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Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies.

Publication ,  Journal Article
Vu, HM; Myers, D; de Lorimier, R; Matthews, TJ; Moody, MA; Heinly, C; Torres, JV; Haynes, BF; Spicer, L
Published in: J Virol
January 1999

Immunogenic peptides containing epitopes of the gp120 C4 and V3 regions from human immunodeficiency virus strains MN and EV91 have been studied by nuclear magnetic resonance and molecular modeling and used as immunogens in rhesus monkeys. The results, combined with those for other peptides, suggest a correlation between solution conformation and immunologic cross-reactivity.

Duke Scholars

Published In

J Virol

DOI

ISSN

0022-538X

Publication Date

January 1999

Volume

73

Issue

1

Start / End Page

746 / 750

Location

United States

Related Subject Headings

  • Virology
  • Structure-Activity Relationship
  • Protein Conformation
  • Molecular Sequence Data
  • Models, Biological
  • Magnetic Resonance Spectroscopy
  • Macaca mulatta
  • HIV Envelope Protein gp120
  • HIV Antibodies
  • Cross Reactions
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Vu, H. M., Myers, D., de Lorimier, R., Matthews, T. J., Moody, M. A., Heinly, C., … Spicer, L. (1999). Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies. J Virol, 73(1), 746–750. https://doi.org/10.1128/JVI.73.1.746-750.1999
Vu, H. M., D. Myers, R. de Lorimier, T. J. Matthews, M. A. Moody, C. Heinly, J. V. Torres, B. F. Haynes, and L. Spicer. “Nuclear magnetic resonance analysis of solution conformations in C4-V3 hybrid peptides derived from human immunodeficiency virus (HIV) type 1 gp120: relation to specificity of peptide-induced anti-HIV neutralizing antibodies.J Virol 73, no. 1 (January 1999): 746–50. https://doi.org/10.1128/JVI.73.1.746-750.1999.

Published In

J Virol

DOI

ISSN

0022-538X

Publication Date

January 1999

Volume

73

Issue

1

Start / End Page

746 / 750

Location

United States

Related Subject Headings

  • Virology
  • Structure-Activity Relationship
  • Protein Conformation
  • Molecular Sequence Data
  • Models, Biological
  • Magnetic Resonance Spectroscopy
  • Macaca mulatta
  • HIV Envelope Protein gp120
  • HIV Antibodies
  • Cross Reactions