Scholars@Duke
Krista Lynn Haines

Krista Lynn Haines

Assistant Professor of Surgery
Trauma, Acute, and Critical Care Surgery

Selected Publications

Enteral and Parenteral Nutrition Timing in eICU Collaborative Research Database by Race: A Retrospective Observational Study.

Journal Article J Surg Res · November 16, 2024 INTRODUCTION: Racial and ethnic disparities in malnutrition are well-known, but it is unknown if there are disparities in early nutrition delivery for intensive care unit (ICU) patients, which is associated with better outcomes. We investigated the timing ... Full text Link to item Cite

A Multifactorial Analysis of Trauma Outcomes: Comorbidities, Race, and Socioeconomic Status.

Journal Article J Surg Res · November 7, 2024 INTRODUCTION: Trauma patients with comorbid conditions are known to have poorer outcomes. We hypothesize that these outcomes are further influenced by race or ethnicity and socioeconomic status. METHODS: We queried patient records in the Trauma Quality Imp ... Full text Link to item Cite

Association of Area Deprivation Index With Mortality in Critically Ill Adults With COVID-19.

Journal Article Am J Crit Care · November 1, 2024 BACKGROUND: Various social determinants of health have been established as significant risk factors for COVID-19 transmission, prevalence, incidence, and mortality. Area deprivation index (ADI, a composite score made up of educational, housing, and poverty ... Full text Link to item Cite

Performance of Artificial Intelligence Content Detectors Using Human and Artificial Intelligence-Generated Scientific Writing.

Journal Article Ann Surg Oncol · October 2024 BACKGROUND: Few studies have examined the performance of artificial intelligence (AI) content detection in scientific writing. This study evaluates the performance of publicly available AI content detectors when applied to both human-written and AI-generat ... Full text Link to item Cite

Age-Neutral Surgical Stabilization of Rib Fractures: Breaking the Ageism Barrier.

Journal Article J Surg Res · October 2024 INTRODUCTION: Surgical stabilization of rib fractures (SSRF) is associated with lower rates of mortality and fewer complications. This study evaluates whether the decision to undergo SSRF is associated with age, race, ethnicity, and insurance status and as ... Full text Link to item Cite

Predictive Energy Equations Inaccurately Estimate Metabolic Demands of Older Adult Trauma Patients.

Journal Article J Surg Res · October 2024 INTRODUCTION: Suboptimal nutrition promotes unfavorable outcomes in trauma patients, particularly among those aged 60 and over. While many institutions employ predictive energy equations to determine patients' energy requirements, mounting evidence shows t ... Full text Link to item Cite

The Earlier the Better: Surgical Stabilization of Rib Fractures Associated With Improved Outcomes.

Journal Article J Surg Res · October 2024 INTRODUCTION: Surgical stabilization of rib fractures (SSRF) has been associated with lower rates of mortality and fewer respiratory complications. This study sought to evaluate the association between SSRF timing and patient outcomes. METHODS: This retros ... Full text Link to item Cite

Whole blood resuscitation for injured patients requiring transfusion: A systematic review, meta-analysis, and practice management guideline from the Eastern Association for the Surgery of Trauma.

Journal Article J Trauma Acute Care Surg · September 1, 2024 INTRODUCTION: Whole blood (WB) resuscitation has reemerged as a resuscitation strategy for injured patients. However, the effect of WB-based resuscitation on outcomes has not been established. The primary objective of this guideline was to develop evidence ... Full text Link to item Cite

Firearm Ownership: A Key Factor to Consider in Firearm Suicide Deaths in Children, Despite State Gun Laws.

Journal Article J Surg Res · September 2024 INTRODUCTION: Firearm-related suicides among children present a significant public health concern and a tragic loss of young lives. This study explores the relationship between firearm-related suicides, gun ownership, and state-specific gun laws. METHODS: ... Full text Link to item Cite

Disparities and Differential Allocation of Nutritional Therapies

Journal Article Current Surgery Reports · September 1, 2024 Purpose of Review: Disparities in malnutrition often exist prior to hospitalization or illness. These disparities may compound unjust negative health outcomes. This review discusses disparities seen in those diagnosed with malnutrition as well as describes ... Full text Cite

Can We Actually Predict Long-Term Patient Satisfaction After Traumatic Brain Injury?

Journal Article J Surg Res · September 2024 INTRODUCTION: The Traumatic Brain Injury - Patient Reported Outcome (TBI-PRO) model was previously derived to predict long-term patient satisfaction as assessed by the Quality of Life After Brain Injury (QOLIBRI) score. The aim of this study is to external ... Full text Link to item Cite

The Ethical Obligation to Treat Infectious Patients: A Systematic Review of Reasons.

Journal Article Clin Infect Dis · August 16, 2024 During pandemics, healthcare providers struggle with balancing obligations to self, family, and patients. While HIV/AIDS seemed to settle this issue, coronavirus disease 2019 (COVID-19) rekindled debates regarding treatment refusal. We searched MEDLINE, Em ... Full text Link to item Cite

Child Firearm-Related Homicide and Suicide by State Legislation in the US (2009-2020).

Journal Article J Am Coll Surg · July 11, 2024 BACKGROUND: Firearms are the leading cause of death among U.S. children and adolescents. This study evaluates whether state gun laws are associated with firearm suicides and homicides in children. STUDY DESIGN: This is a cross-sectional database study comp ... Full text Link to item Cite

The impact of hypertonic saline on damage control laparotomy after penetrating abdominal trauma.

Journal Article Eur J Trauma Emerg Surg · June 2024 PURPOSE: The inability to achieve primary fascial closure (PFC) after emergency laparotomy increases the rates of adverse outcomes including fistula formation, incisional hernia, and intraabdominal infection. Hypertonic saline (HTS) infusion improves early ... Full text Link to item Cite

Outcomes by time-to-OR for penetrating abdominal trauma patients.

Journal Article Am J Emerg Med · May 2024 INTRODUCTION: Time-To-OR is a critical process measure for trauma performance. However, this measure has not consistently demonstrated improvement in outcome. STUDY DESIGN: Using TQIP, we identified facilities by 75th percentile time-to-OR to categorize sl ... Full text Link to item Cite

Systematic Literature Review of Health-Related Quality-of-Life Measures for Caregivers of Older Adult Trauma Patients.

Journal Article J Surg Res · May 2024 INTRODUCTION: As the older adult population increases, hospitals treat more older adults with injuries. After leaving, these patients suffer from decreased mobility and independence, relying on care from others. Family members often assume this responsibil ... Full text Link to item Cite

Racial and ethnic demographics in malnutrition related deaths.

Journal Article Clin Nutr ESPEN · April 2024 BACKGROUND AND AIMS: Currently, 40 million Americans are food insecure. They are forced to skip meals and buy non-nutritious food, leading to health disparities for those of low socioeconomic status. This study aims to investigate relationships between mal ... Full text Link to item Cite

Unspoken Truths: Mental Health Among Academic Surgeons.

Journal Article Ann Surg · March 1, 2024 OBJECTIVE: To characterize the current state of mental health within the surgical workforce in the United States. BACKGROUND: Mental illness and suicide is a growing concern in the medical community; however, the current state is largely unknown. METHODS: ... Full text Link to item Cite

Factors Associated with Discharge to Skilled Nursing Facility Following Gunshot Wounds.

Journal Article J Surg Res · February 2024 INTRODUCTION: Firearm injury is a public health crisis. Most victims are minorities in underserved neighborhoods. Measuring firearm injury by mortality underestimates its impact, as most victims survive to discharge. This study was done to determine if rac ... Full text Link to item Cite

Mobile Application-Based Communication Facilitation Platform for Family Members of Critically Ill Patients: A Randomized Clinical Trial.

Journal Article JAMA Netw Open · January 2, 2024 IMPORTANCE: Unmet and racially disparate palliative care needs are common in intensive care unit (ICU) settings. OBJECTIVE: To test the effect of a primary palliative care intervention vs usual care control both overall and by family member race. DESIGN, S ... Full text Link to item Cite

The Use of Parenteral Nutrition and Disparities in Its Allocation Following Traumatic Injury.

Journal Article J Surg Res · January 2024 INTRODUCTION: Severe traumatic injury requires rapid and extensive deployment of resources to save the lives of the critically injured. The sequelae of traumatic injuries frequently require extensive intervention obligating patients to a complicated recove ... Full text Link to item Cite

Where Are the Children? A Thematic Analysis of State, Territory, and Tribal Organization Comprehensive Cancer Control Plans.

Journal Article J Pediatr Surg · January 2024 BACKGROUND: The Center for Disease Control's Comprehensive Cancer Control Program (CCCP) funds initiatives in fifty states, the District of Columbia, seven U.S. territories, and seven tribal organizations to prevent and control cancer. These initiatives in ... Full text Link to item Cite

The impact of hypertonic saline on damage control laparotomy after penetrating abdominal trauma

Journal Article EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY · 2024 Full text Cite

Amino acid kinetics in the critically ill.

Journal Article Curr Opin Clin Nutr Metab Care · January 1, 2024 PURPOSE OF REVIEW: Stable isotope methods have been used for many years to assess whole body protein and amino acid kinetics in critically ill patients. In recent years, new isotope approaches and tracer insights have been developed. The tracer pulse appro ... Full text Link to item Cite

GUIDELINE ADHERENCE IMPROVES RIB FRACTURE PATIENT OUTCOMES

Conference CRITICAL CARE MEDICINE · 2024 Cite

A National Comparison of Volume and Acuity for Adult and Pediatric Trauma: A Trauma Quality Improvement Program Cohort Study.

Journal Article J Surg Res · November 2023 INTRODUCTION: Most injured children receive trauma care outside of a pediatric trauma center. Differences in physiology, dosing, and injury pattern limit extrapolation of adult trauma principles to pediatrics. We compare US trauma center experience with pe ... Full text Link to item Cite

Using Crowdfunding Campaigns to Examine Financial Toxicity and Logistical Burdens Facing Families of Children With Wilms Tumor.

Journal Article J Surg Res · November 2023 INTRODUCTION: Treatment for pediatric solid tumors is often intense and multidisciplinary and can create a substantial financial burden for families. Assessing these burdens, termed the financial toxicity of treatment, can be difficult. Using Wilms tumor a ... Full text Link to item Cite

Early enteral nutrition is associated with improved outcomes in critically ill mechanically ventilated medical and surgical patients.

Journal Article Clin Nutr ESPEN · October 2023 BACKGROUND AND AIMS: Data suggest that guidelines for enteral nutrition (EN) initiation are not closely followed in clinical practice. In addition, critically ill mechanically ventilated (MV) patients have varying metabolic needs, which often increase and ... Full text Link to item Cite

Going beyond the means: Exploring the role of bias from digital determinants of health in technologies.

Journal Article PLOS Digit Health · October 2023 BACKGROUND: In light of recent retrospective studies revealing evidence of disparities in access to medical technology and of bias in measurements, this narrative review assesses digital determinants of health (DDoH) in both technologies and medical formul ... Full text Link to item Cite

Change to Mixed-Lipid Emulsion From Soybean Oil-Based Lipid Emulsion in Pediatric Patients.

Journal Article JAMA Netw Open · September 5, 2023 IMPORTANCE: Critically ill pediatric patients often require parenteral nutrition (PN) in the intensive care unit (ICU). Literature suggests mixed lipid emulsions (LE) with soybean oil reduction strategies may improve outcomes. OBJECTIVE: To examine the ass ... Full text Open Access Link to item Cite

State Firearm Laws and Rate of Assault-Related Firearm Death.

Journal Article J Am Coll Surg · September 1, 2023 BACKGROUND: Studying firearm-related mortality is important to reduce preventable firearm death in the US. This study aims to determine the relationship between firearm laws and assault death with firearms. STUDY DESIGN: This ecologic study used public dat ... Full text Link to item Cite

Factors Associated With Triage Decisions in Older Adult Trauma Patients: Impact on Mortality and Morbidity.

Journal Article J Surg Res · August 2023 INTRODUCTION: As medical advances have significantly increased the life expectancy among older adults, the number of older patients requiring trauma care has risen proportionately. Nevertheless, it is unclear among this growing population which sociodemogr ... Full text Link to item Cite

Lipid emulsions in parenteral nutrition: does it matter?

Journal Article Curr Opin Crit Care · August 1, 2023 PURPOSE OF REVIEW: Recently, clinicians have shown interest in switching patients to nonsoybean-based intravenous lipid emulsion (ILE) formulas for parental nutrition (PN) due to adverse outcomes related to high Omega-6 content in soybean oil (SO) ILE's. T ... Full text Open Access Link to item Cite

Optimal Nutrition in the Older Adult: Beneficial Versus Ineffective Supplements.

Journal Article Curr Nutr Rep · June 2023 PURPOSE OF REVIEW: Proper nutrition in older adults is essential, as nutritional deficiencies are common in this population. This review aims to summarize the benefits and risks of nutritional supplementation in the older adult population including the eff ... Full text Link to item Cite

Risk of Surgical Intervention in Children with Diagnoses of Cancer and Preoperative Malnutrition: A National Analysis.

Journal Article J Pediatr Surg · June 2023 BACKGROUND: Perioperative nutrition is a critical component of appropriate healing and recovery after surgery. We sought to identify perioperative risk in children with cancer and low preoperative hypoalbuminemia undergoing surgical intervention. METHODS: ... Full text Link to item Cite

Non-surgical management and analgesia strategies for older adults with multiple rib fractures: A systematic review, meta-analysis, and joint practice management guideline from the Eastern Association for the Surgery of Trauma and the Chest Wall Injury Society.

Journal Article J Trauma Acute Care Surg · March 1, 2023 BACKGROUND: Chest wall injury in older adults is a significant cause of morbidity and mortality. Optimal nonsurgical management strategies for these patients have not been fully defined regarding level of care, incentive spirometry (IS), noninvasive positi ... Full text Link to item Cite

Management of adult renal trauma: a practice management guideline from the eastern association for the surgery of trauma.

Journal Article BMC Surg · January 27, 2023 BACKGROUND: The kidney is the most frequently injured component of the genitourinary system, accounting for 5% of all trauma cases. Several guidelines by different societies address the management of urological trauma. However, unanswered questions remain ... Full text Link to item Cite

Insurance Status and Ethnicity Impact Health Disparities in Rates of Advance Directives in Trauma.

Journal Article Am Surg · January 2023 INTRODUCTION: Advanced directives (ADs) provide a framework from which families may understand patient's wishes. However, end-of-life planning may not be prioritized by everyone. This analysis aimed to determine what populations have ADs and how they affec ... Full text Link to item Cite

Trajectories of Palliative Care Needs in the ICU and Long-Term Psychological Distress Symptoms.

Journal Article Crit Care Med · January 1, 2023 OBJECTIVES: While palliative care needs are assumed to improve during ICU care, few empiric data exist on need trajectories or their impact on long-term outcomes. We aimed to describe trajectories of palliative care needs during ICU care and to determine i ... Full text Link to item Cite

Restrictive Firearm Laws and Firearm-Related Suicide.

Journal Article J Am Coll Surg · January 1, 2023 BACKGROUND: There were 23,854 suicides by firearms in 2017 in the US, accounting for 60% of all gun deaths. Studying firearm-related mortalities is vital for reducing preventable gun deaths. This study aims to determine the association between state-level ... Full text Link to item Cite

Efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of acute pain after orthopedic trauma: a practice management guideline from the Eastern Association for the Surgery of Trauma and the Orthopedic Trauma Association.

Journal Article Trauma Surg Acute Care Open · 2023 OBJECTIVES: Fracture is a common injury after a traumatic event. The efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) to treat acute pain related to fractures is not well established. METHODS: Clinically relevant questions were determi ... Full text Link to item Cite

Screening and intervention for intimate partner violence at trauma centers and emergency departments: an evidence-based systematic review from the Eastern Association for the Surgery of Trauma.

Journal Article Trauma Surg Acute Care Open · 2023 BACKGROUND: Intimate partner violence (IPV) is a serious public health issue with a substantial burden on society. Screening and intervention practices vary widely and there are no standard guidelines. Our objective was to review research on current practi ... Full text Link to item Cite

Need for Assessment of Older Adult Caregivers; The Silent Secondary Trauma Patient

Conference JOURNAL OF THE AMERICAN GERIATRICS SOCIETY · 2023 Cite

Addressing Unmet Needs Among Family Members of Critically Ill Patients: The ICUconnect Randomized Clinical Trial

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2023 Cite

Exercise Attenuates Septic Inflammatory Response in Murine Model

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2023 Cite

Exercise Attenuates Septic Inflammatory Response in Murine Model

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2023 Cite

Experience With Trauma-Induced ARDS: A Retrospective Study of US Wartime Casualties 2003-2015.

Journal Article J Spec Oper Med · December 16, 2022 BACKGROUND: The purpose of our study was to assess risks/ outcomes of acute respiratory distress syndrome (ARDS) in US combat casualties. We hypothesized that combat trauma patients with ARDS would have worse outcomes based on mechanism of injury (MOI) and ... Full text Link to item Cite

Tracheostomy

Chapter · December 15, 2022 Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. ... Link to item Cite

Racial and Ethnic Differences in the Prevalence of Do-Not-Resuscitate Orders among Older Adults with Severe Traumatic Brain Injury.

Journal Article J Intensive Care Med · December 2022 BACKGROUND: Older adults suffering from traumatic brain injury (TBI) are subject to higher injury burden and mortality. Do Not Resuscitate (DNR) orders are used to provide care aligned with patient wishes, but they may not be equitably distributed across r ... Full text Open Access Link to item Cite

Racial Differences in Firearms Used and Autopsies Following Gun Deaths Exist.

Journal Article J Surg Res · November 2022 INTRODUCTION: Disparities in gun violence across race are well documented. Studying these disparities is essential to reduce preventable gun deaths. This study evaluates the relationship between sociodemographic factors and firearms used in gun deaths. MAT ... Full text Link to item Cite

Vaccination after spleen embolization: A practice management guideline from the Eastern Association for the Surgery of Trauma.

Journal Article Injury · November 2022 BACKGROUND: Angioembolization is an important adjunct in the non-operative management of adult trauma patients with splenic injury. Multiple studies have shown that angioembolization may increase the non-operative splenic salvage rate for patients with hig ... Full text Link to item Cite

Restrictive Firearm Laws Are Associated with Decreased Firearm-Related Suicides

Conference Journal of the American College of Surgeons · November 2022 Full text Cite

Hospital change to mixed lipid emulsion from soybean oil-based lipid emulsion for parenteral nutrition in hospitalized and critically ill adults improves outcomes: a pre-post-comparative study.

Journal Article Crit Care · October 18, 2022 INTRODUCTION: Early data suggest use of a mixed lipid emulsion (LE) with a soybean oil reduction strategy in parenteral nutrition (PN) may improve clinical outcomes. Duke University Hospital made a full switch to a Soybean oil/MCT/Olive/Fish Oil lipid (4-O ... Full text Open Access Link to item Cite

Palliative care phenotypes among critically ill patients and family members: intensive care unit prospective cohort study.

Journal Article BMJ Support Palliat Care · September 27, 2022 OBJECTIVE: Because the heterogeneity of patients in intensive care units (ICUs) and family members represents a challenge to palliative care delivery, we aimed to determine if distinct phenotypes of palliative care needs exist. METHODS: Prospective cohort ... Full text Link to item Cite

Underutilization of Acetaminophen in Older Adult Trauma Patients.

Journal Article Am Surg · August 2022 INTRODUCTION: Older adults are more vulnerable to opioid-associated morbidity. The purpose of this study was to determine the frequency and timing of acetaminophen and opioid use in the postoperative period. METHODS: Older adult trauma patients (≥65 years) ... Full text Link to item Cite

Validation of the perioperative nutrition screen for prediction of postoperative outcomes.

Journal Article JPEN J Parenter Enteral Nutr · August 2022 BACKGROUND: Preoperative nutrition risk is often underrecognized and undertreated. The perioperative nutrition screen (PONS) was recently introduced as an efficient tool to rapidly screen for preoperative nutrition risk. The relationship between identifica ... Full text Link to item Cite

Micronutrient deficiencies in critically ill patients receiving continuous renal replacement therapy.

Journal Article Clin Nutr ESPEN · August 2022 BACKGROUND & AIMS: Continuous renal replacement therapy (CRRT) is essential to the management of acute kidney injury (AKI) in critical illness. Unfortunately, large quantities of micronutrients are shown to be lost in CRRT effluent. Current literature desc ... Full text Link to item Cite

Developing a National Trauma Research Action Plan: Results from the geriatric research gap Delphi survey.

Journal Article J Trauma Acute Care Surg · August 1, 2022 BACKGROUND: Treating older trauma patients requires a focus on the confluence of age-related physiological changes and the impact of the injury itself. Therefore, the primary way to improve the care of geriatric trauma patients is through the development o ... Full text Link to item Cite

Trends in Assault Mortalities Among Asian Americans, 2009-2018.

Journal Article J Surg Res · July 2022 INTRODUCTION: As of yet, few studies have described the prevalence or rates of assault mortalities involving Asian victims on a national level. This study aimed to describe yearly trends and regional differences in assault mortalities among Asians. METHODS ... Full text Link to item Cite

Surgical Principles

Chapter · June 30, 2022 Modern medicine has bolstered the life expectancy among older adults, which now averages around 80 years of age in developed nations. Older adults currently make up nearly 17% of the US population, with a projected rise to 25% of all adults in the coming d ... Full text Link to item Cite

Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging.

Journal Article Eur J Trauma Emerg Surg · June 2022 BACKGROUND: The management of complicated ventral hernias (CVH), namely ventral hernias in actively or recently infected/contaminated operative fields, and open abdomens in which the native fascia cannot be primarily reapproximated, pose a surgical challen ... Full text Link to item Cite

Morbidity, Mortality, and Therapeutics in Combined Immunodeficiency: Data From the USIDNET Registry.

Journal Article J Allergy Clin Immunol Pract · May 2022 BACKGROUND: Optimal management of patients with combined immunodeficiency, especially pertaining to hematopoietic stem cell transplantation (HSCT), remains unclear. OBJECTIVE: To identify factors influencing HSCT and mortality in the population with combin ... Full text Link to item Cite

Role of Early Enteral Nutrition in Mechanically Ventilated COVID-19 Patients.

Journal Article Critical care explorations · April 2022 Current guidance recommends initiation of early enteral nutrition (early EN) within 24-36 hours of ICU admission in critically ill COVID-19 patients. Despite this recommendation, there is quite limited evidence describing the effect of early EN on outcomes ... Full text Cite

Improving mortality in older adult trauma patients: Are we doing better?

Journal Article J Trauma Acute Care Surg · February 1, 2022 BACKGROUND: Older adult trauma is associated with high morbidity and mortality. Individuals older than 65 years are expected to make up more than 21% of the total population and almost 39% of trauma admissions by 2050. Our objective was to perform a nation ... Full text Link to item Cite

Assessment of Clinical Palliative Care Trigger Status vs Actual Needs Among Critically Ill Patients and Their Family Members.

Journal Article JAMA Netw Open · January 4, 2022 IMPORTANCE: Palliative care consultations in intensive care units (ICUs) are increasingly prompted by clinical characteristics associated with mortality or resource utilization. However, it is not known whether these triggers reflect actual palliative care ... Full text Link to item Cite

Eleventh International Women in Surgery Career Symposium, February 14-16, 2020 Sand Key Resort, Clearwater Florida.

Journal Article Am Surg · January 2022 Surgery, society, and the world are ever changing. The role of women in surgery is changing too and changing fast. For many women, this change is too slow, too fast, too disruptive, too confusing, and too dependent on others. A symposium such as this helps ... Full text Link to item Cite

Pregnancy inclusion in statewide scarce resource allocation guidelines during COVID-19 pandemic

Conference AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY · 2022 Cite

Trends in Location of Death Among Older Adult Americans After Falls.

Journal Article Gerontol Geriatr Med · 2022 Introduction: Fall-related mortality is increasing among older adults, yet trends and changes in the location of fall-attributed deaths are unknown; additionally, potential disparities are understudied. Methods: To assess trends/factors associated with pla ... Full text Link to item Cite

Antibiotic prophylaxis for tube thoracostomy placement in trauma: a practice management guideline from the Eastern Association for the Surgery of Trauma.

Journal Article Trauma Surg Acute Care Open · 2022 BACKGROUND: Antibiotic prophylaxis is routinely administered for most operative procedures, but their utility for certain bedside procedures remains controversial. We performed a systematic review and meta-analysis and developed evidence-based recommendati ... Full text Link to item Cite

Role of Nutrition in the Elderly Surgical Patient – Review of the Literature and Current Recommendations

Journal Article Current Geriatrics Reports · December 1, 2021 Purpose of Review: Poor nutritional status is common among inpatients, and particularly so among surgical patients. The problem is even more pronounced among elderly surgical patients, with age itself being an independent risk factor for malnutrition. With ... Full text Cite

Racial and Ethnic Differences in Health Care Utilization Following Severe Acute Brain Injury in the United States.

Conference J Intensive Care Med · November 2021 OBJECTIVE: To examine racial and ethnic differences in the utilization of 3 interventions (tracheostomy placement, gastrostomy tube placement, and hospice utilization) among patients with severe acute brain injury (SABI). DESIGN: Retrospective cohort study ... Full text Link to item Cite

Prolonged progressive hypermetabolism during COVID-19 hospitalization undetected by common predictive energy equations.

Journal Article Clin Nutr ESPEN · October 2021 BACKGROUND & AIMS: Indirect calorimetry (IC) is the gold-standard for determining measured resting energy expenditure (mREE) in critical illness. When IC is not available, predicted resting energy expenditure (pREE) equations are commonly utilized, which o ... Full text Link to item Cite

Acute Respiratory Distress Syndrome (ARDS) after trauma: Improving incidence, but increasing mortality.

Journal Article J Crit Care · August 2021 PURPOSE: Acute Respiratory Distress Syndrome (ARDS) is an infrequent, yet morbid inflammatory complication in injury victims. With the current project we sought to estimate trends in incidence, determine outcomes, and identify risk factors for ARDS and rel ... Full text Link to item Cite

Acute Care Resource Use After Elective Surgery in the United States: Implications During the COVID-19 Pandemic.

Journal Article Am J Crit Care · July 1, 2021 BACKGROUND: The COVID-19 pandemic created pressure to delay inpatient elective surgery to increase US health care capacity. This study examined the extent to which common inpatient elective operations consume acute care resources. METHODS: This cross-secti ... Full text Link to item Cite

Field-Triage, Hospital-Triage and Triage-Assessment: A Literature Review of the Current Phases of Adult Trauma Triage.

Journal Article J Trauma Acute Care Surg · June 1, 2021 Despite major improvements in the United States trauma system over the past two decades, prehospital trauma triage is a significant challenge. Undertriage is associated with increased mortality, and overtriage results in significant resource overuse. The A ... Full text Link to item Cite

Echocardiogram Utilization Patterns and Association With Mortality Following Severe Traumatic Brain Injury.

Journal Article Anesth Analg · April 1, 2021 BACKGROUND: Severe traumatic brain injury (TBI) can result in left ventricular dysfunction, which can lead to hypotension and secondary brain injuries. Although echocardiography is often used to examine cardiovascular function in multiple clinical settings ... Full text Open Access Link to item Cite

Improving racial disparities in unmet palliative care needs among intensive care unit family members with a needs-targeted app intervention: The ICUconnect randomized clinical trial.

Journal Article Contemp Clin Trials · April 2021 INTRODUCTION: The technologies used to treat the millions who receive care in intensive care unit (ICUs) each year have steadily advanced. However, the quality of ICU-based communication has remained suboptimal, particularly concerning for Black patients a ... Full text Link to item Cite

Point-Counterpoint: Indirect Calorimetry Is Essential for Optimal Nutrition Therapy in the Intensive Care Unit.

Journal Article Nutr Clin Pract · April 2021 Iatrogenic malnutrition and underfeeding are ubiquitous in intensive care units (ICUs) worldwide for prolonged periods after ICU admission. A major driver leading to the lack of emphasis on timely ICU nutrition delivery is lack of objective data to guide n ... Full text Link to item Cite

Evaluation of malnutrition via modified GLIM criteria for in patients undergoing emergent gastrointestinal surgery.

Journal Article Clin Nutr · March 2021 BACKGROUND: Malnutrition remains a critical public health issue in the US, particularly in surgery where perioperative malnutrition is commonly underdiagnosed and undertreated. In 2016, the Global Leadership Initiative on Malnutrition (GLIM) proposed a set ... Full text Link to item Cite

Association between early postoperative nutritional supplement utilisation and length of stay in malnourished hip fracture patients.

Journal Article Br J Anaesth · March 2021 BACKGROUND: Malnutrition in older hip fracture patients is associated with increased complication rates and mortality. As postoperative nutrition delivery is essential to surgical recovery, postoperative nutritional supplements including oral nutritional s ... Full text Link to item Cite

Histone Deacetylase 3 Associates With Key Regulators of NFκB Signaling in Lung Epithelial Cells Under Stimulation With LPS.

Conference · 2021 Introduction: Histone Deacetylase 3 (HDAC3) is a Class I member of the histone deacetylase family that is recruited to nuclear enhancers. HDAC3 is located within the cell nucleus, where it constitutes the sole endogenous HDAC interacting with the ... Full text Cite

IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages.

Journal Article PLoS One · 2021 INTRODUCTION: Anti-inflammatory cytokine IL-10 suppresses pro-inflammatory IL-12b expression after Lipopolysaccharide (LPS) stimulation in colonic macrophages, as part of the innate immunity Toll-Like Receptor (TLR)-NF-κB activation system. This homeostati ... Full text Link to item Cite

Palliative Care Triggers vs Actual Unmet Needs Among ICU Patients and Family Members

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2021 Cite

The Impact of Nonsteroidal Anti-inflammatory Drugs on Older Adult Trauma Patients With Hip Fractures.

Journal Article J Surg Res · November 2020 BACKGROUND: Nonsteroidal anti-inflammatory drug (NSAID) use is frequently recommended for multimodal analgesia to reduce opioid use. We hypothesized that increased NSAID utilization will decrease opioid requirements without leading to significant complicat ... Full text Link to item Cite

Operationalizing needs-focused palliative care for older adults in intensive care units: Design of and rationale for the PCplanner randomized clinical trial.

Journal Article Contemp Clin Trials · November 2020 INTRODUCTION: The number of older adults who receive life support in an intensive care unit (ICU), now 2 million per year, is increasing while survival remains unchanged. Because the quality of ICU-based palliative care is highly variable, we developed a m ... Full text Link to item Cite

Associations Between Perioperative Crystalloid Volume and Adverse Outcomes in Five Surgical Populations.

Journal Article J Surg Res · July 2020 BACKGROUND: Optimal administration of fluids is an important part of enhanced recovery after surgery (ERAS) protocols. We sought to examine the relationship between perioperative crystalloid volume and adverse outcomes in five common types of surgical proc ... Full text Link to item Cite

Proposal for Coronavirus Disease 2019 Management.

Journal Article Crit Care Explor · May 2020 SETTING: The coronavirus disease 2019 pandemic has raised fear throughout the nation. Current news and social media predictions of ventilator, medication, and personnel shortages are rampant. PATIENTS: Patients with coronavirus disease 2019 are presenting ... Full text Link to item Cite

"I'm Leaving": Factors That Impact Against Medical Advice Disposition Post-Trauma.

Journal Article J Emerg Med · April 2020 BACKGROUND: Discharge against medical advice (AMA) is an important, yet understudied, aspect of health care-particularly in trauma populations. AMA discharges result in increased mortality, increased readmission rates, and higher health care costs. OBJECTI ... Full text Link to item Cite

Dose-Dependent Association of Gabapentinoids with Pulmonary Complications After Total Hip and Knee Arthroplasties.

Journal Article J Bone Joint Surg Am · February 5, 2020 BACKGROUND: Gabapentinoids are commonly prescribed in perioperative multimodal analgesia protocols. Despite widespread use, the optimal dose to reduce opioid consumption while minimizing risks is unknown. We assessed dose-dependent effects of gabapentinoid ... Full text Link to item Cite

Race and Insurance Status as Predictors of Bicycle Trauma Outcome in Adults.

Journal Article J Surg Res · January 2020 BACKGROUND: Race and insurance status have been shown to predict outcomes in pediatric bicycle traumas. It is unknown how these factors influence outcomes in adult bicycle traumas. This study aims to evaluate the association, if any, between race and insur ... Full text Link to item Cite

Acetaminophen, Underutilized in Older Adult Trauma Patients

Conference ANESTHESIA AND ANALGESIA · 2020 Cite

Are Octogenarians and Older Adult Trauma Patients Equivalent

Conference Journal of the American College of Surgeons · October 2019 Full text Cite

Bovine vs Porcine Acellular Dermal Matrix for Abdominal Wall Herniorrhaphy or Bridging

Conference Journal of the American College of Surgeons · October 2019 Full text Cite

The Impact of Race and Socioeconomic Status on Treatment and Outcomes of Blunt Splenic Injury.

Journal Article J Surg Res · August 2019 BACKGROUND: Racial, ethnic, and socioeconomic disparities have been shown to exist in trauma patients. Management of blunt splenic injuries (BSIs) can include splenectomy, embolization, or nonoperative management. This study assesses the effect of race and ... Full text Link to item Cite

Socioeconomic Status Affects Outcomes After Severity-Stratified Traumatic Brain Injury.

Journal Article J Surg Res · March 2019 BACKGROUND: Socioeconomic status (SES) and race have been shown to increase the incidence of being afflicted by a traumatic brain injury (TBI) resulting in worse posthospitalization outcomes. The goal of this study was to determine the effect disparities h ... Full text Link to item Cite

Fractured pediatric central venous catheters - Repair or replace?

Journal Article J Pediatr Surg · January 2019 INTRODUCTION: Central venous catheter (CVC) fracture is a common complication. The aim of this study is to examine risk factors resulting in CVC fracture and compare outcomes of children undergoing CVC repair versus replacement. METHODS: A retrospective ch ... Full text Link to item Cite

Acute Surgical Decision-Making in Abdominal Trauma Is Not Altered by Race or Socioeconomic Status.

Journal Article Am Surg · December 1, 2018 Two main procedures are performed on patients suffering from colonic perforation, diverting colostomy and primary tissue repair. We investigated patient race, ethnicity, and socioeconomic status (SES) that predicted surgical outcomes after blunt or penetra ... Link to item Cite

Effects of Obesity on Penetrating Trauma

Conference Journal of the American College of Surgeons · October 2018 Full text Cite

Predicting Which Patients Will Leave Against Medical Advice

Conference Journal of the American College of Surgeons · October 2018 Full text Cite

Indications for rib fixation

Chapter · September 3, 2018 There are no clear, absolute, and universally accepted indications or contraindications for operative rib fixation. Furthermore, although the majority of experts believe patients benefit most from early operative fixation, there is no consensus agreement r ... Full text Cite

Rib Fracture Location Should Be Evaluated When Predicting Morbidity and Mortality in Trauma Patients.

Conference Am Surg · September 1, 2018 Rib fractures represent up to 55 per cent of thoracic blunt traumatic injuries and lead to significant mortality and morbidity. The aim of this study is to determine whether not only number but also the location of rib fractures can be used to risk stratif ... Link to item Cite

Barriers to Hospice Care in Trauma Patients: The Disparities in End-of-Life Care.

Journal Article Am J Hosp Palliat Care · August 2018 INTRODUCTION: End-of-life and palliative care are important aspects of trauma care and are not well defined. This analysis evaluates the racial and socioeconomic disparities in terms of utilization of hospice services for critically ill trauma patients. ME ... Full text Link to item Cite

Socioeconomics affecting quality outcomes in Asian trauma patients within the United States.

Journal Article J Surg Res · August 2018 INTRODUCTION: Asian-Americans and Pacific Islanders are often considered as a uniform group when examining race in health outcomes. However, the generally favorable economic outcomes in this group belie significant socioeconomic variance between its hetero ... Full text Link to item Cite

Socioeconomic disparities in the thoracic trauma population.

Journal Article J Surg Res · April 2018 BACKGROUND: Health-care disparities based on socioeconomic status have been well documented in the trauma literature; however, there is a paucity of data on how these factors affect outcomes in patients experiencing severe thoracic trauma. This study aims ... Full text Link to item Cite

Using epistemic network analysis to identify targets for educational interventions in trauma team communication.

Journal Article Surgery · April 2018 BACKGROUND: Epistemic Network Analysis (ENA) is a technique for modeling and comparing the structure of connections between elements in coded data. We hypothesized that connections among team discourse elements as modeled by ENA would predict the quality o ... Full text Link to item Cite

Race, insurance status, and traumatic brain injury outcomes before and after enactment of the Affordable Care Act.

Journal Article Surgery · February 2018 BACKGROUND: The Affordable Care Act aims to improve patient outcomes. Race/ethnicity and insurance status impact outcomes after traumatic brain injury. We sought to gauge the Affordable Care Act's effect on outcomes after traumatic brain injury, as graded ... Full text Link to item Cite

Why saying what you mean matters: An analysis of trauma team communication.

Journal Article Am J Surg · February 2018 BACKGROUND: We hypothesized that team communication with unmatched grammatical form and communicative intent (mixed mode communication) would correlate with worse trauma teamwork. METHODS: Interdisciplinary trauma simulations were conducted. Team performan ... Full text Link to item Cite

Predicting Liver Failure in Patients Undergoing Partial Hepatectomy

Conference Journal of the American College of Surgeons · October 2017 Full text Cite

Laparo-endoscopic single-site (LESS) cholecystectomy with epidural vs. general anesthesia.

Journal Article Surg Endosc · May 2013 BACKGROUND: Laparo-endoscopic single-site (LESS) surgery involves a single umbilical incision, lending itself to epidural anesthesia. This prospective, randomized study was undertaken to evaluate epidural anesthesia for patients undergoing LESS cholecystec ... Full text Link to item Cite

Postoperative hypoxemia: common, undetected, and unsuspected after bariatric surgery.

Journal Article J Surg Res · April 2010 BACKGROUND: Patients undergoing gastric bypass are at greater than ordinary risk for postoperative respiratory insufficiency, presumably related to obstructive sleep apnea (OSA) and patient-controlled analgesia (PCA). This study was proposed to quantify th ... Full text Link to item Cite

Incidence of bone loss, falls, and fractures after Roux-en-Y gastric bypass for morbid obesity.

Journal Article Appl Nurs Res · February 2009 The objectives of this study were to determine the incidence of and associated risks for falls and fractures after gastric bypass surgery for morbid obesity and to determine the clinical signs of bone loss. The sample consisted of 167 individuals at a mean ... Full text Link to item Cite

Trends in adrenalectomy rates, indications, and physician volume: A statewide analysis of 1816 adrenalectomies.

Journal Article Surgery · December 2007 BACKGROUND: Adrenalectomy rates seem to be increasing in Florida, possibly due to increased availability of laparoscopic adrenalectomy, identification of incidentalomas, and access to care for minorities. We hypothesized that the rate of adrenalectomies in ... Full text Link to item Cite

Morbidity of anastomotic leaks in patients undergoing Roux-en-Y gastric bypass.

Journal Article Arch Surg · October 2007 OBJECTIVE: To document the effect of anastomotic leaks on morbidity and mortality after Roux-en-Y gastric bypass (RYGB) for obesity. DESIGN: Prospectively collected data on 840 consecutive patients who underwent RYGB between 1998 and 2005. Multivariate log ... Full text Link to item Cite

A state-wide review of contemporary outcomes of gastric bypass in Florida: does provider volume impact outcomes?

Journal Article Ann Surg · May 2007 OBJECTIVES: To report contemporary outcomes of gastric bypass for obesity and to assess the relationship between provider volume and outcomes. BACKGROUND: Certain Florida-based insurers are denying patients access to bariatric surgery because of alleged hi ... Full text Link to item Cite

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Journal Article Surgery for Obesity and Related Diseases · May 2007 Full text Cite

Incidence of falls, fractures and injuries following Roux-en-Y gastric bypass surgery

Journal Article Journal of Clinical Densitometry · April 2007 Full text Cite

Objective evidence that bariatric surgery improves obesity-related obstructive sleep apnea.

Journal Article Surgery · March 2007 BACKGROUND: Obstructive sleep apnea (OSA) is associated with obesity. Our aim in this study is to report objective improvement of obesity-related OSA and sleep quality after bariatric surgery. METHODS: Prospective bariatric patients were referred for polys ... Full text Link to item Cite

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Journal Article Journal of Surgical Research · February 2007 Full text Cite

P18

Journal Article Journal of Surgical Research · February 2007 Full text Cite

Bariatric surgery improves urinary incontinence in morbidly obese individuals.

Journal Article Surg Obes Relat Dis · 2007 BACKGROUND: Urinary incontinence is common in obese individuals. We report on the prevalence of urinary incontinence in patients undergoing bariatric surgery and the effect of surgically induced weight loss on urinary incontinence. METHODS: The prospective ... Full text Link to item Cite

Does experience preclude leaks in laparoscopic gastric bypass?

Journal Article Surg Endosc · November 2006 BACKGROUND: Improved outcomes of laparoscopic Roux-en-Y gastric bypass (LRYGB) have been demonstrated once pratice has moved beyond the learning curve. However, there is no evidence that experience has a favorable impact on the incidence of leaks. This stu ... Full text Link to item Cite

The role of p65 NF-kappaB/RelA in pancreatitis-induced Kupffer cell apoptosis.

Journal Article J Gastrointest Surg · June 2006 Acute pancreatitis induces liver injury by upregulating Kupffer cell-derived Fas/FasL; on the other hand, acute pancreatitis induces apoptosis of Kupffer cells via NF-kappaB-dependent pathways. The balance between upregulation of Fas/FasL and Fas/FasL-indu ... Full text Link to item Cite

The role of NO and TNF in pancreatitis-induced ileus

Journal Article Journal of Surgical Research · February 2006 Full text Cite

Outcomes of bariatric surgery in patients > or =65 years.

Journal Article Surg Obes Relat Dis · 2006 BACKGROUND: Although the Medicare Coverage Advisory Committee found that significant evidence supports the safety and effectiveness of bariatric surgery, few data are available on the outcomes of bariatric procedures in patients > or =65 years. The aim of ... Full text Link to item Cite

Spectrum and treatment of small bowel obstruction after Roux-en-Y gastric bypass.

Journal Article Surg Obes Relat Dis · 2006 BACKGROUND: Small bowel obstruction (SBO) is a well-recognized complication of bariatric surgery. Many factors that play a role in the etiology of SBO affect the presentation, timing, and treatment after Roux-en-Y gastric bypass (RYGB). We reviewed our exp ... Full text Link to item Cite

Predictive factors of thromboembolic events in patients undergoing Roux-en-Y gastric bypass.

Journal Article Surg Obes Relat Dis · 2006 BACKGROUND: Obesity is a major risk factor for postoperative deep venous thrombosis (DVT) and pulmonary embolism (PE). Identifying those patients at the greatest risk for DVT/PE is essential to prevent thromboembolic events among patients undergoing Roux-e ... Full text Link to item Cite

Nuclear factor-kappaB mediates Kupffer cell apoptosis through transcriptional activation of Fas/FasL.

Conference J Surg Res · January 2006 INTRODUCTION: Nuclear factor (NF)-kappaB is a key transcriptional factor for cell survival, inflammation, and stress response. We demonstrated that Kupffer cell-derived FasL plays a central role in pancreatitis-induced hepatocyte injury. The aim of this st ... Full text Link to item Cite

Amelioration of gastroesophageal reflux symptoms following Roux-en-Y gastric bypass for clinically significant obesity.

Journal Article Am Surg · November 2005 Symptoms of gastroesophageal reflux disease (GERD) are frequent in patients with clinically significant obesity and are reported to improve after Roux-en-Y gastric bypass (RYGB). The purpose of this study is to determine timing and duration of improvement ... Link to item Cite

Operative technique for converting a failed vertical banded gastroplasty to Roux-en-Y gastric bypass.

Journal Article J Am Coll Surg · September 2005 BACKGROUND: Bariatric surgeons are increasingly encountering patients with failed weight-loss operations. Conversion from vertical banded gastroplasty (VBG) to Roux-en-Y gastric bypass (RYGB) is the most common revisional operation in our practice. We revi ... Full text Link to item Cite

Current indications for preoperative inferior vena cava filter insertion in patients undergoing surgery for morbid obesity.

Conference Obes Surg · August 2005 BACKGROUND: Pulmonary embolus is a potentially lethal complication in patients undergoing surgery for morbid obesity. In a select group of patients at high risk for venous thromboembolic events (VTE), we have chosen to prophylactically insert inferior vena ... Full text Link to item Cite

Realistic expectations and leadership in the era of work hour reform.

Conference J Surg Res · June 15, 2005 BACKGROUND: Work hour guidelines and core competencies were introduced to improve surgical education and are changing the landscape of surgical training. We sought to examine perceptions and attitudes regarding the impetus and impact associated with these ... Full text Link to item Cite

Safety and efficacy of bariatric surgery in patients 65 years and older

Journal Article Surgery for Obesity and Related Diseases · May 2005 Full text Cite

Added morbidity after anastomotic leaks in patients undergoing Roux-en-Y gastric bypass

Journal Article Surgery for Obesity and Related Diseases · May 2005 Full text Cite

Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosis.

Journal Article J Gastrointest Surg · April 2005 Liver injury is a clinical prognostic indicator in acute pancreatitis (AP). We have demonstrated that Kupffer cell-derived FasL mediates liver injury during AP and sought to determine its role in AP-induced hepatocyte apoptosis. AP was induced in National ... Full text Link to item Cite

Acute pancreatitis induces FasL gene expression and apoptosis in the liver.

Conference J Surg Res · December 2004 BACKGROUND: Liver injury is an important prognostic indicator in acute pancreatitis. We previously demonstrated that Kupffer cell-derived cytokines mediate liver injury. In this work, we sought to characterize the role of Fas Ligand (FasL) in liver injury ... Full text Link to item Cite

Management of incidental ovarian tumors in patients undergoing gastric bypass.

Journal Article Obes Surg · October 2004 BACKGROUND: Ovarian disease is common in obese women and is usually not screened during routine preoperative evaluation in patients undergoing bariatric surgery. Consequently, surgeons may encounter previously undiagnosed adnexal tumors during bariatric op ... Full text Link to item Cite

Kupffer cell-derived Fas ligand plays a role in liver injury and hepatocyte death.

Journal Article J Gastrointest Surg · February 2004 Liver injury is an important prognostic indicator during acute pancreatitis. The aim of this study was to determine the role of Fas ligand (FasL) in hepatocyte injury. Liver parenchymal enzymes were measured in cocultures of hepatocytes and Kupffer cells t ... Full text Link to item Cite

The importance of routine liver biopsy in diagnosing nonalcoholic steatohepatitis in bariatric patients.

Conference Obes Surg · January 2004 BACKGROUND: Nonalcoholic Steatohepatitis (NASH) commonly occurs in obese patients and predisposes to cirrhosis. Prevalence of NASH in bariatric patients is unknown. Our aim was to determine the role of routine liver biopsy in managing bariatric patients. M ... Full text Link to item Cite

1.

Journal Article American Society of Mechanical Engineers (Paper) · December 1, 1979 The average flow model presented by Patir and Cheng is evaluated. First, it is shown that the choice of grid used in the average flow model influences the results. The results presented are different from those given by Patir and Cheng. Second, it is shown ... Cite