Erin Macdonald

Journal Article Metabolites · October 2024 Background/Objectives: Despite the role of metabolism in breast cancer metastasis, we still cannot predict which breast tumors will progress to distal metastatic lesions or remain dormant. This work uses metabolic imaging to study breast cancer cell ... Full text Cite

Optimization of non-endorectal prostate MR image quality using PI-QUAL: A multidisciplinary team approach.

Journal Article Eur J Radiol · September 2023 PURPOSE: To evaluate the utility of the PI-QUAL score in assessing protocol changes aimed to improve image quality from a non-endorectal coil prostate MR imaging protocol during a 9-month quality improvement (QI) project and to quantify the inter-reader ag ... Full text Link to item Cite

Variations in signal-to-noise characteristics of tissue-equivalent attenuators for mammographic automatic exposure control system performance evaluation.

Journal Article Journal of applied clinical medical physics · February 2023 PurposeThis work investigates the impact of tissue-equivalent attenuator choice on measured signal-to-noise ratio (SNR) for automatic exposure control (AEC) performance evaluation in digital mammography. It also investigates how the SNR changes fo ... Full text Cite

Proton density water fraction as a reproducible MR-based measurement of breast density.

Journal Article Magnetic resonance in medicine · April 2022 PurposeTo introduce proton density water fraction (PDWF) as a confounder-corrected (CC) MR-based biomarker of mammographic breast density, a known risk factor for breast cancer.MethodsChemical shift encoded (CSE) MR images were acquired u ... Full text Cite

Hyperpolarized ¹³C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential.

Journal Article Metabolites · April 2021 This study uses dynamic hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) ... Full text Cite

Improved reconstruction stability for chemical shift encoded hyperpolarized ¹³ C magnetic resonance spectroscopic imaging using k-t spiral acquisitions.

Journal Article Magnetic resonance in medicine · July 2020 PurposeA multiecho, field of view (FOV)-oversampled k-t spiral acquisition and direct iterative decomposition of water and fat with echo asymmetry and least-squares estimation reconstruction is demonstrated to improve the stability of hyperpolariz ... Full text Cite

Measuring the link between cardiac mechanical function and metabolism during hyperpolarized ¹³C-pyruvate magnetic resonance experiments.

Journal Article Magnetic resonance imaging · May 2020 PurposeThe goal of this study was to develop a methodology to investigate the relationship between contractile function and hyperpolarized (HP) [1-13C]pyruvate metabolism in a small animal model. To achieve sufficient signal from HP Full text Cite

A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures.

Journal Article Magnetic resonance in medicine · May 2019 PurposeFluorescence lifetime imaging microscopy (FLIM) of endogenous fluorescent metabolites permits the measurement of cellular metabolism in cell, tissue and animal models. In parallel, magnetic resonance spectroscopy (MRS) of dynamic nuclear (h ... Full text Cite

Normal values for transbulbar sonography and magnetic resonance imaging of the optic nerve sheath diameter (ONSD) in children and adolescents.

Journal Article Ultraschall in der Medizin (Stuttgart, Germany : 1980) · February 2015 PurposeTo establish normal values of the optic nerve sheath diameter (ONSD) in children and adolescents for transbulbar sonography and magnetic resonance imaging.Materials and methodsIn 99 children and adolescents (age: 5.6 - 18.6 years, ... Full text Cite

Measurement of the optic nerve sheath diameter in children: Comparison between transbulbar sonography and magnetic resonance imaging

Journal Article Ultraschall in der Medizin · January 1, 2012 Purpose: To evaluate the accuracy of measurements of the optic nerve sheath diameter (ONSD) in children by comparing transbulbar sonography with magnetic resonance imaging (MRI). Materials and Methods: 65 children (age: 3mo-17 y; mean age: 11.3 y) underwen ... Full text Cite

[Sonographic detection of normal appendix in children and adolescents].

Journal Article Ultraschall in der Medizin (Stuttgart, Germany : 1980) · June 2008 PurposeThe frequency of depiction of the normal appendix by real time B-mode sonography in children was evaluated in a prospective study.Materials and methodsIn 274 consecutive patients, age one to nineteen, without abdominal pain, depict ... Full text Cite