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Risk for non-home discharge following surgery for ischemic mitral valve disease.

Publication ,  Journal Article
Lala, A; Chang, HL; Liu, X; Charles, EJ; Yerokun, BA; Bowdish, ME; Thourani, VH; Mack, MJ; Miller, MA; O'Gara, PT; Blackstone, EH; Gelijns, AC ...
Published in: J Thorac Cardiovasc Surg
December 2021

OBJECTIVES: To determine the frequency and risk factors for non-home discharge (NHD) and its association with clinical outcomes and quality of life (QOL) at 1 year following cardiac surgery in patients with ischemic mitral regurgitation (IMR). METHODS: Discharge disposition was evaluated in 552 patients enrolled in trials of severe or moderate IMR. Patient and in-hospital factors associated with NHD were identified using logistic regression. Subsequently, association of NHD with 1-year mortality, serious adverse events (SAEs), and QOL was assessed. RESULTS: NHD was observed in 30% (154/522) with 25% (n = 71/289) in moderate and 36% (n = 83/233) in patients with severe IMR (unadjusted P = .006), a difference not significant after including age (5-year change: adjusted odds ratio [adjOR], 1.52; 95% confidence interval [CI], 1.35-1.72; P < .001), diabetes (adjOR, 1.94; 95% CI, 1.27-2.94; P = .002), and previous heart failure (adjOR, 1.64; 95% CI, 1.06-2.52; P = .03). Odds of NHD were increased for patients with postoperative SAEs (adjOR, 1.85; 95% CI, 1.19-2.86; P = .01) but not based on type of cardiac surgery. Greater rates of death and SAEs were observed in NHD patients at 1 year: adjusted hazard ratio, 4.29 (95% CI, 2.14-8.59; P < .001) and adjusted rate ratio, 1.45 (95% CI, 1.03-2.02; P = .03), respectively. QOL did not differ significantly between groups. CONCLUSIONS: NHD is common following surgery for IMR, influenced by older age, diabetes, previous heart failure, and postoperative SAEs. These patients may be at greater risk of death and subsequent SAEs after discharge. Discussion of NHD with patients may have important implications for decision-making and guiding expectations following cardiac surgery.

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Published In

J Thorac Cardiovasc Surg

DOI

EISSN

1097-685X

Publication Date

December 2021

Volume

162

Issue

6

Start / End Page

1769 / 1778.e7

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Risk Assessment
  • Respiratory System
  • Quality of Life
  • Prospective Studies
  • Patient Discharge
  • Myocardial Ischemia
  • Mitral Valve Insufficiency
  • Middle Aged
 

Citation

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Lala, A., Chang, H. L., Liu, X., Charles, E. J., Yerokun, B. A., Bowdish, M. E., … Cardiothoracic Surgical Trials Network (CTSN) Working Group. (2021). Risk for non-home discharge following surgery for ischemic mitral valve disease. J Thorac Cardiovasc Surg, 162(6), 1769-1778.e7. https://doi.org/10.1016/j.jtcvs.2020.02.084
Lala, Anuradha, Helena L. Chang, Xiaoyu Liu, Eric J. Charles, Babatunde A. Yerokun, Michael E. Bowdish, Vinod H. Thourani, et al. “Risk for non-home discharge following surgery for ischemic mitral valve disease.J Thorac Cardiovasc Surg 162, no. 6 (December 2021): 1769-1778.e7. https://doi.org/10.1016/j.jtcvs.2020.02.084.
Lala A, Chang HL, Liu X, Charles EJ, Yerokun BA, Bowdish ME, et al. Risk for non-home discharge following surgery for ischemic mitral valve disease. J Thorac Cardiovasc Surg. 2021 Dec;162(6):1769-1778.e7.
Lala, Anuradha, et al. “Risk for non-home discharge following surgery for ischemic mitral valve disease.J Thorac Cardiovasc Surg, vol. 162, no. 6, Dec. 2021, pp. 1769-1778.e7. Pubmed, doi:10.1016/j.jtcvs.2020.02.084.
Lala A, Chang HL, Liu X, Charles EJ, Yerokun BA, Bowdish ME, Thourani VH, Mack MJ, Miller MA, O’Gara PT, Blackstone EH, Moskowitz AJ, Gelijns AC, Mullen JC, Stevenson LW, Cardiothoracic Surgical Trials Network (CTSN) Working Group. Risk for non-home discharge following surgery for ischemic mitral valve disease. J Thorac Cardiovasc Surg. 2021 Dec;162(6):1769-1778.e7.
Journal cover image

Published In

J Thorac Cardiovasc Surg

DOI

EISSN

1097-685X

Publication Date

December 2021

Volume

162

Issue

6

Start / End Page

1769 / 1778.e7

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Risk Assessment
  • Respiratory System
  • Quality of Life
  • Prospective Studies
  • Patient Discharge
  • Myocardial Ischemia
  • Mitral Valve Insufficiency
  • Middle Aged