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Pao-Hwa Lin

Pao-Hwa Lin

Professor in Medicine
Medicine, Nephrology
lin00004@mc.duke.edu
Duke Box 3487, Durham, NC 27710
3475 Erwin Road Suite 100, Stedman Nutrition Center, Durham, NC 27705

Selected Publications

Mental health needs and barriers to service in the Chinese American community: insights gained from focus groups.

Journal Article Ethn Health · November 2024 OBJECTIVES: Mental health remains an unmet need among Chinese Americans. This study aims to identify specific needs and strategies that may address the needs. DESIGN: A total of 55 Chinese Americans consented and participated in online focus groups conduct ... Full text Link to item Cite

Longitudinal Pilot Evaluation of the Gut Microbiota Comparing Patients With and Without Chronic Kidney Disease.

Journal Article J Ren Nutr · July 2024 OBJECTIVE: The gut microbiota contributes to metabolic diseases, such as diabetes and hypertension, but is poorly characterized in chronic kidney disease (CKD). DESIGN AND METHODS: We enrolled 24 adults within household pairs, in which at least one member ... Full text Link to item Cite

Metabolic Response to Androgen Deprivation Therapy of Prostate Cancer.

Journal Article Cancers (Basel) · May 24, 2024 Prostate cancer (PC) stands as the most frequently diagnosed non-skin cancer and ranks as the second highest cause of cancer-related deaths among men in the United States. For those facing non-metastatic PC necessitating intervention, solely local treatmen ... Full text Link to item Cite

Effects of Chinese heart-healthy diet on blood lipids, glucose, and estimated 10-y cardiovascular disease risk among Chinese adults: results on secondary outcomes of a randomized controlled trial.

Journal Article Am J Clin Nutr · February 2024 BACKGROUND: Healthy diet is essential for cardiovascular disease risk management, but its effects among Chinese patients, whose diets differ from Western diets, remain largely unknown. METHODS: In this multicenter, patient- and outcome assessor-blind, rand ... Full text Link to item Cite

Effects of Lifestyle Modification on Psychosocial Function in Patients With Resistant Hypertension: SECONDARY OUTCOMES FROM THE TRIUMPH RANDOMIZED CLINICAL TRIAL.

Journal Article J Cardiopulm Rehabil Prev · January 1, 2024 PURPOSE: In a secondary analysis of the TRIUMPH clinical trial, psychological outcomes in patients with resistant hypertension (RH) receiving a diet and exercise intervention delivered in a cardiac rehabilitation setting were compared with those receiving ... Full text Link to item Cite

A Proposal for the Comprehensive Care of Men on Androgen Deprivation Therapy: Recommendations from the Multidisciplinary Prostate Cancer 360 Working Group

Journal Article Urology Practice · January 1, 2024 Introduction:To promote comprehensive care of patients throughout the androgen deprivation therapy (ADT) prescribing process, the Prostate Cancer 360 (PC360) Working Group developed monitoring and management recommendations intended to mitigate or prevent ... Full text Cite

Sustainable Participation in Community Health Programs to Promote a Healthy Lifestyle and Prevent and Protect against Dementia among Rural Taiwanese Middle-Aged and Older Adults.

Journal Article J Prev Alzheimers Dis · 2024 BACKGROUND: Resource and economic constraints limit access to health care in rural populations, and consequently, rates of chronic illnesses are higher in this population. Further, little is known about how rural populations adopt active and healthy lifest ... Full text Link to item Cite

Modern perspective of the Rice Diet for hypertension and other metabolic diseases.

Journal Article BMJ Nutr Prev Health · 2024 BACKGROUND: In the early 1940s, before antihypertensive drugs were available, the Rice Diet Programme (RDP) was developed to treat severe hypertension and, later, diabetes and obesity. Despite significant advancements in dietary management for these condit ... Full text Link to item Cite

Supplement use and gastric cancer risk in the Southern Community Cohort Study.

Journal Article Cancer Causes Control · October 2023 PURPOSE: Gastric cancer remains a racial health disparity in the US, but few studies have examined supplements as a potential protective factor. We examined associations between regular supplement use and gastric cancer risk among the predominantly Black p ... Full text Link to item Cite

Diversity of plant DNA in stool is linked to dietary quality, age, and household income.

Journal Article Proc Natl Acad Sci U S A · July 4, 2023 Eating a varied diet is a central tenet of good nutrition. Here, we develop a molecular tool to quantify human dietary plant diversity by applying DNA metabarcoding with the chloroplast trnL-P6 marker to 1,029 fecal samples from 324 participants across two ... Full text Link to item Cite

The Streaming Web-Based Exercise at Home Study for Breast and Prostate Cancer Survivors: A Feasibility Study Protocol.

Journal Article Methods Protoc · May 17, 2023 BACKGROUND: Despite the known benefits of physical activity in cancer survivors, adherence to exercise guidelines remains low. Known barriers to adhering to guidelines include a lack of time and an unwillingness to return to treatment facilities. Virtual e ... Full text Link to item Cite

Identifying the behavior change techniques used in obesity interventions: An example from the EARLY trials

Journal Article Obesity Science and Practice · April 1, 2023 Objective: The dissemination of effective obesity interventions requires the documentation of key elements of the intervention. But outcome papers and other published manuscripts often lack detail that allow the replication of the intervention. The Behavio ... Full text Cite

Self-Perceived Barriers and Facilitators to Dietary Approaches to Stop Hypertension Diet Adherence Among Black Americans With Chronic Kidney Disease: A Qualitative Study.

Journal Article J Ren Nutr · January 2023 OBJECTIVE: The Dietary Approaches to Stop Hypertension (DASH) eating plan improves hypertension in Black individuals and is associated with favorable chronic kidney disease (CKD) outcomes. Yet, adherence to DASH is low among US adults in general, particula ... Full text Link to item Cite

Inflammation moderates the effects of lifestyle modification on neurocognition among individuals with resistant hypertension.

Journal Article J Clin Hypertens (Greenwich) · January 2023 Individuals with resistant hypertension (RH) have the greatest risk of cerebrovascular disease and cognitive impairment among individuals with hypertension. Elevated levels of pro-inflammatory cytokines may represent a critical yet unexamined factor influe ... Full text Link to item Cite

Responses to mental health issues among Chinese American Christian communities: report from focus group conversations

Journal Article Mental Health, Religion and Culture · January 1, 2023 Religious and cultural factors play an important part in shaping attitudes about mental health. This study focuses on mental health-related beliefs of a specific ethnocultural population: Chinese American Christians. Using an online adaptation of nominal g ... Full text Cite

The DASH Dietary Pattern

Chapter · January 1, 2023 Strong evidence supports the blood pressure lowering effect of the DASH dietary pattern and its long-term benefit on risk of hypertension and cardiovascular disease, including stroke. Observational evidence suggests that the DASH dietary pattern may be ben ... Full text Cite

Weight loss via a low-carbohydrate diet improved the intestinal permeability marker, zonulin, in prostate cancer patients.

Journal Article Ann Med · December 2022 BACKGROUND: Accumulating evidence suggest that gut microbiota may impact urologic health including prostate cancer (PC), potentially via affecting intestinal permeability (IP). Studies have indicated that disrupted IP may be improved by healthy diets and w ... Full text Link to item Cite

Bioavailability of phosphorus and kidney function in the Jackson Heart Study.

Journal Article Am J Clin Nutr · August 4, 2022 BACKGROUND: High phosphorus (P) exposure may have negative effects on kidney function. Nutrient databases provide total P, but bioavailability varies by source. OBJECTIVES: We aimed to assess natural, added, and bioavailable P intake, and to relate these t ... Full text Link to item Cite

Effects of Cuisine-Based Chinese Heart-Healthy Diet in Lowering Blood Pressure Among Adults in China: Multicenter, Single-Blind, Randomized, Parallel Controlled Feeding Trial.

Journal Article Circulation · July 26, 2022 BACKGROUND: More than one-fifth of the world's population consumes Chinese cuisines regularly, but no evidence-based healthy diets fitting the Chinese food culture are available for implementation. METHODS: A multicenter, patient- and outcome assessor-blin ... Full text Link to item Cite

Lifestyle modification and cognitive function among individuals with resistant hypertension: cognitive outcomes from the TRIUMPH trial.

Journal Article J Hypertens · July 1, 2022 BACKGROUND: Resistant hypertension is associated with increased risk of cognitive decline, stroke, and dementia. Lifestyle modification has been suggested to improve cognitive function through its salutary effects on vascular function. METHODS: Participant ... Full text Link to item Cite

Microbiota responses to different prebiotics are conserved within individuals and associated with habitual fiber intake.

Journal Article Microbiome · July 2022 BackgroundShort-chain fatty acids (SCFAs) derived from gut bacteria are associated with protective roles in diseases ranging from obesity to colorectal cancers. Intake of microbially accessible dietary fibers (prebiotics) lead to varying effects o ... Full text Cite

Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveals the potential role of ketogenesis to slow tumor growth: a secondary analysis of the CAPS2 diet trial.

Journal Article Prostate Cancer Prostatic Dis · April 2022 BACKGROUND: Systemic treatments for prostate cancer (PC) have significant side effects. Thus, newer alternatives with fewer side effects are urgently needed. Animal and human studies suggest the therapeutic potential of low carbohydrate diet (LCD) for PC. ... Full text Open Access Link to item Cite

Cerebrovascular Function, Vascular Risk, and Lifestyle Patterns in Resistant Hypertension.

Journal Article J Alzheimers Dis · 2022 BACKGROUND: Impaired cerebrovascular reactivity (CVR) and blunted cerebral hemodynamic recruitment are thought to be important mechanisms linking hypertension to cerebrovascular and cognitive outcomes. Few studies have examined cardiovascular or dietary co ... Full text Link to item Cite

The DASH Dietary Pattern

Chapter · January 1, 2022 The Dietary Approaches to Stop Hypertension (DASH) dietary pattern was proven to reduce both systolic and diastolic blood pressure (BP) significantly and effectively in multiple large-scale clinical trials. The magnitude of BP reduction was similar to that ... Full text Cite

Low Carbohydrate Diets and Estimated Cardiovascular and Metabolic Syndrome Risk in Prostate Cancer.

Journal Article J Urol · December 2021 PURPOSE: A low carbohydrate diet (LCD) was shown to suggestively slow prostate cancer (PC) growth. In noncancer patients, LCDs improve metabolic syndrome (MetS) without weight loss. However, concerns about negative impact on cardiovascular disease (CVD) ri ... Full text Link to item Cite

Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial.

Journal Article Circulation · October 12, 2021 BACKGROUND: Although lifestyle modifications generally are effective in lowering blood pressure (BP) among patients with unmedicated hypertension and in those treated with 1 or 2 antihypertensive agents, the value of exercise and diet for lowering BP in pa ... Full text Link to item Cite

Effect of Bicarbonate on Net Acid Excretion, Blood Pressure, and Metabolism in Patients With and Without CKD: The Acid Base Compensation in CKD Study.

Journal Article Am J Kidney Dis · July 2021 RATIONALE & OBJECTIVE: Patients with CKD are at elevated risk of metabolic acidosis due to impaired net acid excretion (NAE). Identifying early markers of acidosis may guide prevention in chronic kidney disease (CKD). This study compared NAE in participant ... Full text Link to item Cite

The influence of low-carbohydrate diets on the metabolic response to androgen-deprivation therapy in prostate cancer.

Journal Article Prostate · July 2021 BACKGROUND: Prostate cancer (PC) is the second most lethal cancer for men. For metastatic PC, standard first-line treatment is androgen deprivation therapy (ADT). While effective, ADT has many metabolic side effects. Previously, we found in serum metabolom ... Full text Link to item Cite

Urine and Plasma Metabolome of Healthy Adults Consuming the DASH (Dietary Approaches to Stop Hypertension) Diet: A Randomized Pilot Feeding Study.

Journal Article Nutrients · May 22, 2021 We aimed to identify plasma and urine metabolites altered by the Dietary Approaches to Stop Hypertension (DASH) diet in a post-hoc analysis of a pilot feeding trial. Twenty adult participants with un-medicated hypertension consumed a Control diet for one w ... Full text Link to item Cite

Public interest in dietary supplements for prostate cancer prevention.

Journal Article Prostate Cancer Prostatic Dis · March 2021 Full text Link to item Cite

Protocol of a multicenter, single-blind, randomised, parallel controlled feeding trial evaluating the effect of a Chinese Healthy Heart (CHH) diet in lowering blood pressure and other cardiovascular risk factors.

Journal Article BMJ Open · August 20, 2020 INTRODUCTION: Unhealthy diet has been identified as the number one attributor of total mortality in China, accounting for more than 20% of total deaths. Although the Dietary Approach to Stop Hypertension (DASH) and Mediterranean diets have been proven bene ... Full text Link to item Cite

Preliminary evidence of effects of potassium chloride on a metabolomic path to diabetes and cardiovascular disease.

Journal Article Metabolomics · June 18, 2020 INTRODUCTION: Low potassium intake can affect cardiovascular disease (CVD) risk and cardiometabolic risk factors. OBJECTIVE: We hypothesize that potassium chloride (KCl) supplementation can improve cardiovascular risk metabolomic profile. METHODS: In this ... Full text Link to item Cite

A Randomized Controlled Trial of a 6-Month Low-Carbohydrate Intervention on Disease Progression in Men with Recurrent Prostate Cancer: Carbohydrate and Prostate Study 2 (CAPS2).

Journal Article Clin Cancer Res · June 15, 2020 PURPOSE: Both weight loss and low-carbohydrate diets (LCD) without weight loss prolong survival in prostate cancer models. Few human trials have tested weight loss or LCD on prostate cancer. EXPERIMENTAL DESIGN: We conducted a multi-site randomized 6-month ... Full text Link to item Cite

Metabolomic effects of androgen deprivation therapy treatment for prostate cancer.

Journal Article Cancer Med · June 2020 Androgen deprivation therapy (ADT) is the main treatment strategy for men with metastatic prostate cancer (PC). However, ADT is associated with various metabolic disturbances, including impaired glucose tolerance, insulin resistance and weight gain, increa ... Full text Link to item Cite

Longer Term Effects of Diet and Exercise on Neurocognition: 1-Year Follow-up of the ENLIGHTEN Trial.

Journal Article J Am Geriatr Soc · March 2020 OBJECTIVES: To evaluate the longer term changes in executive functioning among participants with cardiovascular disease (CVD) risk factors and cognitive impairments with no dementia (CIND) randomized to a diet and exercise intervention. DESIGN: A 2 (Exerci ... Full text Link to item Cite

Project PLACE: Enhancing community and academic partnerships to describe and address health disparities.

Chapter · 2020 Achieving cancer health equity is a national imperative. Cancer is the second leading cause of death in the United States and in North Carolina (NC), where the disease disproportionately impacts traditionally underrepresented race and ethnic groups, those ... Full text Link to item Cite

Metabolic and Neurocognitive Changes Following Lifestyle Modification: Examination of Biomarkers from the ENLIGHTEN Randomized Clinical Trial.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Previous studies have demonstrated that aerobic exercise (AE) and the Dietary Approaches to Stop Hypertension (DASH) diet can improve neurocognition. However, the mechanisms by which lifestyle improves neurocognition have not been widely studie ... Full text Link to item Cite

The DASH Dietary Pattern

Chapter · January 1, 2020 The Dietary Approaches to Stop Hypertension (DASH) diet is an evidence-based dietary pattern that is effective in lowering blood pressure, improving lipids, and achieving weight control among individuals with hypertension. The blood pressure-lowering benef ... Full text Cite

Dietary inflammatory index (DII) and risk of prostate cancer in a case-control study among Black and White US Veteran men.

Journal Article Prostate Cancer Prostatic Dis · December 2019 BACKGROUND: We hypothesized a pro-inflammatory diet would be associated with higher prostate cancer (PC) risk. METHODS: We prospectively recruited incident PC cases (n = 254) and controls (n = 328) at the Durham Veteran Affairs, from 2007 to 2018. From a s ... Full text Link to item Cite

DASH Diet and Blood Pressure Among Black Americans With and Without CKD: The Jackson Heart Study.

Journal Article Am J Hypertens · September 24, 2019 BACKGROUND: The Dietary Approaches to Stop Hypertension (DASH) diet lowers blood pressure (BP) more effectively in blacks compared to other US racial subgroups. Considering chronic kidney disease (CKD) raises BP through complex mechanisms, DASH may affect ... Full text Link to item Cite

A lifestyle intervention of weight loss via a low-carbohydrate diet plus walking to reduce metabolic disturbances caused by androgen deprivation therapy among prostate cancer patients: carbohydrate and prostate study 1 (CAPS1) randomized controlled trial.

Journal Article Prostate Cancer Prostatic Dis · September 2019 PURPOSE: The objective of this study was to test a low-carbohydrate diet (LCD) plus walking to reduce androgen deprivation therapy (ADT)-induced metabolic disturbances. MATERIALS AND METHODS: This randomized multi-center trial of prostate cancer (PCa) pati ... Full text Open Access Link to item Cite

Deconstructing Weight Management Interventions for Young Adults: Looking Inside the Black Box of the EARLY Consortium Trials.

Journal Article Obesity (Silver Spring) · July 2019 OBJECTIVE: The goal of the present study was to deconstruct the 17 treatment arms used in the Early Adult Reduction of weight through LifestYle (EARLY) weight management trials. METHODS: Intervention materials were coded to reflect behavioral domains and b ... Full text Link to item Cite

An update of research evidence on nutrition and prostate cancer.

Journal Article Urol Oncol · June 2019 BACKGROUND: Prostate cancer (PCa) remains a leading cause of mortality in US and other countries. Preclinical and clinical studies have examined the role of nutrition and dietary intake on the incidence and progression of PCa with mixed results. OBJECTIVE: ... Full text Link to item Cite

Lifestyle and neurocognition in older adults with cognitive impairments: A randomized trial.

Journal Article Neurology · January 15, 2019 OBJECTIVE: To determine the independent and additive effects of aerobic exercise (AE) and the Dietary Approaches to Stop Hypertension (DASH) diet on executive functioning in adults with cognitive impairments with no dementia (CIND) and risk factors for car ... Full text Link to item Cite

Dietary intake and prostate cancer, continued pursuit for evidence

Journal Article Translational Andrology and Urology · January 1, 2019 Full text Cite

Accuracy and congruence of physician and adolescent patient weight-related discussions: Teen CHAT (Communicating health: Analyzing talk).

Journal Article Patient Educ Couns · December 2018 OBJECTIVE: We assessed the accuracy and congruence of recall of weight topics during clinical encounters between adolescent patients with overweight/obesity and physicians (randomized to Motivational Interviewing education vs. control arm). METHODS: We aud ... Full text Link to item Cite

The Association Between Engagement and Weight Loss Through Personal Coaching and Cell Phone Interventions in Young Adults: Randomized Controlled Trial.

Journal Article JMIR Mhealth Uhealth · October 18, 2018 BACKGROUND: Understanding how engagement in mobile health (mHealth) weight loss interventions relates to weight change may help develop effective intervention strategies. OBJECTIVE: This study aims to examine the (1) patterns of participant engagement over ... Full text Open Access Link to item Cite

Physician Weight-Related Counseling Is Unrelated to Extreme Weight Loss Behaviors Among Overweight and Obese Adolescents.

Journal Article Clin Pediatr (Phila) · July 2018 Some physicians may be hesitant to counsel overweight and obese adolescents about weight because of concerns that such counseling may result in extreme weight loss behaviors and the subsequent development of eating disorders. We compared self-reported extr ... Full text Link to item Cite

The Association Between Engagement and Weight Loss Through Personal Coaching and Cell Phone Interventions in Young Adults: Randomized Controlled Trial (Preprint)

Journal Article · March 22, 2018 BACKGROUNDUnderstanding how engagement in mobile health (mHealth) weight loss interventions relates to weight change may help develop effective intervention strategies. ... Full text Open Access Cite

Ambulatory blood pressure in the dash diet trial: Effects of race and albuminuria.

Journal Article J Clin Hypertens (Greenwich) · February 2018 We evaluated whether low-grade albuminuria or black race modulates ambulatory blood pressure (BP) or nocturnal BP response to the DASH diet. Among 202 adults enrolled in the DASH multicenter trial who were fed the DASH or control diet for 8 weeks, reductio ... Full text Link to item Cite

Effects of potassium supplements on glucose metabolism in African Americans with prediabetes: a pilot trial.

Journal Article Am J Clin Nutr · December 2017 Background: Low potassium has been identified both as a risk factor for type 2 diabetes and as a mediator of the racial disparity in diabetes risk. Low potassium could be a potentially modifiable risk factor, particularly for African Americans.Objective: W ... Full text Link to item Cite

Serum potassium is a predictor of incident diabetes in African Americans with normal aldosterone: the Jackson Heart Study.

Journal Article Am J Clin Nutr · February 2017 BACKGROUND: Low-normal potassium is a risk factor for diabetes and may account for some of the racial disparity in diabetes risk. Aldosterone affects serum potassium and is associated with insulin resistance. OBJECTIVES: We sought to confirm the associatio ... Full text Open Access Link to item Cite

Lifestyle and Neurocognition in Older Adults With Cardiovascular Risk Factors and Cognitive Impairment.

Journal Article Psychosom Med · 2017 OBJECTIVE: The aim of the study was to determine the relationship of lifestyle factors and neurocognitive functioning in older adults with vascular risk factors and cognitive impairment, no dementia (CIND). METHODS: One hundred sixty adults (M [SD] = 65.4 ... Full text Link to item Cite

Nutrition, lifestyle, and hypertension

Chapter · January 1, 2017 Hypertension is a major risk factor for coronary heart disease, stroke, and premature death and a leading risk factor for global disease burden. Prevalence for those 18 years and older in the United States has remained around 29% since 1999 with little imp ... Full text Cite

Teaching primary care physicians the 5 A's for discussing weight with overweight and obese adolescents.

Journal Article Patient Educ Couns · October 2016 OBJECTIVE: We developed an online intervention to teach physicians both MI (addressed in outcomes paper) and the 5 A's (Ask, Advise, Assess, Assist, and Arrange) when discussing weight with overweight/obese adolescents. METHODS: We audio recorded 527 encou ... Full text Link to item Cite

Short-term effects of the DASH diet in adults with moderate chronic kidney disease: a pilot feeding study.

Journal Article Clin Kidney J · August 2016 BACKGROUND: Although the Dietary Approaches to Stop Hypertension (DASH) diet lowers blood pressure (BP) for adults with normal kidney function, evidence is lacking regarding its safety and efficacy in chronic kidney disease (CKD). We aimed to test the effe ... Full text Open Access Link to item Cite

Teaching Physicians Motivational Interviewing for Discussing Weight With Overweight Adolescents.

Journal Article J Adolesc Health · July 2016 PURPOSE: We tested whether an online intervention combined with a patient feedback report improved physicians' use of motivational interviewing (MI) techniques when discussing weight with overweight and obese adolescents. METHODS: We randomized 46 pediatri ... Full text Link to item Cite

Adaptive intervention design in mobile health: Intervention design and development in the Cell Phone Intervention for You trial.

Journal Article Clin Trials · December 2015 BACKGROUND/AIMS: The obesity epidemic has spread to young adults, and obesity is a significant risk factor for cardiovascular disease. The prominence and increasing functionality of mobile phones may provide an opportunity to deliver longitudinal and scala ... Full text Open Access Link to item Cite

Lifestyle modification for resistant hypertension: The TRIUMPH randomized clinical trial.

Journal Article Am Heart J · November 2015 BACKGROUND: Resistant hypertension (RH) is a growing health burden in this country affecting as many as 1 in 5 adults being treated for hypertension. Resistant hypertension is associated with increased risk of adverse cardiovascular disease (CVD) events an ... Full text Link to item Cite

Cell phone intervention for you (CITY): A randomized, controlled trial of behavioral weight loss intervention for young adults using mobile technology.

Journal Article Obesity (Silver Spring) · November 2015 OBJECTIVE: To determine the effect on weight of two mobile technology-based (mHealth) behavioral weight loss interventions in young adults. METHODS: Randomized, controlled comparative effectiveness trial in 18- to 35-year-olds with BMI ≥ 25 kg/m(2) (overwe ... Full text Open Access Link to item Cite

Nutrition, dietary interventions and prostate cancer: the latest evidence.

Journal Article BMC Med · January 8, 2015 Prostate cancer (PCa) remains a leading cause of mortality in US men and the prevalence continues to rise world-wide especially in countries where men consume a 'Western-style' diet. Epidemiologic, preclinical and clinical studies suggest a potential role ... Full text Link to item Cite

Lifestyle and lower urinary tract symptoms: what is the correlation in men?

Journal Article Curr Opin Urol · January 2015 PURPOSE OF REVIEW: The primary purpose of this review is to provide an overview of the current evidence linking lifestyle factors and lower urinary tract symptoms (LUTS), and their relevance in men. An extensive literature search from January 2013 to Augus ... Full text Link to item Cite

Weight's up? Predictors of weight-related communication during primary care visits with overweight adolescents.

Journal Article Patient Educ Couns · September 2014 OBJECTIVE: Physicians' use of Motivational Interviewing (MI) techniques when discussing weight with adolescent patients is unknown. METHODS: We coded audio-recorded encounters between 49 primary care physicians and 180 overweight adolescent patients. Durin ... Full text Link to item Cite

A text messaging-assisted randomized lifestyle weight loss clinical trial among overweight adults in Beijing.

Journal Article Obesity (Silver Spring) · May 2014 OBJECTIVE: The impact of a text messaging-assisted lifestyle weight loss intervention on weight change among overweight adults in Beijing was examined. METHODS: It was a 6-month randomized two arm clinical trial. The control group received a brief advice s ... Full text Link to item Cite

The long-term effects of lifestyle change on blood pressure: One-year follow-up of the ENCORE study.

Journal Article Am J Hypertens · May 2014 BACKGROUND: There is a paucity of data describing the sustained benefits of lifestyle interventions on health behaviors and blood pressure (BP). METHODS: We examined the persistence of changes in health habits and BP in the ENCORE study, a trial in which 1 ... Full text Link to item Cite

Weight loss intervention for young adults using mobile technology: design and rationale of a randomized controlled trial - Cell Phone Intervention for You (CITY).

Journal Article Contemp Clin Trials · March 2014 BACKGROUND: The obesity epidemic has spread to young adults, leading to significant public health implications later in adulthood. Intervention in early adulthood may be an effective public health strategy for reducing the long-term health impact of the ep ... Full text Open Access Link to item Cite

Teen CHAT: Development and utilization of a web-based intervention to improve physician communication with adolescents about healthy weight.

Journal Article Patient Educ Couns · December 2013 OBJECTIVE: To describe the theoretical basis, use, and satisfaction with Teen CHAT, an online educational intervention designed to improve physician-adolescent communication about healthy weight. METHODS: Routine health maintenance encounters between pedia ... Full text Link to item Cite

The influence of a physician and patient intervention program on dietary intake.

Journal Article J Acad Nutr Diet · November 2013 BACKGROUND: Efficient dietary interventions for patients with hypertension in clinical settings are needed. OBJECTIVE: To assess the separate and combined influence of a physician intervention (MD-I) and a patient intervention (PT-I) on dietary intakes of ... Full text Link to item Cite

Nutrition, Lifestyle, and Hypertension

Journal Article · August 29, 2013 Full text Cite

Recruiting young adults into a weight loss trial: report of protocol development and recruitment results.

Journal Article Contemp Clin Trials · July 2013 Obesity has spread to all segments of the U.S. population. Young adults, aged 18-35 years, are rarely represented in clinical weight loss trials. We conducted a qualitative study to identify factors that may facilitate recruitment of young adults into a we ... Full text Open Access Link to item Cite

Can lifestyle modification improve neurocognition? Rationale and design of the ENLIGHTEN clinical trial.

Journal Article Contemp Clin Trials · January 2013 BACKGROUND: Risk factors for cardiovascular disease (CVD) not only increase the risk for clinical CVD events, but also are associated with a cascade of neurophysiologic and neuroanatomic changes that increase the risk of cognitive impairment and dementia. ... Full text Link to item Cite

Dietary intakes consistent with the DASH dietary pattern reduce blood pressure increase with age and risk for stroke in a Chinese population.

Journal Article Asia Pac J Clin Nutr · 2013 The Dietary Approaches to Stop Hypertension (DASH) diet has been proven to effectively lower blood pressure(BP), and associate with a lower cardiovascular disease and stroke risk in mainly non-Asians. Further, it is unclear if adhering to the DASH target n ... Link to item Cite

Determinants and consequences of adherence to the dietary approaches to stop hypertension diet in African-American and white adults with high blood pressure: results from the ENCORE trial.

Journal Article J Acad Nutr Diet · November 2012 BACKGROUND: Although the Dietary Approaches to Stop Hypertension (DASH) diet is an accepted nonpharmacologic treatment for hypertension, little is known about what patient characteristics affect dietary adherence and what level of adherence is needed to re ... Full text Link to item Cite

The Dietary Approaches to Stop Hypertension (DASH) eating pattern in special populations.

Journal Article Curr Hypertens Rep · October 2012 The Dietary Approaches to Stop Hypertension (DASH) trial showed that a diet rich in fruits, vegetables, low-fat dairy products with reduced total and saturated fat, cholesterol, and sugar-sweetened products effectively lowers blood pressure in individuals ... Full text Open Access Link to item Cite

Chapter 9: Lifestyle interventions for blood pressure control in children and adolescents

Chapter · June 25, 2012 Preface. Hypertension is a major risk factor for coronary heart disease, stroke, and premature death, and it affects approximately one-third of adults in the United States. Approximately, another one-third of the adults in the United States have .. ... Cite

Dietary saturated fat intake is negatively associated with weight maintenance among the PREMIER participants.

Journal Article Obesity (Silver Spring) · March 2012 Research finding on the composition of macronutrient intakes on body weight has not been consistent. Furthermore, little research has examined the impact of subcomponents of macronutrients such as saturated fat or plant protein on body weight. The purpose ... Full text Link to item Cite

Overview

Chapter · 2012 Cite

Nutrition, lifestyle factors, and blood pressure

Book · January 1, 2012 Even though enormous advancements have been made in identifying evidence-based lifestyle strategies for hypertension prevention and management, little progress has been made in implementing these proven strategies. Nutrition, Lifestyle Factors, and Blood P ... Cite

Overview

Book · January 1, 2012 Most researches on the association between nutrition, lifestyle factors, and blood pressure (BP) and relevant management plans have been conducted in adults with predetermined inclusion/exclusion criteria to minimize confounding of ndings from other physio ... Cite

Preface

Book · January 1, 2012 Cite

Macronutrients, dietary patterns, and blood pressure

Chapter · January 1, 2012 Dietary intake is closely related to blood pressure (BP) control. Besides sodium, many nutrients and minerals have been examined for their relationship with BP. In this chapter, we review the epidemiologic and clinical trial evidences for the potential imp ... Cite

Blood Pressure-Lowering Mechanisms of the DASH Dietary Pattern.

Journal Article J Nutr Metab · 2012 Potential blood pressure- (BP-) lowering mechanisms of the DASH dietary pattern were measured in 20 unmedicated hypertensive adults in a controlled feeding study. At screening, participants averaged 44.3 ± 7.8 years, BMI 33.9 ± 6.6 Kg/m(2), and BP 144.2 ± ... Full text Open Access Link to item Cite

Glycemic index and glycemic load are associated with some cardiovascular risk factors among the PREMIER study participants.

Journal Article Food Nutr Res · 2012 BACKGROUND: The clinical significance of glycemic index (GI) and glycemic load (GL) is inconclusive. OBJECTIVE: This study was conducted to examine the association of GI and GL with clinical cardiovascular disease (CVD) risk factors including body weight, ... Full text Link to item Cite

Dietary intakes associated with successful weight loss and maintenance during the Weight Loss Maintenance trial.

Journal Article J Am Diet Assoc · December 2011 BACKGROUND: Dietary components effective in weight maintenance efforts have not been adequately identified. OBJECTIVE: To determine the effects of changes in dietary consumption on weight loss and maintenance during the Weight Loss Maintenance clinical tri ... Full text Link to item Cite

Physician characteristics as predictors of blood pressure control in patients enrolled in the hypertension improvement project (HIP).

Journal Article J Clin Hypertens (Greenwich) · February 2011 The authors sought to examine the relationship between physician characteristics and patient blood pressure (BP) in participants enrolled in the Hypertension Improvement Project (HIP). In this cross-sectional study using baseline data of HIP participants, ... Full text Link to item Cite

Reducing consumption of sugar-sweetened beverages is associated with reduced blood pressure: a prospective study among United States adults.

Journal Article Circulation · June 8, 2010 BACKGROUND: Increased consumption of sugar-sweetened beverages (SSBs) has been associated with an elevated risk of obesity, metabolic syndrome, and type II diabetes mellitus. However, the effects of SSB consumption on blood pressure (BP) are uncertain. The ... Full text Link to item Cite

Effects of the dietary approaches to stop hypertension diet alone and in combination with exercise and caloric restriction on insulin sensitivity and lipids.

Journal Article Hypertension · May 2010 This study examined the effects of the Dietary Approaches to Stop Hypertension (DASH) diet on insulin sensitivity and lipids. In a randomized control trial, 144 overweight (body mass index: 25 to 40) men (n=47) and women (n=97) with high blood pressure (13 ... Full text Link to item Cite

Validation of a web-based dietary questionnaire designed for the DASH (dietary approaches to stop hypertension) diet: the DASH online questionnaire.

Journal Article Public Health Nutr · May 2010 OBJECTIVE: With the upsurge in online dietary modification programmes, online dietary assessment tools are needed to capture food intake. Although the DASH (Dietary Approaches to Stop Hypertension) diet is recommended by the US Department of Agriculture, t ... Full text Link to item Cite

Factors influencing dietary protein sources in the PREMIER trial population.

Journal Article J Am Diet Assoc · February 2010 Previous research suggests that protein intake, particularly plant protein, may benefit blood pressure control. However, very little has been published regarding protein sources in diets of US adults and factors influencing these choices. The purpose of th ... Full text Link to item Cite

Effects of the DASH diet alone and in combination with exercise and weight loss on blood pressure and cardiovascular biomarkers in men and women with high blood pressure: the ENCORE study.

Journal Article Arch Intern Med · January 25, 2010 BACKGROUND: Although the DASH (Dietary Approaches to Stop Hypertension) diet has been shown to lower blood pressure (BP) in short-term feeding studies, it has not been shown to lower BP among free-living individuals, nor has it been shown to alter cardiova ... Full text Link to item Cite

Hypertension improvement project: randomized trial of quality improvement for physicians and lifestyle modification for patients.

Journal Article Hypertension · December 2009 Despite widely publicized hypertension treatment guidelines for physicians and lifestyle recommendations for patients, blood pressure control rates remain low. In community-based primary care clinics, we performed a nested, 2 x 2 randomized, controlled tri ... Full text Link to item Cite

Reduction in consumption of sugar-sweetened beverages is associated with weight loss: the PREMIER trial.

Journal Article Am J Clin Nutr · May 2009 BACKGROUND: Consumption of liquid calories from beverages has increased in parallel with the obesity epidemic in the US population, but their causal relation remains unclear. OBJECTIVE: The objective of this study was to examine how changes in beverage con ... Full text Link to item Cite

Hypertension Improvement Project (HIP): study protocol and implementation challenges.

Journal Article Trials · February 26, 2009 BACKGROUND: Hypertension affects 29% of the adult U.S. population and is a leading cause of heart disease, stroke, and kidney failure. Despite numerous effective treatments, only 53% of people with hypertension are at goal blood pressure. The chronic care ... Full text Open Access Link to item Cite

The relationship between dietary protein intake and blood pressure: results from the PREMIER study.

Journal Article J Hum Hypertens · November 2008 Observational and clinical studies suggest that high protein intake, particularly protein from plant sources, might reduce blood pressure (BP). To examine the association of dietary protein with BP, we analysed data from PREMIER, an 18-month clinical trial ... Full text Link to item Cite

Weight loss during the intensive intervention phase of the weight-loss maintenance trial.

Journal Article Am J Prev Med · August 2008 BACKGROUND: To improve methods for long-term weight management, the Weight Loss Maintenance (WLM) trial, a four-center randomized trial, was conducted to compare alternative strategies for maintaining weight loss over a 30-month period. This paper describe ... Full text Link to item Cite

PREMIER--a trial of lifestyle interventions for blood pressure control: intervention design and rationale.

Journal Article Health Promot Pract · July 2008 Interventions encouraging adoption of healthy diets and increased physical activity are needed to achieve national goals for preventing and treating hypertension, cardiovascular disease, diabetes, and other chronic diseases. PREMIER was a multicenter clini ... Full text Link to item Cite

Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome.

Journal Article Hypertension · October 2007 Lifestyle modification can reduce blood pressure and lower cardiovascular risk. Established recommendations include weight loss, sodium reduction, and increased physical activity. PREMIER studied the effects of lifestyle interventions based on established ... Full text Link to item Cite

The PREMIER intervention helps participants follow the Dietary Approaches to Stop Hypertension dietary pattern and the current Dietary Reference Intakes recommendations.

Journal Article J Am Diet Assoc · September 2007 OBJECTIVE: To examine the influence of the PREMIER study lifestyle interventions on dietary intakes and adherence to the Dietary Approaches to Stop Hypertension (DASH) dietary pattern and the Dietary Reference Intakes (DRI). DESIGN: An 18-month multicenter ... Full text Link to item Cite

Acceptability of sodium-reduced research diets, including the Dietary Approaches To Stop Hypertension diet, among adults with prehypertension and stage 1 hypertension.

Journal Article J Am Diet Assoc · September 2007 OBJECTIVE: Examine the acceptability of sodium-reduced research diets. DESIGN: Randomized crossover trial of three sodium levels for 30 days each among participants randomly assigned to one of two dietary patterns. PARTICIPANTS/SETTING: Three hundred fifty ... Full text Link to item Cite

Reductions in dietary energy density are associated with weight loss in overweight and obese participants in the PREMIER trial.

Journal Article Am J Clin Nutr · May 2007 BACKGROUND: Dietary energy density (ED) reductions are associated with energy intake (EI) reductions. Little is known about influences on body weight (BW). OBJECTIVES: We examined the effects of behavioral interventions on ED values and explored how 6-mo E ... Full text Link to item Cite

Effects of individual components of multiple behavior changes: the PREMIER trial.

Journal Article Am J Health Behav · 2007 OBJECTIVES: To assess contributions of individual lifestyle changes on systolic blood pressure (SBP) changes. METHODS: We examined associations between lifestyle behavior changes and SBP after 6 and 18 months in 782 PREMIER trial participants. RESULTS: In ... Full text Link to item Cite

Effects of comprehensive lifestyle modification on diet, weight, physical fitness, and blood pressure control: 18-month results of a randomized trial.

Journal Article Ann Intern Med · April 4, 2006 BACKGROUND: The main 6-month results from the PREMIER trial showed that comprehensive behavioral intervention programs improve lifestyle behaviors and lower blood pressure. OBJECTIVE: To compare the 18-month effects of 2 multicomponent behavioral intervent ... Full text Link to item Cite

A dietary pattern that lowers oxidative stress increases antibodies to oxidized LDL: results from a randomized controlled feeding study.

Journal Article Atherosclerosis · November 2005 BACKGROUND: Oxidation of LDL (oxLDL) is thought to have an important role in early stages of atherogenesis. Antibody to oxLDL (Ab-oxLDL) has been proposed as a biomarker which might be directly associated with oxidative stress. Yet studies designed to test ... Full text Link to item Cite

One-year follow-up study of blood pressure and dietary patterns in dietary approaches to stop hypertension (DASH)-sodium participants.

Journal Article Am J Hypertens · December 2004 BACKGROUND: We conducted a 12-month follow-up study on participants in the Dietary Approaches to Stop Hypertension (DASH)-Sodium trial to determine the impact of the DASH diet and 150, 100, or 50 mmol/day of sodium after discontinuation of the feeding inte ... Full text Link to item Cite

The DASH diet for high blood pressure: from clinical trial to dinner table.

Journal Article Cleve Clin J Med · September 2004 Three recent studies show that a diet rich in fruits, vegetables, whole grains, and lowfat dairy products and low in fat, refined carbohydrates, and sodium can lower blood pressure either alone or in combination with other lifestyle changes. These studies ... Full text Link to item Cite

Effect of dietary sodium intake on blood lipids: results from the DASH-sodium trial.

Journal Article Hypertension · February 2004 We evaluated the effect on serum lipids of sodium intake in 2 diets. Participants were randomly assigned to a typical American control diet or the Dietary Approaches to Stop Hypertension (DASH) diet, each prepared with 3 levels of sodium (targeted at 50, 1 ... Full text Link to item Cite

The DASH diet and sodium reduction improve markers of bone turnover and calcium metabolism in adults.

Journal Article J Nutr · October 2003 Dietary strategies to prevent and treat osteoporosis focus on increased intake of calcium and vitamin D. Modification of whole dietary patterns and sodium reduction may also be effective. We examined the effects of two dietary patterns and three sodium lev ... Full text Link to item Cite

Premier: a clinical trial of comprehensive lifestyle modification for blood pressure control: rationale, design and baseline characteristics.

Journal Article Ann Epidemiol · July 2003 PURPOSE: To describe PREMIER, a randomized trial to determine the effects of multi-component lifestyle interventions on blood pressure (BP). METHODS: Participants with above optimal BP through stage 1 hypertension were randomized to: 1) a behavioral lifest ... Full text Link to item Cite

Food group sources of nutrients in the dietary patterns of the DASH-Sodium trial.

Journal Article J Am Diet Assoc · April 2003 The aim of this paper is to identify major food group sources of several essential nutrients in the two dietary patterns used in the DASH-Sodium trial: a control diet and the DASH dietary pattern. The DASH-Sodium trial was a multicenter, randomized, contro ... Full text Link to item Cite

Estimation of energy requirements in a controlled feeding trial.

Journal Article Am J Clin Nutr · March 2003 BACKGROUND: Estimating energy requirements is a frequent task in clinical studies. OBJECTIVE: We examined weight patterns of participants enrolled in a clinical trial and evaluated factors that may affect weight stabilization. The Harris-Benedict equation ... Full text Link to item Cite

Effects on blood lipids of a blood pressure-lowering diet: the Dietary Approaches to Stop Hypertension (DASH) Trial.

Journal Article Am J Clin Nutr · July 2001 BACKGROUND: Effects of diet on blood lipids are best known in white men, and effects of type of carbohydrate on triacylglycerol concentrations are not well defined. OBJECTIVE: Our goal was to determine the effects of diet on plasma lipids, focusing on subg ... Full text Link to item Cite

Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group.

Journal Article N Engl J Med · January 4, 2001 BACKGROUND: The effect of dietary composition on blood pressure is a subject of public health importance. We studied the effect of different levels of dietary sodium, in conjunction with the Dietary Approaches to Stop Hypertension (DASH) diet, which is ric ... Full text Link to item Cite

The effect of dietary patterns on blood pressure control in hypertensive patients: results from the Dietary Approaches to Stop Hypertension (DASH) trial.

Journal Article Am J Hypertens · September 2000 To determine the impact of dietary patterns on the control of hypertension we studied the subgroup of 133 participants with systolic blood pressure (BP) of 140 to 159 mm Hg and/or diastolic BP of 90 to 95 mm Hg enrolled in the Dietary Approaches to Stop Hy ... Full text Link to item Cite

Effect of dietary patterns on serum homocysteine: results of a randomized, controlled feeding study.

Journal Article Circulation · August 22, 2000 BACKGROUND: Elevated blood levels of homocysteine are associated with an increased risk of atherosclerotic cardiovascular disease. Although numerous studies have assessed the impact of vitamin supplements on homocysteine, the effect of dietary patterns on ... Full text Link to item Cite

The effects of dietary patterns on quality of life: a substudy of the Dietary Approaches to Stop Hypertension trial.

Journal Article J Am Diet Assoc · August 1999 Few studies have examined the effects of dietary changes, particularly modifications of whole dietary patterns, on quality of life. The Dietary Approaches to Stop Hypertension (DASH) trial compared the effects of 3 dietary patterns on blood pressure. In th ... Full text Link to item Cite

Dietary Approaches to Stop Hypertension: rationale, design, and methods. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 Epidemiologic studies across societies have shown consistent differences in blood pressure that appear to be related to diet. Vegetarian diets are consistently associated with reduced blood pressure in observational and interventional studies, but clinical ... Full text Link to item Cite

The DASH Diet, Sodium Intake and Blood Pressure Trial (DASH-sodium): rationale and design. DASH-Sodium Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 The DASH Diet, Sodium Intake and Blood Pressure Trial (DASH-Sodium) is a multicenter, randomized trial comparing the effects of 3 levels of sodium intake and 2 dietary patterns on blood pressure among adults with higher than optimal blood pressure or with ... Full text Link to item Cite

Comparison of 4 nutrient databases with chemical composition data from the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 Accuracy of computerized nutrient databases is an important consideration in selecting a nutrient analysis system. We project compared the nutrient content of daily menus calculated from 4 microcomputer programs to chemical analysis of menus analyzed for t ... Full text Link to item Cite

Dietary adherence in the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 Participants in controlled feeding studies must consume all study foods and abstain from all other foods. In outpatient studies in which adherence may be compromised by free-living conditions, promoting, documenting, and monitoring dietary adherence are ne ... Full text Link to item Cite

Descriptive characteristics of the dietary patterns used in the Dietary Approaches to Stop Hypertension Trial. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 The Dietary Approaches to Stop Hypertension trial was a randomized, multicenter, controlled feeding study to compare the effect on blood pressure of 3 dietary patterns: control, fruits and vegetables, and combination diets. The patterns differed in selecte ... Full text Link to item Cite

Dietary Approaches to Stop Hypertension: a summary of study results. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 The Dietary Approaches to Stop Hypertension multicenter trial examined the impact of dietary patterns on blood pressure in 459 adults with blood pressure < 160 mm Hg systolic and 80 to 95 mm Hg diastolic. After a 3-week run-in period on a control diet low ... Full text Link to item Cite

Pre-enrollment diets of Dietary Approaches to Stop Hypertension trial participants. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 A large body of evidence suggests that several nutrients are related to blood pressure. Less is known about the eating patterns of special populations, such as those at risk for hypertension, or how demographic factors affect the diets of these populations ... Full text Link to item Cite

The Linear Index Model for establishing nutrient goals in the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 Establishing target levels of nutrients in feeding studies presents a challenge to dietitians. Although researchers studying energy-containing nutrients, such as protein and fat, commonly establish target levels according to body weight or as a percentage ... Full text Link to item Cite

Validation of diet composition for the Dietary Approaches to Stop Hypertension trial. DASH Collaborative Research Group.

Journal Article J Am Diet Assoc · August 1999 The Dietary Approaches to Stop Hypertension trial involved 4 clinical sites at which 459 participants (in 5 cohorts) were fed 3 dietary patterns over 11 weeks per cohort. The 3 patterns were a control diet, a fruits and vegetables diet, and a combination d ... Full text Link to item Cite

A dietary approach to prevent hypertension: A review of the dietary approaches to stop hypertension (DASH) study

Journal Article Clinical Cardiology · July 14, 1999 Background: Populations eating mainly vegetarian diets have lower blood pressure levels than those eating omnivorous diets. Epidemiologic findings suggest that eating fruits and vegetables lowers blood pressure. Hypothesis: Two hypotheses were tested: (1) ... Cite

A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group.

Journal Article N Engl J Med · April 17, 1997 BACKGROUND: It is known that obesity, sodium intake, and alcohol consumption factors influence blood pressure. In this clinical trial, Dietary Approaches to Stop Hypertension, we assessed the effects of dietary patterns on blood pressure. METHODS: We enrol ... Full text Link to item Cite

Metabolic and behavioral effects of a high-sucrose diet during weight loss.

Journal Article Am J Clin Nutr · April 1997 In response to evidence linking obesity and high amounts of dietary fat, the food industry has developed numerous reduced-fat and nonfat food items. These items frequently derive a relatively large percentage of their energy from sugars and the effect of t ... Full text Link to item Cite

Comparable diet recall accuracy between dieters and non-dieters participating in feeding studies

Conference FASEB Journal · December 1, 1996 Validation of diet assessment methods has been limited by the lack of a true gold standard. Direct observation has been considered as one of the nearest gold standards available, and has been employed over short time periods only (1 to 5 days). Since diete ... Cite

Rationale and design of the Dietary Approaches to Stop Hypertension trial (DASH). A multicenter controlled-feeding study of dietary patterns to lower blood pressure.

Journal Article Ann Epidemiol · March 1995 Epidemiologic studies have found that dietary patterns characterized by high intakes of certain minerals and fiber are associated with low blood pressure. Dietary Approaches to Stop Hypertension (DASH) is a multicenter, randomized, controlled-feeding trial ... Full text Link to item Cite

Community dwelling elderly are appropriate subjects for intensive dietary choice restriction studies.

Journal Article J Nutr Elder · 1995 There is a traditional belief that the elderly have difficulty coping with dietary change, and therefore have a diminished likelihood of successfully responding to nutritional interventions or restrictions. Using a controlled mild zinc-deficiency feeding s ... Full text Link to item Cite

Marginal zinc deficiency in older adults: responsiveness of zinc status indicators.

Journal Article J Am Coll Nutr · October 1994 OBJECTIVE: Suspicions that mild zinc deficiency is common among the elderly cannot be confirmed or refuted because definitive indicators of zinc status are lacking. The goal of this study was to document the clinical responsiveness of parameters of zinc st ... Full text Link to item Cite

RELATIONSHIPS AMONG IRON INTAKE, MEAT CONSUMPTION, AND IRON (FE) STORES IN AN OLDER ADULT-POPULATION

Journal Article JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION · October 1, 1994 Link to item Cite

Plasma uptake of manganese as affected by oral loads of manganese, calcium, milk, phosphorus, copper, and zinc.

Journal Article J Am Coll Nutr · February 1991 Six adult subjects were administered a series of manganese (Mn) tolerance tests to investigate the influence of various minerals on Mn plasma uptake. Oral loads given to all six subjects included 40 mg manganese alone, or with 800 mg calcium (Ca) as either ... Full text Link to item Cite

Metabolic balance of manganese in young men consuming diets containing five levels of dietary manganese.

Journal Article J Nutr · June 1988 Five healthy men, ages 19-20, were fed a diet for 105 d to measure manganese balance during consumption of conventional foods. The study was divided into five periods of 21, 21, 38, 11 and 14 d, in which the daily dietary intakes of manganese (Mn) were 2.8 ... Full text Link to item Cite