Scholars@Duke
Jane Patricia Gagliardi

Jane Patricia Gagliardi

Professor of Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychology
Box 3488 Med Ctr, Durham, NC 27710
DUMC Box 3488, Durham, NC 27710

Selected Publications

Improving Behavioral Healthcare Access Disparities by Training Providers in Disadvantaged Communities - Evidence of Strategy Effectiveness.

Journal Article Journal of general internal medicine · January 2025 BackgroundInadequate access to behavioral health services disproportionately impacts marginalized populations who live in disadvantaged areas. To reduce this gap, programs dedicated to optimizing behavioral health education and training must focus ... Full text Cite

Championing Civility in the Clinical Learning Environment: Evaluation of a Novel Training Program.

Journal Article Acad Med · December 1, 2024 PROBLEM: Incivility in the health care workplace is increasing and negatively impacts everyone in the environment, including health care team members and the patients and families they serve. This study examined the efficacy and impact of Civility Champion ... Full text Link to item Cite

Racial and Ethnic Disparities in Patient Restraint in Emergency Departments by Police Transport Status.

Journal Article JAMA Netw Open · February 5, 2024 IMPORTANCE: Black patients are more likely than White patients to be restrained during behavioral crises in emergency departments (EDs). Although the perils of policing mental health for Black individuals are recognized, it is unclear whether or to what ex ... Full text Link to item Cite

Racial Inequities in Police Transport for Patients to the Emergency Department: A Multicenter Analysis.

Journal Article Am J Prev Med · January 2024 INTRODUCTION: Police involvement in patient transport to emergency medical care has increased over time, yet studies assessing racial inequities in transport are limited. This study evaluated the relationship between race and police transport to the emerge ... Full text Link to item Cite

Antidepressant Prescription Behavior Among Primary Care Clinician Providers After an Interprofessional Primary Care Psychiatric Training Program.

Journal Article Adm Policy Ment Health · November 2023 Primary care providers (PCPs) are increasingly called upon to screen for and treat depression. However, PCPs often lack the training to diagnose and treat depression. We designed an innovative 12-month evidence and mentorship-based primary care psychiatric ... Full text Link to item Cite

Experiences of Black Adults Evaluated in a Locked Psychiatric Emergency Unit: A Qualitative Study.

Journal Article Psychiatr Serv · October 1, 2023 OBJECTIVE: Evidence shows that Black individuals have higher rates of coercive emergency psychiatric interventions than other racialized groups, yet no studies have elevated the voices of Black patients undergoing emergency psychiatric evaluation. This qua ... Full text Link to item Cite

Eat More Copper?

Journal Article Am J Geriatr Psychiatry · October 2023 Full text Link to item Cite

A Multimedia Description of Catatonia Secondary to Anti-NMDA-Receptor Encephalitis.

Journal Article Prim Care Companion CNS Disord · September 26, 2023 Full text Link to item Cite

Integrated Care for Complicated Patients: A Role for Combined Training and Practice.

Journal Article Am J Geriatr Psychiatry · March 2023 Patients with chronic medical disease frequently have comorbid psychiatric illness, yet mental and physical healthcare is frequently siloed in the United States. Integrated behavioral healthcare models, such as medicine-psychiatry services, are feasible, i ... Full text Link to item Cite

In Reply to Farber et al.

Journal Article Acad Med · September 1, 2022 Full text Link to item Cite

Association of Black Race With Physical and Chemical Restraint Use Among Patients Undergoing Emergency Psychiatric Evaluation.

Journal Article Psychiatr Serv · July 2022 OBJECTIVE: Few studies have examined the disproportionate use of restraints for Black adults receiving emergency psychiatric care. This study sought to determine whether the odds of physical and chemical restraint use were higher for Black patients undergo ... Full text Link to item Cite

Medical Mistrust in Perinatal Mental Health.

Journal Article Harv Rev Psychiatry · July 2022 Despite the advancement of telemedicine and recent innovations in treatment, minoritized women continue to bear a disproportionate burden of pregnancy-related psychiatric conditions and complications, which the pandemic has further exacerbated. Research de ... Full text Link to item Cite

Combined Residency Programs in Psychiatry.

Journal Article Acad Psychiatry · June 2022 Full text Link to item Cite

Adaptation of the TEAM Mental Healthcare Delivery Model: A Mixed-Methods Evaluation.

Journal Article Issues Ment Health Nurs · March 2022 We report on the adaptation and evaluation of an existing approach to multicultural education into an eight-session online, modular curriculum for psychiatric mental health nurse practitioner students (n = 6) and psychology interns (n = 10). Training parti ... Full text Link to item Cite

What Can We Learn From Studies Linking Gout With Dementia?

Journal Article Am J Geriatr Psychiatry · December 2021 Full text Link to item Cite

Management of SIADH-related hyponatremia due to psychotropic medications - An expert consensus from the Association of Medicine and Psychiatry.

Journal Article J Psychosom Res · December 2021 OBJECTIVE: Hyponatremia is the most common electrolyte imbalance encountered in clinical practice and is associated with negative healthcare outcomes and cost. SIADH is thought to account for one third of all hyponatremia cases and is typically an insidiou ... Full text Link to item Cite

What Are the Data Really Telling Us About Systemic Racism?

Journal Article Am J Geriatr Psychiatry · October 2021 Full text Link to item Cite

Impact of physician names on missed appointments in psychiatry resident clinics: A pilot study

Journal Article Psychiatric Annals · October 1, 2021 The authors undertook the current study to investigate patient and provider factors and their relationship to patient show rates. The authors included as eligible all new patient appointments in psychiatry resident clinics at a large academic hospital-base ... Full text Cite

Implementation of Changes to Medical Student Documentation at Duke University Health System: Balancing Education With Service.

Journal Article Acad Med · June 1, 2021 PURPOSE: When the Centers for Medicare and Medicaid Services (CMS) changed policies about medical student documentation, students with proper supervision may now document their history, physical exam, and medical decision making in the electronic health re ... Full text Open Access Link to item Cite

Spirituality, Coping, and Resilience Among Rural Residents Living with Chronic Kidney Disease.

Journal Article J Relig Health · December 2020 Spirituality, an established resource within rural America, serves as an important coping mechanism for crises of chronic illness. We examined the effects of spirituality on chronic kidney disease (CKD) maintenance in the rural community of Robeson County, ... Full text Link to item Cite

QTc monitoring in adults with medical and psychiatric comorbidities: Expert consensus from the Association of Medicine and Psychiatry.

Journal Article J Psychosom Res · August 2020 OBJECTIVE: Several psychiatric medications have the potential to prolong the QTc interval and subsequently increase the risk for ventricular arrhythmias such as torsades de pointes (TdP). There is limited guidance for clinicians to balance the risks and be ... Full text Link to item Cite

Symptom-based patient stratification in mental illness using clinical notes.

Journal Article J Biomed Inform · October 2019 Mental illnesses are highly heterogeneous with diagnoses based on symptoms that are generally qualitative, subjective, and documented in free text clinical notes rather than as structured data. Moreover, there exists significant variation in symptoms withi ... Full text Link to item Cite

Translational bioinformatics in mental health: open access data sources and computational biomarker discovery.

Journal Article Brief Bioinform · May 21, 2019 Mental illness is increasingly recognized as both a significant cost to society and a significant area of opportunity for biological breakthrough. As -omics and imaging technologies enable researchers to probe molecular and physiological underpinnings of m ... Full text Link to item Cite

Discharge Plans for Geriatric Inpatients with Delirium: A Plan to Stop Antipsychotics?

Journal Article J Am Geriatr Soc · October 2017 BACKGROUND: Studies show inpatient geriatric patients with reversible conditions like delirium may continue on antipsychotic medications without clear indications after hospital discharge. We conducted this study to determine how often geriatric patients w ... Full text Link to item Cite

Development of a Diverse Learning Experience for Diverse Psychiatry Resident Needs: A Four-Year Biological Psychiatry Curriculum Incorporating Principles of Neurobiology, Psychopharmacology, and Evidence-Based Practice.

Journal Article Psychiatry Investig · May 2017 OBJECTIVE: A clinically relevant approach to patient care grounded in neurobiological constructs and evidence based practice which emphasizes a relevant psychopharmacology is needed to optimally train psychiatry residents. METHODS: We implemented a biologi ... Full text Link to item Cite

Teaching crucial skills: An electrocardiogram teaching module for medical students.

Journal Article J Electrocardiol · 2016 BACKGROUND: Medical student performance in electrocardiogram (ECG) interpretation at our institution could be improved. Varied resources exist to teach students this essential skill. METHODS: We created an ECG teaching module (ECGTM) of 75 cases representi ... Full text Link to item Cite

GME Concentrations: A Collaborative Interdisciplinary Approach to Learner-Driven Education.

Journal Article J Grad Med Educ · September 2015 BACKGROUND: Graduate medical education (GME) programs may struggle to provide the knowledge, skills, and experiences necessary to meet trainee career interests and goals beyond a clinical focus. Sponsoring institutions can partner with programs to deliver ... Full text Link to item Cite

Paraneoplastic Encephalopathy Presenting with Rapidly Progressive Dementia and Catatonia

Conference The American Journal of Geriatric Psychiatry · March 2015 Full text Cite

Evaluation of Changes in Citalopram Prescribing Patterns Following a US Food and Drug Administration Alert: A Retrospective Cohort Study.

Journal Article Prim Care Companion CNS Disord · 2015 OBJECTIVE: The US Food and Drug Administration (FDA) issued a warning stating that patients older than 60 years are not recommended to receive doses of citalopram exceeding 20 mg daily due to concerns of corrected QT (QTc) prolongation. The purpose of this ... Full text Link to item Cite

Defining the Role of Dexmedetomidine in the Prevention of Delirium in the Intensive Care Unit.

Journal Article Biomed Res Int · 2015 Dexmedetomidine is a highly selective α 2 agonist used as a sedative agent. It also provides anxiolysis and sympatholysis without significant respiratory compromise or delirium. We conducted a systematic review to examine whether sedation of patients in th ... Full text Link to item Cite

Use of diuretics is associated with reduced risk of Alzheimer's disease: the Cache County Study.

Journal Article Neurobiol Aging · November 2014 Although the use of antihypertensive medications has been associated with reduced risk of Alzheimer's disease (AD), it remains unclear which class provides the most benefit. The Cache County Study of Memory Health and Aging is a prospective longitudinal co ... Full text Link to item Cite

Dexmedetomidine for the treatment of alcohol withdrawal syndrome: rationale and current status of research.

Journal Article CNS Drugs · November 2013 Dexmedetomidine is currently used in the US in the treatment of alcohol withdrawal syndrome (AWS) in the intensive care unit (ICU) setting, although data to support this practice are limited. Dexmedetomidine targets the noradrenergic system, an important b ... Full text Link to item Cite

Clinical effectiveness of baclofen for the treatment of alcohol dependence: a review.

Journal Article Clin Pharmacol · 2013 Baclofen, an agonist at the B subunit of gaba-aminobutyric acid receptor, possesses pharmacologic properties that may confer utility for the treatment of alcohol dependence. Research suggests that not only can it be useful in promoting maintenance of alcoh ... Full text Link to item Cite

A computerized physician order entry set designed to improve safety of intravenous haloperidol utilization: a retrospective study in agitated hospitalized patients.

Journal Article Drug Saf · September 1, 2012 BACKGROUND: Intravenous haloperidol can increase the risk for corrected QT (QTc) interval prolongation, torsades de pointes (TdP) and sudden death. OBJECTIVE: The purpose of this study was to examine the effects of implementation of a computerized physicia ... Full text Link to item Cite

Examination of baseline risk factors for QTc interval prolongation in patients prescribed intravenous haloperidol.

Journal Article Drug Saf · July 1, 2012 BACKGROUND: Intravenous haloperidol can increase the risk for corrected QT interval (QTc) prolongation, torsades de pointes (TdP) and sudden death. There are a number of risk factors reported in the literature for QTc prolongation and TdP with intravenous ... Full text Link to item Cite

Prevalence of baseline lipid monitoring in patients prescribed second-generation antipsychotics during their index hospitalization: a retrospective cohort study.

Journal Article Gen Hosp Psychiatry · 2012 BACKGROUND: Second-generation antipsychotics have been found to increase a patient's risk of dyslipidemia. Despite consensus statement recommendations for lipid monitoring, studies indicate that up to 90% of patients still do not have a baseline lipid pane ... Full text Link to item Cite

Defining the role of baclofen for the treatment of alcohol dependence: a systematic review of the evidence.

Journal Article CNS Drugs · January 1, 2012 The pharmacological properties of baclofen, a GABA(B) receptor agonist, have led to investigation of its use for the off-label treatment of alcohol dependence. Literature examining the role of baclofen in alcohol dependence suggests that it may be a useful ... Full text Link to item Cite

Use of aripiprazole in a patient with multiple sclerosis presenting with paranoid psychosis.

Journal Article J Psychiatr Pract · November 2010 Featured Publication Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder of the central nervous system (CNS). A significant percentage of MS patients will develop neuropsychiatric symptoms during their lifetime; affective symptoms are most common, but psychosis ... Full text Link to item Cite

Beta-blockers and depression.

Journal Article Am J Psychiatry · February 2010 Featured Publication Full text Link to item Cite

Behavioral observations reflected on consultation requests from primary medical-surgical services: are they predictive of delirium diagnosis and outcomes?

Journal Article J Psychosom Res · February 2009 Featured Publication OBJECTIVE: We studied 405 patients evaluated by the Psychosomatics Service to investigate whether the behavioral description as reflected on consultation request from primary medical-surgical teams could be utilized to predict the final clinical diagnosis ... Full text Link to item Cite

Point and 5-year period prevalence of neuropsychiatric symptoms in dementia: the Cache County Study.

Journal Article Int J Geriatr Psychiatry · February 2008 BACKGROUND: Neuropsychiatric symptoms are nearly universal in dementia, yet little is known about their longitudinal course in the community. OBJECTIVE: To estimate point and 5-year period prevalence of neuropsychiatric symptoms in an incident sample of 40 ... Full text Link to item Cite

Autopsy-confirmed Alzheimer's disease versus clinically diagnosed Alzheimer's disease in the Cache County Study on Memory and Aging: a comparison of quantitative MRI and neuropsychological findings.

Journal Article J Clin Exp Neuropsychol · July 2007 Atrophy of specific, regional, and generalized brain structures occurs as a result of the Alzheimer's disease (AD) process. Comparing AD patients with histopathological confirmation of the disease at autopsy to those without autopsy but who were clinically ... Full text Link to item Cite

Sertaline for the Prevention of Depression with HCV Therapy

Conference American Journal of Gastroenterology · September 2006 Full text Cite

Drugs for percutaneous coronary interventions.

Journal Article Med Lett Drugs Ther · December 6, 2004 Many combinations of anticoagulants and antiplatelet drugs have been used to treat patients undergoing a percutaneous coronary intervention (PCI). Among anticoagulants, enoxaparin has some theoretical advantages over unfractionated heparin, but in clinical ... Link to item Cite

L-carnitine.

Journal Article Med Lett Drugs Ther · November 22, 2004 Although advertised on the Internet for weight loss, prevention of aging and enhancement of athletic and sexual performance, levocarnitine has only one well-established indication, and that is for treatment of carnitine deficiency. In clinical trials, the ... Link to item Cite

Systemic reactions to imiquimod (Aldara).

Journal Article Med Lett Drugs Ther · November 8, 2004 Link to item Cite

What about celebrex?

Journal Article Med Lett Drugs Ther · October 25, 2004 Link to item Cite

Influenza vaccine 2004-2005.

Journal Article Med Lett Drugs Ther · October 11, 2004 Link to item Cite

Cinacalcet (Sensipar)

Journal Article Medical Letter on Drugs and Therapeutics · September 27, 2004 Cinacalcet, an oral drug that decreases release of parathyroid hormone, can lower serum calcium concentrations in patients with secondary hyperparathyroidism or parathyroid carcinoma. ... Cite

Botulinum toxin (Botox) for axillary hyperhidrosis.

Journal Article Med Lett Drugs Ther · September 13, 2004 Link to item Cite

Menostar - a low-dose estrogen patch for osteoporosis.

Journal Article Med Lett Drugs Ther · August 30, 2004 Link to item Cite

Atomoxetine (Strattera) revisited.

Journal Article Med Lett Drugs Ther · August 16, 2004 Link to item Cite

Do NSAIDs interfere with the cardioprotective effects of aspirin?

Journal Article Med Lett Drugs Ther · August 2, 2004 Link to item Cite

Performance-enhancing drugs.

Journal Article Med Lett Drugs Ther · July 19, 2004 Link to item Cite

Initial therapy of hypertension.

Journal Article Med Lett Drugs Ther · July 5, 2004 Link to item Cite

Conductive keratoplasty (CK) for presbyopia.

Journal Article Med Lett Drugs Ther · June 21, 2004 Link to item Cite

Prevention and treatment of sunburn.

Journal Article Med Lett Drugs Ther · June 7, 2004 Link to item Cite

Tiotropium (Spiriva) for COPD.

Journal Article Med Lett Drugs Ther · May 24, 2004 Link to item Cite

Cholesterol rethink for high-risk patients.

Journal Article Med Lett Drugs Ther · May 10, 2004 Link to item Cite

NovoSeven for non-hemophilia hemostasis.

Journal Article Med Lett Drugs Ther · April 26, 2004 Link to item Cite

Evidence-based mental health use of anticonvulsants during pregnancy.

Journal Article Psychopharmacol Bull · 2003 There are many pertinent issues surrounding the treatment of bipolar disorder during pregnancy. Unfortunately, while there are numerous observational reports in the literature, there is not a lot of information concerning the safety and efficacy of particu ... Link to item Cite

Evidence for the treatment of borderline personality disorder.

Journal Article Psychopharmacol Bull · 2003 The treatment of patients with borderline personality disorder (BPD) is notoriously difficult. Psychotherapeutic and pharmacological strategies have been investigated, and a few have shown promise. Dialectical behavior therapy (DBT) may be helpful in decre ... Link to item Cite

Treatment of thyrotoxicosis-induced psychosis.

Journal Article Psychopharmacol Bull · 2002 Link to item Cite

Native valve infective endocarditis in elderly and younger adult patients: comparison of clinical features and outcomes with use of the Duke criteria and the Duke Endocarditis Database.

Journal Article Clin Infect Dis · May 1998 The effect of age on the presentation and outcome of infective endocarditis (IE) is unclear. Many of the available data are based on analyses of mixed populations of patients including intravenous drug users or those with prosthetic valve endocarditis or n ... Full text Link to item Cite