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Primary meningeal rhabdomyosarcoma.

Publication ,  Journal Article
Palta, M; Riedel, RF; Vredenburgh, JJ; Cummings, TJ; Green, S; Chang, Z; Kirkpatrick, JP
Published in: Sarcoma
January 2011

Primary meningeal rhabdomyosarcoma is a rare primary brain malignancy, with scant case reports. While most reports of primary intracranial rhabdomyosarcoma occur in pediatric patients, a handful of cases in adult patients have been reported in the medical literature. We report the case of a 44-year-old male who developed primary meningeal rhabdomyosarcoma. After developing episodes of right lower extremity weakness, word finding difficulty, and headaches, a brain magnetic resonance imaging (MRI) demonstrated a vertex lesion with radiographic appearance of a meningeal-derived tumor. Subtotal surgical resection was performed due to sagittal sinus invasion and initial pathology was interpreted as an anaplastic meningioma. Re-review of pathology demonstrated rhabdomyosarcoma negative for alveolar translocation t(2;13). Staging studies revealed no evidence of disseminated disease. He was treated with stereotactic radiotherapy with concurrent temozolamide to be followed by vincristine, actinomycin-D, and cyclophosphamide (VAC) systemic therapy.

Duke Scholars

Published In

Sarcoma

DOI

EISSN

1369-1643

ISSN

1357-714X

Publication Date

January 2011

Volume

2011

Start / End Page

312802

Related Subject Headings

  • Oncology & Carcinogenesis
  • 3211 Oncology and carcinogenesis
  • 3203 Dentistry
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Palta, M., Riedel, R. F., Vredenburgh, J. J., Cummings, T. J., Green, S., Chang, Z., & Kirkpatrick, J. P. (2011). Primary meningeal rhabdomyosarcoma. Sarcoma, 2011, 312802. https://doi.org/10.1155/2011/312802
Palta, Manisha, Richard F. Riedel, James J. Vredenburgh, Thomas J. Cummings, Scott Green, Zheng Chang, and John P. Kirkpatrick. “Primary meningeal rhabdomyosarcoma.Sarcoma 2011 (January 2011): 312802. https://doi.org/10.1155/2011/312802.
Palta M, Riedel RF, Vredenburgh JJ, Cummings TJ, Green S, Chang Z, et al. Primary meningeal rhabdomyosarcoma. Sarcoma. 2011 Jan;2011:312802.
Palta, Manisha, et al. “Primary meningeal rhabdomyosarcoma.Sarcoma, vol. 2011, Jan. 2011, p. 312802. Epmc, doi:10.1155/2011/312802.
Palta M, Riedel RF, Vredenburgh JJ, Cummings TJ, Green S, Chang Z, Kirkpatrick JP. Primary meningeal rhabdomyosarcoma. Sarcoma. 2011 Jan;2011:312802.

Published In

Sarcoma

DOI

EISSN

1369-1643

ISSN

1357-714X

Publication Date

January 2011

Volume

2011

Start / End Page

312802

Related Subject Headings

  • Oncology & Carcinogenesis
  • 3211 Oncology and carcinogenesis
  • 3203 Dentistry
  • 3202 Clinical sciences
  • 1112 Oncology and Carcinogenesis
  • 1103 Clinical Sciences