Selected Grants
Duke Research Training Program in Surgical Oncology
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2024 - 2029The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program
ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028Harnessing treatment-induced tumor evolution and collateral sensitivities using a human rectal cancer co-clinical platform
ResearchMentor · Awarded by National Cancer Institute · 2022 - 2027Medical Scientist Training Program
Inst. Training Prgm or CMEPreceptor · Awarded by National Institute of General Medical Sciences · 2022 - 2027University Training Program in Biomolecular and Tissue Engineering
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027Pharmacological activation of a newly discovered KEAP1-ATF4-CHOP axis to select against targeted therapy resistance in NSCLC
ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2027Chromosomal Instability and 17p Loss Sensitize Cancer Cells to NDE1 Depletion
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2027Building Interdisciplinary Research Careers in Women's Health - BIRCWH
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2002 - 2027Mechanisms of Macrophage-Mediated Immune Evasion in Residual Tumors
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2027Otolaryngology Surgeon- Scientist career Path (OSSP) program
Inst. Training Prgm or CMEMentor · Awarded by National Institute on Deafness and Other Communication Disorders · 2022 - 2027Wnt signaling in obesity-associated colorectal cancer
ResearchCo Investigator · Awarded by National Cancer Institute · 2022 - 2027Mechanism-based targeting of unique survival signaling in residual tumors
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027Lineage-specific signaling and targeting of PI3K gamma in myeloid malignancies
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027Duke ACS Institutional Research Grant
ResearchSignificant Contributor · Awarded by American Cancer Society, Inc. · 2024 - 2026Cell and Molecular Biology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026Duke Center for Advancement of Child Health (CAtCH).
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026Tripping the core regulatory circuitry: Evaluating the tumor-intrinsic and extrinsic effects of Triptolide in CIC-DUX4 sarcoma (CDS)
ResearchMentor · Awarded by American Society of Clinical Oncology · 2024 - 2025Dissecting the evolutionary landscape of treatment resistance in rectal cancer using patient-derived models.
ResearchMentor · Awarded by American Gastroenterological Association · 2022 - 2025Pharmacological Sciences Training Grant
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025Genetic and Genomics Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2020 - 2025Investigating the Impact of ABL Kinase Signaling on Epigenetic Reprogramming in Metastatic Triple Negative Breast Cancer
FellowshipCollaborator · Awarded by National Institutes of Health · 2022 - 2025NGF recruits nerve fibers to reprogram an immunosuppressive microenvironment in melanoma
ResearchCollaborator · Awarded by National Institutes of Health · 2020 - 2025Synthetic lethality by targeting the core senescent mechanism in lung cancer.
ResearchCollaborator · Awarded by National Institutes of Health · 2020 - 2025Institutional Summer Undergraduate Research Fellowship (SURF)
Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2018 - 2025ABL-regulated transcriptional and epigenetic networks promote outgrowth of breast cancer metastases revealing novel therapeutic targets
ResearchCollaborator · Awarded by Department of Defense · 2022 - 2024The mechanical role of the glycocalyx in cancer cell adhesion
ResearchCo-Mentor · Awarded by National Institutes of Health · 2020 - 2024Exploitation of XLF signaling and the DNA Damage Response as a novel therapeutic strategy in cholangiocarcinoma
ResearchMentor · Awarded by American College of Surgeons · 2021 - 2024Evaluation of voltage-gated calcium ion channels as a therapeutic target in intrahepatic cholangiocarcinoma
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2024Improving Therapeutic Efficacy and Durability in FGFR2 Fusion Positive Cholangiocarcinoma
ResearchMentor · Awarded by The Cholangiocarcinoma Foundation · 2022 - 2024HOXB13 as a therapeutic target in prostate cancer
ResearchCo Investigator · Awarded by Prostate Cancer Foundation · 2020 - 2024Exploiting targeted therapy-induced ATM dependence in residual lung tumors
ResearchPrincipal Investigator · Awarded by Department of Defense · 2021 - 2023Defining the Mechanistic Determinants of Response to Selective Electron Transport Chain Inhibition in Cancer
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2023Identification and Characterization of Novel Cis-Regulatory Elements Controlling PTEN Expression
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2022Uncovering actionable signaling pathways required for solid tumor brain metastasis
ResearchMentor · Awarded by National Institutes of Health · 2019 - 2022Targeting tumor-specific apoptosis regulation in advanced ER+ breast cancer
ResearchPrincipal Investigator · Awarded by Department of Defense · 2019 - 2022Selectively targeting apoptosis in PIK3CA mutant colorectal cancers
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2022Medical Scientist Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1997 - 2022Computational Structure-Based Protein Design Non-competing Renewal (Yr. 12)
ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2008 - 2022Determining the Sub-Cellular Organelles that Link Lipid Signaling and Epigenetics
ResearchSignificant Contributor · Awarded by National Institutes of Health · 2019 - 2021Bioinformatics and Computational Biology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2021Mechanisms of immune checkpoint resistance mediated by LKB1 tumor suppressor in lung cancer
ResearchMentor · Awarded by Department of Defense · 2019 - 2021Strategies to overcome immunotherapy resistance in LKB1 and KEAP/NRF2 mutated NSCLC: modulating ferroptosis to restore immune sensitivity
FellowshipPrincipal Investigator · Awarded by Society for Immunotherapy of Cancer · 2020 - 2021Decoding human genetic variation by functional dissection of beta2-adrenergic receptor signaling
ResearchCollaborating Investigator · Awarded by American Heart Association · 2019 - 2021Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2021Precision targeting of altered mitochondrial states in ovarian cancer
ResearchPrincipal Investigator · Awarded by Ovarian Cancer Research Fund, Inc. · 2015 - 2021Identification and validation of the PAX3-FOXO1 protein interactome
ResearchCollaborator · Awarded by St. Baldrick's Foundation · 2018 - 2020Targeting the Hippo pathway in Ras-driven rhabdomyosarcoma
ResearchCollaborator · Awarded by V Foundation for Cancer Research · 2016 - 2020High-throughput screening of arrayed single cells for automated analysis of phenotypic heterogeneity
ResearchCo Investigator · Awarded by Celldom · 2018 - 2020Genetics Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1979 - 2020Organization and Function of Cellular Structure
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020Pharmacological Sciences Training Program
Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020Evaluating small molecules that potentiate anti-tumor immunity
ResearchPrincipal Investigator · Awarded by Tavros Therapeutics · 2020 - 2020Topological Methods for Morphology: Classifying Shape and Function via Dictionary Learning
ResearchCo-Principal Investigator · Awarded by Columbia University · 2016 - 2020Single cell functional dissection of tumor microenviornment-driven drug resistance
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2020Pharmacology Industry Internships for Ph.D. Students
Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2017 - 2019Targeting differential apoptosis regulation in triple negative breast cancer
ResearchPrincipal Investigator · Awarded by Department of Defense · 2016 - 2019Identification of synthetic lethal interactors in pancreatic cancer
ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2015 - 2019Exploring BCL-XL addiction in pancreatic ductal adenocarcinoma
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2019RalA signal transduction
ResearchCollaborator · Awarded by National Institutes of Health · 2002 - 2019Copy Number Alterations in Low Mutation Cancer
ResearchCo-Mentor · Awarded by National Institutes of Health · 2018 - 2019Exploiting collateral sensitivity to target kinase inhibitor-resistant lung cancers
ResearchPrincipal Investigator · Awarded by Burroughs Wellcome Fund · 2017 - 2018Unmasking targetable dependencies in cancer with intrinsic or acquired resistance to anti-cancer therapies
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2018Integration of signaling and metabolic pathways in the regulation of EMT
ResearchPrincipal Investigator · Awarded by US-Israel Binational Science Foundation · 2016 - 2018Profiling Gene Interactions in the Human Kinome
FellowshipPrincipal Investigator · Awarded by National Science Foundation · 2015 - 2018Targeting undruggable oncogenes through the epigenome
ResearchPrincipal Investigator · Awarded by Element Genomics, Inc. · 2017 - 2018Designing durable apoptosis-targeting therapies for acute myeloid leukemia
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018Mapping the landscape of drug sensitizers in human cancers
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2017Genomic and Computational Approaches for Development of Novel Anticancer Therapies
FellowshipPrincipal Investigator · Awarded by Schlumberger Foundation · 2015 - 2017Systematic design of CDK4/6 inhibitor-based combination therapies
ResearchPrincipal Investigator · Awarded by G1 Therapeutics Inc. · 2015 - 2016A Platform for Real-time Drug Profiling of Patient-Derived Melanomas
FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2014 - 2016Cancer Biology Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Cancer Institute · 1993 - 2016Systematic dissection of the breast cancer microenvironment using the MicroSCALE Toolkit
ResearchPrincipal Investigator · Awarded by V Foundation for Cancer Research · 2013 - 2015External Relationships
- Celldom, Inc.
- Decrypt Bio
- Guidepoint Global
- Retroviral Therapeutics
- Simple Therapeutics
- Stelexis Therapeutics
- Tavros Therapeutics
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.