Scholars@Duke
Charity Oyedeji

Charity Oyedeji

Assistant Professor of Medicine
Medicine, Hematology

Selected Publications

"Death is as Much Part of Life as Living": Attitudes and Experiences Preparing for Death from Older Adults with Sickle Cell Disease.

Journal Article Omega (Westport) · February 2025 The life-limiting and unpredictable nature of sickle cell disease (SCD) is well-established, yet there is limited literature on end-of-life planning. The purpose of this study was to describe perspectives about preparing for death for older adults with SCD ... Full text Link to item Cite

"I can't let it stop me": perspectives on aging from older adults with sickle cell disease.

Journal Article J Sick Cell Dis · 2025 OBJECTIVES: More individuals with SCD are living beyond initial life expectancy. Despite a growing population of older adults with SCD, little is known about their unique experiences and needs. Understanding the perspectives of older adults with SCD (age ≥ ... Full text Link to item Cite

Black Americans With Sickle Cell Disease (SCD) Demonstrate Accelerated Epigenetic Pace of Aging Compared to Black Americans Without SCD.

Journal Article J Gerontol A Biol Sci Med Sci · November 1, 2024 BACKGROUND: Sickle cell disease (SCD) is a chronic medical condition characterized by red blood cell sickling, vaso-occlusion, hemolytic anemia, and subsequently, end-organ damage and reduced survival. Because of this significant pathophysiology and early ... Full text Link to item Cite

Magnetic resonance imaging-guided focused ultrasound thalamotomy for essential tremor in a patient with von Willebrand disease: perioperative optimization for patients with coagulopathies. Illustrative case.

Journal Article J Neurosurg Case Lessons · June 10, 2024 BACKGROUND: Essential tremor (ET) is one of the most common movement disorders worldwide. In medically refractory ET, deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus is the current standard of care. However, DBS carries an ... Full text Link to item Cite

How I treat anemia in older adults.

Journal Article Blood · January 18, 2024 With the global growing older adult population, clinicians face the common, yet complex challenge of how to evaluate and manage anemia in this population. Older age predisposes to common causes of anemia such as nutritional deficiencies, inflammatory disor ... Full text Link to item Cite

Cognitive-motor dual-task interference in adults with sickle cell disease.

Journal Article Gait Posture · May 2023 BACKGROUND: Sickle cell disease (SCD) is a genetic disorder that causes physical and cognitive impairment due to hemolysis, painful vaso-occlusion episodes, joint avascular necrosis, and strokes. As individuals with SCD age and develop conditions impacting ... Full text Link to item Cite

Management of Older Adults with Sickle Cell Disease: Considerations for Current and Emerging Therapies.

Journal Article Drugs Aging · April 2023 People with sickle cell disease (SCD) are living longer than ever before, with the median survival increasing from age 14 years in 1973, beyond age 40 years in the 1990s, and as high as 61 years in recent cohorts from academic centers. Improvements in surv ... Full text Link to item Cite

Characterising the prevalence of overweight and obese status among adults with sickle cell disease.

Journal Article Br J Haematol · March 2023 Individuals with sickle cell disease (SCD) have historically been considered underweight. Despite increasing body mass index (BMI) in the general population, the prevalence of overweight and obese status remains unclear in the adult SCD population. Our pri ... Full text Link to item Cite

The Sickle Cell Disease Functional Assessment (SCD-FA) tool: a feasibility pilot study.

Journal Article Pilot Feasibility Stud · March 4, 2022 BACKGROUND: The life expectancy for individuals with sickle cell disease (SCD) has greatly increased over the last 50 years. Adults with SCD experience multiple complications such as cardiopulmonary disease, strokes, and avascular necrosis that lead to lim ... Full text Open Access Link to item Cite

Optimizing management of sickle cell disease in patients undergoing surgery.

Journal Article Hematology Am Soc Hematol Educ Program · December 10, 2021 Individuals with sickle cell disease (SCD) are likely to be referred for surgery at some point in their lifetime due to a high incidence of musculoskeletal and intrabdominal complications such as avascular necrosis and gallbladder disease. Preoperative opt ... Full text Link to item Cite

Adherence to Iron Chelation Therapy with Deferasirox Formulations among Patients with Sickle Cell Disease and β-thalassemia.

Journal Article J Natl Med Assoc · April 2021 BACKGROUND: Individuals with hemoglobinopathies experience complications that often require management with multiple transfusions. These chronic transfusions can lead to iron overload, which places them at increased risk of organ damage, malignancy, and ev ... Full text Link to item Cite

Geriatric assessment for older adults with sickle cell disease: protocol for a prospective cohort pilot study.

Journal Article Pilot Feasibility Stud · 2020 BACKGROUND: The life expectancy for people with sickle cell disease (SCD) has improved tremendously over the last 50 years. This population experiences hemolysis and vaso-occlusion in multiple organs that lead to complications such as cardiopulmonary disea ... Full text Link to item Cite

Assessing Feasibility of a Focused Geriatric Assessment in Older Adults with Sickle Cell Disease to Address Functional Risk Factors for Morbidity and Mortality

Journal Article Blood · November 13, 2019 BackgroundDuring the last five decades the life expectancy for people living with sickle cell disease (SCD) has improved markedly, with median survival of 61 years in recent cohorts enrolle ... Full text Open Access Cite