Book · February 15, 2025
Non-sewered sanitation systems (NSSS) treat human waste where it is generated, eliminating the need to transport it through sewers. They offer exciting opportunities for safely managed sanitation across the globe. Informed by the extensive experience of te ...
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Journal ArticleNeurogastroenterol Motil · January 2025
BACKGROUND: Patients' report of bowel movement consistency is unreliable. We demonstrate the feasibility of long-term automated stool image data collection using a novel Smart Toilet and evaluate a deterministic computer-vision analytic approach to assess ...
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Journal ArticleJournal of Water Sanitation and Hygiene for Development · September 1, 2024
Understanding user behavior is critical to the adoption of technology; however, there is a paucity of data related to gender-specific sanitation practices and water-use patterns in toilet use despite the global imperative to increase attention toward the n ...
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Journal ArticleWater science and technology : a journal of the International Association on Water Pollution Research · December 2023
Raw wastewater analysis is an important step in treatment assessment; however, it is associated with risks of personnel exposure to pathogens. Such risks are enhanced during virus outbreaks, such as the COVID pandemic, and heat-treatment is a commonly used ...
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Journal ArticleEnvironmental Science Water Research and Technology · November 13, 2023
The long-term performance of an anaerobic bioreactor combined with electrochemical oxidation and integrated into a self-contained public bathroom under daily use was investigated over 14 months in Coimbatore (Tamil Nadu, India). With varying daily number o ...
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Journal ArticleNature Water · November 1, 2023
The toilet could evolve from an unassuming household plumbing fixture to a critical engineering node for onsite wastewater treatment and reuse. ...
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Journal ArticleIEEE Internet of Things Journal · March 1, 2023
Gastrointestinal (GI) conditions are widespread and significantly impact the quality of life and healthcare. Stool appearance is a valuable GI diagnostic indicator, and with the advent of the Internet of Things (IoT), daily monitoring of excreta from a toi ...
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Journal ArticleThe Science of the total environment · January 2023
Urine diversion in a No-Mix Toilet is a promising approach for sustainable fertilizers and reduction of the nutrient load for wastewater treatment; however, user adoption remains a challenge. This study evaluates the Urine Trap, a passive No-Mix toilet des ...
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Journal ArticleThe Science of the total environment · August 2022
Wastewater-based SARS-CoV-2 surveillance on college campuses has the ability to detect individual clinical COVID-19 cases at the building-level. High concordance of wastewater results and clinical cases has been observed when calculated over a time window ...
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Journal ArticleSci Rep · June 27, 2022
Analysis of stool offers simple, non-invasive monitoring for many gastrointestinal (GI) diseases and access to the gut microbiome, however adherence to stool sampling protocols remains a major challenge because of the prevalent dislike of handling one's fe ...
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Journal ArticleJournal of Water Sanitation and Hygiene for Development · May 1, 2021
Onsite incinerators offer a promising solution to the challenges of menstrual waste disposal, particularly in institutional settings. However, thermochemical processes are well known to depend on the nature of the feedstocks and their moisture content (MC) ...
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Journal ArticleWater environment research : a research publication of the Water Environment Federation · January 2021
Electrolysis of blackwater for disinfection and nutrient removal is a portable and scalable technology that can lessen the need for cities to construct large-scale wastewater treatment infrastructure and enable the safe onsite reuse of blackwater. Several ...
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Journal ArticleEnvironmental health insights · January 2021
Due to the increasing adoption of nutrient discharge regulations, many research groups are stepping into new territory with phosphorus (P) measurements. Accurate reporting of P concentrations in effluent from novel wastewater treatment technologies is crit ...
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ConferenceProceedings of Machine Learning Research · January 1, 2021
Precision health monitoring is facilitated by long-term data collection that establishes a health baseline and enables the detection of deviations from it. With the advent of the Internet of Things, monitoring of daily excreta from a toilet is emerging as ...
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Journal ArticleThe Journal of head trauma rehabilitation · September 2020
ObjectiveTo determine the feasibility of short-term cardiovascular responses to postural change as a screening tool for mild traumatic brain injury (mTBI), using heart rate metrics that can be measured with a wearable electrocardiogram sensor. ...
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Journal ArticleThe Science of the total environment · August 2020
A challenge in water reuse for toilet flushing in India and other Asian countries derives from pour flushing practices. It is a common assumption that the amount of pour flushed water used for personal cleansing is small in comparison to the cistern flush ...
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Journal ArticleIEEE transactions on biomedical circuits and systems · August 2020
There is an unmet need for a low-cost instrumented technology for detecting sanitation-related malodor as an alert for maintenance around shared toilets and emerging technologies for onsite waste treatment. In this article, our approach to an electronic no ...
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Journal ArticleSensors (Basel, Switzerland) · May 2020
Technology innovation in sanitation is needed for the 4.2 billion people worldwide, lacking safely managed sanitation services. A major requirement for the adoption of these technologies is the management of malodor around toilet and treatment systems. The ...
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Journal ArticleEnvironmental Science Water Research and Technology · May 1, 2020
The Closed Loop Advanced Sanitation System (CLASS) was designed to treat, disinfect, and recycle toilet blackwater from existing flush toilets in a multi-story apartment building. Two systems were tested at two unique sites in Coimbatore, India for a combi ...
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Journal ArticleThe Science of the total environment · April 2020
4.2 billion people live without access to safely managed sanitation services. This report describes the field testing of an onsite prototype system designed to treat blackwater from a single flush toilet and reuse of the treated effluent for flushing. The ...
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Journal ArticleThe Science of the total environment · February 2020
Innovations that enable cost-effective and resource-conserving treatment of human waste are required for the 4.2 billion people in the world who currently lack safe and reliable sanitation services. Onsite treatment and reuse of blackwater is one strategy ...
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Journal ArticleGates Open Research · January 1, 2020
Background: Transformative sanitation technologies aim to treat fecal sludge (FS) by thermal processes and recover resources from it. There is a paucity of data describing the relevant properties of FS as viable feedstock for thermal treatment in major geo ...
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ConferenceBiocas 2019 Biomedical Circuits and Systems Conference Proceedings · October 1, 2019
There is an unmet need for a low-cost instrumented technology for detecting malodor around toilets and emerging sanitation technologies for onsite waste treatment. Our approach to an electronic nose for sanitation-related malodor is based on the use of ele ...
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Journal ArticleBiological psychology · March 2019
One of the core diagnostic features of autism spectrum disorder (ASD) is engagement in stereotypical motor movements, although the etiology of this repetitive behavior is unknown. Since the 1960s, it has been hypothesized that stereotypical motor movements ...
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Journal ArticleJournal of autism and developmental disorders · May 2018
Repetitive sensory motor behaviors are a direct target for clinical treatment and a potential treatment endpoint for individuals with intellectual or developmental disabilities. By removing the burden associated with video annotation or direct observation, ...
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Journal ArticleJournal of the American Society for Mass Spectrometry · February 2018
Despite many potential applications, miniature mass spectrometers have had limited adoption in the field due to the tradeoff between throughput and resolution that limits their performance relative to laboratory instruments. Recently, a solution to this tr ...
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Journal ArticleJournal of water and health · February 2018
Water quality and sanitation are inextricably linked to prevalence and control of soil-transmitted helminth infections, a public health concern in resource-limited settings. India bears a large burden of disease associated with poor sanitation. Transformat ...
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Journal ArticleInternational Journal of Mass Spectrometry · November 1, 2017
The use of microelectromechanical systems (MEMS) components in miniature mass spectrometers is particularly attractive due to their small size and scalable manufacturing capability. Our group has pioneered the development of miniature electron ionization s ...
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Journal ArticleAlternatives to laboratory animals : ATLA · July 2017
In 2009, the passing of the Family Smoking Prevention and Tobacco Control Act facilitated the establishment of the FDA Center for Tobacco Products (CTP), and gave it regulatory authority over the marketing, manufacture and distribution of tobacco products, ...
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ConferenceALTEX · January 2017
Translating in vitro biological data into actionable information related to human health holds the potential to improve disease treatment and risk assessment of chemical exposures. While genomics has identified regulatory pathways at the cellular level, tr ...
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Journal ArticleBiomicrofluidics · November 2015
We report a microfluidic blood-brain barrier model that enables both physiological shear stress and optical transparency throughout the device. Brain endothelial cells grown in an optically transparent membrane-integrated microfluidic device were able to w ...
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Journal ArticleToxicology and applied pharmacology · October 2015
Microelectrode arrays (MEAs) recording extracellular field potentials of human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CM) provide a rich data set for functional assessment of drug response. The aim of this work is the development of a m ...
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Journal ArticleBrain research · May 2015
Blood-brain barrier (BBB) function is regulated by dynamic interactions among cell types within the neurovascular unit, including astrocytes and endothelial cells. Co-culture models of the BBB typically involve astrocytes seeded on two-dimensional (2D) sur ...
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Journal ArticleLab on a chip · September 2014
Microfluidic cell cultures enable investigation of complex physiological tissue properties and functionalities. For convenience, they are often implemented with immortalized cell lines, but primary cells more closely approximate the in vivo biology. Our ai ...
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Journal ArticleProceedings of the National Academy of Sciences of the United States of America · October 2013
Severe acute respiratory syndrome with high mortality rates (~50%) is associated with a novel group 2c betacoronavirus designated Middle East respiratory syndrome coronavirus (MERS-CoV). We synthesized a panel of contiguous cDNAs that spanned the entire ge ...
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Journal ArticleBiomicrofluidics · September 6, 2013
A versatile method to fabricate a multilayer polydimethylsiloxane (PDMS) device with micropillar arrays within the inner layer is reported. The method includes an inexpensive but repeatable approach for PDMS lamination at high compressive force to achieve ...
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Journal ArticleIEEE Transactions on Nanotechnology · July 17, 2012
We demonstrate a postgrowth in situ chlorine passivation method for suppressing surface-dominant transport in Si nanowires (SiNWs). This scheme helps avoid misorientations and meandering while facilitating the passivation of surface states. The leakage cur ...
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Journal ArticleSensors and Actuators A Physical · May 1, 2012
The electromechanical performance of piezoelectric scanning mirrors for endoscopy imaging is presented. The devices are supported by a single actuating cantilever to achieve a high fill factor, the ratio of mirror area to the combined mirror and actuator a ...
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Journal ArticleSensors and Actuators B Chemical · January 3, 2012
The design, fabrication and characterization of a compact optical biosensor based on an input grating coupler are presented. The sensor device consists of a waveguide-integrated single grating structure. The optical reader is based on the use of a largely ...
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Journal ArticleApplied Physics A Materials Science and Processing · November 1, 2011
We demonstrate bridged nanowires on a non-single-crystal substrate as a versatile fabrication approach to combine active and passive photonic functionalities on silicon platforms. Silicon nanowires are grown on vertical non-single-crystal surfaces by a vap ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · July 6, 2011
The TWIST platform is an optical evanescent wave sensor which enables a label-free immunoassay-based portable instrument. The approach is based on input grating coupler sensors serving as functionalized sensing devices. Binding of the target analyte to the ...
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Journal ArticleIEEE Journal on Selected Topics in Quantum Electronics · July 1, 2011
One-dimensional semiconductor nanostructures (nanowires (NWs), nanotubes, nanopillars, nanorods, etc.) based photodetectors (PDs) have been gaining traction in the research community due to their ease of synthesis and unique optical, mechanical, electrical ...
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Journal ArticleBiomicrofluidics · January 1, 2011
The recent development of microfluidic "lab on a chip" devices requiring sample sizes <100 μL has given rise to the need to concentrate dilute samples and trap analytes, especially for surface-based detection techniques. We demonstrate a particle collectio ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · October 26, 2010
We demonstrate a post-growth in-situ chlorine passivation for suppressing surface-dominant transport in Si nanowires (SiNWs). The leakage current of bridged SiNWs suppressed more than five orders of magnitude as a result of chlorine passivation while the s ...
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Journal ArticleMicroelectronic Engineering · January 1, 2010
We demonstrate that a replica grating can be effectively used as an inexpensive stamp for nanoimprint lithography to pattern diffractive optical couplers integrated with planar optical waveguides. Imprinted grating patterns were integrated with silicon oxy ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · November 23, 2009
The growth of crystalline 1D nanowires of semiconductors on non-epitaxial surfaces holds the promise to overcome many of the current challenges of heteroepitaxial material synthesis and device fabrication for a wide range of electronic and photonic applica ...
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Journal ArticleJournal of Micromechanics and Microengineering · November 9, 2009
A novel piezoelectric scanning mirror design for endoscopic optical coherence tomography (OCT) is presented. OCT is an interferometric technique providing microscopic tomographic sectioning of biological samples with mm-range penetration capability in tiss ...
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Journal ArticleDental materials : official publication of the Academy of Dental Materials · September 2009
ObjectiveThe overall goal of this research was to develop a practical method to chemically modify the surface of high strength dental ceramics (i.e. zirconia) to facilitate viable, robust adhesive bonding using commercially available silanes and r ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · June 15, 2009
A planar optical waveguide with an input grating coupler was used as an affinity-based biodetection device. Nanoimprint lithography was used to integrate the grating patterns with low loss silicon oxynitride thin-film waveguides. A widely tunable laser sou ...
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Journal ArticleSensors and Actuators B Chemical · May 14, 2008
A planar optical waveguide with an input grating coupler was used as a label-free biodetection device. Nanoimprint lithography was used to integrate the grating patterns with low loss silicon oxynitride thin film waveguides. A widely tunable laser source a ...
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Journal ArticleThin Solid Films · April 30, 2008
The mechanical and electrical properties of indium tin oxide films on polyethylene naphthalate substrates are critical to the development of flexible displays. In the present study, mechanical and electrical properties are studied as a function of processi ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · November 15, 2007
We have evaluated several methods for generating multi-color emission for IR scene projector applications. The baseline requirements we employed were the ability to simulate color temperatures in the range 300-3000 K, minimum radiance levels consistent wit ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · May 24, 2007
This work focuses on the effects of custom-designed, two-dimensional grating structures on the sensitivity of optical waveguides biosensors in the input grating coupler configuration. Calculations suggest that suitably designed diffractive structures with ...
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Journal ArticleThin Solid Films · April 9, 2007
Mechanical flexing of plastic substrates coated with thin film permeation barriers causes stress-induced cracks that may lead to device degradation. This phenomenon is of particular importance for organic light emitting diodes, an emerging display technolo ...
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ConferenceMaterials Research Society Symposium Proceedings · January 1, 2007
This work investigates the mechanical properties of indium tin oxide deposited on polyethylene napthalate substrates by rf sputtering method as a function of deposition conditions, including rf power, substrate temperature, and substrate treatment. X-ray d ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · August 23, 2006
Grating-based optical waveguide devices offer label-free biodetection capabilities relying on optical response to adsorption of analytes and corresponding changes of refractive index. Various configurations of this measurement approach were explored with t ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · May 25, 2006
Silicon oxynitride optical waveguides with a grating coupler were used for a label-free detection approach that measures the change of refractive index at the grating surface. Two approaches were used for the grating fabrication: (i) commercially available ...
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ConferenceDigest of Technical Papers SID International Symposium · December 1, 2005
We describe a unique micro-display metrology system in which the stage can be rotated arbitrarily and the area of interest does not leave the field of view. Similarly, the sample can be tilted up to 60 degrees and the area of interest stays continuously in ...
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Journal ArticleReview of Scientific Instruments · December 1, 2005
We describe a mechanical configuration that allows any point on a flat sample to be moved to any angle of tilt and rotation (within the limits of which the stage is capable) while maintaining the area of interest at a constant focus and within the field of ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · November 9, 2005
Organic light emitting diode (OLED) based displays are well suited for fabrication on flexible polymer substrates. In order to achieve the vision of a highly flexible, rollable display, significant progress must be made in understanding and overcoming the ...
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Journal ArticleLangmuir · July 5, 2005
We report an electrohydrodynamic effect arising from the application of alternating electric fields to patterned electrode surfaces. The AC fields were applied to dilute suspensions of latex microspheres enclosed between a patterned silicon wafer and an IT ...
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Journal ArticleJournal of the Society for Information Display · July 1, 2005
Two different approaches to automated bend testing of flexible substrates for display applications were implemented and characterized: a conventional collapsing radius geometry and a novel technique called the "X-Y- θ" geometry. Indium tin oxide (ITO) coat ...
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Journal ArticleLangmuir : the ACS journal of surfaces and colloids · May 2005
We investigated the capability of an ordered array of microspheres to act as a template for deposition and ordering of a subsequent layer of microspheres. An evaporation-based technique was used to deposit monolayers of large colloidal spheres. A novel tec ...
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ConferenceConference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS · December 1, 2004
Mechanical flexing of plastic substrates coated with thin film permeation barriers causes sub-micron cracks that lead to device degradation. We demonstrate an improved method to rapidly observe cracks and evaluate mechanical performance of permeation barri ...
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ConferenceProceedings of SPIE - The International Society for Optical Engineering · December 1, 2004
The demonstration of arrays of light guides that are fabricated in sheets and laminated together to form tapered plastic fiber optic bundles is presented. Electrophoretic displays can be used for seamless tiling, but electrophoretic displays are not as mat ...
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Journal ArticleApplied Physics Letters · October 18, 2004
Multilayer indium-tin-oxide (ITO)-Ag-ITO stacks were evaluated as transparent conductors for flexible organic light-emitting diode (OLED) displays. The ITO-metal-ITO (IMI) samples exhibited significantly reduced sheet resistance over ITO and greater than 8 ...
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ConferenceMaterials Research Society Symposium Proceedings · January 1, 2004
We investigated the fabrication of a 3D colloid crystal assembled in a layer-by-layer fashion on a template substrate. This method of assembling an ordered structure offers flexibility in the choice of crystal orientation, because of the template, and the ...
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ConferenceMaterials Research Society Symposium Proceedings · January 1, 2004
The use of brittle materials in flexible displays requires the understanding of the mechanical limitations of the materials and the various display architectures. We discuss various approaches to mechanical bend tests for components of flexible displays an ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · November 26, 2003
A large seamless display that could be set up rapidly, operated effectively, and moved quickly would be a great value to the military. Such a display system would be even more beneficial if it consisted entirely of easily available, commercial, off-the-she ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · August 8, 2003
We have developed a mechanical, optical and digital system based only on commercially available equipment to allow a seamlessly tiled projection display system to be set up and aligned very rapidly. Using a digital camera and motorized projectors, our prot ...
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Journal ArticleAdvanced Materials · May 2, 2003
The photonic crystal composites with reversible high-frequency stop band shifts were studied. Two forms of manipulating spherical colloidal particles for the generation of photonic crystals were used. A report on a procedure that allowed for the tailoring ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · December 1, 2002
Physically robust photonic bandgap (PEG) composites based on electrostatically stabilized polymeric colloidal particles are presented. The glass transition (Tg) of the composites can be varied over a large temperature range through the selection ...
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Journal ArticleBiophysical journal · December 2002
Using optical tweezers and single particle tracking, we have revealed the motion of a single protein, the lambda-receptor, in the outer membrane of living Escherichia coli bacteria. We genetically modified the lambda-receptor placing a biotin on an extrace ...
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Journal ArticleMolecular biology of the cell · October 2002
EB1 targets to polymerizing microtubule ends, where it is favorably positioned to regulate microtubule polymerization and confer molecular recognition of the microtubule end. In this study, we focus on two aspects of the EB1-microtubule interaction: regula ...
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Journal ArticleJournal of Physics B: Atomic, Molecular and Optical Physics · May 14, 2002
The electron transfer reaction Li+ + Na(3p) → Li(2p) + Na+ is studied experimentally and theoretically in the velocity range v = 0.1-0.4 au. The final state manifold as a function of the optical preparation of the initial state is investigated by means of ...
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Journal ArticleJournal of Physics B Atomic Molecular and Optical Physics · May 14, 2002
This paper reports experimental and theoretical P-state-to-P-state results for the electron transfer process Li+ + Na(3p) → Li(2p) + Na+ at an impact energy of 1 keV. By a systematic combination of the optical preparation of specific ...
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Journal ArticleJournal of Physics B Atomic Molecular and Optical Physics · May 14, 2002
We present a parametrization in terms of Stokes parameters for the scattering from a P state to a P state for atomic collisions in a beam experiment. The classic approach to a 'complete scattering experiment', well known for S-state-to-P-state transitions, ...
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Journal ArticleProbe Microscopy · December 1, 2001
A pair of optical tweezers is an eminent tool for manipulating biological specimens at the macromolecular level. Optical tweezers measure corresponding forces and distances typically in the pico Newton and nanometer regim0es. Compared to the Atomic Force M ...
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Journal ArticleBiophysical journal · July 2001
Whether polarized treadmilling is an intrinsic property of microtubules assembled from pure tubulin has been controversial. We have tested this possibility by imaging the polymerization dynamics of individual microtubules in samples assembled to steady-sta ...
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Journal ArticleJournal of Physics B Atomic Molecular and Optical Physics · August 14, 1998
The final state integral alignment for the electron transfer process 6Li+ + Na(3s) → 6Li(2p) + Na+ is investigated in the keV energy range. Experimentally, polarization analysed photons from the Li I 22
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Journal ArticleJournal of Biomedical Optics · January 1, 1997
Emission from a single-mode 100 mW diode laser at 840 nm is used to create optical tweezers: the trapping laser beam is introduced into a microscope and focused by the objective. The microscope also allows monitoring of the motion of the trapped particles. ...
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Journal ArticleOptics Communications · December 15, 1996
A cesium magneto-optical trap operating at a large atomic density in multiple scattering regime has been investigated. The trap operates with a large Rabi frequency for trapping lasers. The atomic number, the dimension of the atomic cloud, the atomic densi ...
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ConferenceProceedings of SPIE the International Society for Optical Engineering · January 1, 1996
Emission from a single mode 100 mW laser diode at 850 nm is used for realizing optical tweezers: the laser beam is introduced into a microscope and focused by the objective into the object plane. Injection of the beam into a 40X microscope objective has be ...
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