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Shenglan Tang

Mary D.B.T. and James H. Semans International Distinguished Professor
Population Health Sciences

Selected Publications


Pandemic preparedness in Vietnam: a review of health system resilience and areas for improvement.

Journal Article J Glob Health · January 24, 2025 In this viewpoint, we explore Vietnam's health system vulnerabilities and its national response to the COVID-19 pandemic, as well as critical areas of health system resilience, including health financing, workforce distribution, information systems, and go ... Full text Link to item Cite

Zero-Dose Vaccination of Self-Paid Vaccines Among Migrant and Left-Behind Children in China: Evidence from Zhejiang and Henan Provinces.

Journal Article Vaccines (Basel) · January 24, 2025 BACKGROUND/OBJECTIVES: As zero-dose vaccination has become a global health concern, understanding the practice of self-paid immunizations in migrant and left-behind children in China is crucial to the prevention and control of infectious diseases. METHODS: ... Full text Link to item Cite

Primary Care-Based Digital Health-Enabled Stroke Management Intervention: Long-Term Follow-Up of a Cluster Randomized Clinical Trial.

Journal Article JAMA Netw Open · December 2, 2024 IMPORTANCE: Despite evidence of the short-term benefits of multicomponent primary care-based interventions, their long-term effects are unproven. OBJECTIVE: To evaluate the long-term outcomes of a system-integrated technology-enabled model of care (SINEMA ... Full text Link to item Cite

The Effect of Interventions Based on the Information-Motivation-Behavioral Skills Model on the Human Papillomavirus Vaccination Rate Among 11-13-Year-Old Girls in Central and Western China: Protocol for a Randomized Controlled Trial.

Journal Article JMIR Res Protoc · November 19, 2024 BACKGROUND: Persistent infection of high-risk human papillomavirus (HPV) can lead to cervical intraepithelial neoplasia, cervical cancer, and even death. HPV vaccination for girls aged 9-14 years can effectively prevent the occurrence of cervical cancer. S ... Full text Link to item Cite

Patient delay, diagnosis delay, and treatment outcomes among migrant patients with tuberculosis in Shanghai, China, 2018-2020: a mixed-methods study.

Journal Article BMJ Open · October 26, 2024 OBJECTIVES: This study aimed to examine patient delay, diagnosis delay and treatment performance among patients with tuberculosis (TB) in Shanghai, China in 2018-2020 focusing on disparities between migrant and local patients with TB. DESIGN: Mixed-method ... Full text Link to item Cite

COVID-19 Vaccine Hesitancy Among People Living with HIV: A Systematic Review and Meta-Analysis.

Journal Article AIDS Behav · July 2024 Vaccine hesitancy is one of the top 10 threats to global health, which affects the prevalence and fatality of vaccine-preventable diseases over the world. During the COVID-19 pandemic, people living with HIV (PLWH) may have higher risks of infection, more ... Full text Link to item Cite

Hospital response to a new case-based payment system in China: the patient selection effect.

Journal Article Health Policy Plan · May 15, 2024 Providers have intended and unintended responses to payment reforms, such as China's new case-based payment system, i.e. Diagnosis-Intervention Packet (DIP) under global budget, that classified patients based on the combination of principal diagnosis and p ... Full text Open Access Link to item Cite

Policy gaps in addressing market failures and intervention misalignments in tuberculosis control: prospects for improvement in China, India, and Indonesia.

Journal Article Lancet Reg Health West Pac · May 2024 India, Indonesia, and China are the top three countries with the highest tuberculosis (TB) burden. To achieve the end TB target, we analyzed policy gaps in addressing market failures as well as misalignments between National TB Programs (NTP) and health in ... Full text Link to item Cite

Government responses to the COVID-19 pandemic of the Gulf Cooperation Council countries: good practices and lessons for future preparedness.

Journal Article Glob Health Res Policy · March 15, 2024 The COVID-19 pandemic has dramatically threatened the Gulf Cooperation Council (GCC) countries which have a large proportion of foreign workers. The governments of GCC countries have proactively implemented a comprehensive set of policy measures, and up to ... Full text Link to item Cite

Advancing the National Immunization Program in an era of achieving universal vaccine coverage in China and beyond.

Journal Article Infect Dis Poverty · March 13, 2024 BACKGROUND: Immunization is a cornerstone of public health. Despite great success, China's National Immunization Program (NIP) faces challenges, such as the integration of several World Health Organization-recommended vaccines and other systemic issues. Th ... Full text Link to item Cite

Rapid growth of private hospitals in China: emerging challenges and opportunities to health sector management.

Journal Article Lancet Reg Health West Pac · March 2024 China's private hospital market has experienced rapid growth over the last decade, with private hospitals now outnumbering public hospitals by a factor of two. This policy analysis uses available data and existing literature to analyze China's rapidly chan ... Full text Link to item Cite

Promoting higher-valent pediatric combination vaccines in China: challenges and recommendations for action.

Journal Article Infect Dis Poverty · February 1, 2024 Many countries have adopted higher-valent pediatric combination vaccines to simplify vaccination schedules and minimize health expenditures and social costs. However, China is conservative in the use of pediatric combination vaccines. By reviewing and synt ... Full text Link to item Cite

Between now and later: a mixed methods study of HPV vaccination delay among Chinese caregivers in urban Chengdu, China.

Journal Article BMC Public Health · January 15, 2024 BACKGROUND: Adolescent girls in China have a low HPV vaccination rate. Although vaccination is recommended by the Chinese health authorities, the cost is not covered by the national immunisation programme. Vaccination delay, among other reasons such as sup ... Full text Link to item Cite

Differential effect of China's Zero Markup Drug Policy on provider-induced demand in secondary and tertiary hospitals.

Journal Article Front Public Health · 2024 Following the marketization of China's health system in the 1980's, the government allowed public hospitals to markup the price of certain medications by 15% to compensate for reduced revenue from government subsidies. This incentivized clinicians to induc ... Full text Link to item Cite

The Impact of a New Case-Based Payment System on Quality of Care: A Difference-in-Differences Analysis in China.

Journal Article Risk Manag Healthc Policy · 2024 PURPOSE: China has developed and widely piloted a new case-based payment, ie, the "Diagnosis-Intervention Packet" (DIP) payment, which has a granular classification system. We evaluated the impact of DIP payment on the quality of care in a large pilot city ... Full text Link to item Cite

The coverage and challenges of increasing uptake of non-National Immunization Program vaccines in China: a scoping review.

Journal Article Infect Dis Poverty · December 8, 2023 BACKGROUND: Non-National Immunization Program (NIP) vaccines have played an important role in controlling vaccine-preventable diseases (VPDs) in China. However, these vaccines are paid out of pocket and there is room to increase their coverage. We focused ... Full text Link to item Cite

ChatGPT: promise and challenges for deployment in low- and middle-income countries.

Journal Article Lancet Reg Health West Pac · December 2023 In low- and middle-income countries (LMICs), the fields of medicine and public health grapple with numerous challenges that continue to hinder patients' access to healthcare services. ChatGPT, a publicly accessible chatbot, has emerged as a potential tool ... Full text Link to item Cite

Cost Drivers and Financial Burden for Cancer-Affected Families in China: A Systematic Review.

Journal Article Curr Oncol · August 16, 2023 This systematic review examined cancer care costs, the financial burden for patients, and their economic coping strategies in mainland China. We included 38 quantitative studies that reported out-of-pocket payment for cancer care and patients' coping strat ... Full text Link to item Cite

Addressing cancer care in low- to middle-income countries: a call for sustainable innovations and impactful research.

Journal Article BMC Cancer · August 15, 2023 Most new cancer cases are currently arising in low- and middle-income countries, where their outcomes are significantly poorer compared to high-income countries. Innovative solutions are imperiously needed to prevent, detect early, and manage cancer in low ... Full text Link to item Cite

Pay-it-forward to increase uptake among 15-18-year-old adolescent girls compared with user-paid vaccination: The pilot results of a two-arm randomized controlled trial in China.

Journal Article Res Sq · May 25, 2023 BACKGROUND: China has low human papillomavirus(HPV) vaccination rate due to lack of public funding and mistrust in domestic vaccines. This pilot study evaluated the feasibility and preliminary effectiveness of an innovative pay-it-forward strategy, which h ... Full text Link to item Cite

Trends in global health research among universities in China: a bibliometric analysis.

Journal Article Glob Health Res Policy · April 6, 2023 BACKGROUND: There has been considerable progress in developing global health education and research in China. Nevertheless, evidence of the progress of Chinese universities' contributions to global health research is limited. More efforts are needed to dep ... Full text Link to item Cite

Delays in cancer care for children in low-income and middle-income countries: development of a composite vulnerability index.

Journal Article Lancet Glob Health · April 2023 BACKGROUND: Early access to diagnosis and care is essential to improve rates of survival from childhood cancer, particularly in low-income and middle-income countries (LMICs). Composite indices are increasingly used to compare country performance in many h ... Full text Link to item Cite

Determinants of delayed childhood cancer care in low- and middle-income countries: A systematic review.

Journal Article Pediatr Blood Cancer · March 2023 Early access to care is essential to improve survival rates for childhood cancer. This study evaluates the determinants of delays in childhood cancer care in low- and middle-income countries (LMICs) through a systematic review of the literature. We propose ... Full text Link to item Cite

The effectiveness of pay-it-forward in addressing HPV vaccine delay and increasing uptake among 15-18-year-old adolescent girls compared to user-paid vaccination: a study protocol for a two-arm randomized controlled trial in China.

Journal Article BMC Public Health · January 7, 2023 BACKGROUND: Human papillomavirus (HPV) vaccination could prevent cervical and other HPV-associated cancers attributable to vaccine-associated HPV types. However, HPV vaccination coverage among women aged 9-18 years old is low in China. Common barriers incl ... Full text Link to item Cite

Developing an effective and sustainable national immunisation programme in China: issues and challenges.

Journal Article Lancet Public Health · December 2022 Since its establishment in 1978, China's National Immunization Program has made remarkable achievements in the control of vaccine-preventable diseases. The National Immunization Program is a vertically integrated programme in the health system, which deliv ... Full text Link to item Cite

Disease burden of ageing, sex and regional disparities and health resources allocation: a longitudinal analysis of 31 provinces in Mainland China.

Journal Article BMJ Open · November 16, 2022 OBJECTIVES: To measure the disease burden of ageing based on age-related diseases (ARDs), the sex and regional disparities and the impact of health resources allocation on the burden in China. DESIGN: A national comparative study based on Global Burden of ... Full text Link to item Cite

Impact of the national hepatitis B immunization program in China: a modeling study.

Journal Article Infect Dis Poverty · October 11, 2022 BACKGROUND: Elimination of hepatitis B virus (HBV) is a striking challenge for countries with high or moderate disease burden. Therefore, using China as a practical case to share experiences for similar countries may accelerate the achievement of the WHO 2 ... Full text Link to item Cite

The co-management of tuberculosis-diabetes co-morbidities in Indonesia under the National Tuberculosis Control Program: results from a cross-sectional study from 2017 to 2019.

Journal Article BMC Public Health · April 8, 2022 BACKGROUND: Indonesia suffers from a high burden of tuberculosis (TB) and diabetes (DM). The government initiated national TB-DM co-management activities under the National TB Control Program in 2017. This study investigates the detection and treatment out ... Full text Link to item Cite

Health Services Use and Expenditures among Middle-Aged and Elderly Residents with Hypertension Comorbidity: A Longitudinal Study in Jiangsu Province, China

Journal Article Chinese Economy · January 1, 2022 Hypertension is the most prevalent chronic condition in China and is associated with an increased risk of comorbidity. This study aims to investigate health services use and expenditures among community-dwelling residents with hypertension comorbidity. Dat ... Full text Cite

Chronic kidney disease biomarkers and mortality among older adults: A comparison study of survey samples in China and the United States.

Journal Article PLoS One · 2022 OBJECTIVES: Among older adults in China and the US, we aimed to compare the biomarkers of chronic-kidney-diseases (CKD), factors associated with CKD, and the correlation between CKD and mortality. SETTING: China and the US. STUDY DESIGN: Cross-sectional an ... Full text Link to item Cite

A Southeast Asian collaborative Delphi consensus on surveying risk factors for head and neck cancer screening and prevention.

Journal Article Glob Surg · 2022 The objective of this study was to determine high value questions for early detection and prevention of head and neck cancer by querying content experts on patient risk factors relevant to local communities in Southeast Asia (i.e., Vietnam, Laos, China, an ... Open Access Link to item Cite

Ending tuberculosis in China: health system challenges.

Journal Article Lancet Public Health · December 2021 China has made remarkable progress in reducing tuberculosis cases and deaths during the past three decades; however, it is still far from achieving the targets set out in the WHO End TB Strategy. Since the 2000s, China has tried to transform its vertical t ... Full text Link to item Cite

Effective COVID-19 Control: A Comparative Analysis of the Stringency and Timeliness of Government Responses in Asia.

Journal Article Int J Environ Res Public Health · August 17, 2021 AIM: Many governments in East and Southeast Asia responded promptly and effectively at the onset of the COVID-19 pandemic. Synthesizing and analyzing these responses is vital for disease control evidence-based policymaking. METHODS: An extensive review of ... Full text Link to item Cite

Melatonin regulates antioxidant strategy in response to continuous salt stress in rice seedlings.

Journal Article Plant Physiol Biochem · August 2021 Melatonin mediates multiple physiological processes in plants and is involved in many reactions related to the protection of plants from abiotic stress. In this paper, the effect of melatonin on the antioxidant capacity of rice under salt stress was studie ... Full text Link to item Cite

Access to quality diagnosis and rational treatment for tuberculosis: real-world evidence from China-Gates Tuberculosis Control Project Phase III.

Journal Article Infect Dis Poverty · June 29, 2021 BACKGROUND: China has successfully reduced tuberculosis (TB) incidence rate over the past three decades, however, challenges remain in improving the quality of TB diagnosis and treatment. In this paper, we assess the effects of the implementation of "China ... Full text Link to item Cite

Impact of immunization programs on 11 childhood vaccine-preventable diseases in China: 1950-2018.

Journal Article Innovation (Camb) · May 28, 2021 To evaluate the achievements of China's immunization program between 1950 and 2018, we chose 11 vaccine-preventable diseases (VPDs) as representative notifiable diseases and used annual surveillance data obtained between 1950 and 2018 to derive disease inc ... Full text Link to item Cite

The effectiveness of E-learning in continuing medical education for tuberculosis health workers: a quasi-experiment from China.

Journal Article Infect Dis Poverty · May 18, 2021 BACKGROUND: Given the context of rapid technological change and COIVD-19 pandemics, E-learning may provide a unique opportunity for addressing the challenges in traditional face-to-face continuing medical education (CME). However, the effectiveness of E-le ... Full text Link to item Cite

Impacts of a comprehensive tuberculosis control model on the quality of clinical services and the financial burden of treatment for patients with drug-resistant tuberculosis in China: a mixed-methods evaluation.

Journal Article Infect Dis Poverty · April 21, 2021 BACKGROUND: The China National Health Commission-Gates TB Project Phase III implemented a comprehensive TB control model including multiple interventions to address the burden of drug-resistant TB (DRTB). This study aims to evaluate the quality of DRTB cli ... Full text Link to item Cite

Policy changes and the screening, diagnosis and treatment of drug-resistant tuberculosis patients from 2015 to 2018 in Zhejiang Province, China: a retrospective cohort study.

Journal Article BMJ Open · April 12, 2021 OBJECTIVES: To examine changes in the screening, diagnosis, treatment and management of drug-resistant tuberculosis (DRTB) patients, and investigate the impacts of DRTB-related policies on patients of different demographic and socioeconomic characteristics ... Full text Link to item Cite

Ten-year impacts of China's rural health scheme: lessons for universal health coverage.

Journal Article BMJ Glob Health · April 2021 China has made profound progress in advancing universal health coverage (UHC) over the past two decades. New Cooperative Medical Scheme (NCMS) was initiated in 2003 to provide health insurance coverage to rural population. Its benefit packages and cost-sha ... Full text Link to item Cite

Effectiveness of a primary care-based integrated mobile health intervention for stroke management in rural China (SINEMA): A cluster-randomized controlled trial.

Journal Article PLoS Med · April 2021 BACKGROUND: Managing noncommunicable diseases through primary healthcare has been identified as the key strategy to achieve universal health coverage but is challenging in most low- and middle-income countries. Stroke is the leading cause of death and disa ... Full text Link to item Cite

Implementing a new tuberculosis surveillance system in Zhejiang, Jilin and Ningxia: improvements, challenges and implications for China's National Health Information System.

Journal Article Infect Dis Poverty · March 10, 2021 BACKGROUND: China is still faced with the public health challenge of tuberculosis (TB), and a robust surveillance system is critical for developing evidence-based TB control policies. The Tuberculosis Information Management System (TBIMS), an independent s ... Full text Link to item Cite

Process evaluation of E-learning in continuing medical education: evidence from the China-Gates Foundation Tuberculosis Control Program.

Journal Article Infect Dis Poverty · March 10, 2021 BACKGROUND: E-learning is a growing phenomenon which provides a unique opportunity to address the challenges in continuing medical education (CME). The China-Gates Foundation Tuberculosis (TB) Control Program implemented online training for TB health worke ... Full text Link to item Cite

Multi-source financing for tuberculosis treatment in China: key issues and challenges.

Journal Article Infect Dis Poverty · March 10, 2021 BACKGROUND: The End Tuberculosis (TB) Strategy of the World Health Organization highlights the need for patient-centered care and social protection measures that alleviate the financial hardships faced by many TB patients. In China, TB treatments are paid ... Full text Link to item Cite

Elements and Performance Indicators of Integrated Healthcare Programmes on Chronic Diseases in Six Countries in the Asia-Pacific Region: A Scoping Review.

Journal Article Int J Integr Care · February 8, 2021 BACKGROUND AND AIMS: Globally, hospital-based healthcare models targeting acute care, are not effective in addressing chronic conditions. Integrated care programmes for chronic diseases have been widely developed and implemented in Europe and North America ... Full text Link to item Cite

Impact of multiple policy interventions on the screening and diagnosis of drug-resistant tuberculosis patients: a cascade analysis on six prefectures in China.

Journal Article Infect Dis Poverty · January 19, 2021 BACKGROUND: The detection of drug-resistant tuberculosis (DR-TB) is a major health concern in China. We aim to summarize interventions related to the screening and detection of DR-TB in Jiangsu Province, analyse their impact, and highlight policy implicati ... Full text Link to item Cite

Socio-Economic and Rural-Urban Differences in Healthcare and Catastrophic Health Expenditure Among Cancer Patients in China: Analysis of the China Health and Retirement Longitudinal Study.

Journal Article Front Public Health · 2021 Objective: In China, cancer accounts for one-fifth of all deaths, and exerts a heavy toll on patients, families, healthcare systems, and society as a whole. This study aims to examine the temporal trends in socio-economic and rural-urban differences in tre ... Full text Link to item Cite

Adherence to Multidrug Resistant Tuberculosis Treatment and Case Management in Chongqing, China - A Mixed Method Research Study.

Journal Article Infect Drug Resist · 2021 AIM: This paper evaluated the treatment adherence for multidrug-resistant tuberculosis (MDR-TB) and MDR-TB case management (MTCM) in Chongqing, China in order to identify factors associated with poor treatment adherence and case management. METHODS: Survey ... Full text Link to item Cite

Improving maternal and child nutrition in China: an analysis of nutrition policies and programs initiated during the 2000-2015 Millennium Development Goals era and implications for achieving the Sustainable Development Goals.

Journal Article J Health Popul Nutr · December 2, 2020 BACKGROUND: Although good progress was made in maternal and child nutrition during the Millennium Development Goals (MDGs) era, malnutrition remains one of the major threats on global health. Therefore, the United Nation set several nutrition-related goals ... Full text Link to item Cite

Advancing universal health coverage in China and Vietnam: lessons for other countries.

Journal Article BMC Public Health · November 25, 2020 BACKGROUND: China and Vietnam have made impressive progress towards universal health coverage (UHC) through government-led health insurance reforms. We compared the different pathways used to achieve UHC, to identify the lessons other countries can learn f ... Full text Link to item Cite

How and to what extent can pensions facilitate increased use of health services by older people: evidence from social pension expansion in rural China.

Journal Article BMC Health Serv Res · November 4, 2020 BACKGROUND: The proportion of people aged 60 years or over is growing faster than other age groups. Traditionally, retirement has been considered as both a loss to the labour market and an additional economic burden on the nation. More recently, it is wide ... Full text Open Access Link to item Cite

Reduction in healthcare services during the COVID-19 pandemic in China.

Journal Article BMJ Glob Health · November 2020 INTRODUCTION: The COVID-19 pandemic caused a healthcare crisis in China and continues to wreak havoc across the world. This paper evaluated COVID-19's impact on national and regional healthcare service utilisation and expenditure in China. METHODS: Using a ... Full text Link to item Cite

Does health insurance impact health service utilization among older adults in urban China? A nationwide cross-sectional study.

Journal Article BMC Health Serv Res · July 9, 2020 BACKGROUND: China's rapidly aging population has led to many challenges related to the health care delivery and financing. Since 2007, the Urban Residents Basic Medical Insurance (URBMI) program has provided financial protection for older adults living in ... Full text Link to item Cite

Effective coverage for hypertension treatment among middle-aged adults and the older population in China, 2011 to 2013: A nationwide longitudinal study.

Journal Article J Glob Health · June 2020 METHODS: We used the baseline survey and first follow-up surveys of the China Health and Retirement Longitudinal Study of middle-aged and older populations conducted between 2011 and 2013. Correlates of effective coverage and treatment coverage for hyperte ... Full text Link to item Cite

Physical multimorbidity, health service use, and catastrophic health expenditure by socioeconomic groups in China: an analysis of population-based panel data.

Journal Article Lancet Glob Health · June 2020 BACKGROUND: Multimorbidity, the presence of two or more mental or physical chronic non-communicable diseases, is a major challenge for the health system in China, which faces unprecedented ageing of its population. Here we examined the distribution of phys ... Full text Link to item Cite

Achieving SDG related sexual and reproductive health targets in China: what are appropriate indicators and how we interpret them?

Journal Article Reprod Health · June 1, 2020 BACKGROUND: Sexual and Reproductive Health (SRH) targets have been included as part of the United Nations Sustainable Development Goals and indictors are important to monitor progress towards these targets. SRH indicators are recommended for setting norms ... Full text Link to item Cite

Combating hepatitis B and C by 2030: achievements, gaps, and options for actions in China.

Journal Article BMJ Glob Health · June 2020 China has the highest number of hepatitis B and C cases globally. Despite remarkable achievements, China faces daunting challenges in achieving international targets for hepatitis elimination. As part of a large-scale project assessing China's progress in ... Full text Link to item Cite

Anatomy of provincial level inequality in maternal mortality in China during 2004-2016: a new decomposition analysis.

Journal Article BMC Public Health · May 24, 2020 BACKGROUND: The maternal mortality ratio (MMR) is an important indicator of maternal health and socioeconomic development. Although China has experienced a large decline in MMR, substantial disparities across regions are still apparent. This study aims to ... Full text Open Access Link to item Cite

Engaging village health workers in non-communicable disease (NCD) prevention and control in Vietnam: A qualitative study.

Journal Article Glob Public Health · April 2020 The burden of non-communicable diseases (NCDs) continues to grow in Vietnam, and reducing the burden of NCDs is a national priority. This study explored perspective of community health workers (CHWs), known as Village Health Workers (VHWs) in Vietnam, and ... Full text Link to item Cite

A New Financing Model for Tuberculosis (TB) Care in China: Challenges of Policy Development and Lessons Learned from the Implementation.

Journal Article Int J Environ Res Public Health · February 21, 2020 Background: With support from the Gates Foundation, the Chinese Center for Disease Control and Prevention (China CDC) introduced a new financing model for tuberculosis (TB) care. This paper reviews the development of the associated financing policies and p ... Full text Link to item Cite

Child Nutrition Trends Over the Past Two Decades and Challenges for Achieving Nutrition SDGs and National Targets in China.

Journal Article Int J Environ Res Public Health · February 11, 2020 BACKGROUND: The objectives of the current study were to identify the trends in child nutrition, the gaps in achieving child nutrition-related goals, and implications for program and policy options for the Chinese government. METHODS: Eight child nutrition- ... Full text Link to item Cite

Trends and socio-economic disparities in catastrophic health expenditure and health impoverishment in China: 2010 to 2016.

Journal Article Trop Med Int Health · February 2020 OBJECTIVES: To investigate trends and socio-economic disparities in the catastrophic health expenditure (CHE) and health impoverishment in China after major reform of the health system and to examine the impacts of the chronic disease on CHE and impoverish ... Full text Link to item Cite

Burden of ischemic heart disease and stroke attributable to exposure to atmospheric PM2.5 in Hubei province, China

Journal Article Atmospheric Environment · January 15, 2020 Studies on mortality and disability-adjusted life years (DALYs) of cardiovascular diseases (CVDs) attributable to exposure to ambient PM2.5 in China are very limited. This study aims to provide a city-level estimation of the PM2.5-related disease burden of ... Full text Cite

Inequity in healthcare needs, health service use and financial burden of medical expenditures in China: results from a consecutive household monitoring study in Jiangsu Province.

Journal Article BMC Health Serv Res · December 16, 2019 BACKGROUND: Although public medical insurance covers over 95% of the population in China, disparities in health service use and out-of-pocket (OOP) health expenditure across income groups are still widely observed. This study aims to investigate the socio- ... Full text Link to item Cite

Under-reporting of TB cases and associated factors: a case study in China.

Journal Article BMC Public Health · December 11, 2019 BACKGROUND: Tuberculosis is a leading cause of death worldwide and has become a high global health priority. Accurate country level surveillance is critical to ending the pandemic. Effective routine reporting systems which track the course of the epidemic ... Full text Link to item Cite

Transforming tuberculosis (TB) service delivery model in China: issues and challenges for health workforce.

Journal Article Hum Resour Health · November 12, 2019 BACKGROUND: China's TB control system has been transforming its service delivery model from CDC (Centers for Disease Control and Prevention)-led model to the designated hospital-led model to combat the high disease burden of TB. The implications of the new ... Full text Link to item Cite

Current situation and progress toward the 2030 health-related Sustainable Development Goals in China: A systematic analysis.

Journal Article PLoS Med · November 2019 BACKGROUND: The Sustainable Development Goals (SDGs), adopted by all United Nations (UN) member states in 2015, established a set of bold and ambitious health-related targets to achieve by 2030. Understanding China's progress toward these targets is critic ... Full text Link to item Cite

Over- and under-treatment of TB patients in Eastern China: an analysis based on health insurance claims data.

Journal Article Trop Med Int Health · September 2019 OBJECTIVE: Poor compliance with existing guidelines for tuberculosis (TB) care and treatment is an issue of concern in China. We assessed health service use by TB patients over the entire treatment process and compared it to the recommended guidelines. MET ... Full text Link to item Cite

The impact of increased reimbursement rates under the new cooperative medical scheme on the financial burden of tuberculosis patients.

Journal Article Infect Dis Poverty · August 2, 2019 BACKGROUND: Tuberculosis (TB) is still a major public health problem in China. To scale up TB control, an innovative programme entitled the 'China-Gates Foundation Collaboration on TB Control in China was initiated in 2009. During the second phase of the p ... Full text Link to item Cite

The Effect of an Innovative Financing and Payment Model for Tuberculosis Patients on Health Service Utilization in China: Evidence from Hubei Province of China.

Journal Article Int J Environ Res Public Health · July 12, 2019 Background: Tuberculosis (TB) remains a major social and public health problem in China. The "China-Gates TB Project" started in 2012, and one of its objectives was to reduce the financial burden on TB patients and to improve access to quality TB care. The ... Full text Link to item Cite

Is tuberculosis patients management improved in the integrated TB control model in West China? A survey in Guizhou Province, China.

Journal Article Infect Dis Poverty · July 2, 2019 BACKGROUND: Tuberculosis (TB) patient management (TPM) is crucial to improve patient compliance to treatment. The coverage of TPM delivered by TB dispensaries or Centers for Disease Control and Prevention (CDC) was not high under the previous CDC model of ... Full text Link to item Cite

Strengthening public health services to achieve universal health coverage in China.

Journal Article BMJ · June 21, 2019 Better integration of public health and medical services and greater focus on quality of services are needed to make further progress on health outcomes, say Beibei Yuan and colleagues ... Full text Link to item Cite

Impact of an innovative tuberculosis financing and payment model on health service utilization by tuberculosis patients in China: do the poor fare better than the rich?

Journal Article Infect Dis Poverty · June 11, 2019 BACKGROUND: Tuberculosis (TB) prevalence is closely associated with poverty in China, and poor patients face more barriers to treatment. Using an insurance-based approach, the China-Gates TB program Phase II was implemented between 2012 and 2014 in three c ... Full text Link to item Cite

Expression of Wheat Gibberellins 2-oxidase Gene Induced Dwarf or Semi-dwarf Phenotype in Rice

Journal Article Cereal Research Communications · June 1, 2019 Gibberellins (GAs) are a class of plant hormones that play important roles in diverse aspects during plant growth and development. A series of GA synthesis and metabolism genes have been reported or proved to have essential functions in different plant spe ... Full text Cite

China's Belt and Road Initiative: Incorporating public health measures toward global economic growth and shared prosperity.

Journal Article Glob Health J · June 2019 The unprecedented globalization of trade, travel, climate change, protectionism, and geopolitical populism, as well as pandemic health threats are no longer issues for a single nation. In the field of public health, China's Belt and Road Initiative (BRI) o ... Full text Link to item Cite

Nitrogen fertilizer at heading stage effectively compensates for the deterioration of rice quality by affecting the starch-related properties under elevated temperatures.

Journal Article Food Chem · March 30, 2019 Relevant evidence of rice quality responses to increased temperatures under field condition has been obtained in our previous study. Understanding the intrinsic mechanism of increased temperatures and fertilizer treatment in regulating rice quality formati ... Full text Link to item Cite

Impact of an innovative financing and payment model on tuberculosis patients' financial burden: is tuberculosis care more affordable for the poor?

Journal Article Infect Dis Poverty · March 24, 2019 BACKGROUND: In response to the high financial burden of health services facing tuberculosis (TB) patients in China, the China-Gates TB project, Phase II, has implemented a new financing and payment model as an important component of the overall project in ... Full text Link to item Cite

Analysis of strategies to attract and retain rural health workers in Cambodia, China, and Vietnam and context influencing their outcomes.

Journal Article Hum Resour Health · January 7, 2019 BACKGROUND: Many Asia-Pacific countries are experiencing rapid changes in socio-economic and health system development. This study aims to describe the strategies supporting rural health worker attraction and retention in Cambodia, China, and Vietnam and e ... Full text Link to item Cite

Residential greenness and mortality in oldest-old women and men in China: a longitudinal cohort study.

Journal Article Lancet Planet Health · January 2019 BACKGROUND: Exposure to natural vegetation, or greenness, might affect health through several pathways, including increased physical activity and social engagement, improved mental health, and reductions in exposure to air pollution, extreme temperatures, ... Full text Link to item Cite

Tracking development assistance for health from China, 2007-2017.

Journal Article BMJ Glob Health · 2019 INTRODUCTION: In recent years, China has increased its international engagement in health. Nonetheless, the lack of data on contributions has limited efforts to examine contributions from China. Existing estimates that track development assistance for heal ... Full text Link to item Cite

Mortality Trends in Colorectal Cancer in China During 2000-2015: A Joinpoint Regression and Age-Period-Cohort Analysis.

Journal Article Prev Chronic Dis · December 13, 2018 INTRODUCTION: As lifestyles have increasingly become westernized in China, public health strategies have increasingly focused on cancer prevention. The objective of this study was to describe trends in colorectal cancer (CRC) mortality and the age, period, ... Full text Link to item Cite

Open-field warming regulates the morphological structure, protein synthesis of grain and affects the appearance quality of rice

Journal Article Journal of Cereal Science. · November 2018 Due to the sensitivity of chalk formation to high temperatures, the global warming will further threaten the improvement of high chalky grain rate in the southern japonica region of China. There have been many studies reported on the role of starch in the ... Full text Cite

Barriers and Facilitators of Engaging Community Health Workers in Non-Communicable Disease (NCD) Prevention and Control in China: A Systematic Review (2006⁻2016).

Journal Article Int J Environ Res Public Health · October 26, 2018 Background: Non-communicable diseases (NCDs) have become a dominant disease burden in China. Although China has a prevention-centered NCD strategy, the implementation effect in the community has been subjected to manpower and financial difficulties. Engagi ... Full text Link to item Cite

Evaluation of a consulting training course for international development assistance for health.

Journal Article BMC Med Educ · October 11, 2018 BACKGROUND: Development assistance for health (DAH) is an important component of foreign assistance. International health consultants usually play a key role in the international DAH field. However, there is still a shortage of consulting training in China ... Full text Link to item Cite

Combined controlled-released nitrogen fertilizers and deep placement effects of N leaching, rice yield and N recovery in machine-transplanted rice

Journal Article Agriculture, Ecosystems and Environment. · October 2018 In the Taihu region of China, overuse of chemical nitrogen (N) fertilizer is often associated with low nitrogen recovery (NRE) and leads to serious groundwater pollution caused by N leaching losses. Controlled-released nitrogen fertilizers (CRNFs) and mech ... Full text Cite

Experiences and challenges in the health protection of medical teams in the Chinese Ebola treatment center, Liberia: a qualitative study.

Journal Article Infect Dis Poverty · August 16, 2018 BACKGROUND: Health care workers are at the frontline in the fight against infectious disease, and as a result are at a high risk of infection. During the 2014-2015 Ebola outbreak in West Africa, many health care workers contracted Ebola, some fatally. Howe ... Full text Link to item Cite

Exogenous spermidine enhances the photosynthetic and antioxidant capacity of rice under heat stress during early grain-filling period.

Journal Article Funct Plant Biol · August 2018 High temperature has adverse effects on rice growth by inhibiting the flag leaf photosynthetic and antioxidant capacity, which can be alleviated by various exogenous chemicals such as spermidine (Spd). However, the role of Spd in conferring heat tolerance ... Full text Link to item Cite

Strengthening maternal and child health in China: Lessons from transforming policy proposals into action.

Journal Article Biosci Trends · May 13, 2018 China has made impressive achievements in improving maternal and child health (MCH) over the past few decades. This paper uses a policy lens to examine reasons for these achievements as well as barriers to further success. We found that strong governmental ... Full text Link to item Cite

Effects of open-field warming during grain-filling stage on grain quality of two japonica rice cultivars in lower reaches of Yangtze River delta

Journal Article Journal of Cereal Science. · May 2018 To evaluate the actual and comprehensive response of rice grain quality to global warming in lower reaches of Yangtze River delta, a 3-year open-field warming experiment was conducted with two japonica rice cultivars using Free-air temperature enhancement ... Full text Cite

A framework for comparative analysis of health systems: experiences from the Asia Pacific Observatory on Health Systems and Policies.

Journal Article WHO South East Asia J Public Health · April 2018 Drawing on published work from the Asia Pacific Observatory on Health Systems and Policies, this paper presents a framework for undertaking comparative studies on the health systems of countries. Organized under seven types of research approaches, such as ... Full text Link to item Cite

Delivery of public health services by community health workers (CHWs) in primary health care settings in China: a systematic review (1996-2016).

Journal Article Glob Health Res Policy · 2018 BACKGROUND: Community Health Workers (CHWs) have been widely used in response to the shortage of skilled health workers especially in resource limited areas. China has a long history of involving CHWs in public health intervention project. CHWs in China ca ... Full text Link to item Cite

Effect of Nitrogen and Silicon on Rice Submerged at Tillering Stage

Journal Article Agronomy journal · January 2018 CORE IDEAS: Basal silicon promotes rice growth and development at the tillering stage.After flooding, foliar spraying N or silicon timely had a better effect.Foliar spraying N had more advantages than silicon. Flooding is a major threat to rice (Oryza sati ... Full text Cite

Effects of culm carbohydrate partitioning on basal stem strength in a high-yielding rice population

Journal Article Crop Journal · December 1, 2017 Rice culm carbohydrate transport can simultaneously affect grain filling and stem lodging resistance by regulating non-structural carbohydrate (NSC) and structural carbohydrate (SC) contents. However, the relationship between carbohydrate transposition and ... Full text Cite

Financial burden of healthcare for cancer patients with social medical insurance: a multi-centered study in urban China.

Journal Article Int J Equity Health · October 10, 2017 BACKGROUND: Cancer accounts for one-fifth of the total deaths in China and brings heavy financial burden to patients and their families. Chinese government has made strong commitment to develop three types of social medical insurance since 1997 and recentl ... Full text Open Access Link to item Cite

Nitrogen fertilizer application affects lodging resistance by altering secondary cell wall synthesis in japonica rice (Oryza sativa).

Journal Article J Plant Res · September 2017 Stem mechanical strength is an important agricultural quantitative trait that is closely related to lodging resistance in rice, which is known to be reduced by fertilizer with higher levels of nitrogen. To understand the mechanism that regulates stem mecha ... Full text Link to item Cite

Application of Nitrogen Fertilizer at Heading Stage Improves Rice Quality under Elevated Temperature during Grain‐Filling Stage

Journal Article Crop science · July 2017 Global warming would deteriorate rice (Oryza sativa L.) quality, especially chalk characteristic. To better cope with the challenges from global warming, the effects of nitrogen (N) fertilizer at heading stage on rice quality under elevated temperature dur ... Full text Cite

The value of China-Africa health development initiatives in strengthening "One Health" strategy.

Journal Article Glob Health J · June 2017 Implementing national to community-based "One Health" strategy for human, animal and environmental challenges and migrating-led consequences offer great opportunities, and its value of sustained development and wellbeing is an imperative. "One Health" stra ... Full text Link to item Cite

Effects of soilless substrates on seedling quality and the growth of transplanted super japonica rice

Journal Article Journal of Integrative Agriculture · May 1, 2017 This study was conducted to investigate the effects of soilless substrates of hydroponically grown long-mat seedlings (HLMS) on seedling quality and field growth characteristics of transplanted super japonica rice. A widely grown conventional super japonic ... Full text Cite

Effects of different controlled-release nitrogen fertilisers on ammonia volatilisation, nitrogen use efficiency and yield of blanket-seedling machine-transplanted rice

Journal Article Field Crops Research. · April 2017 Recently, a novel controlled-release N fertiliser (CRNF) application method using basal CRNF combined with urea top-dressing at the tillering stage has been proposed to enhance rice yield and N use efficiency (NUE). However, its effect on ammonia volatilis ... Full text Cite

Influencing factors of health seeking intention among patients with type 2 diabetes in Chongqing Chronic Disease Management System

Journal Article Fudan University Journal of Medical Sciences · March 25, 2017 Objective: To investigate the health seeking intention and its influencing factors among patients with type 2 diabetes in Chongqing Chronic Disease Management System. Methods: Multi-stage cluster random sampling was used to investigate basic information, d ... Full text Cite

The HIV/AIDS epidemic among young people in China between 2005 and 2012: results of a spatial temporal analysis.

Journal Article HIV Med · March 2017 OBJECTIVES: Despite a recent increase in the HIV/AIDS epidemic among young people in China, youth-specific HIV data are limited. METHODS: In total, 56 621 individuals with HIV/AIDS, aged 15-24 years, registered in the Case Reporting System of China between ... Full text Link to item Cite

Case management of patients with Type 2 diabetes mellitus: a cross-sectional survey in Chongqing, China.

Journal Article BMC Health Serv Res · February 11, 2017 BACKGROUND: Type 2 diabetes mellitus has been identified as one of the priority diseases and included in the essential public health service package in China. This study investigated the frequency of follow-up visits and contents of care for case managemen ... Full text Open Access Link to item Cite

Shading Contributes to the Reduction of Stem Mechanical Strength by Decreasing Cell Wall Synthesis in Japonica Rice (Oryza sativa L.).

Journal Article Front Plant Sci · 2017 Low solar radiation caused by industrial development and solar dimming has become a limitation in crop production in China. It is widely accepted that low solar radiation influences many aspects of plant development, including slender, weak stems and susce ... Full text Link to item Cite

Health care transition in urban china

Book · January 1, 2017 The on-going transition to a market economy in China is having a profound effect on health services. As a result, the government has made health one of the key policy areas, and there is now a general recognition of the need to reform urban health services ... Full text Cite

Introduction to the urban health system and review of reform initiatives

Chapter · January 1, 2017 This chapter first provides a brief introduction to the evolution of urban health services and health insurance schemes which have been developed since the foundation of the People’s Republic. It then describes and discusses the reforms of urban health ser ... Full text Cite

The cities, the people and their health

Chapter · January 1, 2017 Radical reform of the enterprise sector, especially since 1994, has resulted in far-reaching changes which have had different impacts. Multi-ownership systems have been encouraged as a means of developing a production economy in place of the original predo ... Full text Cite

The impact of health insurance reform on hospital charges: A comparison of nantong and zibo

Chapter · January 1, 2017 In order to control the rapid increase of hospital expenditure in urban areas, different reforms aiming at strengthening the role of the insurers as purchasers of health services have been proposed. These reforms were decided and implemented in the late 19 ... Full text Cite

Conclusions and recommendations

Chapter · January 1, 2017 The study took place in two out of China’s 311 cities with more than 200,000 people. Both are in the more prosperous part of the country. One has to be cautious in applying the findings to China as a whole. None the less, participants at the national meeti ... Full text Cite

The public hospitals: Policy reform, productivity and cost

Chapter · January 1, 2017 The hospital sector dominates the health care system in urban areas and consumes around 65 per cent of the total health expenditure. There was a rapid increase of 25 per cent per annum in hospital expenditures from the mid-1980s to mid-1990s (Ministry of H ... Full text Cite

Lodging Resistance of Japonica Rice (Oryza Sativa L.): Morphological and Anatomical Traits due to top-Dressing Nitrogen Application Rates.

Journal Article Rice (N Y) · December 2016 BACKGROUND: Lodging in rice production often limits grain yield and quality by breaking or bending stems. Excessive nitrogen (N) fertilizer rates are the cause of poor lodging resistance in rice, but little is known about the effect of top-dressing N appli ... Full text Link to item Cite

The effect of NCMS on catastrophic health expenditure and impoverishment from tuberculosis care in China.

Journal Article Int J Equity Health · October 18, 2016 BACKGROUND: Health expenditure for tuberculosis (TB) care often pushes households into catastrophe and poverty. New Cooperative Medical Scheme (NCMS) aims to protect households from catastrophic health expenditure (CHE) and impoverishment in rural China. T ... Full text Open Access Link to item Cite

Effect of continuous reduction of nitrogen application to a rice-wheat rotation system in the middle-lower Yangtze River region (2013–2015)

Journal Article Field crops research · September 2016 Rice (Oryza sativa L.) and wheat (Triticum aestivum L.) are two stable food crops that play a vital role in national food security. Summer rice-winter wheat double-cropping rotation is the dominant crop rotation practice used in the middle-lower Yangtze Ri ... Full text Cite

Quality and Field Growth Characteristics of Hydroponically Grown Long-Mat Seedlings

Journal Article Agronomy journal · July 2016 Looming labor shortages and lower efficiency demand a shift from the cultivation of seedlings via the traditional nutritive soil method (CK) to hydroponically grown long-mat seedlings (HLMS), a new method of raising rice (Oriza sativa L.) seedlings. This s ... Full text Cite

Analysis of the quality of life and its influencing factors for patients with type 2 diabetes mellitus in urban and rural areas in Chongqing

Journal Article Journal of Shanghai Jiaotong University (Medical Science) · June 28, 2016 Objective: To survey the quality of life in patients with diabetes from urban and rural areas in Chongqing, discuss associated influencing factors, and provide evidence for improving the quality of life in diabetic patients. Methods: The multi-stage cluste ... Full text Cite

Are tuberculosis patients adherent to prescribed treatments in China? Results of a prospective cohort study.

Journal Article Infect Dis Poverty · May 5, 2016 BACKGROUND: Tuberculosis (TB) patients face numerous difficulties adhering to the long-term, rigorous TB treatment regimen. Findings on TB patients' treatment adherence vary across existing literature and official reports. The present study attempted to de ... Full text Open Access Link to item Cite

Top-dressing nitrogen fertilizer rate contributes to decrease culm physical strength by reducing structural carbohydrate content in japonica rice

Journal Article Journal of integrative agriculture. · May 2016 Lodging is an important factor limiting rice yield and quality by bending or breaking stem in japonica rice (Oryza sativa L.) production. The objectives of this study were to determine the mechanism of lodging resistance in japonica rice as affected by car ... Full text Cite

Comparison of physicochemical characteristics between white-belly and white-core rice grains

Journal Article Journal of cereal science · May 2016 Using white-belly and white-core mutants of a japonica rice cultivar Wuyujing3, this study was conducted to compare the physicochemical properties of grains differing in chalkiness type. Chalky grains were larger in length, width, and thickness than the tr ... Full text Cite

Towards universal access to skilled birth attendance: the process of transforming the role of traditional birth attendants in Rural China.

Journal Article BMC Pregnancy Childbirth · March 21, 2016 BACKGROUND: Institution-based childbirth, with the ultimate goal of universal access to skilled birth attendance (SBA), has been selected as a key strategy to reduce the maternal mortality rate in many developing countries. However, the question of how to ... Full text Open Access Link to item Cite

Charactering protein fraction concentrations as influenced by nitrogen application in low-glutelin rice cultivars

Journal Article Journal of integrative agriculture. · March 2016 To optimize both grain yield and quality of low-glutelin rice cultivars under N-fertilizer strategies, two-year field experiments involving three low-glutelin rice cultivars (W1240, W1721, W025) and an ordinary rice cultivar (H9405) with five N treatments ... Full text Cite

Access to and affordability of healthcare for TB patients in China: issues and challenges.

Journal Article Infect Dis Poverty · January 29, 2016 This paper introduces the background, aim and objectives of the project entitled "China-the Gates Foundation Collaboration on TB Control in China" that has been underway for many years. It also summarizes the key findings of the nine papers included in thi ... Full text Open Access Link to item Cite

The impact of the new cooperative medical scheme on financial burden of tuberculosis patients: evidence from six counties in China.

Journal Article Infect Dis Poverty · January 28, 2016 BACKGROUND: Tuberculosis (TB) patients in China encounter heavy financial burdens throughout the course of their treatment and it is unclear how China's health insurance systems affect the alleviation of this burden under the integrated approach. This stud ... Full text Link to item Cite

Factors that determine catastrophic expenditure for tuberculosis care: a patient survey in China.

Journal Article Infect Dis Poverty · January 25, 2016 BACKGROUND: Tuberculosis (TB) often causes catastrophic economic effects on both the individual suffering the disease and their households. A number of studies have analyzed patient and household expenditure on TB care, but there does not appear to be any ... Full text Link to item Cite

Implementing a "free" tuberculosis (TB) care policy under the integrated model in Jiangsu, China: practices and costs in the real world.

Journal Article Infect Dis Poverty · January 22, 2016 BACKGROUND: In the 1990s, China introduced a "free" tuberculosis (TB) care policy under the national TB control program. Recently, as a part of a new TB diagnosis and treatment model, it has been recommended that the integrated model scale up. This paper e ... Full text Link to item Cite

Global implications of China's healthcare reform.

Journal Article Int J Health Plann Manage · 2016 The ongoing healthcare reform in China has a powerful spillover effect beyond the health sector and the borders of China. A successful completion of the Chinese reform will offer a new model for social justice development, shift the global economy toward s ... Full text Link to item Cite

Impact of Community-Based DOT on Tuberculosis Treatment Outcomes: A Systematic Review and Meta-Analysis.

Journal Article PLoS One · 2016 BACKGROUND: Poor adherence to tuberculosis (TB) treatment can lead to prolonged infectivity and poor treatment outcomes. Directly observed treatment (DOT) seeks to improve adherence to TB treatment by observing patients while they take their anti-TB medica ... Full text Open Access Link to item Cite

Effect of Removing Superior Spikelets on Grain Filling of Inferior Spikelets in Rice.

Journal Article Front Plant Sci · 2016 Large-panicle rice cultivars often fail to reach their yield potential due to the poor grain filling of inferior spikelets (IS). Thus, it is important to determine the causes of poor IS grain filling. In this study, we attempted to identify whether inferio ... Full text Link to item Cite

Triacontanol Reduces Transplanting Shock in Machine-Transplanted Rice by Improving the Growth and Antioxidant Systems.

Journal Article Front Plant Sci · 2016 Machine transplantation results in serious transplant shock in seedlings and results in a longer recover stage, which negatively impacts the growth of low-position tillers and the yield of machine-transplanted rice. A barrel experiment was conducted to exa ... Full text Link to item Cite

Yield and Nitrogen Uptake of Bowl-Seedling Machine-Transplanted Rice with Slow-Release Nitrogen Fertilizer

Journal Article Agronomy journal · January 2016 Slow-release N fertilizer is considered an effective method of improving the N use efficiency (NUE). To investigate yield and N uptake of bowl-seedling machine-transplanted rice (Oryza sativa L.) with slow-release N fertilizer, three fertilizers treatments ... Full text Cite

Analysis of the equity of emergency medical services: a cross-sectional survey in Chongqing city.

Journal Article Int J Equity Health · December 21, 2015 BACKGROUND: Due to reform of the economic system and the even distribution of available wealth, emergency medical services (EMS) experienced greater risks in equity. This study aimed to assess the equity of EMS needs, utilisation, and distribution of relat ... Full text Open Access Link to item Cite

Factors contributing to the rapid rise of caesarean section: a prospective study of primiparous Chinese women in Shanghai.

Journal Article BMJ Open · November 13, 2015 OBJECTIVE: To identify factors contributing to the rapid rise of caesarean section in Shanghai through the prospective observation of changes in the preferred mode of delivery in pregnancy among primiparous Chinese women. DESIGN: Prospective study. SETTING ... Full text Link to item Cite

A survey on quality of life in patients with primary hypertension in Chongqing and its influential factors

Journal Article Fudan University Journal of Medical Sciences · November 1, 2015 Objective: To explore the quality of life (QOL) in patients with primary hypertension and its influence factors in Chongqing, so as to provide scientific evidence for disease control and prevention. Methods: By using multistage sampling, QOL scores of 586 ... Full text Cite

Effect of nitrogen management during the panicle stage in rice on the nitrogen utilization of rice and succeeding wheat crops

Journal Article European Journal of Agronomy. · October 2015 The main objectives of this paper were to investigate the absorption and utilization of nitrogen applied at the panicle stage in rice for promoting and protecting spikelet and the effect of residual nitrogen on the utilization of nitrogen in the succeeding ... Full text Cite

A host plant genome (Zizania latifolia) after a century-long endophyte infection.

Journal Article Plant J · August 2015 Despite the importance of host-microbe interactions in natural ecosystems, agriculture and medicine, the impact of long-term (especially decades or longer) microbial colonization on the dynamics of host genomes is not well understood. The vegetable crop 'J ... Full text Link to item Cite

Nitrogen effect on amino acid composition in leaf and grain of japonica rice during grain filling stage

Journal Article Journal of cereal science · July 2015 This paper reports the effect of nitrogen on amino acid composition of leaf and grain for japonica rice during the grain filling stage, using pot experiments with three N rate treatments. Dynamic changes of free amino acids (FAA) and protein amino acids (P ... Full text Cite

Public-private mix for tuberculosis care and control: a systematic review.

Journal Article Int J Infect Dis · May 2015 BACKGROUND: Public-private mix (PPM), recommended by the World Health Organization (WHO), was introduced to cope with the tuberculosis (TB) epidemic worldwide. In many developing countries, PPM has played a powerful role in TB control, while in others it h ... Full text Link to item Cite

Comparison between peer-led and teacher-led education in tuberculosis prevention in rural middle schools in Chongqing, China.

Journal Article Asia Pac J Public Health · March 2015 The aim of this study was to investigate the efficacy of tuberculosis (TB) education through a comparison of peer-led and teacher-led methods of education about TB prevention among middle school students in rural Chongqing, China. A preintervention and pos ... Full text Link to item Cite

A Proteomic Approach to Analyze Differential Regulation of Proteins During Bud Outgrowth Under Apical Dominance Based on the Auxin Transport Canalization Model in Rice (Oryza sativa L.)

Journal Article Journal of Plant Growth Regulation · March 1, 2015 Apical dominance refers to the inhibition of shoot branching by the dominant shoot apex. The underlying mechanisms of apical dominance, especially in rice (Oryza sativa), remain a subject of debate. Here, we studied apical dominance in the indica rice vari ... Full text Cite

Systematic review on irrational use of medicines in China and Vietnam.

Journal Article PLoS One · 2015 BACKGROUND: Irrational use of medicines has been an issue concerned all over the world and the outlooks in developing countries are more severe. This study aimed to assess the different patterns of irrational use of medicines and its influential factors in ... Full text Link to item Cite

Tackling challenges of TB/MDRTB in China: concerted actions are imperative.

Journal Article Infect Dis Poverty · 2015 China is the second largest TB epidemic with the most number of people infected with multi-drug resistant (MDR). Over the past decade, a large number of TB control projects have been funded by the government of China and international organizations, and ep ... Full text Link to item Cite

Exogenous spermidine alleviates oxidative damage and reduce yield loss in rice submerged at tillering stage.

Journal Article Front Plant Sci · 2015 To figure out whether spermidine (Spd) can alleviate oxidative damage on rice (Oryza sativa L.) caused by submergence stress, Ningjing 3 was used in this study. The results showed that, spraying Spd on rice leaves at a concentration of 0.5 mM promoted the ... Full text Link to item Cite

Quantitative imaging of selenoprotein with Multi-isotope imaging mass spectrometry (MIMS)

Conference Surface and Interface Analysis · November 1, 2014 Multi-isotope imaging mass spectrometry (MIMS) allows high-resolution quantitative imaging of protein and nucleic acid synthesis at the level of a single cell using stable isotope labels.We employedMIMS to determine the compartmental localization of seleno ... Full text Cite

China's distinctive engagement in global health.

Journal Article Lancet · August 30, 2014 China has made rapid progress in four key domains of global health. China's health aid deploys medical teams, constructs facilities, donates drugs and equipment, trains personnel, and supports malaria control mainly in Africa and Asia. Prompted by the seve ... Full text Link to item Cite

Proteomic analysis of proteins related to rice grain chalkiness using iTRAQ and a novel comparison system based on a notched-belly mutant with white-belly.

Journal Article BMC Plant Biol · June 12, 2014 BACKGROUND: Grain chalkiness is a complex trait adversely affecting appearance and milling quality, and therefore has been one of principal targets for rice improvement. Eliminating chalkiness from rice has been a daunting task due to the complex interacti ... Full text Link to item Cite

Lodging resistance characteristics of high-yielding rice populations

Journal Article Field crops research · May 2014 The main objectives of this paper were to explore effective ways of improving the lodging resistance of high-yield rice populations and the lodging resistance capacity responses of different rice populations to nitrogen. Field experiments were conducted at ... Full text Cite

Equity in access to healthcare among the urban elderly in China: does health insurance matter?

Journal Article Int J Health Plann Manage · 2014 OBJECTIVE: The aim of this study was to examine if inequity in healthcare among the urban elderly in China has been improved through the implementation of Urban Resident Basic Medical Insurance (URBMI).METHODS AND DATA SOURCE: We used the data from a natio ... Full text Link to item Cite

A community-based approach to non-communicable chronic disease management within a context of advancing universal health coverage in China: progress and challenges.

Journal Article BMC Public Health · 2014 Paralleled with the rapid socio-economic development and demographic transition, an epidemic of non-communicable chronic diseases (NCDs) has emerged in China over the past three decades, resulting in increased disease and economic burdens. Over the past de ... Full text Link to item Cite

YIELD AND YIELD COMPONENTS OF HYBRID RICE AS INFLUENCED BY NITROGEN FERTILIZATION AT DIFFERENT ECO-SITES

Journal Article Journal of Plant Nutrition · January 1, 2014 Hybrid rice (Oryza sativa L.) cultivars play an important role in rice production due to its high yield potential. Optimum nitrogen (N) rate is necessary to achieve the maximum yield of hybrid. The main objective of this study was to reveal the responses o ... Full text Cite

Effects of Nitrogen Application Rate and Ratio on Lodging Resistance of Super Rice with Different Genotypes

Journal Article Journal of Integrative Agriculture · January 1, 2014 The objective of this study was to determine the morphology mechanism of nitrogen (N) fertilizer rates and ratio on lodging resistance through analying its effects among lodging index (LI), lodging-related morphological traits and physical strength in basa ... Full text Cite

Advancing universal coverage of healthcare in China: translating political will into policy and practice.

Journal Article Int J Health Plann Manage · 2014 China launched its new health system reform plan in 2009 to advance its universal coverage of healthcare, after more than 4 years' consultations and discussions with various stakeholders including the public. This paper aims to introduce and discuss the co ... Full text Link to item Cite

Does perverse economic incentive lead to the irrational uses of medicines?

Journal Article Expert Rev Pharmacoecon Outcomes Res · December 2013 Full text Link to item Cite

A mixed-method study of factors associated with differences in caesarean section rates at community level: the case of rural China.

Journal Article Midwifery · August 2013 OBJECTIVE: to assess population-based caesarean section (CS) rates in rural China and explore determinants and reasons for choosing a CS. DESIGN: cross-sectional study, quantitative and qualitative methods, statistical modelling. SETTING: two rural countie ... Full text Link to item Cite

Factors associated with patient, and diagnostic delays in Chinese TB patients: a systematic review and meta-analysis.

Journal Article BMC Med · July 2, 2013 BACKGROUND: Delay in seeking care is a major impediment to effective management of tuberculosis (TB) in China. To elucidate factors that underpin patient and diagnostic delays in TB management, we conducted a systematic review and meta-analysis of factors ... Full text Link to item Cite

Changes in health expenditures in China in 2000s: has the health system reform improved affordability.

Journal Article Int J Equity Health · June 13, 2013 BACKGROUND: China's health system reform launched in early 2000s has achieved better coverage of health insurance and significantly increased the use of healthcare for vast majority of Chinese population. This study was to examine changes in the structure ... Full text Link to item Cite

China's biggest, most neglected health challenge: Non-communicable diseases.

Journal Article Infect Dis Poverty · April 5, 2013 BACKGROUND: Over the past two decades, international health policies focusing on the fight against the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), tuberculosis (TB), malaria, and those diseases that address maternal and chil ... Full text Link to item Cite

Impact of financial and educational interventions on maternity care: results of cluster randomized trials in rural China, CHIMACA.

Journal Article Matern Child Health J · February 2013 To report on the design and basic outcomes of three interventions aimed at improving the use and quality of maternity care in rural China: financial interventions, training in clinical skills, and training in health education. Community-based cluster rando ... Full text Link to item Cite

Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation.

Journal Article Plant Physiol · February 2013 Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme of the tetrahydrofolate (THF)-mediated one-carbon (C1) metabolic network. This enzyme catalyzes the reduction of 5,10-methylene-THF to 5-methyl-THF. The latter donates its methyl group to homocyst ... Full text Link to item Cite

S-nitrosothiols and the S-nitrosoproteome of the cardiovascular system.

Journal Article Antioxid Redox Signal · January 20, 2013 SIGNIFICANCE: Since their discovery in the early 1990's, S-nitrosylated proteins have been increasingly recognized as important determinants of many biochemical processes. Specifically, S-nitrosothiols in the cardiovascular system exert many actions, inclu ... Full text Link to item Cite

Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance.

Journal Article Mol Nutr Food Res · December 2012 SCOPE: Selenium has complex effects in vivo on multiple homeostatic mechanisms such as redox balance, methylation balance, and epigenesis, via its interaction with the methionine-homocysteine cycle. In this study, we examined the hypothesis that selenium s ... Full text Link to item Cite

The incoherence of China's national health development strategies.

Journal Article Am J Public Health · December 2012 China ambitiously promised to provide safe, effective, and affordable health care services to all citizens. However, the national strategies for enhancing health remain patchy, and the policy frameworks to empower and inspire individuals and communities to ... Full text Link to item Cite

Schistosomiasis control and the health system in P.R. China.

Journal Article Infect Dis Poverty · November 1, 2012 Over the last sixty years advances have been made in the control of schistosomiasis in P.R. China. There are, however, difficult challenges still to be met. This paper looks at the extent to which the health system offers a positive environment for the con ... Full text Link to item Cite

What is quality in maternal and neonatal health care?

Journal Article Midwifery · October 2012 OBJECTIVE: to review published papers and reports examining quality of care in maternal and newborn health to identify definitions and models of quality of care. DESIGN: literature review. SEARCH STRATEGY: electronic search of MEDLINE and organisational da ... Full text Link to item Cite

Impact of alternative reimbursement strategies in the new cooperative medical scheme on caesarean delivery rates: a mixed-method study in rural China.

Journal Article BMC Health Serv Res · July 24, 2012 BACKGROUND: The rate of caesarean delivery (CD) in rural China has been rapidly increasing in recent decades. Due to the exorbitant costs associated with CD, paying for this expensive procedure is often a great challenge for the majority of rural families. ... Full text Link to item Cite

Disease control and health systems in low- and middle-income countries: enhancing positive interrelation.

Journal Article Trop Med Int Health · May 2012 There is a growing interest in improving the relationship between disease control programmes and the rest of the health system in low- and middle-income countries. This short study seeks to contribute to this movement by providing a multi-dimensional appro ... Full text Link to item Cite

Utilization of antenatal ultrasound scan and implications for caesarean section: a cross-sectional study in rural Eastern China.

Journal Article BMC Health Serv Res · April 12, 2012 BACKGROUND: Antenatal ultrasound scan is a widely accepted component of antenatal care. Studies have looked at the relationship between ultrasound scanning and caesarean section (CS) in certain groups of women in China. However, there are limited data on t ... Full text Link to item Cite

Cough it up

Journal Article Foreign Affairs · March 1, 2012 Cite

Can rural health insurance improve equity in health care utilization? A comparison between China and Vietnam.

Journal Article Int J Equity Health · February 29, 2012 INTRODUCTION: Health care financing reforms in both China and Vietnam have resulted in greater financial difficulties in accessing health care, especially for the rural poor. Both countries have been developing rural health insurance for decades. This stud ... Full text Link to item Cite

Identification of wounding and topping responsive small RNAs in tobacco (Nicotiana tabacum).

Journal Article BMC Plant Biol · February 22, 2012 BACKGROUND: MicroRNAs (miRNAs) and short interfering RNAs (siRNAs) are two major classes of small RNAs. They play important regulatory roles in plants and animals by regulating transcription, stability and/or translation of target genes in a sequence-compl ... Full text Link to item Cite

Changes and equity in use of maternal health care in China: from 1991 to 2003.

Journal Article Matern Child Health J · February 2012 To examine changes and equity in use of maternal care in different types of rural and urban areas in China from the early 1990s to early 2000s. Data were drawn from three National Health Household Interview Surveys conducted in 1993, 1998, and 2003. Analys ... Full text Link to item Cite

Controlling cost escalation of healthcare: making universal health coverage sustainable in China.

Journal Article BMC Public Health · 2012 An increasingly number of low- and middle-income countries have developed and implemented a national policy towards universal coverage of healthcare for their citizens over the past decade. Among them is China which has expanded its population coverage by ... Full text Link to item Cite

On residents' satisfaction with community health services after health care system reform in Shanghai, China, 2011.

Journal Article BMC Public Health · 2012 BACKGROUND: Health care system reform is a major issue in many countries and therefore how to evaluate the effects of changes is incredibly important. This study measured residents' satisfaction with community health care service in Shanghai, China, and ai ... Full text Link to item Cite

Is systematic review an effective tool for evidence-based health system research in developing countries?

Journal Article Chinese Journal of Evidence-Based Medicine · July 7, 2011 An increasing number of health system researchers use systematic review to synthesize research evidence to inform the development of health policies at global and national levels. However, there are methodological challenges facing the health system resear ... Cite

Patient medical costs for tuberculosis treatment and impact on adherence in China: a systematic review.

Journal Article BMC Public Health · May 26, 2011 BACKGROUND: Charging for tuberculosis (TB) treatment could reduce completion rates, particularly in the poor. We identified and synthesised studies that measure costs of TB treatment, estimates of adherence and the potential impact of charging on treatment ... Full text Link to item Cite

Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo.

Journal Article Circulation · May 10, 2011 BACKGROUND: Glutathione peroxidase-3 (GPx-3) is a selenocysteine-containing plasma protein that scavenges reactive oxygen species in the extracellular compartment. A deficiency of this enzyme has been associated with platelet-dependent thrombosis, and a pr ... Full text Link to item Cite

Giving birth at a health-care facility in rural China: is it affordable for the poor?

Journal Article Bull World Health Organ · February 1, 2011 OBJECTIVE: To investigate changes in the expenditure of giving birth in health-care facilities in rural China during 1998-2007, to examine the financial burden on households, particularly poor ones, and to identify factors associated with out-of-pocket exp ... Full text Link to item Cite

Trends in smoking and quitting in China from 1993 to 2003: National Health Service Survey data.

Journal Article Bull World Health Organ · October 1, 2010 OBJECTIVE: China has about 350 million smokers, more commonly men. Using data from National Health Service Surveys conducted in 1993, 1998 and 2003, we (i) estimated trends in smoking prevalence and cessation according to sociodemographic variables and (ii ... Full text Link to item Cite

Utilisation of maternal health care in western rural China under a new rural health insurance system (New Co-operative Medical System).

Journal Article Trop Med Int Health · October 2010 SUMMARY OBJECTIVE: To investigate factors influencing maternal health care utilisation in western rural China and its relation to income before (2002) and after (2007) introducing a new rural health insurance system (NCMS). METHODS: Data from cross-section ... Full text Link to item Cite

Availability and use of essential medicines in China: manufacturing, supply, and prescribing in Shandong and Gansu provinces.

Journal Article BMC Health Serv Res · July 17, 2010 BACKGROUND: The current health care reform in China launched in 2009 tackles the problem of access to appropriate medicines for its 1.3 billion people by focusing on providing essential medicines to all. To provide evidence for the reform process, we inves ... Full text Link to item Cite

How does the New Cooperative Medical Scheme influence health service utilization? A study in two provinces in rural China.

Journal Article BMC Health Serv Res · May 10, 2010 BACKGROUND: Many countries are developing health financing mechanisms to pursue the goal of universal coverage. In China, a rural health insurance system entitled New Cooperative Medical Scheme (NCMS) is being developed since 2003. Although there is concer ... Full text Link to item Cite

How effectively can the New Cooperative Medical Scheme reduce catastrophic health expenditure for the poor and non-poor in rural China?

Journal Article Trop Med Int Health · April 2010 OBJECTIVES: China has implemented the New Cooperative Medical Scheme (NCMS) in rural areas since 2003 to provide financial protection to its rural population. This article explores the effect of NCMS on relieving catastrophic health expenditure (CHE) among ... Full text Link to item Cite

Tracking China's health reform.

Journal Article Lancet · March 27, 2010 Full text Link to item Cite

Balancing the funds in the New Cooperative Medical Scheme in rural China: determinants and influencing factors in two provinces.

Journal Article Int J Health Plann Manage · 2010 In recent years, the central government in China has been leading the re-establishment of its rural health insurance system, but local government institutions have considerable flexibility in the specific design and management of schemes. Maintaining a rea ... Full text Link to item Cite

Cesarean section delivery among primiparous women in rural China: an emerging epidemic.

Journal Article Am J Obstet Gynecol · January 2010 OBJECTIVE: The purpose of this study was to describe the trends and determinants of cesarean section (CS) delivery rates in rural China. STUDY DESIGN: Data on rural primiparous women aged 15-49 years (n = 10,754) were obtained from 3 nationwide representat ... Full text Link to item Cite

Tuberculosis patient expenditure on drugs and tests in subsidised, public services in China: a descriptive study.

Journal Article Trop Med Int Health · January 2010 OBJECTIVE: To measure patient expenditure on additional drugs and tests in public services where tuberculosis (TB) drugs are supplied for free. METHODS: Questionnaire survey of patients currently on treatment in eight TB dispensaries in two provinces; in d ... Full text Link to item Cite

Angiotensin II and hypertonicity modulate proximal tubular aquaporin 1 expression.

Journal Article Am J Physiol Renal Physiol · December 2009 Aquaporin 1 (AQP1) is the major water channel in the renal proximal tubule (PT) and thin descending limb of Henle, but its regulation remains elusive. Here, we investigated the effect of ANG II, a key mediator of body water homeostasis, on AQP1 expression ... Full text Link to item Cite

Evaluating the financial protection of patients with chronic disease by health insurance in rural China

Journal Article International Journal for Equity in Health · December 1, 2009 Background. A growing number of developing countries are developing health insurance schemes that aim to protect households, particularly the poor, from financial catastrophe and impoverishment caused by unaffordable medical care. This paper investigates t ... Full text Cite

Regulation of the extracellular antioxidant selenoprotein plasma glutathione peroxidase (GPx-3) in mammalian cells.

Journal Article Mol Cell Biochem · July 2009 Plasma glutathione peroxidase (GPx-3) is a selenocysteine-containing extracellular antioxidant protein that catalyzes the reduction of hydrogen peroxide and lipid hydroperoxides. Selenoprotein expression involves the alternate recognition of a UGA codon as ... Full text Link to item Cite

The impact of smoking and quitting on household expenditure patterns and medical care costs in China.

Journal Article Tob Control · April 2009 BACKGROUND: Smoking remains very common in Chinese men, and the economic burden caused by cigarette consumption on smokers and their families may be substantial. Using a large nationally representative household survey, the third National Health Services S ... Full text Link to item Cite

Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells.

Journal Article J Biol Chem · March 20, 2009 Hyperaldosteronism is associated with impaired endothelium-dependent vascular reactivity owing to increased reactive oxygen species and decreased bioavailable nitric oxide (NO(.)); however, the effects of aldosterone on vasodilatory signaling pathways in v ... Full text Link to item Cite

Reform of how health care is paid for in China: challenges and opportunities.

Journal Article Lancet · November 22, 2008 China's current strategy to improve how health services are paid for is headed in the right direction, but much more remains to be done. The problems to be resolved, reflecting the setbacks of recent decades, are substantial: high levels of out-of-pocket p ... Full text Link to item Cite

Tackling the challenges to health equity in China.

Journal Article Lancet · October 25, 2008 In terms of economic development, China is widely acclaimed as a miracle economy. Over a period of rapid economic growth, however, China's reputation for health has been slipping. In the 1970s China was a shining example of health development, but no longe ... Full text Link to item Cite

Barriers to accessing TB diagnosis for rural-to-urban migrants with chronic cough in Chongqing, China: a mixed methods study.

Journal Article BMC Health Serv Res · October 2, 2008 BACKGROUND: China is facing a significant tuberculosis epidemic among rural-to-urban migrants, which poses a threat to TB control. This study aimed to understand the health seeking behaviour of and health systems responses to migrants and permanent urban r ... Full text Link to item Cite

Treatment seeking for symptoms suggestive of TB: comparison between migrants and permanent urban residents in Chongqing, China.

Journal Article Trop Med Int Health · July 2008 OBJECTIVES: To understand the health-seeking behaviour of rural-to-urban migrants with chronic cough in Chongqing city, and compare this with the permanent urban population taking into account the socioeconomic factors influencing delays in access to healt ... Full text Link to item Cite

How affordable are tuberculosis diagnosis and treatment in rural China? An analysis from community and tuberculosis patient perspectives.

Journal Article Trop Med Int Health · December 2007 OBJECTIVES: To assess equity in access to tuberculosis (TB) care by estimating and comparing the direct household costs perceived by community residents with actual costs experienced by TB patients and to identify the factors influencing the financial burd ... Full text Link to item Cite

Hospitalisation among the elderly in urban China.

Journal Article Health Policy · December 2007 OBJECTIVES: The aim of this study was to examine the trend of hospitalisation amongst the elderly in urban China and analyse the main socio-economic factors which are affecting the use of inpatient care. METHODS: Data from the Chinese national household he ... Full text Link to item Cite

Multiple perspectives on diagnosis delay for tuberculosis from key stakeholders in poor rural China: case study in four provinces.

Journal Article Health Policy · July 2007 This study aims to understand the contextual barriers to accessing timely TB diagnosis after first seeking care, especially among the poor and vulnerable in rural China. Both quantitative and qualitative methods were used to elicit the experiences and pers ... Full text Link to item Cite

Perceptions of tuberculosis and health seeking behaviour in rural Inner Mongolia, China.

Journal Article Health Policy · May 2007 PURPOSE: This study aimed to explore perceptions of TB, and health care seeking pathways, among poor rural communities in Inner Mongolia. METHODOLOGY: Twenty focus group discussions (FGDs) were held and 105 farmers were included. Six hundred and fourteen r ... Full text Link to item Cite

Urban health insurance reform and coverage in China using data from National Health Services Surveys in 1998 and 2003.

Journal Article BMC Health Serv Res · March 3, 2007 BACKGROUND: In 1997 there was a major reform of the government run urban health insurance system in China. The principal aims of the reform were to widen coverage of health insurance for the urban employed and contain medical costs. Following this reform t ... Full text Link to item Cite

Persistent problems of access to appropriate, affordable TB services in rural China: experiences of different socio-economic groups.

Journal Article BMC Public Health · February 8, 2007 BACKGROUND: Large-scale Tuberculosis (TB) control programmes in China have been hailed a success. Concerns remain, however, about whether the programme is reaching all sections of the population, particularly poorer groups within rural communities, and whe ... Full text Link to item Cite

Equity impacts of neoliberal reforms: what should the policy responses be?

Journal Article Int J Health Serv · 2007 The final article in this special section draws together the lessons learned from the ALPS analyses and considers a range of potential policy responses. The country case studies highlight that health systems in many low- and middle-income countries are fai ... Full text Link to item Cite

Vietnam during economic transition: a tracer study of health service access and affordability.

Journal Article Int J Health Serv · 2007 For many decades, Vietnam had a well-structured public health service with extensive population coverage, with free care at government health facilities until 1989. Since then the country has been going through economic transition, including major changes ... Full text Link to item Cite

Rising cesarean delivery rate in primiparous women in urban China: evidence from three nationwide household health surveys.

Journal Article Am J Obstet Gynecol · December 2006 OBJECTIVE: To examine the trend in the rate of cesarean delivery in primiparous women and to analyse individual socioeconomic factors driving the escalation of cesarean delivery rates in urban China. STUDY DESIGN: Data were drawn from three national househ ... Full text Link to item Cite

Does decentralisation improve human resource management in the health sector? A case study from China.

Journal Article Soc Sci Med · October 2006 A major obstacle to the provision of health services is lack of an effective workforce. Human resource management (HRM) can improve the effectiveness of the workforce, though this is difficult in large bureaucratic organisations. Decentralisation is a comm ... Full text Link to item Cite

Factors affecting delays in tuberculosis diagnosis in rural China: a case study in four counties in Shandong Province.

Journal Article Trans R Soc Trop Med Hyg · May 2005 Improving case detection is an urgent and serious challenge for tuberculosis (TB) control in China. We investigated the extent to which TB patients delayed seeking TB care and health services delayed reaching a diagnosis, and socio-economic factors associa ... Full text Link to item Cite

What lessons can be drawn from tuberculosis (TB) control in China in the 1990s? An analysis from a health system perspective.

Journal Article Health Policy · April 2005 China has made a significant achievement in tackling the TB epidemic over the last decade, due largely to the implementation of directly-observed treatment strategy (DOT). The cure rate of TB cases reached more than 90% for registered TB patients. However, ... Full text Link to item Cite

Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.

Journal Article J Endocrinol · December 2004 We reported previously that insulin inhibits the stimulatory effect of high glucose on the expression of angiotensinogen (ANG) gene in both rat immortalized renal proximal tubular cells (IRPTCs) and non-diabetic rat renal proximal tubular cells (RPTCs), bu ... Full text Link to item Cite

The impact of urban health insurance reform on hospital charges: a case study from two cities in China.

Journal Article Health Policy · May 2004 During the transition from a centrally planned to a market economy, China's urban health insurance system is being reformed. The control of the rapidly increasing hospital expenses will be a major determinant of the success of the reform. This study aims t ... Full text Link to item Cite

Unintended pregnancy and induced abortion among unmarried women in China: a systematic review.

Journal Article BMC Health Serv Res · January 22, 2004 BACKGROUND: Until recently, premarital examination for both men and women was a legal requirement before marriage in China. Researchers have carried out surveys of attendees' sexual activity, pregnancy and abortion before their marriages, trying to map out ... Full text Link to item Cite

Factors affecting the implementation of health legislation and its impact on the rural poor in China: a case study of implementation of the maternal and infant health care law in two poor counties.

Journal Article Int J Health Plann Manage · 2004 This paper presents and discusses a case study of health legislation in China. In the transition to a market economy, legislation has been developed to offset the weakening in the central planning mechanism and political control that have historically infl ... Full text Link to item Cite

Changing medical doctor productivity and its affecting factors in rural China.

Journal Article Int J Health Plann Manage · 2004 Using the data collected from the health facility-based survey, part of the national health service survey conducted in 1993 and 1998, this paper tries to examine changes in labour productivity among the county-level hospitals and township health centres i ... Full text Link to item Cite

High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells.

Journal Article Endocrinology · October 2003 The present study investigated whether activation of the hexosamine biosynthesis pathway might mediate at least in part the high glucose effect on angiotensinogen (ANG) gene expression and immortalized renal proximal tubular cell (IRPTC) hypertrophy. IRPTC ... Full text Link to item Cite

Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms.

Journal Article Am J Physiol Renal Physiol · March 2003 This study examined the effect of hemin on the expression of heme oxygenase-1 (HO-1) and monocyte chemoattractant protein-1 (MCP-1) in immortalized rat proximal tubular epithelial cells (IRPTCs). Hemin elicited a dose- and time-dependent induction of HO-1 ... Full text Link to item Cite

Growth factor-mediated phosphorylation of proapoptotic BAD reduces tubule cell death in vitro and in vivo.

Journal Article Kidney Int · January 2003 BACKGROUND: Exogenous growth factors administered during unilateral ureteral obstruction (UUO) in neonatal rats significantly reduce apoptosis and tubular atrophy. Because the mechanism underlying these salutary effects is largely unknown, we investigated ... Full text Link to item Cite

Insulin inhibits dexamethasone effect on angiotensinogen gene expression and induction of hypertrophy in rat kidney proximal tubular cells in high glucose.

Journal Article Endocrinology · December 2002 The present studies investigated whether insulin inhibits the stimulatory effect of dexamethasone (DEX) on angiotensinogen (ANG) gene expression and induction of hypertrophy in rat immortalized renal proximal tubular cells (IRPTCs) in a high-glucose milieu ... Full text Link to item Cite

Health equity in transition from planned to market economy in China.

Journal Article Health Policy Plan · December 2002 This paper examines the impact of economic transition and health sector reform on health equities in the urban and rural populations of China in the 1990s. Since 1980, China has experienced a rapid economic development and fundamental transformation of its ... Full text Link to item Cite

Health systems decentralization and human resources management in low and middle income countries

Journal Article Public Administration and Development · December 1, 2002 The aim of this article is to explore the experiences of human resources management in the context of health sector decentralization. The initial review of health sector decentralization covers issues relating to the context, content, formulation/implement ... Full text Cite

Mothers' perspectives on the quality of postpartum care in Central Shanghai, China.

Journal Article Int J Qual Health Care · October 2002 OBJECTIVES: To investigate mothers' perspectives on the quality of postpartum care services in central Shanghai, China. DESIGN: Semi-structured interviews. SETTING: Two maternal and child health posts in two subdistricts in LW District, Central Shanghai, C ... Full text Link to item Cite

High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells.

Journal Article Endocrinology · August 2002 The present studies investigated whether the effect of high glucose levels on angiotensinogen (ANG) gene expression in kidney proximal tubular cells is mediated via reactive oxygen species (ROS) generation and p38 MAPK activation. Rat immortalized renal pr ... Full text Link to item Cite

Monitoring changes in gene expression in renal ischemia-reperfusion in the rat.

Journal Article Kidney Int · May 2002 BACKGROUND: Although acute renal failure (ARF) is a relatively common disorder with major morbidity and mortality, its molecular basis remains incompletely defined. The present study examined global gene expression in the well-characterized ischemia-reperf ... Full text Link to item Cite

Global analysis of gene expression in renal ischemia-reperfusion in the mouse.

Journal Article Biochem Biophys Res Commun · March 8, 2002 Ischemia-induced acute renal failure (ARF) is a relatively common disorder with major morbidity and mortality. To study global gene expression during ARF, 6-week-old C57BL/6 male mice underwent 30 min of bilateral renal ischemia followed by reperfusion [I/ ... Full text Link to item Cite

Hyperglycemia induces insulin resistance on angiotensinogen gene expression in diabetic rat kidney proximal tubular cells.

Journal Article J Endocrinol · February 2002 Clinical and animal studies have shown that treatment with angiotensin-converting enzyme (ACE) inhibitors or angiotensin II (Ang II) receptor antagonists slows the progression of nephropathy in diabetes, indicating that Ang II plays an important role in it ... Full text Link to item Cite

Essential role(s) of the intrarenal renin-angiotensin system in transforming growth factor-beta1 gene expression and induction of hypertrophy of rat kidney proximal tubular cells in high glucose.

Journal Article J Am Soc Nephrol · February 2002 These studies investigated the question of whether the intrarenal renin-angiotensin system (RAS) is essential for transforming growth factor-beta1 (TGF-beta1) gene expression and induction of hypertrophy of renal proximal tubular cells in high glucose in v ... Full text Link to item Cite

Abnormal iron deposition in renal cells in the rat with chronic angiotensin II administration.

Journal Article Lab Invest · January 2002 Acute experimental iron loading causes iron to accumulate in the renal tissue. The accumulation of iron may play a role in enhancing oxidant-induced tubular injury by producing increased amounts of reactive oxygen species. From findings in cells from heme ... Full text Link to item Cite

Regulation and localization of HSP70 and HSP25 in the kidney of rats undergoing long-term administration of angiotensin II.

Journal Article Hypertension · January 2002 Various renal insults result in induction of heat shock protein (HSP) expression within the kidney. Some of the HSPs induced in that manner are postulated to have renoprotective effects via either chaperoning actions or antioxidative properties. We have pr ... Full text Link to item Cite

Changing access to health services in urban China: implications for equity.

Journal Article Health Policy Plan · September 2001 The ongoing reform of public institutions and state-owned enterprises in urban China has had a profound impact on the financing, organization and provision of health services. Access to health care by the urban population has become more inequitable. One o ... Full text Link to item Cite

Characterization of a putative insulin-responsive element and its binding protein(s) in rat angiotensinogen gene promoter: regulation by glucose and insulin.

Journal Article Endocrinology · June 2001 We previously demonstrated that high glucose activates angiotensinogen (ANG) expression and that insulin inhibits this activation. The present studies aim to investigate whether insulin regulates ANG gene expression in kidney proximal tubular cells at the ... Full text Link to item Cite

Analysis of Japanese encephalitis epidemic in Western Nepal in 1997.

Journal Article Epidemiol Infect · February 2001 We conducted an epidemiological study of a Japanese encephalitis (JE) outbreak in the southwestern part of Nepal in 1997. A high density of JE infections was found and it was estimated that 27.9% the total population were infected with JE virus in the stud ... Link to item Cite

Effect of renin-angiotensin system blockade on the expression of the angiotensinogen gene and induction of hypertrophy in rat kidney proximal tubular cells.

Journal Article Exp Nephrol · 2001 Studies have shown that high levels of glucose and angiotensin II (Ang II) stimulate hypertrophy and the expression of matrix protein genes in mouse proximal tubular cells in vitro. The present study tested the hypothesis that blockade of the renin-angiote ... Full text Link to item Cite

High levels of glucose stimulate angiotensinogen gene expression via the P38 mitogen-activated protein kinase pathway in rat kidney proximal tubular cells.

Journal Article Endocrinology · December 2000 The present studies investigated whether the effect of high levels of glucose on angiotensinogen (ANG) secretion and gene expression in kidney proximal tubular cells is mediated at least in part via the activation of p38 mitogen-activated protein kinase (p ... Full text Link to item Cite

Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection.

Journal Article Hypertension · March 2000 In this study, we investigated the regulation and physiological role of heme oxygenase-1 (HO-1) in the kidney of rats with hypertension. Rats were continuously administered either angiotensin II (Ang II) or norepinephrine with an osmotic minipump for up to ... Full text Link to item Cite

Decentralizing rural health services: a case study in China.

Journal Article Int J Health Plann Manage · 2000 Many low and middle-income countries have decentralized their public health services in an effort to improve their equity, efficiency and effectiveness. This paper presents a case study of a poor rural county in China that devolved finance and management o ... Full text Link to item Cite

Insulin inhibits angiotensinogen gene expression via the mitogen-activated protein kinase pathway in rat kidney proximal tubular cells.

Journal Article Endocrinology · November 1999 The present study aimed to investigate the molecular mechanism(s) of insulin action on angiotensinogen (ANG) secretion and gene expression in kidney proximal tubular cells exposed to high levels of glucose. Immortalized rat proximal tubular cells (IRPTC) w ... Full text Link to item Cite

Glucocorticoid metabolism in proximal tubules modulates angiotensin II-induced electrolyte transport.

Journal Article Proc Soc Exp Biol Med · June 1999 The hormonal interactions that regulate electrolyte transport in the proximal tubule are complex and incompletely understood. Since endogenous glucocorticoids and angiotensin II each can affect electrolyte transport in this renal segment, we hypothesized t ... Full text Link to item Cite

Rural health prepayment schemes in China: towards a more active role for government.

Journal Article Soc Sci Med · April 1999 A large majority of China's rural population were members of health prepayment schemes in the 1970's. Most of these schemes collapsed during the transition to a market economy. Some localities subsequently reestablished schemes. In early 1997 a new governm ... Full text Link to item Cite

Rat proximal tubule cell line transformed with origin-defective SV40 DNA: autocrine ANG II feedback.

Journal Article Am J Physiol · February 1999 The renal proximal tubule (PT) is a major site for a complete tissue renin-angiotensin system (RAS) and produces endogenous angiotensin II (ANG II). The present studies demonstrate autocrine RAS feedback in a line of origin-defective SV40 plasmid transform ... Full text Link to item Cite

Molecular mechanisms of glucose action on angiotensinogen gene expression in rat proximal tubular cells.

Journal Article Kidney Int · February 1999 BACKGROUND: Clinical studies have shown that the angiotensin-converting enzyme (ACE) inhibitors or angiotensin II (Ang II) receptor antagonists decrease proteinuria and slow the progression of nephropathy in diabetes, indicating that Ang II plays an import ... Full text Link to item Cite

Synergistic effect of dexamethasone and isoproterenol on the expression of angiotensinogen in immortalized rat proximal tubular cells.

Journal Article Kidney Int · February 1998 To investigate whether the expression of angiotensinogen (ANG) in rat kidney proximal tubules is stimulated by dexamethasone and isoproterenol, immortalized rat proximal tubular cells (IRPTC) were cultured in a monolayer. Immunoreactive rat ANG (IR-rANG) i ... Full text Link to item Cite

Immortalized rat proximal tubule cells produce membrane bound and soluble megalin.

Journal Article Kidney Int · February 1998 Megalin (gp330), a glycoprotein receptor found on renal proximal tubule cells and several other epithelial cells, is deduced to be a type I integral membrane protein, but may also exist as a cell surface form lacking a cytoplasmic domain. Furthermore, solu ... Full text Link to item Cite

Drug prescribing in rural health facilities in China: Implications for service quality and cost

Journal Article Tropical Doctor · 1998 Excessive and inappropriate drug prescribing practices in developing countries expose patients to health risks and raise health costs. In China, the transition to a market-oriented economy has been accompanied by a largely unregulated market for drugs and ... Cite

The changing role of township health centres

Journal Article IDS Bulletin · January 1, 1997 Township health centres occupy a key position in the Chinese rural health system, providing a range of curative and preventive services and undertaking administrative duties. Through a case study of health centres in one poor rural county, this article sho ... Cite

Drug prescribing in rural health facilities in China: Implications for service quality and cost

Journal Article IDS Bulletin · January 1, 1997 This article reports the results of a survey of drug prescriptions by facilities in poor rural areas. They found excessive and inappropriate prescribing of drugs, which exposed patients to the risk of ineffective treatment and adverse side effects, and con ... Cite

Bringing basic health care to the rural poor.

Journal Article World Health Forum · 1996 In the 1960s and 1970s China provided a good model for financing and delivering rural health services in developing countries. Since the implementation of economic reforms which began in the 1980s, however, health services in poor areas have been showing s ... Link to item Cite

Cooperative medical schemes in contemporary rural China.

Journal Article Soc Sci Med · October 1995 Improvements in rural health care in China in the 1950s, 1960s and 1970s were largely due to the development of cooperative medical schemes (CMSs) and the establishment of a three-tier rural health network. Since the economic reforms were instituted in the ... Full text Link to item Cite

NF-kappa B and transcriptional control of renal epithelial-inducible nitric oxide synthase.

Journal Article Kidney Int · September 1995 Expression of the inducible isoform of nitric oxide synthase (iNOS) is subject to strict tissue specific transcriptional control. Recently, the NF-kappa B/Rel family of transcription factors, and particularly c-rel, was shown to mediate bacterial lipopolys ... Full text Link to item Cite

Trichomonas vaginalis and cervical cancer. A prospective study in China.

Journal Article Ann Epidemiol · July 1995 The relationship between Trichomonas vaginalis infection and cervical cancer was investigated prospectively in a cohort of 16,797 women aged 25 years or more who were followed from 1974 to 1985 within the framework of a cervical screening program in Jingan ... Full text Link to item Cite

Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.

Journal Article J Clin Invest · May 1995 An inducible nitric oxide synthase has recently been described in proximal tubule epithelium. To investigate the effects of proximal tubule NO on Na+/K(+)-ATPase, we induced NO production in mouse proximal tubule epithelial cells by treatment with lipopoly ... Full text Link to item Cite

Temperature-sensitive SV40 immortalized rat proximal tubule cell line has functional renin-angiotensin system.

Journal Article Am J Physiol · March 1995 Immortalized rat proximal tubule cell (IRPTC) lines should be useful for investigation of proximal tubule (PT) regulation and function but previously have been unavailable. We now report the establishment and characterization of an immortalized transformed ... Full text Link to item Cite

Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules.

Journal Article J Am Soc Nephrol · February 1995 The synthesis of nitric oxide by proximal tubule-inducible nitric oxide synthase requires tetrahydrobiopterin as a cofactor. To determine whether tetrahydrobiopterin synthesis is required for nitric oxide production, nitrite release by mouse proximal tubul ... Full text Link to item Cite

The financing and organization of health services in poor rural China: a case study in Donglan County.

Journal Article Int J Health Plann Manage · 1995 The socio-economic reforms launched in China in the late 1970s led to rapid economic growth and, with it, health sector resources expanded rapidly. The rural health services have benefited from the policies of economic reform, but not in an optimal way, pa ... Full text Link to item Cite

Reform of the Chinese health care financing system.

Journal Article Health Policy · 1995 The radical changes which have been taken place in the Chinese economy since the late 1970s have influenced the health sector and the health care financing system. A rapid increase in medical care costs in the last decade has placed a heavy financial burde ... Full text Link to item Cite

Distribution and function of cardiac angiotensin AT1- and AT2-receptor subtypes in hypertrophied rat hearts.

Journal Article Am J Physiol · August 1994 To determine distribution and function of cardiac angiotensin (ANG) II receptor AT1 and AT2 subtypes in left ventricular (LV) hypertrophy (LVH), ANG II (10(-8) M) was infused into isolated rat hearts with hypertrophy from aortic banding and into sham-opera ... Full text Link to item Cite

Renin and angiotensinogen mRNA expression in the kidneys of rats subjected to long-term bile duct ligation.

Journal Article Hepatology · June 1994 Activation of antinatriuretic systems such as the renin-angiotensin system, is of major importance in the pathogenesis of sodium retention in cirrhosis. In this study, we studied the intrarenal renin-angiotensin system by measuring renin and angiotensinoge ... Link to item Cite

Angiotensin converting enzyme in renal ontogeny: hypothesis for multiple roles.

Journal Article Pediatr Nephrol · December 1993 Angiotensin converting enzyme (ACE) has multiple effects both as the enzyme which cleaves angiotensin II from angiotensin I and as that which breaks down bradykinin. The present study examines ACE mRNA and protein expression in the rat kidney during develo ... Full text Link to item Cite

Regulation of intrarenal and circulating renin-angiotensin systems in severe heart failure in the rat.

Journal Article Cardiovasc Res · May 1993 OBJECTIVE: Activation of the intrarenal renin-angiotensin system may contribute to the pathophysiology of heart failure by accelerating the generation of angiotensin II at local sites within the kidneys. Activation of the local intrarenal renin-angiotensin ... Full text Link to item Cite

Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts.

Journal Article Circulation · April 1993 BACKGROUND: The intracardiac conversion rate of angiotensin (Ang) I to Ang II and the expression of angiotensin converting enzyme (ACE) mRNA are amplified in rat hearts with left ventricular hypertrophy (LVH). To examine whether the accelerated intracardia ... Full text Link to item Cite

Financing health care in rural China: preliminary report of a nationwide study.

Journal Article Soc Sci Med · February 1993 One unforeseen consequence of the change from collective to household production in rural China has been that the financial basis of the rural health services has been eroded. The majority of peasants now pay for health care on a fee-for-service basis. A m ... Full text Link to item Cite

Molecular biology techniques and their applicability to the study of diabetes and hypertension: the renin-angiotensin system as an example.

Journal Article J Am Soc Nephrol · October 1992 Recently developed molecular biology techniques lend themselves to the study of both normal physiology and pathophysiology. This review discusses a number of such techniques and their applicability to the study of diabetes and hypertension with the renin-a ... Full text Link to item Cite

Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure.

Journal Article J Clin Invest · October 1992 The intrarenal renin-angiotensin system (RAS) may contribute to the pathophysiology of heart failure by the generation of angiotensin II at local sites within the kidneys. Angiotensin II may directly influence renal hemodynamics, glomerular contractility, ... Full text Link to item Cite

Characterization of nuclear angiotensin-II-binding sites in rat liver and comparison with plasma membrane receptors.

Journal Article Endocrinology · July 1992 Although the action of angiotensin-II (Ang-II) is believed to be mediated by a transmembrane signal transduction mechanism, accumulating evidence suggests that Ang-II may also have a direct nuclear action. We have characterized the nuclear Ang-II-binding s ... Full text Link to item Cite

Molecular mechanism of tissue-specific regulation of mouse renin gene expression by cAMP. Identification of an inhibitory protein that binds nuclear transcriptional factor.

Journal Article J Biol Chem · August 25, 1991 Renin gene expression in the mouse kidney and submandibular gland (SMG) are differentially regulated by cAMP. In this study, we examined the potential molecular mechanism responsible for this tissue-specific regulation. 32P end-labeled synthetic oligonucle ... Link to item Cite

Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.

Journal Article J Clin Invest · December 1990 We compared the activity and physiologic effects of cardiac angiotensin converting enzyme (ACE) using isovolumic hearts from male Wistar rats with left ventricular hypertrophy due to chronic experimental aortic stenosis and from control rats. In response t ... Full text Link to item Cite

Endothelial renin-angiotensin pathway. Adrenergic regulation of angiotensin secretion.

Journal Article Circ Res · January 1990 Cultured bovine aortic endothelial cells (BAECs) express the complete renin-angiotensin system and secrete angiotensins. In this study, we examined the adrenergic influence on the secretion of angiotensins from BAECs. Angiotensins were determined by high-p ... Full text Link to item Cite

Partial purification of a prorenin activating enzyme in the aortic wall.

Journal Article Clin Exp Hypertens A · 1988 The presence of a prorenin activating enzyme in the blood vessel wall may have important physiological implications. The putative enzyme may be involved with the endogenous production of active renin (a key enzyme in the vascular renin angiotensin system) ... Full text Link to item Cite

Effects of rice or wheat residue retention on the quality of milled japonica rice in a rice–wheat rotation system in China

Journal Article Crop Journal · January 1, 1970 In rice–wheat rotation systems, crop straw is usually retained in the field at land preparation in every, or every other, season. We conducted a 3-year-6-season experiment in the middle–lower Yangtze River Valley to compare the grain qualities of rice unde ... Full text Cite