Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy.
Publication
, Journal Article
Epplein, M; McCall, SJ; Wang, F; Alagesan, P; Brown, H; Wawrzynski, J; Labriola, C; Zuzul, R; Cook, C; Dillon, M; Hyslop, T; Patierno, SR ...
Published in: Clin Transl Gastroenterol
June 1, 2024
INTRODUCTION: We designed a race-conscious study to assess the presence of Helicobacter pylori v irulence factor cagA in a retrospective cohort of patients with active H. pylori infection. METHODS: We compared cagA status by race in gastric tissue samples from 473 patients diagnosed with active H. pylori infection from 2015 to 2019. RESULTS: H. pylori + Black patients were 2 times more likely to be cagA + than H. pylori + White patients (82% vs 36%, P < .0001). DISCUSSION: Presence of cagA is common among endoscopy patients with active H. pylori infection; appropriate testing and treatment of H. pylori can both reduce gastric cancer risk and address health disparities.
Duke Scholars
Published In
Clin Transl Gastroenterol
DOI
EISSN
2155-384X
Publication Date
June 1, 2024
Volume
15
Issue
6
Start / End Page
e1
Location
United States
Related Subject Headings
- White People
- Virulence Factors
- Stomach Neoplasms
- Retrospective Studies
- Prevalence
- Middle Aged
- Male
- Humans
- Helicobacter pylori
- Helicobacter Infections
Citation
APA
Chicago
ICMJE
MLA
NLM
Epplein, M., McCall, S. J., Wang, F., Alagesan, P., Brown, H., Wawrzynski, J., … Garman, K. S. (2024). Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy. Clin Transl Gastroenterol, 15(6), e1. https://doi.org/10.14309/ctg.0000000000000713
Epplein, Meira, Shannon J. McCall, Frances Wang, Priya Alagesan, HannahSofia Brown, Joseph Wawrzynski, Caroline Labriola, et al. “Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy.” Clin Transl Gastroenterol 15, no. 6 (June 1, 2024): e1. https://doi.org/10.14309/ctg.0000000000000713.
Epplein M, McCall SJ, Wang F, Alagesan P, Brown H, Wawrzynski J, et al. Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy. Clin Transl Gastroenterol. 2024 Jun 1;15(6):e1.
Epplein, Meira, et al. “Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy.” Clin Transl Gastroenterol, vol. 15, no. 6, June 2024, p. e1. Pubmed, doi:10.14309/ctg.0000000000000713.
Epplein M, McCall SJ, Wang F, Alagesan P, Brown H, Wawrzynski J, Labriola C, Zuzul R, Cook C, Dillon M, Hyslop T, Patierno SR, Salama NR, Garman KS. Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy. Clin Transl Gastroenterol. 2024 Jun 1;15(6):e1.
Published In
Clin Transl Gastroenterol
DOI
EISSN
2155-384X
Publication Date
June 1, 2024
Volume
15
Issue
6
Start / End Page
e1
Location
United States
Related Subject Headings
- White People
- Virulence Factors
- Stomach Neoplasms
- Retrospective Studies
- Prevalence
- Middle Aged
- Male
- Humans
- Helicobacter pylori
- Helicobacter Infections