Journal ArticleNorth American Spine Society Journal · December 1, 2024
Background: Traumatic thoracolumbar fracture fixation without neurological injury can be performed using the traditional open, mini-open Wiltse, and percutaneous approaches. This systematic review and meta-analysis aims to compare perioperative outcomes be ...
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Journal ArticleGlobal Spine J · September 2024
STUDY DESIGN: Systematic literature review and meta-analysis. OBJECTIVES: Predicting patient risk of intraoperative neuromonitoring (IONM) alerts preoperatively can aid patient counselling and surgical planning. Sielatycki et al established an axial-MRI-ba ...
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Journal ArticleSpine Deform · September 2024
PURPOSE: The role of robotics in spine surgery remains controversial, especially for scoliosis correction surgery. This study aims to assess the safety and efficacy of robotic-assisted (RA) surgery specifically for scoliosis surgery by comparing RA to both ...
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Journal ArticleJ Neurotrauma · September 2024
Cervical spine injuries (CSIs) are heterogeneous in nature and often lead to long-term disability and morbidity. However, there are few recent and comprehensive epidemiological studies on CSI. The objective of this study was to characterize recent trends i ...
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Journal ArticleWorld Neurosurg · August 2024
BACKGROUND: The rise of minimally invasive lumbar fusions and advanced imaging technologies has facilitated the introduction of novel surgical techniques with the trans-facet approach being one of the newest additions. We aimed to quantify any pathology-dr ...
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Journal ArticleJ Spine Surg · June 21, 2024
BACKGROUND: Ultra-minimally invasive percutaneous lumbar interbody fusion (percLIF) has been demonstrated to further minimize tissue trauma and has been associated with improved clinical outcomes including decreased blood loss, post-operative pain and leng ...
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Journal ArticleWorld Neurosurg · June 2024
BACKGROUND: Opioids are often prescribed for patients who eventually undergo lumbar decompression. Given the potential for opioid-related morbidity and mortality, postoperative weaning is often a goal of surgery. The purpose of this study was to examine th ...
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Journal ArticleJ Clin Med · April 20, 2024
The introduction of minimally invasive surgery ushered in a new era of spine surgery by minimizing the undue iatrogenic injury, recovery time, and blood loss, among other complications, of traditional open procedures. Over time, technological advancements ...
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Journal ArticleJ Clin Med · April 15, 2024
Background/Objectives: Lateral spine surgery offers effective minimally invasive deformity correction, but traditional approaches often involve separate anterior, lateral, and posterior procedures. The prone lateral technique streamlines this process by al ...
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Journal ArticleJ Clin Med · April 14, 2024
The transforaminal lumbar interbody fusion (TLIF) has seen significant evolution since its early inception, reflecting advancements in surgical techniques, patient safety, and outcomes. Originally described as an improvement over the posterior lumbar inter ...
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Journal ArticleJ Neurosurg Case Lessons · April 8, 2024
BACKGROUND: Robot-assisted sacroiliac joint (SIJ) fusion has gained popularity, but it carries the risk of complications such as injury to the superior gluteal artery (SGA). The authors present the case of an awake percutaneous robot-assisted SIJ fusion le ...
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Journal ArticleJ Clin Med · April 6, 2024
Cervical endoscopic spine surgery is rapidly evolving and gaining popularity for the treatment of cervical radiculopathy and myelopathy. This approach significantly reduces muscular damage and blood loss by minimizing soft tissue stripping, leading to less ...
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Journal ArticleJ Clin Med · March 6, 2024
The transfacet minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is a novel approach available for the management of lumbar spondylolisthesis. It avoids the need to manipulate either of the exiting or traversing nerve roots, both protect ...
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Journal ArticleInt J Spine Surg · March 4, 2024
BACKGROUND: Postoperative spinal epidural hematomas (pSEHs) are a rare complication of microdiscectomy surgery. The hematoma may be unnoticed intraoperatively, but timely treatment may prevent permanent neurologic impairment. Airway management in patients ...
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Journal ArticleJ Clin Med · February 16, 2024
The Prone Transpsoas (PTP) approach to lumbar spine surgery, emerging as an evolution of lateral lumbar interbody fusion (LLIF), offers significant advantages over traditional methods. PTP has demonstrated increased lumbar lordosis gains compared to LLIF, ...
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Journal ArticlePlast Reconstr Surg · January 1, 2024
BACKGROUND: Patients with oncologic spine disease face a high systemic illness burden and often require surgical intervention to alleviate pain and maintain spine stability. Wound healing complications are the most common reason for reoperation in this pop ...
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Journal ArticleOper Neurosurg (Hagerstown) · December 27, 2023
BACKGROUND AND OBJECTIVES: There has been a rise in minimally invasive methods to access the intervertebral disk space posteriorly given their decreased tissue destruction, lower blood loss, and earlier return to work. Two such options include the percutan ...
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Journal ArticleInt J Spine Surg · December 26, 2023
BACKGROUND: There has been heightened interest in performing percutaneous lumbar interbody fusions (percLIFs) through Kambin's triangle, an anatomic corridor allowing entrance into the disc space. However, due to its novelty, there are limited data regardi ...
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Journal ArticleWorld Neurosurg · December 2023
INTRODUCTION: Anterior cervical discectomy and fusion (ACDF) is among the most common spine procedures. Adjacent segment disease (ASD), characterized by degenerative disease at an adjacent spinal level to a prior fusion, is a well-recognized and significan ...
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Journal ArticleNorth American Spine Society Journal · December 1, 2024
Background: Traumatic thoracolumbar fracture fixation without neurological injury can be performed using the traditional open, mini-open Wiltse, and percutaneous approaches. This systematic review and meta-analysis aims to compare perioperative outcomes be ...
Full textCite
Journal ArticleGlobal Spine J · September 2024
STUDY DESIGN: Systematic literature review and meta-analysis. OBJECTIVES: Predicting patient risk of intraoperative neuromonitoring (IONM) alerts preoperatively can aid patient counselling and surgical planning. Sielatycki et al established an axial-MRI-ba ...
Full textLink to itemCite
Journal ArticleSpine Deform · September 2024
PURPOSE: The role of robotics in spine surgery remains controversial, especially for scoliosis correction surgery. This study aims to assess the safety and efficacy of robotic-assisted (RA) surgery specifically for scoliosis surgery by comparing RA to both ...
Full textLink to itemCite
Journal ArticleJ Neurotrauma · September 2024
Cervical spine injuries (CSIs) are heterogeneous in nature and often lead to long-term disability and morbidity. However, there are few recent and comprehensive epidemiological studies on CSI. The objective of this study was to characterize recent trends i ...
Full textOpen AccessLink to itemCite
Journal ArticleWorld Neurosurg · August 2024
BACKGROUND: The rise of minimally invasive lumbar fusions and advanced imaging technologies has facilitated the introduction of novel surgical techniques with the trans-facet approach being one of the newest additions. We aimed to quantify any pathology-dr ...
Full textOpen AccessLink to itemCite
Journal ArticleJ Spine Surg · June 21, 2024
BACKGROUND: Ultra-minimally invasive percutaneous lumbar interbody fusion (percLIF) has been demonstrated to further minimize tissue trauma and has been associated with improved clinical outcomes including decreased blood loss, post-operative pain and leng ...
Full textLink to itemCite
Journal ArticleWorld Neurosurg · June 2024
BACKGROUND: Opioids are often prescribed for patients who eventually undergo lumbar decompression. Given the potential for opioid-related morbidity and mortality, postoperative weaning is often a goal of surgery. The purpose of this study was to examine th ...
Full textLink to itemCite
Journal ArticleJ Clin Med · April 20, 2024
The introduction of minimally invasive surgery ushered in a new era of spine surgery by minimizing the undue iatrogenic injury, recovery time, and blood loss, among other complications, of traditional open procedures. Over time, technological advancements ...
Full textOpen AccessLink to itemCite
Journal ArticleJ Clin Med · April 15, 2024
Background/Objectives: Lateral spine surgery offers effective minimally invasive deformity correction, but traditional approaches often involve separate anterior, lateral, and posterior procedures. The prone lateral technique streamlines this process by al ...
Full textOpen AccessLink to itemCite
Journal ArticleJ Clin Med · April 14, 2024
The transforaminal lumbar interbody fusion (TLIF) has seen significant evolution since its early inception, reflecting advancements in surgical techniques, patient safety, and outcomes. Originally described as an improvement over the posterior lumbar inter ...
Full textOpen AccessLink to itemCite
Journal ArticleJ Neurosurg Case Lessons · April 8, 2024
BACKGROUND: Robot-assisted sacroiliac joint (SIJ) fusion has gained popularity, but it carries the risk of complications such as injury to the superior gluteal artery (SGA). The authors present the case of an awake percutaneous robot-assisted SIJ fusion le ...
Full textLink to itemCite
Journal ArticleJ Clin Med · April 6, 2024
Cervical endoscopic spine surgery is rapidly evolving and gaining popularity for the treatment of cervical radiculopathy and myelopathy. This approach significantly reduces muscular damage and blood loss by minimizing soft tissue stripping, leading to less ...
Full textLink to itemCite
Journal ArticleJ Clin Med · March 6, 2024
The transfacet minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is a novel approach available for the management of lumbar spondylolisthesis. It avoids the need to manipulate either of the exiting or traversing nerve roots, both protect ...
Full textOpen AccessLink to itemCite
Journal ArticleInt J Spine Surg · March 4, 2024
BACKGROUND: Postoperative spinal epidural hematomas (pSEHs) are a rare complication of microdiscectomy surgery. The hematoma may be unnoticed intraoperatively, but timely treatment may prevent permanent neurologic impairment. Airway management in patients ...
Full textLink to itemCite
Journal ArticleJ Clin Med · February 16, 2024
The Prone Transpsoas (PTP) approach to lumbar spine surgery, emerging as an evolution of lateral lumbar interbody fusion (LLIF), offers significant advantages over traditional methods. PTP has demonstrated increased lumbar lordosis gains compared to LLIF, ...
Full textOpen AccessLink to itemCite
Journal ArticlePlast Reconstr Surg · January 1, 2024
BACKGROUND: Patients with oncologic spine disease face a high systemic illness burden and often require surgical intervention to alleviate pain and maintain spine stability. Wound healing complications are the most common reason for reoperation in this pop ...
Full textOpen AccessLink to itemCite
Journal ArticleOper Neurosurg (Hagerstown) · December 27, 2023
BACKGROUND AND OBJECTIVES: There has been a rise in minimally invasive methods to access the intervertebral disk space posteriorly given their decreased tissue destruction, lower blood loss, and earlier return to work. Two such options include the percutan ...
Full textOpen AccessLink to itemCite
Journal ArticleInt J Spine Surg · December 26, 2023
BACKGROUND: There has been heightened interest in performing percutaneous lumbar interbody fusions (percLIFs) through Kambin's triangle, an anatomic corridor allowing entrance into the disc space. However, due to its novelty, there are limited data regardi ...
Full textOpen AccessLink to itemCite
Journal ArticleWorld Neurosurg · December 2023
INTRODUCTION: Anterior cervical discectomy and fusion (ACDF) is among the most common spine procedures. Adjacent segment disease (ASD), characterized by degenerative disease at an adjacent spinal level to a prior fusion, is a well-recognized and significan ...
Full textOpen AccessLink to itemCite
Journal ArticleOperative Techniques in Orthopaedics · December 1, 2023
Hip fractures are devastating injuries for the elderly and an increasing burden to the healthcare system. Cervical spondylotic myelopathy (CSM), as a common cause of disability, instability, and falls in the elderly population, places patients at risk for ...
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Journal ArticleNeurosurgery · November 1, 2023
BACKGROUND AND OBJECTIVES: The prone transpsoas (PTP) approach for lateral lumbar interbody fusion (LLIF) is a novel technique for degenerative lumbar spine disease. However, there is a paucity of information in the literature on the complications of this ...
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Journal ArticleEur Spine J · November 2023
PURPOSE: The number of articles retracted by peer-reviewed journals has increased in recent years. This study systematically reviews retracted publications in the spine surgery literature. METHODS: A search of PubMed MEDLINE, Ovid EMBASE, Retraction Watch, ...
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Journal ArticleNeurosurg Clin N Am · October 2023
Outcome assessment in adult spinal deformity has evolved from radiographic analysis of curve correction to patient-centered perception of health-related quality-of-life. Oswestry Disability Index and the Scoliosis Research Society-22 Patient Questionnaire ...
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Journal ArticleJ Spine Surg · September 22, 2023
Surgical correction of fixed kyphotic deformity or severe sagittal imbalance traditionally involves three column osteotomies, which are associated with high morbidity rates. Anterior column realignment (ACR) has emerged as a minimally invasive alternative ...
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Journal ArticleJ Neurotrauma · September 2023
Only 100 years ago, traumatic spinal cord injury (SCI) was commonly lethal. Today, most people who sustain SCI survive with continual efforts to improve their quality of life and neurological outcomes. SCI epidemiology is changing as preventative intervent ...
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Journal ArticleJ Neurotrauma · September 2023
There is a paucity of data comparing the demographics, mechanism of injury, and outcomes of upper versus lower cervical spinal cord injuries (cSCI). The study objective was to define different clinical manifestations of cSCI. Data were collected prospectiv ...
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Journal ArticleJ Neurotrauma · September 2023
The bulbocavernosus reflex (BCR) has been used during the initial evaluation of a spinal cord injury patient as a metric to determine prognosis and whether the patient is in "spinal shock." This reflex has been less utilized over the last decade, and there ...
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Journal ArticleJ Neurotrauma · September 2023
Abstract The North America Clinical Trials Network (NACTN) for Spinal Cord Injury (SCI) is a consortium of tertiary medical centers that has maintained a prospective SCI registry since 2004, and it has espoused that early surgical intervention is associate ...
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Journal ArticleJ Neurotrauma · September 2023
Data supporting the benefits of early surgical intervention in acute spinal cord injury (SCI) is growing. For early surgery to be accomplished, understanding the causes of variabilities that effect the timing of surgery is needed to achieve this goal. The ...
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Journal ArticleNat Commun · August 11, 2023
Unlike adult mammals, zebrafish regenerate spinal cord tissue and recover locomotor ability after a paralyzing injury. Here, we find that ependymal cells in zebrafish spinal cords produce the neurogenic factor Hb-egfa upon transection injury. Animals with ...
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Journal ArticleWorld Neurosurg · August 2023
OBJECTIVE: There is increasing interest in performing awake spinal fusion under spinal anesthesia (SA). Evidence supporting SA has been positive, albeit limited. The authors set out to investigate the effects of SA versus general anesthesia (GA) for spinal ...
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Journal ArticleWorld Neurosurg · June 22, 2023
OBJECTIVE: While Kambin's Triangle has become an ever more important anatomic window given its proximity to the exiting nerve root, there have been limited studies examining the effect of disease on the corridor. Our goal was to better understand how patho ...
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Journal ArticleWorld Neurosurg · June 12, 2023
BACKGROUND: High-energy traumatic sacral fractures, particularly U-type or AOSpine classification type C fractures, may lead to significant functional deficits. Traditionally, spinopelvic fixation for unstable sacral fractures was performed with open reduc ...
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Journal ArticleNeurochirurgie · May 2023
BACKGROUND: Annually, hundreds of thousands of patients undergo surgery for degenerative spine disease (DSD). This represents only a fraction of patients that present for surgical consideration. Procedures are often avoided due to comorbidities that make p ...
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Journal ArticleWorld Neurosurg · April 2023
BACKGROUND: The accuracy of pedicle screws placed with instrument tracking and robotic navigation are individually comparable or superior to placement using standard fluoroscopy, however head-to-head comparisons between these adjuncts in a similar surgical ...
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Journal ArticleOper Neurosurg (Hagerstown) · March 1, 2023
BACKGROUND: Minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) and MIS lumbar decompression have been successfully undertaken in the absence of general anesthesia in well-selected patients. By leveraging spinal anesthesia, surgeons may sa ...
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Journal ArticleOper Neurosurg (Hagerstown) · March 1, 2023
BACKGROUND: For percutaneous lumbar fusion (percLIF), magnetic resonance imaging and computed tomography are critical to defining surgical corridors. Currently, these scans are performed separately, and surgeons then use fluoroscopy or neuromonitoring to g ...
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Journal ArticleEur J Orthop Surg Traumatol · January 2023
PURPOSE: Robot-assisted pelvic screw fixation is a new technology with promising benefits on intraoperative outcomes for patients with posterior pelvic ring injuries. We aim to compare robot-assisted pelvic screw fixation to the traditional fluoroscopy-ass ...
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Journal ArticleWorld Neurosurg · January 2023
The prone lateral transpsoas approach for lumbar interbody fusion and posterior instrumentation enables a large surface area implant without disruption of the posterior spine musculature from a single position.1,2 The addition of virtual live fluoroscopy i ...
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Journal ArticleNeurosurg Focus · January 2023
OBJECTIVE: The authors sought to analyze the current literature to determine dimensional trends across the lumbar levels of Kambin's triangle, clarify the role of imaging techniques for preoperative planning, and understand the effect of inclusion of the s ...
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Journal ArticleNeurosurg Focus · January 2023
OBJECTIVE: The aim of this paper was to evaluate the changes in radiographic spinopelvic parameters in a large cohort of patients undergoing the prone transpsoas approach to the lumbar spine. METHODS: A multicenter retrospective observational cohort study ...
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Journal ArticleIBRO Neurosci Rep · December 2022
Surgical techniques and technology are steadily improving, thereby expanding the pool of patients amenable for spine surgery. The growing and aging population in the United States further contributes to the increase in spine surgery cases. Traditionally, s ...
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Journal ArticleJ Surg Case Rep · December 2022
Dermoid cysts rarely present in the retroperitoneal space or during adulthood. In this case report, we describe the clinical presentation, operative and post-operative course of a 31-year old with a retroperitoneal dermoid cyst. The patient presented with ...
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Journal ArticleJ Clin Neurophysiol · November 1, 2022
With the versatility of lumbar spine surgery continually expanding, intraoperative electromyography (EMG) has become a common adjunct used to reduce risk of nerve injury and postoperative neurologic deficit. EMG monitoring has been deemed particularly usef ...
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Journal ArticleEur Spine J · September 2022
PURPOSE: Prone transpsoas fusion (PTP) is a minimally invasive technique that maximizes the benefit of lateral access interbody surgery and the prone positioning for surgically significant adjacent segment disease. The authors describe the feasibility, rep ...
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Journal ArticleNeurospine · September 2022
Acute traumatic spinal cord injury (SCI) can be a devastating and costly event for individuals, their families, and the health system as a whole. Prognosis is heavily dependent on the physical extent of the injury and the severity of neurological dysfuncti ...
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Journal ArticleNeurospine · September 2022
Physical rehabilitation is essential for enhancing recovery in individuals with spinal cord injury (SCI); however, aside from early surgical intervention and hemodynamic management, there are no proven interventions for promoting recovery in the acute phas ...
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ConferenceOper Neurosurg (Hagerstown) · July 1, 2022
BACKGROUND: Patients undergoing sacroiliac (SI) fusion can oftentimes experience significant improvements in pain and quality of life. OBJECTIVE: To describe a novel application of robotic navigation to assist with minimally invasive SI joint fusion. METHO ...
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Journal ArticleJ Clin Orthop Trauma · July 2022
STUDY DESIGN: Meta-analysis. OBJECTIVES: Perform a systematic review and meta-analysis to determine the perioperative utility of general versus spinal anesthesia in the lumbar spine surgery population. METHODS: PubMed and Embase were queried for manuscript ...
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Journal ArticleNeurosurg Focus Video · July 2022
In this video, the authors highlight the operative treatment of a 55-year-old man with chronic osteomyelitis discitis. The operation entailed a minimally invasive lateral retroperitoneal transpsoas approach for L3 and L4 corpectomies, L2-5 interbody fusion ...
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Journal ArticleWorld Neurosurg · June 2022
In recent years, physicians and institutions have come to recognize the increasing opioid epidemic in the United States, thus prompting a dramatic shift in opioid prescribing patterns. The lack of well-studied alternative treatment regimens has led to a su ...
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Journal ArticleClin Spine Surg · February 1, 2022
STUDY DESIGN: Retrospective cohort study using the National Surgical Quality Improvement Program. OBJECTIVE: The objective of this study was to identify preoperative factors that impact the decision to perform prophylactic muscle flap closure and assess ri ...
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Journal ArticleFront Surg · 2022
Interest in robotic-assisted spine surgery has grown as surgeon comfort and technology has evolved to maximize benefits of time saving and precision. However, the Food and Drug Administration (FDA) has currently only approved robotics to assist in determin ...
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Journal ArticleJ Clin Neurosci · December 2021
Robotic navigation is a new and rapidly emerging niche within minimally invasive spine surgery. The robotic arms-race began in 2004 and has resulted in no less than four major robotic surgical adjuncts. Current Food and Drug Administration (FDA)-approved a ...
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Journal ArticleNeurosurg Focus · December 2021
OBJECTIVE: Despite tremendous advancements in biomedical science and surgical technique, spine surgeries are still associated with considerable rates of morbidity and mortality, particularly in the elderly. Multiple novel techniques have been employed in r ...
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Journal ArticleInt J Spine Surg · December 2021
BACKGROUND: There has been an increased interest in lumbar interbody fusions through Kambin's triangle. In this study, we describe percutaneous access to the lumbar disc and insertion of an expandable titanium cage through Kambin's triangle without facetec ...
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Journal ArticleInt J Spine Surg · December 2021
BACKGROUND: There has been an increased interest in lumbar interbody fusions through Kambin's triangle. In this study, we describe percutaneous access to the lumbar disc and insertion of an expandable titanium cage through Kambin's triangle without facetec ...
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Journal ArticleOper Neurosurg (Hagerstown) · November 15, 2021
BACKGROUND: Minimally invasive spine surgery (MISS) has the potential to further advance with the use of robot-assisted (RA) techniques. While RA pedicle screw placement has been extensively investigated, there is a lack of literature on the use of the rob ...
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Journal ArticleActa Neurochir (Wien) · November 2021
BACKGROUND: Robotic-assisted surgery is becoming more widely applied in surgical subspecialties due to its intraoperative and postoperative advantages such as minimally invasive approach, reduced blood loss, shorter hospital stay, and decreased incidence o ...
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Journal ArticleJ Clin Neurosci · September 2021
UNLABELLED: Primary spine tumors are rare neoplasms that affect about 0.62 per 100,000 individuals in the US. Intramedullary spinal cord tumors (IMSCTs) are the rarest of all primary tumors involving the spine and can cause pain, imbalance, urinary dysfunc ...
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Journal ArticleWorld Neurosurg · August 2021
BACKGROUND: Minimally invasive surgical techniques have resulted in improved patient outcomes. One drawback has been the increased reliance on fluoroscopy and subsequent exposure to ionizing radiation. We have previously shown the efficacy of a novel instr ...
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Journal ArticleJ Neurosurg Spine · August 1, 2021
OBJECTIVE: The rate of symptomatic adjacent-segment disease (ASD) after newer minimally invasive techniques, such as lateral lumbar interbody fusion (LLIF), is not known. This study aimed to assess the incidence of surgically significant ASD in adult patie ...
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Journal ArticleClin Neurol Neurosurg · July 2021
INTRODUCTION: Instrument-navigation modalities including CT-guided and robot-assisted methods claim both efficacy and accuracy when applied to spine surgery, yet often increase setup and operating times which can translate to increased costs. To see the im ...
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Journal ArticleOper Neurosurg (Hagerstown) · June 15, 2021
Spinal fusion has undergone significant evolution and improvement over the past 50 yr. Historically, spine fusion was noninstrumented and arthrodesis was based entirely on autograft. Improved understanding of spinal anatomy and materials science ushered in ...
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Journal ArticleJ Trauma Acute Care Surg · June 1, 2021
BACKGROUND: Traumatic spinal cord injury (SCI) is a serious public health problem. Outcomes are determined by severity of immediate injury, mitigation of secondary downstream effects, and rehabilitation. This study aimed to understand how the center type a ...
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Journal ArticleNeurosurg Focus · June 2021
OBJECTIVE: The use of osteobiologics, engineered materials designed to promote bone healing by enhancing bone growth, is becoming increasingly common for spinal fusion procedures, but the efficacy of some of these products is unclear. The authors performed ...
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Journal ArticleNeurosurg Focus · May 2021
OBJECTIVE: In patients with metastatic spinal disease (MSD), interhospital transfer can potentially impact clinical outcomes as the possible benefits of transferring a patient to a higher level of care must be weighed against the negative effects associate ...
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Journal ArticleClin Imaging · April 2021
BACKGROUND: Intraoperative computed tomography (CT) is becoming more widely utilized in spine fusion surgeries. The use of CT-based image guidance has been shown to increase the accuracy in instrumentation placement and to reduce the rate of reoperation. H ...
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ConferenceTechniques in Orthopaedics · March 1, 2021
As adult spinal deformity surgery becomes more prevalent, the rates of proximal junctional kyphosis (PJK) will rise proportionally. The exact mechanism of PJK is unknown. However, it is thought to be multifactorial and includes violation of the facets and ...
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Journal ArticleJ Neurosurg Spine · February 1, 2021
OBJECTIVE: Stereotactic body radiation therapy (SBRT) offers efficient, noninvasive treatment of spinal neoplasms. Single-fraction (SF) high-dose SBRT has a relatively narrow therapeutic window, while hypofractionated delivery of SBRT may have an improved ...
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Journal ArticleCancer Epidemiol · February 2021
BACKGROUND: The incidence of metastatic spine disease (MSD) is increasing among cancer patients. Given the poor outcomes and high rates of morbidity associated with MSD, it is important to determine demographic factors that could impact interventions and o ...
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Journal ArticleClin Neurol Neurosurg · January 2021
BACKGROUND CONTEXT: Preoperative optimization of medical comorbidities prior to spinal surgery is becoming an increasingly important intervention in decreasing postoperative complications and ensuring a satisfactory postoperative course. The treatment of p ...
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Journal ArticleJ Clin Neurosci · January 2021
STUDY DESIGN: Literature review. OBJECTIVES: It has been reported that 2.4-3.7% of all blunt trauma victims suffer some element of cervical spine fracture, with the majority of these patients suffering from C3-7 (subaxial) involvement. With the improvement ...
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Journal ArticleBrain Stimul · 2021
For patients who have lost sensory function due to a neurological injury such as spinal cord injury (SCI), stroke, or amputation, spinal cord stimulation (SCS) may provide a mechanism for restoring somatic sensations via an intuitive, non-visual pathway. I ...
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Journal ArticleFront Surg · 2021
Traumatic spinal cord injury (TSCI) is a debilitating disease that poses significant functional and economic burden on both the individual and societal levels. Prognosis is dependent on the extent of the spinal injury and the severity of neurological dysfu ...
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Journal ArticleGlobal Spine J · December 2020
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To perform a systematic review of clinical outcomes between stand-alone anchored spacers and traditional cages with plate fixation for dysphagia and pseudoarthrosis using data from clinical tria ...
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Journal ArticleNeurosurg Focus · November 2020
Spine surgery has been disproportionately impacted by medical liability and malpractice litigation, with the majority of claims and payouts related to procedural error. One common area for the potential avoidance of malpractice claims and subsequent payout ...
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Journal ArticleSpinal Cord Ser Cases · October 16, 2020
INTRODUCTION: Epidural electrical stimulation of the conus medullaris has helped facilitate native motor recovery in individuals with complete cervicothoracic spinal cord injuries (SCI). A theorized mechanism of clinical improvement includes supporting cen ...
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Journal ArticleJMIR Perioper Med · October 16, 2020
BACKGROUND: There is a great unmet clinical need to provide patients undergoing spinal surgery and their caregivers with ongoing, high-quality care before and after surgery in an efficiency-focused health care environment. OBJECTIVE: The objective of this ...
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Journal ArticleInterdisciplinary Neurosurgery: Advanced Techniques and Case Management · June 1, 2020
Awake surgeries are commonly performed in many specialties through the use of local or regional anesthesia. These methods avoid the risks associated with general endotracheal anesthesia and allow faster recovery times. In neurosurgery, awake surgeries are ...
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Journal ArticleInt J Spine Surg · June 2020
INTRODUCTION: As minimally invasive spine surgery gains popularity, a focused effort must be made to reduce intraoperative radiation exposure to levels as low as reasonably achievable. Here, we demonstrate the clinical efficacy of a novel technology to aid ...
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Journal ArticleWorld Neurosurg · December 2019
Spinal alignment, particularly with respect to spinopelvic parameters, is highly correlated with morbidity and health-related quality-of-life outcomes. Although the importance of spinal alignment has been emphasized in the deformity literature, spinopelvic ...
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Journal ArticleWorld Neurosurg · November 2019
BACKGROUND: The cervicothoracic junction (CTJ) has often been identified as an area of biomechanical vulnerability; however, few studies have examined the relative merits of extending fusions across this area. In this study, we sought to investigate the tr ...
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Journal ArticleAJR Am J Roentgenol · September 2019
OBJECTIVE. Compared with open procedures, minimally invasive surgical procedures are associated with increased radiation exposure and long-term health risks. Ultralow radiation imaging coupled with image enhancement and instrument tracking (ULRI-IE/IT) is ...
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Journal ArticleEmerg Radiol · June 2019
Visits to the emergency department by patients who have recently undergone neurosurgery are a common occurrence, and these patients frequently receive emergent cross-sectional head imaging in order to evaluate for complications. Different neurosurgical app ...
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Journal ArticleAnn Transl Med · May 2019
Primary and metastatic tumors of the spine represent a significant cause of patient morbidity, and present a management challenge to treating providers. From a neurosurgical standpoint, resection surgery may be warranted in cases of spinal instability, pro ...
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Journal ArticleNeurosurgery · March 1, 2019
BACKGROUND: Unplanned hospital readmissions contribute significantly to soaring national healthcare expenditures. To alleviate this burden, Centers for Medicare and Medicaid Services implemented initiatives to penalize hospitals for unplanned 30-d hospital ...
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Journal ArticleJ Neurosurg Spine · March 1, 2019
OBJECTIVEIn the United States, healthcare expenditures have been soaring at a concerning rate. There has been an excessive use of postoperative radiographs after spine surgery and this has been a target for hospitals to reduce unnecessary costs. However, t ...
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Journal ArticleJ Spine Surg · March 2019
BACKGROUND: For complex surgery, intraoperative ketamine administration is readily used to reduce post-operative pain. However, there have been a few studies suggesting that intraoperative ketamine may have deleterious effects and impact post-operative del ...
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Journal ArticleExp Neurol · January 2019
Spinal cord astrocytomas (SCAs) have discernibly unique signatures in regards to epidemiology, clinical oncological features, genetic markers, pathophysiology, and research and therapeutic challenges. Overall, there are presently very limited clinical mana ...
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Journal ArticleWorld Neurosurg · December 26, 2018
BACKGROUND: The use of postoperative cervical collars following cervical fusions is common practice. Its use has been purported to improve fusion rates and outcomes. There is a paucity in the strength of evidence to support its clinical benefit. Our object ...
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Journal ArticleJ Neurosurg Spine · December 1, 2018
OBJECTIVEPreemptive administration of analgesic medication is more effective than medication given after the onset of the painful stimulus. The efficacy of preoperative or preemptive pain relief after thoracolumbosacral spine surgery has not been well stud ...
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Journal ArticleClin Neurol Neurosurg · June 2018
OBJECTIVES: It is well-documented that geriatric patients are at risk for serious injuries after fracture due to pre-existing medical conditions, physical changes of aging, and medication effects. Frailty has been demonstrated to be a predictor of morbidit ...
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Journal ArticleNeuro Oncol · May 18, 2018
Intradural spinal tumors are rare tumors of the central nervous system. Due to the eloquence of the spinal cord and its tracts, the compact architecture of the cord and nerves, and the infiltrative nature of some of these tumors, surgical resection is diff ...
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Chapter · January 1, 2018
This chapter explores the vascular complications associated with cervical spine surgery for both anterior and posterior approaches. Recognizing that cervical decompression and instrumentation are common procedures, it is important to understand the complic ...
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Journal ArticleGlobal Spine J · October 2017
STUDY DESIGN: Review and technical report. OBJECTIVE: Intraoperative ultrasound has been used by spine surgeons since the early 1980s. Since that time, more advanced modes of intraoperative imaging and navigation have become widely available. Although the ...
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Journal ArticleJ Neurosurg · September 2017
OBJECTIVE Ventriculostomy entry sites are commonly selected by freehand estimation of Kocher's point or approximations from skull landmarks and a trajectory toward the ipsilateral frontal horn of the lateral ventricles. A recognized ventriculostomy complic ...
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Journal ArticleNeurology · January 10, 2017
OBJECTIVE: To use natural language processing (NLP) in conjunction with the electronic medical record (EMR) to accurately identify patients with cerebral aneurysms and their matched controls. METHODS: ICD-9 and Current Procedural Terminology codes were use ...
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Journal ArticleCell Transplant · December 13, 2016
The adult rodent spinal cord presents an inhibitory environment for donor cell survival, impeding efficiency for xenograft-based modeling of gliomas. We postulated that mild thermal preconditioning may influence the fate of the implanted tumor cells. To te ...
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Journal ArticleJ Neurosurg Pediatr · December 2016
The authors report a complex case of an 18-year-old male with a history of hydrocephalus secondary to intraventricular hemorrhage of prematurity, with more than 30 previous shunt revisions, who presented to the authors' institution with shunt malfunction. ...
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Journal ArticleJ Neurosurg Pediatr · December 2016
Severe os odontoideum causing ventral brainstem compression is a rare and difficult entity to treat. It is generally accepted that severe os odontoideum causing ventral brainstem compression and neurological deficits warrants surgical treatment. This often ...
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Journal ArticleNeurosurg Focus · December 2016
There is a wide group of lesions that may exist in the sellar and suprasellar regions. Embryologically, there is varying evidence that many of these entities may in fact represent a continuum of pathology deriving from a common ectodermal origin. The autho ...
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Journal ArticleNeurosurgery · September 2016
BACKGROUND: There are currently no satisfactory treatments or experimental models showing autonomic dysfunction for intramedullary spinal cord gliomas (ISCG). OBJECTIVE: To develop a rat model of ISCG and investigate whether genetically engineered human ne ...
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Journal ArticleBr J Neurosurg · August 2016
Background Intraoperative lumbar cerebrospinal fluid (CSF) drainage is a well-recognised technique in cranial and vascular surgery. The goal of the study was to assess the frequency and severity of intracranial hypotension post-intraoperative lumbar draina ...
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Journal ArticleJ Clin Neurosci · July 2016
Spinal cord gliomas, consisting mostly of ependymomas and astrocytomas, are rare entities. Of the gliomas, infiltrating astrocytomas are particularly challenging entities to treat due to their invasive nature. Surgical resection is oftentimes not possible ...
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Journal ArticleNeurocrit Care · April 2016
Subdural hematomas (SDHs), though frequently grouped together, can result from a variety of different etiologies, and therefore many different subtypes exist. Moreover, the high incidence of these lesions in the neurocritical care settings behooves practit ...
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Journal ArticleVision Res · February 2016
Rod pathways are a parallel set of synaptic connections which enable night vision by relaying and processing rod photoreceptor light responses. We use dim light stimuli to isolate rod pathway contributions to downstream light responses then characterize th ...
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Journal ArticleChilds Nerv Syst · January 2016
PURPOSE: In an era of residency duty-hour restrictions, there has been a recent effort to implement simulation-based training methods in neurosurgery teaching institutions. Several surgical simulators have been developed, ranging from physical models to so ...
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Journal ArticleWorld Neurosurg · November 2015
OBJECTIVE: Palliative tumor resection and subsequent stabilization are important for maximizing function and quality of life for patients suffering from spinal metastases. However, traditional operative techniques for spinal metastases with vertebral body ...
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Journal ArticleWorld Neurosurg · June 2015
BACKGROUND: There is accumulating evidence that extent of resection (EOR) in intrinsic brain tumor surgery prolongs overall survival (OS) and progression-free survival (PFS). One of the strategies to increase EOR is the use of intraoperative MRI (ioMRI); h ...
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Journal ArticleJ Neurosurg Spine · March 2015
Spinal epidural abscess (SEA) is a rare but often devastating infection of the epidural space around the spinal cord. When an SEA is widespread, extensive decompression with laminectomy is often impossible, as it may subject the patient to very long operat ...
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Journal ArticleJ Neurosurg Sci · December 2014
Chiari malformations refer to abnormalities of the hindbrain originally described by the Austrian pathologist Hans Chiari in the early 1890s. These malformations range from herniation of the cerebellar tonsils through the foramen magnum to complete agenesi ...
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Journal ArticleInt J Neurosci · June 2014
Surgical therapy for treatment-resistant obsessive compulsive disorder (OCD) remains an effective option for well-selected patients managed within a multidisciplinary setting. Historically, lesions within the limbic system have been used to control both ob ...
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Journal ArticleTremor Other Hyperkinet Mov (N Y) · 2014
BACKGROUND: Deep brain stimulation (DBS) has been utilized to treat various symptoms in patients suffering from movement disorders such as Parkinson's disease, dystonia, and essential tremor. Though ataxia syndromes have not been formally or frequently add ...
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Journal ArticleImaging Med · August 1, 2013
Patients with brain tumors provide a unique opportunity to understand functional brain plasticity. Using advanced imaging techniques, such as functional MRI and diffusion tensor imaging, we have gained tremendous knowledge of brain tumor behavior, transfor ...
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Journal ArticleChilds Nerv Syst · May 2013
INTRODUCTION: Neuroendoscopy has become an integral field within neurosurgery. It has allowed neurosurgeons unprecedented access to deep structures within both the cranial and spinal compartments, while allowing for minimal incisions, tissue retraction, an ...
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Journal ArticleEur Spine J · January 2012
OBJECTIVE: Vertebral body resection to treat spine tumors necessitates reconstruction to maintain spinal stability. The durability of reconstruction may be a challenge in cancer patients as treatment with chemotherapy and/or radiation coupled with poor nut ...
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Journal ArticleNeurosurgery · February 2011
Based on the clonal evolution model and the assumption that the vast majority of tumor cells are able to propagate and drive tumor growth, the goal of cancer treatment has traditionally been to kill all cancerous cells. This theory has been challenged rece ...
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Journal ArticleJ Clin Neurosci · February 2011
Rasmussen's encephalitis is characterized by seizures, progressive neurological deterioration and chronic inflammation of the brain. It typically presents in childhood and requires anatomic or functional hemispherectomy for seizure control. Here, we report ...
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Journal ArticlePediatr Neurosurg · 2011
BACKGROUND/AIMS: Recombinant human bone morphogenetic protein-2 (rhBMP-2) is responsible for multiple different signaling processes including positive effects on bone formation and fusion. In 2002, rhBMP-2 was approved for use in anterior lumbar spinal fus ...
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Journal ArticleAnat Rec (Hoboken) · January 2011
Cytokines are soluble mediators that are thought to act as communication signals between astroglia and neighboring neural cells. They are both released by, and act on, astroglia. It is hypothesized that it is this effect on astroglia that may be important ...
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Journal ArticleNeurosurg Clin N Am · January 2011
Contrary to the incidence of primary cancers, the incidence of brain metastasis has been increasing. This increase is likely because of the effects of an aging population, improved neuroimaging surveillance, and better control of systemic cancer, allowing ...
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Journal ArticleEpilepsy Behav · November 2010
A retrospective analysis of 43 patients with drop attack seizures who were treated with vagus nerve stimulation (VNS) was undertaken to determine the efficacy of VNS and to determine pre-implantation characteristics associated with VNS success. It was foun ...
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Journal ArticleNeurosurg Focus · August 2010
Given the tremendous success of deep brain stimulation (DBS) for the treatment of movement and neuropsychiatric disorders, clinicians have begun to open up to the possible use of electrical stimulation for the treatment of patients with uncontrolled seizur ...
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Journal ArticleJ Neurophysiol · September 2009
A monumental task of the mammalian retina is to encode an enormous range (>10(9)-fold) of light intensities experienced by the animal in natural environments. Retinal neurons carry out this task by dividing labor into many parallel rod and cone synaptic pa ...
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Journal ArticleJ Ocul Pharmacol Ther · April 2008
PURPOSE: The aim of this study was to evaluate whether intravitreal triamcinolone hexacetonide (TH) is a safe, longer lasting alternative to intravitreal triamcinolone acetonide (TA) in the rabbit eye. METHODS: Three groups, each comprising of 15 Dutch-bel ...
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Journal ArticleVision Res · December 2007
Bardet-Biedl syndrome (BBS) is an oligogenic syndrome whose manifestations include retinal degeneration, renal abnormalities, obesity and polydactylia. Evidence suggests that the main etiopathophysiology of this syndrome is impaired intraflagellar transpor ...
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Journal ArticleJ Physiol · April 15, 2007
AII amacrine cells (AIIACs) are crucial relay stations for rod-mediated signals in the mammalian retina and they receive synaptic inputs from depolarizing and hyperpolarizing bipolar cells (DBCs and HBCs) as well as from other amacrine cells. Using whole-c ...
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Journal ArticleInvest Ophthalmol Vis Sci · January 2007
PURPOSE: To investigate whether intravitreal Kenalog (IVTK; Bristol Meyers Squibb Company, Princeton, NJ) produces histologic or electroretinographic changes in the rabbit retina up to 3 months after injection. METHODS: Ten Dutch-belted rabbits were inject ...
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Journal ArticleHum Genet · September 2006
Bardet-Biedl syndrome (BBS) is a rare oligogenic disorder exhibiting both clinical and genetic heterogeneity. Although the BBS phenotype is variable both between and within families, the syndrome is characterized by the hallmarks of developmental and learn ...
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Journal ArticleGynecol Oncol · December 2005
OBJECTIVE: Structured illumination microscopy is an inexpensive alternative to confocal microscopy that allows optical sectioning at a sub-cellular resolution. However, its application in imaging biological tissue has been limited by inadequate contrast pr ...
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Journal ArticleIEEE Trans Biomed Eng · March 2003
The most common way to detect disease is by visual inspection of the suspect tissue. However, the human eye is not optimized for this task because the perceived spectrum of light is divided into three channels, all of which have overlapping spectral sensit ...
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ConferenceAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings · December 1, 2002
We describe the use of an optical sectioning wide-field microscope with an exogenous dye in order to improve the visualization of early oral cancer detection. We show positive results in imaging and optically sectioning turbid tissue phantoms stained with ...
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