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April Deveaux

Medical Instructor in Population Health Sciences
Population Health Sciences
200 Morris St., Durham, NC 27710

Selected Publications

Racial Differences in Vaginal Fluid Metabolites and Association with Systemic Inflammation Markers among Ovarian Cancer Patients: A Pilot Study.

Journal Article Cancers (Basel) · March 23, 2024 The vaginal microbiome differs by race and contributes to inflammation by directly producing or consuming metabolites or by indirectly inducing host immune response, but its potential contributions to ovarian cancer (OC) disparities remain unclear. In this ... Full text Link to item Cite

Association of reproductive risk factors and breast cancer molecular subtypes: a systematic review and meta-analysis.

Journal Article BMC Cancer · July 10, 2023 BACKGROUND: Associations between reproductive factors and breast cancer (BC) risk vary by molecular subtype (i.e., luminal A, luminal B, HER2, and triple negative/basal-like [TNBC]). In this systematic review and meta-analysis, we summarized the associatio ... Full text Link to item Cite

Development and Psychometric Evaluation of Healthcare Access Measures among Women with Ovarian Cancer.

Journal Article Cancers (Basel) · December 19, 2022 Several proposed theoretical frameworks have defined the complex nature of healthcare access (HCA) [...]. ... Full text Link to item Cite

Associations of Healthcare Affordability, Availability, and Accessibility with Quality Treatment Metrics in Patients with Ovarian Cancer.

Journal Article Cancer Epidemiol Biomarkers Prev · July 1, 2022 BACKGROUND: Differential access to quality care is associated with racial disparities in ovarian cancer survival. Few studies have examined the association of multiple healthcare access (HCA) dimensions with racial disparities in quality treatment metrics, ... Full text Link to item Cite

Association of lipid profile biomarkers with breast cancer by molecular subtype: analysis of the MEND study.

Journal Article Sci Rep · June 23, 2022 There is conflicting evidence on the role of lipid biomarkers in breast cancer (BC), and no study to our knowledge has examined this association among African women. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for the association o ... Full text Link to item Cite

Metabolic Syndrome and Risk of Breast Cancer by Molecular Subtype: Analysis of the MEND Study.

Journal Article Clin Breast Cancer · June 2022 BACKGROUND: Metabolic syndrome (MetS) is characterized by a cluster of biological irregularities. The purpose of this analysis was to examine the association of MetS with BC among Nigerian women, and for the first time evaluate this association by molecula ... Full text Link to item Cite

Ovarian Cancer Epidemiology, Healthcare Access and Disparities (ORCHiD): methodology for a population-based study of black, Hispanic and white patients with ovarian cancer.

Journal Article BMJ Open · October 4, 2021 INTRODUCTION: Less than 40% of patients with ovarian cancer (OC) in the USA receive stage-appropriate guideline-adherent surgery and chemotherapy. Black patients with cancer report greater depression, pain and fatigue than white patients. Lack of access to ... Full text Link to item Cite

Association of body composition with odds of breast cancer by molecular subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study.

Journal Article BMC Cancer · September 25, 2021 BACKGROUND: The association between obesity and breast cancer (BC) has been extensively studied among US, European and Asian study populations, with often conflicting evidence. However, despite the increasing prevalence of obesity and associated conditions ... Full text Link to item Cite

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study.

Journal Article Oncotarget · June 22, 2021 Breast cancer (BC) in Nigeria is characterized by disproportionately aggressive molecular subtypes. C-reactive protein (CRP) is associated with risk and aggressiveness for several types of cancer. We examined the association of high-sensitivity CRP (hsCRP) ... Full text Link to item Cite

Patterns of de-novo metastasis and breast cancer-specific mortality by race and molecular subtype in the SEER population-based dataset.

Journal Article Breast Cancer Res Treat · April 2021 PURPOSE: To examine patterns of de-novo metastases (mets) and association with breast cancer-specific mortality across subtypes and racial groups. METHODS: Non-Hispanic (NH) Black and NH-White patients ages 40¬†years and older with primary breast cancer (BC ... Full text Link to item Cite

RNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry.

Journal Article Lung Cancer · March 2021 OBJECTIVES: Despite disparities in lung cancer incidence and mortality, the molecular landscape of lung cancer in patients of African ancestry remains underexplored, and race-related differences in RNA splicing remain unexplored. MATERIALS AND METHODS: We ... Full text Link to item Cite

Racial and ethnic disparities in palliative care utilization among gynecological cancer patients.

Journal Article Gynecol Oncol · February 2021 BACKGROUND: Palliative care (PC) is recommended for gynecological cancer patients to improve survival and quality-of-life. Our objective was to evaluate racial/ethnic disparities in PC utilization among patients with metastatic gynecologic cancer. METHODS: ... Full text Link to item Cite

Racial disparities in palliative care utilization among metastatic gynecological cancer patients living at last follow-up: An analysis of the National Cancer Data Base.

Journal Article Data Brief · February 2021 The National Comprehensive Cancer Network recommends palliative care should be integrated in to cancer care starting from cancer diagnosis. However, traditionally palliative care is prioritized for cancer patients at the end-of-life. In our main article ti ... Full text Link to item Cite

Association of Life-Course Educational Attainment and Breast Cancer Grade in the MEND Study.

Journal Article Ann Glob Health · 2021 BACKGROUND: Nigeria reports the highest age-standardized mortality rate for breast cancer (BC) among African countries and disproportionately high rates of high-grade cancer. Histological grade is a strong predictor of mortality, and evidence suggests that ... Full text Link to item Cite

Association of Allostatic Load with All-Cause andCancer Mortality by Race and Body Mass Index in theREGARDS Cohort.

Journal Article Cancers (Basel) · June 26, 2020 Among 29,701 Black and White participants aged 45 years and older in the Reasons forGeographic and Racial Difference in Stroke (REGARDS) study, allostatic load (AL) was defined asthe sum score of established baseline risk-associated biomarkers for which pa ... Full text Link to item Cite

Alternative RNA Splicing as a Potential Major Source of Untapped Molecular Targets in Precision Oncology and Cancer Disparities.

Journal Article Clin Cancer Res · May 15, 2019 Studies of alternative RNA splicing (ARS) have the potential to provide an abundance of novel targets for development of new biomarkers and therapeutics in oncology, which will be necessary to improve outcomes for patients with cancer and mitigate cancer d ... Full text Link to item Cite

The gastrointestinal microbiota and colorectal cancer.

Journal Article Am J Physiol Gastrointest Liver Physiol · March 1, 2015 The human gut is home to a complex and diverse microbiota that contributes to the overall homeostasis of the host. Increasingly, the intestinal microbiota is recognized as an important player in human illness such as colorectal cancer (CRC), inflammatory b ... Full text Link to item Cite