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Ann Julia Brown

Senior Associate Dean of the School of Medicine
School of Medicine
Duke Box 3611, Durham, NC 27710
268 Baker House, Durham, NC 27710

Selected Publications


Scoping Review of Restorative Justice in Academics and Medicine: A Powerful Tool for Justice Equity Diversity and Inclusion.

Journal Article Health Equity · 2023 PURPOSE: Restorative Justice (RJ) as a practice and mindset is growing within academic medicine and health care. The authors aim to categorize the extent to which RJ training and practices have been researched, explored, and applied within health care, med ... Full text Open Access Link to item Cite

From Stigma to Validation: A Qualitative Assessment of a Novel National Program to Improve Retention of Physician-Scientists with Caregiving Responsibilities.

Journal Article J Womens Health (Larchmt) · December 2020 Background: Research is needed to improve understanding of work-life integration issues in academic medicine and to guide the implementation of the Doris Duke Charitable Foundation's Fund to Retain Clinical Scientists (FRCS), a national initiative offering ... Full text Link to item Cite

The Most Valuable Resource Is Time: Insights From a Novel National Program to Improve Retention of Physician-Scientists With Caregiving Responsibilities.

Journal Article Acad Med · November 2019 PURPOSE: To enhance understanding of challenges related to work-life integration in academic medicine and to inform the ongoing implementation of an existing program and the development of other interventions to promote success of physician-scientists. MET ... Full text Link to item Cite

Multidisciplinary Mentoring Programs to Enhance Junior Faculty Research Grant Success.

Journal Article Acad Med · October 2017 PROBLEM: Junior faculty face challenges in establishing independent research careers. Declining funding combined with a shift to multidisciplinary, collaborative science necessitates new mentorship models and enhanced institutional support. APPROACH: Two m ... Full text Link to item Cite

Secondary amenorrhea: Diagnostic approach and treatment considerations.

Journal Article Nurse Pract · September 21, 2017 Disruptions in the menstrual cycle are a common complaint in primary care and women's health. Irregular or absent menstrual periods should trigger an evaluation to identify the root cause. This article discusses secondary amenorrhea and provides a systemat ... Full text Link to item Cite

Screening for glucose intolerance in polycystic ovary syndrome: hemoglobin A1C, fasting blood glucose or oral glucose tolerance test?

Journal Article Expert Rev Endocrinol Metab · November 2014 Polycystic ovary syndrome (PCOS) is a chronic condition with many reproductive, metabolic and psychological manifestations. Insulin resistance puts women with PCOS at an increased risk for developing impaired glucose tolerance (IGT) and diabetes (T2D). An ... Full text Link to item Cite

Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome.

Journal Article World J Gastroenterol · October 21, 2014 Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-aged women. Women with PCOS frequently have metabolic complications including insulin resistance (IR), early diabetes, hypertension and dyslipidemia. Recent studies have ... Full text Link to item Cite

Polycystic ovary syndrome: update on diagnosis and treatment.

Journal Article Am J Med · October 2014 Polycystic ovary syndrome is now a well-recognized condition affecting 6%-25% of reproductive-aged women, depending on the definition. Over the past 3 decades, research has launched it from relative medical obscurity to a condition increasingly recognized ... Full text Link to item Cite

The ophthalmologist of the future.

Journal Article Arch Ophthalmol · September 2012 Who are the ophthalmologists of the future? How will the new generation practice? How will they interact with their professional organizations? What part will technology play in their lives and professions? A new paradigm is in place that will dramatically ... Full text Link to item Cite

Higher high-density lipoprotein cholesterol in African-American women with polycystic ovary syndrome compared with Caucasian counterparts.

Journal Article J Clin Endocrinol Metab · September 2010 CONTEXT: Studies have demonstrated lipid differences among African-Americans and Caucasians and between women with polycystic ovary syndrome (PCOS) and normally ovulating women. However, few studies have examined racial differences in lipoprotein levels in ... Full text Link to item Cite

Effects of exercise on lipoprotein particles in women with polycystic ovary syndrome.

Journal Article Med Sci Sports Exerc · March 2009 PURPOSE: Women with polycystic ovary syndrome (PCOS) commonly have insulin resistance. Insulin resistance is associated with marked abnormalities of lipoprotein size and subclass particle concentration. The purpose of this study was to examine the effects ... Full text Link to item Cite

Can individuals meet multiple physical activity and dietary behavior goals?

Journal Article Am J Health Behav · 2009 OBJECTIVES: To examine whether participants with the most behavioral goals to achieve were more likely to meet more goals than those given fewer goals. METHODS: Eight hundred ten participants were randomly assigned to advice-only, established guidelines fo ... Full text Link to item Cite

Postpartum Thyroiditis: Not Just a Worn Out Mom

Journal Article Journal for Nurse Practitioners · January 1, 2008 Postpartum thyroiditis (PPT) is a common condition that can occur in the first 12 months after delivery, affecting 5% to 7% of all postpartum women. This article provides a case illustration of this disorder. The typical clinical course for PPT is that of ... Full text Cite

Challenges and opportunities for recruiting a new generation of neurosurgeons.

Journal Article Neurosurgery · December 2007 Several factors have converged to raise concern among program directors about attracting and training the next generation of neurosurgeons. These include the relatively new duty-hour regulations, the projected physician shortage, and the preference of many ... Full text Link to item Cite

Health needs and barriers to healthcare of women who have experienced intimate partner violence.

Journal Article J Womens Health (Larchmt) · December 2007 BACKGROUND: This study assessed the health needs and barriers to healthcare among women with a history of intimate partner violence (IPV) as told by women themselves. METHODS: Qualitative interviews were conducted with 25 women clients and 10 staff members ... Full text Link to item Cite

Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome.

Journal Article Hypertension · October 2007 Featured Publication Lifestyle modification can reduce blood pressure and lower cardiovascular risk. Established recommendations include weight loss, sodium reduction, and increased physical activity. PREMIER studied the effects of lifestyle interventions based on established ... Full text Link to item Cite

Access and diversity in academic mentoring.

Journal Article JAMA · August 15, 2007 Featured Publication Full text Link to item Cite

Comprehensive clinical management of polycystic ovary syndrome.

Journal Article Minerva Med · June 2007 Featured Publication Polycystic ovary syndrome (PCOS) affects 6-7% of reproductive-aged women. Although the diagnostic criteria for PCOS have been debated, it is frequently characterized by hyperandrogenism (hirsutism, acne, male-pattern hair loss), oligo-anovulation, and poly ... Link to item Cite

Scoping Review of Restorative Justice in Academics and Medicine: A Powerful Tool for Justice Equity Diversity and Inclusion.

Journal Article Health Equity · 2023 PURPOSE: Restorative Justice (RJ) as a practice and mindset is growing within academic medicine and health care. The authors aim to categorize the extent to which RJ training and practices have been researched, explored, and applied within health care, med ... Full text Open Access Link to item Cite

From Stigma to Validation: A Qualitative Assessment of a Novel National Program to Improve Retention of Physician-Scientists with Caregiving Responsibilities.

Journal Article J Womens Health (Larchmt) · December 2020 Background: Research is needed to improve understanding of work-life integration issues in academic medicine and to guide the implementation of the Doris Duke Charitable Foundation's Fund to Retain Clinical Scientists (FRCS), a national initiative offering ... Full text Link to item Cite

The Most Valuable Resource Is Time: Insights From a Novel National Program to Improve Retention of Physician-Scientists With Caregiving Responsibilities.

Journal Article Acad Med · November 2019 PURPOSE: To enhance understanding of challenges related to work-life integration in academic medicine and to inform the ongoing implementation of an existing program and the development of other interventions to promote success of physician-scientists. MET ... Full text Link to item Cite

Multidisciplinary Mentoring Programs to Enhance Junior Faculty Research Grant Success.

Journal Article Acad Med · October 2017 PROBLEM: Junior faculty face challenges in establishing independent research careers. Declining funding combined with a shift to multidisciplinary, collaborative science necessitates new mentorship models and enhanced institutional support. APPROACH: Two m ... Full text Link to item Cite

Secondary amenorrhea: Diagnostic approach and treatment considerations.

Journal Article Nurse Pract · September 21, 2017 Disruptions in the menstrual cycle are a common complaint in primary care and women's health. Irregular or absent menstrual periods should trigger an evaluation to identify the root cause. This article discusses secondary amenorrhea and provides a systemat ... Full text Link to item Cite

Screening for glucose intolerance in polycystic ovary syndrome: hemoglobin A1C, fasting blood glucose or oral glucose tolerance test?

Journal Article Expert Rev Endocrinol Metab · November 2014 Polycystic ovary syndrome (PCOS) is a chronic condition with many reproductive, metabolic and psychological manifestations. Insulin resistance puts women with PCOS at an increased risk for developing impaired glucose tolerance (IGT) and diabetes (T2D). An ... Full text Link to item Cite

Review of nonalcoholic fatty liver disease in women with polycystic ovary syndrome.

Journal Article World J Gastroenterol · October 21, 2014 Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-aged women. Women with PCOS frequently have metabolic complications including insulin resistance (IR), early diabetes, hypertension and dyslipidemia. Recent studies have ... Full text Link to item Cite

Polycystic ovary syndrome: update on diagnosis and treatment.

Journal Article Am J Med · October 2014 Polycystic ovary syndrome is now a well-recognized condition affecting 6%-25% of reproductive-aged women, depending on the definition. Over the past 3 decades, research has launched it from relative medical obscurity to a condition increasingly recognized ... Full text Link to item Cite

The ophthalmologist of the future.

Journal Article Arch Ophthalmol · September 2012 Who are the ophthalmologists of the future? How will the new generation practice? How will they interact with their professional organizations? What part will technology play in their lives and professions? A new paradigm is in place that will dramatically ... Full text Link to item Cite

Higher high-density lipoprotein cholesterol in African-American women with polycystic ovary syndrome compared with Caucasian counterparts.

Journal Article J Clin Endocrinol Metab · September 2010 CONTEXT: Studies have demonstrated lipid differences among African-Americans and Caucasians and between women with polycystic ovary syndrome (PCOS) and normally ovulating women. However, few studies have examined racial differences in lipoprotein levels in ... Full text Link to item Cite

Effects of exercise on lipoprotein particles in women with polycystic ovary syndrome.

Journal Article Med Sci Sports Exerc · March 2009 PURPOSE: Women with polycystic ovary syndrome (PCOS) commonly have insulin resistance. Insulin resistance is associated with marked abnormalities of lipoprotein size and subclass particle concentration. The purpose of this study was to examine the effects ... Full text Link to item Cite

Can individuals meet multiple physical activity and dietary behavior goals?

Journal Article Am J Health Behav · 2009 OBJECTIVES: To examine whether participants with the most behavioral goals to achieve were more likely to meet more goals than those given fewer goals. METHODS: Eight hundred ten participants were randomly assigned to advice-only, established guidelines fo ... Full text Link to item Cite

Postpartum Thyroiditis: Not Just a Worn Out Mom

Journal Article Journal for Nurse Practitioners · January 1, 2008 Postpartum thyroiditis (PPT) is a common condition that can occur in the first 12 months after delivery, affecting 5% to 7% of all postpartum women. This article provides a case illustration of this disorder. The typical clinical course for PPT is that of ... Full text Cite

Challenges and opportunities for recruiting a new generation of neurosurgeons.

Journal Article Neurosurgery · December 2007 Several factors have converged to raise concern among program directors about attracting and training the next generation of neurosurgeons. These include the relatively new duty-hour regulations, the projected physician shortage, and the preference of many ... Full text Link to item Cite

Health needs and barriers to healthcare of women who have experienced intimate partner violence.

Journal Article J Womens Health (Larchmt) · December 2007 BACKGROUND: This study assessed the health needs and barriers to healthcare among women with a history of intimate partner violence (IPV) as told by women themselves. METHODS: Qualitative interviews were conducted with 25 women clients and 10 staff members ... Full text Link to item Cite

Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome.

Journal Article Hypertension · October 2007 Featured Publication Lifestyle modification can reduce blood pressure and lower cardiovascular risk. Established recommendations include weight loss, sodium reduction, and increased physical activity. PREMIER studied the effects of lifestyle interventions based on established ... Full text Link to item Cite

Access and diversity in academic mentoring.

Journal Article JAMA · August 15, 2007 Featured Publication Full text Link to item Cite

Comprehensive clinical management of polycystic ovary syndrome.

Journal Article Minerva Med · June 2007 Featured Publication Polycystic ovary syndrome (PCOS) affects 6-7% of reproductive-aged women. Although the diagnostic criteria for PCOS have been debated, it is frequently characterized by hyperandrogenism (hirsutism, acne, male-pattern hair loss), oligo-anovulation, and poly ... Link to item Cite

Sexual dysfunction in women with polycystic ovary syndrome: The effects of testosterone, obesity, and depression

Journal Article Journal of Pelvic Medicine and Surgery · May 1, 2007 OBJECTIVES: We examine the relationship among sexual function, obesity, psychologic depression, and serum total (totT) and bioavailable (bioT) testosterone levels in a group of premenopausal women with polycystic ovary syndrome (PCOS). METHODS: Women with ... Full text Cite

Polycystic ovary syndrome: diagnosis and treatment.

Journal Article Am J Med · February 2007 Featured Publication Polycystic ovary syndrome affects 6%-7% of reproductive-aged women, making it the most common endocrine disorder in this population. It is characterized by chronic anovulation and hyperandrogenism. Affected women may present with reproductive manifestation ... Full text Link to item Cite

The Effect of Flaxseed Supplementation on Hormonal Levels Associated with Polycystic Ovarian Syndrome: A Case Study.

Journal Article Curr Top Nutraceutical Res · 2007 Flaxseed is a rich source of lignan and has been shown to reduce androgen levels in men with prostate cancer. Polycystic ovarian syndrome (PCOS), a common endocrine disorder among women in their reproductive years, also is associated with high levels of an ... Link to item Cite

Nonalcoholic steatohepatitis and nonalcoholic Fatty liver disease in young women with polycystic ovary syndrome.

Journal Article J Clin Endocrinol Metab · May 2006 Featured Publication CONTEXT: Nonalcoholic fatty liver disease and polycystic ovary syndrome (PCOS) are both associated with insulin resistance. Thus, women with PCOS may have an increased prevalence of nonalcoholic fatty liver disease, including nonalcoholic steatohepatitis ( ... Full text Link to item Cite

Visual vignette

Journal Article Endocrine Practice · May 1, 2006 Cite

Number of children and risk of metabolic syndrome in women.

Journal Article J Womens Health (Larchmt) · 2006 Featured Publication BACKGROUND: In the United States, there is a high prevalence of metabolic syndrome, as defined by The Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP I ... Full text Link to item Cite

Diagnosis of mosaic Turner's syndrome in a middle-aged woman.

Journal Article Endocr Pract · 2006 Featured Publication Full text Link to item Cite

Visual vignette. Pituitary apoplexy.

Journal Article Endocr Pract · 2006 Featured Publication Full text Link to item Cite

Generation X: implications for faculty recruitment and development in academic health centers.

Journal Article Acad Med · March 2005 Featured Publication Differences and tensions between the Baby Boom generation (born 1945-1962) and Generation X (born 1963-1981) have profound implications for the future of academic medicine. By and large, department heads and senior faculty are Boomers; today's residents an ... Full text Link to item Cite

Polycystic ovary syndrome and severe nonalcoholic steatohepatitis: beneficial effect of modest weight loss and exercise on liver biopsy findings.

Journal Article Endocr Pract · 2005 Featured Publication OBJECTIVE: To report a case of biopsy-documented nonalcoholic steatohepatitis (NASH), which improved appreciably through moderate exercise and weight loss in a young woman with polycystic ovary syndrome (PCOS) and insulin resistance. METHODS: We present a ... Full text Link to item Cite

Gestational diabetes mellitus

Journal Article Clinical Diabetes · January 1, 2005 Full text Cite

Depression and insulin resistance: applications to polycystic ovary syndrome.

Journal Article Clin Obstet Gynecol · September 2004 Featured Publication Full text Link to item Cite

Women in academic medicine: a report of focus groups and questionnaires, with conjoint analysis.

Journal Article J Womens Health (Larchmt) · December 2003 Featured Publication BACKGROUND: The percentage of women graduating from U.S. medical schools has increased dramatically over the past 30 years, but the distribution of women and men across faculty ranks in academic medical centers has remained nearly unchanged. Women remain u ... Full text Link to item Cite

Strategies for building a multidisciplinary academic program in women's health.

Journal Article J Womens Health Gend Based Med · September 1999 Featured Publication During the decade of the 1990s, women's health has received unprecedented attention from government, industry, marketers of healthcare, and academic medical centers. An assessment of research, education, and healthcare delivery has exposed gaps in our know ... Full text Link to item Cite

Efficacy and safety of acarbose in metformin-treated patients with type 2 diabetes.

Journal Article Diabetes Care · December 1998 OBJECTIVE: To demonstrate the efficacy, tolerability, and safety of acarbose compared with placebo in patients with type 2 diabetes inadequately controlled with diet and metformin (2,000 or 2,500 mg/day in divided doses). RESEARCH DESIGN AND METHODS: This ... Full text Link to item Cite

For patients: hormone replacement therapy.

Journal Article N C Med J · 1997 Featured Publication Link to item Cite