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Constance Margaret Johnson

Associate Professor Emerita in the School of Nursing
School of Nursing
307 Trent Drive, School of Nur, DUMC 3322, Durham, NC 27710

Selected Publications


Development of an Acute Stroke Care Seeking Framework.

Journal Article J Neurosci Nurs · December 1, 2024 BACKGROUND: A multitude of variables influence an individual's decision to seek care in emergency situations. By recognizing these variables and their impact on the timeline of an individual seeking care for a stroke, nurses have an opportunity to positive ... Full text Link to item Cite

Perceptions of HIV-Related Comorbidities and Usability of a Virtual Environment for Cardiovascular Disease Prevention Education in Sexual Minority Men With HIV: Formative Phases of a Pilot Randomized Controlled Trial.

Journal Article Journal of medical Internet research · August 2024 BackgroundSexual minority men with HIV are at an increased risk of cardiovascular disease (CVD) and have been underrepresented in behavioral research and clinical trials.ObjectiveThis study aims to explore perceptions of HIV-related comor ... Full text Cite

Enhancing foot care education and support strategies in adults with type 2 diabetes.

Journal Article Journal of the American Association of Nurse Practitioners · June 2024 BackgroundPeople with diabetes are susceptible to serious and disabling foot complications, which increase their morbidity and mortality rates. Examining the perspectives of people with diabetes on their foot care routines could help elucidate the ... Full text Cite

Patient competence in chronic illness: A concept derivation.

Journal Article Journal of clinical nursing · April 2024 Aims and objectivesThis paper aims to inform nursing and other healthcare disciplines by clearly defining patient competence and the skills required to improve self-care behaviours.BackgroundCompetence has been defined in education and le ... Full text Cite

Use of a virtual environment to promote self-management and lifestyle changes in persons with bipolar disorder.

Journal Article Archives of psychiatric nursing · April 2024 PurposeSelf-management and lifestyle interventions are a key factor in treatment outcomes for persons with bipolar disorder (BD). A virtual environment (VE), due to it's ability to provide flexibility of involvement in its platform, may be an alte ... Full text Cite

The Symptom Experience of Patients with Advanced Melanoma Undergoing Immune Checkpoint Inhibitor (ICI) Therapy.

Journal Article Seminars in oncology nursing · February 2024 ObjectivesThe advent of immune checkpoint inhibitor (ICI) therapy has vastly improved outcomes for patients with advanced melanoma. However, the symptom burden and intensity with their impact on quality-of-life (HRQoL) and functionality are hetero ... Full text Cite

Feasibility and user-experience of a virtual environment for social connection and education after stroke: A pilot study.

Journal Article Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · February 2024 ObjectivesTo evaluate the feasibility and usability of stroke survivor participation in an 8-week virtual environment intervention that provides opportunities for social support exchanges, social network interactions, and recovery education.Ma ... Full text Cite

Baby Boomer Gay Men’s Experiences with Primary Healthcare

Journal Article Journal of Homosexuality · January 1, 2024 This research explored baby boomer gay men’s experiences with primary healthcare and their perspectives of future long-term care. Baby boomer gay men’s perspectives about primary healthcare remain understudied in the United States. A descriptive qualitativ ... Full text Cite

A randomized controlled study of auricular point acupressure to manage chemotherapy-induced neuropathy: Study protocol.

Journal Article PloS one · January 2024 ObjectiveChemotherapy-induced neuropathy (CIN) significantly impacts cancer patients, leading to functional disability, diminished quality of life, and increased healthcare costs amid the ongoing opioid crisis. Auricular point acupressure (APA), a ... Full text Cite

Effectiveness of online cognitive behavioural therapy on quality of life in adults with depression: A systematic review.

Journal Article Journal of psychiatric and mental health nursing · October 2023 What is known on the subjectDepression is a leading cause of disability worldwide that negatively impacts quality of life. Talk therapy such as cognitive behavioural therapy is an effective treatment for depression. The Internet is an important to ... Full text Cite

Listening to Remotely Monitored Home-based Preferred Music for Pain in Older Black Adults with Low Back Pain: A Pilot Study of Feasibility and Acceptability.

Journal Article Pain management nursing : official journal of the American Society of Pain Management Nurses · October 2023 BackgroundLow back pain (LBP) is a complex condition that is widespread among older Black adults. Nonpharmacologic interventions are recommended as first-line therapy, but their use in practice is limited, possibly due to misunderstanding of their ... Full text Cite

Learning in a Virtual Environment to Improve Type 2 Diabetes Outcomes: Randomized Controlled Trial.

Journal Article JMIR formative research · April 2023 BackgroundGiven the importance of self-management in type 2 diabetes mellitus (T2DM), a major aspect of health is providing diabetes self-management education and support. Known barriers include access, availability, and the lack of follow through ... Full text Cite

A Nurse-Led Telehealth Program for Diabetes Foot Care: Feasibility and Usability Study

Journal Article JMIR Nursing · January 1, 2023 Background: Diabetes mellitus can lead to severe and debilitating foot complications, such as infections, ulcerations, and amputations. Despite substantial progress in diabetes care, foot disease remains a major challenge in managing this chronic condition ... Full text Cite

Patient voice in metastatic cancer: A conceptual analysis.

Journal Article Nursing forum · November 2022 AimTo analyze the concept of patient voice and discuss implications for clinical care of individuals with metastatic cancer.BackgroundThe diagnosis of metastatic cancer requires increased patient support and healthcare resource utilizatio ... Full text Cite

Cardiovascular Disease Prevention Education Using a Virtual Environment in Sexual-Minority Men of Color With HIV: Protocol for a Sequential, Mixed Method, Waitlist Randomized Controlled Trial

Journal Article JMIR Research Protocols · May 1, 2022 Background: It is estimated that 70% of all deaths each year in the United States are due to chronic conditions. Cardiovascular disease (CVD), a chronic condition, is the leading cause of death in ethnic and racial minority males. It has been identified as ... Full text Cite

Unpacking Peer Conversations in a Virtual Communitiy for Diabetes Self-Management Education and Support: Behavior Science and Linguistics Perspective.

Journal Article Studies in health technology and informatics · December 2021 Diabetes is a chronic disease that can be effectively managed and controlled using strategies such as self-management education and ongoing support. Virtual environments offer innovative and realistic settings where patients can achieve self-management edu ... Full text Cite

The Effect of Music Listening on Pain in Adults Undergoing Colonoscopy: A Systematic Review and Meta-Analysis

Journal Article Journal of Perianesthesia Nursing · October 1, 2021 Purpose: To investigate the role of music listening in reducing pain in adults undergoing colonoscopy. Design: This is a systematic review and meta-analysis of randomized control trials (RCTs) that evaluated the effect of music in reducing pain in adults u ... Full text Cite

Coping and healthcare utilization in LGBTQ older adults: A systematic review.

Journal Article Geriatric nursing (New York, N.Y.) · July 2021 PurposeThis systematic review was conducted to identify, synthesize, and elucidate the coping mechanisms described by aging lesbian, gay, bisexual, transgender, and queer (LGBTQ) adults (60+) when utilizing healthcare.MethodsA comprehensi ... Full text Cite

Recruitment and enrollment of participants in an online diabetes self-management intervention in a virtual environment.

Journal Article Contemporary clinical trials · June 2021 Effective recruitment of research participants is essential for successful randomized controlled trials and remains one of the most challenging and labor-intensive aspects of conducting research. The purpose of this manuscript is to describe recruitment me ... Full text Cite

Internet access and usage among stroke survivors and their informal caregivers: Cross-sectional study

Journal Article JMIR Formative Research · March 1, 2021 Background: Web-based interventions have shown promise for chronic disease management but have not been widely applied to populations with stroke. Existing barriers may inhibit the adoption of web-based interventions among stroke survivors and necessitate ... Full text Cite

Exchanges in a Virtual Environment for Diabetes Self-Management Education and Support: Social Network Analysis.

Journal Article JMIR diabetes · January 2021 BackgroundDiabetes remains a major health problem in the United States, affecting an estimated 10.5% of the population. Diabetes self-management interventions improve diabetes knowledge, self-management behaviors, and clinical outcomes. Widespread ... Full text Cite

User-centered design principles in the development of clinical research tools.

Journal Article Clinical trials (London, England) · December 2020 BackgroundIncreasing and sustaining the engagement of participants in clinical research studies is a goal for clinical investigators, especially for studies that require long-term or frequent involvement of participants. Technology can be used to ... Full text Cite

Integrative Review of Recruitment of Research Participants Through Facebook.

Journal Article Nursing research · November 2019 BackgroundFacebook (FB) has been widely used recently to recruit participants for adult health research. However, little is known about its effectiveness, cost, and the characteristics of participants recruited via FB when compared to other recrui ... Full text Cite

Predicting Colorectal Cancer Screening among Adults Who Have Never Been Screened: Testing the Interaction between Message Framing and Tailored Risk Feedback.

Journal Article Journal of health communication · January 2019 Providing adults tailored risk estimates of getting colorectal cancer (CRC) can increase screening. A concern is that receipt of lower risk estimates will demotivate screening; this effect may be curbed by matching level of risk with message framing. Theor ... Full text Cite

Developing Methods That Facilitate Coding and Analysis of Synchronous Conversations via Virtual Environments.

Journal Article International journal of qualitative methods · January 2019 Programs via the Internet are uniquely positioned to capture qualitative data. One reason is because the Internet facilitates the creation of a community of similar individuals who can exchange information and support related to living with a chronic illne ... Full text Cite

Reactions to online colorectal cancer risk estimates among a nationally representative sample of adults who have never been screened.

Conference Journal of behavioral medicine · June 2018 Data on the public's reactions to online tailored colorectal cancer (CRC) risk estimates are sparse. We assessed among 560 men and women aged 50-75 with no CRC screening history reactions to online tailored CRC estimated comparative risk (i.e., self vs. ot ... Full text Cite

Participation of Racial and Ethnic Minorities in Technology-Based Interventions to Self-Manage Type 2 Diabetes: A Scoping Review.

Journal Article Journal of transcultural nursing : official journal of the Transcultural Nursing Society · May 2018 PurposeStrategies to decrease societal and cultural barriers for ethnic minorities to participate in health research are well established. However, limited data are available regarding participation of ethnic minorities in mobile and Internet tech ... Full text Cite

Type 2 Diabetes Education and Support in a Virtual Environment: A Secondary Analysis of Synchronously Exchanged Social Interaction and Support.

Journal Article Journal of medical Internet research · February 2018 BackgroundVirtual environments (VEs) facilitate interaction and support among individuals with chronic illness, yet the characteristics of these VE interactions remain unknown.ObjectiveThe objective of this study was to describe social in ... Full text Cite

Diabetes Self-management Training in a Virtual Environment.

Journal Article The Diabetes educator · August 2017 Diabetes self-management training (DSMT) improves diabetes health outcomes. However, low numbers of patients receive DSMT. Using virtual environments (VEs) for DSMT is an innovative approach to removing barriers for patients. The purpose of this paper is t ... Full text Cite

Creating a sustainable collaborative consumer health application for chronic disease self-management.

Journal Article Journal of biomedical informatics · July 2017 As the prevalence of chronic diseases increase, there is a need for consumer-centric health informatics applications that assist individuals with disease self-management skills. However, due to the cost of development of these applications, there is also a ... Full text Cite

Analyzing Unstructured Communication in a Computer-Mediated Environment for Adults With Type 2 Diabetes: A Research Protocol.

Journal Article JMIR research protocols · April 2017 BackgroundIndividuals with type 2 diabetes have an increased risk for comorbidities such as heart disease, lower limb amputations, stroke, and renal failure. Multiple factors influence development of complications in a person living with type 2 di ... Full text Cite

Visualization of Multidimensional Data in Nursing Science.

Journal Article Western journal of nursing research · January 2017 Nursing scientists have long been interested in complex, context-dependent questions addressing individual- and population-level challenges in health and illness. These critical questions require multilevel data (e.g., genetic, physiologic, biologic, behav ... Full text Cite

Increasing EHR system usability through standards: Conformance criteria in the HL7 EHR-system functional model.

Journal Article Journal of biomedical informatics · October 2016 Though substantial work has been done on the usability of health information technology, improvements in electronic health record system (EHR) usability have been slow, creating frustration, distrust of EHRs and the use of potentially unsafe work-arounds. ... Full text Cite

Social Support for Diabetes Self-Management via eHealth Interventions.

Journal Article Current diabetes reports · July 2016 eHealth interventions have been increasingly used to provide social support for self-management of type 2 diabetes. In this review, we discuss social support interventions, types of support provided, sources or providers of support, outcomes of the support ... Full text Cite

Evaluation of Nursing Documentation Completion of Stroke Patients in the Emergency Department: A Pre-Post Analysis Using Flowsheet Templates and Clinical Decision Support.

Journal Article Comput Inform Nurs · February 2016 The primary aim of this performance improvement project was to determine whether the electronic health record implementation of stroke-specific nursing documentation flowsheet templates and clinical decision support alerts improved the nursing documentatio ... Full text Link to item Cite

Internet delivered diabetes self-management education: A review

Journal Article Diabetes Technology and Therapeutics · February 1, 2016 Full text Cite

Creating a Culture of Safety Around Bar-Code Medication Administration: An Evidence-Based Evaluation Framework.

Journal Article The Journal of nursing administration · January 2016 Bar-code medication administration (BCMA) effectiveness is contingent upon compliance with best-practice protocols. We developed a 4-phased BCMA evaluation program to evaluate the degree of integration of current evidence into BCMA policies, procedures, an ... Full text Cite

Facilitating palliative care referrals in the intensive care unit: a pilot project.

Journal Article Dimensions of critical care nursing : DCCN · November 2015 BackgroundPalliative care in intensive care units (ICUs) reduces costs and improves outcomes yet is consistently underused; studies suggest that screening tools increase the use of palliative services.AimsThis project piloted the use of t ... Full text Cite

Diabetes Learning in Virtual Environments: Testing the Efficacy of Self-Management Training and Support in Virtual Environments (Randomized Controlled Trial Protocol).

Journal Article Nursing research · November 2015 BackgroundOngoing self-management improves outcomes for those with Type 2 diabetes (T2D); however, there are many barriers to patients receiving assistance in this from the healthcare system and peers. Findings from our pilot study showed that a v ... Full text Cite

Foreword

Book · September 1, 2015 Full text Cite

Developing a user-friendly interface for a self-service healthcare research portal: cost-effective usability testing

Journal Article Health Systems · July 1, 2015 Usability is a critical but often overlooked factor in the design and development of healthcare information technology systems. One system increasingly being leveraged as a research and quality improvement tool is an online research portal that allows self ... Full text Cite

Utilization of electronic modified early warning score to engage rapid response team early in clinical deterioration.

Journal Article Journal for nurses in professional development · May 2015 After implementation of electronic modified early warning score to engage the rapid response team as a clinical decision support tool, we assessed the knowledge level about and usage of the tool by core staff. We identified a knowledge deficit, planned and ... Full text Cite

Internet delivered diabetes self-management education: a review.

Journal Article Diabetes technology & therapeutics · January 2015 BackgroundDiabetes self-management education is a cornerstone of successful diabetes management. Various methods have been used to reach the increasing numbers of patients with diabetes, including Internet-based education. The purpose of this arti ... Full text Cite

Factors Affecting Accuracy of Data Abstracted from Medical Records.

Journal Article PLoS One · 2015 OBJECTIVE: Medical record abstraction (MRA) is often cited as a significant source of error in research data, yet MRA methodology has rarely been the subject of investigation. Lack of a common framework has hindered application of the extant literature in ... Full text Link to item Cite

A theoretical framework for a virtual diabetes self-management community intervention.

Journal Article Western journal of nursing research · October 2014 Due to its high prevalence, chronic nature, potential complications, and self-management challenges for patients, diabetes presents significant health education and support issues. We developed and pilot-tested a virtual community for adults with type 2 di ... Full text Cite

Feasibility and preliminary effects of a virtual environment for adults with type 2 diabetes: pilot study.

Journal Article JMIR research protocols · April 2014 BackgroundInnovative interventions that empower patients in diabetes self-management (DSM) are needed to provide accessible, sustainable, cost-effective patient education and support that surpass current noninteractive interventions. Skills acquir ... Full text Cite

mHealth interventions for weight loss: a guide for achieving treatment fidelity.

Journal Article J Am Med Inform Assoc · 2014 UNLABELLED: mHealth interventions have shown promise for helping people sustain healthy behaviors such as weight loss. However, few have assessed treatment fidelity, that is, the accurate delivery, receipt, and enactment of the intervention. Treatment fide ... Full text Open Access Link to item Cite

Calling for collaboration: piloting smartphones to discover differences between users and devices.

Journal Article Teach Learn Med · 2014 BACKGROUND: Healthcare technologies and patient care have evolved rapidly. Healthcare communication techniques and technologies have lagged. PURPOSES: This pilot study was conducted at Duke University Hospital to investigate the benefits of using smartphon ... Full text Link to item Cite

Mobile health messages help sustain recent weight loss.

Journal Article Am J Med · November 2013 BACKGROUND: Using regulatory focus theory, an intervention of daily weight loss-sustaining messages was developed and tested for acceptability, feasibility, and efficacy on helping people sustain weight loss. METHODS: Participants (n = 120) were randomized ... Full text Link to item Cite

Evaluation of the use of bar-code medication administration in nursing practice using an evidence-based checklist.

Journal Article The Journal of nursing administration · November 2013 The goal of this project was to determine whether the use of bar-code medication administration complied with current evidence as to how it should be used. Using an evidence-based checklist, we performed a gap analysis on bar-code medication administration ... Full text Cite

Virtual worlds in nursing education: a synthesis of the literature.

Journal Article The Journal of nursing education · July 2013 Although the literature has highlighted the use of virtual worlds in teaching-learning, little is known about the concepts associated with this technology in nursing education. Moreover, the application of virtual worlds to education has been underdevelope ... Full text Cite

Meta-analyses of colorectal cancer risk factors.

Journal Article Cancer causes & control : CCC · June 2013 PurposeDemographic, behavioral, and environmental factors have been associated with increased risk of colorectal cancer (CRC). We reviewed the published evidence and explored associations between risk factors and CRC incidence.MethodsWe i ... Full text Cite

Development of a Theoretically Driven mHealth Text Messaging Application for Sustaining Recent Weight Loss.

Journal Article JMIR Mhealth Uhealth · May 7, 2013 BACKGROUND: Mobile phone short message service (SMS) text messaging, has the potential to serve as an intervention medium to promote sustainability of weight loss that can be easily and affordably used by clinicians and consumers. OBJECTIVE: To develop the ... Full text Open Access Link to item Cite

Exploring interpersonal behavior and team sensemaking during health information technology implementation.

Journal Article Advances in health care management · January 2013 PurposeWe examine how interpersonal behavior and social interaction influence team sensemaking and subsequent team actions during a hospital-based health information technology (HIT) implementation project.Design/methodology/approachOver ... Full text Cite

A usability problem: conveying health risks to consumers on the Internet.

Journal Article AMIA ... Annual Symposium proceedings. AMIA Symposium · January 2012 Effectively designing risk information for the public is challenging and selecting the appropriate medium to deliver disease risk information is crucial. In a usability evaluation of a colon cancer risk website, we evaluated the public's understanding and ... Cite

Health Information Seeking and Social Media Use on the Internet among People with Diabetes.

Journal Article Online journal of public health informatics · June 2011 Patients who are active and involved in their self-management and care are more likely to manage chronic conditions effectively (6, 26). With a 5-fold increase in the incidence of chronic illness over the past 20 years, access to information can provide pa ... Link to item Cite

Implementation of a user-centered framework in the development of a web-based health information database and call center.

Journal Article Journal of biomedical informatics · March 2011 As healthcare consumers increasingly turn to the World Wide Web (WWW) to obtain health information, it is imperative that health-related websites are user-centered. Websites are often developed without consideration of intended users' characteristics, lite ... Full text Cite

Assessing the feasibility of using virtual environments in distance education.

Journal Article Knowledge Management & E-Learning: An International Journal · March 2011 Abstract: Learning is an active, social process. However, many distance education programs are flat and asynchronous with limited interaction. Virtual environments may be best equipped to foster an active social learning environment that provides optimal d ... Link to item Cite

Safety issues related to the electronic medical record (EMR): synthesis of the literature from the last decade, 2000-2009.

Journal Article Journal of healthcare management / American College of Healthcare Executives · January 2011 Healthcare is a complex industry burdened by numerous and complicated clinical and administrative transactions that require many behavioral changes by patients, clinicians, and provider organizations. While healthcare information technology (HIT) is intend ... Cite

Can prospective usability evaluation predict data errors?

Journal Article AMIA Annu Symp Proc · November 13, 2010 Increasing amounts of clinical research data are collected by manual data entry into electronic source systems and directly from research subjects. For this manual entered source data, common methods of data cleaning such as post-entry identification and r ... Link to item Cite

Extensive disease small cell lung cancer dose-response relationships: implications for resistance mechanisms.

Journal Article Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · November 2010 BackgroundSome studies (but not others) suggested that high doses are beneficial in small cell lung cancer (SCLC). We hypothesized that dose-response curve (DRC) shape reflects resistance mechanisms.MethodsWe reviewed published SCLC clini ... Full text Cite

Using virtual environments to enhance nursing distance education.

Journal Article Creative nursing · August 2010 Distance education has traditionally been two-dimensional, with limited interaction. Virtual environments enhance distance education learning through real-time interaction and social collaboration that mimic the real world. Virtual environments offer the o ... Full text Cite

Risk assessment models to estimate cancer probabilities.

Journal Article Current oncology reports · November 2007 Cancer risk has become a significant research topic due to an increase in statistical risk models built to predict cancer incidence or mortality. Over the past 3 years, 15 models on the development of different types of cancer, including breast, colorectal ... Full text Cite

Building a predictive breast cancer risk model.

Journal Article AMIA ... Annual Symposium proceedings. AMIA Symposium · October 2007 The poster outlines the development of a breast cancer risk assessment tool for the World-Wide-Web based on well-established epidemiological, clinical, and genetic risk factors. ... Cite

Reasons for after-hours calls by hospital floor nurses to on-call physicians.

Journal Article Joint Commission journal on quality and patient safety / Joint Commission Resources · June 2007 Featured Publication BACKGROUND: Communication failure is a common root cause of preventable medical errors affecting hospitalized patients. A study was conducted to determine the reasons for calls made by nurses working on the general medical wards to on-call physicians from ... Cite

A new approach to building web-based interfaces for healthcare consumers.

Journal Article Electronic Journal of Health Informatics · 2007 Healthcare websites, that are influential in healthcare decision-making, must be evaluated for accuracy, readability and understandability by the average population. Most existing frameworks for designing and evaluating interactive websites focus on the ut ... Cite

The significance of cognitive modeling in building healthcare interfaces.

Journal Article International journal of medical informatics · February 2006 Featured Publication BackgroundAlthough there are many reasons that widespread adoption of healthcare information systems has not transpired, one reason is a failure to take into account the cognitive needs of the users.AimTo understand the cognitive needs of ... Full text Cite

Strategies to improve healthcare websites.

Journal Article AMIA ... Annual Symposium proceedings. AMIA Symposium · January 2006 Healthcare websites that are influential in healthcare decision-making must be evaluated for accuracy, readability and understandability by the average population. Most existing frameworks for designing and evaluating interactive websites focus on the util ... Cite

A user-centered framework for redesigning health care interfaces.

Journal Article Journal of biomedical informatics · February 2005 Featured Publication Numerous health care systems are designed without consideration of user-centered design guidelines. Consequently, systems are created ad hoc, users are dissatisfied and often systems are abandoned. This is not only a waste of human resources, but economic ... Full text Cite

An informatics tool to assess colon cancer risk.

Journal Article AMIA ... Annual Symposium proceedings. AMIA Symposium · January 2005 Featured Publication We outline the methodology used to develop an Internet-based cancer risk assessment tool and describe factors needed to create and post credible risk assessment tools or risk calculators. ... Cite

Assessing informatics students' satisfaction with a web-based courseware system.

Journal Article International journal of medical informatics · March 2004 Featured Publication This study assessed health informatics student satisfaction with two subsequent versions of Prometheus, a web-based courseware system. Prometheus versions 4 and 5 were assessed to gauge the effect of modifications to improve the usability of the system. Th ... Full text Cite

Multicolor in vitro translation.

Journal Article Nature biotechnology · September 2003 Featured Publication In vitro translation is a widely used tool for both analytical and preparative purposes. For analytical purposes, small amounts of proteins are synthesized and visualized by detection of labeled amino acids incorporated during translation. The original str ... Full text Cite

Detection of proximal colorectal cancers through analysis of faecal DNA.

Journal Article Lancet (London, England) · February 2002 Featured Publication Detection of mutations in faecal DNA represents a promising, non-invasive approach for detecting colorectal cancers in average-risk populations. One of the first practical applications of this technology involves the examination of microsatellite markers i ... Full text Cite

Detection of APC mutations in fecal DNA from patients with colorectal tumors.

Journal Article The New England journal of medicine · January 2002 Featured Publication BackgroundNoninvasive methods for detecting colorectal tumors have the potential to reduce morbidity and mortality from this disease. The mutations in the adenomatous polyposis coli (APC) gene that initiate colorectal tumors theoretically provide ... Full text Cite

Detecting colorectal cancer in stool with the use of multiple genetic targets.

Journal Article Journal of the National Cancer Institute · June 2001 Featured Publication BackgroundColorectal cancer cells are shed into the stool, providing a potential means for the early detection of the disease using noninvasive approaches. Our goal was to develop reliable, specific molecular genetic tests for the detection of col ... Full text Cite

A clean slate: Initiating a graduate program in health informatics

Journal Article M.D. Computing · 2001 Cognitive understanding of information is not a common focus in many informatics programs, but it is central to the understanding of the graduate program at the University of Texas Health Science Center. ... Cite

Increasing productivity and reducing errors through usability analysis: a case study and recommendations.

Journal Article Proceedings. AMIA Symposium · January 2000 Featured Publication The usability problems of a system often occur due to inattention to well-documented and well-established design guidelines and heuristics. These problems often lead to increased errors, user dissatisfaction, and often user abandonment. Although there are ... Cite

Antibiotic treatment of gastric lymphoma of mucosa-associated lymphoid tissue. An uncontrolled trial.

Journal Article Annals of internal medicine · July 1999 Featured Publication BackgroundGastric lymphoma of mucosa-associated lymphoid tissue (MALT) is related to Helicobacter pylori infection and may depend on this infection for growth.ObjectiveTo determine the response of gastric MALT lymphoma to antibiotic treat ... Full text Cite

Molecular approaches for colorectal cancer screening.

Journal Article European journal of gastroenterology & hepatology · March 1998 Featured Publication Molecular genetic approaches for colorectal cancer screening using stool samples have the potential to be very specific, sensitive and cost effective. K-ras oncogene mutation, observed in about 50% of the colorectal tumours, serves as an ideal target for s ... Full text Cite

Screening for colorectal cancer. A comparison of 3 fecal occult blood tests.

Journal Article Archives of internal medicine · May 1997 Featured Publication BackgroundColorectal cancer is the second leading cause of cancer deaths in the United States. Fecal occult blood testing has become a standard screening test for large-bowel cancers in the average asymptomatic population. Performance characterist ... Full text Cite

Tocolysis for recurrent preterm labor using a continuous subcutaneous infusion pump.

Journal Article The Journal of reproductive medicine · August 1994 Featured Publication This study attempted to determine the best method of treatment for patients with recurrent preterm labor: administration of terbutaline via an automated, programmable, subcutaneous infusion pump or oral terbutaline. In this retrospective, controlled study, ... Cite

Placenta praevia: Does uterine activity cause bleeding?

Journal Article Obstetrical and Gynecological Survey · January 1, 1994 Full text Cite

Characteristics of uterine activity in gestations less than 20 weeks.

Journal Article Obstetrics and gynecology · July 1990 Featured Publication Ambulatory tocodynamometry has been used for some time to record uterine activity during pregnancy. Most studies, however, have been performed in the third trimester (more than 24 weeks). The current study was initiated to assess uterine activity at earlie ... Cite

Management of preterm labor patients at home: does daily uterine activity monitoring and nursing support make a difference?

Journal Article Obstetrics and gynecology · July 1990 Featured Publication Daily home uterine activity monitoring and perinatal nursing support were compared with standard care in managing patients with recurrent preterm labor during the current pregnancy in an effort to reduce preterm birth. Sixty-seven successfully treated pret ... Cite

Management of preterm labor patients at home: Does daily uterine activity monitoring and nursing support make a difference?

Journal Article Obstetrics and Gynecology · 1990 Daily home uterine activity monitoring and perinatal nursing support were compared with standard care in managing patients with recurrent preterm labor during the current pregnancy in an effort to reduce preterm birth. Sixty-seven successfully treated pret ... Cite

Characteristics of uterine activity in gestations less than 20 weeks

Journal Article Obstetrics and Gynecology · January 1, 1990 Ambulatory tocodynamometry has been used for some time to record uterine activity during pregnancy. Most studies, however, have been performed in the third trimester (more than 24 weeks). The current study was initiated to assess uterine activity at earlie ... Cite

Management of preterm labor patients at home: Does daily uterine activity monitoring and nursing support make a difference?

Journal Article Obstetrics and Gynecology · January 1, 1990 Daily home uterine activity monitoring and perinatal nursing support were compared with standard care in managing patients with recurrent preterm labor during the current pregnancy in an effort to reduce preterm birth. Sixty-seven successfully treated pret ... Cite