Igor Akushevich

Journal Article The journals of gerontology. Series A, Biological sciences and medical sciences · October 2018 The special design of the Long Life Family Study provides a unique opportunity to investigate the genetics of human longevity by analyzing data on exceptional lifespans in families. In this article, we performed two series of genome wide association studie ... Full text Cite

Time trends in the prevalence of cancer and non-cancer diseases among older U.S. adults: Medicare-based analysis.

Journal Article Exp Gerontol · September 2018 Longer lifespan is accompanied by a larger number of chronic diseases among older adults. Because of a growing proportion of older adults in the U.S., this brings the problem of age-related morbidity to the forefront as a major contributor to rising medica ... Full text Link to item Cite

Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.

Journal Article Experimental gerontology · July 2018 Despite evident success in clarifying many important features of Alzheimer's disease (AD) the efficient methods of its prevention and treatment are not yet available. The reasons are likely to be the fact that AD is a multifactorial and heterogeneous healt ... Full text Cite

Radiative effects in deep virtual Compton scattering

Journal Article Physical Review D · July 1, 2018 Radiative corrections to the cross sections of photon electroproduction and the single spin asymmetries induced by the interference between the Bethe-Heitler and deep virtual Compton scattering amplitudes are calculated within the leading log approximation ... Full text Cite

Identifying the causes of the changes in the prevalence patterns of diabetes in older U.S. adults: A new trend partitioning approach.

Journal Article J Diabetes Complications · April 2018 AIMS: To identify how efforts to control the diabetes epidemic and the resulting changes in diabetes mellitus, type II (T2D) incidence and survival have affected the time-trend of T2D prevalence. METHODS: A newly developed method of trend decomposition was ... Full text Link to item Cite

Time Trends in the Prevalence of Neurocognitive Disorders and Cognitive Impairment in the United States: The Effects of Disease Severity and Improved Ascertainment.

Journal Article J Alzheimers Dis · 2018 BACKGROUND: Trends in the prevalence of cognitive impairment (CI) based on cognitive assessment instruments are often inconsistent with those of neurocognitive disorders (ND) based on Medicare claims records. OBJECTIVE: We hypothesized that improved ascert ... Full text Link to item Cite

Mortality and Health Outcomes in North Carolina Communities Located in Close Proximity to Hog Concentrated Animal Feeding Operations.

Journal Article N C Med J · 2018 BACKGROUND Life expectancy in southeastern North Carolina communities located in an area with multiple concentrated animal feeding operations (CAFOs) after adjusting for socioeconomic factors remains low. We hypothesized that poor health outcomes in this r ... Full text Link to item Cite

Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery.

Journal Article Anesth Analg · October 2017 BACKGROUND: Declining platelet counts may reveal platelet activation and aggregation in a postoperative prothrombotic state. Therefore, we hypothesized that nadir platelet counts after on-pump coronary artery bypass grafting (CABG) surgery are associated w ... Full text Open Access Link to item Cite

Theory of partitioning of disease prevalence and mortality in observational data.

Journal Article Theor Popul Biol · April 2017 In this study, we present a new theory of partitioning of disease prevalence and incidence-based mortality and demonstrate how this theory practically works for analyses of Medicare data. In the theory, the prevalence of a disease and incidence-based morta ... Full text Open Access Link to item Cite

stpm: an R package for stochastic process model.

Journal Article BMC bioinformatics · February 2017 BackgroundThe Stochastic Process Model (SPM) represents a general framework for modeling the joint evolution of repeatedly measured variables and time-to-event outcomes observed in longitudinal studies, i.e., SPM relates the stochastic dynamics of ... Full text Open Access Cite

Circulatory Diseases and Aging

Chapter · October 6, 2016 Age patterns of incidence rates of major circulatory diseases (CDs), their time trends, risk factors, and other characteristics capable of contributing to the debates on the role of aging in the deterioration of human health are investigated using standard ... Full text Cite

Grading Aortic Stenosis With Mean Gradient and Aortic Valve Area: A Comparison Between Preoperative Transthoracic and Precardiopulmonary Bypass Transesophageal Echocardiography.

Journal Article J Cardiothorac Vasc Anesth · October 2016 OBJECTIVE: The authors hypothesized that average precardiopulmonary bypass (pre-CPB) transesophageal echocardiographic (TEE) mean gradient (PGm) and aortic valve area (AVA) values would be significantly different from preoperative transthoracic (TTE) value ... Full text Open Access Link to item Cite

Discordance in Grading Methods of Aortic Stenosis by Pre-Cardiopulmonary Bypass Transesophageal Echocardiography.

Journal Article Anesth Analg · April 2016 BACKGROUND: Current guidelines define severe aortic valve stenosis (AS) as an aortic valve area (AVA) ≤1.0 cm by the continuity equation and mean gradient (ΔPm) ≥ 40 mm Hg. However, these measurements can be discordant when classifying AS severity. Approxi ... Full text Open Access Link to item Cite

Resistance to stresses and reliability of biological systems: Insights for genetic studies of human aging, health, and longevity

Conference Proceedings 2nd International Symposium on Stochastic Models in Reliability Engineering Life Science and Operations Management Smrlo 2016 · March 11, 2016 Connection between stress resistance and longevity in biological organisms is widely discussed and confirmed experimentally. Much less is known about the roles of genetic and non-genetic factors in regulation of such connection. Earlier studies emphasized ... Full text Open Access Cite

A Systematic Review of Conceptual Frameworks of Medical Complexity and New Model Development.

Journal Article J Gen Intern Med · March 2016 BACKGROUND: Patient complexity is often operationalized by counting multiple chronic conditions (MCC) without considering contextual factors that can affect patient risk for adverse outcomes. OBJECTIVE: Our objective was to develop a conceptual model of co ... Full text Open Access Link to item Cite

Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants.

Journal Article Biogerontology · February 2016 Complex diseases are major contributors to human mortality in old age. Paradoxically, many genetic variants that have been associated with increased risks of such diseases are found in genomes of long-lived people, and do not seem to compromise longevity. ... Full text Open Access Cite

How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity.

Journal Article Biogerontology · February 2016 Increasing proportions of elderly individuals in developed countries combined with substantial increases in related medical expenditures make the improvement of the health of the elderly a high priority today. If the process of aging by individuals is a ma ... Full text Open Access Cite

How Genes Modulate Patterns of Aging-Related Changes on the Way to 100: Biodemographic Models and Methods in Genetic Analyses of Longitudinal Data.

Journal Article North American actuarial journal : NAAJ · January 2016 Background and objectiveTo clarify mechanisms of genetic regulation of human aging and longevity traits, a number of genome-wide association studies (GWAS) of these traits have been performed. However, the results of these analyses did not meet ex ... Full text Open Access Cite

Pure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures.

Journal Article Frontiers in genetics · January 2016 This paper shows that the effects of causal SNPs on lifespan, estimated through GWAS, may be confounded and the genetic structure of the study population may be responsible for this effect. Simulation experiments show that levels of linkage disequilibrium ... Full text Open Access Cite

Trends in Treatment Patterns and Outcomes for Ductal Carcinoma In Situ.

Journal Article J Natl Cancer Inst · December 2015 BACKGROUND: Impact of contemporary treatment of pre-invasive breast cancer (ductal carcinoma in situ [DCIS]) on long-term outcomes remains poorly defined. We aimed to evaluate national treatment trends for DCIS and to determine their impact on disease-spec ... Full text Link to item Cite

Cardiovascular comorbidities and survival of lung cancer patients: Medicare data based analysis.

Journal Article Lung Cancer · April 2015 OBJECTIVES: To evaluate the role of cardiovascular disease (CVD) comorbidity in survival of patients with non-small cell lung cancer (NSCLC). MATERIALS AND METHODS: The impact of seven CVDs (at the time of NSCLC diagnosis and during subsequent follow-up) o ... Full text Open Access Link to item Cite

Benefit of adjuvant chemotherapy after resection of stage II (T1-2N1M0) non-small cell lung cancer in elderly patients.

Journal Article Ann Surg Oncol · February 2015 BACKGROUND: We evaluated the use and efficacy of adjuvant chemotherapy after resection of T1-2N1M0 non-small cell lung cancer (NSCLC) in elderly patients. METHODS: Factors associated with the use of adjuvant chemotherapy in patients older than 65 years of ... Full text Open Access Link to item Cite

Use of mobile tablet devices and reduction in time to perioperative transesophageal echocardiography reporting: a historical cohort study.

Journal Article Can J Anaesth · January 2015 PURPOSE: Timely communication of intraoperative transesophageal echocardiography (TEE) findings to the postoperative care team is critical to optimizing patient care. We compared the use of a personal computer (PC) system with the use of a mobile tablet de ... Full text Open Access Link to item Cite

Radiative corrections beyond the ultra relativistic limit in unpolarized ep elastic and Møller scatterings for the PRad Experiment at Jefferson Laboratory

Journal Article European Physical Journal A · January 1, 2015 The clear 7σ discrepancy between measurements of the proton charge radius from muonic hydrogen Lamb shifts and those from hydrogen Lamb shift and electron scattering lead to both intense theoretical and experimental efforts to understand and explain this d ... Full text Open Access Cite

Genetics of aging, health, and survival: dynamic regulation of human longevity related traits.

Journal Article Frontiers in genetics · January 2015 BackgroundThe roles of genetic factors in human longevity would be better understood if one can use more efficient methods in genetic analyses and investigate pleiotropic effects of genetic variants on aging and health related traits.Data and ... Full text Open Access Cite

Causal effects of time-dependent treatments in older patients with non-small cell lung cancer.

Journal Article PLoS One · 2015 BACKGROUND: Treatment selection for elderly patients with lung cancer must balance the benefits of curative/life-prolonging therapy and the risks of increased mortality due to comorbidities. Lung cancer trials generally exclude patients with comorbidities ... Full text Open Access Link to item Cite

The effect of non-fluoride factors on risk of dental fluorosis: evidence from rural populations of the Main Ethiopian Rift.

Journal Article Sci Total Environ · August 1, 2014 Elevated level of fluoride (F(-)) in drinking water is a well-recognized risk factor of dental fluorosis (DF). While considering optimization of region-specific standards for F(-), it is reasonable, however, to consider how local diet, water sourcing pract ... Full text Open Access Link to item Cite

QED radiative effects in the processes of exclusive photon electroproduction from polarized protons with the next-to-leading accuracy

Journal Article Physical Review D Particles Fields Gravitation and Cosmology · August 1, 2014 Radiative effects in the electroproduction of photons in polarized ep scattering are calculated with next-to-leading-order accuracy. The contributions of loops and two-photon emission are presented in analytical form. The covariant approach of Bardin and S ... Full text Open Access Cite

Exploring the association between melanoma and glioma risks.

Journal Article Annals of epidemiology · June 2014 PurposeGliomas are one of the most fatal malignancies, with largely unknown etiology. This study examines a possible connection between glioma and melanoma, which might provide insight into gliomas' etiology.MethodsUsing data provided by ... Full text Open Access Cite

Preoperative CYP2D6 metabolism-dependent β-blocker use and mortality after coronary artery bypass grafting surgery.

Journal Article J Thorac Cardiovasc Surg · April 2014 OBJECTIVE: Recently, the role of β-blockers (BBs) in reducing perioperative mortality has been challenged. The conflicting results might have resulted from the extent of BB metabolism by the cytochrome P-450 (CYP2D6) isoenzyme. The purpose of the present s ... Full text Open Access Link to item Cite

Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality.

Journal Article Int J Chron Obstruct Pulmon Dis · 2014 BACKGROUND: The respiratory tract is a major target of exposure to air pollutants, and respiratory diseases are associated with both short- and long-term exposures. We hypothesized that improved air quality in North Carolina was associated with reduced rat ... Full text Open Access Link to item Cite

Joint Analyses of Longitudinal and Time-to-Event Data in Research on Aging: Implications for Predicting Health and Survival.

Journal Article Frontiers in public health · January 2014 Longitudinal data on aging, health, and longevity provide a wealth of information to investigate different aspects of the processes of aging and development of diseases leading to death. Statistical methods aimed at analyses of time-to-event data jointly w ... Full text Open Access Cite

ON IDENTIFIABILITY OF MIXTURES OF INDEPENDENT DISTRIBUTION LAWS^{, .}

Journal Article ESAIM. Probability and statistics = Probabilites et statistique : P & S · January 2014 We consider representations of a joint distribution law of a family of categorical random variables (i.e., a multivariate categorical variable) as a mixture of independent distribution laws (i.e. distribution laws according to which random va ... Full text Open Access Cite

Trends and outcomes in the use of surgery and radiation for the treatment of locally advanced esophageal cancer: a propensity score adjusted analysis of the surveillance, epidemiology, and end results registry from 1998 to 2008.

Journal Article Dis Esophagus · 2014 We examined outcomes and trends in surgery and radiation use for patients with locally advanced esophageal cancer, for whom optimal treatment isn't clear. Trends in surgery and radiation for patients with T1-T3N1M0 squamous cell or adenocarcinoma of the mi ... Full text Open Access Link to item Cite

Morbidity risks among older adults with pre-existing age-related diseases.

Journal Article Exp Gerontol · December 2013 Multi-morbidity is common among older adults; however, for many aging-related diseases there is no information for U.S. elderly population on how earlier-manifested disease affects the risk of another disease manifested later during patient's lifetime. Qua ... Full text Open Access Link to item Cite

Predictive model of the treatment effect for patients with major depressive disorder

Journal Article 2013 ACM Conference on Bioinformatics Computational Biology and Biomedical Informatics ACM Bcb 2013 · November 28, 2013 The model to evaluate and predict the effectiveness of treatment of the Major Depressive Disorder (MDD) was developed and estimated using MindLinc data. The clinical global impression (CGI) scale with seven categories was used to measure the patient's stat ... Full text Open Access Cite

Visual analytics to optimize patient-population evidence delivery for personalized care

Conference 2013 ACM Conference on Bioinformatics Computational Biology and Biomedical Informatics ACM Bcb 2013 · November 28, 2013 Electronic medical records (EMR) can be used to identify cohorts of patients who are clinically comparable to an individual patient. In this paper, we describe an approach that applies visual analytics to EMR data to describe the clinical course for an ind ... Full text Open Access Cite

Recovery and survival from aging-associated diseases.

Journal Article Exp Gerontol · August 2013 OBJECTIVES: Considering disease incidence to be a main contributor to healthy lifespan of the US elderly population may lead to erroneous conclusions when recovery/long-term remission factors are underestimated. Using two Medicare-based population datasets ... Full text Open Access Link to item Cite

Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis.

Journal Article Age Ageing · July 2013 OBJECTIVES: time trends of age-adjusted incidence rates of 19 ageing-related diseases were evaluated for 1992-2005 period with the National Long Term Care Survey and the Surveillance, Epidemiology and End RESULTS Registry data both linked to Medicare data ... Full text Open Access Link to item Cite

Circulatory Diseases in the U.S. Elderly in the Linked National Long-Term Care Survey-Medicare Database: Population-Based Analysis of Incidence, Comorbidity, and Disability.

Journal Article Res Aging · July 2013 Incidence rates of acute coronary heart disease (ACHD; including myocardial infarction and angina pectoris), stroke, and heart failure (HF) were studied for their age, disability, and comorbidity patterns in the U.S. elderly population using the National L ... Full text Open Access Link to item Cite

Variability in the treatment of elderly patients with stage IIIA (N2) non-small-cell lung cancer.

Journal Article J Thorac Oncol · June 2013 INTRODUCTION: : We evaluated treatment patterns of elderly patients with stage IIIA (N2) non-small-cell lung cancer (NSCLC). METHODS: : The use of surgery, chemotherapy, and radiation for patients with stage IIIA (T1-T3N2M0) NSCLC in the Surveillance, Epid ... Full text Open Access Link to item Cite

[The mechanism of the antitumor effect of total/subtotal radiotherapy with non-tumoricidal doses of radiation].

Journal Article Voprosy onkologii · January 2013 The myelodepression at therapy for solid malignancies is considered as a mediating element of common antineoplastic activity on the basis of ability of stem cells of hemapoietic system to participate in regeneration of the various tissues of the body, incl ... Cite

Methodological aspects of studying human aging, health, and mortality

Chapter · January 1, 2013 Age trajectories of mortality rates in human populations characterize individuals’ inequality in the duration of life. Various models of mortality rates are used in the analyses of survival data in demographic and epidemiological applications aiming to ide ... Full text Cite

How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data.

Journal Article Frontiers in genetics · January 2013 Background and objectiveThe influence of genes on human lifespan is mediated by biological processes that characterize body's functioning. The age trajectories of these processes contain important information about mechanisms linking aging, health ... Full text Open Access Cite

How the quality of GWAS of human lifespan and health span can be improved.

Journal Article Frontiers in genetics · January 2013 Full text Open Access Cite

Patterns of Aging-Related changes on the way to 100: An Approach to studying aging, mortality, and longevity from longitudinal data

Journal Article North American Actuarial Journal · December 1, 2012 The objective of this paper is to investigate dynamic properties of age trajectories of physiological indices and their effects on mortality risk and longevity using longitudinal data on more than 5,000 individuals collected in biennial examinations of the ... Full text Open Access Cite

Does surgery improve outcomes for esophageal squamous cell carcinoma? An analysis using the surveillance epidemiology and end results registry from 1998 to 2008.

Journal Article J Am Coll Surg · November 2012 BACKGROUND: We examined survival associated with locally advanced esophageal squamous cell cancer (SCC) to evaluate if treatment without surgery could be considered adequate. STUDY DESIGN: Patients in the Surveillance, Epidemiology and End Results Registry ... Full text Open Access Link to item Cite

Is there a role for simultaneous hepatic and colorectal resections? A contemporary view from NSQIP.

Journal Article Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · November 2012 IntroductionThe optimal timing of primary and metastatic tumor management in patients with synchronous hepatic colorectal metastases remains controversial. We aimed to compare perioperative outcomes of simultaneous colorectal/liver resection (SCLR ... Full text Open Access Cite

Monte Carlo generator ELRADGEN 2.0 for simulation of radiative events in elastic ep-scattering of polarized particles

Journal Article Computer Physics Communications · July 1, 2012 The structure and algorithms of the Monte Carlo generator ELRADGEN 2.0 designed to simulate radiative events in polarized ep-scattering are presented. The full set of analytical expressions for the QED radiative corrections is presented and discussed in de ... Full text Open Access Cite

Modeling longitudinal data on health aging and life span

Journal Article Physics of Life Reviews · June 1, 2012 We address comments from the three discussants of our paper, paying particular attention to the properties of our model likely to be of interest in new applications to complex dynamic systems. © 2012 Elsevier B.V. ... Full text Open Access Cite

The quadratic hazard model for analyzing longitudinal data on aging, health, and the life span.

Journal Article Physics of life reviews · June 2012 A better understanding of processes and mechanisms linking human aging with changes in health status and survival requires methods capable of analyzing new data that take into account knowledge about these processes accumulated in the field. In this paper, ... Full text Open Access Cite

Adjuvant radiotherapy in the treatment of invasive intraductal papillary mucinous neoplasm of the pancreas: an analysis of the surveillance, epidemiology, and end results registry.

Journal Article Ann Surg Oncol · April 2012 BACKGROUND: Management and outcomes of patients with invasive intraductal papillary mucinous neoplasm (IPMN) of the pancreas are not well established. We investigated whether adjuvant radiotherapy (RT) improved cancer-specific survival (CSS) and overall su ... Full text Open Access Link to item Cite

Radiative effects in the processes of exclusive photon electroproduction from polarized protons

Journal Article Physical Review D Particles Fields Gravitation and Cosmology · March 28, 2012 Radiative effects in the electroproduction of photons in polarized ep scattering are calculated in the leading log approximation and analyzed numerically for kinematical conditions of current measurement at Jefferson Lab. Radiative corrections to the cross ... Full text Open Access Cite

New stochastic carcinogenesis model with covariates: an approach involving intracellular barrier mechanisms.

Journal Article Math Biosci · March 2012 In this paper we present a new multiple-pathway stochastic model of carcinogenesis with potential of predicting individual incidence risks on the basis of biomedical measurements. The model incorporates the concept of intracellular barrier mechanisms in wh ... Full text Open Access Link to item Cite

Age patterns of incidence of geriatric disease in the U.S. elderly population: Medicare-based analysis.

Journal Article J Am Geriatr Soc · February 2012 OBJECTIVES: To use the Medicare Files of Service Use (MFSU) to evaluate patterns in the incidence of aging-related diseases in the U.S. elderly population. DESIGN: Age-specific incidence rates of 19 aging-related diseases were evaluated using the National ... Full text Open Access Link to item Cite

Transitional probability-based model for HPV clearance in HIV-1-positive adolescent females.

Journal Article PLoS One · 2012 BACKGROUND: HIV-1-positive patients clear the human papillomavirus (HPV) infection less frequently than HIV-1-negative. Datasets for estimating HPV clearance probability often have irregular measurements of HPV status and risk factors. A new transitional p ... Full text Open Access Link to item Cite

Evaluating the number of stages in development of squamous cell and adenocarcinomas across cancer sites using human population-based cancer modeling.

Journal Article PLoS One · 2012 BACKGROUND: Adenocarcinomas (ACs) and squamous cell carcinomas (SCCs) differ by clinical and molecular characteristics. We evaluated the characteristics of carcinogenesis by modeling the age patterns of incidence rates of ACs and SCCs of various organs to ... Full text Open Access Link to item Cite

Joint analysis of health histories, physiological state, and survival

Journal Article Mathematical Population Studies · December 1, 2011 Data on individual health histories, age trajectories of physiological or biological variables, and mortality allow for the study of the joint evolution of health and physiological states and their effects on mortality. Individual health and physiological ... Full text Open Access Cite

What can we learn from the age- and race/ethnicity- specific rates of inflammatory breast carcinoma?

Journal Article Breast Cancer Res Treat · November 2011 Inflammatory Breast Carcinoma (IBC), the most aggressive type of breast tumor with unique clinicopathological presentation, is hypothesized to have distinct etiology with a socioeconomic status (SES) component. Using the Surveillance, Epidemiology and End ... Full text Link to item Cite

Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms.

Journal Article Breast Cancer Res Treat · July 2011 The observed bimodal patterns of breast cancer incidence in the U.S. suggested that breast cancer may be viewed as more than one biological entity. We studied the factors potentially contributing to this phenomenon, specifically focusing on how disease het ... Full text Open Access Link to item Cite

Trade-off in the effects of the apolipoprotein E polymorphism on the ages at onset of CVD and cancer influences human lifespan.

Journal Article Aging cell · June 2011 Progress in unraveling the genetic origins of healthy aging is tempered, in part, by a lack of replication of effects, which is often considered a signature of false-positive findings. We convincingly demonstrate that the lack of genetic effects on an agin ... Full text Open Access Cite

Modeling hematopoietic system response caused by chronic exposure to ionizing radiation.

Journal Article Radiation and environmental biophysics · May 2011 A new model of the hematopoietic system response in humans chronically exposed to ionizing radiation describes the dynamics of the hematopoietic stem cell compartment as well as the dynamics of each of the four blood cell types (lymphocytes, neutrophiles, ... Full text Open Access Cite

Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data.

Journal Article Biogerontology · April 2011 Small sample size of genetic data is often a limiting factor for desirable accuracy of estimated genetic effects on age-specific risks and survival. Longitudinal non-genetic data containing information on survival or disease onsets of study participants fo ... Full text Open Access Cite

Age trajectories of physiological indices in relation to healthy life course.

Journal Article Mechanisms of ageing and development · March 2011 We analysed relationship between the risk of onset of "unhealthy life" (defined as the onset of cancer, cardiovascular diseases, or diabetes) and longitudinal changes in body mass index, diastolic blood pressure, hematocrit, pulse pressure, pulse rate, and ... Full text Open Access Cite

Medical cost trajectories and onsets of cancer and noncancer diseases in US elderly population.

Journal Article Comput Math Methods Med · 2011 Time trajectories of medical costs-associated with onset of twelve aging-related cancer and chronic noncancer diseases were analyzed using the National Long-Term Care Survey data linked to Medicare Service Use files. A special procedure for selecting indiv ... Full text Open Access Link to item Cite

Long-term cellular effects in humans chronically exposed to ionizing radiation.

Conference Health physics · September 2010 The aim of the study was to investigate hematopoietic injury and recovery in residents of the Techa riverside villages who had been chronically exposed to radiation as a result of the activities of the Mayak Nuclear Facility, and evaluate late effects from ... Full text Cite

Early hematopoietic effects of chronic radiation exposure in humans.

Journal Article Health physics · September 2010 The major goal of this study is to investigate and quantitatively describe the nature of the relationship between the characteristics of chronic exposure to ionizing radiation and specific patterns of hematopoiesis reduction. The study is based on about 3, ... Full text Open Access Cite

Modeling deterministic effects in hematopoietic system caused by chronic exposure to ionizing radiation in large human cohorts.

Journal Article Health physics · September 2010 A new model of the hematopoietic system for humans chronically exposed to ionizing radiation allows for quantitative description of the initial hematopoiesis inhibition and subsequent increase in the risks of late stochastic effects such as leukemia. This ... Full text Open Access Cite

Trade-offs between cancer and other diseases: do they exist and influence longevity?

Journal Article Rejuvenation research · August 2010 Relationships between aging, disease risks, and longevity are not yet well understood. For example, joint increases in cancer risk and total survival observed in many human populations and some experimental aging studies may be linked to a trade-off betwee ... Full text Open Access Cite

Exceptional survivors have lower age trajectories of blood glucose: lessons from longitudinal data.

Journal Article Biogerontology · June 2010 Exceptional survival results from complicated interplay between genetic and environmental factors. The effects of these factors on survival are mediated by the biological and physiological variables, which affect mortality risk. In this paper, we evaluated ... Full text Cite

Early hematopoiesis inhibition under chronic radiation exposure in humans.

Journal Article Radiation and environmental biophysics · May 2010 The major goal of this study was to identify and quantitatively describe the association between the characteristics of chronic (low-dose rate) exposure to (low LET) ionizing radiation and cellularity of peripheral blood cell lines. About 3,200 hemograms ( ... Full text Open Access Cite

Trends in survival and recovery from stroke: evidence from the National Long-Term Care Survey/Medicare data.

Journal Article Stroke · March 2010 Background and purposeImprovements in recovery rates may contribute to an increase in healthy life expectancy. It is unclear, however, whether such changes take place because health researchers traditionally deal with changes in incidence and surv ... Full text Cite

Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction.

Journal Article Rejuvenation research · February 2010 Multiple functions of the beta2-adrenergic receptor (ADRB2) and angiotensin-converting enzyme (ACE) genes warrant studies of their associations with aging-related phenotypes. We focus on multimarker analyses and analyses of the effects of compound genotype ... Full text Open Access Cite

[Variation of mortality risk among cancer patients and individualized therapy].

Journal Article Voprosy onkologii · January 2010 To investigate the deviation of survival curves from monotonous shape, 17 curves for 6 most common cancer sites of 87,205 patients (aged 30-89) were selected from The U.S. Surveillance, Epidemiology and End Results (SEER) Register database. The curves were ... Cite

Dynamic determinants of longevity and exceptional health.

Journal Article Curr Gerontol Geriatr Res · 2010 It is well known from epidemiology that values of indices describing physiological state in a given age may influence human morbidity and mortality risks. Studies of connection between aging and life span suggest a possibility that dynamic properties of ag ... Full text Link to item Cite

A new approach to individual prognostication of cancer development under conditions of chronic radiation exposure

Journal Article International Journal of Low Radiation · January 1, 2010 This paper describes a new approach to modelling carcinogenesis, including that induced by ionising radiation. The specific feature of the developed approach is that the model, still adhering to the mutational theory of carcinogenesis, includes parameters ... Full text Cite

Maintaining physiological state for exceptional survival: What is the normal level of blood glucose and does it change with age?

Journal Article Mechanisms of ageing and development · September 2009 The levels of blood glucose (BG) in humans tend to increase with age deviating from the norm specified for the young adults. Such elevation is often considered as a factor contributing to an increase in risks of disease and death. The proper use of interve ... Full text Cite

Genetic model for longitudinal studies of aging, health, and longevity and its potential application to incomplete data.

Journal Article Journal of theoretical biology · May 2009 Many longitudinal studies of aging collect genetic information only for a sub-sample of participants of the study. These data also do not include recent findings, new ideas and methodological concepts developed by distinct groups of researchers. The formal ... Full text Cite

Studying health histories of cancer: a new model connecting cancer incidence and survival.

Journal Article Mathematical biosciences · April 2009 The results of recent experimental and epidemiological studies provide evidence on the connection between carcinogenesis, cancer progression, and aging. Existing models, however, are traditionally focused only on one of these aspects of health deterioratio ... Full text Cite

Lowest order QED radiative corrections to five-fold differential cross section of hadron leptoproduction

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · February 9, 2009 The contribution of exclusive radiative tail to the cross section of semi-inclusive hadron leptoproduction has been calculated exactly for the first time. Although the experience of inclusive data analyses suggests us that the contribution of radiative tai ... Full text Cite

Linear latent structure analysis and modelling of multiple categorical variables

Journal Article Computational and Mathematical Methods in Medicine · January 1, 2009 Linear latent structure analysis is a new approach for investigation of population heterogeneity using high-dimensional categorical data. In this approach, the population is represented by a distribution of latent vectors, which play the role of heterogene ... Full text Cite

Trade-off between cancer and aging: what role do other diseases play? Evidence from experimental and human population studies.

Journal Article Mechanisms of ageing and development · January 2009 The potential gain in life expectancy which could result from the complete elimination of mortality from cancer in the U.S. would not exceed 3 years if one were to consider cancer independently of other causes of death. In this paper, we review evidence of ... Full text Cite

Circulatory diseases and aging

Journal Article · December 1, 2008 Age patterns of incidence rates of major circulatory diseases (CDs), their time trends, risk factors, and other characteristics capable of contributing to the debates on the role of aging in the deterioration of human health are investigated using standard ... Full text Cite

Human mortality at extreme ages: Data from the NLTCS and linked medicare records

Journal Article Mathematical Population Studies · July 1, 2008 An analysis using the 1982-1999 National Long-term Care Survey (NLTCS) linked to Medicare vital statistics data 1982-2003 focused on deaths at ages 85+ where deviations from the Gompertz mortality function are often observed. To model the complex mortality ... Full text Cite

What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data.

Journal Article Mechanisms of ageing and development · April 2008 An important feature of aging-related deterioration in human health is the decline in organisms' resistance to stresses, which contributes to an increase in morbidity and mortality risks. In human longitudinal studies of aging, such a decline is not measur ... Full text Cite

Model of hidden heterogeneity in longitudinal data.

Journal Article Theoretical population biology · February 2008 Variables measured in longitudinal studies of aging and longevity do not exhaust the list of all factors affecting health and mortality transitions. Unobserved factors generate hidden variability in susceptibility to diseases and death in populations and i ... Full text Cite

Body mass index and nine-year mortality in disabled and nondisabled older U.S. individuals.

Journal Article Journal of the American Geriatrics Society · January 2008 ObjectivesTo investigate the relationship between body mass index (BMI) and 9-year mortality in older (> or = 65) Americans with and without disability.DesignCohort study.SettingThe unique disability-focused National Long Term Ca ... Full text Cite

Accelerated accumulation of health deficits as a characteristic of aging.

Journal Article Experimental gerontology · October 2007 Cross-sectional analyses show that an index of aging-associated health/well-being deficits, called the "frailty index", can characterize the aging process in humans. This study provides support for such characterization from a longitudinal analysis of the ... Full text Cite

Stochastic model for analysis of longitudinal data on aging and mortality.

Journal Article Mathematical biosciences · August 2007 Aging-related changes in a human organism follow dynamic regularities, which contribute to the observed age patterns of incidence and mortality curves. An organism's 'optimal' (normal) physiological state changes with age, affecting the values of risks of ... Full text Cite

Cumulative index of health deficiencies as a characteristic of long life.

Journal Article Journal of the American Geriatrics Society · June 2007 ObjectivesTo describe the accumulation of aging-associated health disorders using a cumulative measure known as a frailty index (FI) and to evaluate its ability to differentiate long- and short-life phenotypes as well as the FI's connection to agi ... Full text Cite

Health decline, aging and mortality: how are they related?

Journal Article Biogerontology · June 2007 The deterioration of human health with age is manifested in changes of thousands of physiological and biological variables. The contribution of some of such changes to the mortality risk may be small and cannot be reliably detected by existing statistical ... Full text Cite

Health-based population forecasting: effects of smoking on mortality and fertility.

Journal Article Risk Anal · April 2007 A microsimulation model, allowing one to forecast short- and long-term population changes conditional on the prevalence of a risk factor in a population, is presented. In this model, population changes result from the aggregation of changes in individual e ... Full text Link to item Cite

Cumulative index of health disorders as an indicator of aging-associated processes in the elderly: results from analyses of the National Long Term Care Survey.

Journal Article Mechanisms of ageing and development · March 2007 BackgroundWe employ an approach based on the elaborated frailty index (FI), which is capable of taking into account variables with mild effect on the aging, health and survival outcomes, and investigate the connections between the FI, chronologica ... Full text Cite

Cumulative index of elderly disorders and its dynamic contribution to mortality and longevity.

Journal Article Rejuvenation research · March 2007 The composite index constructed from longitudinal survey data as the level of deficits accumulated by an individual (frailty index) captures important systemic aspects of deterioration in a human organism, and is an attractive candidate for studying determ ... Full text Cite

Linear latent structure analysis: Mixture distribution models with linear constraints

Journal Article Statistical Methodology · January 1, 2007 A new method for analyzing high-dimensional categorical data, Linear Latent Structure (LLS) analysis, is presented. LLS models belong to the family of latent structure models, which are mixture distribution models constrained to satisfy the local independe ... Full text Cite

Insights on aging and exceptional longevity from longitudinal data: novel findings from the Framingham Heart Study.

Journal Article Age (Dordrecht, Netherlands) · December 2006 Age trajectories of physiological indices contain important information about aging-related changes in the human organism and therefore may help us understand human longevity. The goal of this study is to investigate whether shapes of such trajectories ear ... Full text Cite

Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data.

Journal Article Mechanisms of ageing and development · November 2006 BackgroundAn index of age-associated health/well-being disorders (deficits), called the "frailty index" (FI), appears to be a promising characteristic to capture dynamic variability in aging manifestations among age-peers. In this study we provide ... Full text Cite

Population models for the health effects of ionizing radiation.

Journal Article Radiats Biol Radioecol · 2006 In this paper we review recently-developed extension frailty, quadratic hazard, stochastic process, microsimulation, and linear latent structure models, which have the potential to describe the health effects of human populations exposed to ionizing radiat ... Link to item Cite

Modeling the effects of biologically incorporated radionuclides and chronic low-dose ionizing radiation exposure on both cancer and chronic non-cancer diseases.

Journal Article Radiats Biol Radioecol · 2006 Efforts to model the health effects of low-dose ionizing radiation (IR) have often focused on cancer. Meanwhile, significant evidence links IR and age-associated non-cancer diseases. Modeling of such complex processes, which are not currently well understo ... Link to item Cite

Endothelial progenitor cell therapy for atherosclerosis: the philosopher's stone for an aging population?

Journal Article Sci Aging Knowledge Environ · June 22, 2005 Much of the increased risk for atherosclerosis progression with age may be a result of age-related declines in the capacity of precursor cells to repair damage in the arterial endothelium. To estimate the impact of progenitor cell therapy for atheroscleros ... Full text Link to item Cite

Life tables with covariates: Dynamic model for nonlinear analysis of longitudinal data

Journal Article Mathematical Population Studies · April 1, 2005 Life table models based on nonlinear dynamics of risk factors are developed using stochastic differential equations for individual changes and on the resulting Fokker-Planck equation to describe population changes. Central to the model is a microsimulation ... Full text Cite

Risk of thyroid cancer after irradiation in children and adults

Journal Article Current Oncology · January 1, 2005 Cite

The effect of the organisms' body size and energy reserves in models for population dynamics

Journal Article Journal of Biological Systems · December 1, 2004 We present two models suitable for describing dynamics of a population of unicellular organisms residing in chemostat. These models are based on biologically motivated Dynamic Energy Budget (DEB) theory and take into account the dynamics of mean energy res ... Full text Cite

Demographic analysis and modeling of human populations exposed to ionizing radiation.

Journal Article Frontiers in bioscience : a journal and virtual library · September 2004 The health effects of ionizing radiation on human populations are often analyzed using epidemiological statistical methods. Because of the complexity of the health consequences of ionizing radiation and the prolonged period during which the consequences em ... Full text Cite

QED correction to asymmetry for polarized ep scattering from the method of electron structure functions

Journal Article Journal of Experimental and Theoretical Physics · March 1, 2004 The electron structure function method is applied to calculate model-independent QED radiative corrections to the asymmetry of electron-proton scattering. Representations for both spin-independent and spin-dependent parts of the cross section are derived. ... Full text Cite

Modeling nonlinear effects in longitudinal survival data: implications for the physiological dynamics of biological systems.

Journal Article Frontiers in bioscience : a journal and virtual library · January 2004 Despite the wealth of longitudinal data on the health dynamics of human populations, information on covariates (risk factors) changes in those studies has not been systematically and fully exploited. In this work we use the 46-year follow-up of the Framing ... Full text Cite

QED correction to asymmetry for polarized ep-scattering from the method of electron structure functions

Journal Article Zhurnal Eksperimental Noj I Teoreticheskoj Fiziki · January 1, 2004 Cite

Radiative correction to the transferred polarization in elastic electron-proton scattering

Journal Article Physical Review D · December 1, 2002 Using a method of electron structure functions, we calculated a model independent radiative correction to the recoil proton polarization for elastic electron-proton scattering. Explicit expressions for the recoil proton polarization are represented as a co ... Full text Cite

QED radiative corrections in processes of exclusive pion electroproduction

Journal Article Physical Review D Particles Fields Gravitation and Cosmology · January 1, 2002 A formalism for radiative correction (RC) calculation in exclusive pion electroproduction on the proton is presented. A FORTRAN code EXCLURAD is developed for the RC procedure. The numerical analysis is done in the kinematics of current Jefferson Lab exper ... Full text Cite

QED effects of higher orders in DIS

Journal Article Physics of Particles and Nuclei · December 1, 2001 The present status of the theoretical description of the deep inelastic scattering of leptons off protons with account for radiative corrections (RCs) in the leading and next-to-leading approximations are reviewed. For the process ep → epγ along with RC co ... Cite

Model independent radiative corrections in processes of polarized electron-nucleon elastic scattering

Journal Article Physical Review D · December 1, 2001 Explicit formulas for radiative correction (RC) calculations for elastic ep scattering are presented. Two typical measurements of polarization observables, such as beam-target asymmetry or recoil proton polarization, are considered. The possibilities of ta ... Full text Cite

Radiative corrections to polarized inelastic scattering in the coincidence setup

Journal Article Zhurnal Eksperimental Noj I Teoreticheskoj Fiziki · December 1, 2001 We completely analyze the model-independent leading radiative corrections to the cross-section and polarization observables in the semi-inclusive deep-inelastic electron-nucleus scattering with the detection of a proton and the scattered electron in coinci ... Cite

Single-spin asymmetry in deeply virtual Compton scattering: Fragmentation region of polarized lepton

Journal Article Physical Review D · November 1, 2001 For the kinematical region when a hard photon is emitted predominantly close to the direction of motion of a longitudinally polarized initial electron and relatively small momentum is transferred to a proton we calculate the azimuthal asymmetry of photon e ... Cite

Single-spin asymmetry in deeply virtual Compton scattering: Fragmentation region of polarized lepton

QED radiative corrections to asymmetries of elastic ep-scattering in hadronic variables

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · August 16, 2001 Compact analytical formulae for QED radiative corrections in the processes of elastic e-p scattering are obtained in the case when kinematic variables are reconstructed from the recoil proton momentum measured. Numerical analysis is presented under kinemat ... Full text Cite

Radiative corrections to polarized inelastic scattering in the coincidence setup

Journal Article Journal of Experimental and Theoretical Physics · January 1, 2001 We completely analyze the model-independent leading radiative corrections to the cross section and polarization observables in the semi-inclusive deep-inelastic electron-nucleus scattering with the detection of a proton and the scattered electron in coinci ... Full text Cite

Hadron formation in deep-inelastic positron scattering in a nuclear environment

Journal Article European Physical Journal C · January 1, 2001 The influence of the nuclear medium on the production of charged hadrons in semi-inclusive deep-inelastic scattering has been studied by the HERMES experiment at DESY using a 27.5 GeV positron beam. The differential multiplicity of charged hadrons and iden ... Full text Cite

The Q2-dependence of the generalised Gerasimov-Drell-Hearn integral for the proton

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · November 23, 2000 The dependence on Q2 (the negative square of the 4-momentum of the exchanged virtual photon) of the generalised Gerasimov-Drell-Hearn integral for the proton has been measured in the range 1.2 GeV2 < Q2 < 12 GeV2 ... Full text Cite

Radiative tail from the quasielastic peak in deep inelastic scattering of polarized leptons off polarized 3He

Journal Article Journal of Physics G Nuclear and Particle Physics · September 1, 2000 The contribution of the radiative tail from the quasielastic peak to low-order radiative correction to deep inelastic scattering of polarized leptons by polarized 3He is calculated within the sum-rules formalism and y-scaling hypothesis. A numer ... Full text Cite

QED radiative correction to spin-density matrix elements in exclusive vector meson production

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · February 17, 2000 QED radiative effects are considered in the case of the measurement of spin-density matrix elements of diffractive ρ-meson electroproduction. Large radiative correction for r00/5 is found in the kinematics of collider experiments at H ... Full text Cite

Exclusive leptoproduction of ρ0 mesons from hydrogen at intermediate virtual photon energies

Journal Article European Physical Journal C · January 1, 2000 Measurements of the cross section for exclusive virtual-photoproduction of ρ0 mesons from hydrogen are reported. The data were collected by the HERMES experiment using 27.5 GeV positrons incident on a hydrogen gas target in the HERA storage ring ... Full text Cite

Radiative corrections to the structure functions and sum rules in polarized dis

Conference Czechoslovak Journal of Physics · January 1, 2000 The one-loop NLO radiative corrections (RC) to the observables in polarized DIS using assumption that a quark is an essential massive particle are considered. If compared with classical QCD formulae the obtained results are identical for the unpolarized an ... Full text Cite

Triplet production by linearly polarized photons

Journal Article Physical Review A Atomic Molecular and Optical Physics · January 1, 2000 The process of electron-positron pair production by linearly polarized photons may be used as a polarimeter to perform mobile measurement of linear photon polarization. In the limit of high photon energies ω the distributions of the recoil-electron momentu ... Cite

Triplet production by linearly polarized photons

QED correction to the radiative tail from the elastic peak in deep inelastic scattering

Journal Article Physical Review D - Particles, Fields, Gravitation and Cosmology · January 1, 2000 We calculate the deep inelastic scattering (DIS) cross section under kinematical requirements when a final hadron state is a single proton. The process in the lowest order is known as the radiative tail from the elastic peak. We take into account the corre ... Full text Cite

Nuclear effects on R=o(L)/o(T) in deep inelastic scattering

Journal Article Phys. Lett. B · 2000 Cite

Radiative effects in processes of diffractive vector meson electroproduction

Journal Article European Physical Journal C · January 1, 1999 The electromagnetic radiative correction to the cross section of the vector meson electroproduction is calculated. Explicit covariant formulae for the observed cross section are obtained. The dependence of the radiative correction on the experimental resol ... Full text Cite

Radiative effects in the processes of hadron electroproduction

Journal Article European Physical Journal C · January 1, 1999 An approach to calculate radiative corrections to the unpolarized cross section of semi-inclusive electroproduction is developed. Explicit formulae for the lowest order QED radiative correction are presented. A detailed numerical analysis is performed with ... Full text Cite

Current-target correlations as a probe of ΔG / G in polarized deep inelastic scattering

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · January 1, 1999 The measurement of the polarized gluon distribution function ΔG / G using current-target correlations in the Breit frame of deep inelastic scattering is proposed. The approach is illustrated using a Monte Carlo simulation of polarized ep-collisions for HER ... Full text Cite

Single-spin asymmetries for small-angle pion production in high-energy hadron collisions

Journal Article European Physical Journal C · January 1, 1999 Within the framework of a simple model, we study single-spin asymmetries for pion production in hadron-hadron collisions at high energies with one hadron polarized. The asymmetries are generated via a mechanism of final-(initial-) state interactions. For p ... Full text Cite

Flavor decomposition of the polarized quark distributions in the nucleon from inclusive and semi-inclusive deep-inelastic scattering

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · January 1, 1999 Spin asymmetries of semi-inclusive cross sections for the production of positively and negatively charged hadrons have been measured in deep-inelastic scattering of polarized positrons on polarized hydrogen and He targets, in the kinematic range 0.023 < x ... Full text Cite

Observation of a coherence length effect in exclusive ρ0 Electroproduction

Journal Article Physical Review Letters · January 1, 1999 Exclusive incoherent electroproduction of the ρ0(770) meson from 1H, 2H, 3He, and 14N targets has been studied by the HERMES experiment at squared four-momentum transfer Q2 > 0.4GeV2 Full text Cite

Determination of the deep inelastic contribution to the generalised Gerasimov-Drell-Hearn integral for the proton and neutron

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · December 24, 1998 The virtual photon absorption cross section differences [σ1/2 - σ3/2] for the proton and neutron have been determined from measurements of polarised cross section asymmetries in deep inelastic scattering of 27.5 GeV longitudinally pol ... Full text Cite

Measurement of the proton spin structure function g1p with a pure hydrogen target

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · December 3, 1998 A measurement of the proton spin structure function g1p(x,Q2) in deep-inelastic scattering is presented. The data were taken with the 27.6 GeV longitudinally polarised positron beam at HERA incident on a longitudinally pola ... Full text Cite

The systematic uncertainties in measurements of the spin-dependent structure function gn1 with 3He target due to radiative correction procedure

Journal Article Journal of Physics G Nuclear and Particle Physics · December 1, 1998 Two possible schemes of the radiative correction procedure are discussed. The sources of the systematic uncertainties due to the radiative correction procedure in the measurements of the structure function gn1 with 3He targ ... Full text Cite

Approximate calculation of first- and second-order radiative corrections to deep-inelastic scattering on polarized nuclei

Journal Article Physics of Atomic Nuclei · December 1, 1998 Model-independent radiative corrections of orders α, αL, and α2L2 to the lepton current for the deep-inelastic scattering of polarized leptons on light polarized nuclei have been obtained. The computational method employed is briefly ... Cite

Radiative electroweak effects in deep inelastic scattering of polarized leptons by polarized nucleons

Journal Article Journal of Physics G Nuclear and Particle Physics · November 1, 1998 The one-loop electroweak radiative correction of the lowest order to lepton current for deep inelastic scattering of longitudinally polarized leptons by polarized nucleons is obtained in a model-independent way. Detailed numerical analysis within the kinem ... Full text Cite

Compton tensor with heavy photon in the case of a longitudinally polarized fermion

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · July 23, 1998 The matrix element squared for Compton scattering of a heavy photon on a longitudinally polarized electron is calculated. Assuming that all kinematical invariants and the invariant mass of the heavy photon are large in comparison with the electron mass, th ... Full text Cite

Extraction of asymmetries and spin-dependent structure functions from cross-sections of polarised lepton-nucleon interactions

Journal Article Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment · June 21, 1998 A new method to extract asymmetries and spin-dependent structure functions is proposed. The method is based on the exact formulae for differences of cross-sections of deep inelastic scattering of polarised leptons on polarised nucleons with different orien ... Full text Cite

Flavor asymmetry of the light quark sea from semi-inclusive deep-inelastic scattering

Journal Article Physical Review Letters · January 1, 1998 The flavor asymmetry of the light quark sea of the nucleon is determined in the kinematic range 0.02 < x < 0.3 and 1 < Q2 < 10GeV2 for the first time from semi-inclusive deep-inelastic scattering. The quantity [d¯(x)- ¯u(x)]/[u(x)-d(x ... Full text Cite

POLRAD 2.0 code for the radiative corrections to DIS of polarized particles

Conference Acta Physica Polonica B · December 1, 1997 Physics of the radiative corrections to deep inelastic inclusive and semi-inclusive experiments of polarized particles is discussed. The new version of FORTRAN code POLRAD 2.0 is presented. Current status is described. ... Cite

Measurement of the neutron spin structure function gn1 with a polarized 3He internal target

Journal Article Physics Letters Section B Nuclear Elementary Particle and High Energy Physics · July 10, 1997 Results are reported from the HERMES experiment at HERA on a measurement of the neutron spin structure function gn1(x, Q2) in deep inelastic scattering using 27.5 GeV longitudinally polarized positrons incident on a polariz ... Full text Cite

POLRAD 2.0. FORTRAN code for the radiative corrections calculation to deep inelastic scattering of polarized particles

Journal Article Computer Physics Communications · January 1, 1997 The FORTRAN code POLRAD 2.0 for radiative correction calculation in inclusive and semi-inclusive deep inelastic scattering of polarized leptons by polarized nucleons and nuclei is described. Its theoretical basis, structure and algorithms are discussed in ... Full text Cite

Radiative effects in deep inelastic scattering of polarized leptons by polarized light nuclei

Journal Article Journal of Physics G Nuclear and Particle Physics · December 1, 1994 Principal contributions to QED radiative effects in deep inelastic scattering (DIS) of polarized leptons by polarized targets (H,D,3He) are investigated both on the Born level and taking into account radiative corrections (RC). Scattering in the ... Full text Cite

The radiative tail from elastic peak to deep inelastic scattering of polarized particles within standard electroweak theory

Journal Article Journal of Physics G Nuclear and Particle Physics · December 1, 1992 The authors obtain the formulae for the invariant inclusive cross section of the elastic radiative tail and other observables which shall be measured in forthcoming lepton-nucleon experiments. Taking into account the parameters of these experiments a reali ... Full text Cite