparable to antidepressant medication in reducing depressive symptoms. The current study examines the effects of aerobic exercise, compared to antidepressant medication and placebo pill, on sexual function amon ... Full text Cite

Association between n-3 fatty acid consumption and ventricular ectopy after myocardial infarction.

Journal Article Am J Clin Nutr · May 2009 BACKGROUND: n-3 (omega-3) Fatty acids are associated with a reduced risk of cardiovascular disease; however, the relation between dietary intake of n-3 fatty acids and ventricular arrhythmias has not been investigated among acute post-myocardial infarction ... Full text Link to item Cite

Intima-media thickness and age of first depressive episode.

Journal Article Biol Psychol · March 2009 Featured Publication BACKGROUND: Late life depression, including patients with vascular depression, has been associated with higher levels of intima-media thickness (IMT). Although individuals with vascular depression tend to report a later onset of depression, the relationshi ... Full text Link to item Cite

Ethnic differences in the treatment of depression in patients with ischemic heart disease.

Journal Article Am Heart J · January 2009 OBJECTIVE: The aim of this study is to examine ethnic differences in depressive symptoms and antidepressant treatment in a cohort of patients undergoing diagnostic coronary angiography. BACKGROUND: Coronary heart disease (CHD) is the leading cause of morta ... Full text Link to item Cite

Independent prognostic value of echocardiography and N-terminal pro-B-type natriuretic peptide in patients with heart failure.

Journal Article Am Heart J · December 2008 BACKGROUND: Echocardiographic indices of cardiac structure and function and natriuretic peptide levels are strong predictors of mortality in patients with heart failure. Whether cardiac ultrasound and natriuretic peptides provide independent prognostic inf ... Full text Link to item Cite

Exercise fails to improve neurocognition in depressed middle-aged and older adults.

Journal Article Med Sci Sports Exerc · July 2008 PURPOSE: Although cross-sectional studies have demonstrated an association between higher levels of aerobic fitness and improved neurocognitive function, there have been relatively few interventional studies investigating this relationship, and results hav ... Full text Link to item Cite

Formation of excitatory and inhibitory associations between absent events.

Journal Article J Exp Psychol Anim Behav Process · July 2008 Considerable evidence indicates that associations may be formed between two events even when one or both of them is absent at the time of learning. Previously, some researchers asserted that excitatory associations are formed when associatively activated r ... Full text Link to item Cite

Laboratory-based blood pressure recovery is a predictor of ambulatory blood pressure.

Journal Article Biol Psychol · March 2008 The recovery phase of the stress response is an individual difference characteristic that may predict cardiovascular risk. The purpose of this study was to examine whether laboratory-based blood pressure (BP) recovery predicts ambulatory BP (ABP). One hund ... Full text Link to item Cite

C-reactive protein and heart rate variability following myocardial infarction

Journal Article ANNALS OF BEHAVIORAL MEDICINE · March 1, 2008 Link to item Cite

Response to letters to the editor [3]

Journal Article Psychosomatic Medicine · February 1, 2008 Full text Cite

Effects of exercise and weight loss on depressive symptoms among men and women with hypertension.

Journal Article J Psychosom Res · November 2007 OBJECTIVE: This study aimed to investigate changes in depressive symptoms in hypertensive individuals participating in an exercise and weight loss intervention. METHODS: This study involved 133 sedentary men and women with high blood pressure (BP; 130-180 ... Full text Link to item Cite

Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women.

Journal Article Arterioscler Thromb Vasc Biol · August 2007 Featured Publication OBJECTIVE: We evaluated age and coronary heart disease (CHD) as potential moderators of the effects of 17beta-estradiol on vascular endothelial function in postmenopausal women. METHODS AND RESULTS: In a double-blind crossover design, 100 postmenopausal wo ... Full text Link to item Cite

Relationship of depression to death or hospitalization in patients with heart failure.

Journal Article Arch Intern Med · February 26, 2007 Featured Publication BACKGROUND: Depression is widely recognized as a risk factor in patients with coronary heart disease. However, patients with heart failure (HF) have been less frequently studied, and the effect of depression on prognosis, independent of disease severity, i ... Full text Link to item Cite

Exercise and pharmacotherapy in the treatment of major depressive disorder.

Journal Article Psychosom Med · 2007 OBJECTIVE: To assess whether patients receiving aerobic exercise training performed either at home or in a supervised group setting achieve reductions in depression comparable to standard antidepressant medication (sertraline) and greater reductions in dep ... Full text Link to item Cite

Ventricular ectopy: impact of self-reported stress after myocardial infarction.

Journal Article Am Heart J · January 2007 BACKGROUND: Although psychologic stress has been implicated in the pathogenesis of ventricular arrhythmias, the relationship between self-reported stress and ventricular ectopy has not been evaluated under naturalistic conditions in acute post-myocardial i ... Full text Link to item Cite

Understanding prognostic benefits of exercise and antidepressant therapy for persons with depression and heart disease: the UPBEAT study--rationale, design, and methodological issues.

Journal Article Clin Trials · 2007 BACKGROUND: Depression is relatively common in patients with coronary heart disease (CHD) and is associated with worse prognosis. Recently there has been interest in evaluating the impact of treating depression on clinical outcomes. Anti-depressant medicat ... Full text Link to item Cite

Cerebrovascular risk factors, vascular disease, and neuropsychological outcomes in adults with major depression.

Journal Article Psychosom Med · 2007 OBJECTIVE: To investigate the relationship of cerebrovascular risk factors (CVRFs), endothelial function, carotid artery intima medial thickness (IMT), and neuropsychological performance in a sample of 198 middle-aged and older individuals with major depre ... Full text Link to item Cite

Blood Pressure

Journal Article · January 1, 2007 Blood pressure is one of the most widely recorded physiological functions of the body. It is a measurement of the pulsatile pressure fluctuations in the arterial system that provides the driving force behind blood flow to the tissues. It is one of the body ... Full text Cite

Changes in plasma volume associated with mental stress ischemia in patients with coronary artery disease.

Journal Article Int J Psychophysiol · August 2006 Psychological stress has been shown to trigger angina and myocardial ischemia in patients with coronary artery disease. However, the mechanisms by which stress may trigger cardiac events has yet to be fully elucidated. Twenty five patients underwent radion ... Full text Link to item Cite

Depression and prognosis in cardiac patients

Chapter · January 1, 2006 Coronary heart disease (CHD) is the leading cause of death in the USA and Europe [1, 2]. In roughly half the cases, the first clinical manifestations of CHD – myocardial infarction (MI) or sudden death – are catastrophic. These events are sudden, unexpecte ... Full text Cite

Association between hot flashes, sleep complaints, and psychological functioning among healthy menopausal women.

Journal Article Int J Behav Med · 2006 Self-report data suggest that sleep hot flashes among menopausal women are associated with sleep problems and in turn impaired psychological functioning. However, few studies have examined these relations with physiologic hot flash measures. A total of 41 ... Full text Link to item Cite

Impaired endothelial function in coronary heart disease patients with depressive symptomatology.

Journal Article J Am Coll Cardiol · August 16, 2005 Featured Publication OBJECTIVES: The purpose of this study was to assess whether depressive symptomatology was associated with vascular endothelial dysfunction in patients with coronary heart disease (CHD). BACKGROUND: In patients with CHD, the presence of depression is associ ... Full text Link to item Cite

Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial.

Journal Article JAMA · April 6, 2005 CONTEXT: Observational studies have shown that psychosocial factors are associated with increased risk for cardiovascular morbidity and mortality, but the effects of behavioral interventions on psychosocial and medical end points remain uncertain. OBJECTIV ... Full text Link to item Cite

Social support and coronary heart disease: epidemiologic evidence and implications for treatment.

Journal Article Psychosom Med · 2005 OBJECTIVE: The present paper reviews theories of social support and evidence for the role of social support in the development and progression of coronary heart disease (CHD). METHODS: Articles for the primary review of social support as a risk factor were ... Full text Link to item Cite

Emotional antecedents of hot flashes during daily life.

Journal Article Psychosom Med · 2005 OBJECTIVE: Hot flashes are among the most frequently reported menopausal symptoms. However, little is known about factors associated with their occurrence. Moreover, despite the wide use of self-report hot flash measures, little is known about their concor ... Full text Link to item Cite

Lifestyle approaches to the treatment of hypertension

Conference PSYCHOLOGICAL APPROACHES TO CHRONIC DISEASE MANAGEMENT · January 1, 2005 Link to item Cite

Association between exercise capacity and left ventricular geometry in overweight patients with mild systemic hypertension.

Journal Article Am J Cardiol · November 15, 2004 The purpose of this study was to determine the relation between left ventricular (LV) geometry and exercise capacity in unmedicated, hypertensive patients. Analysis of the data revealed peak oxygen consumption (ml kg(-1) min(-1)) for concentric hypertrophy ... Full text Link to item Cite

Depression and anxiety symptoms are related to increased 24-hour urinary norepinephrine excretion among healthy middle-aged women.

Journal Article J Psychosom Res · October 2004 Featured Publication OBJECTIVE: Depression is a risk factor for morbidity and mortality in a variety of populations, and anxiety has also been associated with risk of mortality among cardiac patients. Dysfunction of the autonomic nervous system may be involved in this risk. Th ... Full text Link to item Cite

Vigilance to a persisting personal threat: unmasking cardiovascular consequences in adolescents with the Social Competence Interview.

Journal Article Psychophysiology · September 2004 We report the first systematic study of hemodynamic responses to the Social Competence Interview, using the original Ewart protocol, which focuses attention on a persisting personal threat. Physiologic changes in 212 African American and Caucasian urban ad ... Full text Link to item Cite

Effects of daily stress on autonomic cardiac control in patients with coronary artery disease.

Journal Article Am J Cardiol · May 15, 2004 Emotional stress has been implicated in the development and progression of coronary artery disease, with 1 proposed causal pathway being changes in cardiac autonomic tone. One hundred thirty-five patients with coronary artery disease underwent 48 hours of ... Full text Link to item Cite

Relationship of ethnicity, gender, and ambulatory blood pressure to pain sensitivity: effects of individualized pain rating scales.

Journal Article J Pain · April 2004 UNLABELLED: A growing literature has reported significant reductions in pain sensitivity associated with increasing levels of blood pressure. However, most of this research has been limited to casual blood pressure assessments in white men. The present stu ... Full text Link to item Cite

Relationship between exercise systolic blood pressure and left ventricular geometry in overweight, mildly hypertensive patients.

Journal Article J Hypertens · February 2004 OBJECTIVE: To examine the association between the graded exercise systolic blood pressure (SBP) response and left ventricular (LV) geometric structure in patients with untreated mild hypertension. PARTICIPANTS: The study included 80 sedentary, overweight p ... Full text Link to item Cite

Effects of exercise, diet and weight loss on high blood pressure.

Journal Article Sports Med · 2004 High blood pressure (BP) is a major health problem in the US, affecting more than 50 million people. Although high BP is among the most common reasons for outpatient visits, BP control is often inadequate. It is well established that BP can be lowered phar ... Full text Link to item Cite

Ethnic differences in left ventricular structure: relations to hemodynamics and diurnal blood pressure variation.

Journal Article Am J Hypertens · January 2004 Featured Publication BACKGROUND: Previous studies have suggested that African Americans have a greater left ventricular relative wall thickness than whites with similar levels of blood pressure (BP), whereas other investigators have documented an attenuated nocturnal decline i ... Full text Link to item Cite

Transdermal versus oral estrogen therapy in postmenopausal smokers: hemodynamic and endothelial effects.

Journal Article Obstet Gynecol · January 2004 OBJECTIVE: To test the hypothesis that, in postmenopausal smokers, transdermal estrogen would be more effective than oral estrogen in reducing blood pressure (BP) and vascular and norepinephrine responses to stress and in increasing endothelial function an ... Full text Link to item Cite

Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment.

Journal Article Psychosom Med · 2004 OBJECTIVE: The present paper reviews the evidence that depression is a risk factor for the development and progression of coronary artery disease (CAD). METHODS: MEDLINE searches and reviews of bibliographies were used to identify relevant articles. Articl ... Full text Link to item Cite

Hostility is related to blunted beta-adrenergic receptor responsiveness among middle-aged women.

Journal Article Psychosom Med · 2004 Featured Publication OBJECTIVE: Based on previous findings in men, the hypothesis that hostility would be associated with blunted responsiveness of cardiovascular beta-adrenergic receptors was tested in a study sample of middle-aged women. The roles of the sympathetic nervous ... Full text Link to item Cite

Effects of exercise and weight loss on cardiac risk factors associated with syndrome X.

Journal Article Arch Intern Med · September 8, 2003 BACKGROUND: Patients with high blood pressure (BP) often exhibit syndrome X, an aggregation of abnormalities in carbohydrate and lipoprotein metabolism associated with increased risk of coronary heart disease (CHD). The present study evaluated the effects ... Full text Link to item Cite

Depression and increased myocardial ischemic activity in patients with ischemic heart disease.

Journal Article Am Heart J · July 2003 BACKGROUND: Depression is relatively common in patients with ischemic heart disease (IHD) and is associated with increased risk of mortality and morbidity. However, the mechanisms by which depression adversely affects clinical outcomes of patients with IHD ... Full text Link to item Cite

Sympathoadrenergic mechanisms in reduced hemodynamic stress responses after exercise.

Journal Article Med Sci Sports Exerc · June 2003 PURPOSE: This study examines the acute effects of moderate aerobic exercise on 1) hemodynamic and sympathetic activity during behavioral stress and 2) beta-adrenergic receptor responsivity in a biracial sample of 24 sedentary adults. METHODS: Before and af ... Full text Link to item Cite

Ethnic differences in the hemodynamic mechanisms of ambulatory blood pressure regulation.

Journal Article Am J Hypertens · April 2003 Featured Publication BACKGROUND: African Americans typically exhibit greater systemic vascular resistance (SVR) than do white individuals in response to laboratory challenges that raise blood pressure (BP). However, ethnic differences in ambulatory blood pressure (ABP) regulat ... Full text Link to item Cite

Biological correlates of abuse in women with premenstrual dysphoric disorder and healthy controls.

Journal Article Psychosom Med · 2003 OBJECTIVE: To examine the biological correlates associated with histories of sexual or physical abuse in women meeting DSM criteria for premenstrual dysphoric disorder (PMDD) and in healthy, non-PMDD controls. METHODS: Twenty-eight women with prospectively ... Full text Link to item Cite

Hostility, social support, and adrenergic receptor responsiveness among African-American and white men and women.

Journal Article Psychosom Med · 2003 OBJECTIVE: We examined the relationship between beta-adrenergic receptor responsiveness and hostility and social support in African American and white men and women. METHODS: The participants were 149 men and women, aged 25 to 45 years with SBP < 160 and D ... Full text Link to item Cite

Effects of perceived racism and anger inhibition on ambulatory blood pressure in African Americans.

Journal Article Psychosom Med · 2003 Featured Publication OBJECTIVE: Hypertension is more prevalent in African Americans compared with Americans of European descent. Preliminary evidence indicates that perceived racism may play a role in elevated blood pressure in African Americans. The present study examined whe ... Full text Link to item Cite

Blunted nighttime blood pressure dipping in postmenopausal women in reply

Journal Article American Journal of Hypertension · July 2002 Full text Cite

Reduction of left ventricular hypertrophy after exercise and weight loss in overweight patients with mild hypertension.

Journal Article Arch Intern Med · June 24, 2002 BACKGROUND: Hypertrophy and concentric remodeling of the left ventricle are important manifestations of hypertension that are associated with increased morbidity and mortality. Although lifestyle interventions are efficacious in lowering blood pressure, ev ... Full text Link to item Cite

Biobehavioral approaches to the treatment of essential hypertension.

Journal Article J Consult Clin Psychol · June 2002 Despite recent advances in the medical management of hypertension, chronically elevated blood pressure remains a major health problem in the United States, affecting almost 50 million Americans. It is widely recognized that lifestyle factors contribute to ... Link to item Cite

Changes in hemodynamics and left ventricular structure after menopause.

Journal Article Am J Cardiol · April 1, 2002 Featured Publication To evaluate the cardiovascular changes associated with menopause, we studied hemodynamics at rest, ambulatory blood pressure, and left ventricular structure in a biracial cohort of pre- and postmenopausal women of similar age, race, weight, and blood press ... Full text Link to item Cite

Nighttime blood pressure dipping: the role of the sympathetic nervous system.

Journal Article Am J Hypertens · February 2002 Featured Publication There is a marked diurnal variation in blood pressure (BP), with BP dipping to its lowest levels during nighttime sleep. A day-night dip in systolic BP (SBP) of <10% has been used to characterize individuals as nondippers, and is associated with an increas ... Full text Link to item Cite

Usefulness of psychosocial treatment of mental stress-induced myocardial ischemia in men.

Journal Article Am J Cardiol · January 15, 2002 This study examined the effects of exercise and stress management training on clinical outcomes and medical expenditures over a 5-year follow-up period in 94 male patients with established coronary artery disease (CAD) and evidence of ambulatory or mental ... Full text Link to item Cite

Effects of racism and hostility on blood pressure and sodium excretion in older African Americans

Journal Article International Journal of Behavioral Medicine · 2002 Cite

Relationship of clinic, ambulatory, and laboratory stress blood pressure to left ventricular mass in overweight men and women with high blood pressure.

Journal Article Psychosom Med · 2002 Featured Publication OBJECTIVE: This study was designed to evaluate the relationship between left ventricular (LV) mass and blood pressure (BP) recorded in the following contexts: in the clinic, using standard auscultatory procedures, during a typical day using ambulatory BP m ... Full text Link to item Cite

Effects of exercise and weight loss on blood pressure during daily life.

Journal Article Med Sci Sports Exerc · October 2001 PURPOSE: The objective of this study was to investigate the effects of exercise training and weight loss on blood pressure (BP) associated with physical activity and emotional stress during daily life. METHODS: One hundred twelve participants with unmedica ... Full text Link to item Cite

Blunted nighttime blood pressure dipping in postmenopausal women.

Journal Article Am J Hypertens · August 2001 Featured Publication Blunting of the normal drop in blood pressure (BP) from day to night is emerging as a strong prognostic indicator of cardiovascular morbidity and mortality. This study evaluated the effects of natural menopause on BP dipping in African American and white w ... Full text Link to item Cite

Hormone replacement improves hemodynamic profile and left ventricular geometry in hypertensive and normotensive postmenopausal women.

Journal Article J Hypertens · February 2001 BACKGROUND: Postmenopausal estrogen replacement, with or without progestins, has been related to lower cardiovascular risks. OBJECTIVE: We investigated whether the actions of estrogen on vascular resistance contribute to this cardioprotective effect. DESIG ... Full text Link to item Cite

Depression and vascular function in older adults

Journal Article North Carolina Medical Journal · 2001 Cite

Menopause and Ethnicity affect Nighttime Blood Pressure Dipping in Women

Journal Article American Journal of Hypertension · 2001 Cite

Hemodynamic mechanisms of mental stress-induced ischemia

Journal Article PSYCHOSOMATIC MEDICINE · January 1, 2001 Link to item Cite

Religious coping, ethnicity, and ambulatory blood pressure.

Journal Article Psychosom Med · 2001 Featured Publication OBJECTIVE: To investigate the relationship between religious coping, ethnicity, and ambulatory blood pressure (ABP) measured during daily life. METHODS: A 24-hour ABP was obtained from 155 men and women (78 African American and 77 white) on a typical workd ... Full text Link to item Cite

Effects of exercise and weight loss on blood pressure during daily life

Journal Article PSYCHOSOMATIC MEDICINE · January 1, 2001 Link to item Cite

Effects of exercise and weight loss on mental stress-induced cardiovascular responses in individuals with high blood pressure.

Journal Article Hypertension · August 2000 The purpose of this study was to determine the effects of exercise and weight loss on cardiovascular responses during mental stress in mildly to moderately overweight patients with elevated blood pressure. Ninety-nine men and women with high normal or unme ... Full text Link to item Cite

Exercise and weight loss reduce blood pressure in men and women with mild hypertension: effects on cardiovascular, metabolic, and hemodynamic functioning.

Journal Article Arch Intern Med · July 10, 2000 Featured Publication BACKGROUND: Lifestyle modifications have been recommended as the initial treatment strategy for lowering high blood pressure (BP). However, evidence for the efficacy of exercise and weight loss in the management of high BP remains controversial. METHODS: O ... Full text Link to item Cite

Is there a glycemic threshold for impaired autonomic control?

Journal Article Diabetes Care · June 2000 OBJECTIVE: Although hyperglycemia has been recognized as a predictor of cardiovascular autonomic neuropathy in diabetic patients, the glucose threshold at which autonomic control begins to become impaired has not been evaluated. This study examined whether ... Full text Link to item Cite

Hemodynamic and sympathetic nervous system responses to stress during the menstrual cycle.

Journal Article AACN Clin Issues · May 2000 Featured Publication In this study, the impact of menstrual cycle phase on hemodynamic and sympathetic nervous system responses was examined during exposure to a battery of laboratory stressors. Participants were 40 healthy premenopausal women, aged 26 to 51. Impedance cardiog ... Full text Link to item Cite

Psychometric properties of the Social Phobia Inventory (SPIN). New self-rating scale.

Journal Article Br J Psychiatry · April 2000 BACKGROUND: Of available self-rated social phobia scales, none assesses the spectrum of fear, avoidance, and physiological symptoms, all of which are clinically important. Because of this limitation, we developed the Social Phobia Inventory (SPIN). AIMS: T ... Full text Link to item Cite

Emotional responsivity during daily life: relationship to psychosocial functioning and ambulatory blood pressure.

Journal Article Int J Psychophysiol · April 2000 Featured Publication Emotional responsivity refers to acute changes in affective states. This study examined the relationship of emotional responsivity during daily life with ambulatory blood pressure (ABP) and psychosocial functioning. Subjects were 162 employed men and women ... Full text Link to item Cite

Ambulatory blood pressure and marital distress in employed women.

Journal Article Behav Med · 2000 Featured Publication In this investigation, the relationship between marital distress and blood pressure during daily life in a sample of married employed women was examined. It was hypothesized that greater marital distress would be associated with elevated blood pressure in ... Full text Link to item Cite

Minority populations and psychophysiologic research: Challenges in trust building and recruitment

Journal Article Journal of Mental Health and Aging · January 1, 2000 Minority populations have been historically underrepresented in scientific research. Various factors have been cited to account for this. In this article we focus on overcoming this barrier of distrust of the medical system which can influence the particip ... Cite

Religious coping, ethnicity, and ambulatory blood pressure

Journal Article PSYCHOSOMATIC MEDICINE · January 1, 2000 Link to item Cite

Emotional responsivity and transient myocardial ischemia.

Journal Article J Consult Clin Psychol · August 1999 This study examined the relationship between "emotional responsivity" (i.e., individuals who exhibit relatively large variations of self-reported tension levels) and myocardial ischemia. One hundred thirty-six patients with coronary artery disease underwen ... Full text Link to item Cite

High stress responsivity predicts later blood pressure only in combination with positive family history and high life stress.

Journal Article Hypertension · June 1999 High cardiovascular responsivity to stressors has not consistently improved prediction of later blood pressure increases beyond the predictive effects of baseline pressure. Animal models suggest that genetic susceptibility to hypertension and frequent stre ... Full text Link to item Cite

Predicting peak oxygen uptake among older individuals with chronic stress

Journal Article Journal of Cardiopulmonary Rehabilitation · 1999 Cite

Endothelial function and cardiovascular hemodynamics during stress

Journal Article Psychosomatic Medicine · 1999 Cite

Predicting peak oxygen uptake among older patients with chronic illness.

Journal Article J Cardiopulm Rehabil · 1999 PURPOSE: To compare three equations developed to predict VO2 among patients diagnosed with one of two chronic diseases: essential hypertension (HTN), and fibromyalgia (FM). The equations included the American College of Sports Medicine (ACSM) equation, the ... Full text Link to item Cite

Endothelial function and hemodynamic responses during mental stress.

Journal Article Psychosom Med · 1999 Featured Publication OBJECTIVE: The hemodynamic basis of blood pressure responses during psychological stress shows striking individual differences that share an interesting similarity with risk for cardiovascular disease. Factors accounting for these individual differences ar ... Full text Link to item Cite

Ambulatory impedance cardiography: a feasibility study.

Journal Article J Appl Physiol (1985) · December 1998 Featured Publication A wearable, ambulatory impedance monitor (AIM) has been developed to permit impedance cardiographic measurements while patients and volunteers engage in normal daily activities. The AIM system was developed for use with a new hybrid tetrapolar spot-band el ... Full text Link to item Cite

Psychosocial influences on blood pressure during daily life.

Journal Article Int J Psychophysiol · March 1998 Featured Publication Ambulatory blood pressure (ABP) monitoring allows frequent non-invasive blood pressure (BP) recordings in a variety of settings. Emerging evidence suggests that ABP is a better predictor of cardiovascular morbidity than clinic BP. Ambulatory blood pressure ... Full text Link to item Cite

Hostility and adrenergic receptor responsiveness: evidence of reduced beta-receptor responsiveness in high hostile men.

Journal Article J Psychosom Res · February 1998 We examined the relation of Cook and Medley Hostility (Ho) scores to alpha- and beta-adrenergic receptor responsiveness to pharmacological agonists in 22 normotensive and 14 hypertensives (aged 18-34) white males, matched for age and body mass. alpha-Adren ... Full text Link to item Cite

High anxiety and white coat hypertension.

Journal Article JAMA · January 21, 1998 Featured Publication Full text Link to item Cite

Anxiety and vagal control of heart rate.

Journal Article Psychosom Med · 1998 OBJECTIVE: Prospective studies have demonstrated that anxiety predicts sudden cardiac death, but the mechanism underlying this increased risk is unclear. This study examined whether anxiety is associated with reductions in vagal control of heart rate in he ... Full text Link to item Cite

Ambulatory Impedance Cardiography: Evaluation of a new instrument

Journal Article Journal of Applied Physiology · 1998 Cite

Blood pressure reactivity and marital distress in employed women.

Journal Article Psychosom Med · 1998 Featured Publication OBJECTIVE: The impact of marital distress on cardiovascular responses to an "ecologically valid" laboratory stressor (a marital conflict recall task) was examined in maritally distressed and non-distressed women. It was hypothesized that the presence of hi ... Full text Link to item Cite

Effect of satisfaction with social support on blood pressure in normotensive and borderline hypertensive men and women.

Journal Article Int J Behav Med · 1998 The relation between blood pressure (BP) and two aspects of social support, perceived satisfaction and structural social support network characteristics, were examined in adults classified as having normal BP or borderline hypertension. Causal BPs were tak ... Full text Link to item Cite

NEUROENDOCRINE FACTORS IN PREMENSTRUAL DYSPHORIC DISORDER

Journal Article Psychosomatic Medicine · 1998 Full text Cite

Ten-year stability of cardiovascular responses to laboratory stressors.

Journal Article Psychophysiology · March 1997 Featured Publication In this study, we examined test-retest stability of cardiovascular stress responses over a decade of the life span. Participants were 55 male college undergraduates, 19 years of age at initial testing, and 29 years of age at follow-up testing. Stressors we ... Full text Link to item Cite

Noninvasive assessment of baroreflex control in borderline hypertension. Comparison with the phenylephrine method.

Journal Article Hypertension · August 1996 In this study, we examined the sensitivity of two recently developed noninvasive baroreflex measurement techniques to assess baroreflex control in hypertension. We assessed baroreflex sensitivity noninvasively from covariations of systolic pressure and RR ... Full text Link to item Cite

Ethnic differences in forearm vasodilator capacity.

Journal Article Am J Cardiol · July 15, 1996 Previous studies have demonstrated significant ethnic differences in left ventricular structure in both normotensive and hypertensive subjects. To determine if these differences in ventricular geometry are associated with differences in vascular structure, ... Full text Link to item Cite

Blood pressure responses to stress: Relation to left ventricular structure and function.

Journal Article Ann Behav Med · March 1996 The relations of resting blood pressure, blood pressure during standardized stressors, and workplace blood pressure to left ventricular structure and diastoKc filling were evaluated in 133 healthy young adults (mean age = 30 + 7 years) without hypertension ... Full text Link to item Cite

The ability of active versus passive coping tasks to predict future blood pressure levels in normotensive men and women.

Journal Article Int J Behav Med · 1996 Casual blood pressure (BP) after a 2-year follow-up interval was determined in 40 normotensive men and women (20 Blacks and 20 Whites), who had been initially tested for cardiovascular responses to a variety of active and passive coping tasks, including ac ... Full text Link to item Cite

Ethnic differences in hemodynamic responses to stress in hypertensive men and women.

Journal Article Am J Hypertens · June 1995 Featured Publication Hemodynamic response patterns to three laboratory stressors were compared in 63 mildly hypertensive black and white men and women. Ethnic groups were matched for age, body mass index, and casual blood pressures. Stressors included a mental arithmetic task, ... Full text Link to item Cite

Job status and high-effort coping influence work blood pressure in women and blacks.

Journal Article Hypertension · April 1995 Work-related stress has been associated with an increased risk of hypertension and more severe cardiovascular problems in white men but has been less studied in women and black men. To determine whether the trait of high-effort coping (John Henryism) was r ... Full text Link to item Cite

Physiological determinants of hyperreactivity to stress in borderline hypertension.

Journal Article Hypertension · March 1995 Featured Publication Blood pressure hyperreactivity during stress is characteristic of borderline hypertension in white men. The present study evaluated the hemodynamic basis of this hyperreactivity and assessed its physiological basis in terms of sympathetic nervous system fu ... Full text Link to item Cite

Do exercise and weight loss reduce blood pressure in patients with mild hypertension?

Journal Article N C Med J · February 1995 We conclude from our review that exercise and weight loss offer some promise as non-pharmacologic treatments for hypertension. Unfortunately, most available studies are methodologically unsound, and the mechanisms by which exercise lowers blood pressure ar ... Link to item Cite

Ethnic differences in hemodynamic responses to stress in hypertensive men and women

Journal Article American Journal of Hypertension · 1995 Cite

Family history of hypertension and cardiovascular response to stress in black and white males

Journal Article International Journal of Behavioral Medicine · 1995 Cite

Parental history of hypertension and cardiovascular response to stress in Black and White men.

Journal Article Int J Behav Med · 1995 White offspring of hypertensives typically exhibit an elevated cardiovascular response to stress. Studies of Black offspring of hypertensives have been fewer, with inconsistent results. This may be due, in part. to incomplete characterizations of hemodynam ... Full text Link to item Cite

Hemodynamic responses during psychological stress: implications for studying disease processes.

Journal Article Int J Behav Med · 1995 Featured Publication Investigation of the physiological correlates of psychological stress is of interest in relation to the putative impact of stress in the etiology of cardiovascular disease. Although the assessment of blood pressure and heart rate responses to psychological ... Full text Link to item Cite

Intertask consistency of hemodynamic responses to laboratory stressors in a biracial sample of men and women.

Journal Article Int J Psychophysiol · July 1994 Cardiovascular responses were examined in a community sample of 128 subjects, comprised of 58 African American and 70 Caucasian American men and women. Subjects completed a battery of laboratory stressors including mental arithmetic, reaction time, a speec ... Full text Link to item Cite

Comparison of cardiac versus vascular reactors and ethnic groups in plasma epinephrine and norepinephrine responses to stress.

Journal Article Int J Behav Med · 1994 This study examined differences in plasma epinephrine (EPI) and norepinephrine (NOREPI) responses to stressors in 67 healthy African-American and Caucasian American men and women of the ages 18 to 49. Subjects were divided into three groups: (a) those who ... Full text Link to item Cite

Mechanisms underlying cardiovascular defense reaction evoked by dorsal periaqueductal gray stimulation.

Journal Article Am J Physiol · November 1993 Hemodynamic and autonomic mechanisms underlying the cardiovascular defense reaction elicited by electrical stimulation of the dorsolateral periaqueductal gray region were evaluated in pentobarbital sodium-anesthetized Sprague-Dawley rats. Stimulation of th ... Full text Link to item Cite

Race and gender comparisons: I. Hemodynamic responses to a series of stressors.

Journal Article Health Psychol · September 1993 A sample of 155 adults, age 18-49 years, including nearly equal subgroups of Black and White men and women, underwent evaluation of cardiovascular reactivity during 5 behavioral stressors. Among the men, overall blood pressure increases to tasks did not di ... Full text Link to item Cite

Race and gender comparisons: II. Predictions of work blood pressure from laboratory baseline and cardiovascular reactivity measures.

Journal Article Health Psychol · September 1993 In 148 Black and White men and women, laboratory measures of blood pressure (BP), heart rate, stroke volume (SV), cardiac output (CO) and total peripheral resistance (TPR) during baseline and 5 stressors were examined in relationship to ambulatory systolic ... Full text Link to item Cite

Responsiveness to alpha- and beta-adrenergic receptor agonists. Effects of race in borderline hypertensive compared to normotensive men.

Journal Article Am J Hypertens · July 1993 The responsiveness of alpha- and beta-adrenergic receptors was assessed in 13 black and 13 white borderline hypertensive and normotensive men, matched for age and body mass. White borderline hypertensives showed significantly decreased responsiveness of ca ... Full text Link to item Cite

Postural stability of hemodynamic responses during mental challenge.

Journal Article Psychophysiology · May 1993 Laboratory stress testing is typically conducted while subjects are seated, whereas real-life stressors may often be encountered while standing. The present study of 20 healthy young men evaluated blood pressure and underlying hemodynamic adjustments to a ... Full text Link to item Cite

Laboratory reactivity assessment: effects of casual blood pressure status and choice of task difficulty.

Journal Article Int J Psychophysiol · January 1993 In a study of 60 healthy young men, 26 with high and 34 with normal casual systolic pressure, blood pressure and its underlying hemodynamic determinants were measured at rest and during exposure to a series of laboratory tasks. Subjects were given a choice ... Full text Link to item Cite

Mechanisms underlying cardiovascular defense reaction evoked by dorsal periaqueductal gray stimulation

Journal Article American Journal of Physiology - Regulatory Integrative and Comparative Physiology · January 1, 1993 Hemodynamic and autonomic mechanisms underlying the cardiovascular defense reaction elicited by electrical stimulation of the dorsolateral periaqueductal gray region were evaluated in pentobarbital sodium- anesthetized Sprague-Dawley rats. Stimulation of t ... Cite

Responsiveness to α- and β-adrenergic receptor agonists. Effects of race in borderline hypertensive compared to normotensive men

Journal Article American Journal of Hypertension · 1993 The responsiveness of α- and β-adrenergic receptors was assessed in 13 black and 13 white border-line hypertensive and normotensive men, matched for age and body mass. White borderline hypertensives showed significantly decreased responsiveness of cardiac ... Cite

Comparison of impedance cardiographic measurements using band and spot electrodes.

Journal Article Psychophysiology · November 1992 Featured Publication The comprehensive assessment of cardiac function using impedance cardiography has led to increasingly widespread use of the technique in psychophysiology. Disposable adhesive band electrodes have been the most widely used electrode type, but spot electrode ... Full text Link to item Cite

Cognitive coping strategies and blood pressure responses to real-life stress in healthy young men.

Journal Article Health Psychol · 1992 Coping style is an important feature in the understanding of the relation between real-life stress and associated blood pressure (BP) responses. In this study, 10 high- and 10 low-"self-focused-coping" (SFC) male college students were tested with ambulator ... Full text Link to item Cite

Cardiovascular reactivity assessment: effects of choice of difficulty on laboratory task responses.

Journal Article Int J Psychophysiol · January 1992 Featured Publication This laboratory study of cardiovascular reactivity was designed to examine how a choice of difficulty element in a mental arithmetic task would affect cardiovascular responses. 20 healthy male subjects were tested on a computer-controlled mental arithmetic ... Full text Link to item Cite

Cardiovascular responses to an active coping challenge as predictors of blood pressure patterns 10 to 15 years later.

Journal Article Psychosom Med · 1992 To assess the long-term predictive importance of high cardiovascular reactivity in relation to subsequent blood pressure, 51 men from a pool of 204 men originally tested at age 18 to 22 years were recruited for blood pressure assessment 10 to 15 years late ... Full text Link to item Cite

Comparison of spot and band electrodes for monitoring cardiac performance by impedance cardiography during exercise

Journal Article Proceedings of the Annual Conference on Engineering in Medicine and Biology · December 1, 1991 A comfortable and convenient electrode configuration using disposable ECG electrodes for recording the impedance cardiogram was compared to the traditional band electrodes. Measurement of systolic time intervals at rest and during exercise was unaffected b ... Cite

Hemodynamic response patterns during mental stress

Journal Article Proceedings of the Annual Conference on Engineering in Medicine and Biology · December 1, 1991 Individuals may differ markedly in the relative contribution of cardiac output and vascular resistance changes responsible for the blood pressure increases they exhibit. Evidence is presented showing that these hemodynamic response patterns appear to be st ... Cite

Generalization of cardiovascular response: supportive evidence for the reactivity hypothesis.

Journal Article Int J Psychophysiol · August 1991 Cardiovascular responses were monitored while 36 subjects completed a battery of laboratory stressors comprising mental arithmetic, a reaction time task, a speech task, and the forehead cold pressor. Inter-task consistency was assessed for each of 6 physio ... Full text Link to item Cite

Cardiovascular responses to weighing in healthy subjects.

Journal Article J Cardiovasc Nurs · July 1991 This study examined the cardiovascular responses of 22 healthy subjects (mean age 48 years) to two methods of weighing--over bed and standing scale. Variables were measured at one-minute intervals during the weighing treatments and a rest period after each ... Full text Link to item Cite

Cardiac output by impedance cardiography: two alternative methodologies compared with thermodilution.

Journal Article Aviat Space Environ Med · February 1991 Featured Publication One critical component of the Kubicek (8) stroke volume equation, used to measure cardiac output by impedance cardiography, is dZ/dt(max). The present study, conducted on six anesthetized dogs, compared impedance cardiac output derived using two alternativ ... Link to item Cite

Postural effects on blood pressure reactivity: implications for studies of laboratory-field generalization.

Journal Article J Psychosom Res · 1991 This study was designed as an in-laboratory evaluation of the significance of postural blood pressure (BP) adjustments in the investigation of laboratory-field generalization. Blood pressure responses were monitored while 20 subjects completed a mental ari ... Full text Link to item Cite

Hemodynamics of blood pressure responses during active and passive coping.

Journal Article Psychophysiology · November 1990 Featured Publication This laboratory study was designed to address a number of interrelated issues regarding cardiovascular reactivity to psychological stress. One objective was to extend the previous research comparing cardiovascular responses during active versus passive cop ... Full text Link to item Cite

Temporal stability of the hemodynamics of cardiovascular reactivity.

Journal Article Int J Psychophysiol · November 1990 Cardiovascular responses to a competitive reaction-time task were monitored in 13 male subjects tested twice, 3 months apart. The temporal stability of blood pressure responses was in line with previous reports. However, in this study impedance cardiograph ... Full text Link to item Cite

Methodological guidelines for impedance cardiography.

Journal Article Psychophysiology · January 1990 Featured Publication Impedance cardiography was introduced over 20 years ago as a noninvasive and unobtrusive technique for measuring systolic time intervals and cardiac output. Although our understanding of the physiological events reflected in the impedance cardiogram has be ... Full text Link to item Cite

Gender differences in blood pressure control during a variety of behavioral stressors.

Journal Article Psychosom Med · 1990 This study assessed gender differences in hemodynamic response patterns to behavioral stressors. In addition, the extent to which gender differences in cardiovascular reactivity were a function of the type of challenge was determined by employing tasks rel ... Full text Link to item Cite

Cardiovascular responses to behavioral stressors: laboratory-field generalization and inter-task consistency.

Journal Article J Psychosom Res · 1990 Blood pressure and heart rate responses were monitored while 30 medical, dental or graduate students completed four laboratory tasks. On a second day, subjects wore an ambulatory blood pressure monitor, and during this day they completed the real-world cha ... Full text Link to item Cite

Race, borderline hypertension, and hemodynamic responses to behavioral stress before and after beta-adrenergic blockade.

Journal Article Health Psychol · 1989 Blood pressure (BP) and hemodynamic responses (cardiac output [CO] and total peripheral resistance [TPR]) to a competitive reaction-time task, previously shown to increase beta-adrenergic activity, were compared in 20 Black and 20 White young men, once fol ... Full text Link to item Cite

Effects of aerobic exercise training on hemodynamic responses during psychosocial stress in normotensive and borderline hypertensive type A men: a preliminary report.

Journal Article Psychosom Med · 1989 This study assessed the effects of aerobic exercise training on cardiovascular responses to a 5-min reaction time competition task. Twenty-seven Type A men (aged 30-56) participated in this randomized study in which 14 underwent supervised aerobic training ... Full text Link to item Cite

Cardiovascular responses in the laboratory and in the natural environment: is blood pressure reactivity to laboratory-induced mental stress related to ambulatory blood pressure during everyday life?

Journal Article J Psychosom Res · 1989 Cardiovascular activity recorded at rest and during mental stress in the laboratory was studied in relation to ambulatory recorded cardiovascular activity at work and at home. Fifty-five Type A men (M = 42.4 years) underwent a standardized laboratory menta ... Full text Link to item Cite

Motor preparation aspects of cardiovascular reactivity to psychological challenge.

Journal Article Int J Psychophysiol · November 1988 Featured Publication Neural control of the circulation has evolved in such a way that behavioral responses to psychological stress may be accompanied by a dramatic activation of the cardiovascular system. This study was designed to address the hypothesis that such instances of ... Full text Link to item Cite

Effects of race and marginally elevated blood pressure on responses to stress.

Journal Article Hypertension · December 1987 A total of 228 men, aged 18 to 22 years (109 black and 119 white), underwent monitoring of heart rate (HR) and systolic (SBP) and diastolic blood pressure (DBP) responses during several stressor conditions and a 30-minute posttask rest period. Stressors in ... Full text Link to item Cite

Stability of cardiovascular reactivity to laboratory stressors: a 2 1/2 yr follow-up.

Journal Article J Psychosom Res · 1987 The temporal stability of cardiovascular reactivity to laboratory stressors over a 2 1/2 yr period was studied. Subjects who had earlier received a cold pressor and a shock avoidance reaction time task were brought back for retesting using almost identical ... Full text Link to item Cite

Aedes albopictus cells resistant to adenosine because of a defect in nucleoside transport.

Journal Article Somatic Cell Genet · September 1982 By growing Aedes albopictus mosquito cells in media containing increasing concentrations of adenosine and subsequently plating low numbers of cells in the presence of EHNA (an inhibitor of adenosine deaminase), three clones were obtained which were resista ... Full text Link to item Cite

A simple preparation for obtaining a reliable heart rate record in freely moving rats

Journal Article Behavior Research Methods & Instrumentation · November 1, 1981 A technique for recording heart rate (HR) from freely moving rats using a specially developed harness and subdermal electrodes is described. Electrodes are implanted via a hypodermic needle. Animals prepared in this way are unrestricted in their behavior a ... Full text Cite