Scholars@Duke
Leslie Gail Dodd

Leslie Gail Dodd

Adjunct Associate Professor in the Department of Pathology
Pathology
dodd0003@mc.duke.edu
Duke Box 3712, Durham, NC 27710
353M Davison Bldg, Durham, NC 27710

Selected Publications

Cytopathology of mesenchymal chondrosarcomas: a report and comparison of four patients.

Journal Article Cancer · August 25, 2003 BACKGROUND: Mesenchymal chondrosarcoma (MC) is an infrequent neoplasm, representing approximately 1% of all chondrosarcomas. Cytologic descriptions of MCs have been confined to rare case reports. In the current report, the authors describe their experience ... Full text Link to item Cite

Utility of fine-needle aspiration in the diagnosis of primary osteosarcoma.

Journal Article Diagn Cytopathol · December 2002 Featured Publication Fine-needle aspiration (FNA) is a reliable, safe, and cost-effective procedure with a well-established role in the diagnosis of various solid tissue neoplasms. The role of FNA in the diagnosis of primary bone tumors, including osteosarcoma (OGS), is contro ... Full text Link to item Cite

Fine-needle aspiration cytology of articular and periarticular lesions.

Journal Article Cancer · June 25, 2002 Featured Publication BACKGROUND: The cytologic diagnosis of joint and articular surface-based lesions traditionally has been accomplished by examination of fluids or effusions. Although exfoliative cytology remains an accurate diagnostic test, not all joint-based lesions will ... Full text Link to item Cite

Fine-needle aspiration diagnosis of medulloblastoma metastatic to the pelvis.

Journal Article Diagn Cytopathol · May 2001 A 25-yr-old male presented with a cerebellar mass, underwent a suboccipital craniotomy, and was diagnosed with medulloblastoma. Six months later he developed a large mass in the right iliac crest. Fine-needle aspiration biopsy (FNAB) confirmed the diagnosi ... Full text Link to item Cite

Diagnosis of hematopoietic processes by fine-needle aspiration in conjunction with flow cytometry: A review of 127 cases.

Journal Article Diagn Cytopathol · January 2001 Although fine-needle aspiration (FNA) is accepted as the method of choice for the initial evaluation of lymph nodes for metastatic carcinomas, its utility as the initial diagnostic procedure for hematopoietic processes is less established. We review our ex ... Full text Link to item Cite

Fine-needle aspiration cytology of pseudosarcomatous lesions of soft tissue.

Journal Article Diagn Cytopathol · January 2001 Featured Publication Pseudosarcomatous lesions are benign neoplasms of the musculoskeletal system that are likely to be misdiagnosed as malignant, based on clinical and histologic features. These include soft-tissue "tumors" considered reactive or reparative lesions such as no ... Full text Link to item Cite

Fine needle aspiration cytology of mucinous cystadenocarcinoma of the lung: report of a case with radiographic and histologic correlation.

Journal Article Acta Cytol · 2001 BACKGROUND: Mucinous cystadenocarcinoma of the lung is an uncommon tumor. Because it contains relatively few neoplastic cells relative to the amount of mucin produced, diagnosis of this entity, particularly on small specimens, is exceedingly difficult. CAS ... Full text Link to item Cite

Fine-needle aspiration diagnosis of psammomatous melanotic schwannoma.

Journal Article Diagn Cytopathol · July 2000 A 51-yr-old male presented with an 8-mo history of lower back pain. Computerized axial tomography (CT) and magnetic resonance imaging (MRI) studies showed a 3.5 X 3.0 cm sacral mass within the spinal canal in the region of the left S2 nerve root. A fine-ne ... Full text Link to item Cite

Cytomorphologic features of sebaceous carcinoma on fine needle aspiration.

Journal Article Acta Cytol · 2000 OBJECTIVE: To describe three cases of sebaceous carcinoma metastatic to regional lymph nodes diagnosed by fine needle aspiration (FNA). STUDY DESIGN: FNA was performed using standard techniques. A portion of each specimen was stained with Diff-Quick (Dade, ... Full text Link to item Cite

Detection of trisomy 12 by fluorescence in situ hybridization on archival cytopathologic material in chronic lymphocytic leukemia/small lymphocytic lymphoma.

Journal Article Acta Cytol · 2000 OBJECTIVE: To evaluate fluorescence in situ hybridization (FISH) for the detection of trisomy 12 in archival cytologic specimens of chronic lymphocytic leukemia/small lymphocytic lymphoma. STUDY DESIGN: The cytopathology database was searched for all cases ... Full text Link to item Cite

Do proficiency test results correlate with the work performance of screeners who screen Papanicolaou smears?

Journal Article Am J Clin Pathol · December 1999 Featured Publication We rescreened Papanicolaou smear slides from 40,245 women, which had been examined by 81 cytology screeners, scored the screeners' work performance, and compared these scores with the results of the screeners' performance on glass slide and computer-based ... Full text Link to item Cite

Diagnosis of anaplastic large-cell lymphoma, including multifocal osseous KI-1 lymphoma, by fine-needle aspiration biopsy.

Journal Article Diagn Cytopathol · September 1999 We present the fine-needle aspiration (FNA) findings of 4 cases of anaplastic (Ki-1) large-cell lymphoma (ALCL). A primary diagnosis of ALCL was made on FNA material in 2 cases, of which one was a multifocal osseous Ki-1 lymphoma. In the other 2 patients w ... Full text Link to item Cite

Indeterminate findings on imaging-guided biopsy: should additional intervention be pursued?

Journal Article AJR Am J Roentgenol · August 1999 OBJECTIVE: Our purpose was to determine the outcome of patients in whom the results of imaging-guided biopsies were indeterminate and to examine factors that may affect outcome. MATERIALS AND METHODS: During a 25-month period, 619 consecutive imaging-guide ... Full text Link to item Cite

Fine-needle aspiration with flow cytometric immunophenotyping for primary diagnosis of intra-abdominal lymphomas.

Journal Article Diagn Cytopathol · August 1999 Cytomorphology in conjunction with immunophenotypic characterization is becoming increasingly used for the primary diagnosis of non-Hodgkin's lymphomas (NHL). This combination is especially advantageous for the diagnosis of intra-abdominal and intrathoraci ... Full text Link to item Cite

Fine-needle aspiration findings in idiopathic retroperitoneal fibrosis.

Journal Article Diagn Cytopathol · July 1999 Idiopathic retroperitoneal fibrosis (IRF) is an inflammatory and fibrosing process that can be complicated by periureteral encasement, ureteral obstruction, and subsequent renal failure if left untreated. Unfortunately, treatment is often delayed due to th ... Full text Link to item Cite

A prospective comparison of fiberoptic transbronchial needle aspiration and bronchial biopsy for bronchoscopically visible lung carcinoma.

Journal Article Cancer · June 25, 1999 BACKGROUND: Fiberoptic bronchoscopy is the most common modality used to diagnose endobronchial carcinoma. The authors prospectively compared the sensitivity of endobronchial needle aspiration (EBNA) and immediate cytologic assessment with bronchial biopsy ... Full text Link to item Cite

Fine-needle aspiration cytology of "ancient" schwannoma.

Journal Article Diagn Cytopathol · May 1999 The term "ancient" schwannoma was proposed for a group of neural tumors showing degenerative changes and marked nuclear atypia. Prior to the realization that the observed atypia was a regressive phenomenon, many of these lesions were erroneously diagnosed ... Full text Link to item Cite

Imaging-guided percutaneous biopsy of focal splenic lesions: update on safety and effectiveness.

Journal Article AJR Am J Roentgenol · April 1999 OBJECTIVE: The purpose of this study is to determine the safety and effectiveness of percutaneous imaging-guided biopsy in the diagnosis of focal splenic lesions. MATERIALS AND METHODS: From May 1995 to November 1997, 20 imaging-guided biopsies of focal sp ... Full text Link to item Cite

Diagnosis of posttransplant granulocytic sarcoma by fine-needle aspiration cytology and flow cytometry.

Journal Article Diagn Cytopathol · February 1999 We describe a patient who developed granulocytic sarcomas of the mesentery and breast approximately 4 yrs following an allogenic bone marrow transplantation for acute myeloblastic leukemia. The diagnosis was made by a combination of fine-needle aspiration ... Full text Link to item Cite

Features of benign granular cell tumor on fine needle aspiration.

Journal Article Acta Cytol · 1999 OBJECTIVE: To describe the cytomorphologic features of benign granular cell tumor (GCT) on fine needle aspiration (FNA) biopsy and discuss the differential diagnosis. STUDY DESIGN: We reviewed three fine needle aspirates of surgically confirmed benign GCT. ... Full text Link to item Cite

Signet ring adenocarcinoma metastatic to the bronchus and mimicking goblet cell hyperplasia. A case report.

Journal Article Acta Cytol · 1999 BACKGROUND: Goblet cells in the lower respiratory tract are metaplastic bronchial epithelial cells usually associated with asthma or chronic bronchitis. Goblet cells acquire their name by a tendency to distend with mucus, with subsequent distortion in cell ... Full text Link to item Cite

Cytologic findings in vitreous fluids. Analysis of 74 specimens.

Journal Article Acta Cytol · 1999 OBJECTIVE: To review the cytologic findings of vitreous specimens and propose a simplified approach to them. STUDY DESIGN: Seventy-four vitreous specimens from 60 patients obtained either during a pars plana vitrectomy or by vitreous aspiration were review ... Full text Link to item Cite

Fine-needle aspiration of neural lesions.

Journal Article Diagn Cytopathol · January 1999 The cytomorphologic features of 13 neural lesions sampled by fine-needle aspiration (FNA) are reviewed. The frequencies at which various architectural features including Verocay bodies, filamentous background, and vascular arcades were present was recorded ... Full text Link to item Cite

Logistic regression analysis of low grade spindle cell lesions. A cytologic study.

Journal Article Acta Cytol · 1999 OBJECTIVE: To identify key diagnostic cytologic criteria for various low grade spindle cell lesions. STUDY DESIGN: We reviewed 20 synovial sarcomas, 18 benign neural tumors, 10 reparative lesions, 24 other benign and 27 additional malignant low grade spind ... Full text Link to item Cite

Middle ear carcinoid: an indolent tumor with metastatic potential.

Journal Article Head Neck · January 1999 BACKGROUND: Neuroendocrine tumors of the head and neck region may present problems in diagnosis. Middle ear carcinoid is a rare, recently recognized tumor, which to date has not been reported to metastasize. METHODS: We report the case of a 64-year-old man ... Full text Link to item Cite

Utility of fine-needle aspiration in the diagnosis of recurrent pulmonary lymphangioleiomyomatosis: a case report.

Journal Article Diagn Cytopathol · December 1998 Pulmonary lymphangioleiomyomatosis (PLAM) is a rare disease of undetermined cause that almost exclusively occurs in women of child-bearing age and is characterized by distinct clinical, radiologic, and pathologic findings. PLAM is usually fatal unless trea ... Full text Link to item Cite

"Dedifferentiated" chordoma: a case report of the cytomorphologic findings on fine-needle aspiration.

Journal Article Diagn Cytopathol · November 1998 Chordomas are relatively rare neoplasms occurring at both ends of a neuro axis. The majority follow an indolent course of multiple local recurrences, ultimately leading to the patient's death. Rare examples have been associated with sarcomatous components, ... Full text Link to item Cite

Not by blood alone: diagnosis of hemangiomas by fine-needle aspiration.

Journal Article Diagn Cytopathol · October 1998 Hemangiomas are common vascular neoplasms which are being radiographically detected and biopsied with increasing frequency during the workup of patients with malignant disease. The increasing confidence of radiologists in biopsying these lesions is in cont ... Full text Link to item Cite

Fine-needle aspiration of gastrointestinal stromal tumors.

Journal Article Am J Clin Pathol · April 1998 Gastrointestinal stromal tumors are a group of neoplasms encompassing leiomyoma, leiomyosarcoma, and an epithelioid variant of leiomyosarcoma, as well as lesions expressing neural differentiation. These neoplasms are rare and account for 1% of all gastroin ... Full text Link to item Cite

Cytologic examination of urine from patients with interstitial cystitis.

Journal Article Acta Cytol · 1998 OBJECTIVE: To perform a cytologic examination of urine from patients with interstitial cystitis (IC). STUDY DESIGN: Patients included in this study fit the definition of IC established by the National Institute of Arthritis, Diabetes, Digestive and Kidney ... Full text Link to item Cite

Fine needle aspiration of osteogenic sarcoma metastatic to the lung. A report of four cases.

Journal Article Acta Cytol · 1998 BACKGROUND: Osteogenic sarcoma (OGS) is a relatively rare, highly malignant neoplasm of bone with a tendency to metastasize to the lung. Resection of pulmonary metastases in selected instances can increase survival and likelihood of a cure. To date, fine n ... Full text Link to item Cite

Fine-needle aspiration of epithelioid malignant peripheral nerve sheath tumor (epithelioid malignant schwannoma).

Journal Article Diagn Cytopathol · September 1997 The epithelioid variant of malignant peripheral nerve sheath tumor (MPNST), also known as malignant epithelioid schwannoma, is a relatively rare and recently characterized clinicopathologic entity. The epithelioid variant of MPNST shares many clinical feat ... Full text Link to item Cite

Intramammary lymph nodes: cytologic findings and implications for fine-needle aspiration cytology diagnosis of breast nodules.

Journal Article Diagn Cytopathol · September 1997 The recognition of intramammary lymphoid proliferations is important because smears of these proliferations would be judged as insufficient by several of the published criteria for specimen adequacy. Alternatively, some might be confused with medullary car ... Full text Link to item Cite

Salivary gland lesions with a prominent lymphoid component: cytologic findings and differential diagnosis by fine-needle aspiration biopsy.

Journal Article Diagn Cytopathol · September 1997 Fine-needle aspiration (FNA) is an accepted technique for the preoperative diagnosis of salivary gland nodules. The majority of salivary gland nodules are pleomorphic adenomas and offer little difficulty in diagnosis. Most diagnostically difficult lesions ... Full text Link to item Cite

Fine-needle aspiration cytology findings in a case of aggressive angiomyxoma: a case report and review of the literature.

Journal Article Diagn Cytopathol · May 1997 Aggressive angiomyxomas are uncommon but distinct soft-tissue neoplasms occurring predominantly in the pelvis and peritoneum of females, but they have occasionally been reported in association with inguinal hernias in males. Histologically, these neoplasms ... Full text Link to item Cite

Intratumoral heterogeneity in primary breast carcinoma: study of concurrent parameters.

Journal Article J Surg Oncol · April 1997 BACKGROUND AND OBJECTIVE: Intratumoral heterogeneity for prognostic factors (ploidy, proliferation, hormone receptor positivity) has been demonstrated in primary breast carcinoma by both flow cytometric and image analysis methods. Previously, heterogeneity ... Full text Link to item Cite

Cytologic findings in tenosynovial giant cell tumors investigated by fine-needle aspiration cytology.

Journal Article Diagn Cytopathol · April 1997 Tenosynovial giant cell tumor is a relatively common benign proliferation affecting the articular and periarticular soft tissues. Cytologic findings on smears obtained by fine-needle aspiration are rather characteristic and include a mixture of oval or pol ... Full text Link to item Cite

Fine-needle aspiration of the liver and pancreas: a cytology primer for radiologists.

Journal Article Radiology · April 1997 Fine-needle aspiration (FNA) is increasing in popularity as a means of diagnosing mass lesions in intraabdominal organs. With use of radiologic guidance for needle placement, this technique is an effective way to obtain diagnostic material. In selected ins ... Full text Link to item Cite

Endoscopic brush cytology of the upper urinary tract. Evaluation of its efficacy and potential limitations in diagnosis.

Journal Article Acta Cytol · 1997 OBJECTIVE: To evaluate the efficacy of endoscopic brush cytology in diagnosing transitional cell carcinoma of the upper urinary tract. STUDY DESIGN: Sixty-three endoscopic brush cytology specimens from 48 patients were compared with corresponding cytologic ... Full text Link to item Cite

Fine-needle aspiration of inflammatory carcinoma of the breast.

Journal Article Diagn Cytopathol · December 1996 Inflammatory carcinoma of the breast is an uncommon clinicopathologic entity which is characterized by a distinctive clinical appearance and poor prognosis. Histopathologically, it is characterized by plugging of dermal lymphatics with tumor emboli. Becaus ... Full text Link to item Cite

Fine-needle aspiration cytology of ganglion cysts.

Journal Article Diagn Cytopathol · December 1996 Ganglion cyst is a relatively common lesion resulting from mucoid, cystic degeneration of soft tissues adjacent to a joint space. Aspiration of cyst contents has been increasingly advocated as a diagnostic and, in some instances, therapeutic modality. We r ... Full text Link to item Cite

Squamous cells in fine-needle aspiration biopsies of salivary gland lesions: potential pitfalls in cytologic diagnosis.

Journal Article Diagn Cytopathol · December 1996 A spectrum of neoplastic and non-neoplastic lesions of the salivary glands may contain squamous cells. These include chronic sialadenitis, lymphoepithelial cyst, pleomorphic adenoma, Warthin's tumor, mucoepidermoid carcinoma, and squamous cell carcinoma. T ... Full text Link to item Cite

Cytologically low grade malignancies: an important interpretative pitfall responsible for false negative diagnoses in fine-needle aspiration of the breast.

Journal Article Diagn Cytopathol · September 1996 Failure to diagnose breast carcinoma by fine-needle aspiration (FNA) is a major obstacle to expanded use of that technique. While the majority of false negative diagnoses are due to inadequate sampling and insufficient specimens, a significant minority of ... Full text Link to item Cite

Prospective correlation of cervicovaginal cytologic and histologic specimens.

Journal Article Am J Clin Pathol · September 1996 An effective, prospective, computer-guided method of correlation is reported. The mechanism for identification of cases, comparison of diagnoses, and reconciliation of discrepancies are explained. The results are similar to prior, retrospective, correlatio ... Full text Link to item Cite

Fine-needle aspiration of primary gallbladder carcinoma.

Journal Article Diagn Cytopathol · August 1996 Primary carcinoma of the gallbladder is a rare neoplasm that is frequently difficult to diagnose preoperatively. The obstacles to diagnosis include vague symptoms and the relative inaccessibility of the gallbladder and cystic duct to biopsy. Cytological de ... Full text Link to item Cite

Fine-needle aspiration of a primary right atrial myxoma.

Journal Article Diagn Cytopathol · March 1996 Cardiac myxomas are rare neoplasms usually diagnosed by echocardiography. Preoperative tissue diagnosis is usually not obtained because of the location of these neoplasms. Their cytologic appearance has only been reported from touch imprints of operative s ... Full text Link to item Cite

Calcifying fibrous pseudotumor of pleura. A report of three cases of a newly described entity involving the pleura.

Journal Article Am J Clin Pathol · February 1996 A newly recognized distinctive fibrous soft tissue lesion called "calcifying fibrous pseudotumor" (CFPT) was recently described in the soft tissues of the extremities, trunk, scrotum, groin, neck, or axilla. To date, CFPT has not been described in the pleu ... Full text Link to item Cite

Renal epithelial dysplasia.

Journal Article Am J Surg Pathol · November 1995 Link to item Cite

Glomus jugulare tumor metastatic to the sacrum after high-dose radiation therapy: case report.

Journal Article Neurosurgery · November 1995 A 47-year-old woman with left ear pain and hearing loss was diagnosed with a glomus jugulare tumor for which she received radiation therapy as the primary treatment. Over a period of 20 years, she developed temporal bone necrosis, brain stem calcifications ... Full text Link to item Cite

Mucinous cystic tumor of the pancreas: an analysis of FNA characteristics with an emphasis on the spectrum of malignancy associated features.

Journal Article Diagn Cytopathol · March 1995 Featured Publication Previously, pancreatic mucinous cystic tumors were classified as either benign (cystadenoma) or malignant (cystadenocarcinoma). Descriptions of the fine-needle aspiration (FNA) findings of these neoplasms have heretofore emphasized malignant cytologic char ... Full text Link to item Cite

Fine-needle aspiration cytology of adenoid (acantholytic) squamous-cell carcinoma.

Journal Article Diagn Cytopathol · March 1995 Adenoid squamous-cell carcinoma (ASCCa) is an uncommon cancer which occurs most frequently in the skin of the head and neck region of elderly, sun-exposed individuals. Histologically, ASCCa is characterized by gland-like, "adenoid" cell groups with a centr ... Full text Link to item Cite

Congenital cystic adenomatoid malformation in adults: CT findings.

Journal Article J Comput Assist Tomogr · 1995 OBJECTIVE: Congenital cystic adenomatoid malformation (CAM) of the lung usually presents in children, although it has rarely been described in adults. The aim of this study was to review the clinical history and the CT findings in adults with pathologicall ... Full text Link to item Cite

Fine-needle aspiration of pancreatic extramedullary plasmacytoma: possible confusion with islet cell tumor.

Journal Article Diagn Cytopathol · 1994 We report two cases of extramedullary plasmacytoma (EMP) of the pancreas, diagnosed by fine-needle aspiration (FNA). Plasmacytoma of the pancreas is a rare neoplasm with only 12 cases recorded in the literature. Because of its scarcity and the cytomorpholo ... Full text Link to item Cite

Myoepithelioma of the parotid. Report of a case initially examined by fine needle aspiration biopsy.

Journal Article Acta Cytol · 1994 Fine needle aspiration (FNA) biopsy of a large, deep lobe of a parotid mass revealed a uniform population of small, spindled cells with no distinctive cytologic features. Biopsy and later resection of the mass revealed a myoepithelioma. Myoepithelioma is a ... Link to item Cite

Fine-needle aspiration cytology of silicone granulomas in the augmented breast.

Journal Article Diagn Cytopathol · October 1993 Featured Publication We studied 12 aspirates from 10 patients who underwent diagnostic fine-needle aspiration cytology (FNAC) of an augmented or reconstructed breast. Six patients were augmented with silicone gel-filled implants and four patients had silicone liquid injections ... Full text Link to item Cite

Extramedullary plasmacytoma of the pancreas.

Journal Article Am J Clin Oncol · August 1993 Full text Link to item Cite

Quality-assurance study of simultaneously sampled, non-correlating cervical cytology and biopsies.

Journal Article Diagn Cytopathol · 1993 Featured Publication As part of a quality assurance study, we reviewed 223 cases of simultaneously sampled cervical smears and biopsies that showed a significant lack of correlation for squamous dysplasia or carcinoma. In 153 of the 223 cases (68.6%), the cytology was negative ... Full text Link to item Cite

A 35-year experience with the post-sophomore fellowship in pathology: analysis of its effectiveness as a recruitment resource.

Journal Article Hum Pathol · April 1992 Featured Publication Recent reports have indicated a shortage of pathologists coming out of training programs over the next few years. This is due, in part, to a decrease in the number of medical students entering pathology and an overall decline in the popularity of the field ... Full text Link to item Cite

Prevalence of non-A,non-B hepatitis/hepatitis C virus antibody in human immunoglobulins.

Journal Article Am J Clin Pathol · January 1992 Human intravenous immunoglobulins prepared by the cold ethanol fractionation technique of Cohn are considered safe with respect to infectivity. However, there have been several instances of transmission of both hepatitis B and non-A,non-B hepatitis viruses ... Full text Link to item Cite

Midline nasal destruction in cocaine abusers.

Journal Article Otolaryngol Head Neck Surg · November 1991 Idiopathic midline destructive disease (IMDD) is a diagnosis of exclusion in patients who manifest midline nasal necrosis with no specific etiology such as infection, tumor, or Wegener's granulomatosis. Recently, a group of cocaine abusers has been identif ... Full text Link to item Cite

Osteogenic sarcoma of the head and neck. The UCLA experience.

Journal Article Arch Otolaryngol Head Neck Surg · July 1991 Eighteen cases of osteogenic sarcoma of the head and neck were treated at our institution between 1955 and 1987. The patients' ages ranged from 5 to 73 years, with a median age of 28 years. The sex distribution was equal. Follow-up ranged from 1 to 276 mon ... Full text Link to item Cite

Prevalence of non-A, non-B hepatitis/hepatitis C virus antibody in laboratory quality-assurance sera.

Journal Article Clin Chem · June 1991 Quality-assurance sera (QAS) are prepared from pooled sera composed of thousands of individual donations. Previous studies documented that a substantial percentage of individual QAS test positive for viral disease markers, including antibodies to human imm ... Link to item Cite

Disseminated coccidioidomycosis detected by percutaneous liver biopsy in a liver transplant recipient.

Journal Article Am J Clin Pathol · January 1990 The authors report the first case, to their knowledge, of disseminated coccidioidomycosis occurring in a liver transplant recipient. The case is also interesting in that the diagnosis of disseminated coccidioidomycosis was made fortuitously, only after fin ... Full text Link to item Cite