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The Association of Digital Health Application Use With Heart Failure Care and Outcomes: Insights From CONNECT-HF.

Publication ,  Journal Article
Rao, VN; Kaltenbach, LA; Granger, BB; Fonarow, GC; Al-Khalidi, HR; Albert, NM; Butler, J; Allen, LA; Lanfear, DE; Ariely, D; Miller, JM ...
Published in: J Card Fail
October 2022

BACKGROUND: It is unknown whether digital applications can improve guideline-directed medical therapy (GDMT) and outcomes in heart failure with reduced ejection fraction (HFrEF). METHODS AND RESULTS: Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure trial (CONNECT-HF) included an optional, prospective ancillary study of a mobile health application among patients hospitalized due to HFrEF. Digital users were matched to nonusers from the usual-care group. Coprimary outcomes included change in opportunity-based composite HF quality scores and HF rehospitalization or all-cause mortality. Among 2431 patients offered digital applications across the United States, 1526 (63%) had limited digital access or insufficient data, 425 (17%) were digital users, and 480 (20%) declined use. Digital users were similar in age to those who declined use (mean 58 vs 60 years; P = 0.031). Digital users (n = 368) vs matched nonusers (n = 368) had improved composite HF quality scores (48.0% vs 43.6%; + 4.76% [3.27-6.24]; P = 0.001) and composite clinical outcomes (33.0% vs 39.6%; HR 0.76 [0.59-0.97]; P = 0.027). CONCLUSIONS: Among participants in the CONNECT-HF trial, use of digital applications was modest but was associated with higher HF quality-of-care scores, including use of GDMT and better clinical outcomes. Although cause and effect cannot be determined from this study, the application of technology to guide GDMT use and dosing among patients with HFrEF warrants further investigation.

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Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

October 2022

Volume

28

Issue

10

Start / End Page

1487 / 1496

Location

United States

Related Subject Headings

  • United States
  • Stroke Volume
  • Prospective Studies
  • Humans
  • Hospitalization
  • Heart Failure
  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1110 Nursing
 

Citation

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Rao, V. N., Kaltenbach, L. A., Granger, B. B., Fonarow, G. C., Al-Khalidi, H. R., Albert, N. M., … Durham, North Carolina; Los Angeles, California; Cleveland, Ohio; Jackson, Misssissippi, Aurora, Colorado; Detroit, Michigan; Ewa Beach, Hawaii; Staten Island, New York, . (2022). The Association of Digital Health Application Use With Heart Failure Care and Outcomes: Insights From CONNECT-HF. J Card Fail, 28(10), 1487–1496. https://doi.org/10.1016/j.cardfail.2022.07.050
Rao, Vishal N., Lisa A. Kaltenbach, Bradi B. Granger, Gregg C. Fonarow, Hussein R. Al-Khalidi, Nancy M. Albert, Javed Butler, et al. “The Association of Digital Health Application Use With Heart Failure Care and Outcomes: Insights From CONNECT-HF.J Card Fail 28, no. 10 (October 2022): 1487–96. https://doi.org/10.1016/j.cardfail.2022.07.050.
Rao VN, Kaltenbach LA, Granger BB, Fonarow GC, Al-Khalidi HR, Albert NM, et al. The Association of Digital Health Application Use With Heart Failure Care and Outcomes: Insights From CONNECT-HF. J Card Fail. 2022 Oct;28(10):1487–96.
Rao, Vishal N., et al. “The Association of Digital Health Application Use With Heart Failure Care and Outcomes: Insights From CONNECT-HF.J Card Fail, vol. 28, no. 10, Oct. 2022, pp. 1487–96. Pubmed, doi:10.1016/j.cardfail.2022.07.050.
Rao VN, Kaltenbach LA, Granger BB, Fonarow GC, Al-Khalidi HR, Albert NM, Butler J, Allen LA, Lanfear DE, Ariely D, Miller JM, Brodsky MA, Lalonde TA, Lafferty JC, Granger CB, Hernandez AF, Devore AD, Durham, North Carolina; Los Angeles, California; Cleveland, Ohio; Jackson, Misssissippi, Aurora, Colorado; Detroit, Michigan; Ewa Beach, Hawaii; Staten Island, New York. The Association of Digital Health Application Use With Heart Failure Care and Outcomes: Insights From CONNECT-HF. J Card Fail. 2022 Oct;28(10):1487–1496.
Journal cover image

Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

October 2022

Volume

28

Issue

10

Start / End Page

1487 / 1496

Location

United States

Related Subject Headings

  • United States
  • Stroke Volume
  • Prospective Studies
  • Humans
  • Hospitalization
  • Heart Failure
  • Cardiovascular System & Hematology
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1110 Nursing