Journal ArticleJournal of Choice Modelling · December 1, 2024
Use of preference information to infer risk tolerance has increased in recent years as a way to inform benefit-risk evaluations in regulatory and medical decision making. However, a framework for the measurement of tolerance for multiple uncertain outcomes ...
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Journal ArticleCirc Cardiovasc Qual Outcomes · November 21, 2024
BACKGROUND: Regulatory approval of the first dual-chamber leadless pacemaker system provides patients an alternative to conventional transvenous pacemakers. The study objective was to quantify the preferences of patients for pacemaker features. METHODS: Pa ...
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Journal ArticleMed Decis Making · August 2024
INTRODUCTION: Despite decades of research on risk-communication approaches, questions remain about the optimal methods for conveying risks for different outcomes across multiple time points, which can be necessary in applications such as discrete choice ex ...
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Journal ArticlePatient · July 24, 2024
This paper provides an introduction to statistical analysis of choice data using example data from a simple discrete-choice experiment (DCE). It describes the layout of the analysis dataset, types of variables contained in the dataset, and how to identify ...
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Journal ArticleJournal of Choice Modelling · June 1, 2024
Pooling data from different subgroups offers advantages of shrinking standard errors and simplifying characterization of the data structure. The ability to pool data also facilitates meta-analysis to evaluate consensus among multiple studies and to inform ...
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Journal ArticleMDM Policy Pract · 2024
UNLABELLED: Introduction. Serogroup B (MenB) is the leading cause of invasive meningococcal disease among adolescents and young adults in the United States. The US Advisory Committee on Immunization Practices (ACIP) recommends MenB vaccination based on sha ...
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Journal ArticlePharmacoeconomics · August 2023
While the quality-adjusted life-year construct has advantages of simplicity and consistency, simplicity requires strong assumptions. In particular, standard assumptions result in health-state utility functions that are unrealistically linear and separable ...
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Journal ArticlePatient · March 2023
BACKGROUND: Because immunizing large numbers of healthy people could be required to reduce a relatively small number of infections, disease incidence has a large impact on cost effectiveness, even if the infection is associated with very serious health out ...
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Journal ArticleMed Decis Making · February 2023
BACKGROUND: While clinical practice guidelines underscore the need to incorporate patient preferences in clinical decision making, incorporating meaningful assessment of patient preferences in clinical encounters is challenging. Structured approaches that ...
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Chapter · December 13, 2022
This paper reports the first effort to use data to evaluate how new information, acquired through exogenous health shocks, affects people's longevity expectations. We find that smokers react differently to health shocks than do those who quit smoking or ne ...
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Chapter · December 13, 2022
This article provides the first controlled evaluation of how different information materials explaining the risks from radon influenced people's perceptions of these risks. Using a panel study, it was possible to observe how stated risk perceptions respond ...
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Chapter · December 13, 2022
This article reports the results of an evaluation of the effectiveness of different types of information materials in communicating the risk from exposure to radon, a naturally occurring indoor air pollutant. The study involved a panel of 2300 homeowners w ...
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Chapter · December 13, 2022
A specialized survey of Maine households' responses to information about the risks associated with radon con centrations in their homes and water supplies was used to evaluate how they form risk perceptions. The findings support a modified form of a Bayesi ...
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Journal ArticlePatient · May 2022
BACKGROUND: Women with inflammatory bowel disease (IBD) face difficult decisions regarding treatment during pregnancy: while the majority of IBD medications are safe, there is substantial societal pressure to avoid exposures during pregnancy. However, disc ...
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Journal ArticleJ Pain Symptom Manage · April 2022
CONTEXT: Health systems should aim to deliver on what matters most to patients. With respect to end of life (EOL) care, knowledge on patient preferences for care is currently lacking. OBJECTIVES: To quantify preference weights for key EOL care indicators. ...
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Journal ArticleEpilepsy Behav · February 2022
OBJECTIVE: To determine patient acceptability of benefit-risk trade-offs in selecting treatment options for drug-resistant mesial temporal lobe epilepsy, including open brain surgery, laser ablation (laser interstitial thermal therapy [LITT]), and continue ...
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Journal ArticleCirc Heart Fail · January 2022
BACKGROUND: Regulatory and clinical decisions involving health technologies require judgements about relative importance of their expected benefits and risks. We sought to quantify heart-failure patients' acceptance of therapeutic risks in exchange for imp ...
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Journal ArticleHealth Econ · November 2021
Violations of the assumptions of complete information [CI] and independence of irrelevant alternatives (IIA) in discrete-choice experiment (DCE) data imply sensitivity of preference estimates to the decision context and the alternatives evaluated. There is ...
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Journal ArticleValue Health · October 2021
BACKGROUND: 'Hope' is a construct in patient-centered value frameworks, but few studies have attempted to measure the value of hope separately from treatment-related gains in quality of life and survival to support its application in economic evaluation. O ...
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Journal ArticleJ Allergy Clin Immunol Pract · September 2021
BACKGROUND: Recently developed peanut desensitization treatment reduces the incidence of allergic reactions, the anxiety associated with the risk of accidental exposure, and the burden of precautionary behavior. Eliciting parent preferences for tradeoffs i ...
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Journal ArticleMilbank Q · September 2021
UNLABELLED: Policy Points  Public funding for mental health programs must compete with other funding priorities in limited state budgets.  Valuing state-funded mental health programs in a policy-relevant context requires consideration of how much benefit f ...
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Journal ArticleGynecol Oncol · August 2021
OBJECTIVE: To assess preferences of women with ovarian cancer regarding features of available anti-cancer regimens for platinum-resistant, biomarker-positive disease, with an emphasis on oral PARP inhibitor and standard intravenous (IV) chemotherapy regime ...
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Journal ArticleMed Decis Making · February 2021
OBJECTIVES: To test the convergent validity of simple and more complex study designs in a discrete-choice experiment (DCE) of multiple sclerosis (MS) treatment preferences. METHODS: Five hundred US adults with MS completed an online DCE survey. Respondents ...
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Journal ArticleJ Bone Joint Surg Am · December 2, 2020
BACKGROUND: Total knee arthroplasty (TKA) is a common treatment for end-stage knee osteoarthritis but is associated with increased complication rates compared with unicompartmental knee arthroplasty (UKA). UKA offers better functional outcomes but is assoc ...
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Journal ArticleValue Health · November 2020
OBJECTIVE: To conduct a discrete-choice experiment to quantify Americans' acceptance of severe acute respiratory syndrome coronavirus 2 infection risks for earlier lifting of social-distancing restrictions and diminishing the pandemic's economic impact. ME ...
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Journal ArticleNeurology Psychiatry and Brain Research · September 1, 2020
Background: Novel ketamine-based pharmacotherapies can reduce depressive symptoms among patients with treatment-resistant depression (TRD), but associated short-term symptoms and potential adverse events raise complex benefit-risk questions. Methods: A web ...
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Journal ArticleValue Health · April 2020
The International Society for Pharmacoeconomics and Outcomes Research (ISPOR)'s "Good Practices Task Force" reports are highly cited, multistakeholder perspective expert guidance reports that reflect international standards for health economics and outcome ...
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Journal ArticleGynecol Oncol · March 2020
OBJECTIVE: To measure preferences of women with ovarian cancer regarding risks, side effects, costs and benefits afforded by maintenance therapy (MT) with a poly ADP ribose polymerase (PARP) inhibitor. METHODS: A discrete-choice experiment elicited prefere ...
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Journal ArticleClin Gastroenterol Hepatol · February 2020
BACKGROUND & AIMS: Patients with Crohn's disease (CD) must make decisions about their treatment. We aimed to quantify patients' preferences for different treatment outcomes and adverse events. We also evaluated the effects of latent class heterogeneity on ...
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Journal ArticleCirc Cardiovasc Interv · December 2019
BACKGROUND: The Food and Drug Administration's Center for Drugs and Radiological Health issued Guidance in 2016 on generating patient preference information to aid evaluation of medical devices. Consistent with this guidance, we aimed to provide quantitati ...
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Journal ArticleValue Health · September 2019
BACKGROUND: The objective of the study was to understand respondents' willingness to accept hypothetical treatment-related risks in return for the benefit of additional time with normal memory from potential Alzheimer's disease interception therapies. METH ...
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Journal ArticleValue Health · June 2019
BACKGROUND: The popularity of quality-adjusted life years (QALYs) has been resistant to concerns about validity and reliability. Utility-theoretic outcome equivalents are widely used in other areas of applied economics. Equivalence values can be derived fo ...
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ConferenceJournal of Clinical Oncology · May 20, 2019
5558 Background: Maintenance therapy with PARP inhibitors has become prevalent in treating ovarian cancer. However, the preferences of women with ovarian cancer regarding the risks, side effects and benefits afforded by maintenan ...
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Journal ArticleInflamm Bowel Dis · April 11, 2019
BACKGROUND: Corticosteroids (CS) and anti-TNF drugs are used to treat Crohn's disease (CD). In this study, we assessed the net health benefit of initiating anti-TNF therapy relative to additional CS use in CD using a novel combination of a retrospective co ...
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Journal ArticleValue Health · February 2019
OBJECTIVES: To develop a tool for testing internal validity of discrete choice experiment (DCE) data, deploy the program, and collect summary test results from a sample of active health researchers to demonstrate the practical utility of the tool in a wide ...
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Journal ArticleSports Med · August 2018
BACKGROUND: The Goldman dilemma presented athletes with a Faustian bargain that guaranteed winning an Olympic gold medal in their sport but resulted in certain death 5Â years later. Athletes' responses to Goldman's bargain were reported from 1982 to 1995. S ...
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Journal ArticleTher Innov Regul Sci · July 2018
BACKGROUND: Formal incorporation of patients' perspectives is becoming increasingly important in medical product development and decision making. This article shares practical advice regarding how patient advocacy organizations, the pharmaceutical industry ...
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Journal ArticleJ Dermatolog Treat · December 2017
PURPOSE: The purpose of this study was to provide quantitative evidence of patients' tolerance for therapeutic risks associated with psoriasis treatments that could offer psoriasis improvements beyond the PASI 75 benchmark. MATERIALS AND METHODS: We used a ...
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Journal ArticleValue Health · April 2017
BACKGROUND: As more studies report on patient preferences for diabetes treatment, identifying diabetes outcomes other than glycated hemoglobin (HbA1c) to describe effectiveness is warranted to understand patient-relevant, benefit-risk tradeoffs. OBJECTIVE: ...
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Journal ArticleBr J Dermatol · March 2017
BACKGROUND: Plaque psoriasis can have a significant negative effect on patients' quality of life, and treatments can result in serious toxicities. Although there have been several studies of patients' and physicians' relative preferences for the benefits a ...
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Journal ArticleValue Health · January 2017
We examine key study design challenges of using stated-preference methods to estimate the value of whole-genome sequencing (WGS) as a specific example of genomic testing. Assessing the value of WGS is complex because WGS provides multiple findings, some of ...
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Chapter · January 1, 2017
In 2006, a preference study of patients risk tolerance was submitted to the US Food and Drug Administration (FDA) Tysabri Advisory Committee as part of the drugs reapproval application. This submission marked the first time such evidence was included in su ...
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Journal ArticleHealth Econ Rev · December 2016
Best-worst scaling (BWS), also known as maximum-difference scaling, is a multiattribute approach to measuring preferences. BWS aims at the analysis of preferences regarding a set of attributes, their levels or alternatives. It is a stated-preference method ...
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Journal ArticleHealth Econ Rev · December 2016
For optimal solutions in health care, decision makers inevitably must evaluate trade-offs, which call for multi-attribute valuation methods. Researchers have proposed using best-worst scaling (BWS) methods which seek to extract information from respondents ...
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Journal ArticleGenet Med · December 2016
PURPOSE: Whole-genome sequencing (WGS) can be used as a powerful diagnostic tool as well as for screening, but it may lead to anxiety, unnecessary testing, and overtreatment. Current guidelines suggest reporting clinically actionable secondary findings whe ...
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Journal ArticleTher Innov Regul Sci · September 2016
Benefit-risk assessment is the foundation for decision making throughout the life cycle of medical products. Because patients are the beneficiaries of the efficacy of medical treatments and also bear their possible risks, their perspectives and judgments a ...
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Journal ArticleJournal of Choice Modelling · September 1, 2016
This study demonstrates how experimental survey methods can be used to assess preferences for budget-constrained combinations of public and publicly provided goods and services. The study shows how to calculate welfare changes based on preferences for incr ...
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Journal ArticleAppl Health Econ Health Policy · June 2016
Stated-preference methods increasingly are used to quantify preferences in health economics, health technology assessment, benefit-risk analysis and health services research. The objective of stated-preference studies is to acquire information about trade- ...
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Journal ArticlePatient · February 2016
OBJECTIVE: Our objective was to quantify preferences and stated adherence for inhaled antibiotic treatments in cystic fibrosis (CF). METHODS: Adult CF patients and parents of pediatric patients in the US who were members of the Cystic Fibrosis Foundation a ...
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Journal ArticleJ Dev Behav Pediatr · January 2016
OBJECTIVE: Fragile X syndrome (FXS) is the most common inherited form of intellectual disability. The objective of this study was to determine the relative importance that caregivers place on improving different phenotypic traits observed in males with FXS ...
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Journal ArticleValue Health · January 2016
OBJECTIVE: The diagnosis of Alzheimer's disease (AD) remains difficult. Lack of diagnostic certainty or possible distress related to a positive result from diagnostic testing could limit the application of new testing technologies. The objective of this pa ...
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Journal ArticleValue Health · 2016
Demands for greater transparency in US regulatory assessments of benefits and risks, together with growing interest in engaging patients in Food and Drug Administration regulatory decision making, have resulted in several recent regulatory developments. Al ...
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Journal ArticleAm J Gastroenterol · December 2015
OBJECTIVES: Biomarkers, endoscopy and imaging tests can identify patients at increased risk for early recurrence of symptomatic inflammatory bowel disease (IBD). However, patients may be unwilling to accept additional medical therapy risks related to thera ...
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Journal ArticlePsychiatr Serv · July 2015
OBJECTIVE: The objective of this study was to quantify patients' preferences related to benefits and risks of antipsychotic treatments for schizophrenia and to assess the relative importance of treatment attributes and adherence. METHODS: Treatment-related ...
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Journal ArticleJournal of Choice Modelling · June 1, 2015
Expected-utility theory is embraced by some researchers because of its theoretical and empirical tractability, although empirical testing has exposed systematic behavioral inconsistencies that violate the axiom of independence in the theory. In particular, ...
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Journal ArticleJournal of Choice Modelling · June 1, 2015
Background Best-practice guidelines for stated-preference methods suggest there is a limit to the number of attributes respondents can reliably evaluate. This study explores a cost-effective solution to combining elicitation formats from a single study to ...
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Journal ArticleJ Dermatolog Treat · 2015
BACKGROUND: Previous studies suggest that efficacy is more important than side-effect risks to psoriasis patients. However, those studies did not consider potentially fatal risks of biologic treatments. OBJECTIVE: To quantify the risks patients are willing ...
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Journal ArticleValue Health · January 2015
BACKGROUND: Meningococcal disease is rare but can cause death or disabilities. Although the Advisory Committee on Immunization Practices has recommended meningococcal vaccination for at-risk children aged 9 through 23 months, it has not endorsed universal ...
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Journal ArticleValue Health · December 2014
BACKGROUND: The value of the information that genetic testing services provide can be questioned for insurance-based health systems. The results of genetic tests oftentimes may not lead to well-defined clinical interventions; however, Lynch syndrome, a gen ...
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Journal ArticleMonthly Notices of the Royal Astronomical Society · September 5, 2014
The standard cosmological model, Λ cold dark matter (ΛCDM), provides an excellent fit to cosmic microwave background (CMB) data. However, the model has well-known problems. For example, the cosmological constant, Λ, is fine-tuned to 1 part in 10100 and the ...
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Journal ArticlePsychiatr Serv · September 1, 2014
OBJECTIVE: The objectives were to quantify psychiatrists' judgments of the benefits and risks of antipsychotic treatments of patients with schizophrenia and to evaluate how patient adherence history affects these judgments. METHODS: Weights assigned by res ...
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Journal ArticleQual Life Res · August 2014
PURPOSE: To estimate the relative importance that Alzheimer's disease (AD) caregivers in the United States and Germany place on preserving patients' ability to perform activities of daily living. METHODS: US and German residents providing care for a person ...
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Journal ArticleInflamm Bowel Dis · January 2014
BACKGROUND: Therapy options for mesalamine-refractory ulcerative colitis (UC) include immunosuppressive medications or surgery. Chronic immunosuppressive therapy increases risks of infection and cancer, whereas surgery produces a permanent change in bowel ...
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Journal ArticleAdv Health Econ Health Serv Res · 2014
PURPOSE: To measure adolescent girls' preferences over features of human papillomavirus (HPV) vaccines in order to provide quantitative estimates of the perceived benefits of vaccination and potential vaccine uptake. DESIGN/METHODOLOGY/APPROACH: A discrete ...
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Journal ArticleDiabetes Ther · December 2013
INTRODUCTION: The purpose of this study was to quantify United States (US) and United Kingdom (UK) physicians' preferences for attributes of type 2 diabetes treatments. METHODS: Samples of general practitioners (GPs) and endocrinologists in the US (n = 204 ...
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Journal ArticleDiabetes Metab · October 2013
AIMS: The aim of the study was to quantify patient preferences for outcomes associated with oral antidiabetic medications (OAMs) in Sweden and Germany through a discrete-choice experiment. METHODS: Adults taking OAMs who had a self-reported physician's dia ...
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Journal ArticleAppl Health Econ Health Policy · August 2013
Decisions regarding the development, regulation, sale, and utilization of pharmaceutical and medical interventions require an evaluation of the balance between benefits and risks. Such evaluations are subject to two fundamental challenges-measuring the cli ...
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Journal ArticleApplied Economics · June 1, 2013
Health and environmental economists have been employing Stated-Preference (SP) methods such as conjoint analysis or contingent valuation to estimate the monetary value of public health interventions and environmental goods and services. However, the qualit ...
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Journal ArticleOsteoarthritis Cartilage · February 2013
OBJECTIVE: To assess patient preferences for treatment-related benefits and risks associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in the management of osteoarthritis (OA). DESIGN: Using a chronic-illness panel in the United Kingdom ...
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Journal ArticleValue Health · 2013
Stated-preference methods are a class of evaluation techniques for studying the preferences of patients and other stakeholders. While these methods span a variety of techniques, conjoint-analysis methods-and particularly discrete-choice experiments (DCEs)- ...
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Journal ArticlePatient · 2013
Inflammatory bowel disease (IBD), consisting of both Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory conditions of the intestinal tract. As there is no cure for either CD or UC, patients with these conditions face numerous treatm ...
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Journal ArticleHeadache · 2013
OBJECTIVE: The impact of migraines on patients is commonly divided between the level of impairment associated with headache symptoms (headache phase) and the quality-of-life effects immediately following the headache (post-headache phase). Evaluations of m ...
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Journal ArticleJ Rheumatol · May 2012
OBJECTIVE: To quantify the relative importance that UK physicians attach to the benefits and risks of current drugs when making treatment decisions for patients with osteoarthritis (OA). METHODS: Physicians treating at least 10 patients with OA per month c ...
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Journal ArticleEur J Gastroenterol Hepatol · April 2012
OBJECTIVE: To quantify physicians' preferences among possible outcomes associated with chronic hepatitis B treatments and to determine which outcomes are most important to physicians in making treatment decisions. METHODS: Physicians in five countries who ...
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Journal ArticleVaccine · October 19, 2011
Rotavirus is the most common cause of severe gastroenteritis in infants and young children worldwide. Health-state utility measures used in economic evaluations of rotavirus vaccines do not reflect differences between mild and severe symptoms of rotavirus ...
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Journal ArticleValue Health · June 2011
BACKGROUND: The application of conjoint analysis (including discrete-choice experiments and other multiattribute stated-preference methods) in health has increased rapidly over the past decade. A wider acceptance of these methods is limited by an absence o ...
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Journal ArticleHealth Econ · March 2011
Willingness-to-pay (WTP) estimates derived from discrete-choice experiments (DCEs) generally assume that the marginal utility of income is constant. This assumption is consistent with theoretical expectations when costs are a small fraction of total income ...
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Journal ArticleMed Decis Making · 2011
This study applies conjoint analysis to estimate health-related benefit-risk tradeoffs in a non-expected-utility framework. We demonstrate how this method can be used to test for and estimate nonlinear weighting of adverse-event probabilities and we explor ...
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Chapter · January 1, 2011
In managing Crohn's disease (CD), gastroenterologists increasingly are adopting earlier, more aggressive strategies in the hope of altering the course of the disease. Biologic therapies such as the inhibitors of Tumor Necrosis Factor-alpha (TNF-), inflixim ...
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Journal ArticlePatient · December 1, 2010
BACKGROUND: : Many patient-reported outcomes (PRO) instruments are scored by averaging or summing Likert category values over all items or domains of the elicitation instrument, yielding domain-specific scores or a total score for the entire instrument. OB ...
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Journal ArticlePatient · December 1, 2010
Despite the increased popularity of conjoint analysis in health outcomes research, little is known about what specific methods are being used for the design and reporting of these studies. This variation in method type and reporting quality sometimes makes ...
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Journal ArticleJ Manag Care Pharm · October 2010
BACKGROUND: Crohn's disease is a serious and debilitating gastrointestinal disorder with a high, unmet need for new treatments. Biologic agents have the potential to alter the natural course of Crohn's disease but present known risks of potential serious a ...
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Journal ArticleQual Life Res · June 2010
PURPOSE: Our objective was to estimate preference-based weights for the IWQOL-Lite that reflect the relative importance overweight and obese people place on the domains included in the instrument. METHODS: US residents, 18 years of age or older, who are ov ...
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Journal ArticleAnn Pharmacother · March 2010
BACKGROUND: Idiopathic thrombocytopenic purpura (ITP) primarily is a disorder of adults characterized by autoantibody-induced platelet destruction and reduced platelet production, leading to a low peripheral blood platelet count. The long-term management o ...
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Journal ArticleVaccine · February 17, 2010
A choice-format, conjoint-analysis survey was developed and fielded to estimate how features of human papillomavirus (HPV) vaccines affect mothers' perceived benefit and stated vaccine uptake for daughters. Data were collected from a national sample of 307 ...
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Journal ArticleHealth Econ · January 2010
Responses of inattentive or inconsistent subjects in stated-choice (SC) surveys can lead to imprecise or biased estimates. Several SC studies have investigated inconsistency and most of these studies dropped subjects who were inconsistent. However, none of ...
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Journal ArticleValue Health · 2010
BACKGROUND: The Food and Drug Administration, currently, is exploring quantitative benefit-risk methods to support regulatory decision-making. A scientifically valid method for assessing patients' benefit-risk trade-off preferences is needed to compare ris ...
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Journal ArticleSoc Sci Med · January 2010
Researchers usually employ orthogonal arrays or D-optimal designs with little or no attribute overlap in stated-choice surveys. The challenge is to balance statistical efficiency and respondent burden to minimize the overall error in the survey responses. ...
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Journal ArticleValue Health · 2010
OBJECTIVE: There is consensus that a more transparent, explicit, and rigorous approach to benefit-risk evaluation is required. The objective of this study is to evaluate the incremental net benefit (INB) framework for undertaking quantitative benefit-risk ...
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Journal ArticleHealth Econ · December 2009
BACKGROUND: Patient preferences can affect colorectal cancer (CRC) screening test use. We compared utility-based preferences for alternative CRC screening tests from a stated-preference discrete-choice survey of the general population and physicians in Can ...
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Journal ArticleJ Health Econ · July 2009
Subjects with rheumatoid arthritis (RA) enrolled in an online panel were asked to evaluate pairs of treatment alternatives with different attributes. Half of the sample saw a cheap-talk text. Preference parameters were estimated using random-parameters log ...
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Journal ArticleJ Neurol · April 2009
OBJECTIVE: The aim of this study is to estimate the willingness of multiple sclerosis (MS) patients to accept life-threatening adverse event risks in exchange for improvements in their MS related health outcomes. METHODS: MS patients completed a survey que ...
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Journal ArticleDiabet Med · April 2009
AIMS: Medication non-adherence is particularly common in patients with Type 2 diabetes. We constructed a discrete-choice experiment to examine the relative importance of oral glucose-lowering medication features and to estimate the likely effect of effecti ...
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Journal ArticleAm J Prev Med · March 2009
BACKGROUND: Physical inactivity is a major driver of costly health problems, especially in older adults. Structured walking programs are one approach for increasing physical activity, although there is little information about how the characteristics of th ...
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Journal ArticleAlzheimer Dis Assoc Disord · 2009
Alzheimer disease (AD) is a progressive, ultimately fatal neurodegenerative illness affecting millions of patients, families, and caregivers. Effective disease-modifying therapies for AD are desperately needed, but none currently exist on the market. Thus, ...
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Journal ArticleAllergy Asthma Proc · 2009
The Onset-of-Effect Questionnaire (OEQ) is a self-administered instrument used to assess patient perception of how quickly asthma maintenance medications begin to work. This study was designed to quantify the relative importance that patients using combina ...
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Journal ArticleValue Health · 2009
OBJECTIVE: Conventional standard gamble and time trade-off methods may be inappropriate for eliciting preferences for some health states because both require subjects to make trade-offs between a morbid health state and death. Thus, the objective of this s ...
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Journal ArticleAIDS Patient Care STDS · January 2009
While African Americans in the United States are disproportionately affected by HIV, they are less likely to take antiretroviral therapies. Different first-line antiretroviral therapies are associated with short-term and long-term adverse event (AE) risks. ...
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Journal ArticleRisk Anal · January 2009
Understanding patient-specific differences in risk tolerance for new treatments that offer improved efficacy can assist in making difficult regulatory and clinical decisions for new treatments that offer both the potential for greater effectiveness in reli ...
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Journal ArticlePatient · December 1, 2008
Stated-choice (SC) surveys, such as conjoint analysis, present some interesting problems for researchers that are not addressed in the traditional survey-development literature. While the constraints imposed by preference theory, the experimental design of ...
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Journal ArticleBlood · November 16, 2008
AbstractOBJECTIVE: To quantify the willingness of patients with chronic idiopathic thrombocytopenic purpura (ITP) to trade off different attributes of ITP treatments, including efficacy, safety, and mode of ...
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Journal ArticleLand Economics · January 1, 2008
We examine snowmobile use conflict in Yellowstone National Park to assess the effect of different winter management policies on heterogeneous visitors' welfare. Using a stated preference choice experiment we quantify welfare changes for snowmobile riders a ...
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Journal ArticleJ Womens Health (Larchmt) · September 2007
BACKGROUND: Evidence that long-term hormone therapy (HT) may increase the risk of serious adverse events led to a sharp reduction in all HT use, including short-term use for vasomotor symptom relief. We estimated women's willingness to accept adverse event ...
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Journal ArticleGastroenterology · September 2007
BACKGROUND & AIMS: Regulatory assessments of drug risks do not routinely consider patient preferences, despite evidence that some patients are willing to accept increased side-effect risk in exchange for therapeutic benefits. The aim of this study is to es ...
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Journal ArticleMed Care · June 2007
BACKGROUND: Medication nonadherence is high among patients with bipolar disorder, and may lead to poor clinical outcomes, decreased quality of life, and increased resource utilization. OBJECTIVE: To investigate the factors associated with nonadherence and ...
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Journal ArticleEconomic Inquiry · January 1, 2007
We examine the effect of giving respondents time to think about their stated choices (SC) in a survey of cholera and typhoid vaccine preferences in Hue, Vietnam. Because neither vaccine is widely available in Vietnam, we used the SC approach (a stated pref ...
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Journal ArticleValue Health · 2007
OBJECTIVE: Colorectal cancer (CRC) screening uptake remains poor. Until we understand patient motivation and preferences for undertaking screening, it is unlikely the uptake will be optimal. Our objective is to examine patient preferences for CRC screening ...
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Journal ArticleResource and Energy Economics · August 1, 2006
Individuals can reduce their exposure to air pollution by reducing the amount of time they spend outdoors. Reducing outdoor time is an example of an averting behavior that should be measured as part of willingness to pay (WTP) for improvements in air quali ...
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Journal ArticleDiabetes Care · June 2006
OBJECTIVE: The purpose of this study was to estimate how much at-risk individuals are willing to pay for type 2 diabetes primary prevention programs. RESEARCH DESIGN AND METHODS: An Internet-based, choice-format conjoint survey was presented to individuals ...
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Journal ArticleEnvironmental and Resource Economics · May 1, 2006
There are very few studies that quantify the interactions and tradeoffs between statistical and cognitive efficiency in designing stated-choice studies. While a conceptual framework for evaluating cognitive strategies would be desirable, Hensher adopts a s ...
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Journal ArticleQual Life Res · March 2006
OBJECTIVE: To compare a linear scoring rule with the subjective importance of different domain and symptom levels of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30) among patients undergoing ...
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Journal ArticleQual Life Res · March 2006
OBJECTIVES: It is postulated that patients with different cancer diagnoses, stages of disease and treatments will exhibit different individual preferences for health-related quality-of-life (HRQOL) functional domains and symptoms. METHODS: A stated-prefere ...
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Journal ArticleValue Health · 2006
OBJECTIVES: The principal aim of this study was to illustrate applying discrete-choice methods for eliciting preferences for technology adoption criteria, including threshold values for cost-effectiveness ratios. A secondary objective was to compare the cr ...
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Journal ArticleMarketing Letters · December 1, 2005
From a practical perspective, (arguably) most consumer decisions are not made in isolation of the households in which consumers are inserted, yet we commonly treat them econometrically as if they were. The purpose of this workshop was to take some initial ...
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Journal ArticleHealth Econ · December 2003
In conjoint analysis (CA) studies, choosing between scenarios with multiple health attributes may be demanding for respondents. This study examined whether simplifying the choice task in CA designs, by using a design with more overlap of attribute levels, ...
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Journal ArticleEnviron Health · December 18, 2002
BACKGROUND: Few assessments of the costs and benefits of reducing acute cardiorespiratory morbidity related to air pollution have employed a comprehensive, explicit approach to capturing the full societal value of reduced morbidity. METHODS: We used empiri ...
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Journal ArticleHealth Serv Res · December 2002
OBJECTIVE: To examine preferences for HIV test methods using conjoint analysis, a method used to measure economic preferences (utilities). DATA SOURCES: Self-administered surveys at four publicly funded HIV testing locations in San Francisco, California, b ...
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Journal ArticleHealth Serv Res · December 2002
OBJECTIVE: To compare and contrast methods and findings from two approaches to valuation used in the same survey: measurement of "attitudes" using simple rankings and ratings versus measurement of "preferences" using conjoint analysis. Conjoint analysis, a ...
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Journal ArticleReview of Economics and Statistics · November 1, 2001
This paper reports the first effort to use data to evaluate how new information, acquired through exogenous health shocks, affects people's longevity expectations. We find that smokers react differently to health shocks than do those who quit smoking or ne ...
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Journal ArticleValue Health · 2001
This paper presents a dynamic generalization of a model often used to aid marketing decisions relating to conventional products. The model uses stated-preference data in a random-utility framework to predict adoption rates for new pharmaceutical products. ...
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ConferenceAmerican Journal of Agricultural Economics · January 1, 2001
Economists increasingly are turning to multiple-response stated-preference (SP) methods (sometimes called conjoint analysis) to value environmental and natural-resource commodities (Gan and Luzar; Opaluch et al.; Roe, Boyle, and Teisl; Adamowicz, Louviere, ...
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Journal ArticleGrowth and Change · January 1, 2001
Measuring nonuse values is one of the most controversial topics facing environmental economists today. One important issue that has received little attention is determining who has economic standing with respect to nonuse losses from natural resource injur ...
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Journal ArticleHealth Econ · June 2000
This study uses stated-preference (SP) analysis to measure willingness to pay (WTP) to reduce acute episodes of respiratory and cardiovascular ill health. The SP survey employs a modified version of the health state descriptions used in the Quality of Well ...
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Journal ArticleJournal of Environmental Economics and Management · January 1, 2000
Morey and Waldman have proposed a method for handling measurement error in site attributes, such as catch rates in models of anglers' choice of fishing sites. We discuss the properties of this method and compare these properties with those of the standard ...
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Journal ArticleMed Decis Making · 1998
The economic analysis of many health policies requires evaluation of the benefits of programs that may prolong human lives. This article contributes to the development of credible values for longevity, demonstrating the feasibility of applying stated-prefe ...
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Journal ArticleMedical Decision Making · January 1998
Decision and cost-utility analyses considered the tradeoffs of treating patent ductus arteriosus (PDA) using conventional surgery versus transcatheter implantation of the Rashkind occluder. Physicians and informed lay parents assigned utility scor ...
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Journal ArticleJ Health Econ · December 1997
Placing dollar values on human health has long been a controversial aspect of policy analysis and remains difficult given the relatively small number of morbidity-valuation studies available. By combining both the economic and health literature, this paper ...
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Journal ArticleContemporary Economic Policy · January 1, 1997
This article examines economic and legal constraints that determine whose losses are included in natural resource damages as a result of an oil spill or hazardous-substance release. For example, the article describes the circumstances under which use losse ...
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Journal ArticleJournal of Environmental Economics and Management · January 1, 1997
Respondents' stated preferences for attributes related to various electricity-generation scenarios are analyzed using a series of pairwise ratings. Multiple observations for each respondent facilitate estimating individual scale parameters. Scale estimates ...
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Journal ArticleLand Economics · January 1, 1996
Independent applications of openended and dichotomous-choice formats are compared using tests of means, estimating joint likelihood functions and nonparametric tests of distributions. The null hypothesis of no difference in the open-ended and dichotomous-c ...
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Journal ArticleResource and Energy Economics · January 1, 1996
This paper summarizes the research strategy adopted in developing separate estimates of environmental costs for two major private utility systems. One of the systems, North States Power Company in Minnesota, is used to describe the model structure. Particu ...
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Journal ArticleJournal of Environmental Economics and Management · January 1, 1994
Part-whole bias is a possible explanation for nonuse contingent-valuation estimates that are insensitive to marginal changes in environmental commodities. Our empirical analyses reveal no statistically significant differences in willingness to pay of indep ...
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Journal ArticleWater Resources Research · January 1, 1992
This study quantifies local improvements in environmental quality from controlling effluents in the pulp and paper industry. Although it is confined to a single industry, this study is the first effort to assess the actual net benefits of the Clean Water A ...
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Journal ArticleJ Air Waste Manage Assoc · May 1990
Those responsible for state and local radon programs often express frustration about the small share of homes that have been tested for radon, and the small share of those with high readings that have been mitigated. There are now a number of completed stu ...
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Journal ArticleJournal of Policy Analysis and Management · January 1, 1990
This article provides the first controlled evaluation of how different information materials explaining the risks from radon influenced people's perceptions of these risks. Using a panel study, it was possible to observe how stated risk perceptions respond ...
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Journal ArticleNatural Resources Journal · January 1, 1990
Given the probable large number of sites contaminated with hazardous wastes, there could be significant benefits from a statutory system that effectively deters future contamination and encourages private remediation of existing sites. We compare the effec ...
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Journal ArticleRisk Analysis · January 1, 1989
A recent comprehensive review of the literature identified a number of facts and principles governing risk communication. This paper evaluates several of these propositions using recent evidence from a field experiment in communicating the risks from radon ...
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Journal ArticleRisk Anal · June 1988
This study reports results of an analysis of consumer responses to news reports of grain-product contamination by the pesticide ethylene dibromide (EDB). The results demonstrate that it is possible to quantify market disruption related to the dissemination ...
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Journal ArticleJournal of Risk and Uncertainty · June 1, 1988
This article reports the results of an evaluation of the effectiveness of different types of information materials in communicating the risk from exposure to radon, a naturally occurring indoor air pollutant. The study involved a panel of 2300 homeowners w ...
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Journal ArticleEnvironment · January 1, 1988
This article reports some preliminary results of a recent social experiment designed to test the senstivity of people's responses to alternative presentations of the same facts about radon risks. Ethical issues enter the experiment in two ways. First, it w ...
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Journal ArticleReview of Economics & Statistics · January 1, 1988
A specialized survey of Maine household's responses to information about the risks associated with radon concentrations in their homes and water supplies was used to evaluate how they form risk perceptions. The findings support a modified form of a Bayesia ...
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Journal ArticleRisk Anal · March 1987
This study examines the perceived risks and mitigating behavior of Maine households who received new information on their exposures to significant health risks from indoor radon. The observed responses of these households illustrate conceptual issues relat ...
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Journal ArticleJournal of Environmental Management · January 1, 1982
Presents a model of natural resource allocation which admits consideration of a class of public policy issues involving reversibility and substitutability. The development-conservation tradeoff is characterized as incorporating a wide range of options incl ...
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Journal ArticleLand Economics · January 1, 1982
One widely accepted technique for estimating the willingness to pay for a recreation site in CBA is the travel cost method. This study examines the consequences of multiple destination trips on travel cost estimates of benefits. It also suggests a means of ...
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Journal ArticleLand Economics · January 1, 1981
Extends the Krutilla-Fisher valuation technique for resource sites to cases where the resource in question is not unique, as assumed in previous studies, but has recognized substitutes. In this process, it is demonstrated that vertical and horizontal deman ...
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Journal ArticleResources Policy · January 1, 1981
A model of resource evaluation incorporating reversibility of actions and substitutability for resource services is presented, along with associated decision criteria. The model extends and generalizes the Krutilla-Fisher procedure for evaluating unique re ...
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Journal ArticleJournal of Forestry · January 1, 1980
While some of the criticism of the travel-cost methods of estimating benefits of outdoor recreation is with-out basis, serious problems of utility or disutility of travel, joint visitation, and data deficiencies do limit accuracy of the estimates. This met ...
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Journal ArticleReview of Social Economy · January 1, 1979
It has always been a cardinal teaching with the Latter-day Saints that a religion that has not the power to save people temporally and make them prosperous and happy here cannot be depended upon to save them spiritually and to exalt them in the life to com ...
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