Journal ArticleAging Cell · January 2024
Lack of exercise contributes to systemic inflammation and is a major cause of chronic disease. The long-term impact of initiating and sustaining exercise in late life, as opposed to sustaining a sedentary lifestyle, on whole-body health measures such as ph ...
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Journal ArticleStress Health · September 2023
The objectives of this article are to introduce a conceptual framework for physical resilience in the context of ageing and to discuss key elements and challenges in the design of studies of physical resilience after health stressors. Advancing age is asso ...
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Journal ArticleTelemed J E Health · June 2023
Background: Literature on telehealth interventions for older adults has been primarily on asynchronous interventions. During the COVID-19 pandemic, older adult exercise programs transitioned to an online format. This systematic review and case study examin ...
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Journal ArticleTransplant Cell Ther · August 2022
Allogeneic hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for both malignant and nonmalignant hematologic diseases; however, reported rates of treatment-related mortality approach 30%. Outcomes are worse in patients who b ...
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Journal ArticleValue Health · April 2022
OBJECTIVES: This study aimed to evaluate the cost-effectiveness of the randomized clinical trial STEP-KOA (STepped Exercise Program for patients with Knee OsteoArthritis). METHODS: The trial included 230 intervention and 115 control participants from 2 Vet ...
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Journal ArticlePilot and feasibility studies · March 2022
BackgroundThe life expectancy for individuals with sickle cell disease (SCD) has greatly increased over the last 50 years. Adults with SCD experience multiple complications such as cardiopulmonary disease, strokes, and avascular necrosis that lead ...
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Journal ArticleTransl Behav Med · December 14, 2021
Older veterans with posttraumatic stress disorder (PTSD) are at increased risk of obesity and cardiometabolic disease. Physical activity and healthy eating are two behaviors that impact health, functional independence, and disease risk in later life, yet f ...
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Journal ArticleArch Rehabil Res Clin Transl · September 2021
OBJECTIVE: To determine the reliability of 3 physical performance tests performed via a telehealth visit (30-s arm curls test, 30-s chair stand test, 2-min step test) among community-dwelling older veterans. DESIGN: Cross sectional study. SETTING: Virtual. ...
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Journal ArticleJ Am Geriatr Soc · July 2021
BACKGROUND: Understanding the factors that influence hospital mobility, especially in the context of a heightened focus on falls prevention, is needed to improve care. OBJECTIVE: This qualitative study uses a socioecological framework to explore factors th ...
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Journal ArticleJ Am Geriatr Soc · April 2021
OBJECTIVE: Post-traumatic stress disorder (PTSD) is common in Veterans. Symptoms can perpetuate into late life, negatively impacting physical and mental health. Exercise and social support are beneficial in treating anxiety disorders such as PTSD in the ge ...
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Journal ArticleAnn Intern Med · March 2021
BACKGROUND: Evidence-based models are needed to deliver exercise-related services for knee osteoarthritis efficiently and according to patient needs. OBJECTIVE: To examine a stepped exercise program for patients with knee osteoarthritis (STEP-KOA). DESIGN: ...
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Journal ArticleFront Sports Act Living · 2021
Purpose: Despite the potential for commercial activity devices to promote moderate to vigorous physical activity (MVPA), limited information is available in older adults, a high-priority target population with unique gait dynamics and energy expenditure. T ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · October 15, 2020
BACKGROUND: Military veterans living with post-traumatic stress disorder (PTSD) face significant physical and functional health disparities, which are often aggravated over time and in the context aging. Evidence has shown that physical activity can positi ...
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Journal ArticleJ Appl Gerontol · October 2020
Behavior change theory was used to explore predictors of long-term adherence (≥2 years) to exercise. A retrospective analysis of data from participants (N = 97) who reached a 6-month follow-up, which served as the baseline, was evaluated for completion of ...
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Journal ArticleJ Behav Med · August 2020
Exercise training positively impacts mental health, yet remains untested in older adults with posttraumatic stress disorder (PTSD). We conducted a randomized controlled pilot trial to test the feasibility and acceptability of exercise training in older vet ...
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Journal ArticleJ Aging Phys Act · April 24, 2020
This study describes the availability of physical activity information in the electronic health record, explores how electronic health record documentation correlates with accelerometer-derived physical activity data, and examines whether measured physical ...
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Journal ArticleJ Am Geriatr Soc · February 2020
BACKGROUND: Hospital-acquired disability (HAD) is common and often related to low physical activity while in the hospital. OBJECTIVE: To examine whether wearable hospital activity trackers can be used to predict HAD. DESIGN: A prospective observational stu ...
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Journal ArticleGerontology & geriatrics education · January 2020
Formal educational training in physical activity promotion is relatively sparse throughout the medical education system. The authors describe an innovative clinical experience in physical activity directed at medical clinicians on a geriatrics rotation. Th ...
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Journal ArticlePilot and feasibility studies · January 2020
BackgroundThe life expectancy for people with sickle cell disease (SCD) has improved tremendously over the last 50 years. This population experiences hemolysis and vaso-occlusion in multiple organs that lead to complications such as cardiopulmonar ...
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Journal ArticleGerontol Geriatr Med · 2020
Exercise is touted as the ideal prescription to treat and prevent many chronic diseases. We examined changes in utilization and cost of medication classes commonly prescribed in the management of chronic conditions following participation in 12-months of s ...
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Journal ArticleGerontol Geriatr Med · 2020
Exercise is critical for health maintenance in late life. The COVID-19 shelter in place and social distancing orders resulted in wide-scale interruptions of exercise therapies, placing older adults at risk for the consequences of decreased mobilization. Th ...
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Journal ArticleJ Aging Phys Act · December 1, 2019
Veterans represent a unique population of older adults as they are more likely to self-report disability and be overweight or obese compared to the general population. We sought to compare changes in mobility function across the obesity spectrum in older V ...
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Journal ArticleCancer · December 1, 2019
BACKGROUND: Cancer, its treatment, and associated adverse effects may accelerate the functional aging of cancer survivors. In the current study, the authors used geriatric assessment (GA) to compare the functional age of long-term cancer survivors with tha ...
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Journal ArticleJ Gen Intern Med · November 2019
BACKGROUND: Functional limitations may be more common in middle-aged adults than previously recognized. However, there are few published data on the prevalence of activity limitations, and their association with multimorbidity, among adults 50 to 64Â years ...
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Journal ArticleJAMA Netw Open · October 2, 2019
IMPORTANCE: Gait speed is a well-known indicator of risk of functional decline and mortality in older adults, but little is known about the factors associated with gait speed earlier in life. OBJECTIVES: To test the hypothesis that slow gait speed reflects ...
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Journal ArticleBMC Musculoskelet Disord · May 28, 2019
BACKGROUND: Physical therapy (PT) and other exercise-based interventions are core components of care for knee osteoarthritis (OA), but both are underutilized, and some patients have limited access to PT services. This clinical trial is examining a STepped ...
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Journal ArticleJ Appl Gerontol · March 2019
Objective: The Veterans Health Administration's Care Assessment Need (CAN) score is a statistical model, aimed to predict high-risk patients. We were interested in determining if a relationship existed between physical function and CAN scores. Method: Seve ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · February 15, 2019
Aging is characterized by deleterious immune and metabolic changes, but the onset of these changes is unknown. We measured immune and metabolic biomarkers in adults beginning at age 30. To our knowledge, this is the first study to evaluate these biomarkers ...
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Journal ArticleAIDS Res Hum Retroviruses · November 2018
Antiretroviral therapy (ART) has prolonged lives of persons living with HIV/AIDS (PLWHA), resulting in greater incidence of aging-related diseases and disability. Physical activity (PA) is recommended for healthy aging, but little is known about PA in olde ...
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Journal ArticleFed Pract · November 2018
Clinical video telehealth can be used to deliver functional circuit exercise training to older veterans in remote locations. ...
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Journal ArticleJ Am Geriatr Soc · July 2018
OBJECTIVES: To determine whether combinations of inflammatory markers are related to physical function. DESIGN AND SUBJECTS: secondary analysis of baseline of three observational studies of community-dwelling older adults MEASUREMENTS: The baseline data fr ...
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Journal ArticleAppl Clin Inform · July 2018
OBJECTIVE: Venous thromboembolism (VTE) prophylaxis is an important consideration for hospitalized older adults, and the Padua Prediction Score (PPS) is a risk prediction tool used to prioritize patient selection. We developed an automated PPS (APPS) algor ...
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Journal ArticleJ Am Geriatr Soc · May 2018
Exercise provides a wide range of health-promoting benefits, but support is limited for clinical programs that use exercise as a means of health promotion. This stands in contrast to restorative or rehabilitative exercise, which is considered an essential ...
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ConferenceJournal of Hospital Medicine · April 10, 2018
Background: Clinical practice guidelines state that mobility is supposed to play an important role in determining use and duration of pharmacologic VTE prophylaxis. This study examines whether measured mobility levels relate to pharmacologic VTE prophylaxi ...
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Journal ArticleJ Aging Phys Act · April 1, 2018
This review examined effects of structured exercise (aerobic walking, with or without complementary modes of exercise) on cardiorespiratory measures, mobility, functional status, healthcare utilization, and quality of life in older adults (≥60 years) hospi ...
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Journal ArticleTransl J Am Coll Sports Med · March 15, 2018
Posttraumatic stress disorder (PTSD) affects up to 30% of military veterans. Older veterans, many of whom have lived with PTSD symptoms for several decades, report a number of negative health outcomes. Despite the demonstrated benefits of regular exercise ...
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Journal ArticleGerontol Geriatr Med · 2018
Objective: We used the Physical Performance Across the LifeSpan Study to investigate the relationships of multiple indicators of socioeconomic status (SES), both in early life and late life, with physical function. Method: We examined associations between ...
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Journal ArticleJ Surg (Lisle) · 2018
OBJECTIVES: Impending surgery presents a high risk for older adults given their vulnerability to adverse outcomes. New approaches to peri-operative care bring together surgeons, geriatricians, and other Multidisciplinary specialties to co-manage the geriat ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · April 1, 2017
BACKGROUND: A number of large-scale population studies have provided valuable information about physical performance in aged individuals; however, there is little information about trajectories of function and associations with age across the adult life sp ...
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Journal ArticleJ Am Geriatr Soc · March 2017
OBJECTIVES: To perform an economic evaluation of a primary care-based physical activity counseling intervention that improved physical activity levels and rapid gait speed in older veterans. DESIGN: Secondary objective of randomized trial that assessed the ...
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Journal ArticlePLoS One · 2017
BACKGROUND: As antiretroviral therapy efficacy improves, HIV is gradually being recognized more as a chronic disease within the aging HIV-infected population. While these individuals are surviving into old age, they may, however, be experiencing "accelerat ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · November 2016
BACKGROUND: Older age and obesity are associated with metabolic dysregulation; the mechanism by which these factors impact metabolism across the lifespan is important, but relatively unknown. We evaluated a panel of amino acids (AAs) and acylcarnitines (AC ...
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Journal ArticleJ Geriatr Oncol · November 2016
OBJECTIVES: To characterize factors contributing to physical resilience in older cancer survivors, as demonstrated by resistance to decline or recovery (resilience). MATERIALS AND METHODS: We conducted a secondary analysis of data from a randomized control ...
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Journal ArticleMent Health Phys Act · October 2016
UNLABELLED: Individuals with posttraumatic stress disorder (PTSD) have elevated rates of morbidity, and a sedentary lifestyle can cause and aggravate the physical health needs of adults with PTSD. The primary aim of this paper was to explore the impact of ...
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Journal ArticleJ Am Geriatr Soc · June 2016
OBJECTIVES: To determine the sociodemographic characteristics, health conditions, and cognitive and functional status associated with baseline prevalence and new need for help taking medication 3Â years later and to construct a brief scale indicative of nee ...
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ConferenceJournal of the American Geriatrics Society, Special Issue 2016: Annual Scientific Meeting Abstract Book · April 22, 2016Full textLink to itemCite
Journal ArticleJ Gerontol A Biol Sci Med Sci · April 2016
BACKGROUND: Resilience has been described in the psychosocial literature as the capacity to maintain or regain well-being during or after adversity. Physical resilience is a newer concept that is highly relevant to successful aging. Our objective was to ch ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · March 2016
BACKGROUND: Levels of circulating progenitor cells (CPCs) are depleted with aging and chronic injury and are associated with level of physical functioning; however, little is known about the correlation of CPCs with longer-term measures of physical capabil ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · February 2016
Understanding associations between circulating biomarkers and physical performance across the adult life span could aid in better describing mechanistic pathways leading to disability. We hypothesized that high concentrations of circulating biomarkers woul ...
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Journal ArticleCancer · December 15, 2015
BACKGROUND: The number of older cancer survivors is increasing as more adults survive to older ages. The objectives of this study were to examine trajectories of physical activity (PA) and physical function (PF) over a 2-year lifestyle counseling study and ...
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Journal ArticleJ Geriatr Oncol · November 2015
OBJECTIVES: Many older cancer survivors are overweight or obese, with additional illness burden increasing functional decline, which may affect their ability to engage in lifestyle interventions. This study examined how overweight long-term survivors' symp ...
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Journal ArticleJ Telemed Telecare · April 2015
We determined the effect of a multifaceted stroke telerehabilitation (STeleR) intervention on falls-related self-efficacy and satisfaction with care. We conducted a prospective, randomized, multisite, single-blinded trial in 52 veterans from three Veterans ...
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Journal ArticleCancer Epidemiol Biomarkers Prev · April 2015
Cancer is most often a disease of aging, and frequently, a disease for which obesity serves as a risk factor. Thus, many cancer survivors are older, overweight or obese, with higher illness burden, symptoms, and comorbidities. Against this backdrop, surviv ...
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Journal ArticleHealthy Aging Res · 2015
BACKGROUND: Physical activity interventions typically do not report behavioral changes in activity sub-groups. The aim of this study was to compare baseline differences and changes in physical activity between truly physically inactive men and low active m ...
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Journal ArticleMed Sci Sports Exerc · December 2014
The purposes of this article were to 1) provide an overview of the science of physical activity-related energy expenditure in older adults (≥65 yr), 2) offer suggestions for future research and guidelines for how scientists should be reporting their result ...
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Journal ArticleJ Am Geriatr Soc · November 2014
An important contributor to hospital-associated disability is immobility during hospitalization. Preliminary results from STRIDE, a clinical demonstration program of supervised walking for older adults admitted to the hospital with medical illness, are rep ...
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Journal ArticleAnn Behav Med · October 2014
BACKGROUND: Diet and exercise interventions for cancer survivors result in health benefits; however, few studies have examined health outcomes in relation to adherence. PURPOSE: We examined associations between adherence to components of a diet-exercise in ...
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Journal ArticleMed Sci Sports Exerc · July 2014
UNLABELLED: While moderate- to vigorous-intensity physical activities (MVPA) confer the greatest health benefits, evidence suggests that light-intensity activities are also beneficial, particularly for older adults and individuals with moderate to severe c ...
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Journal ArticleTelemed J E Health · February 2014
BACKGROUND: Hypertension, hyperlipidemia, and diabetes are significant, but often preventable, contributors to cardiovascular disease (CVD) risk. Medication and behavioral nonadherence are significant barriers to successful hypertension, hyperlidemia, and ...
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Journal ArticleBiomed Res Int · 2014
BACKGROUND: Partial unweighted treadmill training is a potentially effective modality for improving fitness and function in frail elders. We tested the feasibility of partial unweighted treadmill training in older, mobility-impaired veterans. METHODS: Eigh ...
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Journal ArticleJ Rehabil Res Dev · 2014
This study examines the effect of posttraumatic stress disorder (PTSD) on function and physical performance in older overweight military Veterans with comorbid conditions. This is a secondary data analysis of older Veterans (mean age = 62.9 yr) participati ...
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Journal Article2014 International Conference on Collaboration Technologies and Systems, CTS 2014 · January 1, 2014
We determined the effect of a multifaceted stroke telerehabilitation (STeleR) intervention on falls-related self-efficacy and satisfaction with care in stroke patients. We conducted a prospective, randomized, multisite, single-blinded trial in 52 veterans ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · December 2013
BACKGROUND: Aging is marked by a decline in physical function. Although the biological underpinnings for this remain unclear, loss of regenerative capacity has been proposed as one cause of the loss of physical function that occurs over time. The quantity ...
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Journal ArticleAm Heart J · April 2013
BACKGROUND: Patients with co-occurrence of hypertension, hyperlipidemia, and diabetes have an increased risk of cardiovascular disease (CVD) events. Comprehensive programs addressing both tailored patient self-management and pharmacotherapy are needed to a ...
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Journal ArticleMed Sci Sports Exerc · March 2013
PURPOSE: This study aimed to measure the metabolic cost (METs) of walking activities in older adults, to examine the relationship between accelerometer output and METs across walking activities, and to compare measured MET values in older adults with the M ...
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Journal ArticleJ Diabetes Complications · 2013
BACKGROUND: One theory of aging and disease development is that chronic injury (pathology) results in activation of regenerative processes and initial repair, with overt disease arising only after exhaustion of reparative capability leads to inadequate rep ...
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Journal ArticleJ Am Geriatr Soc · September 2012
OBJECTIVES: To determine whether a home-based multicomponent physical activity counseling (PAC) intervention is effective in reducing glycemic measures in older outpatients with prediabetes mellitus. DESIGN: Controlled clinical trial. SETTING: Primary care ...
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Journal ArticleStroke · August 2012
BACKGROUND AND PURPOSE: To determine the effect of a multifaceted stroke telerehabilitation (STeleR) intervention on physical function, and secondarily on disability, in veterans poststroke. METHODS: We conducted a prospective, randomized, multisite, singl ...
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Journal ArticleJ Clin Oncol · July 1, 2012
PURPOSE: Diet and exercise interventions have been tested in cancer survivors as a means to reduce late effects and comorbidity, but few have assessed adherence and health outcomes long term. METHODS: Between July 2005 and May 2007, the Reach Out to Enhanc ...
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Journal ArticleJ Acad Nutr Diet · June 2012
BACKGROUND: Older adult cancer survivors are at greater risk of cancer recurrence and other comorbidities that can be prevented through improved diet and weight management. The tertiary prevention needs of rural-dwelling survivors can be even greater, yet ...
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Journal ArticleCrit Care Med · April 2012
BACKGROUND: Millions of patients who survive medical and surgical general intensive care unit care every year experience newly acquired long-term cognitive impairment and profound physical and functional disabilities. To overcome the current reality in whi ...
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Journal ArticleTransl Behav Med · November 2011
Individuals diagnosed with impaired glucose tolerance (i.e., prediabetes) are at increased risk for developing diabetes. We proposed a clinical trial with a novel adaptive randomization designed to examine the impact of a home-based physical activity (PA) ...
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Journal ArticleJ Phys Act Health · September 2011
BACKGROUND: Low physical activity (PA) during the postpartum period is associated with weight retention. While patterns of PA have been examined in normal weight women during this period, little is known about PA among overweight and obese women. The aim o ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · May 2011
BACKGROUND: Metabolic profiling might provide insight into the biologic underpinnings of disability in older adults. METHODS: A targeted mass spectrometry-based platform was used to identify and quantify 45 plasma acylcarnitines in 77 older men with a mean ...
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Journal ArticleJ Aging Res · December 26, 2010
This study assessed the sustained effect of a physical activity (PA) counseling intervention on PA one year after intervention, predictors of sustained PA participation, and three classes of post-intervention PA trajectories (improvers, maintainers, and de ...
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Journal Article · December 1, 2010
There is abundant evidence supporting the health benefits of physical activity, including reduced risk for cardiovascular disease, stroke, some cancers, type 2 diabetes, osteoporosis, hypertension, high cholesterol, obesity, osteoarthritis, and all-cause m ...
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Journal ArticleJ Aging Phys Act · October 2010
The purpose of this study was to examine what happens to goals over the course of a physical activity counseling trial in older veterans. At baseline, participants (N = 313) identified 1 health-related goal and 1 walking goal for their participation in the ...
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Journal ArticleMetab Syndr Relat Disord · August 2010
BACKGROUND: The specific health benefits of meeting physical activity guidelines are unclear in older adults. We examined the association between meeting, not meeting, or change in status of meeting physical activity guidelines through walking and the 5-ye ...
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Journal ArticleTrials · June 30, 2010
BACKGROUND: Stroke is one of the most disabling and costly impairments of adulthood in the United States. Stroke patients clearly benefit from intensive inpatient care, but due to the high cost, there is considerable interest in implementing interventions ...
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Journal ArticleAnn Behav Med · June 2010
BACKGROUND: Few studies have examined the associations between exercise self-efficacy, goals, and physical activity over time. PURPOSE: This study examines whether self-selected goals mediate the changes in exercise self-efficacy on physical activity over ...
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Journal ArticleScand J Rheumatol · May 2010
OBJECTIVES: Physical activity (PA) has the potential to improve outcomes in both arthritis and diabetes, but these conditions are rarely examined together. Our objective was to explore whether persons with arthritis alone or those with both arthritis and d ...
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Journal ArticleScand J Rheumatol · 2010
OBJECTIVES: The primary aim was to explore whether arthritis is associated with poorer self-efficacy and motivation for, and participation in, two specific types of physical activity (PA): endurance training (ET) and strength training (ST). A further objec ...
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Journal ArticleJ Am Geriatr Soc · November 2009
Currently, there are about 7 million cancer survivors in this country aged 65 and older, and this number is expected to increase rapidly, given trends toward aging and improvements in early detection and treatment. Unfortunately, cancer survivors are at ri ...
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Journal ArticleAm J Prev Med · September 2009
BACKGROUND: Pregnancy may contribute to overweight and obesity. PURPOSE: The primary objective of Active Mothers Postpartum was to promote a reduction in BMI through 24-months postpartum via sustainable lifestyle changes. DESIGN: Behavioral intervention RC ...
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Journal ArticleCancer · September 1, 2009
BACKGROUND: Older cancer survivors are at increased risk for secondary cancers, cardiovascular disease, obesity, and functional decline and, thus, may benefit from health-related interventions. However, to the authors' knowledge, little is known regarding ...
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Journal ArticleJ Am Geriatr Soc · July 2009
OBJECTIVES: To determine the effects of primary care-based, multicomponent physical activity counseling (PAC) promoting physical activity (PA) guidelines on gait speed and related measures of PA and function in older veterans. DESIGN: Randomized controlled ...
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Journal ArticleJ Gerontol B Psychol Sci Soc Sci · June 2009
We examined associations between positive emotion (PE) and functional status (Duke Activity Status Inventory) in 948 coronary artery disease (CAD) patients (35.1% women; age M = 70.1 years, SD = 6.3). Emotion and function measures were gathered during hosp ...
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Journal ArticleJAMA · May 13, 2009
CONTEXT: Five-year survival rates for early stage colorectal, breast, and prostate cancer currently exceed 90% and are increasing. Cancer survivors are at greater risk for second malignancies, other comorbidities, and accelerated functional decline. Lifest ...
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Journal ArticleJ Clin Endocrinol Metab · April 2009
CONTEXT: GH secretion declines with age, possibly contributing to reduced muscle mass, strength, and function. GH secretagogues (GHS) may increase muscle mass and physical performance. OBJECTIVES/DESIGN: We conducted a randomized, double-masked, placebo-co ...
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Journal ArticlePsychooncology · April 2009
OBJECTIVE: Cure rates for cancer are increasing, especially for breast, prostate, and colorectal cancer. Despite positive trends in survivorship, a cancer diagnosis can trigger accelerated functional decline that can threaten independence, reduce quality-o ...
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Journal ArticleJ Am Geriatr Soc · April 2009
OBJECTIVES: To describe the relationship between symptom scores and mobility function measures, assess whether symptom scores and disease scores are similarly associated with mobility function, and identify clusters of symptoms that are most strongly assoc ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · January 2009
BACKGROUND: It is unclear if physical activity (PA) can prevent or reverse frailty. We examined different doses and types of PA and their association with the onset and severity of frailty. METHODS: Health, Aging and Body Composition (Health ABC) study par ...
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Journal ArticleJ Womens Health (Larchmt) · December 2008
BACKGROUND: Pregnancy and the postpartum period have been suggested as important contributors to overweight and obesity among women. This paper presents the design, rationale, and baseline participant characteristics of a randomized controlled intervention ...
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Journal ArticleJ Am Geriatr Soc · October 2008
OBJECTIVES: To determine whether elderly people who meet national guidelines have higher physical function (PF) scores than those who do not and the effect on functional trajectory when physical activity (PA) levels change from above to below this threshol ...
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Journal ArticleJ Cancer Surviv · September 2008
INTRODUCTION: The purpose of the present study was to assess dietary supplement use and its association with micronutrient intakes and diet quality among older (>or=65 years), long-term survivors (>or=5 years post-diagnosis) of female breast, prostate, and ...
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Journal ArticleArch Intern Med · May 12, 2008
BACKGROUND: We evaluated the effects of counseling linked with primary care visits on walking and "strength exercise" (the combination of strength-building and flexibility exercise) in aging veterans. METHODS: Male veterans aged 60 to 85 years (N = 224) wi ...
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Journal ArticleJ Rehabil Res Dev · 2008
Insufficient levels of physical activity have significant clinical consequences. Primary care settings typically do not emphasize physical activity counseling. We describe the design, methods, and baseline characteristics of "Learning to Improve Fitness an ...
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Journal ArticleAm J Mens Health · December 2007
This study sought to determine if telephone exercise counseling attenuates frailty in older, male veterans through increased levels of physical activity. Eighty-one elderly, male veterans (age = 78.4 +/- 4.9 years) randomized to intervention (n = 39) or co ...
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Journal ArticleJ Am Diet Assoc · September 2007
OBJECTIVE: To utilize the Diet Quality Index-Revised (DQI-R) as a framework for delivering and evaluating an intervention to improve overall diet quality among older cancer survivors. DESIGN: As part of a randomized controlled trial to improve lifestyle be ...
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Journal ArticleJ Am Geriatr Soc · January 2007
OBJECTIVES: To explore the potential of using step activity monitoring to detect differences in ambulatory activity associated with advancing age and declining function in community-dwelling seniors. DESIGN: Cross-sectional pilot study. SETTING: General co ...
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Journal ArticleJ Clin Oncol · July 20, 2006
PURPOSE: Declines in physical functioning (PF) among elderly cancer patients threaten quality of life and the ability to maintain independence. Adherence to healthy lifestyle behaviors may prevent functional decline. PATIENTS AND METHODS: Project Leading t ...
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Journal ArticleJ Aging Phys Act · July 2006
The authors describe a medical center-based randomized trial aimed at determining the feasibility and effectiveness of partnering patients and primary-care providers with an exercise health counselor. Study participants included 165 veterans age 70 years a ...
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Journal ArticleObes Res · October 2005
OBJECTIVE: To examine associations of weight history with functional limitations and disability in white and African-American men and women. RESEARCH METHODS AND PROCEDURES: Data were from the Atherosclerosis Risk in Communities study (n = 11,177). Associa ...
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Journal ArticleJ Clin Oncol · June 2005
8138 Background: Declines in physical function occur with cancer, and threaten ability to maintain independence. Functional decline is a serious problem among older cancer survivors, since functional status already may be compromised. Adherence to healthy ...
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Journal ArticleJ Rehabil Res Dev · 2005
This study evaluated the use of walking speed as an indicator of function and health status in acutely ill, hospitalized, older male veterans. Hospital inpatients in a Department of Veterans Affairs (VA) study of Geriatric Evaluation and Management (GEM) ( ...
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Journal ArticleInt J Behav Nutr Phys Act · October 29, 2004
BACKGROUND: Functional decline threatens independent living and is common among individuals diagnosed with cancer, especially those who are elderly. The purpose of this study was to explore whether dietary and exercise practices are associated with physica ...
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Journal ArticleJ Rehabil Res Dev · September 2004
We examined the associations between sedentary older veterans, those regularly involved in an outpatient exercise program and physical function. Sedentary and currently exercising older veterans performed a 30 s chair-stand test and 6 min walk test as part ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · December 2003
BACKGROUND: Current theory about how an older adult's leg strength influences walking speed is based primarily on nonlinear patterns of association observed in cross-sectional data. Compared with adults with normal or high levels of leg muscle strength, we ...
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Journal ArticleAm J Prev Med · October 2003
The universal caution to consult your family doctor before beginning an exercise program creates an image of exercise as potentially harmful. Moreover, insistence on extensive screening prior to exercise is both unrealistic and often inappropriate for the ...
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Journal ArticleJ Womens Health (Larchmt) · May 2003
PURPOSE: Functional differences between the sexes are well documented. The causes of functional decline are complex, but in general, women report more functional decline and have a greater prevalence of disabling chronic conditions than do men. The role of ...
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Journal ArticleMil Med · April 2003
Overweight and obesity among soldiers and their dependents have increased over the last decade, mirroring rates in the general population. In general, few programs that result in sustained weight loss have been evaluated, although effective interventions c ...
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Journal ArticleControl Clin Trials · April 2003
The U.S. population is aging, bringing with it an increased prevalence of chronic disease and concomitant declines in physical function. The risk of developing cancer increases significantly with age, and functional decline is much more likely once a cance ...
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Journal ArticleMed Sci Sports Exerc · January 2003
PURPOSE: We explored the accuracy and bias of prediction equations (ACSM and Foster) in older, deconditioned men and women. We also examined the predictors of VO2(max) to further understand which variables affect respiratory fitness in the elderly. METHODS ...
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Journal ArticleJournal of Aging and Physical Activity · January 1, 2003
Getting older adults to initiate and maintain long-term exercise is an important public health mandate. This study is an analysis of a clinical trial of 112 sedentary adults, age 65-90 years, randomly assigned to 1 of 2 exercise interventions. We examined ...
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Journal ArticleJ Am Geriatr Soc · December 2002
OBJECTIVES: To compare mortality of adherents and nonadherents of an exercise program. DESIGN: Prospective intervention study. SETTING: Supervised geriatric fitness program called Gerofit. PARTICIPANTS: One hundred thirty-five adults aged 65 and older who ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · August 2000
BACKGROUND: One area of research that requires further elaboration is the relationship between impairments and functional limitations. By identifying specific contributors to functional limitations, it may be possible to establish intervention strategies, ...
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Journal ArticleCirculation · September 7, 1999
BACKGROUND: The age-related decline in maximal oxygen consumption is attenuated by habitual aerobic exercise. However, the relative effects of training on central and peripheral responses to exercise in older subjects are not known. The present study asses ...
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Journal ArticleJ Gerontol A Biol Sci Med Sci · July 1999
BACKGROUND: As exercise is associated with favorable health outcomes, impaired older adults may benefit from specialized exercise interventions to achieve gains in function. The purpose of this study was to determine the added benefit of a spinal flexibili ...
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Journal ArticleArch Phys Med Rehabil · May 1999
OBJECTIVES: (1) To assess the test-retest reliability of physical performance tests in subject groups with different levels of impairment and disability, and (2) to assess the stability of these tests over different time intervals. DESIGN: Test-retest, rep ...
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Journal ArticleMed Sci Sports Exerc · August 1998
PURPOSE: Few studies have examined the relationship between directly measured oxygen uptake (VO2) and self-reported physical function (PF). The purpose of this study was: 1) to examine the relationship between peak V02 and PF and 2) to determine whether a ...
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Journal ArticleMed Sci Sports Exerc · May 1998
BACKGROUND: Conceptual models of disability have focused on disease-specific factors as the primary cause of disability. Functional limitations in the performance of basic tasks are considered primary mediators on the causal pathway from disease to disabil ...
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Journal ArticleJ Am Geriatr Soc · October 1996
OBJECTIVE: To examine 5-year trends in measures of physical performance, and the impact of disease upon performance, in three domains: cardiovascular fitness, musculo-skeletal strength, and flexibility among older adults participating in a medically superv ...
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Journal ArticleSouth Med J · May 1994
In 1986 Gerofit, an exercise and health promotion program for older veterans, was established. This paper describes the program in detail by summarizing the patient assessment protocol, the exercise program, and program evaluation, as well as observational ...
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Journal ArticleSleep · June 1993
In the current study 12 aerobically fit and 12 sedentary older men underwent two nocturnal polysomnographic (PSG) studies. A control PSG was conducted following a day without aerobic activity, whereas a postexercise PSG study was conducted following an aft ...
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Journal ArticleJ Appl Gerontol · December 1991
This study examined the impact of supervised exercise on the health status (measured by the Sickness Impact Profile [SIP]) and well-being (measured by the Psychological General Well-Being Index [PGWB]) of a sample of 43 elderly veterans. The intervention c ...
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Journal ArticleJ Am Geriatr Soc · October 1991
The extent to which exercise can delay the normal decline in physical performance associated with aging is unknown. We examined the impact of 2 years of supervised exercise on cardiovascular fitness, flexibility, and strength in a group of elderly (age 65- ...
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Journal ArticleJ Am Geriatr Soc · June 1991
The extent to which exercise can delay the normal decline in physical performance associated with aging is unknown. We examined the impact of 2 years of supervised exercise on cardiovascular fitness, flexibility, and strength in a group of elderly (age 65- ...
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Journal ArticleJ Am Geriatr Soc · April 1989
Most studies that assess the effects of exercise in the elderly involve subjects who are in good health. The objective of this prospective longitudinal study was to examine the impact of exercise on cardiovascular fitness, flexibility, and strength in an e ...
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Journal ArticleJ Med Chem · April 1988
A number of 1,2,4-trioxanes were prepared and tested for antimalarial activity in search of a simplified analogue of the naturally occurring antimalarial qinghaosu. The compounds were assayed in an in vitro system for antimalarial activity against chloroqu ...
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Journal ArticleHypertension · 1985
To test the hypothesis that environmental as well as genetic factors are important determinants of monovalent cation transport systems in humans, and to explore potential basic mechanisms of the alleged antihypertensive effects of habitual exercise, we stu ...
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Journal ArticleJ Mol Cell Cardiol · May 1984
To test the hypothesis that alterations in adrenergic or cholinergic receptors occur in response to physical training, and that changes in receptor properties could be mechanistically important in producting the altered cardiovascular physiology of the tra ...
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Journal ArticlePostgrad Med · July 1981
While the incidence of major medical emergencies during competitive distance running is low, the large and growing number of persons involved, including the elderly, mandates serious attention by the medical community to provision of adequate prevention an ...
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