Scholars@Duke publication: A framework for integrating the songbird brain.

A framework for integrating the songbird brain.

Publication , Journal Article

Jarvis, ED; Smith, VA; Wada, K; Rivas, MV; McElroy, M; Smulders, TV; Carninci, P; Hayashizaki, Y; Dietrich, F; Wu, X; McConnell, P; Yu, J ...

Published in: J Comp Physiol A Neuroethol Sens Neural Behav Physiol

December 2002

Published version (DOI) Open Access Copy (Duke) Link to item

Biological systems by default involve complex components with complex relationships. To decipher how biological systems work, we assume that one needs to integrate information over multiple levels of complexity. The songbird vocal communication system is ideal for such integration due to many years of ethological investigation and a discreet dedicated brain network. Here we announce the beginnings of a songbird brain integrative project that involves high-throughput, molecular, anatomical, electrophysiological and behavioral levels of analysis. We first formed a rationale for inclusion of specific biological levels of analysis, then developed high-throughput molecular technologies on songbird brains, developed technologies for combined analysis of electrophysiological activity and gene regulation in awake behaving animals, and developed bioinformatic tools that predict causal interactions within and between biological levels of organization. This integrative brain project is fitting for the interdisciplinary approaches taken in the current songbird issue of the Journal of Comparative Physiology A and is expected to be conducive to deciphering how brains generate and perceive complex behaviors.

Duke Scholars

Author Erich David Jarvis Neurobiology

Author Fred Samuel Dietrich Molecular Genetics and Microbiology

Author Alexander J. Hartemink Computer Science

Published In

J Comp Physiol A Neuroethol Sens Neural Behav Physiol

DOI

10.1007/s00359-002-0358-y

ISSN

0340-7594

Publication Date

December 2002

Volume

188

Issue

11-12

Start / End Page

961 / 980

Location

Germany

Related Subject Headings

Vocalization, Animal
Transcription Factors
Songbirds
Neurology & Neurosurgery
Neural Networks, Computer
Nerve Net
Motor Activity
Models, Neurological
Learning
Gene Library

Citation

APA

Chicago

ICMJE

MLA

NLM

Jarvis, E. D., Smith, V. A., Wada, K., Rivas, M. V., McElroy, M., Smulders, T. V., … Lin, S. (2002). A framework for integrating the songbird brain. J Comp Physiol A Neuroethol Sens Neural Behav Physiol, 188(11–12), 961–980. https://doi.org/10.1007/s00359-002-0358-y

Jarvis, E. D., V. A. Smith, K. Wada, M. V. Rivas, M. McElroy, T. V. Smulders, P. Carninci, et al. “A framework for integrating the songbird brain.” J Comp Physiol A Neuroethol Sens Neural Behav Physiol 188, no. 11–12 (December 2002): 961–80. https://doi.org/10.1007/s00359-002-0358-y.

Jarvis ED, Smith VA, Wada K, Rivas MV, McElroy M, Smulders TV, et al. A framework for integrating the songbird brain. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2002 Dec;188(11–12):961–80.

Jarvis, E. D., et al. “A framework for integrating the songbird brain.” J Comp Physiol A Neuroethol Sens Neural Behav Physiol, vol. 188, no. 11–12, Dec. 2002, pp. 961–80. Pubmed, doi:10.1007/s00359-002-0358-y.

Jarvis ED, Smith VA, Wada K, Rivas MV, McElroy M, Smulders TV, Carninci P, Hayashizaki Y, Dietrich F, Wu X, McConnell P, Yu J, Wang PP, Hartemink AJ, Lin S. A framework for integrating the songbird brain. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2002 Dec;188(11–12):961–980.

Published In

J Comp Physiol A Neuroethol Sens Neural Behav Physiol

DOI

10.1007/s00359-002-0358-y

ISSN

0340-7594

Publication Date

December 2002

Volume

188

Issue

11-12

Start / End Page

961 / 980

Location

Germany

Related Subject Headings

Vocalization, Animal
Transcription Factors
Songbirds
Neurology & Neurosurgery
Neural Networks, Computer
Nerve Net
Motor Activity
Models, Neurological
Learning
Gene Library