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Marilyn J Hockenberry

Bessie Baker Distinguished Professor Emerita of the School of Nursing
School of Nursing
Box 2712, Hock Center Suite 405, Durham, NC 27710
Hock Center, Room 3057, Durham, NC 27710

Selected Publications


Symptoms, Physical Activity, and Biomarkers in Children at the End of Leukemia Maintenance Therapy.

Journal Article Journal of pediatric hematology/oncology nursing · November 2023 Background: Symptoms in children with acute lymphocytic leukemia (ALL) change over the trajectory of treatment but little is known about their symptoms as treatment ends. Physical activity may help decrease symptom distress and is vital for ongoing ... Full text Cite

Assessment of proxy-reported responses as predictors of motor and sensory peripheral neuropathy in children with B-lymphoblastic leukemia.

Journal Article Pediatric blood & cancer · November 2023 Chemotherapy-induced peripheral neuropathy (CIPN), a common condition in children with acute lymphoblastic leukemia, can be challenging to diagnose. Using data from Children's Oncology Group AALL0932 physical function study, we sought to determine if paren ... Full text Cite

Addressing the childhood cancer crisis in sub-Saharan Africa.

Journal Article The Lancet. Oncology · July 2023 Full text Cite

Longitudinal investigation of suicidal ideation and associated factors during pediatric acute lymphoblastic leukemia chemotherapy.

Journal Article Psycho-oncology · October 2022 ObjectiveThis study describes the prevalence of suicidal ideation (SI) during acute lymphoblastic leukemia (ALL) therapy and investigates the influence of clinical factors and physical symptoms on SI.MethodsThe Children's Depressive Inven ... Full text Cite

Persistence of Chemotherapy-Induced Peripheral Neuropathy Despite Vincristine Reduction in Childhood B-Acute Lymphoblastic Leukemia.

Journal Article Journal of the National Cancer Institute · August 2022 BackgroundChildren with B-acute lymphoblastic leukemia (B-ALL) are at risk for chemotherapy-induced peripheral neuropathy (CIPN). Children's Oncology Group AALL0932 randomized reduction in vincristine and dexamethasone (every 4 weeks vs 12 weeks d ... Full text Cite

Delphi Method to Develop a Palliative Care Tool for Children and Families in Sub-Saharan Africa.

Journal Article Journal of pain and symptom management · June 2022 ContextIn sub-Saharan Africa, there is no standardized approach to pediatric palliative care assessment. Because of this, there is a critical demand for evidence-based assessment tools that identify the specialized needs of children and their fami ... Full text Cite

Association between fatigue and sleep disturbances during treatment for pediatric acute lymphoblastic leukemia and posttreatment neurocognitive performance.

Journal Article Pediatric blood & cancer · May 2022 BackgroundSurvivors of pediatric acute lymphoblastic leukemia (ALL) are at increased risk of neurocognitive weakness in the areas of attention, executive function, and processing speed. Although fatigue and sleep disturbances are frequent complica ... Full text Cite

Symptom Clusters, Physical Activity, and Quality of Life: A Latent Class Analysis of Children During Maintenance Therapy for Leukemia.

Journal Article Cancer nursing · March 2022 BackgroundChildren undergoing treatment for acute lymphocytic leukemia (ALL) report co-occurring symptoms of fatigue, sleep disturbances, and depression as a symptom cluster. Physical activity (PA) may influence symptom severity and quality of lif ... Full text Cite

Pediatric Education Discharge Support Strategies for Newly Diagnosed Children With Cancer.

Journal Article Cancer nursing · November 2021 BackgroundDischarge education practices vary among institutions and lack a standardized approach for newly diagnosed pediatric oncology patients and their parents.ObjectiveThe purpose of this American Nurses Credentialing Center-supported ... Full text Cite

Biomarkers and Cognitive Function in Children and Adolescents During Maintenance Therapy for Leukemia.

Journal Article Oncology nursing forum · November 2021 ObjectivesTo explore the relationship between biomarkers of oxidative stress and inflmmation in cerebrospinal fluid (CSF) and cognitive function in children receiving maintenance therapy for acute lymphocytic leukemia (ALL).Sample & settin ... Full text Cite

Prospective patient-reported symptom profiles associated with pediatric acute lymphoblastic leukemia relapse.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · May 2021 PurposeDespite improvements in frontline pediatric acute lymphoblastic leukemia (ALL) treatment, relapse remains a concern. Research in adult cancer patients suggests that patient-reported symptoms may predict survival, but the relationship betwee ... Full text Cite

Cerebrospinal Fluid Metabolomic Profiles Associated With Fatigue During Treatment for Pediatric Acute Lymphoblastic Leukemia.

Journal Article Journal of pain and symptom management · March 2021 ContextCancer-related fatigue (CRF) is one of the most distressing and persistent symptoms reported during pediatric acute lymphoblastic leukemia (ALL) therapy; however, information on the pathways underlying CRF severity is limited.Objectives ... Full text Cite

Improving Peripheral Intravenous Catheter Care for Children with Cancer Receiving Chemotherapy in Malawi.

Journal Article Journal of pediatric nursing · January 2021 PurposeTo change pediatric oncology nursing management of peripheral intravenous catheter (PIVC) insertion and care based on current best evidence.Design and methodsPractice change strategies were developed, and nurses completed education ... Full text Cite

Promoting pediatric oncology nursing excellence in sub-Saharan Africa using project ECHO

Journal Article International Journal of Africa Nursing Sciences · January 1, 2021 Purpose: The designation of the year 2020 as the International Year of the Nurse provides time for reflection on the importance of nursing in meeting the needs of the under-served throughout the world. The purpose of this project was to implement an educat ... Full text Cite

Distance-Based Education for Nurses Caring for Children With Cancer in Sub-Saharan Africa.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2020 Nursing specialization in the care of children with cancer provides the foundation for implementing successful childhood cancer and blood disorder treatment programs throughout the world. Excellence in nursing education is at the center of all that is need ... Full text Cite

The Longitudinal Parallel Process Analysis of Biomarkers of Oxidative Stress, Symptom Clusters, and Cognitive Function in Children With Leukemia.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2020 Background: During treatment for acute lymphoblastic leukemia (ALL), children report co-occurring symptoms of fatigue, sleep disturbance, pain, nausea, and depression as a symptom cluster. Central nervous system-directed ALL therapies also put child ... Full text Cite

Implementing a pediatric oncology nursing multisite trial.

Journal Article Journal for specialists in pediatric nursing : JSPN · July 2020 Purpose/backgroundThe Parent Educational Discharge Support Strategies (PEDSS) nursing study includes 16 magnet pediatric oncology institutions across the United States and one in Saudi Arabia, evaluating a nurse-led parent educational discharge su ... Full text Cite

Promoting Direct Care Nurse Engagement in Research in Magnet Hospitals: The Parent Education Discharge Support Strategies Experience.

Journal Article The Journal of nursing administration · May 2020 Multisite study participation provides an opportunity for hospitals to gain access to the resources required to facilitate nursing research. The nurse-led Parent Educational Discharge Support Strategies for children newly diagnosed with cancer (PEDSS) mult ... Full text Cite

Influence of Inflammatory and Oxidative Stress Pathways on Longitudinal Symptom Experiences in Children With Leukemia.

Journal Article Biological research for nursing · October 2019 PurposeThe purpose of this study was to explore the influence of oxidative stress (F2-isoprostanes) and inflammatory (interleukin [IL]-8) biomarkers on symptom trajectories during the first 18 months of childhood leukemia treatment.Method ... Full text Cite

Impact of Childhood Leukemia Treatment on Attention Measured by the Continuous Performance Test Factor Structure.

Journal Article Oncology nursing forum · July 2019 ObjectivesTo describe the impact of central nervous system-directed treatment on attention and its relation to academic outcomes in childhood acute lymphoblastic leukemia (ALL) survivors.Sample & setting51 children diagnosed with ALL ... Full text Cite

Symptoms, Physical Activity, and Biomarkers in Children at the End of Leukemia Maintenance Therapy.

Journal Article Journal of pediatric hematology/oncology nursing · November 2023 Background: Symptoms in children with acute lymphocytic leukemia (ALL) change over the trajectory of treatment but little is known about their symptoms as treatment ends. Physical activity may help decrease symptom distress and is vital for ongoing ... Full text Cite

Assessment of proxy-reported responses as predictors of motor and sensory peripheral neuropathy in children with B-lymphoblastic leukemia.

Journal Article Pediatric blood & cancer · November 2023 Chemotherapy-induced peripheral neuropathy (CIPN), a common condition in children with acute lymphoblastic leukemia, can be challenging to diagnose. Using data from Children's Oncology Group AALL0932 physical function study, we sought to determine if paren ... Full text Cite

Addressing the childhood cancer crisis in sub-Saharan Africa.

Journal Article The Lancet. Oncology · July 2023 Full text Cite

Longitudinal investigation of suicidal ideation and associated factors during pediatric acute lymphoblastic leukemia chemotherapy.

Journal Article Psycho-oncology · October 2022 ObjectiveThis study describes the prevalence of suicidal ideation (SI) during acute lymphoblastic leukemia (ALL) therapy and investigates the influence of clinical factors and physical symptoms on SI.MethodsThe Children's Depressive Inven ... Full text Cite

Persistence of Chemotherapy-Induced Peripheral Neuropathy Despite Vincristine Reduction in Childhood B-Acute Lymphoblastic Leukemia.

Journal Article Journal of the National Cancer Institute · August 2022 BackgroundChildren with B-acute lymphoblastic leukemia (B-ALL) are at risk for chemotherapy-induced peripheral neuropathy (CIPN). Children's Oncology Group AALL0932 randomized reduction in vincristine and dexamethasone (every 4 weeks vs 12 weeks d ... Full text Cite

Delphi Method to Develop a Palliative Care Tool for Children and Families in Sub-Saharan Africa.

Journal Article Journal of pain and symptom management · June 2022 ContextIn sub-Saharan Africa, there is no standardized approach to pediatric palliative care assessment. Because of this, there is a critical demand for evidence-based assessment tools that identify the specialized needs of children and their fami ... Full text Cite

Association between fatigue and sleep disturbances during treatment for pediatric acute lymphoblastic leukemia and posttreatment neurocognitive performance.

Journal Article Pediatric blood & cancer · May 2022 BackgroundSurvivors of pediatric acute lymphoblastic leukemia (ALL) are at increased risk of neurocognitive weakness in the areas of attention, executive function, and processing speed. Although fatigue and sleep disturbances are frequent complica ... Full text Cite

Symptom Clusters, Physical Activity, and Quality of Life: A Latent Class Analysis of Children During Maintenance Therapy for Leukemia.

Journal Article Cancer nursing · March 2022 BackgroundChildren undergoing treatment for acute lymphocytic leukemia (ALL) report co-occurring symptoms of fatigue, sleep disturbances, and depression as a symptom cluster. Physical activity (PA) may influence symptom severity and quality of lif ... Full text Cite

Pediatric Education Discharge Support Strategies for Newly Diagnosed Children With Cancer.

Journal Article Cancer nursing · November 2021 BackgroundDischarge education practices vary among institutions and lack a standardized approach for newly diagnosed pediatric oncology patients and their parents.ObjectiveThe purpose of this American Nurses Credentialing Center-supported ... Full text Cite

Biomarkers and Cognitive Function in Children and Adolescents During Maintenance Therapy for Leukemia.

Journal Article Oncology nursing forum · November 2021 ObjectivesTo explore the relationship between biomarkers of oxidative stress and inflmmation in cerebrospinal fluid (CSF) and cognitive function in children receiving maintenance therapy for acute lymphocytic leukemia (ALL).Sample & settin ... Full text Cite

Prospective patient-reported symptom profiles associated with pediatric acute lymphoblastic leukemia relapse.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · May 2021 PurposeDespite improvements in frontline pediatric acute lymphoblastic leukemia (ALL) treatment, relapse remains a concern. Research in adult cancer patients suggests that patient-reported symptoms may predict survival, but the relationship betwee ... Full text Cite

Cerebrospinal Fluid Metabolomic Profiles Associated With Fatigue During Treatment for Pediatric Acute Lymphoblastic Leukemia.

Journal Article Journal of pain and symptom management · March 2021 ContextCancer-related fatigue (CRF) is one of the most distressing and persistent symptoms reported during pediatric acute lymphoblastic leukemia (ALL) therapy; however, information on the pathways underlying CRF severity is limited.Objectives ... Full text Cite

Improving Peripheral Intravenous Catheter Care for Children with Cancer Receiving Chemotherapy in Malawi.

Journal Article Journal of pediatric nursing · January 2021 PurposeTo change pediatric oncology nursing management of peripheral intravenous catheter (PIVC) insertion and care based on current best evidence.Design and methodsPractice change strategies were developed, and nurses completed education ... Full text Cite

Promoting pediatric oncology nursing excellence in sub-Saharan Africa using project ECHO

Journal Article International Journal of Africa Nursing Sciences · January 1, 2021 Purpose: The designation of the year 2020 as the International Year of the Nurse provides time for reflection on the importance of nursing in meeting the needs of the under-served throughout the world. The purpose of this project was to implement an educat ... Full text Cite

Distance-Based Education for Nurses Caring for Children With Cancer in Sub-Saharan Africa.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2020 Nursing specialization in the care of children with cancer provides the foundation for implementing successful childhood cancer and blood disorder treatment programs throughout the world. Excellence in nursing education is at the center of all that is need ... Full text Cite

The Longitudinal Parallel Process Analysis of Biomarkers of Oxidative Stress, Symptom Clusters, and Cognitive Function in Children With Leukemia.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2020 Background: During treatment for acute lymphoblastic leukemia (ALL), children report co-occurring symptoms of fatigue, sleep disturbance, pain, nausea, and depression as a symptom cluster. Central nervous system-directed ALL therapies also put child ... Full text Cite

Implementing a pediatric oncology nursing multisite trial.

Journal Article Journal for specialists in pediatric nursing : JSPN · July 2020 Purpose/backgroundThe Parent Educational Discharge Support Strategies (PEDSS) nursing study includes 16 magnet pediatric oncology institutions across the United States and one in Saudi Arabia, evaluating a nurse-led parent educational discharge su ... Full text Cite

Promoting Direct Care Nurse Engagement in Research in Magnet Hospitals: The Parent Education Discharge Support Strategies Experience.

Journal Article The Journal of nursing administration · May 2020 Multisite study participation provides an opportunity for hospitals to gain access to the resources required to facilitate nursing research. The nurse-led Parent Educational Discharge Support Strategies for children newly diagnosed with cancer (PEDSS) mult ... Full text Cite

Influence of Inflammatory and Oxidative Stress Pathways on Longitudinal Symptom Experiences in Children With Leukemia.

Journal Article Biological research for nursing · October 2019 PurposeThe purpose of this study was to explore the influence of oxidative stress (F2-isoprostanes) and inflammatory (interleukin [IL]-8) biomarkers on symptom trajectories during the first 18 months of childhood leukemia treatment.Method ... Full text Cite

Impact of Childhood Leukemia Treatment on Attention Measured by the Continuous Performance Test Factor Structure.

Journal Article Oncology nursing forum · July 2019 ObjectivesTo describe the impact of central nervous system-directed treatment on attention and its relation to academic outcomes in childhood acute lymphoblastic leukemia (ALL) survivors.Sample & setting51 children diagnosed with ALL ... Full text Cite

Perspectives of Childhood Cancer Symptom-Related Distress: Results of the State of the Science Survey.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2019 Management of symptom-related distress is an important area of pediatric oncology nursing. Participants who attended the Children's Oncology Group (COG) State of the Science Symposium on symptom distress completed an anonymous survey. The purpose was to ex ... Full text Cite

Symptom Assessment During Childhood Cancer Treatment.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2019 Full text Cite

Reimagine: a randomized controlled trial of an online, symptom self-management curriculum among breast cancer survivors.

Journal Article Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · May 2019 PurposeChronic pain, depression, and fatigue are common effects resulting from the cancer experience; new interventions are needed. This study examined the effect of Reimagine, an online symptom self-management curriculum that teaches coping skill ... Full text Cite

Sleep Evaluation in the Assessment of Pediatric Attention Deficit Disorders.

Journal Article Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners · May 2019 IntroductionExamining the impact of appropriate sleep evaluation on diagnosis of attention deficit disorders can improve the standard of care in pediatrics. This quality improvement project examined current practice and subsequent implementation o ... Full text Cite

Childhood Cancer Symptom Cluster: Leukemia and Health-Related Quality of Life.

Journal Article Oncology nursing forum · March 2019 ObjectivesTo examine the relationship of the Childhood Cancer Symptom Cluster-Leukemia (CCSC-L) with health-related quality of life (HRQOL).Sample & setting327 children receiving treatment for acute lymphoblastic leukemia from four pe ... Full text Cite

A Program to Enhance Writing Skills for Advanced Practice Nurses.

Journal Article Journal of continuing education in nursing · March 2019 BackgroundAdvanced practice RNs (APRNs) make important contributions to scholarly journals that are derived from scientific evidence and clinical practice. This article presents a writing program designed to enhance the writing skills of APRNs wit ... Full text Cite

Improving Transitional Care: The Role of Handoffs and Discharge Checklists in Hematologic Malignancies.

Journal Article Clinical journal of oncology nursing · February 2019 BackgroundTransitional care from inpatient to outpatient settings is a high-risk time for medical errors and missed follow-up appointments. Discharge checklists and handoffs are effective tools that lead to improved quality of care and outcomes. Full text Cite

What Do Breast Cancer Survivors Expect From Exercise?

Journal Article Cancer Nurs · 2019 BACKGROUND: Exercise outcome expectations (OEs) (ie, what one expects to obtain or avoid by exercising) are influential to increase exercise among cancer survivors. OBJECTIVE: The aim of this study was to measure the accessibility (ie, frequency one thinks ... Full text Link to item Cite

Physical Activity, the Childhood Cancer Symptom Cluster-Leukemia, and Cognitive Function: A Longitudinal Mediation Analysis.

Journal Article Cancer nursing · November 2018 BackgroundChildren undergoing leukemia treatment report co-occurring symptoms of fatigue, sleep disturbances, pain, nausea, and depression as a symptom cluster. Physical activity (PA) is essential for development and may influence symptom severity ... Full text Cite

A randomized phase II trial of MOVING ON: An intervention to increase exercise outcome expectations among breast cancer survivors.

Journal Article Psychooncology · October 2018 OBJECTIVE: The objective of the study is to test theoretical intervention fidelity and feasibility of MOVING ON, a self-directed, home-based, randomized controlled trial to increase exercise outcome expectations (OEs) (what one expects to obtain or avoid a ... Full text Link to item Cite

Peripheral neuropathy in children and adolescents treated for cancer.

Journal Article The Lancet. Child & adolescent health · October 2018 Peripheral neuropathy is a well recognised treatment-related toxicity in children with cancer, associated with exposure to neurotoxic chemotherapy agents. Acute damage can occur in sensory, motor, or autonomic neurons, with symptoms that are rarely life th ... Full text Cite

Disparities in Neurotoxicity Risk and Outcomes among Pediatric Acute Lymphoblastic Leukemia Patients.

Journal Article Clinical cancer research : an official journal of the American Association for Cancer Research · October 2018 Purpose: Methotrexate chemotherapy can be associated with neurologic complications during therapy and long-term neurologic deficits. This study evaluated demographic and clinical factors associated with incidence of methotrexate neurotoxicity and de ... Full text Cite

Changes in Oxidant Defense, Apoptosis, and Cognitive Abilities During Treatment for Childhood Leukemia.

Journal Article Biological research for nursing · July 2018 Aggressive central nervous system (CNS)-directed treatment for acute lymphoblastic leukemia (ALL), the most prevalent cancer among children and adolescents, prevents metastasis of leukemia cells into the brain. Up to 60% of survivors experience cognitive p ... Full text Cite

A Standardized Education Checklist for Parents of Children Newly Diagnosed With Cancer: A Report From the Children's Oncology Group.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2018 Parents of children newly diagnosed with cancer must acquire new knowledge and skills in order to safely care for their child at home. Institutional variation exists in the methods and content used by nurses in providing the initial education. The goal of ... Full text Cite

Influence of Nitrosative Stress on Fatigue During Childhood Leukemia Treatment.

Journal Article Biological research for nursing · July 2018 The focus on a cure for childhood leukemia over the last three decades has resulted in survival rates of more than 80%. However, efforts to manage leukemia-treatment symptoms have not kept pace with new therapies. Symptom toxicity during treatment can resu ... Full text Cite

Protocol for Moving On: a randomized controlled trial to increase outcome expectations and exercise among breast cancer survivors.

Journal Article Nurs Open · January 2018 AIM: The aim of this study was to test the feasibility and fidelity of an intervention, Moving On, aimed to increase outcome expectations OEs (i.e. what one expects to obtain or avoid as a result of a behaviour) and exercise among breast cancer survivors. ... Full text Link to item Cite

Perioperative Care Implementation: Evidence-Based Practice for Patients With Pancreaticoduodenectomy Using the Enhanced Recovery After Surgery Guidelines 
.

Journal Article Clinical journal of oncology nursing · August 2017 BackgroundPancreatic adenocarcinoma is an aggressive cancer that carries a poor prognosis. Pancreaticoduodenectomy (PD) offers the only potential cure, but the associated morbidity is high. The Enhanced Recovery After Surgery (ERAS) evidence-based ... Full text Cite

Symptom Trajectories in Children Receiving Treatment for Leukemia: A Latent Class Growth Analysis With Multitrajectory Modeling.

Journal Article Journal of pain and symptom management · July 2017 ContextCancer treatment symptoms play a major role in determining the health of children with cancer. Symptom toxicity often results in complications, treatment delays, and therapy dose reductions that can compromise leukemia therapy and jeopardiz ... Full text Cite

Declines Noted in Cognitive Processes and Association With Achievement Among Children With Leukemia.

Journal Article Oncology nursing forum · July 2017 Purpose/objectivesTo assess change in specific cognitive processes during treatment with chemotherapy only among children with acute lymphoblastic leukemia (ALL). 
.DesignA prospective, repeated measures design.
.SettingPediatric ... Full text Cite

Patient/Family Education as Translational Science in Pediatric Oncology.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · May 2017 Full text Cite

Patient/Family Education for Newly Diagnosed Pediatric Oncology Patients.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2016 There is a paucity of data to support evidence-based practices in the provision of patient/family education in the context of a new childhood cancer diagnosis. Since the majority of children with cancer are treated on pediatric oncology clinical trials, la ... Full text Cite

Understanding Effective Delivery of Patient and Family Education in Pediatric OncologyA Systematic Review From the Children's Oncology Group [Formula: see text].

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2016 A diagnosis of childhood cancer is a life-changing event for the entire family. Parents must not only deal with the cancer diagnosis but also acquire new knowledge and skills to care safely for their child at home. Best practices for delivery of patient/fa ... Full text Cite

Educating Families of Children Newly Diagnosed With Cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2016 Parents/caregivers require specialized education in order to care for their child with a newly diagnosed cancer. Currently, no evidence-based guidelines exist to identify content essential for inclusion in patient/family education prior to a child's initia ... Full text Cite

A nurse-driven process for timely removal of urinary catheters

Journal Article International Journal of Urological Nursing · November 1, 2016 Catheter-associated urinary tract infection (CAUTI) comprises 30–40% of all health care-acquired infections, and 70–80% of these infections are related with use of indwelling urinary catheters. This quality improvement (QI) project was initiated to evaluat ... Full text Cite

Fatigue and Oxidative Stress in Children Undergoing Leukemia Treatment.

Journal Article Biological research for nursing · October 2016 Fatigue is a frequent and distressing symptom in children undergoing leukemia treatment; however, little is known about factors influencing this symptom. Antioxidants such as glutathione can decrease symptom severity in adult oncology patients, but no stud ... Full text Cite

Neurocognitive Predictors of Academic Outcomes Among Childhood Leukemia Survivors.

Journal Article Cancer nursing · July 2016 BackgroundAcute lymphoblastic leukemia is the most common pediatric cancer, and survival approaches 90%. Acute lymphoblastic leukemia survivors are more likely than healthy peers or siblings to experience academic underachievement, yet little is k ... Full text Cite

Reconsidering Physical Activity Restrictions for Mononephric Survivors of Childhood Cancer: A Report From the Children's Oncology Group.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2016 Although traditional recommendations for mononephric childhood cancer survivors are to avoid contact sports in order to protect the remaining kidney, review of available evidence suggests that the majority of renal loss is caused by accidents not involving ... Full text Cite

Health Professions Education Research and the Institutional Review Board.

Journal Article Nurse Educ · 2016 The growth in health professions education (HPE) and a desire on the part of nurse and medical educators to disseminate their work have raised important questions about the ethical conduct of education research. At the center of the debate is the instituti ... Full text Link to item Cite

Evaluation of a Preoperative Clinic for Women With Gynecologic Cancer.

Journal Article Clinical journal of oncology nursing · December 2015 Although many patients with gynecologic cancer undergo surgery, time constraints during the preoperative consultation may affect the accuracy of the information exchange, as well as compromise the quality of the patient assessment and care plan. Both put p ... Full text Cite

Implementing a Daily Maintenance Care Bundle to Prevent Central Line-Associated Bloodstream Infections in Pediatric Oncology Patients.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2015 Eliminating central line-associated bloodstream infection (CLABSI) is a national priority. Central venous catheter (CVC) care bundles are composed of a series of interventions that, when used together, are effective in preventing CLABSI. A CVC daily mainte ... Full text Cite

Evaluation of Biomarkers of Oxidative Stress and Apoptosis in Patients With Severe Methotrexate Neurotoxicity: A Case Series.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2015 Central nervous system (CNS) treatment is an essential part of acute lymphocytic leukemia (ALL) therapy, and the most common CNS treatment is intrathecal (IT) and high-dose intravenous (IV) methotrexate (MTX). Treatment with MTX may cause neurotoxicity, wh ... Full text Cite

Oxidative Stress, Motor Abilities, and Behavioral Adjustment in Children Treated for Acute Lymphoblastic Leukemia.

Journal Article Oncology nursing forum · September 2015 Purpose/objectivesTo examine associations among oxidative stress, fine and visual-motor abilities, and behavioral adjustment in children receiving chemotherapy for acute lymphoblastic leukemia (ALL)
.DesignA prospective, repeated-measures ... Full text Cite

Health-Related Quality of Life among Children and Adolescents during Hematopoietic Stem Cell Transplant Recovery.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2015 Health-related quality of life (HRQoL) has been noted to fluctuate among children during hematopoietic stem cell transplant (HSCT) recovery; however, the specific timing and associations of these changes are poorly understood. This repeated-measures study ... Full text Cite

Venous Thromboembolism Risk Assessment and Prophylaxis Use in Pediatric, Adolescent, and Young Adult Hematology Oncology Patients.

Journal Article Journal of pediatric hematology/oncology · August 2015 No widely accepted method exists to evaluate pediatric hematology oncology patients for the risk of venous thromboembolism (VTE) and the need for prophylaxis. The use of a VTE risk-assessment tool and standardized guidelines for prophylaxis could increase ... Full text Cite

Trajectories of Obesity and Overweight Rates Among Survivors of Childhood Acute Lymphoblastic Leukemia.

Journal Article Oncology nursing forum · July 2015 Purpose/objectivesTo describe the trajectories of obesity/overweight rates by age group among survivors of childhood acute lymphoblastic leukemia (ALL) from diagnosis through several years post-therapy.DesignLongitudinal, descriptive. ... Full text Cite

Improving Adherence to Evidence-Based Guidelines for Chemotherapy-Induced Nausea and Vomiting.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2015 Chemotherapy-induced nausea and vomiting (CINV) is one of the most common side effects experienced by patients receiving chemotherapy. Antiemetic medications can be used to effectively prevent and treat CINV. Choice and dose of antiemetics are often based ... Full text Cite

Increase in oxidative stress as measured by cerebrospinal fluid lipid peroxidation during treatment for childhood acute lymphoblastic leukemia.

Journal Article Journal of pediatric hematology/oncology · March 2015 Five-year survival from childhood acute lymphoblastic leukemia (ALL) approaches 90%, but 40% of survivors experience central nervous system (CNS) treatment-related cognitive problems. Despite considerable evidence for cognitive problems, less is known abou ... Full text Cite

Fatigue and carnitine levels over multiple cycles of chemotherapy in children and adolescents.

Journal Article European journal of oncology nursing : the official journal of European Oncology Nursing Society · February 2015 PurposeFatigue in childhood cancer is a pervasive and distressing symptom described as a "lack of energy". Carnitine is a micronutrient used to transport long chain fatty acids into muscle mitochondria. Some chemotherapy drugs interfere with the c ... Full text Cite

Evidence-Based Practice Projects in Pediatric Oncology Nursing.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2014 This introduction article discusses the history and importance of evidence-based practice, along with describing the process that 6 nurse-led teams completed for the systematic reviews listed in this journal issue. ... Full text Cite

The influence of oxidative stress on symptom occurrence, severity, and distress during childhood leukemia treatment.

Journal Article Oncology nursing forum · July 2014 Purpose/objectivesTo explore the symptom trajectory during the first 16 months of childhood leukemia treatment and any associations with the oxidative stress pathway measured by cerebrospinal fluid (CSF) concentration of oxidized phosphatidylcholi ... Full text Cite

Neutropenia Precautions for Children Receiving Chemotherapy or Stem Cell Transplantation for Cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2014 Infections in children and adolescents with cancer are a significant cause of morbidity and mortality, especially in those receiving chemotherapy who are neutropenic and/or immunocompromised. The aim of this article is to review existing evidence in order ... Full text Cite

F2-isoprostanes: a measure of oxidative stress in children receiving treatment for leukemia.

Journal Article Biological research for nursing · July 2014 Acute lymphoblastic leukemia (ALL) is the most prevalent and curable cancer among children and adolescents less than 15 years of age in the United States. Essential for cure of childhood ALL is prophylactic treatment of the central nervous system (CNS), wi ... Full text Cite

Symptom prevalence and physiologic biomarkers among adolescents using a mobile phone intervention following hematopoietic stem cell transplantation.

Journal Article Oncology nursing forum · May 2014 Purpose/objectivesTo examine symptom reports and physiologic parameters in adolescents using the Eating After Transplant (EAT!) intervention during recovery after hematopoietic stem cell transplantation (HSCT).DesignRepeated measures desi ... Full text Cite

Standardization of health care provider competencies for intrathecal access procedures.

Journal Article J Pediatr Oncol Nurs · 2014 INTRODUCTION: This quality improvement (QI) project addresses a method for experienced health care providers to maintain skill-based competence for intrathecal access procedures. METHODS: A prospective QI design using intrathecal access simulation to asses ... Full text Open Access Link to item Cite

Cancer-related cognitive changes in children, adolescents and adult survivors of childhood cancers.

Journal Article Seminars in oncology nursing · November 2013 ObjectivesTo summarize the current knowledge about 1) cognitive changes associated with central nervous system-directed chemotherapy and cranial radiation among children with acute lymphoblastic leukemia and brain tumors and adult survivors; and 2 ... Full text Cite

Feasibility of a symptom management intervention for adolescents recovering from a hematopoietic stem cell transplant.

Journal Article Cancer nursing · September 2013 BackgroundAdolescents undergoing a hematopoietic stem cell transplantation (HSCT) experience a variety of adverse effects and eating difficulties. Few interventions exist to assist patients with self-care after HSCT hospitalization. The Eating Aft ... Full text Cite

Symptom clusters in children.

Journal Article Current opinion in supportive and palliative care · March 2013 Purpose of reviewResearchers have focused on identifying and describing symptom experiences among children with various diseases but symptoms can have a synergistic and/or an antecedent effect that must be evaluated. This review reports the curren ... Full text Cite

Mathematics intervention for prevention of neurocognitive deficits in childhood leukemia.

Journal Article Pediatric blood & cancer · August 2012 BackgroundDespite evidence that CNS treatment is associated with cognitive and academic impairment, interventions to prevent or mitigate these problems are limited. The purpose was to determine if early intervention can prevent declines in mathema ... Full text Cite

Chemotherapy-related changes in central nervous system phospholipids and neurocognitive function in childhood acute lymphoblastic leukemia.

Journal Article Leukemia & lymphoma · August 2012 Long-term survivors of childhood leukemia are at risk for neurocognitive impairment, although the neurophysiological basis is not well understood. The purpose of this study was to explore associations between changes in cerebrospinal fluid (CSF) phospholip ... Full text Cite

An outpatient Urgent Care Bay within a pediatric cancer and hematology center.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2012 Time-sensitive medical care is essential for pediatric patients undergoing treatment for a hematologic or oncologic condition. Such patients commonly experience acute symptoms related to routine childhood illness and/or their underlying disease or therapy. ... Full text Cite

Nausea and vomiting perspectives among children receiving moderate to highly emetogenic chemotherapy treatment.

Journal Article Cancer nursing · May 2012 BackgroundChemotherapy-induced nausea and vomiting (CINV) are common adverse effects, but occurrences among pediatric oncology patients are not well documented.ObjectiveThe primary aim was to describe anticipatory, acute, and delayed CINV ... Full text Cite

Children's coping strategies for chemotherapy-induced nausea and vomiting.

Journal Article Oncology nursing forum · March 2012 Purpose/objectivesTo identify anticipatory, acute, and delayed chemotherapy-induced nausea and vomiting (CINV) frequency and coping strategies used among pediatric patients with cancer.DesignProspective, cohort design.SettingA pe ... Full text Cite

Lipid profiles of pediatric hematopoietic stem cell transplant survivors.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · March 2012 Cardiovascular disease (CVD) is the leading cause of death among adults in the United States. CVD pathology, including abnormal lipid levels, may begin in childhood. Hematopoietic stem cell transplant (HSCT) survivors have increased risk of abnormal lipid ... Full text Cite

Using improvement science to promote evidence-based practice in a childhood cancer and hematology center.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · January 2012 A major children's cancer and hematology center established a Quality Transformation (QT) Core to develop and monitor empirical outcomes that demonstrate excellence in clinical care. The QT Core, based on the Institute of Medicine's domains of quality heal ... Full text Cite

Nausea, pain, fatigue, and multiple symptoms in hospitalized children with cancer.

Journal Article Oncology nursing forum · September 2011 Purpose/objectivesTo describe the prevalence, frequency, severity, and distress of multiple symptoms in hospitalized children with cancer and to examine the overall symptom scores and global distress in patients reporting nausea, pain, and fatigue ... Full text Cite

Psychometric and clinical assessment of the 13-item reduced version of the fatigue scale-adolescent instrument.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2011 Fatigue is one of the most common and distressing symptoms experienced by adolescents during and after treatment for cancer. The lack of reliable and valid instruments has prevented an accurate assessment of the trajectory of fatigue among adolescent oncol ... Full text Cite

Sickness behavior clustering in children with cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · September 2011 Despite knowing that pediatric cancer patients experience multiple concurrent symptoms, most research focuses on individual symptoms. This study is a secondary data analysis from previous research evaluating symptom clusters and carnitine plasma levels in ... Full text Cite

The impact of an arts program in a children's cancer and hematology center.

Journal Article Arts & Health · September 2011 The Arts in Medicine (AIM) program is an established, 13-year-old program in a major children's Cancer and Hematology Center that provides meaningful artistic opportunities to cancer patients and their families in inpatient and outpatient settings. We rep ... Full text Cite

Managing painful procedures in children with cancer.

Journal Article Journal of pediatric hematology/oncology · March 2011 Children with cancer experience repeated invasive and painful medical procedures. Pain and distress does not decrease with repeated procedures and may worsen if pain is not adequately managed. In 1990, the first recommendations on the management of pain an ... Full text Cite

Improving care for children with sickle cell disease/acute chest syndrome.

Journal Article Pediatrics · February 2011 BackgroundAcute chest syndrome (ACS) is a leading cause of hospitalization and death of children with sickle cell disease (SCD). An evidence-based ACS/SCD guideline was established to standardize care throughout the institution in February 2008. H ... Full text Cite

Fatigue

Chapter · January 1, 2011 Full text Cite

Review of chronic graft-versus-host disease in children after allogeneic stem cell transplantation: nursing perspective.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · January 2011 This review presents a summary of the research literature related to the incidence and risk factors for chronic graft-versus-host disease in children following allogeneic hematopoietic stem cell transplantation. The range of incidence of chronic graft-vers ... Full text Cite

Mechanisms of dexamethasone-induced disturbed sleep and fatigue in paediatric patients receiving treatment for ALL.

Journal Article European journal of cancer (Oxford, England : 1990) · July 2010 BackgroundDexamethasone contributes to high cure rates in paediatric acute lymphoblastic leukaemia (ALL) but significantly and adversely alters sleep and fatigue. Herein we explored three mechanisms (pharmacokinetics, serum albumin and pharmacogen ... Full text Cite

The meaning of adolescents' eating experiences during bone marrow transplant recovery.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · March 2010 Bone marrow transplant (BMT) is a common treatment option for adolescents with various diseases; however, the aggressive therapy often causes significant side effects that can lead to poor eating. There is little documentation of eating experiences and nec ... Full text Cite

Oxidative stress and neurobehavioral problems in pediatric acute lymphoblastic leukemia patients undergoing chemotherapy.

Journal Article Journal of pediatric hematology/oncology · March 2010 Neurobehavioral problems after chemotherapy treatment for pediatric acute lymphoblastic leukemia (ALL) have been a recent focus of investigation. This study extended previous research that suggested oxidative stress as a potential mechanism for chemotherap ... Full text Cite

Psychometric and clinical assessment of the 10-item reduced version of the Fatigue Scale-Child instrument.

Journal Article Journal of pain and symptom management · March 2010 Fatigue is one of the most debilitating conditions associated with cancer and anticancer therapy. The lack of reliable and valid self-report instruments has prevented accurate assessment of fatigue in pediatric oncology patients. The purpose of this study ... Full text Cite

Symptom clusters in children and adolescents receiving cisplatin, doxorubicin, or ifosfamide.

Journal Article Oncology nursing forum · January 2010 Purpose/objectivesTo examine the influence of the proposed symptom cluster of fatigue, nausea and vomiting, and sleep disturbances on clinical outcomes defined as behavior changes, depression, and performance status in children and adolescents bef ... Full text Cite

Oxidative stress and executive function in children receiving chemotherapy for acute lymphoblastic leukemia.

Journal Article Pediatric blood & cancer · October 2009 BackgroundNeurocognitive sequelae following treatment for pediatric acute lymphoblastic leukemia (ALL) has been reported in a significant proportion of survivors, including those treated only with chemotherapy. Early identification of children "at ... Full text Cite

Carnitine plasma levels and fatigue in children/adolescents receiving cisplatin, ifosfamide, or doxorubicin.

Journal Article Journal of pediatric hematology/oncology · September 2009 Fatigue is the most frequent symptom experienced by children/adolescents with cancer. One mechanism contributing to cancer-related fatigue involves abnormalities in adenosine triphosphate synthesis caused by carnitine deficiency. The purpose of this study ... Full text Cite

Reducing central venous catheter-related bloodstream infections in children with cancer.

Journal Article Oncology nursing forum · March 2009 Purpose/objectivesTo determine whether a comprehensive educational program influenced the incidence of hub colonization of central venous catheters (CVCs) and bloodstream infection rates in children with cancer, to identify risk factors related to ... Full text Cite

Creating an evidence-based practice environment: one hospital's journey.

Journal Article Journal of trauma nursing : the official journal of the Society of Trauma Nurses · January 2009 There is increasing effort in promoting evidence-based practice (EBP) that supports the best possible care to patients and families. This article describes essential concepts for developing an environment of EBP and its implementation at a large pediatric ... Full text Cite

Teaching evidence-based practice skills in a hospital.

Journal Article Journal of continuing education in nursing · January 2009 Nurses and allied health professionals have the unique opportunity to become empowered through evidence-based practice (EBP) to make significant differences in the lives of patients and their families. Best practices in patient care occur only when staff c ... Full text Cite

Effects of patient controlled analgesia hydromorphone during acute painful episodes in adolescents with sickle cell disease: A pilot study

Chapter · October 1, 2008 The use of hydromorphone is increasing but little is known about its effects during painful episodes in adolescents with sickle cell disease. This pilot study examined the intensity, location, and quality of pain and evaluated the amount of relief and side ... Cite

Analgesic response to morphine in children with sickle cell disease: A pilot study

Chapter · October 1, 2008 Morphine given by Patient Controlled Analgesia (PCA) is widely used in hospital settings to manage severe pain during acute painful episodes. Wide variations in prescription patterns occur and some patients are often self-administering sub- or low- therape ... Cite

Growth patterns and gastrointestinal symptoms in pediatric patients after hematopoietic stem cell transplantation.

Journal Article Oncology nursing forum · May 2008 Purpose/objectivesTo identify growth patterns and gastrointestinal (GI) symptoms in pediatric patients during the first four months after hematopoietic stem cell transplantation (HSCT) and to assess whether an association exists between acute graf ... Full text Cite

Methotrexate-induced alterations in beta-oxidation correlate with cognitive abilities in children with acute lymphoblastic leukemia.

Journal Article Biological research for nursing · April 2008 Treatment advances, including central nervous system (CNS) treatment with methotrexate, have led to significant gains in disease-free survival from childhood acute lymphoblastic leukemia (ALL). However, methotrexate has been associated with neurological pr ... Full text Cite

Intensity, location, and quality of pain in Spanish-speaking children with cancer.

Journal Article Pediatric nursing · January 2008 Spanish speaking children with cancer were asked to describe their pain during the previous week prior to an oncology clinic appointment. Data showed that 41% of the children were experiencing pain and the overall mean pain intensity rating among these chi ... Cite

Validity and reliability of a new instrument to measure cancer-related fatigue in adolescents.

Journal Article Journal of pain and symptom management · December 2007 Adolescents undergoing treatment for cancer rate fatigue as their most prevalent and intense cancer- and treatment-related effect. Parents and staff rate it similarly. Despite its reported prevalence, intensity, and distressing effects, cancer-related fati ... Full text Cite

Dexamethasone alters sleep and fatigue in pediatric patients with acute lymphoblastic leukemia.

Journal Article Cancer · November 2007 BackgroundDexamethasone improves the cure rate of childhood acute lymphoblastic leukemia (ALL) but causes physical and behavioral adverse events. The objective of the current study was to determine the effect of dexamethasone exposure on sleep and ... Full text Cite

Longitudinal evaluation of fine motor skills in children with leukemia.

Journal Article Journal of pediatric hematology/oncology · August 2007 BackgroundImproved survival for children with acute lymphocytic leukemia (ALL) has allowed investigators to focus on the adverse or side effects of treatment and to develop interventions that promote cure while decreasing the long-term effects of ... Full text Cite

Variations in pain, sleep, and activity during hospitalization in children with cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 2007 This study examines the pain experiences of children with cancer during hospitalization. A descriptive design with repeated measures was used to describe the location, intensity, and quality of pain, pain medications, amount of pain relief, and perceptions ... Full text Cite

Creating an evidence-based practice environment: one hospital's journey.

Journal Article Journal of nursing care quality · July 2007 There is increasing effort in promoting evidence-based practice (EBP) that supports the best possible care to patients and families. This article describes essential concepts for developing an environment of EBP and its implementation at a large pediatric ... Full text Cite

Clinical field testing of an enhanced-activity intervention in hospitalized children with cancer.

Journal Article Journal of pain and symptom management · June 2007 This prospective, two-site, randomized, controlled pilot study assessed the feasibility of an enhanced physical activity (EPA) intervention in hospitalized children and adolescents receiving treatment for a solid tumor or for acute myeloid leukemia (AML), ... Full text Cite

Symptom clusters in children with cancer.

Journal Article Seminars in oncology nursing · May 2007 ObjectivesTo discuss the symptoms of fatigue, sleep disturbance, and pain in children undergoing cancer treatment, and a framework for the clustering of these symptoms.Data sourcesPublished articles, research studies, and clinical experie ... Full text Cite

Brief report: effect of intravenous methotrexate dose and infusion rate on neuropsychological function one year after diagnosis of acute lymphoblastic leukemia.

Journal Article Journal of pediatric psychology · March 2007 ObjectiveTo compare the effects of two intravenous (IV) methotrexate (MTX) infusion protocols on cognitive function in children newly diagnosed with acute lymphoblastic leukemia (ALL).MethodsWe compared 19 children treated with 1 g/m(2) o ... Full text Cite

Nocturnal awakenings, sleep environment interruptions, and fatigue in hospitalized children with cancer.

Journal Article Oncology nursing forum · March 2007 Purpose/objectivesTo describe nocturnal awakenings and sleep environment interruptions experienced by children and adolescents hospitalized for two to four days to receive chemotherapy and to assess the relationships among nocturnal awakenings, sl ... Full text Cite

Double-blind, placebo-controlled study of quality of life, hematologic end points, and safety of weekly epoetin alfa in children with cancer receiving myelosuppressive chemotherapy.

Journal Article Journal of clinical oncology : official journal of the American Society of Clinical Oncology · August 2006 PurposeTo evaluate the effects of once-weekly epoetin alfa (EPO) on health-related quality of life (HRQOL), hemoglobin (Hb), transfusions, and tolerability in children with cancer.MethodsAnemic patients 5 years to 18 years of age receivin ... Full text Cite

Implementing evidence-based nursing practice in a pediatric hospital.

Journal Article Pediatric nursing · July 2006 A commonly stated reason for dissatisfaction among nurses is that their input regarding patient care and suggestions for improvement in the workplace environment are not solicited or recognized. Nurses can have an active voice in their practice by using th ... Cite

In reply [8]

Journal Article Journal of Clinical Oncology · May 1, 2006 Full text Cite

Decision making in pediatric oncology: who should take the lead? The decisional priority in pediatric oncology model.

Journal Article Journal of clinical oncology : official journal of the American Society of Clinical Oncology · January 2006 Decision making in pediatric oncology can look different to the ethicist and the clinician. Popular ethical theories argue that clinicians should not make decisions for patients, but rather provide information so that patients can make their own decisions. ... Full text Cite

Oxidative changes in cerebral spinal fluid phosphatidylcholine during treatment for acute lymphoblastic leukemia.

Journal Article Biological research for nursing · January 2005 Central nervous system (CNS) treatment contributes to improved long-term disease-free survival from childhood acute lymphoblastic leukemia (ALL) by significantly decreasing the rate of disease relapse. Methotrexate (MTX), a drug commonly used for CNS treat ... Full text Cite

Symptom management research in children with cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · May 2004 A review of the clinical research studies published within the past 5 years revealed that efforts to manage symptoms of cancer and its treatments have not kept pace with new advances in the cure for cancer. Children with cancer continue to experience distr ... Full text Cite

Online exclusive: functional integration of nursing research into a pediatric oncology cooperative group: finding common ground.

Journal Article Oncology nursing forum · November 2003 Purpose/objectivesTo provide a brief description of the historic role of nursing and nursing research in the culture of previous pediatric oncology cooperative groups and compare the research language used in cooperative groups with the language u ... Full text Cite

Sense of humor, childhood cancer stressors, and outcomes of psychosocial adjustment, immune function, and infection.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · November 2003 The diagnosis, treatment, and side effects of childhood cancer have been described as extremely stressful experiences in the life of a child. Anecdotally, children report that a sense of humor helps them cope with the daily experiences of living with cance ... Full text Cite

Pediatric oncology nursing.

Journal Article Journal of pediatric nursing · April 2003 We are pleased to publish this special issue on pediatric oncology nursing. The articles in this issue provide readers with the most current clinical updates on the treatment and care of children and youth with childhood cancer. We thank Dr. Marilyn Hocken ... Full text Cite

Three instruments to assess fatigue in children with cancer: the child, parent and staff perspectives.

Journal Article Journal of pain and symptom management · April 2003 The purpose of this study was to develop and test three instruments to measure fatigue in children with cancer from the perspectives of the child, parents and staff. The study consisted of three phases: instrument development, content validation, and estim ... Full text Cite

Incidence of anemia in children with solid tumors or Hodgkin disease.

Journal Article Journal of pediatric hematology/oncology · January 2002 Anemia is a hematologic abnormality commonly discussed during the treatment of childhood cancer, but its incidence has not been previously reported. As the basis for determining the incidence of anemia, this retrospective review of medical records combined ... Full text Cite

Consensus statements: analyzing a new model to evaluate fatigue in children with cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · May 2001 Fatigue may be a universal experience for children and adolescents who are being treated for a malignancy. Sadly, it may also be the most unrecognized and thus unaddressed symptom experienced by this population. Giving adequate attention to this symptom ha ... Cite

Developing a research program on fatigue in children and adolescents diagnosed with cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · May 2001 Fatigue may be a universal experience for children and adolescents who are being treated for a malignancy. Sadly, it may also be the most unrecognized and thus unaddressed symptom experienced by this population. Giving adequate attention to this symptom ha ... Cite

Fatigue in children and adolescents with cancer: evolution of a program of study.

Journal Article Seminars in oncology nursing · November 2000 OBJECTIVE: To describe the development of a research program focused on cancer-related fatigue in children and adolescents and the resulting definition and model. METHODS: Research studies, review articles, and clinical examples. CONCLUSIONS: Fatigue has b ... Cite

Comparing patient, parent, and staff descriptions of fatigue in pediatric oncology patients.

Journal Article Cancer nursing · August 1999 Fatigue in children and adolescents with cancer is a disruptive symptom meriting clinical intervention by nurses, but has eluded definition, measurement, and intervention. Fatigue in these patients exists within a greater context of illness, treatment, and ... Cite

Fatigue in 7- to 12-year-old patients with cancer from the staff perspective: an exploratory study.

Journal Article Oncology nursing forum · March 1999 OBJECTIVE: To document and analyze the perspectives of staff members who provide direct care to 7- to 12-year-old patients with cancer regarding the nature and characteristics of fatigue, causes of fatigue, and effective interventions for this population o ... Cite

Communication about sexual issues: mothers, fathers, and friends.

Journal Article The Journal of adolescent health : official publication of the Society for Adolescent Medicine · March 1999 OBJECTIVE: To identify the content, characteristics, and comfort level of discussions about sexuality held between mothers and their early adolescent children and to determine the extent to which the conversations predicted sexual values and initiation of ... Cite

Developing a conceptual model for fatigue in children.

Journal Article European Journal of Oncology Nursing · March 1999 The purpose of this research study was to define fatigue experienced by children with cancer and to begin development of a conceptual model.Two major Paediatric Cancer Centers in the Southern USA participated in this study. Children who participated in thi ... Full text Link to item Cite

Fatigue in children and adolescents with cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 1998 Fatigue is a common symptom found in the adult oncology literature. However, little is known about its occurrence, causes, conceptual and operational definitions, and effective interventions in children and adolescents with cancer. The purpose of this stud ... Cite

Methylobacterium mesophilica as a cause of persistent bacteremia in a child with lymphoma.

Journal Article The Pediatric infectious disease journal · October 1997 Fatigue is a common symptom found in the adult oncology literature. However, little is known about its occurrence, causes, conceptual and operational definitions, and effective interventions in children and adolescents with cancer. The purpose of this stud ... Cite

Development of two instruments examining stress and adjustment in children with cancer.

Journal Article Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses · July 1997 The childhood cancer literature provides limited understanding of the school-age child's perception of cancer stressors and factors that contribute to adjustment in the midst of these stressors. This study evaluated the reliability and validity of two ques ... Cite

Therapeutic trial for infant acute lymphoblastic leukemia: the Pediatric Oncology Group experience (POG 8493).

Journal Article Journal of pediatric hematology/oncology · April 1997 OBJECTIVE: Despite improved event-free survival of older children with acute lymphocytic leukemia (ALL), infants 50,000/microl), and a higher likelihood of CD-10 (CALLA) negative lymphoblasts (55%). A translocation involving chromosome 11 at band q23 was d ... Cite

The content of African American mothers' discussions with their adolescents about sex.

Journal Article Journal of Family Nursing · November 1996 Abstract: Using a focus group approach, the investigators sought to explore the role of African American mothers in the education of their adolescents about sexuality including the provision of factual information and transmission of values. A focus group ... Cite

Psychosocial protocol for childhood cancer. A conceptual model.

Journal Article Cancer · September 1996 OBJECTIVE: Despite improved event-free survival of older children with acute lymphocytic leukemia (ALL), infants 50,000/microl), and a higher likelihood of CD-10 (CALLA) negative lymphoblasts (55%). A translocation involving chromosome 11 at band q23 was d ... Full text Cite

Managing treatment related side effects of nausea and vomiting.

Journal Article Cancer practice · August 1995 As part of a larger study on the impact of personal and family characteristics on adolescents' HIV risk and risk-reduction behavior, 90 adolescents and 73 mothers were asked to define in their own words seven terms related to sexual development: ejaculatio ... Full text Cite

Resources for care.

Journal Article Cancer · May 1993 No abstract. Brief report on resource constraints on care of children with cancer in U.S., with recommendations on subjects such as access &U cost containment ... Cite

Childhood cancers: incidence, etiology, diagnosis, and treatment.

Journal Article Pediatric nursing · May 1990 Treatment advances over the last few decades have dramatically increased survival for children with cancer. More than half the children treated for cancer are now cured. Consequently, professionals working with these children are beginning to focus on mini ... Cite

Systemic doxorubicin and intraarterial cisplatin preoperative chemotherapy plus postoperative adjuvant chemotherapy in patients with osteosarcoma.

Journal Article Cancer · March 1, 1989 The role of adjuvant chemotherapy for osteosarcoma has been well defined. Recently, the use of preoperative chemotherapy has been further enhanced by the use of intraarterial cisplatin. The authors describe the use and results of systemic doxorubicin and i ... Full text Link to item Cite

Experience with minimal complications in implanted catheters in children.

Journal Article Am J Pediatr Hematol Oncol · 1989 Eighty-two patients, ranging in age from 11 months to 24 years, underwent the percutaneous placement of an implanted catheter in order to have improved venous access. Thirty-five patients (43%) were beginning chemotherapy for cancer, four (5%) had a chroni ... Link to item Cite

Evaluating anemia in children.

Journal Article The Journal of practical nursing · March 1988 Cite

Limb salvage procedures in children with osteosarcoma.

Journal Article Cancer nursing · February 1988 Cite

Relaxation techniques in children with cancer: the nurse's role.

Journal Article Journal of the Association of Pediatric Oncology Nurses · January 1988 Full text Cite

Intra-arterial cisplatinum in preparation for the limb salvage procedure.

Journal Article Journal of the Association of Pediatric Oncology Nurses · January 1988 Full text Cite

Isolated vocal cord hematoma in a child with severe factor VIII deficiency.

Journal Article Southern medical journal · February 1987 We have reported the first case of isolated submucosal hematoma of the true vocal cord in a hemophilic patient. He was managed with factor VIII replacement therapy as an outpatient for five consecutive days, without complication. Similar but more serious c ... Full text Cite

Self-hypnosis as antiemetic therapy in children receiving chemotherapy.

Journal Article Oncology nursing forum · July 1985 Cite

Hypnosis as adjuvant antiemetic therapy in childhood cancer.

Journal Article The Nursing clinics of North America · March 1985 Hypnosis, as a relaxation technique to reduce anxiety and drug-related nausea and vomiting in children with cancer, is an effective treatment modality. Its benefit as a self-relaxation technique is now being realized. ... Cite

The curative potential of central nervous system (CNS) relapse in childhood acute lymphocytic leukemia (A.L.L.)

Journal Article Proceedings of the American Society of Clinical Oncology · January 1, 1982 Cite