Service to the Profession
To review research grant applications and recommend recipients to the AST Research Network committee.
The goals of NUGIFT INC are to transplant genetically modified pig organs into primates and then humans with minimal or no immunosuppression, raise pigs in very large numbers and develop a way to harvest and store pig organs for a considerable period of time.
About the Conference
The Duke Transplant Center (DTC) will host the XXI Great Lakes Transplant Immunology Forum November 2-3, 2020.
The Great Lakes Transplantation Immunology Forum (GLTIF) is an annual meeting that was inaugurated in Ann Arbor, Michigan in 2000 to provide a regional forum to share ongoing research findings, get feedback on new research ideas, promote networking, and generate research collaborations.
Dr. Charles G. Orosz (1949-2005) proposed the establishment of an annual regional transplant immunology meeting which would facilitate interactions and the free exchange of ideas and technologies between labs. This idea evolved into the annual Erie (now Great Lakes) Transplant Forum, which will hold its 21st meeting this fall, 2020.*
*captured and modified from Memoriam of Dr. Orozs in American Journal of Transplantation 2005; 5: 2805–2806.
About This Topic
The idea of immunological tolerance was developed from seminal works by Ray Owen, Sir F. MacFarlane Burnet, and Sir Peter Medawar in the mid-20th century. These findings drove transplantation research to identify mechanisms of immune tolerance. However, despite partial success, it was unable to stably induce tolerance in immunocompetent recipients. In the special issue, “Multiple Aspects of Transplant Tolerance”, we will provide a forum for presenting mechanisms, strategies, and challenges for promoting tolerance in transplantation. This will include description of cell populations plays a crucial role in tolerance as well as cell-based approaches (Treg, Mreg, DCreg, CD8 Treg, Tr1, and not excluding BM, apoptotic cell-based strategies), identification/validation of clinical tolerance strategy and biomarkers. Finally, we will also cover B cell immunobiology in transplantation and strategies for B cell and plasma cell tolerance. The special issue will also be open to any author, but mainly invited by guest editor. Each submission will be reviewed by at least two reviewers to ensure a very high quality of papers selected for the Special Issue.