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Jane Frances Pendergast

Professor Emeritus of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
Duke Box 2721, Durham, NC 27710
2424 Erwin Road Ste 1105, 11043 Hock Plaza, Durham, NC 27705

Selected Publications


Breast and Prostate Cancer Screening by Life Expectancy in Patients with Kidney Failure on Dialysis.

Journal Article Clin J Am Soc Nephrol · December 1, 2024 KEY POINTS: Breast and prostate cancer screening were more frequent among patients on hemodialysis waitlisted for kidney transplant. Among patients not waitlisted for transplant, we found that screening rates were generally higher among patients with highe ... Full text Link to item Cite

Assessing Fears of Negative Consequences in Children With Symptoms of Avoidant Restrictive Food Intake Disorder.

Journal Article Int J Eat Disord · November 8, 2024 OBJECTIVE: Fear of Aversive Consequences (FOAC), such as choking or vomiting, is an important associated feature of Avoidant/Restrictive Food Intake Disorder (ARFID). However, the manifestation of FOAC in young children is poorly understood. This study aim ... Full text Link to item Cite

Association of Coprescribing of Gabapentinoid and Other Psychoactive Medications With Altered Mental Status and Falls in Adults Receiving Dialysis.

Journal Article Am J Kidney Dis · October 3, 2024 RATIONALE & OBJECTIVE: Prescribing psychoactive medications for patients with kidney disease is common, but for patients receiving dialysis some medications may be inappropriate. We evaluated the association of coprescribing gabapentinoids and other psycho ... Full text Link to item Cite

Clinical Outcomes Among High-Risk Primary Care Patients With Diabetic Kidney Disease: Methodological Challenges and Results From the STOP-DKD Study.

Journal Article Med Care · October 1, 2024 BACKGROUND/OBJECTIVE: Slowing the progression of diabetic kidney disease (DKD) is critical. We conducted a randomized controlled trial to target risk factors for DKD progression. METHODS: We evaluated the effect of a pharmacist-led intervention focused on ... Full text Open Access Link to item Cite

Small Monetary Incentives Lead to Greater Adherence in a Weight Loss Program.

Journal Article Am J Health Promot · February 2024 PURPOSE: Understand how weekly monetary incentives for dietary tracking and/or weight loss impact 6-month weight loss behavioral adherence. DESIGN: Secondary analysis of participants randomized to one of four conditions in a behavioral weight loss interven ... Full text Link to item Cite

Comparative Effectiveness of Alternative Treatment Approaches to Secondary Hyperparathyroidism in Patients Receiving Maintenance Hemodialysis: An Observational Trial Emulation.

Journal Article Am J Kidney Dis · January 2024 RATIONALE & OBJECTIVE: Optimal approaches to treat secondary hyperparathyroidism (SHPT) in patients on maintenance hemodialysis (HD) have yet to be established in randomized controlled trials (RCTs). STUDY DESIGN: Two observational clinical trial emulation ... Full text Link to item Cite

Incidence of Kidney Failure after Primary Organ Transplant.

Journal Article Kidney360 · January 1, 2024 KEY POINTS: Incidence of ESKD in the first year after primary organ transplant ranges from 2.4% to 3.6% and from 1.4% to 1.8% in the second year post-transplant. National data sources do not currently collect sufficiently reliable follow-up data to identif ... Full text Link to item Cite

Received Self-Care Support and Psychosocial Health Among Older Adults with Non-Dialysis-Dependent Chronic Kidney Disease.

Journal Article Nephrol Nurs J · 2024 Older age is linked with poorer self-care in the chronic kidney disease (CKD) setting. Informal health supporters (family members and friends) are critical sources of self-care support, but much remains unclear about the characteristics and implications of ... Link to item Cite

Racial Equity in Living Donor Kidney Transplant Centers, 2008-2018.

Journal Article JAMA Netw Open · December 1, 2023 IMPORTANCE: It is unclear whether center-level factors are associated with racial equity in living donor kidney transplant (LDKT). OBJECTIVE: To evaluate center-level factors and racial equity in LDKT during an 11-year time period. DESIGN, SETTING, AND PAR ... Full text Link to item Cite

Comparison of weight captured via electronic health record and cellular scales to the gold-standard clinical method.

Journal Article Obes Sci Pract · August 2023 INTRODUCTION: Obtaining body weights remotely could improve feasibility of pragmatic trials. This investigation examined whether weights collected via cellular scale or electronic health record (EHR) correspond to gold standard in-person study weights. MET ... Full text Link to item Cite

Exploration of model misspecification in latent class methods for longitudinal data: Correlation structure matters.

Journal Article Statistics in medicine · June 2023 Modeling longitudinal trajectories and identifying latent classes of trajectories is of great interest in biomedical research, and software to identify latent classes of such is readily available for latent class trajectory analysis (LCTA), growth mixture ... Full text Cite

A comparison of deprivation indices and application to transplant populations.

Journal Article Am J Transplant · March 2023 The choice of deprivation index can influence conclusions drawn regarding the extent of deprivation within a community and the identification of the most deprived communities in the United States. This study aimed to determine the degree of correlation amo ... Full text Link to item Cite

Goal-Concordance in Children with Complex Chronic Conditions.

Journal Article J Pediatr · February 2023 OBJECTIVES: To characterize delivery of goal-concordant end-of-life (EOL) care among children with complex chronic conditions and to determine factors associated with goal-concordance. STUDY DESIGN: This was a retrospective review of goals of care discussi ... Full text Link to item Cite

Identification of Trajectory-Based Acute Kidney Injury Phenotypes Among Cardiac Surgery Patients.

Journal Article Ann Thorac Surg · December 2022 BACKGROUND: Acute kidney injury (AKI) is a common and serious complication of cardiac surgical procedures for which unrecognized heterogeneity may underpin poor success in identifying effective therapies. We aimed to identify phenotypically similar groups ... Full text Link to item Cite

No Quick Fixes: Integrating Population Health Education and Quality Improvement in a Large Residency Program.

Journal Article J Healthc Qual · September 2022 The intersection of population health (PH), quality improvement (QI), and health disparities is increasingly a focus in graduate medical education. However, it remains unclear how trainees may best improve disparities within clinical training environments. ... Full text Link to item Cite

Geospatial Analysis of Organ Transplant Referral Regions.

Journal Article JAMA Netw Open · September 1, 2022 IMPORTANCE: System and center-level interventions to improve health equity in organ transplantation benefit from robust characterization of the referral population served by each transplant center. Transplant referral regions (TRRs) define geographic catch ... Full text Link to item Cite

Bioavailability of phosphorus and kidney function in the Jackson Heart Study.

Journal Article Am J Clin Nutr · August 4, 2022 BACKGROUND: High phosphorus (P) exposure may have negative effects on kidney function. Nutrient databases provide total P, but bioavailability varies by source. OBJECTIVES: We aimed to assess natural, added, and bioavailable P intake, and to relate these t ... Full text Link to item Cite

Implementation of a telehealth videoconference to improve hospital-to-skilled nursing care transitions: Preliminary data.

Journal Article J Am Geriatr Soc · June 2022 BACKGROUND: Transition-related patient safety errors are high among patients discharged from hospitals to skilled nursing facilities (SNFs), and interventions are needed to improve communication between hospitals and SNF providers. Our objective was to des ... Full text Link to item Cite

Perceptions of Exercise and Its Challenges in Patients With Nonalcoholic Fatty Liver Disease: A Survey-Based Study.

Journal Article Hepatol Commun · February 2022 Exercise is a foundational treatment for nonalcoholic fatty liver disease (NAFLD); however, the majority of patients are unable to initiate and maintain effective exercise habits and remain at increased risk for progressive liver disease. Barriers and limi ... Full text Link to item Cite

Psychosocial determinants of cardiovascular events among black Americans with chronic kidney disease or associated risk factors in the Jackson heart study.

Journal Article BMC Nephrol · November 11, 2021 BACKGROUND: Individuals with chronic kidney disease (CKD), hypertension (HTN), or diabetes mellitus (DM) are at increased risk for cardiovascular disease (CVD). The extent to which psychosocial factors are associated with increased CVD risk within these in ... Full text Link to item Cite

Effect of Bicarbonate on Net Acid Excretion, Blood Pressure, and Metabolism in Patients With and Without CKD: The Acid Base Compensation in CKD Study.

Journal Article Am J Kidney Dis · July 2021 RATIONALE & OBJECTIVE: Patients with CKD are at elevated risk of metabolic acidosis due to impaired net acid excretion (NAE). Identifying early markers of acidosis may guide prevention in chronic kidney disease (CKD). This study compared NAE in participant ... Full text Link to item Cite

Risks associated with continuation of potentially inappropriate antihypertensive medications in older adults receiving hemodialysis.

Journal Article BMC Nephrol · June 19, 2021 BACKGROUND AND OBJECTIVES: After dialysis initiation, older adults may experience orthostatic or post-dialysis hypotension. Some orthostasis-causing antihypertensives (i.e., central alpha agonists and alpha blockers), are considered potentially inappropria ... Full text Link to item Cite

Transplant social worker and donor financial assistance to increase living donor kidney transplants among African Americans: The TALKS Study, a randomized comparative effectiveness trial.

Journal Article Am J Transplant · June 2021 Lack of donors hinders living donor kidney transplantation (LDKT) for African Americans. We studied the effectiveness of a transplant social worker intervention (TALK SWI) alone or paired with living donor financial assistance to activate African Americans ... Full text Link to item Cite

Targeting Patient and Health System Barriers To Improve Rates of Hemodialysis Initiation with an Arteriovenous Access.

Journal Article Kidney360 · April 29, 2021 BACKGROUND: Guidelines recommend pre-emptive creation of arteriovenous (AV) access. However, <20% of US patients initiate hemodialysis (HD) with a functional AV access. We implemented a quality improvement (QI) program to improve pre-HD vascular access car ... Full text Link to item Cite

A randomized feasibility pilot trial of a financial incentives intervention for dietary self-monitoring and weight loss in adults with obesity.

Journal Article Transl Behav Med · April 26, 2021 Financial incentives could be used to improve adherence to behavioral weight loss interventions, increasing their effectiveness. This Phase IIb randomized pilot study evaluated the feasibility and acceptability of a study protocol for providing financial i ... Full text Link to item Cite

Statins and atherosclerotic cardiovascular outcomes in patients on incident dialysis and with atherosclerotic heart disease.

Journal Article Am Heart J · January 2021 UNLABELLED: Statins failed to reduce cardiovascular (CV) events in trials of patients on dialysis. However, trial populations used criteria that often excluded those with atherosclerotic heart disease (ASHD), in whom statins have the greatest benefit, and ... Full text Link to item Cite

Integrated Digital Health System Tools to Support Decision Making and Treatment Preparation in CKD: The PREPARE NOW Study.

Journal Article Kidney Med · 2021 RATIONALE & OBJECTIVE: Digital health system tools to support shared decision making and preparation for kidney replacement treatments for patients with chronic kidney disease (CKD) are needed. STUDY DESIGN: Descriptive study of the implementation of digit ... Full text Link to item Cite

Preferences for and Experiences of Shared and Informed Decision Making Among Patients Choosing Kidney Replacement Therapies in Nephrology Care.

Journal Article Kidney Med · 2021 RATIONALE & OBJECTIVE: Chronic kidney disease (CKD) can progress rapidly, and patients are often unprepared to make kidney failure treatment decisions. We aimed to better understand patients' preferences for and experiences of shared and informed decision ... Full text Link to item Cite

Trends in Mineral Metabolism Treatment Strategies in Patients Receiving Hemodialysis in the United States.

Journal Article Clin J Am Soc Nephrol · November 6, 2020 BACKGROUND AND OBJECTIVES: With multiple medications indicated for mineral metabolism, dialysis providers can apply various strategies to achieve target phosphate and parathyroid hormone (PTH) levels. We describe common prescribing patterns and practice va ... Full text Link to item Cite

Racial Differences in the Effectiveness of a Multifactorial Telehealth Intervention to Slow Diabetic Kidney Disease.

Journal Article Med Care · November 2020 BACKGROUND: African Americans are significantly more likely than non-African Americans to have diabetes, chronic kidney disease, and uncontrolled hypertension, increasing their risk for kidney function decline. OBJECTIVE: The objective of this study was to ... Full text Open Access Link to item Cite

Life Course Socioeconomic Status, Allostatic Load, and Kidney Health in Black Americans.

Journal Article Clin J Am Soc Nephrol · March 6, 2020 BACKGROUND AND OBJECTIVES: Low socioeconomic status confers unfavorable health, but the degree and mechanisms by which life course socioeconomic status affects kidney health is unclear. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We examined the associa ... Full text Link to item Cite

Associations of perceived information adequacy and knowledge with pursuit of live donor kidney transplants and living donor inquiries among African American transplant candidates.

Journal Article Clin Transplant · March 2020 We studied associations between perceived adequacy of live donor kidney transplant (LDKT) information or knowledge with pursuit of LDKT or receipt of live donor inquiries among 300 African American kidney transplant candidates. Participants reported via qu ... Full text Link to item Cite

Hypertension Self-management in Socially Disadvantaged African Americans: the Achieving Blood Pressure Control Together (ACT) Randomized Comparative Effectiveness Trial.

Journal Article J Gen Intern Med · January 2020 BACKGROUND: Effective hypertension self-management interventions are needed for socially disadvantaged African Americans, who have poorer blood pressure (BP) control compared to others. OBJECTIVE: We studied the incremental effectiveness of contextually ad ... Full text Link to item Cite

Multiyear Outcomes of a Population-Oriented Care Redesign in an Internal Medicine Residency Continuity Clinic.

Journal Article J Health Care Poor Underserved · 2020 The cornerstone of ambulatory care training for internal medicine residents is the continuity clinic, which often serves medically and psychosocially complex patients. We conducted and evaluated a population-oriented redesign to improve care for "high-need ... Full text Link to item Cite

Advanced CKD Care and Decision Making: Which Health Care Professionals Do Patients Rely on for CKD Treatment and Advice?

Journal Article Kidney Med · 2020 RATIONALE & OBJECTIVE: Chronic kidney disease (CKD) care is often fragmented across multiple health care providers. It is unclear whether patients rely mostly on their nephrologists or non-nephrologist providers for medical care, including CKD treatment an ... Full text Link to item Cite

DASH Diet and Blood Pressure Among Black Americans With and Without CKD: The Jackson Heart Study.

Journal Article Am J Hypertens · September 24, 2019 BACKGROUND: The Dietary Approaches to Stop Hypertension (DASH) diet lowers blood pressure (BP) more effectively in blacks compared to other US racial subgroups. Considering chronic kidney disease (CKD) raises BP through complex mechanisms, DASH may affect ... Full text Link to item Cite

Predictors of Net Acid Excretion in the Chronic Renal Insufficiency Cohort (CRIC) Study.

Journal Article Am J Kidney Dis · August 2019 RATIONALE & OBJECTIVE: Higher urine net acid excretion (NAE) is associated with slower chronic kidney disease progression, particularly in patients with diabetes mellitus. To better understand potential mechanisms and assess modifiable components, we explo ... Full text Link to item Cite

Association of functional and structural social support with chronic kidney disease among African Americans: the Jackson Heart Study.

Journal Article BMC Nephrol · July 15, 2019 BACKGROUND: There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD) and kidney function decline in an ... Full text Link to item Cite

Modifiers of Plasma 25-Hydroxyvitamin D and Chronic Kidney Disease Outcomes in Black Americans: The Jackson Heart Study.

Internet Publication · June 1, 2019 BACKGROUND: 25-hydroxyvitamin D [25(OH)D] is lower in black compared with white Americans but is not consistently associated with outcomes in this group, possibly due to genetic and other biological differences. We examined the association of plasma 25(OH) ... Full text Open Access Link to item Cite

Addressing Diabetes and Poorly Controlled Hypertension: Pragmatic mHealth Self-Management Intervention.

Journal Article J Med Internet Res · April 9, 2019 BACKGROUND: Patients with diabetes and poorly controlled hypertension are at increased risk for adverse renal and cardiovascular outcomes. Identifying these patients early and addressing modifiable risk factors is central to delaying renal complications su ... Full text Open Access Link to item Cite

Development of a Telehealth Intervention to Improve Access to Live Donor Kidney Transplantation.

Journal Article Transplant Proc · April 2019 BACKGROUND: Live donor kidney transplantation (LDKT) is underutilized by patients with end-stage kidney disease due to knowledge, communication, and logistical barriers. MATERIAL AND METHODS: The Talking About Live Kidney Donation Social Worker Interventio ... Full text Link to item Cite

Smoking Status and Survival Among a National Cohort of Lung and Colorectal Cancer Patients.

Journal Article Nicotine Tob Res · March 30, 2019 INTRODUCTION: The purpose of this study was to explore the association of smoking status and clinically relevant duration of smoking cessation with long-term survival after lung cancer (LC) or colorectal cancer (CRC) diagnosis. We compared survival of pati ... Full text Link to item Cite

The Role of Expert Judgment in Statistical Inference and Evidence-Based Decision-Making

Journal Article American Statistician · March 29, 2019 This article resulted from our participation in the session on the ā€œrole of expert opinion and judgment in statistical inferenceā€ at the October 2017 ASA Symposium on Statistical Inference. We present a strong, unified statement on roles of expert judgment ... Full text Cite

Evaluation of Allostatic Load as a Mediator of Sleep and Kidney Outcomes in Black Americans.

Journal Article Kidney Int Rep · March 2019 INTRODUCTION: Poor sleep associates with adverse chronic kidney disease (CKD) outcomes yet the biological mechanisms underlying this relation remain unclear. One proposed mechanism is via allostatic load, a cumulative biologic measure of stress. METHODS: U ... Full text Open Access Link to item Cite

Log2Lose: Development and Lessons Learned From a Mobile Technology Weight Loss Intervention.

Journal Article JMIR Mhealth Uhealth · February 13, 2019 BACKGROUND: Providing financial incentives has gained popularity as a strategy to promote weight loss, but questions remain about how best to utilize them. A promising mobile health strategy provides users with near-real-time financial incentives based on ... Full text Link to item Cite

Dietary Phosphorus and Ambulatory Blood Pressure in African Americans: The Jackson Heart Study.

Journal Article Am J Hypertens · January 1, 2019 BACKGROUND: Higher dietary phosphorus is associated with left ventricular hypertrophy and mortality, which are blood pressure (BP)-related outcomes. For this reason, we hypothesized that dietary phosphorus may be associated with adverse clinic and ambulato ... Full text Link to item Cite

Self-reported Physical Function Decline and Mortality in Older Adults Receiving Hemodialysis.

Journal Article Kidney Med · 2019 RATIONALE & OBJECTIVE: Timely recognition of functional decline in older adults receiving dialysis will allow clinicians to pursue interventions to prevent further disability and/or lead patient-centered goals of care discussions. Annual change in the 12-I ... Full text Link to item Cite

Trends in African Americans' Attitudes and Behaviors About Living Donor Kidney Transplantation.

Journal Article Prog Transplant · December 2018 BACKGROUND: Due to marginal efforts to increase living donor kidney transplantation, it is unclear whether interventions to improve African Americans' interest and pursuit of living donation should be tailored to address patients' exposure to or familiarit ... Full text Link to item Cite

Putting patients at the center of kidney care transitions: PREPARE NOW, a cluster randomized controlled trial.

Journal Article Contemp Clin Trials · October 2018 UNLABELLED: Care for patients transitioning from chronic kidney disease to kidney failure often falls short of meeting patients' needs. The PREPARE NOW study is a cluster randomized controlled trial studying the effectiveness of a pragmatic health system i ... Full text Link to item Cite

12-month trajectories of depressive symptoms among nurses-Contribution of personality, job characteristics, coping, and burnout.

Journal Article J Affect Disord · July 2018 BACKGROUND: Job related factors have been associated with higher risk for developing depression, but past studies lacked full consideration of individual factors such as personality and coping. We sought to evaluate associations of personality, coping, job ... Full text Link to item Cite

Obesity and synergistic risk factors for chronic kidney disease in African American adults: the Jackson Heart Study.

Journal Article Nephrol Dial Transplant · June 1, 2018 BACKGROUND: African Americans are at high risk for chronic kidney disease (CKD). Obesity may increase the risk for CKD by exacerbating features of the metabolic syndrome and promoting glomerular hyperfiltration. Whether other factors also affecting these p ... Full text Link to item Cite

Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) study: Protocol and baseline characteristics of a randomized controlled trial.

Journal Article Contemp Clin Trials · June 2018 UNLABELLED: Diabetic kidney disease (DKD) is the leading cause of end-stage kidney disease (ESKD) in the United States. Multiple risk factors contribute to DKD development, yet few interventions target more than a single DKD risk factor at a time. This man ... Full text Open Access Link to item Cite

Nondepressive Psychosocial Factors and CKD Outcomes in Black Americans.

Journal Article Clin J Am Soc Nephrol · February 7, 2018 BACKGROUND AND OBJECTIVES: Established risk factors for CKD do not fully account for risk of CKD in black Americans. We studied the association of nondepressive psychosocial factors with risk of CKD in the Jackson Heart Study. DESIGN, SETTING, PARTICIPANTS ... Full text Link to item Cite

Study protocol for Log2Lose: A feasibility randomized controlled trial to evaluate financial incentives for dietary self-monitoring and interim weight loss in adults with obesity.

Journal Article Contemp Clin Trials · February 2018 The obesity epidemic has negative physical, psychological, and financial consequences. Despite the existence of effective behavioral weight loss interventions, many individuals do not achieve adequate weight loss, and most regain lost weight in the year fo ... Full text Link to item Cite

Racial differences in nocturnal dipping status in diabetic kidney disease: Results from the STOP-DKD (Simultaneous Risk Factor Control Using Telehealth to Slow Progression of Diabetic Kidney Disease) study.

Journal Article J Clin Hypertens (Greenwich) · December 2017 While racial variation in ambulatory blood pressure (BP) is known, patterns of diurnal dipping in the context of diabetic kidney disease have not been well defined. The authors sought to determine the association of race with nocturnal dipping status among ... Full text Open Access Link to item Cite

Physical resilience of older cancer survivors: An emerging concept.

Journal Article J Geriatr Oncol · November 2016 OBJECTIVES: To characterize factors contributing to physical resilience in older cancer survivors, as demonstrated by resistance to decline or recovery (resilience). MATERIALS AND METHODS: We conducted a secondary analysis of data from a randomized control ... Full text Link to item Cite

Effect of Clinical and Attitudinal Characteristics on Obtaining Comprehensive Medication Reviews.

Journal Article J Manag Care Spec Pharm · April 2016 BACKGROUND: Comprehensive medication reviews (CMRs) consist of in-depth reviews of patients' medications to identify effectiveness or safety problems and often generate cost savings for individuals. Despite their advantages, CMRs are not widely obtained. P ... Full text Link to item Cite

The Effect of Receiving Treatment Within a Clinical Trial Setting on Survival and Quality of Care Perception in Advanced Stage Non-Small Cell Lung Cancer.

Journal Article Am J Clin Oncol · April 2016 OBJECTIVES: Treatment outcomes of advanced stage (IIIB and IV) non-small cell lung cancer (NSCLC) are poor. In this study, we explore the survival outcomes and the perception of the quality of care delivered in stage IIIB and IV NSCLC patients treated with ... Full text Link to item Cite

Predictors of Long-Term Quality of Life for Survivors of Stage II/III Rectal Cancer in the Cancer Care Outcomes Research and Surveillance Consortium.

Journal Article J Oncol Pract · July 2015 PURPOSE: Many patients do not receive guideline-recommended neoadjuvant chemoradiotherapy for resectable rectal cancer. Little is known regarding long-term quality of life (QOL) associated with various treatment approaches. Our objective was to determine p ... Full text Link to item Cite

Stimulating comprehensive medication reviews among Medicare Part D beneficiaries.

Journal Article Am J Manag Care · June 1, 2015 OBJECTIVES: To assess the impact of a patient engagement intervention utilizing the Medication User Self-Evaluation (MUSE) tool on the completion percentage of comprehensive medication reviews (CMRs) among Medicare Part D beneficiaries. STUDY DESIGN: A cas ... Link to item Cite

Survivorship care planning and its influence on long-term patient-reported outcomes among colorectal and lung cancer survivors: the CanCORS disease-free survivor follow-up study.

Journal Article J Cancer Surviv · June 2015 PURPOSE: This study aims to evaluate the relationship between survivorship care planning (SCP) and survivorship care and health outcomes reported by long-term lung and colorectal cancer survivors. METHODS: Participants (nā€‰=ā€‰832) were diagnosed and enrolled ... Full text Link to item Cite

The high frequency of healthcare use in patients one year prior to a sarcoidosis diagnosis.

Journal Article Sarcoidosis Vasc Diffuse Lung Dis · October 20, 2014 BACKGROUND: The clinical presentation of sarcoidosis can be varied. Prior investigations have shown that diagnosis is often delayed over six months, particularly in patients with pulmonary symptoms. Delays may lead to high healthcare use prior to diagnosis ... Link to item Cite

Field methods in medical record abstraction: assessing the properties of comparative effectiveness estimates.

Journal Article BMC Health Serv Res · September 15, 2014 BACKGROUND: Comparative effectiveness studies using Medicare claims data are vulnerable to treatment selection biases and supplemental data from a sample of patients has been recommended for examining the magnitude of this bias. Previous research using nat ... Full text Link to item Cite

Factors associated with use of preoperative chemoradiation therapy for rectal cancer in the Cancer Care Outcomes Research and Surveillance Consortium.

Journal Article Am J Clin Oncol · December 2013 PURPOSE: Preoperative (preop) chemoradiation therapy (CRT) improves local control and reduces toxicity more than postoperative (postop) CRT for the treatment of stages II/III rectal cancer, but studies suggest that many patients still receive postop CRT. W ... Full text Link to item Cite

Risks and benefits of bladder antimuscarinics among elderly residents of Veterans Affairs Community Living Centers.

Journal Article J Am Med Dir Assoc · October 2013 OBJECTIVES: To evaluate risks and benefits of bladder antimuscarinics (BAMs) among elderly long term care nursing home residents. DESIGN: Retrospective cohort study using a new user design and propensity score matching. SETTING: Veterans Affairs (VA) Commu ... Full text Link to item Cite

Development and initial assessment of the medication user self-evaluation (MUSE) tool.

Journal Article Clin Ther · March 2013 BACKGROUND: Using patient-reported data to supplement claims-based indicators may be helpful in identifying Medicare beneficiaries likely to benefit from medication therapy management (MTM) services. OBJECTIVE: Our objective was to develop and initially as ... Full text Link to item Cite

Representativeness of participants in the cancer care outcomes research and surveillance consortium relative to the surveillance, epidemiology, and end results program.

Journal Article Med Care · February 2013 BACKGROUND: The research goals of the Cancer Care Outcomes Research and Surveillance (CanCORS) Consortium are to determine how characteristics and beliefs of patients, providers, and health care organizations influence the treatments and outcomes of indivi ... Full text Link to item Cite

Factors affecting Medicare Part D beneficiaries' decision to receive comprehensive medication reviews.

Journal Article J Am Pharm Assoc (2003) · 2013 OBJECTIVES: To identify factors influencing Medicare Part D beneficiaries' decision to receive pharmacist-provided comprehensive medication reviews (CMRs) and to evaluate their experiences with pharmacist-provided CMRs. DESIGN: Cross-sectional descriptive ... Full text Link to item Cite

A comparison of health care use for physician-referred and self-referred episodes of outpatient physical therapy.

Journal Article Health Serv Res · April 2012 OBJECTIVE: To compare patient profiles and health care use for physician-referred and self-referred episodes of outpatient physical therapy (PT). DATA SOURCE: Five years (2003-2007) of private health insurance claims data, from a Midwest insurer, on benefi ... Full text Link to item Cite

Incidence of and risk factors for community-associated Clostridium difficile infection: a nested case-control study.

Journal Article BMC Infect Dis · July 15, 2011 BACKGROUND: Clostridium difficile is the most common cause of nosocomial infectious diarrhea in the United States. However, recent reports have documented that C. difficile infections (CDIs) are occurring among patients without traditional risk factors. Th ... Full text Link to item Cite

Adverse events among the elderly receiving chemotherapy for advanced non-small-cell lung cancer.

Journal Article J Clin Oncol · February 1, 2010 PURPOSE: To describe chemotherapy use and adverse events (AEs) for advanced-stage, non-small-cell lung cancer (NSCLC) in community practice, including descriptions according to variation by age. METHODS: We interviewed patients with newly diagnosed, stages ... Full text Link to item Cite

Effectiveness of a barcode medication administration system in reducing preventable adverse drug events in a neonatal intensive care unit: a prospective cohort study.

Journal Article J Pediatr · March 2009 OBJECTIVE: Patients are at risk of harm from medication errors. Barcode medication administration (BCMA) systems are recommended to mitigate preventable adverse drug events (ADEs). Our hypothesis was that a BCMA system would reduce preventable ADEs by 45% ... Full text Link to item Cite

Physician access and early nephrology care in elderly patients with end-stage renal disease.

Journal Article Kidney Int · December 2008 Early nephrology care may improve treatment outcomes of patients with end-stage renal disease. We sought to examine if physician access affects early nephrology care defined as visiting a nephrologist 12 to 4 months before initiating dialysis. The study po ... Full text Link to item Cite

Impact of travel distance on WISEWOMAN Intervention attendance for a rural population.

Journal Article Prev Med · November 2008 OBJECTIVE: The Well-Integrated Screening and Evaluation for Women Across the Nation (WISEWOMAN) is a program designed for financially disadvantaged women ages 40-64 and funded by the Centers for Disease Control and Prevention (CDC). This study investigates ... Full text Link to item Cite

Increasing the power: A practical approach to goodness-of-fit test for logistic regression models with continuous predictors

Journal Article Computational Statistics and Data Analysis · January 20, 2008 When continuous predictors are present, classical Pearson and deviance goodness-of-fit tests to assess logistic model fit break down. The Hosmer-Lemeshow test can be used in these situations. While simple to perform and widely used, it does not have desira ... Full text Cite

Perceived barriers to community-based health promotion program participation.

Journal Article Am J Health Behav · 2008 OBJECTIVES: To examine barriers and self-efficacy relative to attendance at a cardiovascular risk reduction program. METHODS: Subjects (N=161) represented 3 levels of program participation: full, minimum, and none. Survey scales for barriers to attendance ... Full text Link to item Cite

Effect of dialysis center profit-status on patient survival: a comparison of risk-adjustment and instrumental variable approaches.

Journal Article Health Serv Res · December 2006 OBJECTIVE: To compare the estimated effects of dialysis center profit status on patient survival using alternative estimation strategies with retrospective data. DATA SOURCES/STUDY SETTING: Patient and provider-level retrospective data from the United Stat ... Full text Link to item Cite

Mixed Models: Modelling Covariance Structure in the Analysis of Repeated Measures Data

Chapter · August 30, 2005 This chapter contains sections titled: Introduction Example Data Set Linear Mixed Model for Repeated Measures Covariance Structures for Repeated Measures Using the Mixed Procedure to Fit Linear Mixed Models Comparison of Fits of Covariance Structures Effec ... Full text Cite

Implementation of strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in U.S. hospitals.

Journal Article Infect Control Hosp Epidemiol · January 2005 OBJECTIVE: To examine the extent to which the strategies recommended by the National Foundation for Infectious Diseases (NFID)-Centers for Disease Control and Prevention (CDC) co-sponsored workshop, Antimicrobial Resistance in Hospitals: Strategies to Impr ... Full text Link to item Cite

Physician process and patient outcome measures for diabetes care: relationships to organizational characteristics.

Journal Article Med Care · September 2004 BACKGROUND: Optimal diabetes management relies on providers adhering to evidence-based practice guidelines in the processes of care delivery and patients adhering to self-management recommendations to maximize patient outcomes. PURPOSE: To explore: (1) the ... Full text Link to item Cite

The effect of physician characteristics and their practice environment on surgical referral patterns for early-stage breast cancer in Iowa.

Journal Article Am J Med Qual · 2004 The objective of this article was to examine whether characteristics of referring physicians and their practice environment were associated with surgical referral behavior for early-stage breast cancer patients. A total of 2801 women diagnosed with early-s ... Full text Link to item Cite

A randomized trial of behavioral management for continence with older rural women.

Journal Article Res Nurs Health · February 2002 Urinary incontinence (UI) is a commonly underreported and underdiagnosed condition. The purpose of this trial was to implement and evaluate behavioral management for continence (BMC), an intervention to manage symptoms of UI with older rural women in their ... Full text Link to item Cite

A Perceived Value Model for Explaining Patients' Intentions to Continue Use of Pharmaceutical Care Services

Journal Article Journal of Pharmaceutical Marketing and Management · January 1, 2001 The purpose of this study was to evaluate a perceived value model for explaining patients' willingness to continue use of pharmaceutical care services. A written questionnaire was administered to 154 patients in the waiting room of a pharmacist-run anticoa ... Full text Cite

Modelling covariance structure in the analysis of repeated measures data.

Journal Article Stat Med · July 15, 2000 The term 'repeated measures' refers to data with multiple observations on the same sampling unit. In most cases, the multiple observations are taken over time, but they could be over space. It is usually plausible to assume that observations on the same un ... Full text Link to item Cite

The effects of selective response preparation on corticospinal excitability.

Journal Article Cortex · February 2000 OBJECTIVE: Both motor imagery and selective motor cues enhance performance. Motor cortex is activated during motor imagery. We wanted to learn if selective motor cueing also activates motor cortex. METHODS: We gave normal right-handed subjects information ... Full text Link to item Cite

Patients' perceptions of the benefits of pharmaceutical care.

Journal Article J Am Pharm Assoc (Wash) · 2000 OBJECTIVE: To investigate patients' perceptions of the benefits of regular participation in pharmaceutical care services. DESIGN: Written survey of a convenience sample. SETTING: Pharmacist-run anticoagulation clinic in a Veterans Administration Medical Ce ... Full text Link to item Cite

A rodent model of spontaneous stereotypy: initial characterization of developmental, environmental, and neurobiological factors.

Journal Article Physiol Behav · April 1999 Stereotypies are patterns of motor behavior that are repetitive, excessive, topographically invariant, and that lack any obvious function or purpose. In humans, stereotyped behaviors are associated with psychiatric, neurological, and developmental disorder ... Full text Link to item Cite

Dietary caffeine, fluid intake and urinary incontinence in older rural women.

Journal Article Int Urogynecol J Pelvic Floor Dysfunct · 1999 Forty-one women completed the first phase (self-monitoring) of the Behavioral Management for Continence (BMC) intervention, while working with a nurse during home visits to reduce involuntary urine loss as part of the parent study involving older, rural wo ... Full text Link to item Cite

Issues related to using a short-form of the Center for Epidemiological Studies-Depression Scale.

Journal Article Psychol Rep · October 1998 The study examined the reliability and validity, including the factor structure, of a 10-item abbreviated version of the Center for Epidemiological Studies-Depression (CES-Depression) scale when administered as part of a mail questionnaire. It also examine ... Full text Link to item Cite

Children's health care use in the Healthy Kids Program.

Journal Article Pediatrics · December 1997 BACKGROUND: In 1990, the Florida Legislature established the Florida Healthy Kids Corporation to implement the concept of school enrollment-based health insurance coverage for children. The county school districts are used as a grouping mechanism to negoti ... Full text Link to item Cite

The School Enrollment-Based Health Insurance program: socioeconomic factors in enrollees' use of health services.

Journal Article Am J Public Health · December 1996 OBJECTIVES: The School Enrollment-Based Health Insurance program is designed to reduce financial barriers to children's health care use. This study sought to determine if any socioeconomic measures differed between enrollees with at least one health care e ... Full text Link to item Cite

A survey off methods for analyzing clustered binary response data

Journal Article International Statistical Review · January 1, 1996 A comprehensive survey of regression-type models for clusters of correlated binary outcomes, including longitudinal data, is presented. In particular, we focus on models which can accommodate both between- and within-cluster categorical and continuous cova ... Full text Cite

Role orientation and community pharmacists' participation in a project to improve patient care.

Journal Article Soc Sci Med · February 1995 Community pharmacists are being assigned increased responsibility in assuring the appropriateness and effectiveness of drug therapy. This increased responsibility is reflected in recently passed legislation (OBRA '90) in the United States that requires pha ... Full text Link to item Cite

Community pharmacists' documentation of intervention on drug related problems of elderly patients

Journal Article Journal of Social and Administrative Pharmacy · December 1, 1994 Few empirical investigations have documented pharmacists interventions with physicians and patients. This research describes community pharmacists' documentation of efforts to assess drug use of elderly patients who were on chronic drug therapies and to co ... Cite

Potential drug interactions in a high risk ambulatory elderly population

Journal Article Journal of Geriatric Drug Therapy · July 4, 1994 Objective. This study was designed to determine the rates of occurrence of potential drug-drug interactions in ambulatory patients aged 60 years or older who were taking medications to treat chronic conditions. Variables which differentiated patients with ... Full text Cite

Effects of an education program for community pharmacists on detecting drug-related problems in elderly patients.

Journal Article Med Care · May 1993 Community pharmacists are in a position to assume increased responsibility for preventing and resolving drug-related problems in ambulatory patients. Such an expanded role is mandated under provisions of the Omnibus Budget Reconciliation Act of 1990. The n ... Full text Link to item Cite

Evaluation of peritoneal fluid following intestinal resection and anastomosis in horses.

Journal Article Am J Vet Res · February 1992 Postoperative abdominal fluid changes were compared in 2 groups of horses; those undergoing double small-colon resection and anastomosis (n = 10) and those undergoing exploratory celiotomy alone (n = 5). Peritoneal fluid was collected before surgery and on ... Link to item Cite

Comparison of staple and suture techniques for end-to-end anastomosis of the small colon in horses.

Journal Article Am J Vet Res · September 1988 Two techniques for end-to-end anastomosis of the small colon were evaluated in each of 6 horses. A simple interrupted suture pattern that excluded the mucosa and was oversewn with an inverting suture was compared with a triangulated double-row pattern of s ... Link to item Cite

A multistage model of hospital bed requirements.

Journal Article Health Serv Res · August 1988 This article presents a model for projecting future hospital bed requirements, based on clinical judgment and basic probability theory. Clinical judgment is used to define various categories of care, including a category for patients who are inappropriatel ... Link to item Cite

Nursing administration research in hospitals and schools of nursing.

Journal Article J Nurs Adm · February 1988 "Nursing service administration is in the most desperate need of research..." So said Herman Finer, well-known professor at the University of Chicago and in 1952, director of the Kellogg Nursing Service Administration Research Project. Today, 35 years late ... Link to item Cite

Tetracyclines as Fluorescent Bone Markers in Cotton and Roof Rats

Conference ASTM Special Technical Publication · January 1, 1988 Three tetracycline compounds, demeclocycline hydrochloride (DMCH), tetracycline hydrochloride (TCH), and chlortetracycline hydrochloride (CTH), were administered by gavage and tested as fluorescent bone markers for adult cotton (Sigmodon hispidus) and roof ... Full text Cite

Delineation of nursing administration research priorities.

Journal Article Nurs Res · 1987 The purposes of this national study were to determine: (a) a definition of nursing administration research and (b) priority nursing administration research questions. Brainstorming was used initially with Council on Graduate Education for Administration in ... Link to item Cite

Comparing mean ranks for repeated measures data

Journal Article Communications in Statistics - Theory and Methods · January 1, 1986 Rank tests are considered that compare t treatments in repeated measures designs. A statistic is given that contains as special cases several that have been proposed for this problem, including one that corresponds to the randomized block ANOVA statistic a ... Full text Cite

Human thrombocytopenia is associated with structural abnormalities of the endothelium that are ameliorated by glucocorticosteroid administration.

Journal Article Blood · January 1986 Capillary fragility is characteristic of severe thrombocytopenia. This mechanical weakness may not be solely accounted for by decreased ability of platelets to repair endothelial breaks. Platelets may have a role in maintaining endothelial hemostasis. This ... Link to item Cite

Robust estimation in growth curve models

Journal Article Communications in Statistics - Theory and Methods · January 1, 1985 The growth curve model introduced by Potthoff and Roy (1964) is a general statistical model which includes as special cases regression models and both univariate and multivariate analysis of variance models. The methods currently available for estimating t ... Full text Cite

Uterine blood flow: periodic fluctuations of its rate during pregnancy.

Journal Article Am J Physiol · December 1983 Daily measurements of the rate of uterine blood flow (ml/min) during the last half of pregnancy of four normal sheep reflected a 17-day cyclic fluctuation (range, 9.5-42 days) superimposed on a linear increase over time. The cyclic increase was not detecte ... Full text Link to item Cite

Uterine blood flow: Periodic fluctuations of its rate during pregnancy

Journal Article American Journal of Physiology - Regulatory Integrative and Comparative Physiology · December 1, 1983 Daily measurements of the rate of uterine blood flow (ml/min) during the last half of pregnancy of four normal sheep reflected a 17-day cyclic fluctuation (range, 9.5-42 days) superimposed on a linear increase over time. The cyclic increase was not detecte ... Cite

Accuracy of two systems for blood glucose monitoring without a meter (Chemstrip/Visidex).

Journal Article Diabetes Care · 1983 Blood specimens collected from 159 campers were tested using Visidex (VD) (Ames Company, Elkhart, Indiana) and Chemstrip (CS) (Bio-Dynamics, Boehringer Mannheim, Indianapolis, Indiana) compared with glucose analyzer (GA) results. Readers were physicians, t ... Full text Link to item Cite

COMPARABILITY OF CANCER PATIENTS AND HOSPITALS FROM THE IOWA TUMOR REGISTRY.

Conference Proceedings of the Hawaii International Conference on System Science · December 1, 1981 Cite