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Short-term cardiovascular events after bariatric surgery in patients with metabolic syndrome.

Publication ,  Journal Article
Chumakova-Orin, M; Ingram, JL; Que, LG; Pagidipati, N; Gordee, A; Kuchibhatla, M; Seymour, KA
Published in: Surg Obes Relat Dis
January 2024

BACKGROUND: Patients with metabolic syndrome (MetS) are at increased risk of developing cardiovascular disease along with other adverse events after bariatric surgery. OBJECTIVES: The incidence of short-term major adverse cardiovascular events (MACE) in patients with MetS undergoing bariatric surgery is not well characterized. SETTING: Accredited bariatric surgery centers in the United States and Canada. METHODS: A total of 760,076 patients aged ≥18 years with body mass index ≥35 kg/m2 who underwent primary bariatric surgery between 2015 and 2018 were included. Patients with both diabetes and hypertension were described as the MetS cohort. Patient characteristics, operative technique, and 30-day outcomes were compared. The primary outcome was incidence of MACE, a composite of myocardial infarction, stroke, and all-cause mortality. Unadjusted and multivariable logistic regression analyses were performed and included an interaction between MetS and hyperlipidemia (HLD). RESULTS: Of the 577,882 patients included, 111,128 (19.2%) exhibited MetS. Patients with MetS more frequently experienced MACE compared with patients without MetS (.3% versus .1%; P < .001). The odds of MACE were greater for patients with MetS versus Non-MetS (odds ratio [OR] 2.87; 95% CI, 2.49-3.32) in the unadjusted analysis. MetS without HLD, MetS with HLD, and Non-MetS with HLD are significantly associated with MACE when compared with those with non-MetS without HLD. CONCLUSIONS: Patients with MetS have an increased frequency of cardiac events following bariatric surgery. Future studies should determine if optimization of 1 or more components of MetS or other related co-morbidities reduces the cardiovascular risk for patients.

Duke Scholars

Published In

Surg Obes Relat Dis

DOI

EISSN

1878-7533

Publication Date

January 2024

Volume

20

Issue

1

Start / End Page

18 / 28

Location

United States

Related Subject Headings

  • United States
  • Surgery
  • Risk Factors
  • Retrospective Studies
  • Myocardial Infarction
  • Metabolic Syndrome
  • Hyperlipidemias
  • Humans
  • Comorbidity
  • Cardiovascular Diseases
 

Citation

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Chumakova-Orin, M., Ingram, J. L., Que, L. G., Pagidipati, N., Gordee, A., Kuchibhatla, M., & Seymour, K. A. (2024). Short-term cardiovascular events after bariatric surgery in patients with metabolic syndrome. Surg Obes Relat Dis, 20(1), 18–28. https://doi.org/10.1016/j.soard.2023.07.009
Chumakova-Orin, Maryna, Jennifer L. Ingram, Loretta G. Que, Neha Pagidipati, Alexander Gordee, Maragatha Kuchibhatla, and Keri A. Seymour. “Short-term cardiovascular events after bariatric surgery in patients with metabolic syndrome.Surg Obes Relat Dis 20, no. 1 (January 2024): 18–28. https://doi.org/10.1016/j.soard.2023.07.009.
Chumakova-Orin M, Ingram JL, Que LG, Pagidipati N, Gordee A, Kuchibhatla M, et al. Short-term cardiovascular events after bariatric surgery in patients with metabolic syndrome. Surg Obes Relat Dis. 2024 Jan;20(1):18–28.
Chumakova-Orin, Maryna, et al. “Short-term cardiovascular events after bariatric surgery in patients with metabolic syndrome.Surg Obes Relat Dis, vol. 20, no. 1, Jan. 2024, pp. 18–28. Pubmed, doi:10.1016/j.soard.2023.07.009.
Chumakova-Orin M, Ingram JL, Que LG, Pagidipati N, Gordee A, Kuchibhatla M, Seymour KA. Short-term cardiovascular events after bariatric surgery in patients with metabolic syndrome. Surg Obes Relat Dis. 2024 Jan;20(1):18–28.
Journal cover image

Published In

Surg Obes Relat Dis

DOI

EISSN

1878-7533

Publication Date

January 2024

Volume

20

Issue

1

Start / End Page

18 / 28

Location

United States

Related Subject Headings

  • United States
  • Surgery
  • Risk Factors
  • Retrospective Studies
  • Myocardial Infarction
  • Metabolic Syndrome
  • Hyperlipidemias
  • Humans
  • Comorbidity
  • Cardiovascular Diseases