Journal ArticleCell Rep · August 27, 2024
Vocal communication depends on distinguishing self-generated vocalizations from other sounds. Vocal motor corollary discharge (CD) signals are thought to support this ability by adaptively suppressing auditory cortical responses to auditory feedback. One c ...
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Journal ArticleJ Exp Psychol Gen · August 2024
Counterfactual theories propose that people's capacity for causal judgment depends on their ability to consider alternative possibilities: The lightning strike caused the forest fire because had it not struck, the forest fire would not have ensued. To acco ...
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Journal ArticleeNeuro · July 2023
The brain interprets sensory inputs to guide behavior, but behavior itself disrupts sensory inputs. Perceiving a coherent world while acting in it constitutes active perception. For example, saccadic eye movements displace visual images on the retina and y ...
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Journal ArticlePLoS Comput Biol · May 2023
Learning skilled behaviors requires intensive practice over days, months, or years. Behavioral hallmarks of practice include exploratory variation and long-term improvements, both of which can be impacted by circadian processes. During weeks of vocal pract ...
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Journal ArticleSoc Cogn Affect Neurosci · February 23, 2023
Jury decisions are among the most consequential social decisions in which bias plays a notable role. While courts take measures to reduce the influence of non-evidentiary factors, jurors may still incorporate biases into their decisions. One common bias, c ...
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Journal ArticleAdvances in neural information processing systems · December 2022
Among the most striking features of retinal organization is the grouping of its output neurons, the retinal ganglion cells (RGCs), into a diversity of functional types. Each of these types exhibits a mosaic-like organization of receptive fields (RFs) that ...
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Journal ArticleJ Neurosci · October 5, 2022
Efforts to explain complex human decisions have focused on competing theories emphasizing utility and narrative mechanisms. These are difficult to distinguish using behavior alone. Both narrative and utility theories have been proposed to explain juror dec ...
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Journal ArticleCognition · June 2022
When comparing the roles of the lightning strike and the dry climate in causing the forest fire, one might think that the lightning strike is more of a cause than the dry climate, or one might think that the lightning strike completely caused the fire whil ...
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ConferenceProceedings of the 44th Annual Meeting of the Cognitive Science Society: Cognitive Diversity, CogSci 2022 · January 1, 2022
The human capacity for causal judgment has long been thought to depend on an ability to consider counterfactual alternatives: the lightning strike caused the forest fire because had it not struck, the forest fire would not have ensued. To accommodate psych ...
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ConferenceAdv Neural Inf Process Syst · December 2021
While most classic studies of function in experimental neuroscience have focused on the coding properties of individual neurons, recent developments in recording technologies have resulted in an increasing emphasis on the dynamics of neural populations. Th ...
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Journal ArticleNature · November 2021
Musical and athletic skills are learned and maintained through intensive practice to enable precise and reliable performance for an audience. Consequently, understanding such complex behaviours requires insight into how the brain functions during both prac ...
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Journal ArticleProc Natl Acad Sci U S A · September 28, 2021
Many sensory systems utilize parallel ON and OFF pathways that signal stimulus increments and decrements, respectively. These pathways consist of ensembles or grids of ON and OFF detectors spanning sensory space. Yet, encoding by opponent pathways raises a ...
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Journal Article · August 31, 2021
While most classic studies of function in experimental neuroscience have
focused on the coding properties of individual neurons, recent developments in
recording technologies have resulted in an increasing emphasis on the dynamics
of neural populations. Th ...
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Dataset · May 24, 2021
Increases in the scale and complexity of behavioral data pose an increasing challenge for data analysis. A common strategy involves replacing entire behaviors with small numbers of handpicked, domain-specific features, but this approach suffers from severa ...
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Journal ArticleElife · May 14, 2021
Increases in the scale and complexity of behavioral data pose an increasing challenge for data analysis. A common strategy involves replacing entire behaviors with small numbers of handpicked, domain-specific features, but this approach suffers from severa ...
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Journal ArticleNature · April 2021
The output of the retina is organized into many detector grids, called 'mosaics', that signal different features of visual scenes to the brain1-4. Each mosaic comprises a single type of retinal ganglion cell (RGC), whose receptive fields tile visual space. ...
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Journal ArticlePhilos Trans R Soc Lond B Biol Sci · March 2021
Humans and other animals evolved to make decisions that extend over time with continuous and ever-changing options. Nonetheless, the academic study of decision-making is mostly limited to the simple case of choice between two options. Here, we advocate tha ...
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Journal ArticlePhilos Trans R Soc Lond B Biol Sci · March 2021
Information about social partners is innately valuable to primates. Decisions about which sources of information to consume are highly naturalistic but also complex and place unusually strong demands on the brain's decision network. In particular, both the ...
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Journal ArticleNeuropsychopharmacology · February 2021
The ability to maximize rewards and minimize the costs of obtaining them is vital to making advantageous explore/exploit decisions. Exploratory decisions are theorized to be greater among individuals with attention-deficit/hyperactivity disorder (ADHD), po ...
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Journal ArticleJ Neurovirol · February 2021
Diagnosis of HIV-associated neurocognitive impairment (NCI) continues to be a clinical challenge. The purpose of this study was to develop a prediction model for NCI among people with HIV using clinical- and magnetic resonance imaging (MRI)-derived feature ...
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Journal ArticleJournal of Statistical Software · January 1, 2021
Random variables and their distributions are a central part in many areas of statistical methods. The Distributions.jl package provides Julia users and developers tools for work-ing with probability distributions, leveraging Julia features for their intuit ...
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Journal Article · 2021
Current neuroscience research is often limited to testing predetermined hypotheses and post hoc analysis of already collected data. Adaptive experimental designs, in which modeling drives ongoing data collection and selects experimental manipulations, offe ...
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Journal Article · 2021
Many sensory systems utilize parallel ON and OFF pathways that signal stimulus increments and decrements, respectively. These pathways consist of ensembles or grids of ON and OFF detectors spanning sensory space. Yet encoding by opponent pathways raises a ...
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Journal Article · 2021
While functional magnetic resonance imaging (fMRI) remains one of the most widespread and important methods in basic and clinical neuroscience, the data it produces—time series of brain volumes—continue to pose daunting analysis challenges. The current sta ...
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Journal Article · 2021
Identified ligands for > 500 mouse ORs ORs are specifically tuned towards individual odorants and their molecular properties Odor molecular properties are informative of odor responses Predictive modeling and convergent evolution analyses suggest specific ...
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ConferenceProceedings of Machine Learning Research · January 1, 2021
While functional magnetic resonance imaging (fMRI) remains one of the most widespread and important methods in basic and clinical neuroscience, the data it produces—time series of brain volumes—continue to pose daunting analysis challenges. The current sta ...
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Journal ArticleElife · December 29, 2020
Animals vocalize only in certain behavioral contexts, but the circuits and synapses through which forebrain neurons trigger or suppress vocalization remain unknown. Here, we used transsynaptic tracing to identify two populations of inhibitory neurons that ...
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Journal ArticleJ Neurophysiol · September 1, 2020
The environment is sampled by multiple senses, which are woven together to produce a unified perceptual state. However, optimally unifying such signals requires assigning particular signals to the same or different underlying objects or events. Many prior ...
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Journal Article · July 27, 2020
One of the primary goals of systems neuroscience is to relate the structure
of neural circuits to their function, yet patterns of connectivity are
difficult to establish when recording from large populations in behaving
organisms. Many previous approaches ...
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Journal ArticleSoc Cogn Affect Neurosci · June 23, 2020
Understanding how humans make competitive decisions in complex environments is a key goal of decision neuroscience. Typical experimental paradigms constrain behavioral complexity (e.g. choices in discrete-play games), and thus, the underlying neural mechan ...
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ConferenceAdvances in Neural Information Processing Systems · January 1, 2020
One of the primary goals of systems neuroscience is to relate the structure of neural circuits to their function, yet patterns of connectivity are difficult to establish when recording from large populations in behaving organisms. Many previous approaches ...
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Journal ArticleCurrent Opinion in Behavioral Sciences · October 1, 2019
Questions of social behavior are simultaneously among the most fundamental in neuroscience and the most challenging in artificial intelligence. Yet despite decades of work, a unified perspective from the cognitive and computational approaches to the proble ...
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Journal ArticleNat Commun · April 18, 2019
Previous studies of strategic social interaction in game theory have predominantly used games with clearly-defined turns and limited choices. Yet, most real-world social behaviors involve dynamic, coevolving decisions by interacting agents, which poses cha ...
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Journal ArticlePLoS Comput Biol · March 2019
Understanding the principles by which agents interact with both complex environments and each other is a key goal of decision neuroscience. However, most previous studies have used experimental paradigms in which choices are discrete (and few), play is sta ...
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Journal Article · 2019
The environment is sampled by multiple senses, which are woven together to produce a unified perceptual state. However, optimally unifying such signals requires assigning particular signals to the same or different underlying objects or events. Many prior ...
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Journal Article · 2019
SUMMARY Increases in the scale and complexity of behavioral data pose an increasing challenge for data analysis. A common strategy involves replacing entire behaviors with small numbers of handpicked, domain-specific features, but this approach su ...
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Journal ArticleNat Hum Behav · November 2018
Concerns over wrongful convictions have spurred an increased focus on understanding criminal justice decision-making. This study describes an experimental approach that complements conventional mock-juror experiments and case studies by providing a rapid, ...
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Journal ArticleJ Neurosci · September 26, 2018
The striatum supports learning from immediate feedback by coding prediction errors (PEs), whereas the hippocampus (HC) plays a parallel role in learning from delayed feedback. Both regions show evidence of decline in human aging, but behavioral research su ...
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Journal Article · August 5, 2018
AbstractPrevious approaches to investigating strategic social interaction in game theory have predominantly used games with clearly-defined turns and limited choices. However, most real-world social behaviors involve dynami ...
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Journal ArticleNeuropsychopharmacology · September 2017
Foraging is a fundamental behavior, and many types of animals appear to have solved foraging problems using a shared set of mechanisms. Perhaps the most common foraging problem is the choice between exploiting a familiar option for a known reward and explo ...
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Journal ArticlePsychon Bull Rev · August 2017
What we are currently thinking influences where we attend. The finding that active maintenance of visual items in working memory (WM) biases attention toward memory-matching objects-even when WM content is irrelevant for attentional goals-suggests a tight ...
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Journal ArticlePLoS Comput Biol · August 2017
Experiments that study neural encoding of stimuli at the level of individual neurons typically choose a small set of features present in the world-contrast and luminance for vision, pitch and intensity for sound-and assemble a stimulus set that systematica ...
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Journal Article · February 23, 2017
Despite increasing attention paid to the need for fast, scalable methods to
analyze next-generation neuroscience data, comparatively little attention has
been paid to the development of similar methods for behavioral analysis. Just
as the volume and comple ...
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Journal ArticleFront Neurosci · 2017
The ability to adaptively minimize not only motor but cognitive symptoms of neurological diseases, such as Parkinson's Disease (PD) and obsessive-compulsive disorder (OCD), is a primary goal of next-generation deep brain stimulation (DBS) devices. On the b ...
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Journal ArticleSoc Cogn Affect Neurosci · June 2016
Human altruism is often expressed through charitable donation-supporting a cause that benefits others in society, at cost to oneself. The underlying mechanisms of this other-regarding behavior remain imperfectly understood. By recording event-related-poten ...
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Journal ArticleProc Natl Acad Sci U S A · December 29, 2015
Social decisions require evaluation of costs and benefits to oneself and others. Long associated with emotion and vigilance, the amygdala has recently been implicated in both decision-making and social behavior. The amygdala signals reward and punishment, ...
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Journal ArticleBehav Neurosci · October 2015
Why do people gamble? Conventional views hold that gambling may be motivated by irrational beliefs, risk-seeking, impulsive temperament, or dysfunction within the same reward circuitry affected by drugs of abuse. An alternate, unexplored perspective is tha ...
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Journal ArticleVisual Cognition · August 9, 2015
Sophisticated machine learning algorithms have been successfully applied to functional neuroimaging data in order to characterize internal cognitive states. But is it possible to “mind-read” without the scanner? Capitalizing on the robust finding that the ...
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Journal ArticlePsychiatry Res · December 30, 2014
The adaptive trade-off between exploration and exploitation is a key component in models of reinforcement learning. Over the past decade, these models have been applied to the study of reward-seeking behavior. Drugs of addiction induce reward-seeking behav ...
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Journal ArticleNeuron · June 4, 2014
Neuroeconomics applies models from economics and psychology to inform neurobiological studies of choice. This approach has revealed neural signatures of concepts like value, risk, and ambiguity, which are known to influence decision making. Such observatio ...
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Journal ArticleAnim Cogn · May 2014
We investigated the precision of the approximate number system (ANS) in three lemur species (Lemur catta, Eulemur mongoz, and Eulemur macaco flavifrons), one Old World monkey species (Macaca mulatta) and humans (Homo sapiens). In Experiment 1, four individ ...
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Journal ArticleFront Neurosci · 2014
Complex natural environments favor the dynamic alignment of neural processing between goal-relevant stimuli and conflicting but biologically salient stimuli like social competitors or predators. The biological mechanisms that regulate dynamic changes in vi ...
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Journal ArticlePLoS One · 2014
In social environments, decisions not only determine rewards for oneself but also for others. However, individual differences in pro-social behaviors have been typically studied through self-report. We developed a decision-making paradigm in which particip ...
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Journal ArticleProc Natl Acad Sci U S A · September 17, 2013
Intertemporal choice tasks, which pit smaller/sooner rewards against larger/later ones, are frequently used to study time preferences and, by extension, impulsivity and self-control. When used in animals, many trials are strung together in sequence and an ...
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Journal ArticleNeuron · September 4, 2013
Dopamine neurons are well known for signaling reward-prediction errors. In this issue, Matsumoto and Takada (2013) show that some dopamine neurons also signal salient events during progression through a visual search task requiring working memory and susta ...
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Journal ArticleJ Exp Biol · August 15, 2013
Conspicuous, multicomponent ornamentation in male animals can be favored by female mate choice but we know little about the cognitive processes females use to evaluate these traits. Sexual selection may favor attention mechanisms allowing the choosing fema ...
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Journal ArticleProc Natl Acad Sci U S A · June 18, 2013
A neuroethological approach to human and nonhuman primate behavior and cognition predicts biological specializations for social life. Evidence reviewed here indicates that ancestral mechanisms are often duplicated, repurposed, and differentially regulated ...
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Journal ArticleJ Neurosci · April 17, 2013
Success in many decision-making scenarios depends on the ability to maximize gains and minimize losses. Even if an agent knows which cues lead to gains and which lead to losses, that agent could still make choices yielding suboptimal rewards. Here, by anal ...
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Journal ArticleExp Clin Psychopharmacol · February 2013
Advantageous decision-making is an adaptive trade-off between exploring alternatives and exploiting the most rewarding option. This trade-off may be related to maladaptive decision-making associated with nicotine dependence; however, explore/exploit behavi ...
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Journal ArticleJ Exp Anal Behav · January 2013
Foundational studies in decision making focused on behavior as the most accessible and reliable data on which to build theories of choice. More recent work, however, has incorporated neural data to provide insights unavailable from behavior alone. Among ot ...
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Journal ArticleFront Neurosci · 2013
As studies of the neural circuits underlying choice expand to include more complicated behaviors, analysis of behaviors elicited in laboratory paradigms has grown increasingly difficult. Social behaviors present a particular challenge, since inter- and int ...
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Journal ArticleCurr Opin Neurobiol · December 2012
A neuroethological approach to decision-making considers the effect of evolutionary pressures on neural circuits mediating choice. In this view, decision systems are expected to enhance fitness with respect to the local environment, and particularly effici ...
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Journal ArticleNat Neurosci · February 24, 2012
How do we make decisions? A study uses MEG to provide the spatial as well as the temporal resolution needed to answer this question, together with computational modeling, which allows for complex non-linear decision models. This work helps resolve some of ...
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Journal ArticleNat Neurosci · June 5, 2011
Deciding when to leave a depleting resource to exploit another is a fundamental problem for all decision makers. The neuronal mechanisms mediating patch-leaving decisions remain unknown. We found that neurons in primate (Macaca mulatta) dorsal anterior cin ...
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Journal ArticleTrends Cogn Sci · April 2011
When has the world changed enough to warrant a new approach? The answer depends on current needs, behavioral flexibility and prior knowledge about the environment. Formal approaches solve the problem by integrating the recent history of rewards, errors, un ...
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Journal ArticleJ Neurosci · March 16, 2011
In attentional models of learning, associations between actions and subsequent rewards are stronger when outcomes are surprising, regardless of their valence. Despite the behavioral evidence that surprising outcomes drive learning, neural correlates of uns ...
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Journal ArticleFrontiers in behavioral neuroscience · January 2010
In most natural decision contexts, the process of selecting among competing actions takes place in the presence of informative, but potentially ambiguous, stimuli. Decisions about magnitudes - quantities like time, length, and brightness that are linearly ...
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Journal ArticleFront Psychol · 2010
Animals are notoriously impulsive in common laboratory experiments, preferring smaller, sooner rewards to larger, delayed rewards even when this reduces average reward rates. By contrast, the same animals often engage in natural behaviors that require extr ...
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Journal ArticleCurr Biol · September 29, 2009
In dynamic environments, adaptive behavior requires striking a balance between harvesting currently available rewards (exploitation) and gathering information about alternative options (exploration). Such strategic decisions should incorporate not only rec ...
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Journal ArticleNeuron · September 24, 2009
Single neurons in several brain areas intervening between sensation and action signal the accumulation of sensory evidence favoring a particular behavioral response. Two new studies show that these same neurons encode decision confidence and that decision ...
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Journal ArticleScience · May 15, 2009
The neural mechanisms supporting the ability to recognize and respond to fictive outcomes, outcomes of actions that one has not taken, remain obscure. We hypothesized that neurons in the anterior cingulate cortex (ACC), which monitors the consequences of a ...
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Journal ArticlePhilos Trans R Soc Lond B Biol Sci · December 12, 2008
Ethology, the evolutionary science of behaviour, assumes that natural selection shapes behaviour and its neural substrates in humans and other animals. In this view, the nervous system of any animal comprises a suite of morphological and behavioural adapta ...
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Journal ArticleJournal of High Energy Physics · May 1, 2003
Employing the string bit formalism of [18], we identify the basis transformation that relates BMN operators in N = 4 gauge theory to string states in the dual string field theory at finite g2 = J2/N. In this basis, the supercharge truncates at linear order ...
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Journal ArticleJournal of High Energy Physics · June 1, 2002
We consider the dynamics of p anti-D3 branes inside the Klebanov-Strassler geometry, the deformed conifold with M units of RR 3-form flux around the S 3. We find that for p ≪ M the system relaxes to a nonsupersymmetric NS 5-brane "giant graviton" configura ...
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Journal ArticlePhysical Review Letters · January 1, 1999
The oscillation frequencies of collective excitations of a trapped Bose-Einstein condensate, when calculated in the mean-field approximation and in the Thomas-Fermi limit, are independent of the scattering length a. We calculate the leading corrections to ...
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