Scholars@Duke
Tracy Anne Jaffe

Tracy Anne Jaffe

Professor of Radiology
Radiology, Abdominal Imaging
jaffe002@mc.duke.edu
Box 3808 Med Ctr, Durham, NC
Dept of Radiology, Durham, NC

Selected Publications

A Faster Prostate MRI: Comparing a Novel Denoised, Single-Average T2 Sequence to the Conventional Multiaverage T2 Sequence Regarding Lesion Detection and PI-RADS Score Assessment.

Journal Article J Magn Reson Imaging · August 2023 BACKGROUND: The T2 w sequence is a standard component of a prostate MRI examination; however, it is time-consuming, requiring multiple signal averages to achieve acceptable image quality. PURPOSE/HYPOTHESIS: To determine whether a denoised, single-average ... Full text Link to item Cite

Comparing Survival Outcomes of Patients With LI-RADS-M Hepatocellular Carcinomas and Intrahepatic Cholangiocarcinomas.

Journal Article J Magn Reson Imaging · January 2023 BACKGROUND: There is a sparsity of data evaluating outcomes of patients with Liver Imaging Reporting and Data System (LI-RADS) (LR)-M lesions. PURPOSE: To compare overall survival (OS) and progression free survival (PFS) between hepatocellular carcinoma (H ... Full text Link to item Cite

Clinical and imaging predictors of the natural course of bland portal vein thrombus in cirrhotic patients.

Journal Article Abdom Radiol (NY) · November 2022 BACKGROUND: Portal vein thrombus (PVT) in cirrhotic patients is associated with worsening portal hypertension, leads to increased complexity of necessary interventions such as transjugular liver portosystemic shunt or liver transplantation, and is associat ... Full text Link to item Cite

Electronic Health Record Closed-Loop Communication Program for Unexpected Nonemergent Findings.

Journal Article Radiology · October 2021 Background Reliance on examination reporting of unexpected imaging findings does not ensure receipt of findings or appropriate follow-up. A closed-loop communication system should include provider and patient notifications and be auditable through the elec ... Full text Link to item Cite

Intravascular Ultrasound-Guided Transvenous Biopsy of Abdominal and Pelvic Targets Difficult to Access by Percutaneous Needle Biopsy: Technique and Initial Clinical Experience.

Journal Article J Vasc Interv Radiol · September 2021 PURPOSE: To report initial clinical experience with intravascular ultrasound (US)-guided transvenous biopsy (TVB) for perivascular target lesions in the abdomen and pelvis using side-viewing phased-array intracardiac echocardiography catheters. MATERIALS A ... Full text Link to item Cite

Optimizing Identification of Power Injectable Ports on the Scout Images for Multidetector Computed Tomography Procedures.

Journal Article J Comput Assist Tomogr · May 2021 OBJECTIVE: The objective of this study was to assess the impact of tube voltage and image display on the identification of power ports features on anterior-posterior scout images to inform optimal workflow for multidetector computed tomography (MDCT) exami ... Full text Link to item Cite

Automated Structured Reporting for Thyroid Ultrasound: Effect on Reporting Errors and Efficiency.

Journal Article J Am Coll Radiol · February 2021 PURPOSE: To compare the effectiveness of different reporting templates using the ACR Thyroid Imaging Reporting and Data System (TI-RADS) for thyroid ultrasound. METHODS: In this retrospective study, four radiologists implemented ACR TI-RADS while dictating ... Full text Open Access Link to item Cite

MR Enterography of Complicated Crohn Disease: Stricturing and Penetrating Disease.

Journal Article Top Magn Reson Imaging · February 1, 2021 Stricturing and penetrating disease are complications of Crohn disease (CD) that significantly affect patient outcomes. Careful evaluation for such complications is critical to the interpretation of magnetic resonance enterography. This manuscript outlines ... Full text Link to item Cite

LI-RADS ancillary feature prediction of longitudinal category changes in LR-3 observations: an exploratory study.

Journal Article Abdom Radiol (NY) · October 2020 PURPOSE: To determine whether LI-RADS ancillary features predict longitudinal LR-3 observation category changes. MATERIALS AND METHODS: This exploratory, retrospective, single-center study with an independent reading center included patients who underwent ... Full text Link to item Cite

Ultrasound-guided non-targeted liver core biopsy: comparison of the efficacy of two different core needle biopsy systems using an ex-vivo animal model and retrospective review of clinical experience.

Journal Article Clin Imaging · May 2020 PURPOSE: To compare the efficacy of two 18-gauge core needle biopsy systems, the Achieve® (Merit Medical) and the Marquee® (BD Bard), using an ex-vivo animal liver model and retrospective review of clinical experience. METHODS: Sixty ex-vivo liver biopsy s ... Full text Link to item Cite

Computed tomography and magnetic resonance enterography protocols and techniques: survey of the Society of Abdominal Radiology Crohn's Disease Disease-Focused Panel.

Journal Article Abdom Radiol (NY) · April 2020 PURPOSE: To survey Society of Abdominal Radiology Crohn's Disease (CD) Disease-Focused Panel (DFP) members to understand state-of-the-art CT/MR enterography (CTE/MRE) protocols and variability between institutions. METHODS: This study was determined by an ... Full text Link to item Cite

Moving Radiology Workflow to the Electronic Health Record: Quantitative and Qualitative Experience From a Large Academic Medical Center.

Journal Article Acad Radiol · February 2020 RATIONALE AND OBJECTIVES: To objectively and subjectively evaluate a large, academic radiology department's transition to electronic health record (EHR) centered workflow. MATERIALS AND METHODS: Multiple metrics were compared from before and after the move ... Full text Link to item Cite

Small Bowel Crohn Disease at CT and MR Enterography: Imaging Atlas and Glossary of Terms.

Journal Article Radiographics · 2020 Representatives from the Society of Abdominal Radiology Crohn's Disease-Focused Panel, the Society for Pediatric Radiology, the American Gastroenterological Association, and other international experts recently reported consensus recommendations for standa ... Full text Link to item Cite

Imaging-guided percutaneous thrombin injection for the treatment of iatrogenic femoral artery pseudoaneurysms.

Journal Article Abdom Radiol (NY) · March 2019 PURPOSE: To evaluate factors that may affect successful ultrasound-guided percutaneous thrombin injection of iatrogenic femoral artery pseudoaneurysms (PSA). MATERIALS AND METHODS: This was an IRB-approved, HIPAA-compliant retrospective study of 326 consec ... Full text Link to item Cite

Automated Early Identification of an Excessive Air-in-Oil X-ray Tube Artifact That Mimics Acute Cerebral Infarct.

Journal Article J Comput Assist Tomogr · 2019 PURPOSE: This study aimed to develop an automated, quantitative method to increase the likelihood of identifying and preventing such air-in-oil (AIO) artifact. METHODS: A 1-dimensional radial representation of the 2-dimensional noise power spectrum (NPS) w ... Full text Link to item Cite

Comparison of Visualization Rates of LI-RADS Version 2014 Major Features With IV Gadobenate Dimeglumine or Gadoxetate Disodium in Patients at Risk for Hepatocellular Carcinoma.

Journal Article AJR Am J Roentgenol · June 2018 OBJECTIVE: The purpose of this study is to compare visualization rates of the major features covered by Liver Imaging Reporting and Data System (LI-RADS) version 2014 in patients at risk for hepatocellular carcinoma using either gadobenate dimeglumine or g ... Full text Link to item Cite

Consensus Recommendations for Evaluation, Interpretation, and Utilization of Computed Tomography and Magnetic Resonance Enterography in Patients With Small Bowel Crohn's Disease.

Journal Article Gastroenterology · March 2018 Computed tomography and magnetic resonance enterography have become routine small bowel imaging tests to evaluate patients with established or suspected Crohn's disease, but the interpretation and use of these imaging modalities can vary widely. A shared u ... Full text Link to item Cite

Clinically Acceptable Optimized Dose Reduction in Computed Tomographic Imaging of Necrotizing Pancreatitis Using a Noise Addition Software Tool.

Journal Article J Comput Assist Tomogr · 2018 OBJECTIVE: This study aimed to determine potential radiation dose reduction of contrast-enhanced computed tomography (CECT) for imaging necrotizing pancreatitis (NP) using a noise addition tool. METHODS: Eighty-four patients were identified with at least 1 ... Full text Link to item Cite

CT Findings of Traumatic Bucket-Handle Mesenteric Injuries.

Journal Article AJR Am J Roentgenol · December 2017 OBJECTIVE: The purpose of this study is to describe a specific type of blunt traumatic mesenteric injury called a bucket-handle tear, review its varied CT appearances, and discuss the role of CT in its detection. CONCLUSION: A bucket-handle mesenteric inju ... Full text Link to item Cite

Liver imaging reporting and data system category 4 observations in MRI: Risk factors predicting upgrade to category 5.

Journal Article J Magn Reson Imaging · September 2017 PURPOSE: To identify demographic and imaging features in magnetic resonance imaging (MRI) that are associated with upgrade of Liver Imaging Reporting and Data System (LI-RADS) category 4 (LR-4) observations to category 5 (LR-5), and to assess their effects ... Full text Link to item Cite

Structured reporting of CT enterography for inflammatory bowel disease: effect on key feature reporting, accuracy across training levels, and subjective assessment of disease by referring physicians.

Journal Article Abdom Radiol (NY) · September 2017 PURPOSE: To compare the content and accuracy of structured reporting (SR) versus non-structured reporting (NSR) for computed tomographic enterography (CTE) of inflammatory bowel disease (IBD). MATERIALS AND METHODS: This IRB-approved, HIPAA-compliant, retr ... Full text Link to item Cite

Gender and Radiology Publication Productivity: An Examination of Academic Faculty From Four Health Systems in the United States.

Journal Article J Am Coll Radiol · August 2017 OBJECTIVES: To compare male and female radiology faculty publication productivity metrics at four major academic centers. MATERIALS AND METHODS: All Radiology Department faculty members at four academic medical centers from January 1, 2000, to December 31, ... Full text Link to item Cite

Intravenous Gadoxetate Disodium Administration Reduces Breath-holding Capacity in the Hepatic Arterial Phase: A Multi-Center Randomized Placebo-controlled Trial.

Journal Article Radiology · February 2017 Purpose To determine, in a multicenter double-blinded placebo-controlled trial, whether maximal hepatic arterial phase breath-holding duration is affected by gadoxetate disodium administration. Materials and Methods Institutional review board approval was ... Full text Link to item Cite

Contrast media for fluoroscopic examinations of the GI and GU tracts: current challenges and recommendations.

Journal Article Abdom Radiol (NY) · January 2017 One of the significant challenges facing radiologists who perform and interpret studies of the gastrointestinal and genitourinary systems have been periodic interruptions in the availability of barium and iodinated contrast media specially formulated for g ... Full text Link to item Cite

Structured Reporting of Magnetic Resonance Enterography for Pediatric Crohn's Disease: Effect on Key Feature Reporting and Subjective Assessment of Disease by Referring Physicians.

Journal Article Curr Probl Diagn Radiol · 2017 PURPOSE: To objectively compare the content of structured reports (SR) vs nonstructured reports (NSR) for magnetic resonance enterography (MRE) of pediatric patients with Crohn's disease, and to evaluate referring clinicians' subjective assessment of repor ... Full text Link to item Cite

Effect of a Low-Rank Denoising Algorithm on Quantitative Magnetic Resonance Imaging-Based Measures of Liver Fat and Iron.

Journal Article J Comput Assist Tomogr · 2017 PURPOSE: This study aimed to assess the effect of a low-rank denoising algorithm on quantitative magnetic resonance imaging-based measures of liver fat and iron. MATERIALS AND METHODS: This was an institutional review board-approved, Health Insurance Porta ... Full text Link to item Cite

Radiographic and endoscopic regression of metastatic gastric cancer to the colon in the setting of 5-aminosalicylic acid use.

Journal Article J Gastrointest Oncol · December 2016 Colonic metastases from gastric cancer are a rare phenomenon and sparsely reported in the literature. We report a case of a 59-year-old woman who presented with vague abdominal symptoms and initial computer tomography (CT) imaging suggestive of a colonic a ... Full text Link to item Cite

CT abdominal imaging findings in patients with sickle cell disease: acute vaso-occlusive crisis, complications, and chronic sequelae.

Journal Article Abdom Radiol (NY) · December 2016 Sickle cell disease (SCD) is the most prevalent hemoglobinopathy. Survival in patients with SCD has improved over the past few decades. These patients experience a lifetime of repeated acute pain crises, which are thought to result from sickling and microv ... Full text Link to item Cite

Diagnostic performance of MDCT in identifying closed loop small bowel obstruction.

Journal Article Abdom Radiol (NY) · July 2016 PURPOSE: To assess the diagnostic performance of MDCT in the diagnosis of closed loop small bowel obstruction. MATERIALS AND METHODS: One hundred fifty patients with CT reports including "small bowel obstruction (SBO)" between 1/30/2011 and 12/4/2012 were ... Full text Link to item Cite

Can combining triple-arterial phase acquisition with fluoroscopic triggering provide both optimal early and late hepatic arterial phase images during gadoxetic acid-enhanced MRI?

Journal Article J Magn Reson Imaging · May 2016 PURPOSE: To determine whether triple-arterial phase acquisition with fluoroscopic triggering can provide both well-timed early and late hepatic arterial phase (HAP) images more frequently than when using a fixed-time delay during gadoxetic acid-enhanced ma ... Full text Link to item Cite

Computed Tomography-Based Limb Volume Measurements for Isolated Limb Infusion in Melanoma.

Journal Article Ann Surg Oncol · April 2016 BACKGROUND: Despite advances in cross-sectional imaging, chemotherapeutic dosing for isolated limb infusion (ILI) in melanoma is currently calculated through cumbersome and potentially imprecise manual measurements. The primary objective of this study was ... Full text Link to item Cite

Image-guided percutaneous drainage: a review.

Journal Article Abdom Radiol (NY) · April 2016 Percutaneous abscess drainage (PAD) has been proven to be a safe, effective, and widely used technique for treatment of patients with intra-abdominal fluid collections. Indications for PAD are ever expanding, and most abscesses are amenable to PAD. PAD is ... Full text Link to item Cite

Acute gastrointestinal vaso-occlusive ischemia in sickle cell disease: CT imaging features and clinical outcome.

Journal Article Abdom Radiol (NY) · March 2016 PURPOSE: The purpose of this study was to determine the incidence, specific imaging features, and outcome of gastrointestinal vaso-occlusive ischemia (GVOI) in sickle cell patients undergoing CT for acute abdominal pain. METHODS: This HIPAA-compliant, IRB- ... Full text Link to item Cite

Isolated recto-sigmoid colitis: a new imaging pattern of ipilimumab-associated colitis.

Journal Article Abdom Radiol (NY) · February 2016 PURPOSE: The purpose of this study is to describe typical CT findings and distinct imaging patterns of ipilimumab-associated colitis in immunotherapeutic treatment of melanoma. MATERIALS AND METHODS: This HIPAA-compliant retrospective study included 86 pat ... Full text Link to item Cite

Magnetic resonance imaging of acute appendicitis in pregnancy: a 5-year multiinstitutional study.

Journal Article Am J Obstet Gynecol · November 2015 OBJECTIVE: The purpose of this study was to determine the diagnostic performance of magnetic resonance imaging (MRI) in the diagnosis of acute appendicitis during pregnancy in a multiinstitutional study. STUDY DESIGN: In this multicenter retrospective stud ... Full text Link to item Cite

Impact of CT in elderly patients presenting to the emergency department with acute abdominal pain.

Journal Article Abdom Imaging · October 2015 PURPOSE: The purpose of the study was to document the clinical impact of CT in elderly patients presenting to the emergency department (ED) with abdominal pain. METHODS: This retrospective IRB-approved study from 2006 to 2013 evaluated 464 patients ≥80 yea ... Full text Link to item Cite

The role of CT-guided percutaneous drainage of loculated air collections: an institutional experience.

Journal Article Abdom Imaging · October 2015 OBJECTIVE: The purpose of this study is to describe our experience with the role of CT-guided percutaneous drainage of loculated intra-abdominal collections consisting entirely of gas. MATERIALS AND METHODS: An IRB-approved retrospective study analyzing pa ... Full text Link to item Cite

Concordance of hypervascular liver nodule characterization between the organ procurement and transplant network and liver imaging reporting and data system classifications.

Journal Article J Magn Reson Imaging · August 2015 PURPOSE: To determine the rate of agreement between the Organ Procurement and Transplant Network (OPTN) and Liver Imaging Reporting and Data System (LI-RADS) classifications for hypervascular liver nodules at least 1 cm in diameter, and for patient eligibi ... Full text Link to item Cite

Management of Anticoagulant and Antiplatelet Medications in Adults Undergoing Percutaneous Interventions.

Journal Article AJR Am J Roentgenol · August 2015 OBJECTIVE: Many radiologists are unfamiliar with the new antithrombogenic medications and how to modify patient management before nonvascular percutaneous procedures performed in a radiology department. In this article, we review the indications for use, m ... Full text Link to item Cite

Image-guided percutaneous drainage vs. surgical repair of gastrointestinal anastomotic leaks: is there a difference in hospital course or hospitalization cost?

Journal Article Abdom Imaging · June 2015 PURPOSE: To identify differences in hospital course and hospitalization cost when comparing image-guided percutaneous drainage with surgical repair for gastrointestinal anastomotic leaks. MATERIALS AND METHODS: A retrospective IRB-approved search using key ... Full text Link to item Cite

Large-Bowel Obstruction in the Adult: Classic Radiographic and CT Findings, Etiology, and Mimics.

Journal Article Radiology · June 2015 Large-bowel obstruction is an abdominal emergency with high morbidity and mortality rates if left untreated. Although abdominal radiography is usually the initial imaging study performed in patients suspected of having large-bowel obstruction, it may not b ... Full text Link to item Cite

CT of Gastrointestinal Vasoocclusive Crisis Complicating Sickle Cell Disease.

Journal Article AJR Am J Roentgenol · May 2015 OBJECTIVE: The purposes of this article are to illustrate the CT appearance of gastrointestinal vasoocclusive crisis in patients with sickle cell disease (SCD), highlight potential complications, and review other conditions that may have similar findings. ... Full text Link to item Cite

Respiratory motion artifact affecting hepatic arterial phase MR imaging with gadoxetate disodium is more common in patients with a prior episode of arterial phase motion associated with gadoxetate disodium.

Journal Article Radiology · January 2015 PURPOSE: To determine, in a dual-center setting, whether patients who experience transient severe motion ( TSM transient severe motion ) in the arterial phase during gadoxetate disodium-enhanced magnetic resonance (MR) imaging are at higher risk for a subs ... Full text Link to item Cite

Graft Kidney Torsion After Simultaneous Kidney-Pancreas Transplant: Report of 2 Cases and Literature Review.

Journal Article J Comput Assist Tomogr · 2015 Torsion of an allograft kidney is an extremely rare and potentially reversible complication. Imaging diagnosis plays a crucial role because of the absence of specific clinical features. We report 2 cases in which kidney torsion after simultaneous kidney-pa ... Full text Link to item Cite

Origin, Incidence, and Management of Nongynecologic Pelvic Masses Seen on Cross-sectional Imaging.

Journal Article J Reprod Med · 2015 OBJECTIVE: To characterize the origin of nongynecologic pelvic masses. STUDY DESIGN: Using a radiology database, women who underwent transvaginal ultrasound, CT scan, or MRI for the indication of pelvic mass or pelvic fullness were identified. Demographic ... Link to item Cite

Dual-energy MDCT in hypervascular liver tumors: effect of body size on selection of the optimal monochromatic energy level.

Journal Article AJR Am J Roentgenol · December 2014 OBJECTIVE: The purpose of this article is to investigate the effect of body size on the selection of optimal monochromatic energy level for maximizing the conspicuity of hypervascular liver tumors during late hepatic arterial phase using dual-energy MDCT. ... Full text Link to item Cite

Impact of dual-energy multi-detector row CT with virtual monochromatic imaging on renal cyst pseudoenhancement: in vitro and in vivo study.

Journal Article Radiology · September 2014 PURPOSE: To investigate whether dual-energy multi-detector row computed tomography (CT) with virtual monochromatic imaging can overcome renal cyst pseudoenhancement in a phantom experiment and a clinical study. MATERIALS AND METHODS: This retrospective sin ... Full text Link to item Cite

Retrospective assessment of the utility of an iron-based agent for contrast-enhanced magnetic resonance venography in patients with endstage renal diseases.

Journal Article J Magn Reson Imaging · July 2014 PURPOSE: To compare abdominopelvic and lower extremity venous enhancement in contrast-enhanced magnetic resonance venography (ceMRV), using iron-based ferumoxytol and gadolinium-based gadofosveset. MATERIALS AND METHODS: This was a Health Insurance Portabi ... Full text Link to item Cite

Safety of an intercostal approach for imaging-guided percutaneous drainage of subdiaphragmatic abscesses.

Journal Article AJR Am J Roentgenol · June 2014 OBJECTIVE: The objective of our study was to test the hypothesis that an intercostal approach to imaging-guided percutaneous subdiaphragmatic abscess drainage is as safe as a subcostal approach. MATERIALS AND METHODS: A cohort of 258 consecutive patients w ... Full text Link to item Cite

Current opinions on medical radiation: a survey of oncologists regarding radiation exposure and dose reduction in oncology patients.

Journal Article J Am Coll Radiol · May 2014 PURPOSE: The aim of this study was to evaluate oncologists' opinions about the use of ionizing radiation in medical imaging of oncology patients. METHODS: An electronic survey was e-mailed to 2,725 oncologists at the top 50 National Cancer Institute-funded ... Full text Link to item Cite

Respiratory motion artifact affecting hepatic arterial phase imaging with gadoxetate disodium: examination recovery with a multiple arterial phase acquisition.

Journal Article Radiology · May 2014 PURPOSE: To determine whether the use of a multiple arterial phase imaging technique provides adequate image quality in patients experiencing transient severe motion (TSM) in the arterial phase on abdominal magnetic resonance (MR) images obtained with gado ... Full text Link to item Cite

Paratubal/Paraovarian Masses: A Study of Surgical and Non-Surgical Outcomes.

Journal Article Medical Journal of Obstetrics And Gynecology · January 5, 2014 Cite

A phase II trial of temsirolimus in men with castration-resistant metastatic prostate cancer.

Journal Article Clin Genitourin Cancer · December 2013 BACKGROUND: Phosphatase and tensin homologue (PTEN) loss is common in advanced prostate cancer, leading to constitutive activation of the PI3 kinase pathway. Temsirolimus blocks mammalian target of rapamycin (mTOR)/target of rapamycin complex 1 (TORC1), a ... Full text Link to item Cite

Postsurgical colon

Journal Article · November 1, 2013 Colorectal surgery is estimated to represent 28% of abdominal surgeries (Chu and Schoetz 2007). Indications for colorectal surgery include nonmalignant etiologies such as diverticular disease, volvulus, and inflammatory bowel disease as well as malignancie ... Full text Cite

Is follow-up CT imaging of the chest and abdomen necessary after preoperative neoadjuvant therapy in rectal cancer patients without evidence of metastatic disease at diagnosis?

Journal Article Colorectal Dis · November 2013 AIM: Patients with rectal cancer often undergo multiple CT scans prior to surgical resection. We propose that in patients with locally advanced rectal cancer without evidence of metastatic disease at presentation, CT imaging of the chest and abdomen after ... Full text Link to item Cite

Renal transplant imaging using magnetic resonance angiography with a nonnephrotoxic contrast agent.

Journal Article Transplantation · July 15, 2013 BACKGROUND: In renal allograft recipients presenting with graft dysfunction, it is critical to determine the patency of the transplant vasculature to guide clinical management. Conventional modalities such as Doppler ultrasound, contrast-enhanced computed ... Full text Link to item Cite

The incarcerated uterus: a review of MRI and ultrasound imaging appearances.

Journal Article AJR Am J Roentgenol · July 2013 OBJECTIVE: The objective of this article is to review the MRI and ultrasound appearances of incarcerated uterus. CONCLUSION: Incarcerated uterus is a rare but serious complication of pregnancy in which the gravid uterus becomes trapped in the posterior pel ... Full text Link to item Cite

Activity of single-agent bevacizumab in patients with metastatic renal cell carcinoma previously treated with vascular endothelial growth factor tyrosine kinase inhibitors.

Journal Article Clin Genitourin Cancer · March 2013 PURPOSE: The activity of systemic agents after progression when using vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibition (TKI) and mammalian target of rapamycin (mTOR) inhibition in patients with metastatic renal cell carcinoma ... Full text Link to item Cite

A phase II trial of temsirolimus in men with castration-resistant metastatic prostate cancer.

Conference Journal of Clinical Oncology · February 20, 2013 105 Background: PTEN loss is common in advanced prostate cancer, leading to constitutive activation of the PI3 Kinase pathway. Temsirolimus blocks mTOR/TORC1, a key signaling node in this pathway; its activity in men with advance ... Full text Cite

Hepatocellular carcinoma in a North American population: does hepatobiliary MR imaging with Gd-EOB-DTPA improve sensitivity and confidence for diagnosis?

Journal Article J Magn Reson Imaging · February 2013 PURPOSE: To evaluate the value of hepatobiliary phase imaging for detection and characterization of hepatocellular carcinoma (HCC) in liver MRI with Gd-EOB-DTPA, in a North American population. MATERIALS AND METHODS: One hundred MRI examinations performed ... Full text Link to item Cite

Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose?

Journal Article J Comput Assist Tomogr · 2013 OBJECTIVE: The objectives of this study were to explore utilization of multi-detector row computed tomography (MDCT) in screening for hepatocellular carcinoma (HCC) and to modify a liver CT protocol with a goal of dose reduction. METHODS: An electronic mai ... Full text Link to item Cite

Can the localization of primary colonic tumors be improved by staging CT without specific bowel preparation compared to optical colonoscopy?

Journal Article Eur J Radiol · October 2012 OBJECTIVES: To investigate the ability of staging computed tomography (CT) without bowel preparation to accurately localize colonic tumors compared to optical colonoscopy. METHODS: The local institutional review board approved this retrospective and HIPAA- ... Full text Link to item Cite

Radiation dose reduction in abdominal computed tomography during the late hepatic arterial phase using a model-based iterative reconstruction algorithm: how low can we go?

Journal Article Invest Radiol · August 2012 OBJECTIVE: The aim of this study was to compare the image quality of abdominal computed tomography scans in an anthropomorphic phantom acquired at different radiation dose levels where each raw data set is reconstructed with both a standard convolution fil ... Full text Link to item Cite

Mandated radiologist-performed electronic order entry: effect on CT oral contrast administration.

Journal Article AJR Am J Roentgenol · March 2012 OBJECTIVE: The purpose of this study was to determine whether radiologist-performed electronic order entry affects use of oral contrast material for CT. Contrast media have been classified as medications by The Joint Commission, which necessitates a physic ... Full text Link to item Cite

Activity of single-agent bevacizumab (B) in patients with metastatic renal cell carcinoma (RCC) previously treated with VEGF- and mTOR-based therapies.

Journal Article J Clin Oncol · February 10, 2012 435 Background: Given a lack of clinical information on therapeutic efficacy of agents following progression after vascular endothelial growth factor (VEGF) tyrosine kinase inhibition (TKI) and mammalian target of rapamycin (mTOR) inhibition in metastatic ... Full text Link to item Cite

Diagnostic accuracy of intra-abdominal fluid collection characterization in the era of multidetector computed tomography.

Journal Article Am Surg · February 2012 The purpose of this study was to test the hypothesis that with improved technology, the presence of abscess in a postoperative fluid collection may be prospectively made. This is an Institutional Review Board-approved, Health Insurance Portability and Acco ... Link to item Cite

Cancer in pregnancy: cross-sectional oncologic imaging utilization at a tertiary care center with an algorithmic approach to imaging.

Journal Article Clin Imaging · 2012 PURPOSE: To review utilization of imaging in pregnant patients with malignancies and define an imaging algorithm in this patient population. METHODS: Pregnant patients with concurrent diagnoses of malignancy from January 2002 to January 2011 were identifie ... Full text Link to item Cite

Radiation dose for routine clinical adult brain CT: Variability on different scanners at one institution.

Journal Article AJR Am J Roentgenol · August 2010 OBJECTIVE: The purpose of this study was to determine, using an anthropomorphic phantom, whether patients are subject to variable radiation doses based on scanner assignment for routine CT of the brain. MATERIALS AND METHODS: Twenty metal oxide semiconduct ... Full text Link to item Cite

Detection of pancreatic tumors, image quality, and radiation dose during the pancreatic parenchymal phase: effect of a low-tube-voltage, high-tube-current CT technique--preliminary results.

Journal Article Radiology · August 2010 PURPOSE: To intraindividually compare a low-tube-voltage (80 kVp), high-tube-current (675 mA) computed tomographic (CT) technique with a high-tube-voltage (140 kVp) CT protocol for the detection of pancreatic tumors, image quality, and radiation dose durin ... Full text Link to item Cite

Quantitative imaging in oncology patients: Part 2, oncologists' opinions and expectations at major U.S. cancer centers.

Journal Article AJR Am J Roentgenol · July 2010 OBJECTIVE: The purpose of this article is to examine oncologists' opinions and expectations concerning imaging and tumor measurements in patients with cancer. MATERIALS AND METHODS: An electronic mail survey was sent to 2,400 medical, gynecologic, and radi ... Full text Link to item Cite

Quantitative imaging in oncology patients: Part 1, radiology practice patterns at major U.S. cancer centers.

Journal Article AJR Am J Roentgenol · July 2010 OBJECTIVE: The objective of our study was to examine radiologists' opinions and practice patterns concerning tumor measurements in cancer patients. MATERIALS AND METHODS: An electronic mail survey was sent to 565 abdominal imaging radiologists at 55 U.S. N ... Full text Open Access Link to item Cite

MRI of the pelvis in women: 3D versus 2D T2-weighted technique.

Journal Article AJR Am J Roentgenol · July 2010 OBJECTIVE: The purpose of this study was to compare triplanar 2D T2-weighted turbo spin-echo MR images with reformatted images from a 3D T2-weighted turbo spin-echo sequence in analogous planes with respect to acquisition time, image quality, artifacts, an ... Full text Link to item Cite

Early first trimester fetal dose estimation method in a multivendor study of 16- and 64-MDCT scanners and low-dose imaging protocols.

Journal Article AJR Am J Roentgenol · October 2009 Featured Publication OBJECTIVE: The purpose of this study was to corroborate the relation between the estimated absorbed fetal dose derived from directly measured uterine doses early in the first trimester and the volume CT dose index (CTDI(vol)) for 16- and 64-MDCT of the mat ... Full text Link to item Cite

Radiation dose for body CT protocols: variability of scanners at one institution.

Journal Article AJR Am J Roentgenol · October 2009 Featured Publication OBJECTIVE: The objective of our study was to determine, using an anthropomorphic phantom, whether patients are subject to variable radiation doses based on scanner assignment for common body CT studies. MATERIALS AND METHODS: Twenty metal oxide semiconduct ... Full text Link to item Cite

Reply

Journal Article American Journal of Roentgenology · March 1, 2009 Full text Cite

A phase I-II study of docetaxel and atrasentan in men with castration-resistant metastatic prostate cancer.

Journal Article Clin Cancer Res · October 1, 2008 Featured Publication PURPOSE: The primary aims of this phase I-II study were to determine the maximum tolerated dose, dose-limiting toxicity, pharmacokinetics, and preliminary efficacy of the combination of docetaxel and the endothelin A receptor antagonist atrasentan as first ... Full text Link to item Cite

Early first-trimester fetal radiation dose estimation in 16-MDCT without and with automated tube current modulation.

Journal Article AJR Am J Roentgenol · April 2008 Featured Publication OBJECTIVE: The objective of our study was to correlate the estimated fetal absorbed radiation dose derived by directly measured uterine doses in the early first trimester and the volume CT dose index (CTDI(vol)) for 16-MDCT of the maternal chest, abdomen, ... Full text Link to item Cite

Radiation doses from small-bowel follow-through and abdomen/pelvis MDCT in pediatric Crohn disease.

Journal Article Pediatr Radiol · March 2008 Featured Publication BACKGROUND: The onset of Crohn disease (CD) can occur in childhood. Imaging, which often involves radiation, is frequent in CD both for disease diagnosis and follow-up. However, information regarding radiation dose for contemporary CT and fluoroscopy is no ... Full text Link to item Cite

Hypervascular liver tumors: low tube voltage, high tube current multi-detector row CT for enhanced detection--phantom study.

Journal Article Radiology · January 2008 Featured Publication PURPOSE: To prospectively evaluate, for the depiction of simulated hypervascular liver lesions in a phantom, the effect of a low tube voltage, high tube current computed tomographic (CT) technique on image noise, contrast-to-noise ratio (CNR), lesion consp ... Full text Link to item Cite

Practice patterns in imaging of the pregnant patient with abdominal pain: a survey of academic centers.

Journal Article AJR Am J Roentgenol · November 2007 OBJECTIVE: The purpose of our study was to evaluate current practice patterns in the imaging of pregnant women with abdominal complaints. MATERIALS AND METHODS: A survey was sent to the abdominal imaging division of 183 radiology residency programs in the ... Full text Link to item Cite

Radiation doses from small-bowel follow-through and abdominopelvic MDCT in Crohn's disease.

Journal Article AJR Am J Roentgenol · November 2007 OBJECTIVE: The purpose of our study was to compare organ and effective doses for small-bowel follow-through (SBFT) and abdominopelvic MDCT in adults with Crohn's disease, to retrospectively evaluate the number of radiographic examinations performed for Cro ... Full text Link to item Cite

Levator ani abnormality 6 weeks after delivery persists at 6 months.

Journal Article Am J Obstet Gynecol · July 2007 OBJECTIVE: Assess postpartum changes in the levator ani muscle using magnetic resonance imaging and relate these changes to obstetric events and risk factors associated with pelvic floor dysfunction. STUDY DESIGN: A board-certified radiologist specializing ... Full text Link to item Cite

Multi-detector row CT of the small bowel: peak enhancement temporal window--initial experience.

Journal Article Radiology · May 2007 PURPOSE: To prospectively determine quantitatively and qualitatively the timing of maximal enhancement of the normal small-bowel wall by using contrast material-enhanced multi-detector row computed tomography (CT). MATERIALS AND METHODS: This HIPAA-complia ... Full text Link to item Cite

Accuracy of abdominal radiography in acute small-bowel obstruction: does reviewer experience matter?

Journal Article AJR Am J Roentgenol · March 2007 OBJECTIVE: The purposes of this study were to determine the accuracy of abdominal radiography in the detection of acute small-bowel obstruction (SBO), to assess the role of reviewer experience, and to evaluate individual radiographic signs of SBO. MATERIAL ... Full text Link to item Cite

Abdominal pain: coronal reformations from isotropic voxels with 16-section CT--reader lesion detection and interpretation time.

Journal Article Radiology · January 2007 PURPOSE: To retrospectively assess if reader detection of intraabdominal pathologic findings on coronal reformations from isotropic voxels at 16-section computed tomography (CT) was similar to reader detection on transverse scans. MATERIALS AND METHODS: Th ... Full text Link to item Cite

3.0- Versus 1.5-T MR cholangiography: a pilot study.

Journal Article AJR Am J Roentgenol · February 2006 OBJECTIVE: The purpose of our study was to evaluate quantitative and qualitative image quality of MR cholangiography at a field strength of 3.0 T compared with the standard field strength of 1.5 T. MATERIALS AND METHODS: A standardized MR cholangiography s ... Full text Link to item Cite

Endoscopic ultrasound and computer tomography are inaccurate methods of classifying cystic pancreatic lesions.

Journal Article Dig Liver Dis · January 2006 BACKGROUND: Despite advances in imaging modalities, preoperative diagnosis of pancreatic cystic lesions remains difficult. AIM: To assess the accuracy of endoscopic ultrasound and computer tomography to preoperatively distinguish benign from potentially ma ... Full text Link to item Cite

Small-bowel obstruction: coronal reformations from isotropic voxels at 16-section multi-detector row CT.

Journal Article Radiology · January 2006 PURPOSE: To retrospectively assess the added value of coronal reformations of the abdomen and pelvis from isotropic voxels by using 16-section multi-detector row computed tomography (CT) for the diagnosis of small-bowel obstruction (SBO). MATERIALS AND MET ... Full text Link to item Cite

Optimization of multiplanar reformations from isotropic data sets acquired with 16-detector row helical CT scanner.

Journal Article Radiology · January 2006 Institutional review board approval and waiver of consent were obtained for the patient component of this retrospective HIPAA-compliant study. By using an anthropomorphic phantom and metal oxide semiconductor field effect transistor detectors, radiation do ... Full text Link to item Cite

Reply [8]

Journal Article American Journal of Roentgenology · December 1, 2005 Full text Cite

Acute appendicitis: added diagnostic value of coronal reformations from isotropic voxels at multi-detector row CT.

Journal Article Radiology · June 2005 PURPOSE: To assess retrospectively the added value of coronal reformations from isotropic voxels obtained with 16-section multi-detector row computed tomography (CT) of the abdomen and pelvis in patients with suspected acute appendicitis. MATERIALS AND MET ... Full text Link to item Cite

MDCT of abdominal wall hernias: is there a role for valsalva's maneuver?

Journal Article AJR Am J Roentgenol · March 2005 OBJECTIVE: Our objective was to evaluate the role of Valsalva's maneuver during MDCT for the diagnosis and characterization of abdominal wall hernias. SUBJECTS AND METHODS: From September 2002 to May 2003, 100 consecutive patients (37 men and 63 women; mea ... Full text Link to item Cite

Practice patterns in percutaneous image-guided intraabdominal abscess drainage: survey of academic and private practice centers.

Journal Article Radiology · December 2004 PURPOSE: To evaluate current practice patterns of percutaneous image-guided abdominal and pelvic abscess drainage in academic and private practice centers. MATERIALS AND METHODS: The institutional review board did not require approval for this study. In a ... Full text Link to item Cite

Percutaneous biopsy of periarterial soft tissue cuffs in the diagnosis of pancreatic carcinoma.

Journal Article Abdom Imaging · 2004 Pancreatic cancer may present on computed tomography (CT) as an isolated cuff of tumor surrounding the superior mesenteric artery (SMA) or celiac trunk, without an identifiable pancreatic mass. We reviewed our experience with imaging-guided biopsy of the s ... Full text Link to item Cite

MDCT of abdominal wall hernias: Is there a role for Valsalva maneuver?

Conference AMERICAN JOURNAL OF ROENTGENOLOGY · January 1, 2004 Link to item Cite