Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.
Publication
, Journal Article
Newman, JD; Douglas, PS; Zhbannikov, I; Ferencik, M; Foldyna, B; Hoffmann, U; Shah, SH; Ginsburg, GS; Lu, MT; Voora, D
Published in: Am Heart J
October 2022
A polygenic risk score (PGS) is associated with obstructive coronary artery disease (CAD) independent of traditional risk factors. Coronary computed tomography angiography (CTA) can characterize coronary plaques, including features of highrisk CAD. However, it is unknown if a PGS is associated with obstructive CAD and high-risk CAD phenotypes in patients with symptoms suggestive of CAD.
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Published In
Am Heart J
DOI
EISSN
1097-6744
Publication Date
October 2022
Volume
252
Start / End Page
12 / 15
Location
United States
Related Subject Headings
- Risk Factors
- Risk Assessment
- Prospective Studies
- Predictive Value of Tests
- Phenotype
- Humans
- Coronary Artery Disease
- Coronary Angiography
- Computed Tomography Angiography
- Chest Pain
Citation
APA
Chicago
ICMJE
MLA
NLM
Newman, J. D., Douglas, P. S., Zhbannikov, I., Ferencik, M., Foldyna, B., Hoffmann, U., … Voora, D. (2022). Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial. Am Heart J, 252, 12–15. https://doi.org/10.1016/j.ahj.2022.05.012
Newman, Jonathan D., Pamela S. Douglas, Ilya Zhbannikov, Maros Ferencik, Borek Foldyna, Udo Hoffmann, Svati H. Shah, Geoffrey S. Ginsburg, Michael T. Lu, and Deepak Voora. “Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.” Am Heart J 252 (October 2022): 12–15. https://doi.org/10.1016/j.ahj.2022.05.012.
Newman JD, Douglas PS, Zhbannikov I, Ferencik M, Foldyna B, Hoffmann U, et al. Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial. Am Heart J. 2022 Oct;252:12–5.
Newman, Jonathan D., et al. “Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial.” Am Heart J, vol. 252, Oct. 2022, pp. 12–15. Pubmed, doi:10.1016/j.ahj.2022.05.012.
Newman JD, Douglas PS, Zhbannikov I, Ferencik M, Foldyna B, Hoffmann U, Shah SH, Ginsburg GS, Lu MT, Voora D. Associations of a polygenic risk score with coronary artery disease phenotypes in the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial. Am Heart J. 2022 Oct;252:12–15.
Published In
Am Heart J
DOI
EISSN
1097-6744
Publication Date
October 2022
Volume
252
Start / End Page
12 / 15
Location
United States
Related Subject Headings
- Risk Factors
- Risk Assessment
- Prospective Studies
- Predictive Value of Tests
- Phenotype
- Humans
- Coronary Artery Disease
- Coronary Angiography
- Computed Tomography Angiography
- Chest Pain