Scholars@Duke
Hakim Azfar Ali

Hakim Azfar Ali

Associate Professor of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
hakim.azfarali@duke.edu
Room 120 Hanes Hse, Box 102352, Durham, NC 27710
330 Trent Drive, DUMC 102352, Durham, NC 27710

Selected Publications

Passenger Lymphocyte Syndrome Presenting With Severe Refractory Thrombocytopenia After Transplantation: A Multi-Recipient Case Series.

Journal Article Clin Transplant · September 2025 Passenger lymphocyte syndrome (PLS) is an immune-mediated complication that can occur following solid organ transplantation, resulting from the transfer of donor-derived lymphocytes that produce alloantibodies targeting recipient antigens. We report a case ... Full text Link to item Cite

Postoperative Lung Transplant Considerations in the Older Recipient.

Journal Article Chest · August 2025 TOPIC IMPORTANCE: Lung transplantation (LTx) remains the ultimate treatment for many patients with advanced lung disease. Although the age cutoffs for LTx have been debated due to variable outcomes, the number of LTx procedures performed on patients aged ≥ ... Full text Link to item Cite

Inadequate (Ax) Transbronchial Lung Transplant Biopsies-Scope and the Potential Contributing Factors.

Journal Article Transplant Proc · 2024 BACKGROUND: Transbronchial biopsy is the cornerstone for the evaluation of graft function after lung transplant and a standard of care to diagnose acute cellular rejection. However, the yield from these biopsies is variable, with about 15% to 50% of sample ... Full text Link to item Cite

Development of New Donor-Specific and Human Leukocyte Antigen Antibodies After Transfusion in Adult Lung Transplantation.

Journal Article J Cardiothorac Vasc Anesth · September 2023 OBJECTIVES: The development of new human leukocyte antigens (HLAs) and donor-specific antibodies (DSAs) in patients are associated with worse outcomes following lung transplantation. The authors aimed to examine the relationship between blood product trans ... Full text Open Access Link to item Cite

(1175) Gaps in Lung Transplant Training Curriculum in North America

Journal Article The Journal of Heart and Lung Transplantation · April 2023 Full text Cite

Impact of Tacrolimus Trough Variability on Acute Rejection Following Lung Transplantation.

Journal Article Transplant Proc · October 2022 BACKGROUND: Acute rejection is a risk factor for the development of chronic lung allograft dysfunction, the leading cause of morbidity and mortality in lung transplant recipients. Calcineurin inhibitors are the cornerstone of immunosuppression regimens aft ... Full text Link to item Cite

Complications of Lung Transplantation: Update on Imaging Manifestations and Management.

Journal Article Radiol Cardiothorac Imaging · August 2021 As lung transplantation has become the most effective definitive treatment option for end-stage chronic respiratory diseases, yearly rates of this surgery have been steadily increasing. Despite improvement in surgical techniques and medical management of t ... Full text Link to item Cite

Lung Transplantation and the Era of the Sensitized Patient.

Journal Article Front Immunol · 2021 Long term outcomes in lung transplant are limited by the development of chronic lung allograft dysfunction (CLAD). Within the past several decades, antibody-mediated rejection (AMR) has been recognized as a risk factor for CLAD. The presence of HLA antibod ... Full text Open Access Link to item Cite

An Uncommon Clue - Pneumocystis Pneumonia in a Lung Transplant Patient Presenting with Hypercalcemia

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Link to item Cite

Complement system in lung transplantation.

Journal Article Clin Transplant · April 2018 The complement system is a cascade of multiple proteins that have been known to mediate inflammatory response. This tightly regulated system has been recognized to play a role in adaptive immunity via humoral and cell-mediated processes. There is evidence ... Full text Link to item Cite

Rejection after Lung Transplantation?

Journal Article American Journal of Respiratory and Critical Care Medicine · May 15, 2016 Full text Cite

Polymicrobial Sepsis Related To Strongyloides Infection In A Lung Transplant Recipient

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2015 Link to item Cite

High Dose Brachytherapy For Bronchial Stenosis In Lung Transplant Recipients

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2015 Link to item Cite

The competence debate.

Journal Article Chest · February 2014 Full text Link to item Cite

Respiratory failure due to achalasia cardia

Journal Article Respiratory Medicine CME · March 6, 2009 A 76-year-old male was seen in our hospital for hypoxic respiratory failure and bronchorrhea worsening over a few weeks. He failed treatment with antibiotics and diuretics. A CT scan of the chest was performed which revealed a dilated esophagus with an air ... Full text Cite

Clinical features of thymus pathology

Chapter · December 1, 2008 Thymus pathology embraces a broad spectrum of features, varying from major immunologic abnormalities affecting all organ systems to minor abnormalities with limited clinical consequences. Some individuals with thymus pathology may have all the features of ... Full text Cite

Respiratory failure due to achalasia cardia

Journal Article Respiratory Medicine CME · September 30, 2008 Full text Cite

Omega-3 fatty acids in cardiac biopsies from heart transplantation patients: correlation with erythrocytes and response to supplementation.

Journal Article Circulation · September 21, 2004 BACKGROUND: Omega-3 fatty acids (FAs) appear to reduce the risk of sudden death from myocardial infarction. This reduction is believed to occur via the incorporation of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) into the myocardium itself, ... Full text Link to item Cite

Congenital erythropoietic porphyria (Gunther's disease) presenting as anterior Staphyloma and blindness

Journal Article JK Practitioner · December 1, 2001 Photographs and brief write up of CEP is presented in view of its rarity alongwith a description of this interesting condition and review of literature. CEP is a rare disease, inherited in an autosomal recessive fashion in which the eye is effected not so ... Cite