Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections.
Publication
, Journal Article
Autmizguine, J; Moran, C; Gonzalez, D; Capparelli, EV; Smith, PB; Grant, GA; Benjamin, DK; Cohen-Wolkowiez, M; Watt, KM
Published in: Pediatr Infect Dis J
October 2014
This study described the cerebrospinal fluid (CSF) exposure of vancomycin in 8 children prescribed intravenous vancomycin therapy for cerebral ventricular shunt infection. Vancomycin CSF concentrations ranged from 0.06 to 9.13 mg/L and the CSF: plasma ratio ranged from 0 to 0.66. Two of 3 children with a staphylococcal CSF infection had CSF concentrations greater than minimal inhibitory concentration at the end of the dosing interval.
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Published In
Pediatr Infect Dis J
DOI
EISSN
1532-0987
Publication Date
October 2014
Volume
33
Issue
10
Start / End Page
e270 / e272
Location
United States
Related Subject Headings
- Vancomycin
- Prospective Studies
- Pediatrics
- Meningitis, Bacterial
- Male
- Infant
- Humans
- Female
- Child, Preschool
- Child
Citation
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Chicago
ICMJE
MLA
NLM
Autmizguine, J., Moran, C., Gonzalez, D., Capparelli, E. V., Smith, P. B., Grant, G. A., … Watt, K. M. (2014). Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections. Pediatr Infect Dis J, 33(10), e270–e272. https://doi.org/10.1097/INF.0000000000000385
Autmizguine, Julie, Cassie Moran, Daniel Gonzalez, Edmund V. Capparelli, P Brian Smith, Gerald A. Grant, Daniel K. Benjamin, Michael Cohen-Wolkowiez, and Kevin M. Watt. “Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections.” Pediatr Infect Dis J 33, no. 10 (October 2014): e270–72. https://doi.org/10.1097/INF.0000000000000385.
Autmizguine J, Moran C, Gonzalez D, Capparelli EV, Smith PB, Grant GA, et al. Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections. Pediatr Infect Dis J. 2014 Oct;33(10):e270–2.
Autmizguine, Julie, et al. “Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections.” Pediatr Infect Dis J, vol. 33, no. 10, Oct. 2014, pp. e270–72. Pubmed, doi:10.1097/INF.0000000000000385.
Autmizguine J, Moran C, Gonzalez D, Capparelli EV, Smith PB, Grant GA, Benjamin DK, Cohen-Wolkowiez M, Watt KM. Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections. Pediatr Infect Dis J. 2014 Oct;33(10):e270–e272.
Published In
Pediatr Infect Dis J
DOI
EISSN
1532-0987
Publication Date
October 2014
Volume
33
Issue
10
Start / End Page
e270 / e272
Location
United States
Related Subject Headings
- Vancomycin
- Prospective Studies
- Pediatrics
- Meningitis, Bacterial
- Male
- Infant
- Humans
- Female
- Child, Preschool
- Child