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Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task.

Publication ,  Journal Article
Browndyke, JN; Paskavitz, J; Sweet, LH; Cohen, RA; Tucker, KA; Welsh-Bohmer, KA; Burke, JR; Schmechel, DE
Published in: Brain Inj
June 2008

PRIMARY OBJECTIVE: Event-related, functional magnetic resonance imaging (fMRI) data were acquired in healthy participants during purposefully malingered and normal recognition memory performances to evaluate the neural substrates of feigned memory impairment. METHODS AND PROCEDURES: Pairwise, between-condition contrasts of neural activity associated with discrete recognition memory responses were conducted to isolate dissociable neural activity between normal and malingered responding while simultaneously controlling for shared stimulus familiarity and novelty effects. Response timing characteristics were also examined for any association with observed between-condition activity differences. OUTCOMES AND RESULTS: Malingered recognition memory errors, regardless of type, were associated with inferior parietal and superior temporal activity relative to normal performance, while feigned recognition target misses produced additional dorsomedial frontal activation and feigned foil false alarms activated bilateral ventrolateral frontal regions. Malingered response times were associated with activity in the dorsomedial frontal, temporal and inferior parietal regions. Normal memory responses were associated with greater inferior occipitotemporal and dorsomedial parietal activity, suggesting greater reliance upon visual/attentional networks for proper task performance. CONCLUSIONS: The neural substrates subserving feigned recognition memory deficits are influenced by response demand and error type, producing differential activation of cortical regions important to complex visual processing, executive control, response planning and working memory processes.

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Published In

Brain Inj

DOI

EISSN

1362-301X

Publication Date

June 2008

Volume

22

Issue

6

Start / End Page

481 / 489

Location

England

Related Subject Headings

  • Rehabilitation
  • Regression Analysis
  • Reaction Time
  • Neuropsychological Tests
  • Memory Disorders
  • Malingering
  • Male
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Browndyke, J. N., Paskavitz, J., Sweet, L. H., Cohen, R. A., Tucker, K. A., Welsh-Bohmer, K. A., … Schmechel, D. E. (2008). Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task. Brain Inj, 22(6), 481–489. https://doi.org/10.1080/02699050802084894
Browndyke, Jeffrey N., James Paskavitz, Lawrence H. Sweet, Ronald A. Cohen, Karen A. Tucker, Kathleen A. Welsh-Bohmer, James R. Burke, and Donald E. Schmechel. “Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task.Brain Inj 22, no. 6 (June 2008): 481–89. https://doi.org/10.1080/02699050802084894.
Browndyke JN, Paskavitz J, Sweet LH, Cohen RA, Tucker KA, Welsh-Bohmer KA, et al. Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task. Brain Inj. 2008 Jun;22(6):481–9.
Browndyke, Jeffrey N., et al. “Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task.Brain Inj, vol. 22, no. 6, June 2008, pp. 481–89. Pubmed, doi:10.1080/02699050802084894.
Browndyke JN, Paskavitz J, Sweet LH, Cohen RA, Tucker KA, Welsh-Bohmer KA, Burke JR, Schmechel DE. Neuroanatomical correlates of malingered memory impairment: event-related fMRI of deception on a recognition memory task. Brain Inj. 2008 Jun;22(6):481–489.

Published In

Brain Inj

DOI

EISSN

1362-301X

Publication Date

June 2008

Volume

22

Issue

6

Start / End Page

481 / 489

Location

England

Related Subject Headings

  • Rehabilitation
  • Regression Analysis
  • Reaction Time
  • Neuropsychological Tests
  • Memory Disorders
  • Malingering
  • Male
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Humans