Genetic Susceptibility to Fungal Infections: What is in the Genes?
Publication
, Journal Article
Maskarinec, SA; Johnson, MD; Perfect, JR
Published in: Curr Clin Microbiol Rep
June 2016
The development of severe fungal infections has long been associated with traditional risk factors such as profound immunosuppression, yet it remains challenging to understand why under similar conditions only some patients will develop these infections while others will not. Recent studies have demonstrated the importance of host genetic variation in influencing the severity and susceptibility to invasive fungal infections (IFIs). In this review, we examine selected primary immunodeficiencies characterized by their vulnerability to a narrow range of fungal pathogens, and then focus on recently identified genetic polymorphisms associated with an increased susceptibility to IFIs.
Duke Scholars
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Published In
Curr Clin Microbiol Rep
DOI
ISSN
2196-5471
Publication Date
June 2016
Volume
3
Issue
2
Start / End Page
81 / 91
Location
Switzerland
Citation
APA
Chicago
ICMJE
MLA
NLM
Maskarinec, S. A., Johnson, M. D., & Perfect, J. R. (2016). Genetic Susceptibility to Fungal Infections: What is in the Genes? Curr Clin Microbiol Rep, 3(2), 81–91. https://doi.org/10.1007/s40588-016-0037-3
Maskarinec, Stacey A., Melissa D. Johnson, and John R. Perfect. “Genetic Susceptibility to Fungal Infections: What is in the Genes?” Curr Clin Microbiol Rep 3, no. 2 (June 2016): 81–91. https://doi.org/10.1007/s40588-016-0037-3.
Maskarinec SA, Johnson MD, Perfect JR. Genetic Susceptibility to Fungal Infections: What is in the Genes? Curr Clin Microbiol Rep. 2016 Jun;3(2):81–91.
Maskarinec, Stacey A., et al. “Genetic Susceptibility to Fungal Infections: What is in the Genes?” Curr Clin Microbiol Rep, vol. 3, no. 2, June 2016, pp. 81–91. Pubmed, doi:10.1007/s40588-016-0037-3.
Maskarinec SA, Johnson MD, Perfect JR. Genetic Susceptibility to Fungal Infections: What is in the Genes? Curr Clin Microbiol Rep. 2016 Jun;3(2):81–91.
Published In
Curr Clin Microbiol Rep
DOI
ISSN
2196-5471
Publication Date
June 2016
Volume
3
Issue
2
Start / End Page
81 / 91
Location
Switzerland