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FUNCTIONAL OUTCOMES OF YOUNG INFANTS WITH AND WITHOUT MACULAR EDEMA.

Publication ,  Journal Article
Rothman, AL; Tran-Viet, D; Vajzovic, L; Tai, V; Sarin, N; Holgado, S; Gustafson, KE; Cotten, CM; Freedman, SF; Toth, CA
Published in: Retina
October 2015

PURPOSE: The authors relate posterior segment microanatomy from perinatal spectral domain optical coherence tomography to visual acuity, brain abnormalities, and neurodevelopment. METHODS: Thirteen infants (11 preterm and 2 term birth), imaged in the nursery with portable spectral domain optical coherence tomography, had visual acuity and sensorimotor testing at age 9 months to 15 months (grating acuity) or 4 years to 5 years (optotype), and medical records reviewed for brain magnetic resonance imaging reports and Bayley scales testing at age 18 months to 24 months. RESULTS: Eight children with age-appropriate macular microanatomy without edema on perinatal spectral domain optical coherence tomography had optimal (≥ 20/40) or within normal limits (grating acuity) visual acuity. Five children with perinatal macular edema had suboptimal visual acuity (in 9/10 eyes) and sensorimotor deficits, magnetic resonance imaging abnormalities, or poor neurodevelopment. Macular edema persisted in 1 infant through 9-month corrected age. CONCLUSION: Maturation of the visual system and evolution of retinal anomalies can be monitored with posterior segment spectral domain optical coherence tomography. Retinal microanatomy observed in infancy might relate to subsequent vision and other central nervous system events, but additional studies are needed to determine the range of normal microanatomy in infants and how this relates to vision and neurodevelopment.

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Published In

Retina

DOI

EISSN

1539-2864

Publication Date

October 2015

Volume

35

Issue

10

Start / End Page

2018 / 2027

Location

United States

Related Subject Headings

  • Visual Acuity
  • Tomography, Optical Coherence
  • Retina
  • Ophthalmology & Optometry
  • Male
  • Magnetic Resonance Imaging
  • Macular Edema
  • Infant
  • Humans
  • Gestational Age
 

Citation

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Chicago
ICMJE
MLA
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Rothman, A. L., Tran-Viet, D., Vajzovic, L., Tai, V., Sarin, N., Holgado, S., … Toth, C. A. (2015). FUNCTIONAL OUTCOMES OF YOUNG INFANTS WITH AND WITHOUT MACULAR EDEMA. Retina, 35(10), 2018–2027. https://doi.org/10.1097/IAE.0000000000000579
Rothman, Adam L., Du Tran-Viet, Lejla Vajzovic, Vincent Tai, Neeru Sarin, Sandra Holgado, Kathryn E. Gustafson, C Michael Cotten, Sharon F. Freedman, and Cynthia A. Toth. “FUNCTIONAL OUTCOMES OF YOUNG INFANTS WITH AND WITHOUT MACULAR EDEMA.Retina 35, no. 10 (October 2015): 2018–27. https://doi.org/10.1097/IAE.0000000000000579.
Rothman AL, Tran-Viet D, Vajzovic L, Tai V, Sarin N, Holgado S, et al. FUNCTIONAL OUTCOMES OF YOUNG INFANTS WITH AND WITHOUT MACULAR EDEMA. Retina. 2015 Oct;35(10):2018–27.
Rothman, Adam L., et al. “FUNCTIONAL OUTCOMES OF YOUNG INFANTS WITH AND WITHOUT MACULAR EDEMA.Retina, vol. 35, no. 10, Oct. 2015, pp. 2018–27. Pubmed, doi:10.1097/IAE.0000000000000579.
Rothman AL, Tran-Viet D, Vajzovic L, Tai V, Sarin N, Holgado S, Gustafson KE, Cotten CM, Freedman SF, Toth CA. FUNCTIONAL OUTCOMES OF YOUNG INFANTS WITH AND WITHOUT MACULAR EDEMA. Retina. 2015 Oct;35(10):2018–2027.

Published In

Retina

DOI

EISSN

1539-2864

Publication Date

October 2015

Volume

35

Issue

10

Start / End Page

2018 / 2027

Location

United States

Related Subject Headings

  • Visual Acuity
  • Tomography, Optical Coherence
  • Retina
  • Ophthalmology & Optometry
  • Male
  • Magnetic Resonance Imaging
  • Macular Edema
  • Infant
  • Humans
  • Gestational Age