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Kris Cameron Wood

Associate Professor of Pharmacology and Cancer Biology
Pharmacology & Cancer Biology

Selected Grants


The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program

ResearchPreceptor · Awarded by National Institutes of Health · 2023 - 2028

Medical Scientist Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2022 - 2027

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

Pharmacological activation of a newly discovered KEAP1-ATF4-CHOP axis to select against targeted therapy resistance in NSCLC

ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2027

The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program

ResearchPreceptor · Awarded by National Institutes of Health · 2023 - 2028

Medical Scientist Training Program

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2022 - 2027

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

Pharmacological activation of a newly discovered KEAP1-ATF4-CHOP axis to select against targeted therapy resistance in NSCLC

ResearchPrincipal Investigator · Awarded by Department of Defense · 2024 - 2027

Chromosomal Instability and 17p Loss Sensitize Cancer Cells to NDE1 Depletion

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2027

Mechanisms of Macrophage-Mediated Immune Evasion in Residual Tumors

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2027

Otolaryngology Surgeon- Scientist career Path (OSSP) program

Inst. Training Prgm or CMEMentor · Awarded by National Institute on Deafness and Other Communication Disorders · 2022 - 2027

Wnt signaling in obesity-associated colorectal cancer

ResearchCo Investigator · Awarded by National Cancer Institute · 2022 - 2027

Mechanism-based targeting of unique survival signaling in residual tumors

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027

Lineage-specific signaling and targeting of PI3K gamma in myeloid malignancies

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027

Duke ACS Institutional Research Grant

ResearchSignificant Contributor · Awarded by American Cancer Society, Inc. · 2024 - 2026

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Duke Center for Advancement of Child Health (CAtCH).

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Dissecting the evolutionary landscape of treatment resistance in rectal cancer using patient-derived models.

ResearchMentor · Awarded by American Gastroenterological Association · 2022 - 2025

Pharmacological Sciences Training Grant

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Genetic and Genomics Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2020 - 2025

Investigating the Impact of ABL Kinase Signaling on Epigenetic Reprogramming in Metastatic Triple Negative Breast Cancer

FellowshipCollaborator · Awarded by National Institutes of Health · 2022 - 2025

NGF recruits nerve fibers to reprogram an immunosuppressive microenvironment in melanoma

ResearchCollaborator · Awarded by National Institutes of Health · 2020 - 2025

Synthetic lethality by targeting the core senescent mechanism in lung cancer.

ResearchCollaborator · Awarded by National Institutes of Health · 2020 - 2025

Institutional Summer Undergraduate Research Fellowship (SURF)

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2018 - 2025

The mechanical role of the glycocalyx in cancer cell adhesion

ResearchCo-Mentor · Awarded by National Institutes of Health · 2020 - 2024

Exploitation of XLF signaling and the DNA Damage Response as a novel therapeutic strategy in cholangiocarcinoma

ResearchMentor · Awarded by American College of Surgeons · 2021 - 2024

Evaluation of voltage-gated calcium ion channels as a therapeutic target in intrahepatic cholangiocarcinoma

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2024

Uncovering actionable signaling pathways required for solid tumor brain metastasis

ResearchMentor · Awarded by National Institutes of Health · 2019 - 2024

Exploiting targeted therapy-induced ATM dependence in residual lung tumors

ResearchPrincipal Investigator · Awarded by Department of Defense · 2021 - 2023

Improving Therapeutic Efficacy and Durability in FGFR2 Fusion Positive Cholangiocarcinoma

ResearchMentor · Awarded by The Cholangiocarcinoma Foundation · 2022 - 2023

HOXB13 as a therapeutic target in prostate cancer

ResearchCo Investigator · Awarded by Prostate Cancer Foundation · 2020 - 2023

Defining the Mechanistic Determinants of Response to Selective Electron Transport Chain Inhibition in Cancer

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2023

Identification and Characterization of Novel Cis-Regulatory Elements Controlling PTEN Expression

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2022

Targeting tumor-specific apoptosis regulation in advanced ER+ breast cancer

ResearchPrincipal Investigator · Awarded by Department of Defense · 2019 - 2022

Selectively targeting apoptosis in PIK3CA mutant colorectal cancers

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2022

Medical Scientist Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1997 - 2022

Computational Structure-Based Protein Design Non-competing Renewal (Yr. 12)

ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2008 - 2022

Determining the Sub-Cellular Organelles that Link Lipid Signaling and Epigenetics

ResearchSignificant Contributor · Awarded by National Institutes of Health · 2019 - 2021

Bioinformatics and Computational Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2021

Mechanisms of immune checkpoint resistance mediated by LKB1 tumor suppressor in lung cancer

ResearchMentor · Awarded by Department of Defense · 2019 - 2021

Strategies to overcome immunotherapy resistance in LKB1 and KEAP/NRF2 mutated NSCLC: modulating ferroptosis to restore immune sensitivity

FellowshipPrincipal Investigator · Awarded by Society for Immunotherapy of Cancer · 2020 - 2021

Decoding human genetic variation by functional dissection of beta2-adrenergic receptor signaling

ResearchCollaborating Investigator · Awarded by American Heart Association · 2019 - 2021

Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2021

Precision targeting of altered mitochondrial states in ovarian cancer

ResearchPrincipal Investigator · Awarded by Ovarian Cancer Research Fund, Inc. · 2015 - 2021

Identification and validation of the PAX3-FOXO1 protein interactome

ResearchCollaborator · Awarded by St. Baldrick's Foundation · 2018 - 2020

Targeting the Hippo pathway in Ras-driven rhabdomyosarcoma

ResearchCollaborator · Awarded by V Foundation for Cancer Research · 2016 - 2020

Genetics Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1979 - 2020

Pharmacological Sciences Training Program

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020

Organization and Function of Cellular Structure

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020

Evaluating small molecules that potentiate anti-tumor immunity

ResearchPrincipal Investigator · Awarded by Tavros Therapeutics · 2020 - 2020

Topological Methods for Morphology: Classifying Shape and Function via Dictionary Learning

ResearchCo-Principal Investigator · Awarded by Columbia University · 2016 - 2020

Single cell functional dissection of tumor microenviornment-driven drug resistance

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2020

Pharmacology Industry Internships for Ph.D. Students

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2017 - 2019

Targeting differential apoptosis regulation in triple negative breast cancer

ResearchPrincipal Investigator · Awarded by Department of Defense · 2016 - 2019

Identification of synthetic lethal interactors in pancreatic cancer

ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2015 - 2019

Exploring BCL-XL addiction in pancreatic ductal adenocarcinoma

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2019

RalA signal transduction

ResearchCollaborator · Awarded by National Institutes of Health · 2002 - 2019

Copy Number Alterations in Low Mutation Cancer

ResearchCo-Mentor · Awarded by National Institutes of Health · 2018 - 2019

Exploiting collateral sensitivity to target kinase inhibitor-resistant lung cancers

ResearchPrincipal Investigator · Awarded by Burroughs Wellcome Fund · 2017 - 2018

Unmasking targetable dependencies in cancer with intrinsic or acquired resistance to anti-cancer therapies

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2018

Integration of signaling and metabolic pathways in the regulation of EMT

ResearchPrincipal Investigator · Awarded by US-Israel Binational Science Foundation · 2016 - 2018

Profiling Gene Interactions in the Human Kinome

FellowshipPrincipal Investigator · Awarded by National Science Foundation · 2015 - 2018

Targeting undruggable oncogenes through the epigenome

ResearchPrincipal Investigator · Awarded by Element Genomics, Inc. · 2017 - 2018

Designing durable apoptosis-targeting therapies for acute myeloid leukemia

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018

Mapping the landscape of drug sensitizers in human cancers

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2017

Genomic and Computational Approaches for Development of Novel Anticancer Therapies

FellowshipPrincipal Investigator · Awarded by Schlumberger Foundation · 2015 - 2017

Systematic design of CDK4/6 inhibitor-based combination therapies

ResearchPrincipal Investigator · Awarded by G1 Therapeutics Inc. · 2015 - 2016

A Platform for Real-time Drug Profiling of Patient-Derived Melanomas

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2014 - 2016

Cancer Biology Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Cancer Institute · 1993 - 2016

Systematic dissection of the breast cancer microenvironment using the MicroSCALE Toolkit

ResearchPrincipal Investigator · Awarded by V Foundation for Cancer Research · 2013 - 2015

External Relationships


  • Celldom, Inc.
  • Decrypt Bio
  • Guidepoint Global
  • Simple Therapeutics
  • Tavros Therapeutics

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.