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Henry Ryan Wagner II

Adjunct Associate Professor in the Department of Psychiatry and Behavioral Sciences
Psychiatry, Child & Family Mental Health & Community Psychiatry
Box 3454 Med Ctr, Durham, NC 27710
Brightleaf SQ Ste 22B, 905 W Main St, Durham, NC 27701

Selected Publications


Anger and suicidality in veterans: Impact of postseparation time and combat.

Journal Article Psychol Trauma · October 2024 OBJECTIVE: The study investigated the association over time between the rates of anger/hostility and suicidality in post-9/11 veterans as a function of time following separation from the military and combat exposure. METHOD: Structured clinical interviews ... Full text Open Access Link to item Cite

Effects of mTBI with loss of consciousness on neurobehavioral symptoms, depression, and insomnia in former collegiate and NFL football athletes.

Journal Article Brain Inj · September 18, 2024 OBJECTIVE: Considering that diagnostic decisions about mTBI are often predicated on clinical symptom criteria, it is imperative to determine which initial presentation features of mTBI have prognostic significance for identifying those at high risk for lon ... Full text Link to item Cite

Socioeconomic Correlates of Suicidal Ideation in Military Veterans: Examining the Interaction Between Homelessness and Financial Debt.

Journal Article Community Ment Health J · August 7, 2024 Studies in veterans have yet to examine interconnections between homelessness, financial debt, and suicidal ideation. We analyzed data from a nationally-representative study conducted in 2021 of low-income U.S. veterans (Nā€‰=ā€‰1,004). Analyses revealed veter ... Full text Link to item Cite

Deployment-related toxic exposures are associated with worsening mental and physical health after military service: Results from a self-report screening of veterans deployed after 9/11.

Journal Article J Psychiatr Res · June 2024 Exposure to toxins-such as heavy metals and air pollution-can result in poor health and wellbeing. Recent scientific and media attention has highlighted negative health outcomes associated with toxic exposures for U.S. military personnel deployed overseas. ... Full text Link to item Cite

Posttraumatic stress disorder, trauma, and accelerated biological aging among post-9/11 veterans.

Journal Article Transl Psychiatry · January 6, 2024 People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain this risk is accelerated biological aging, which is associated with the accumulation of chronic diseases, ... Full text Open Access Link to item Cite

Food Insecurity and Suicidal Ideation: Results from a National Longitudinal Study of Military Veterans.

Journal Article Arch Suicide Res · 2024 OBJECTIVE: Research examining social determinants of suicide risk in veterans suggests a potential link between food insecurity and subsequent suicidal ideation in military veterans. The objective of this study is to investigate, if and how, food insecurit ... Full text Link to item Cite

Personality Assessment Inventory suicidality scales: Suicidal Ideation (SUI), Suicide Potential Index (SPI), and S_Chron in an Afghanistan/Iraq-era active and Veteran military sample.

Journal Article Suicide Life Threat Behav · June 2023 INTRODUCTION: This study validated Personality Assessment Inventory (PAI) Suicidal Ideation (SUI), Suicide Potential Index (SPI), and S_Chron scales against chronic and acute suicide risk factors and symptom validity measures. METHODS: Afghanistan/Iraq-era ... Full text Link to item Cite

How often does homelessness precede criminal arrest in veterans? Results from the U.S. survey of prison inmates.

Journal Article Am J Orthopsychiatry · 2023 Research has shown links between homelessness and criminal legal involvement in military veterans. The present study aimed to determine the magnitude and directionality of this association by investigating the incidence of, and factors associated with, hom ... Full text Link to item Cite

A National Study of Zoom Fatigue and Mental Health During the COVID-19 Pandemic: Implications for Future Remote Work.

Journal Article Cyberpsychol Behav Soc Netw · July 2022 Overuse of videoconferencing for work may contribute to what has been called "Zoom fatigue": feeling anxious, socially isolated, or emotionally exhausted due to lack of social connection. Given implications for employee well-being, this study investigated ... Full text Link to item Cite

Psychosocial well-being among veterans with posttraumatic stress disorder and substance use disorder.

Journal Article Psychol Trauma · March 2022 OBJECTIVE: Concurrent posttraumatic stress disorder and substance use disorder (PTSD/SUD) in U.S. military veterans represents an urgent public health issue associated with significant clinical challenges. Although previous research has shown that veterans ... Full text Link to item Cite

The role of trauma, social support, and demography on veteran resilience.

Journal Article Eur J Psychotraumatol · 2022 BACKGROUND: Historically, resilience has often been conceptualized as the sustained lack of symptoms following trauma exposure. In line with a novel conceptualization of resilience as being dynamic over lifespan, determined by interacting biological and en ... Full text Link to item Cite

Sex differences in predictors of recurrent major depression among current-era military veterans.

Journal Article Psychol Serv · May 2021 Although major depressive disorder (MDD) is a frequent diagnosis among women seeking care in the Veterans Health Administration, little is known about its course. For example, recurrence of MDD and its predictors have been investigated in civilians, but no ... Full text Link to item Cite

Suicidal ideation and thoughts of self-harm during the COVID-19 pandemic: The role of COVID-19-related stress, social isolation, and financial strain.

Journal Article Depression and anxiety · May 2021 BackgroundThere are significant concerns about mental health problems occurring due to the coronavirus disease 2019 (COVID-19) pandemic. To date, there has been limited empirical investigation about thoughts of suicide and self-harm during the COV ... Full text Cite

Financial Strain, Mental Illness, and Homelessness: Results From a National Longitudinal Study.

Journal Article Med Care · April 1, 2021 BACKGROUND: Research indicates that adults with severe mental illness have lower income and employment than adults without severe mental illness. Further, mental illness has been identified as a risk factor for homelessness. However, little research has in ... Full text Link to item Cite

Financial Strain and Suicide Attempts in a Nationally Representative Sample of US Adults.

Journal Article Am J Epidemiol · November 2, 2020 Although research has identified many suicide risk factors, the relationship between financial strain and suicide has received less attention. Using data representative of the US adult population (nĀ =Ā 34,653) from wave 1 (2001-2002) and wave 2 (2004-2005) ... Full text Link to item Cite

Neural correlates of conceptual-level fear generalization in posttraumatic stress disorder.

Journal Article Neuropsychopharmacology · July 2020 Posttraumatic stress disorder (PTSD) may develop when mechanisms for making accurate distinctions about threat relevance have gone awry. Generalization across conceptually related objects has been hypothesized based on clinical observation in PTSD, but the ... Full text Link to item Cite

Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial.

Journal Article JAMA Netw Open · March 2, 2020 IMPORTANCE: In response to the national opioid public health crisis, there is an urgent need to develop nonopioid solutions for effective pain management. Neurosteroids are endogenous molecules with pleotropic actions that show promise for safe and effecti ... Full text Link to item Cite

Amygdala Nuclei Volume and Shape in Military Veterans With Posttraumatic Stress Disorder.

Journal Article Biol Psychiatry Cogn Neurosci Neuroimaging · March 2020 BACKGROUND: The amygdala is a subcortical structure involved in socioemotional and associative fear learning processes relevant for understanding the mechanisms of posttraumatic stress disorder (PTSD). Research in animals indicates that the amygdala is a h ... Full text Link to item Cite

Combat exposure, posttraumatic stress disorder, and head injuries differentially relate to alterations in cortical thickness in military Veterans.

Journal Article Neuropsychopharmacology · February 2020 Combat-exposed Veterans are at increased risk for developing psychological distress, mood disorders, and trauma and stressor-related disorders. Trauma and mood disorders have been linked to alterations in brain volume, function, and connectivity. However, ... Full text Link to item Cite

Psychosocial protective factors and suicidal ideation: Results from a national longitudinal study of veterans.

Journal Article J Affect Disord · January 1, 2020 BACKGROUND: This study investigates the empirical association between psychosocial protective factors and subsequent suicidal ideation in veterans. METHODS: We conducted a national longitudinal survey in which participants were randomly drawn from over one ... Full text Link to item Cite

Neurosteroids in TBI: Biomarkers to Therapeutics

Conference NEUROPSYCHOPHARMACOLOGY · December 1, 2019 Link to item Cite

Pain Intensity and Pain Interference in Male and Female Iraq/Afghanistan-era Veterans.

Journal Article Womens Health Issues · June 25, 2019 BACKGROUND: Chronic pain conditions are common among both male and female Iraq/Afghanistan-era veterans and can have substantial negative impacts on quality of life and function. Although in general women tend to report higher levels of pain intensity than ... Full text Link to item Cite

An Evaluation of the Effectiveness of Evidence-Based Psychotherapies for Depression to Reduce Suicidal Ideation among Male and Female Veterans.

Journal Article Womens Health Issues · June 25, 2019 BACKGROUND: Although most suicide-related deaths occur among male veterans, women veterans are dying by suicide in increasing numbers. Identifying and increasing access to effective treatments is imperative for Department of Veterans Affairs suicide preven ... Full text Link to item Cite

The central role of disgust in disorders of food avoidance.

Journal Article Int J Eat Disord · May 2019 BACKGROUND: Individuals with extreme food avoidance such as Avoidant Restrictive Food Intake Disorder (ARFID) experience impairing physical and mental health consequences from nutrition of insufficient variety or/and quantity. Identifying mechanisms contri ... Full text Link to item Cite

Relationship between traumatic brain injury history and recent suicidal ideation in Iraq/Afghanistan-era veterans.

Journal Article Psychol Serv · May 2019 This study evaluated whether a history of traumatic brain injury (TBI) was associated with increased risk for recent suicidal ideation (SI) after accounting for demographics, depression, posttraumatic stress disorder (PTSD), and sleep quality. In terms of ... Full text Link to item Cite

Anger, social support, and suicide risk in U.S. military veterans.

Journal Article J Psychiatr Res · February 2019 There have been considerable efforts to understand, predict, and reduce suicide among U.S. military veterans. Studies have shown that posttraumatic stress disorder (PTSD), major depression (MDD), and traumatic brain injury (TBI) increase risk of suicidal b ... Full text Link to item Cite

Cognitive Rehabilitation With Mobile Technology and Social Support for Veterans With TBI and PTSD: A Randomized Clinical Trial.

Journal Article J Head Trauma Rehabil · 2019 OBJECTIVE: To investigate effects of cognitive rehabilitation with mobile technology and social support on veterans with traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD). PARTICIPANTS: There were 112 dyads, comprised by a veteran and a ... Full text Link to item Cite

Widespread Cortical Thickness Is Associated With Neuroactive Steroid Levels.

Journal Article Front Neurosci · 2019 BACKGROUND: Neuroactive steroids are endogenous molecules with regenerative and neuroprotective actions. Both cortical thickness and many neuroactive steroid levels decline with age and are decreased in several neuropsychiatric disorders. However, a system ... Full text Open Access Link to item Cite

Smaller hippocampal CA1 subfield volume in posttraumatic stress disorder.

Journal Article Depress Anxiety · November 2018 BACKGROUND: Smaller hippocampal volume in patients with posttraumatic stress disorder (PTSD) represents the most consistently reported structural alteration in the brain. Subfields of the hippocampus play distinct roles in encoding and processing of memori ... Full text Link to item Cite

Psychosocial Risk Factors and Other Than Honorable Military Discharge: Providing Healthcare to Previously Ineligible Veterans.

Journal Article Mil Med · September 1, 2018 INTRODUCTION: In response to a strong focus on suicide prevention for all veterans, the Department of Veterans Affairs (VA) recently revised policy to provide emergency mental healthcare for veterans who received Other Than Honorable (OTH) discharges from ... Full text Link to item Cite

The Association Between Military Sexual Trauma and Use of VA and Non-VA Health Care Services Among Female Veterans With Military Service in Iraq or Afghanistan.

Journal Article J Interpers Violence · August 2018 Military sexual trauma (MST) has been linked with increased rates of mental health disorders among veterans. Few studies have addressed how MST is related to use of VA and non-VA health care. The purpose of the current study was to (a) examine the associat ... Full text Link to item Cite

Chronic Pain, TBI, and PTSD in Military Veterans: A Link to Suicidal Ideation and Violent Impulses?

Journal Article J Pain · July 2018 UNLABELLED: The polytrauma clinical triad refers to the co-occurrence of chronic pain, traumatic brain injury (TBI), and posttraumatic stress disorder (PTSD). Despite research implicating dyadic relationships between these conditions and adverse outcomes, ... Full text Link to item Cite

Effects of social support and resilient coping on violent behavior in military veterans.

Journal Article Psychol Serv · May 2018 Violence toward others has been identified as a serious postdeployment adjustment problem in a subset of Iraq- and Afghanistan-era veterans. In the current study, we examined the intricate links between posttraumatic stress disorder (PTSD), commonly cited ... Full text Link to item Cite

Risk factors for concurrent suicidal ideation and violent impulses in military veterans.

Journal Article Psychol Assess · April 2018 Suicide and violence are significant problems in a subset of Iraq/Afghanistan-era veterans. This study investigates how posttraumatic stress disorder (PTSD) and resilience in veterans are associated with suicidal ideation and violent impulses while control ... Full text Link to item Cite

Does Deployment-Related Military Sexual Assault Interact with Combat Exposure to Predict Posttraumatic Stress Disorder in Female Veterans?

Journal Article Traumatology (Tallahass Fla) · 2018 The objective of the present research was to expand upon previous findings indicating that military sexual trauma interacts with combat exposure to predict PTSD among female Iraq/Afghanistan-era veterans. Three hundred and thirty female veterans completed ... Link to item Cite

Smaller Hippocampal CA-1 Subfield Volume in Posttraumatic Stress Disorder

Journal Article · 2018 Background Smaller hippocampal volume in patients with PTSD represents the most consistently reported structural alteration in the brain. Subfields of the hippocampus play distinct roles in encoding and processing of memories, which are disrupted ... Full text Cite

Paternal history of mental illness associated with posttraumatic stress disorder among veterans.

Journal Article Psychiatry Res · October 2017 This study examined the association between parent and family reported history of non-PTSD mental illness (MI), PTSD specifically, and substance use problems, and participant clinical diagnosis of PTSD. Participants were drawn from the US Department of Vet ... Full text Link to item Cite

Acceptance-based interoceptive exposure for young children with functional abdominal pain.

Journal Article Behav Res Ther · October 2017 UNLABELLED: Functional abdominal pain (FAP) is a common childhood somatic complaint that contributes to impairment in daily functioning (e.g., school absences) and increases risk for chronic pain and psychiatric illness. Cognitive behavioral treatments for ... Full text Link to item Cite

Self-Reported Pain in Male and Female Iraq/Afghanistan-Era Veterans: Associations with Psychiatric Symptoms and Functioning.

Journal Article Pain Med · September 1, 2017 OBJECTIVE: To examine pain symptoms and co-occurring psychiatric and functional indices in male and female Iraq/Afghanistan-era veterans. DESIGN: Self-reported data collection and interviews of Iraq/Afghanistan-era veterans who participated in a multisite ... Full text Link to item Cite

The Post-Deployment Mental Health (PDMH) study and repository: A multi-site study of US Afghanistan and Iraq era veterans.

Journal Article Int J Methods Psychiatr Res · September 2017 The United States (US) Department of Veterans Affairs (VA) Mid-Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC) Post-Deployment Mental Health (PDMH) multi-site study examines post-deployment mental health in US military Afghanistan ... Full text Link to item Cite

Medication compliance

Book · July 2017 Differing terms are used for compliance, including concordance and adherence. This chapter examines the range of obstacles to compliance, including side effects, lack of insight, lack of effectiveness, and resistance to being reminded of the illness. Th ... Full text Cite

Cannabis use disorder and suicide attempts in Iraq/Afghanistan-era veterans.

Journal Article J Psychiatr Res · June 2017 The objective of the present research was to examine the association between lifetime cannabis use disorder (CUD), current suicidal ideation, and lifetime history of suicide attempts in a large and diverse sample of Iraq/Afghanistan-era veterans (NĀ =Ā 3233) ... Full text Link to item Cite

Does Model Matter? Examining Change Across Time for Youth in Group Homes.

Journal Article J Emot Behav Disord · June 2017 Group homes are a frequently used but controversial treatment setting for youth with mental health problems. Within the relatively sparse literature on group homes, there is some evidence that some models of treatment may be associated with more positive o ... Full text Link to item Cite

The Clinical Significance of Posterior Insular Volume in Adolescent Anorexia Nervosa.

Journal Article Psychosom Med · 2017 OBJECTIVE: The diagnostic criterion disturbance in the experience of the body remains a poorly understood and persistent feature of anorexia nervosa (AN). Increased sophistication in understanding the structure of the insular cortex-a neural structure that ... Full text Link to item Cite

The prevalence of binge drinking and receipt of provider drinking advice among US veterans with military service in Iraq or Afghanistan.

Journal Article Am J Drug Alcohol Abuse · May 2016 BACKGROUND: Binge drinking is a significant public health concern linked to a number of health and psychosocial problems. Military service in Afghanistan (OEF) and Iraq (OIF) has been associated with posttraumatic stress disorder (PTSD) and increased hazar ... Full text Link to item Cite

Subthreshold posttraumatic stress disorder: A meta-analytic review of DSM-IV prevalence and a proposed DSM-5 approach to measurement.

Journal Article Psychol Trauma · March 2016 Subthreshold posttraumatic stress disorder (PTSD) is a chronic condition that is often ignored, the cumulative effects of which can negatively impact an individual's quality of life and overall health care costs. However, subthreshold PTSD prevalence rates ... Full text Link to item Cite

Who Goes Where? Exploring Factors Related to Placement Among Group Homes.

Journal Article J Emot Behav Disord · March 2016 Despite their widespread use as a placement option for youth with mental health problems, there is relatively little research on group homes for youth. Available data highlight concerns with practices and treatment within group homes and mixed results on y ... Full text Link to item Cite

Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.

Journal Article Pain Med · January 2016 BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans, many of whom continue to experience persistent pain symptoms despite multiple pharmacological interventions. Preclinical data suggest that neurosteroids such as allopr ... Full text Open Access Link to item Cite

An exploratory pilot investigation of neurosteroids and self-reported pain in female Iraq/Afghanistan-era Veterans.

Journal Article J Rehabil Res Dev · 2016 Female Veterans are the most rapidly growing segment of new users of the Veterans Health Administration (VHA), and a significant proportion of female Veterans receiving treatment from VHA primary care providers report persistent pain symptoms. Currently, a ... Full text Link to item Cite

Fear learning circuitry is biased toward generalization of fear associations in posttraumatic stress disorder.

Journal Article Transl Psychiatry · December 15, 2015 Fear conditioning is an established model for investigating posttraumatic stress disorder (PTSD). However, symptom triggers may vaguely resemble the initial traumatic event, differing on a variety of sensory and affective dimensions. We extended the fear-c ... Full text Open Access Link to item Cite

Functional correlates of military sexual assault in male veterans.

Journal Article Psychol Serv · November 2015 Despite research findings that similar numbers of male and female veterans are affected by military sexual trauma (MST), there has been considerably less research on the effects of MST specific to male veterans. The aim of the present study was to provide ... Full text Link to item Cite

Prolonged Exposure Therapy With Veterans and Active Duty Personnel Diagnosed With PTSD and Traumatic Brain Injury.

Journal Article J Trauma Stress · August 2015 The present study used archival clinical data to analyze the delivery and effectiveness of prolonged exposure (PE) and ancillary services for posttraumatic stress disorder (PTSD) among Operation Enduring Freedom, Operation Iraqi Freedom, and Operation New ... Full text Link to item Cite

A pilot randomized placebo-controlled trial of adjunctive aripiprazole for chronic PTSD in US military Veterans resistant to antidepressant treatment.

Journal Article Int Clin Psychopharmacol · May 2015 Many individuals with post-traumatic stress disorder (PTSD) experience persistent symptoms despite pharmacological treatment with antidepressants. Several open-label monotherapy and adjunctive studies have suggested that aripiprazole (a second-generation a ... Full text Link to item Cite

Patterns of maltreatment and diagnosis across levels of care in group homes.

Journal Article Child Abuse Negl · April 2015 Patterns of Axis I psychiatric diagnosis and maltreatment history were explored among youth in group homes, including match of clinical need to level or restrictiveness of care. Data on demographics, diagnoses, maltreatment, and group home level of care (L ... Full text Link to item Cite

The prevalence of posttraumatic stress disorder in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans: a meta-analysis.

Journal Article J Anxiety Disord · April 2015 Literature on posttraumatic stress disorder (PTSD) prevalence among Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) veterans report estimates ranging from 1.4% to 60%. A more precise estimate is necessary for projecting healthcare needs and informi ... Full text Link to item Cite

Surveying treatment preferences in U.S. Iraq-Afghanistan Veterans with PTSD symptoms: a step toward veteran-centered care.

Journal Article J Trauma Stress · April 2015 This study examined health care barriers and preferences among a self-selected sample of returning U.S. veterans drawn from a representative, randomly selected frame surveyed about posttraumatic stress disorder (PTSD) symptomatology and mental health utili ... Full text Link to item Cite

Self-focused attention in anorexia nervosa.

Journal Article Int J Eat Disord · January 2015 OBJECTIVE: The clinical presentation of anorexia nervosa (AN) is characterized by preoccupation with body experience, intrusive concerns regarding shape, and pathological fears of weight gain. These symptoms are suggestive of unrelenting self-focused atten ... Full text Link to item Cite

The factor structure of psychiatric comorbidity among Iraq/Afghanistan-era veterans and its relationship to violence, incarceration, suicide attempts, and suicidality.

Journal Article Psychiatry Res · December 15, 2014 The present research examined how incarceration, suicide attempts, suicidality, and difficulty controlling violence relate to the underlying factor structure of psychiatric comorbidity among a large sample of Iraq/Afghanistan-era veterans (N=1897). Diagnos ... Full text Link to item Cite

Screening for violence risk in military veterans: predictive validity of a brief clinical tool.

Journal Article Am J Psychiatry · July 2014 OBJECTIVE: Violence toward others is a serious problem among a subset of military veterans. The authors evaluated the predictive validity of a brief decision support tool to screen veterans for problems with violence and identify potential candidates for a ... Full text Link to item Cite

The impact of social support on psychological distress for U.S. Afghanistan/Iraq era veterans with PTSD and other psychiatric diagnoses.

Journal Article Psychiatry Res · June 30, 2014 This study aimed to examine the degree to which posttraumatic stress disorder (PTSD) affects the relationship between social support and psychological distress for U.S. Afghanistan/Iraq era veterans with and without co-occurring psychiatric disorders. Vete ... Full text Link to item Cite

Use of Psychotropic Medications among Youth in Treatment Foster Care.

Journal Article J Child Fam Stud · May 1, 2014 We describe the use of psychotropic medications among youth in treatment foster care (TFC). Data from 240 youth were coded to examine rates of medication use, including polypharmacy and an indicator of "questionable polypharmacy." Fifty-nine percent of you ... Full text Link to item Cite

Protective mechanisms and prevention of violence and aggression in veterans.

Journal Article Psychol Serv · May 2014 Although a subset of Iraq and Afghanistan Veterans show aggression toward others after they return home from military service, little is known about protective mechanisms that could be bolstered to prevent violence. A national longitudinal survey was condu ... Full text Link to item Cite

Family Involvement in Treatment Foster Care.

Journal Article Resid Treat Child Youth · January 2, 2014 Child mental health policy and practice has increasingly embraced family-driven practice which promotes family involvement in all aspects of planning and service delivery. While evidence for positive outcomes related to family involvement is mounting in tr ... Full text Link to item Cite

Dannia Southerland, 1950ā€“2013

Journal Article Residential Treatment for Children & Youth · January 2, 2014 Full text Cite

Violent behaviour and post-traumatic stress disorder in US Iraq and Afghanistan veterans.

Journal Article Br J Psychiatry · 2014 BACKGROUND: Violence towards others in the community has been identified as a significant problem for a subset of Iraq and Afghanistan veterans. AIMS: To investigate the extent to which post-traumatic stress disorder (PTSD) and other risk factors predict f ... Full text Link to item Cite

Homelessness and money mismanagement in Iraq and Afghanistan veterans.

Journal Article Am J Public Health · December 2013 OBJECTIVES: We examined the empirical link between money mismanagement and subsequent homelessness among veterans. METHODS: We used a random sample of Iraq and Afghanistan War era veterans from the National Post-Deployment Adjustment Survey in 2009-2011. R ... Full text Link to item Cite

Self-report and longitudinal predictors of violence in Iraq and Afghanistan war era veterans.

Journal Article J Nerv Ment Dis · October 2013 This study, using a longitudinal design, attempted to identify whether self-reported problems with violence were empirically associated with future violent behavior among Iraq and Afghanistan war veterans and whether and how collateral informant interviews ... Full text Link to item Cite

Neuropsychological predictors of dementia in late-life major depressive disorder.

Journal Article Am J Geriatr Psychiatry · March 2013 OBJECTIVE: Major depressive disorder is a likely risk factor for dementia, but some cases of major depressive disorder in older adults may actually represent a prodrome of this condition. The purpose of this study was to use neuropsychological test scores ... Full text Link to item Cite

Are Iraq and Afghanistan veterans using mental health services? New data from a national random-sample survey.

Journal Article Psychiatr Serv · February 1, 2013 OBJECTIVE: This study analyzed data from a national survey of Iraq and Afghanistan veterans to improve understanding of mental health services use and perceived barriers. METHODS: The National Post-Deployment Adjustment Survey randomly sampled post-9/11 ve ... Full text Link to item Cite

Protective Factors and Risk Modification of Violence in Iraq and Afghanistan War Veterans

Journal Article Yearbook of Psychiatry and Applied Mental Health · January 2013 Full text Cite

Perception of affect in biological motion cues in anorexia nervosa.

Journal Article Int J Eat Disord · January 2013 OBJECTIVE: Nonverbal motion cues (a clenched fist) convey essential information about the intentions of the actor. Individuals with anorexia nervosa (AN) have demonstrated impairment in deciphering intention from facial affective cues, but it is unknown wh ... Full text Link to item Cite

Emotion regulation difficulties in anorexia nervosa: Relationship to self-perceived sensory sensitivity.

Journal Article Cogn Emot · 2013 Changes in sensation (e.g., prickly skin) are crucial constituents of emotional experience, and the intensity of perceived changes has been linked to emotional intensity and dysregulation. The current study examined the relationship between sensory sensiti ... Full text Link to item Cite

Criminal justice involvement, trauma, and negative affect in Iraq and Afghanistan war era veterans.

Journal Article J Consult Clin Psychol · December 2012 OBJECTIVE: Although criminal behavior in veterans has been cited as a growing problem, little is known about why some veterans are at increased risk for arrest. Theories of criminal behavior postulate that people who have been exposed to stressful environm ... Full text Link to item Cite

Zonisamide for weight reduction in obese adults: a 1-year randomized controlled trial.

Journal Article Arch Intern Med · November 12, 2012 BACKGROUND: Obese individuals who have failed to achieve adequate weight loss with lifestyle changes have limited nonsurgical therapeutic options. We evaluated the efficacy and tolerability of zonisamide, an antiepileptic drug, for enhancing weight loss in ... Full text Link to item Cite

Amygdala volume changes in posttraumatic stress disorder in a large case-controlled veterans group.

Journal Article Arch Gen Psychiatry · November 2012 CONTEXT: Smaller hippocampal volumes are well established in posttraumatic stress disorder (PTSD), but the relatively few studies of amygdala volume in PTSD have produced equivocal results. OBJECTIVE: To assess a large cohort of recent military veterans wi ... Full text Open Access Link to item Cite

Zonisamide for Weight Reduction in Obese Adults: A 1-Year Randomized Controlled Trial.

Journal Article Arch Intern Med · October 15, 2012 BACKGROUND Obese individuals who have failed to achieve adequate weight loss with lifestyle changes have limited nonsurgical therapeutic options. We evaluated the efficacy and tolerability of zonisamide, an antiepileptic drug, for enhancing weight loss in ... Full text Link to item Cite

Prior Trauma Exposure for Youth in Treatment Foster Care.

Journal Article J Child Fam Stud · October 2012 Very little research has focused on rates of trauma exposure for youth in treatment foster care (TFC). Available research has utilized record review for assessing exposure, which presents limitations for the range of trauma types examined, as records are p ... Full text Link to item Cite

Protective factors and risk modification of violence in Iraq and Afghanistan War veterans.

Journal Article J Clin Psychiatry · June 2012 OBJECTIVE: After returning home, a subset of Iraq and Afghanistan War veterans report engaging in aggression toward others. This study is the first to identify variables empirically related to decreased risk of community violence among veterans. METHOD: Th ... Full text Link to item Cite

Financial well-being and postdeployment adjustment among Iraq and Afghanistan war veterans.

Journal Article Mil Med · June 2012 Research has yet to examine the relationship between financial well-being and community reintegration of veterans. To address this, we analyzed data from n = 1,388 Iraq and Afghanistan War Era Veterans who completed a national survey on postdeployment adju ... Full text Link to item Cite

Neuropsychological Predictors of Dementia in Late-Life Major Depressive Disorder.

Journal Article Am J Geriatr Psychiatry · March 11, 2012 OBJECTIVE:: Major depressive disorder is a likely risk factor for dementia, but some cases of major depressive disorder in older adults may actually represent a prodrome of this condition. The purpose of this study was to use neuropsychological test scores ... Full text Link to item Cite

The effect of nicotine and trauma context on acoustic startle in smokers with and without posttraumatic stress disorder.

Journal Article Psychopharmacology (Berl) · May 2011 RATIONALE: Exaggerated startle response is a prominent feature of posttraumatic stress disorder (PTSD) although results examining differences in the acoustic startle response (ASR) between those with and without PTSD are mixed. One variable that may affect ... Full text Link to item Cite

Scan-rescan reliability of subcortical brain volumes derived from automated segmentation.

Journal Article Hum Brain Mapp · November 2010 Featured Publication Large-scale longitudinal studies of regional brain volume require reliable quantification using automated segmentation and labeling. However, repeated MR scanning of the same subject, even if using the same scanner and acquisition parameters, does not resu ... Full text Open Access Link to item Cite

Correlates of anger and hostility in Iraq and Afghanistan war veterans.

Journal Article Am J Psychiatry · September 2010 OBJECTIVE: As troops return from Iraq and Afghanistan to civilian life, clinicians are starting to grapple with how best to detect those at risk of postdeployment adjustment problems. Data reveal the presence of mental health problems in these soldiers, in ... Full text Link to item Cite

Service use and multi-sector use for mental health problems by youth in contact with child welfare

Journal Article Children and Youth Services Review · June 1, 2010 This article uses data from the National Survey of Child and Adolescent Well-Being (NSCAW) to examine multi-sector service use for mental health problems by youth in contact with social service agencies. At 18-months post-investigation for abuse/neglect, 2 ... Full text Cite

Sleep disturbance and baroreceptor sensitivity in women with posttraumatic stress disorder.

Journal Article J Trauma Stress · December 2009 Featured Publication In a previous study, women with posttraumatic stress disorder (PTSD) had greater objective sleep disturbance than those without PTSD. In a separate previous study, women with PTSD were also found to have lower baroreceptor sensitivity (BRS), an index of bl ... Full text Link to item Cite

Rebuttal to Hasan and Pedraza in comments and controversies: "Improving the reliability of manual and automated methods for hippocampal and amygdala volume measurements".

Journal Article Neuroimage · November 15, 2009 Featured Publication Here we address the critiques offered by Hasan and Pedraza to our recently published manuscript comparing the performance of two automated segmentation programs, FSL/FIRST and FreeSurfer (Morey R, Petty C, Xu Y, Pannu Hayes J, Wagner H, Lewis D, LaBar K, S ... Full text Link to item Cite

A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes.

Journal Article Neuroimage · April 15, 2009 Featured Publication Large databases of high-resolution structural MR images are being assembled to quantitatively examine the relationships between brain anatomy, disease progression, treatment regimens, and genetic influences upon brain structure. Quantifying brain structure ... Full text Link to item Cite

Comparison of antipsychotic medication effects on reducing violence in people with schizophrenia.

Journal Article Br J Psychiatry · July 2008 Featured Publication BACKGROUND: Violence is an uncommon but significant problem associated with schizophrenia. AIMS: To compare antipsychotic medications in reducing violence among patients with schizophrenia over 6 months, identify prospective predictors of violence and exam ... Full text Link to item Cite

The effectiveness of antipsychotic medications in patients who use or avoid illicit substances: results from the CATIE study.

Journal Article Schizophr Res · March 2008 Featured Publication OBJECTIVE: This double-blind study compared a second generation (atypical) antipsychotic drugs compared to a representative older agent for patients with schizophrenia who use or avoid illicit substances. METHODS: Schizophrenic subjects were recruited at 5 ... Full text Link to item Cite

Psychiatric advance directives and reduction of coercive crisis interventions.

Journal Article J Ment Health · January 1, 2008 Featured Publication BACKGROUND: Psychiatric advance directives are intended to enable self-determined treatment for patients who lose decisional capacity, and thus reduce the need for coercive interventions such as police transport, involuntary commitment, seclusion and restr ... Full text Link to item Cite

Characteristics of representative payeeship involving families of beneficiaries with psychiatric disabilities.

Journal Article Psychiatr Serv · November 2007 Featured Publication OBJECTIVE: Although the Social Security Administration frequently assigns family members to serve as representative payees for relatives with psychiatric disabilities, few studies have examined characteristics associated with these payee arrangements or th ... Full text Link to item Cite

EFFECTIVELY IMPLEMENTING PSYCHIATRIC ADVANCE DIRECTIVES TO PROMOTE SELF-DETERMINATION OF TREATMENT AMONG PEOPLE WITH MENTAL ILLNESS.

Journal Article Psychol Public Policy Law · November 2007 Statutes on psychiatric advance directives (PADs) allow competent individuals to document instructions for future mental health treatment in the event of an incapacitating crisis. PADs are aimed at promoting a stronger sense of patient self-determination, ... Full text Link to item Cite

Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study.

Journal Article J Clin Psychiatry · August 2007 Featured Publication OBJECTIVE: Zonisamide and bupropion have been investigated for weight reduction in obese adults. We conducted a preliminary study comparing the effect on body weight of the combination of these 2 drugs versus zonisamide monotherapy. METHOD: This was a 12-w ... Full text Link to item Cite

Competence to complete psychiatric advance directives: effects of facilitated decision making.

Journal Article Law Hum Behav · June 2007 Featured Publication Psychiatric advance directives (PADs) statutes presume competence to complete these documents, but the range and dimensions of decisional competence among people who actually complete PADs is unknown. This study examines clinical and neuropsychological cor ... Full text Link to item Cite

Persistent mild cognitive impairment in geriatric depression.

Journal Article Int Psychogeriatr · February 2007 Featured Publication BACKGROUND: Cognitive impairment often occurs with geriatric depression and impairments may persist despite remission of depression. Although clinical definitions of mild cognitive impairment (MCI) have typically excluded depression, a neuropsychological m ... Full text Link to item Cite

Predictors of workforce turnover in a transported treatment program.

Journal Article Adm Policy Ment Health · January 2007 Featured Publication This study examined relations between workforce turnover and select clinician (demographic and professional characteristics and perceptions of treatment model features and job requirements) organizational (perceptions of organizational climate and structur ... Full text Link to item Cite

Escitalopram treatment of trichotillomania.

Journal Article Int Clin Psychopharmacol · January 2007 With the understanding that serotonergic drugs might curb compulsive hair pulling, we conducted a preliminary investigation examining the effectiveness of escitalopram, a potent and selective serotonin uptake inhibitor, in the treatment of trichotillomania ... Full text Link to item Cite

Facilitated psychiatric advance directives: a randomized trial of an intervention to foster advance treatment planning among persons with severe mental illness.

Journal Article Am J Psychiatry · November 2006 Featured Publication OBJECTIVE: Studies show a high potential demand for psychiatric advance directives but low completion rates. The authors conducted a randomized study of a structured, manualized intervention to facilitate completion of psychiatric advance directives. METHO ... Full text Link to item Cite

Substance use and psychosocial functioning in schizophrenia among new enrollees in the NIMH CATIE study.

Journal Article Psychiatr Serv · August 2006 Featured Publication OBJECTIVE: This study examined the relationship between substance use and psychosocial functioning in schizophrenia. METHODS: Participants were enrolled in the Clinical Antipsychotic Trials of Intervention Effectiveness. This study used baseline assessment ... Full text Link to item Cite

Atomoxetine for weight reduction in obese women: a preliminary randomised controlled trial.

Journal Article Int J Obes (Lond) · July 2006 Featured Publication BACKGROUND AND OBJECTIVE: Atomoxetine is a potent central norepinephrine uptake inhibitor, currently marketed for treatment of attention-deficit/hyperactivity disorder (ADHD). With the understanding that noradrenergic agents could be useful in assisting ob ... Full text Link to item Cite

A national study of violent behavior in persons with schizophrenia.

Journal Article Arch Gen Psychiatry · May 2006 Featured Publication CONTEXT: Violent behavior is uncommon, yet problematic, among schizophrenia patients. The complex effects of clinical, interpersonal, and social-environmental risk factors for violence in this population are poorly understood. OBJECTIVE: To examine the pre ... Full text Link to item Cite

Substance use in persons with schizophrenia: baseline prevalence and correlates from the NIMH CATIE study.

Journal Article J Nerv Ment Dis · March 2006 Featured Publication This study examined baseline correlates of substance use in the NIMH Clinical Antipsychotic Trials of Intervention Effectiveness project. Approximately 60% of the sample was found to use substances, including 37% with current evidence of substance use diso ... Full text Link to item Cite

Ascending Digits Task as a Measure of Executive Function in Geriatric Depression

Journal Article The Journal of Neuropsychiatry and Clinical Neurosciences · February 2006 Full text Cite

A randomized controlled trial of paroxetine for noncardiac chest pain.

Journal Article Psychopharmacol Bull · 2006 Featured Publication Noncardiac chest pain occurs frequently in medical practice and is often difficult to treat. We conducted a randomized double-blind, placebo-controlled, 8-week trial of paroxetine in 50 patients with noncardiac chest pain. None of the patients met criteria ... Link to item Cite

Prefrontal neuropsychological predictors of treatment remission in late-life depression.

Journal Article Neuropsychopharmacology · December 2004 Featured Publication Recent studies suggest that neuropsychological measures involving the prefrontal cortex are associated with treatment remission in late-life depression. To further explore this issue, we studied the neuropsychological performance of 110 depressed individua ... Full text Link to item Cite

Mental health need and access to mental health services by youths involved with child welfare: a national survey.

Journal Article J Am Acad Child Adolesc Psychiatry · August 2004 Featured Publication OBJECTIVE: This study assessed the relationship between the need for and use of mental health services among a nationally representative sample of children who were investigated by child welfare agencies after reported maltreatment. METHOD: Data were colle ... Full text Link to item Cite

Caregiving for persons with mental illness: the impact of outpatient commitment on caregiving strain.

Journal Article J Nerv Ment Dis · August 2004 Featured Publication This study examines factors that contribute to the subjective strain experienced by caregivers of persons with severe mental illness and addresses potential improvement in caregiver strain associated with involuntary outpatient commitment. Subjects from a ... Full text Link to item Cite

Consumers' perceptions of the fairness and effectiveness of mandated community treatment and related pressures.

Journal Article Psychiatr Serv · July 2004 Featured Publication OBJECTIVE: Little research has been conducted on the attitudes of persons with psychiatric disorders toward the potentially adverse or beneficial effects of involuntary outpatient commitment and other forms of mandated community treatment. This study exami ... Full text Link to item Cite

Use of psychotropic medications by youths in therapeutic foster care and group homes.

Journal Article Psychiatr Serv · June 2004 Featured Publication This article examines the use of psychotropic medications among youths in residential community-based placements. Data are from a study funded by the National Institute of Mental Health of therapeutic foster care (June 1999 through May 2001) and group home ... Full text Link to item Cite

Parental arrest and children involved with child welfare services agencies.

Journal Article Am J Orthopsychiatry · April 2004 Featured Publication Data from the National Survey of Child and Adolescent Well-Being show that approximately 1 in 8 (12.5%) children who are subjects of reports of maltreatment investigated by child welfare services (CWS) agencies have parents who were recently arrested. Comp ... Full text Link to item Cite

Characteristics of third-party money management for persons with psychiatric disabilities.

Journal Article Psychiatr Serv · August 2003 Featured Publication OBJECTIVE: The study examined different types of third-party money management arrangements for persons with psychiatric disabilities and consumers' perceptions of their finances in the context of these arrangements. METHODS: Clinical and demographic data w ... Full text Link to item Cite

Assessment of four stakeholder groups' preferences concerning outpatient commitment for persons with schizophrenia.

Journal Article Am J Psychiatry · June 2003 Featured Publication OBJECTIVE: Study findings indicating that involuntary outpatient commitment can improve treatment outcomes among persons with severe mental illness remain controversial. Opponents of outpatient commitment argue that its coerciveness is unacceptable even gi ... Full text Link to item Cite

Zonisamide for weight loss in obese adults: a randomized controlled trial.

Journal Article JAMA · April 9, 2003 Featured Publication CONTEXT: Zonisamide is a marketed antiepileptic drug that has serotonergic and dopaminergic activity in addition to blockade of sodium and calcium channels. Weight loss was an adverse effect associated with zonisamide treatment in epilepsy clinical trials. ... Full text Link to item Cite

Involuntary outpatient commitment and homelessness in persons with severe mental illness.

Journal Article Ment Health Serv Res · March 2003 Featured Publication This study took preliminary steps to explore the relationship between involuntary outpatient commitment (OPC) and the risk of homelessness among individuals with severe mental disorders. Involuntarily hospitalized patients were randomly assigned to be rele ... Full text Link to item Cite

Treatment foster care in a system of care: Sequences and correlates of residential placements

Journal Article Journal of Child and Family Studies · March 1, 2003 We examined Treatment Foster Care (TFC) in residential trajectories for youth with psychiatric disorders and aggressive behavior. We analyzed residential placements of a statewide sample of youth during the 12 months preceding and following admission to TF ... Full text Cite

Psychiatric advance directives: A survey of persons with schizophrenia, family members, and treatment providers

Journal Article International Journal of Forensic Mental Health · January 1, 2003 Psychiatric advance directives (PADs) allow competent persons to request or refuse specific types of treatment and designate a proxy decisionmaker in advance of a mental health crisis when they may lose capacity to make reliable healthcare decisions. A sur ... Full text Cite

Effects of involuntary outpatient commitment on subjective quality of life in persons with severe mental illness.

Journal Article Behav Sci Law · 2003 Featured Publication Recent evidence suggests that involuntary outpatient commitment (OPC), when appropriately applied, can improve adherence with psychiatric treatment, decrease hospital recidivism and arrests, and lower the risk of violent behavior in persons with severe men ... Full text Link to item Cite

Does involuntary outpatient commitment lead to more intensive treatment?

Journal Article Psychol Public Policy Law · 2003 Featured Publication Studies of involuntary outpatient commitment (OPC) among persons with severe mental illness have concluded that OPC is only effective in improving treatment outcomes when it is sustained for 6 months or longer and is combined with frequent outpatient servi ... Full text Link to item Cite

The social-environmental context of violent behavior in persons treated for severe mental illness.

Journal Article Am J Public Health · September 2002 Featured Publication OBJECTIVES: This study examined the prevalence and correlates of violent behavior by individuals with severe mental illness. METHODS: Participants (N = 802) were adults with psychotic or major mood disorders receiving inpatient or outpatient services in pu ... Full text Link to item Cite

Impact of outpatient commitment on victimization of people with severe mental illness.

Journal Article Am J Psychiatry · August 2002 Featured Publication OBJECTIVE: The authors' goal was to evaluate the effectiveness of outpatient commitment in reducing victimization among people with severe mental illness. METHOD: One hundred eighty-four involuntarily hospitalized patients were randomly assigned to be rele ... Full text Link to item Cite

Structural changes as measured by diffusion tensor imaging in late-life depression.

Journal Article AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY · March 1, 2002 Link to item Cite

Hippocampal Volume and Incident Dementia in Geriatric Depression

Journal Article American Journal of Geriatric Psychiatry · February 1, 2002 Full text Cite

Hippocampal volume and incident dementia in geriatric depression.

Journal Article Am J Geriatr Psychiatry · 2002 Featured Publication The authors investigated the role of baseline hippocampal volume on later clinical emergence of dementia in a group of older, non-demented depressed individuals. Subjects were 115 depressed, non-demented participants in a mental health clinical research ce ... Link to item Cite

The perceived coerciveness of involuntary outpatient commitment: findings from an experimental study.

Journal Article J Am Acad Psychiatry Law · 2002 Featured Publication This study examines self-reported coercion in subjects with severe mental illness who were randomly assigned in an experimental study to continue under, or be released from, involuntary outpatient commitment (OPC) subsequent to hospital discharge. After re ... Link to item Cite

Greater depression severity associated with less improvement in depression-associated cognitive deficits in older subjects.

Journal Article Am J Geriatr Psychiatry · 2002 Featured Publication OBJECTIVES: Elderly depressed patients often exhibit cognitive deficits, which may improve with drug therapy. The authors investigated the relationship of baseline depression severity and cognitive improvement with antidepressant treatment in depressed pat ... Link to item Cite

Sociodemographic and clinical predictors of mortality in geriatric depression.

Journal Article Am J Geriatr Psychiatry · 2002 OBJECTIVE: It is well documented that depression and early mortality are related, and current research suggests that depression may influence vascular causes of death. The authors report on prospectively observed mortality in elderly depressed patients, co ... Link to item Cite

Parental incarceration among adolescents receiving mental health services

Journal Article Journal of Child and Family Studies · January 1, 2002 The Bureau of Justice Statistics estimates that approximately 1 in every 50 youth in the U.S. had a parent in State or Federal prison in 1999. Studies of children of incarcerated parents suggest that these youth are at risk for experiencing emotional and b ... Full text Cite

Effects of involuntary outpatient commitment and depot antipsychotics on treatment adherence in persons with severe mental illness.

Journal Article J Nerv Ment Dis · September 2001 Featured Publication This study examines potential improvement in treatment adherence during a study of involuntary outpatient commitment among individuals with severe mental illnesses. Involuntarily hospitalized subjects, awaiting discharge under outpatient commitment, were r ... Full text Link to item Cite

Performance feedback deficit in geriatric depression.

Journal Article Biol Psychiatry · September 1, 2001 Featured Publication BACKGROUND: The orbital frontal cortex is involved with processing of performance feedback. This study tests the hypothesis that older depressed subjects, compared with elderly control subjects, commit more subsequent errors after receiving feedback from a ... Full text Link to item Cite

Bupropion for weight loss: an investigation of efficacy and tolerability in overweight and obese women.

Journal Article Obes Res · September 2001 Featured Publication OBJECTIVE: On the basis of the clinical observations that bupropion facilitated weight loss, we investigated the efficacy and tolerability of this drug in overweight and obese adult women. RESEARCH METHODS AND PROCEDURES: A total of 50 overweight and obese ... Full text Link to item Cite

Evidence of white matter tract disruption in MRI hyperintensities.

Journal Article Biol Psychiatry · August 1, 2001 Featured Publication BACKGROUND: Diffusion tensor imaging (DTI) of brain tissue measures the apparent diffusion coefficient (ADC), or isotropic diffusion, and anisotropy, or diffusion as influenced by tissue structure. We hypothesized that hyperintensities, when compared with ... Full text Link to item Cite

Dr. Swartz and Colleagues Reply

Journal Article American Journal of Psychiatry · April 1, 2001 Full text Cite

A randomized controlled trial of outpatient commitment in North Carolina.

Journal Article Psychiatr Serv · March 2001 Featured Publication OBJECTIVE: A randomized controlled trial of outpatient commitment was conducted in North Carolina to provide empirical data on involuntary outpatient commitment and to evaluate its effectiveness in improving outcomes among persons with severe mental illnes ... Full text Link to item Cite

Severity of subcortical gray matter hyperintensity predicts ECT response in geriatric depression.

Journal Article J ECT · March 2001 Featured Publication OBJECTIVE: To determine the effect of subcortical white and gray matter lesions on ECT outcome. METHOD: 41 geriatric psychiatric inpatients underwent an MRI scan during their ECT work-up. Periventricular, deep white matter, and subcortical gray matter hype ... Full text Link to item Cite

Informant-rated cognitive symptoms in normal aging, mild cognitive impairment, and dementia. Initial development of an informant-rated screen (Brief Cognitive Scale) for mild cognitive impairment and dementia.

Journal Article Psychopharmacol Bull · 2001 Featured Publication An informant-rated cognitive screen may have the potential to reliably help detect early dementia. A valuable scale should have good interitem associations and strong reliability when tested in groups with and without cognitive impairment. Our scale, the B ... Link to item Cite

Victimization: a link between mental illness and violence?

Journal Article Int J Law Psychiatry · 2001 Featured Publication Full text Link to item Cite

Minor depression in family practice: functional morbidity, co-morbidity, service utilization and outcomes.

Journal Article Psychol Med · November 2000 Featured Publication BACKGROUND: Minor depression is a disabling condition commonly seen in primary care settings. Although considerable impairment is associated with minor depression, little is known about the course of the illness. Using a variety of clinical and functional ... Full text Link to item Cite

Randomized trial of sertraline in patients with unexplained chest pain of noncardiac origin.

Journal Article Am Heart J · September 2000 Featured Publication BACKGROUND: Between 10% and 30% of patients with symptoms similar to angina and sufficient to justify cardiac catheterization are found to have normal coronary angiograms. Treatment of patients with chest pain with no apparent cardiac cause is a major clin ... Full text Link to item Cite

Involuntary out-patient commitment and reduction of violent behaviour in persons with severe mental illness.

Journal Article Br J Psychiatry · April 2000 Featured Publication BACKGROUND: Violent behaviour among persons with severe mental illness (SMI) causes public concern and is associated with illness relapse, hospital recidivism and poor outcomes in community-based treatment. AIMS: To test whether involuntary out-patient com ... Full text Link to item Cite

General medical and specialty mental health service use for major depression.

Journal Article Int J Psychiatry Med · 2000 OBJECTIVE: While major depression is common, many depressed persons receive, at best, inadequate treatment. A first step in remedying inadequate detection and treatment of major depression requires understanding the pathways into treatment-from situations ... Full text Link to item Cite

Can involuntary outpatient commitment reduce hospital recidivism?: Findings from a randomized trial with severely mentally ill individuals.

Journal Article Am J Psychiatry · December 1999 Featured Publication OBJECTIVE: The goal of this study was to evaluate the effectiveness of involuntary outpatient commitment in reducing rehospitalizations among individuals with severe mental illnesses. METHOD: Subjects who were hospitalized involuntarily were randomly assig ... Full text Link to item Cite

Consumer perceptions of involuntary outpatient commitment.

Journal Article Psychiatr Serv · November 1999 This study examined beliefs about the provisions of outpatient commitment and their effects among 306 people with severe and persistent mental illness who were awaiting a period of outpatient commitment. More than 80 percent of the respondents perceived th ... Full text Link to item Cite

Assertive community treatment for people with severe mental illness: the effect on hospital use and costs.

Journal Article Health Serv Res · June 1999 Featured Publication OBJECTIVE: To determine the effect of the Program for Assertive Community Treatment (PACT) model on psychiatric inpatient service use in a population of non-emergency psychiatric patients with severe chronic mental illness, and to test for variations in th ... Link to item Cite

Medication Compliance

Journal Article Psychiatric Services · April 1999 Full text Cite

Medication compliance.

Journal Article Psychiatr Serv · April 1999 Full text Link to item Cite

Does a coexisting anxiety disorder predict persistence of depressive illness in primary care patients with major depression?

Journal Article Gen Hosp Psychiatry · 1999 Featured Publication We assessed whether a coexisting anxiety disorder predicts risk for persistent depression in primary care patients with major depression at baseline. Patients with major depression were identified in a 12-month prospective cohort study at a University-base ... Full text Link to item Cite

Criminal victimization of persons with severe mental illness.

Journal Article Psychiatr Serv · January 1999 Featured Publication OBJECTIVE: The types and amounts of crime experienced by persons with severe mental illness were examined to better understand criminal victimization in this population. METHODS: Subjects were 331 involuntarily admitted psychiatric inpatients who were orde ... Full text Link to item Cite

Psychiatric impairment, social contact, and violent behavior: evidence from a study of outpatient-committed persons with severe mental disorder.

Journal Article Soc Psychiatry Psychiatr Epidemiol · December 1998 The need to better understand and manage risk of violent behavior among people with severe mental illness in community care settings is increasingly being recognized, as public-sector mental health systems face mandates to provide more cost-effective servi ... Full text Link to item Cite

Taking the wrong drugs: the role of substance abuse and medication noncompliance in violence among severely mentally ill individuals.

Journal Article Soc Psychiatry Psychiatr Epidemiol · December 1998 Increasing numbers of severely mentally ill individuals are being treated in nonhospital, community-based settings and public concern about potential violence by these individuals has increased, often as a result of tragic, albeit uncommon events. The pres ... Full text Link to item Cite

Male-female differences in the setting and construction of violence among people with severe mental illness.

Journal Article Soc Psychiatry Psychiatr Epidemiol · December 1998 Featured Publication Data from a sample of severely and persistently mentally ill involuntary patients indicated that differences in violence between males and females in the 4 months prior to hospital admission depended on the measure. In the bivariate analysis, males had a g ... Full text Link to item Cite

Administrative update: utilization of services. I. Comparing use of public and private mental health services: the enduring barriers of race and age.

Journal Article Community Ment Health J · April 1998 Featured Publication Data from the NIMH-Epidemiologic Catchment Area Project were used to predict differential use of private versus public outpatient mental health services, a salient concern in integrating public and private services in market-based health care reform effort ... Full text Link to item Cite

Violence and severe mental illness: the effects of substance abuse and nonadherence to medication.

Journal Article Am J Psychiatry · February 1998 Featured Publication OBJECTIVE: Violent behavior among individuals with severe mental illness has become an important focus in community-based care. This study examines the joint effect of substance abuse and medication noncompliance on the greater risk of serious violence amo ... Full text Link to item Cite

The ethical challenges of a randomized controlled trial of involuntary outpatient commitment

Journal Article Journal of Mental Health Administration · September 11, 1997 Involuntary outpatient commitment (OPC) is a civil justice procedure intended to enhance compliance with community mental health treatment, to improve functioning and to reduce recurrent dangerousness and hospital recidivism. The research literature on OPC ... Cite

Violence and severe mental disorder in clinical and community populations: the effects of psychotic symptoms, comorbidity, and lack of treatment.

Journal Article Psychiatry · 1997 This paper examines links between violent behavior, type and severity of psychopathology, substance abuse comorbidity, and community mental health treatment, using matched data from two surveys: the National Institute of Mental Health Epidemiologic Catchme ... Full text Link to item Cite

Interpreting the effectiveness of involuntary outpatient commitment: a conceptual model.

Journal Article J Am Acad Psychiatry Law · 1997 Featured Publication Many experimental trials of community mental health interventions fail to develop testable conceptual models of the specific mechanisms and pathways by which relevant outcomes may occur, thus falling short of usefully interpreting what happens inside the e ... Link to item Cite

Patient perceptions of coercion in mental hospital admission.

Journal Article Int J Law Psychiatry · 1997 Featured Publication Full text Link to item Cite

The ethical challenges of a randomized controlled trial of involuntary outpatient commitment.

Journal Article J Ment Health Adm · 1997 Featured Publication Involuntary outpatient commitment (OPC) is a civil justice procedure intended to enhance compliance with community mental health treatment, to improve functioning, and to reduce recurrent dangerousness and hospital recidivism. The research literature on OP ... Full text Link to item Cite

New directions in research on involuntary outpatient commitment.

Journal Article Psychiatr Serv · April 1995 Featured Publication OBJECTIVE: Involuntary outpatient commitment has been used as a method of improving tenure in community programs for individuals with severe and persistent mental illness. This paper reviews literature on research about involuntary outpatient commitment an ... Full text Link to item Cite

The relationship between insurance coverage and psychiatric disorder in predicting use of mental health services.

Journal Article Am J Psychiatry · December 1994 Featured Publication OBJECTIVE: This study investigated how insurance coverage for mental health services affects outpatient mental health service utilization among those with and among those without a DSM-III psychiatric diagnosis. The authors used a representative community ... Full text Link to item Cite

Mental health service use by the elderly in nursing homes.

Journal Article Am J Public Health · March 1993 Featured Publication OBJECTIVES: Because current Omnibus Budget Reconciliation Act regulations influence the disposition of US nursing home residents who have mental illness, National Nursing Home Survey (1985) data are analyzed for predictors of mental health service use. MET ... Full text Link to item Cite

Reserpine-induced up-regulation of dopamine D2 receptors in the rat striatum is enhanced by denervation but not by chronic receptor blockade.

Journal Article Neurosci Lett · October 8, 1986 Featured Publication Compensatory increases in the density of dopamine (DA) D2 receptors in the rat striatum occur following chronic interruption of dopaminergic neurotransmission. Substantia nigra lesions, DA depletion with reserpine and D2 receptor blockade by neuroleptics i ... Full text Link to item Cite

Clonazepam-induced up-regulation of serotonin1 and serotonin2 binding sites in rat frontal cortex.

Journal Article Adv Neurol · 1986 Featured Publication Chronic administration of the benzodiazepine clonazepam increased the number of [3H]5-HT (5-HT1) and [3H]SPIP (5-HT2) binding sites in rat frontal cortex. In each instance, binding changes reflected increases in the maximum densities of binding sites (Bmax ... Link to item Cite

The effects of chronic bromocriptine treatment on behaviour and dopamine receptor binding in the rat striatum.

Journal Article Eur J Pharmacol · November 26, 1985 Featured Publication Agonist-induced rotation and striatal binding of [3H]spiperone ([3H]SPIP) were assessed in rats with unilateral lesions of the substantia nigra during and after a period of chronic bromocriptine administration. Agonist-induced rotation significantly increa ... Full text Link to item Cite

Presynaptic inhibition of dopamine synthesis in rat striatum: effects of chronic dopamine depletion and receptor blockade.

Journal Article Brain Res · November 18, 1985 Featured Publication These studies assessed the effects of dopamine (DA) depletion and receptor blockade on presynaptic inhibition of DA synthesis in the rat striatum. Chronic reserpine administration significantly decreased striatal DA levels but did not affect in vivo tyrosi ... Full text Link to item Cite

Clonazepam-induced up-regulation of serotonin1 binding sites in frontal cortex of rat.

Journal Article Neuropharmacology · October 1985 Featured Publication Chronic administration of the benzodiazepine, clonazepam, increased the number of [3H]5-hydroxytryptamine (5-HT1) binding sites in the frontal cortex of the rat. The increase reflected a change in the maximum density of binding sites (Bmax) with no change ... Full text Link to item Cite

Chronic levodopa or pergolide administration induces down-regulation of dopamine receptors in denervated striatum.

Journal Article Neurology · September 1984 Featured Publication Refractory response to dopamine (DA) agonists is a common problem in the treatment of Parkinson's disease. In rats with unilateral lesions of the substantia nigra, denervation induced significant increases in striatal 3(H)-spiperone binding sites ipsilater ... Full text Link to item Cite

Biochemical and behavioral evaluation of pergolide as a dopamine agonist in the rat brain.

Journal Article Neuropharmacology · March 1984 Featured Publication The ergot derivative pergolide was evaluated as a dopamine agonist using various behavioral and biochemical analyses. Spontaneous motor activity was decreased by small doses (0.1 mg/kg) of pergolide and increased with larger doses (above 0.5 mg/kg). Hyperm ... Full text Link to item Cite

Electroconvulsive treatment and haloperidol: effects on pre- and postsynaptic dopamine receptors in rat brain.

Journal Article Psychopharmacology (Berl) · 1984 Featured Publication Electroconvulsive treatment (ECT) has a transitory beneficial effect on patients with Parkinson's disease (PD). The possibility that this effect is mediated by dopamine (DA) receptors was investigated in the rat brain. Repeated ECT or chronic haloperidol t ... Full text Link to item Cite

Neurotensin interacts with dopaminergic neurons in rat brain.

Journal Article Peptides · 1983 Featured Publication Neurotensin (NT) injected intracerebroventricularly in rat increases dopamine (DA) turnover in the corpus striatum and nucleus accumbens. Significant increases in 3,4-dihydroxyphenylacetic acid (DOPAC) levels occurred within 15 minutes after injection with ... Full text Link to item Cite

Chlorpromazine methiodide-induced barrel rotation: an antimuscarinic effect.

Journal Article Brain Res · October 28, 1982 Featured Publication Barrel rotation is a motor response observed in rats in which the animal twists about its long axis and rolls laterally. This response was first described following intracerebroventricular injection of somatostatin. The pharmacologic specificity of the res ... Full text Link to item Cite

The effect of chronic L-dopa administration on supersensitive pre- and postsynaptic dopaminergic receptors in rat brain.

Journal Article Life Sci · July 5, 1982 Featured Publication Chronic administration of haloperidol induced supersensitivity of the pre- and postsynaptic dopaminergic receptors in rat brain. The response of the presynaptic receptors was determined by an enhanced inhibitory effect of apomorphine on dopamine synthesis ... Full text Link to item Cite

Evaluation of two new dopamine agonists

Journal Article Neurology · January 1, 1982 Cite

THE EFFECT OF NEUROTENSIN ON DOPAMINERGIC NEURONS IN RAT BRAIN

Journal Article Annals of the New York Academy of Sciences · January 1, 1982 Full text Cite

EVALUATION OF 2 NEW DOPAMINE AGONISTS

Conference NEUROLOGY · 1982 Cite

beta-Adrenergic receptor regulation by agonists and membrane depolarization in rat brain slices.

Journal Article Proc Natl Acad Sci U S A · April 1979 Featured Publication Rat cerebral cortex slices exposed to (-)-isoproterenol and then washed accumulated significantly less cyclic AMP when rechallenged with isoproterenol than did control slices. The isoproterenol-induced desensitization was associated with a concurrent reduc ... Full text Link to item Cite

Histamine-, norepinephrine-, and dopamine-sensitive central adenylate cyclases: effects of chlorpromazine derivatives and butaclamol.

Journal Article Arch Int Pharmacodyn Ther · June 1978 Featured Publication A series of recently available derivatives (quaternary and hydroxylated) of chlorpromazine (CPZ) and butaclamol were evaluated with respect to antagonism of norepinephrine- (NE) (rat cerebral cortex), dopamine- (DA) (rat striatum) and histamine- (H) sensit ... Link to item Cite

The applicability of inescapable shock as a source of animal depression.

Journal Article J Gen Psychol · April 1977 Featured Publication Male rats (N = 27) were given initial experience with escapable shock, equivalent amounts of inescapable shock, or no shock. Measures were then obtained in the ensuing 15 hours on food intake, water intake, number of cage crossings, and weight change for a ... Full text Link to item Cite

Dopamine-sensitive adenylate cyclase: antagonism by impiramine and its analogues.

Journal Article Res Commun Chem Pathol Pharmacol · March 1977 Featured Publication Link to item Cite

Rapid changes in brain beta adrenergic receptors

Journal Article Neurology · January 1, 1977 Cite

Histamine-stimulated adenylate cyclase: blockade by imipramine and its analogues.

Journal Article Commun Psychopharmacol · 1977 Featured Publication Link to item Cite

SUPERSENSITIVITY OF STRIATAL AND CORTICAL ADENYLATE-CYCLASE FOLLOWING RESERPINE - LACK OF EFFECT OF CHRONIC HALOPERIDOL

Journal Article RESEARCH COMMUNICATIONS IN PSYCHOLOGY PSYCHIATRY AND BEHAVIOR · January 1, 1976 Link to item Cite

Suppression of cortical epileptiform activity by generalized and localized ECoG desynchronization.

Journal Article Electroencephalogr Clin Neurophysiol · November 1975 The effects of high frequency electrical stimulation of both diffusely projecting brain regions and regions of more restricted projection were studied on penicillin-induced cortical epileptiform focal activity in the cat. Results obtained were contingent o ... Full text Link to item Cite