Book · January 1, 2016
The latest edition of this text provides a practical reference for physicians and other health care providers caring for patients with gastrointestinal bleeding. Similar to the previous edition, this volume addresses common problems associated with gastroi ...
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Chapter · January 1, 2016
Gastrointestinal hemorrhage caused by gastroesophageal laceration was first reported by Quincke in 1879; however, the association with retching and vomiting was described by Mallory and Weiss in 1929 (Mallory and Weiss, Am J Med Sci, 178:506-514, 1929; Qui ...
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Journal ArticleWorld J Gastrointest Endosc · March 16, 2015
AIM: To evaluate the success rates of performing therapy utilizing a rotational assisted enteroscopy device in endoscopic retrograde cholangiopancreatography (ERCP) in surgically altered anatomy patients. METHODS: Between June 1, 2009 and November 8, 2012, ...
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Journal ArticleAnesth Analg · July 2014
BACKGROUND: Moderate sedation is routinely performed in patients undergoing minor therapeutic and diagnostic procedures outside the operating room. The level of sedation is often monitored by sedation nurses using clinical criteria, such as sedation scores ...
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Journal ArticleWorld J Gastroenterol · December 14, 2013
AIM: To compare efficacy and complications of partially covered self-expandable metal stent (pcSEMS) to plastic stent (PS) in patients treated for malignant, infrahilar biliary obstruction. METHODS: Multicenter prospective randomized clinical trial with tr ...
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Journal ArticleAnn Surg · February 2013
OBJECTIVE: The objective of this study was to compare the effectiveness, morbidity, and mortality associated with endoscopic ampullectomy (EA) and surgical ampullectomy (SA). BACKGROUND: The proposed management of benign ampullary lesions includes local re ...
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Journal ArticleGastroenterol Res Pract · 2013
Background and Study Aims. Endoscopic placement of self-expanding metal stents (SEMSs) is indicated for palliation of inoperable malignant biliary obstruction. A fully covered biliary SEMS (WallFlex Biliary RX Boston Scientific, Natick, USA) was assessed f ...
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Journal ArticleJ Vasc Interv Radiol · November 2012
PURPOSE: To report short-term results of empiric transcatheter embolization for patients with advanced malignancy and gastrointestinal (GI) hemorrhage directly from a tumor invading the GI tract wall. MATERIALS AND METHODS: Between 2005 and 2011, 37 mesent ...
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Journal ArticleJOP · September 10, 2012
CONTEXT: Animal studies have demonstrated a role for substance P binding to neurokinin-1 receptor in the pathogenesis of acute pancreatitis. OBJECTIVE: Our aim was to assess the efficacy of a neurokinin-1 receptor antagonist (aprepitant) at preventing post ...
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Journal ArticleGastroenterology Res · April 2012
BACKGROUND: Stent related occlusion and migration remains a problem despite attempts to improve stent design over this time period. Flanged polyethylene plastic stents (FPS) remains the stent of choice in most centers. Early failure of stents placed for ma ...
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Journal ArticlePancreas · May 2011
OBJECTIVES: This study aimed to evaluate whether synthetic secretin is effective in reducing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis. METHODS: This is a single academic medical center, prospective, randomized, double-blind, ...
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Chapter · December 1, 2010
Mallory and Weiss first described gastroesophageal tears causing gastrointestinal bleeding in 15 alcoholic patients in 1929 [1]. Since this time, longitudinal mucosal lacerations, associated with forceful retching, has become a well-known cause of upper ga ...
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Book · December 1, 2010
The diagnosis and management of gastrointestinal bleeding is multidisciplinary by nature involving surgeons, gastroenterologists and radiologists. Due to various pathologies, it involves upper gut, lower gut and occult bleeding. Gastrointestinal Bleeding: ...
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Journal ArticleSurg Endosc · September 2009
BACKGROUND: There is debate about whether intraoperative cholangiography (IOC) should be performed routinely or selectively during laparoscopic cholecystectomy (LC) in patients with suspected choledocholithiasis. The timing of endoscopic retrograde cholang ...
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Journal ArticleSurg Endosc · January 2009
BACKGROUND: There is debate as to whether recurrent biliary complications are more common in patients who do not have elective cholecystectomy after endoscopic retrograde cholangiopancreatography (ERCP) management of common bile duct (CBD) stones. The aim ...
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Journal ArticleAm J Infect Control · October 2008
We have developed an automated surveillance system to detect bloodstream infection (BSI) occurring after endoscopic retrograde cholangiopancreatography (ERCP). We retrospectively applied this automated surveillance tool to all patients who underwent ERCP a ...
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Journal ArticleGastrointest Endosc · July 2008
BACKGROUND: The management strategies for Barrett's esophagus (BE) that contains high-grade dysplasia (HGD) include intensive endoscopic surveillance, photodynamic therapy, thermal ablation, EMR, and esophagectomy. OBJECTIVE: To assess the safety and effec ...
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Journal ArticleWorld J Gastroenterol · December 21, 2007
Endoscopic retrograde cholangiopancreatography (ERCP) is a useful tool in the evaluation and management of acute pancreatitis. This review will focus on the role of ERCP in specific causes of acute pancreatitis, including microlithiasis and gallstone disea ...
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Journal ArticleTechniques in Gastrointestinal Endoscopy · April 1, 2007
Endoscopic management of choledocholithiasis by the gastroenterologist at endoscopic retrograde cholangiopancreatography has become the standard of care and, to a large degree, routine in most endoscopic units. Large common bile duct (CBD) stones or CBD st ...
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Journal ArticleGastrointest Endosc · June 2006
BACKGROUND: Diagnosing pancreatic cancer by EUS-FNA is a potentially appealing alternative to percutaneous biopsy. AIM: To compare EUS-FNA with CT or US-guided FNA for diagnosing pancreatic cancer. DESIGN: Single center, prospective, randomized, cross-over ...
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Journal ArticleDig Liver Dis · January 2006
BACKGROUND: Despite advances in imaging modalities, preoperative diagnosis of pancreatic cystic lesions remains difficult. AIM: To assess the accuracy of endoscopic ultrasound and computer tomography to preoperatively distinguish benign from potentially ma ...
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Journal ArticleAm J Gastroenterol · November 2005
OBJECTIVES: We hypothesized that early intervention in patients with lower gastrointestinal bleeding (LGIB) would improve outcomes and therefore conducted a prospective randomized study comparing urgent colonoscopy to standard care. METHODS: Consecutive pa ...
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Journal ArticleJOP · March 10, 2005
CONTEXT: Pancreatic stents may be placed during therapeutic ERCP for a variety of indications. One such indication is to prophylax against the development of pancreatitis following sphincterotomy of the minor papilla in patients with recurrent acute pancre ...
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Journal ArticleAnn Surg Oncol · March 2005
BACKGROUND: Neoadjuvant (preoperative) chemoradiotherapy (CRT) for pancreatic cancer offers theoretical advantages over the standard approach of surgery followed by adjuvant CRT. We hypothesized that histological responses to CRT would be significant progn ...
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Journal ArticleEndoscopy · August 2004
BACKGROUND AND STUDY AIMS: It is still difficult to differentiate reliably between benign and malignant biliary tract lesions. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has added to the diagnostic power of EUS for other gastrointestinal ...
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Journal ArticleDig Liver Dis · June 2004
BACKGROUND: It has been suggested that preoperative biliary drainage increases the risk of infectious complications of pancreaticoduodenectomy. AIMS: The aim of this study was to assess complications related to biliary stents/drains and postoperative morbi ...
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Journal ArticleAnn Surg Oncol · June 2004
BACKGROUND: This study aimed to define PDS characteristics that predict malignancy and would thus invoke further diagnostic evaluation or aggressive treatment. METHODS: 355 cases of PDS were diagnosed by ERCP during a 7-year period at a single institution. ...
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Journal ArticleJOP · May 2004
CONTEXT: Pancreas divisum has been associated with recurrent acute pancreatitis, chronic abdominal pain without elevated pancreatic enzymes, and chronic pancreatitis. Prior studies suggest that endoscopic minor papillotomy benefits certain symptomatic panc ...
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Journal ArticleJ Clin Gastroenterol · March 2004
During upper gastrointestinal endoscopy, topical oropharyngeal anesthesia with lidocaine and/or benzocaine is used routinely by many endodscopists. Although such a practice is usually safe, there have been a number of reports of methemoglobinemia induced b ...
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Journal ArticleJ Am Coll Surg · August 2003
BACKGROUND: Standard treatment for acute cholecystitis is cholecystectomy, but some patients are at high risk for immediate surgery. Percutaneous cholecystostomy might be the procedure of choice in this group. We reviewed the experience of percutaneous cho ...
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Journal ArticleGastrointest Endosc · June 2003
BACKGROUND: The industry standard since 1990 for self-expanding biliary metallic stents has been the Wallstent. In 1998 the Spiral Z-stent was released. This randomized trial compared the Z-stent with the Wallstent in the treatment of malignant biliary obs ...
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Journal ArticleEndoscopy · April 2003
BACKGROUND AND STUDY AIMS: Small-bowel enteroscopy (SBE) is frequently used to examine patients suspected of small-bowel disease. Unfortunately, the diagnostic yield varies widely, from 13 % to 78 % of cases. This disparity may be in part attributable to t ...
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Journal ArticleCan J Gastroenterol · April 2003
UNLABELLED: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with primary sclerosing cholangitis (PSC) can be a challenging and sometimes gratifying opportunity for therapeutic intervention. Although there often appears to be initial radio ...
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Journal ArticleTechniques in Gastrointestinal Endoscopy · January 1, 2003
Endoscopic sphincterotomy (ES) has been performed for 30 years and is the therapeutic procedure of choice for management of choledocholithiasis, cholangitis, biliary pancreatitis, and other biliary and pancreatic problems. Sphincterotomy is commonly perfor ...
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Journal ArticleCan J Gastroenterol · January 2003
Pain is the dominant clinical problem in patients with chronic pancreatitis. It can be due to pseudocysts, as well as strictures and stones in the pancreatic ducts. Most experts agree that obstruction could cause increased pressure within the main pancreat ...
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Journal ArticleCan J Gastroenterol · December 2002
Featured Publication
BACKGROUND: Serum amylase and lipase levels are widely used as markers of pancreatic inflammation. However, it would seem that mild elevations of amylase and lipase rarely predict significant pancreatic pathology. Pancreatic imaging tests are expensive. Th ...
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Journal ArticleEndoscopy · April 2002
Featured Publication
BACKGROUND AND STUDY AIMS: Perforations during endoscopic retrograde cholangiopancreatography (ERCP) are rare, and the management of these perforations is variable, with some patients requiring immediate surgery and others only conservative management. We ...
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Journal ArticleAnn Surg Oncol · December 2001
BACKGROUND: The use of neoadjuvant (preoperative) chemoradiotherapy (CRT) for pancreatic cancer has been advocated for its potential ability to optimize patient selection for surgical resection and to downstage locally advanced tumors. This article reports ...
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Journal ArticleJ Gastrointest Surg · 2001
Neoadjuvant chemoradiation therapy is used at many institutions for treatment of localized adenocarcinoma of the pancreas. Accurate staging before neoadjuvant therapy identifies patients with distant metastatic disease, and restaging after neoadjuvant ther ...
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Journal ArticleAliment Pharmacol Ther · December 2000
BACKGROUND: Biologically derived porcine secretin has been used as a diagnostic agent in clinical gastrointestinal practice for many years. Pure synthetic porcine secretin is now available for investigational clinical use. AIM: To compare the pharmacology ...
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Journal ArticleAJR Am J Roentgenol · February 2000
OBJECTIVE: We evaluated the feasibility and image quality of a new noninvasive biliary imaging technique: helical CT cholangiography with three-dimensional volume rendering using an oral biliary contrast agent. SUBJECTS AND METHODS: Nineteen subjects inclu ...
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Journal ArticleGastrointest Endosc · October 1999
BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) plays an important role in the management of bile leaks after cholecystectomy. Although most leaks occur from the cystic duct stump, clinically significant leakage from accessory bile ducts ...
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Journal ArticleAm J Gastroenterol · April 1999
Two cases of endoscopic band ligation as lone therapy for Dieulafoy's lesions are presented. Neither patient has experienced further gastrointestinal bleeding; one patient has been followed for 27 months. Endoscopic band ligation is an alternative and attr ...
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Journal ArticleGastrointest Endosc · February 1999
BACKGROUND: Percutaneous biliary drainage is an established alternative to ERCP for managing bile duct obstruction. Although generally safe and effective, percutaneous drainage has its risks and is technically more difficult in patients with nondilated bil ...
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Journal ArticleAm J Gastroenterol · January 1999
We describe the unusual case of a patient who developed recurrent right upper quadrant pain 25 yr after cholecystectomy. A cystic lesion containing a calculus was identified on transabdominal ultrasound, initially suggesting the possibility of gallbladder ...
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Journal ArticleAJR Am J Roentgenol · December 1998
OBJECTIVE: The purpose of this study was to investigate the role of positron emission tomography (PET) with 18F-fluorodeoxyglucose (FDG) in differentiating benign from malignant disease in patients with possible pancreatic malignancy. SUBJECTS AND METHODS: ...
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Journal ArticleAm J Gastroenterol · December 1998
Common hepatic duct obstruction secondary to an impacted cystic duct stone is commonly referred to as the Mirizzi syndrome. Mirizzi syndrome is an uncommon cause of obstructive jaundice and can be mimicked by several other rare conditions. We describe a pa ...
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Journal ArticleGastrointestinal Endoscopy · December 1, 1998
There is considerable debate regarding the optimal management of pancreatic necrosis (PN). The timing and utility of endoscopic retrograde cholangiopancreatograms (ERCP) in the subset of acute pancreatitis who have PN is unclear. Objectives: It To determin ...
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ConferenceGastrointestinal Endoscopy · December 1, 1998
Background: Retrograde surgical drainage is the treatment of choice for relieving incapacitating abdominal pain in patients (pts) with chronic pancreatitis (CP) and pancreatic duct (PD) dilatation. Lateral pancreaticojejunostomy (PJEJ) - the so-called modi ...
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Journal ArticleGastrointestinal Endoscopy · December 1, 1998
Background: Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) are useful techniques in the evaluation of patients (pts) with biliary and pancreatic diseases. Pts undergoing EUS are commonly undergoing ERCP as well. The u ...
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Journal ArticleGastrointestinal Endoscopy · December 1, 1998
ERCP in patients with primary sclerosing cholangitis (PSC) can be a challenging and occasionally gratifying opportunity for therapeutic intervention. Although there often appears to be initial radiological improvement, the benefit as measured by serial est ...
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Journal ArticleGastrointestinal Endoscopy · December 1, 1998
Background: The abrupt termination of the ventral pancreatic duct due to local pathology is sometimes mistaken for pancreas divisum. This so called "pseudodivisum" anatomy has implications for patient management, especially the timely identification of mal ...
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Journal ArticleGastrointestinal Endoscopy · December 1, 1998
Patients with PSC can have intrahepatic or extrahepatic biliary strictures, or both, resulting in cholestasis and cholangitis. ERCP is commonly performed in the hope of locating a dominant extrahepatic or hilar stricture amenable to endoscopic therapy. The ...
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Journal ArticleGastrointestinal Endoscopy · December 1, 1998
Background: The management of patients with complex biliary pathology often requires the combined efforts of biliary endoscopists and vascular radiologists. Percutaneous access with placement of stents or drains is often needed if endoscopic retrograde cho ...
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Journal ArticleGastrointestinal Endoscopy · December 1, 1998
ERCP is commonly performed in patients with known PSC in hopes of delineating dominant strictures amenable to endoscopic therapy. Knowledge of certain factors may be important in predicting successful management of these patients. Objective: To determine w ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1997
Background: Cholangitis, severe gallstone pancreatitis, and bile duct injuries are indications for urgent endoscopic retrograde cholangio-pancreatography (ERCP). Performing ERCP "out of hours" has its problems as support personnel may not be available and ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1997
Background: Postoperative bile leak is a common indication for ERCP after cholecystectomy. Aberrant or "accessory" bile duct leaks (ABDL) are difficult to recognize; appropriate treatment is often delayed. The purpose of this study is to review the managem ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1997
Background: The safety and efficacy of GA for ERCP has not been studied systematically. We describe our referral center experience with the use of GA for ERCP. Methods: Patients undergoing ERCP with GA were identified in our computerized database; their me ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1997
In the era of LC, ERCP is the diagnostic and therapeutic modality of choice for post-up bile leaks. The existing algorithm has to be modified when leaks (a) fail to resolve with stenting or sphx or (b) cannot be localized by ERCP. The following algorithm r ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1997
Background: ERCP has an expected success rate of greater than 90% but is technically difficult in patients with post-surgical anatomy. It is especially challenging after Roux-en-Y gastrojejunostomy, as the papilla has to be reached through the Roux limb. W ...
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Journal ArticleAnn Intern Med · December 15, 1996
BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) is a technically demanding procedure that can cause substantial complications. Competence in performing ERCP and the learning curve for achieving competence are poorly understood. OBJECTIVE: ...
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Journal ArticleAm J Gastroenterol · November 1996
A 30-yr-old female with a carcinoid tumor of the ampulla of Vater is discussed. This rare tumor presented in an unusual fashion with isolated pancreatitis in the absence of cholestasis. The correct diagnosis was made preoperatively by endoscopic retrograde ...
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Journal ArticleGastrointest Endosc · November 1996
BACKGROUND: Conventional esophageal prosthesis placement has been associated with a 6% to 8% perforation rate and numerous postplacement complications. Expandable esophageal stents have been developed to preclude the above but there are few studies that ha ...
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ConferenceGastrointestinal Endoscopy · 1996
Background: Endoscopic therapy is an accepted treatment for pain in chronic pancreatitis, in addition to traditional management. However, guidelines for selecting treatment options have yet to be established. This study addresses 2 questions: (a) which pat ...
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ConferenceGastrointestinal Endoscopy · 1996
INTRODUCTION: Case reports and small series have indicated that endoscopic therapy for pancreatic fistulae (PF) may be successful. This series reviews the experience with PF at a tertiary care referral center. METHODS: A retrospective review of the DUMC en ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1996
INTRODUCTION: The etiology of post ERCP pancreatitis is unknown, although numerous associations have been postulated. Identification of specific risk factors may lead to insights in etiology and prevention of this common complications. METHODS: Data on 6,0 ...
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ConferenceGastrointestinal Endoscopy · 1996
Background: Despite its distinct advantages and overall safety, LC has its complications, including biliary leak. The role of ERCP in the diagnosis and treatment of post-LC bile leaks is still evolving. We review a tertiary referral center experience of ER ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1996
Introduction: Magnetic Resonance Cholangiopancreatography (MRCP) is a novel application of MRI which may replace diagnostic ERCP in many cases. The indications for and diagnostic yield of MRCP remain to be elucidated. We performed a comparison of MRCP and ...
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ConferenceGastrointestinal Endoscopy · 1996
Background: Our previously published algorithm for management of PP1 assumed that (a) recurrence rates after percutaneous management are related to the presence of pancreatic duct (PD) obstruction or PP communication with the PD and (b) surgical management ...
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Journal ArticleGastrointestinal Endoscopy · January 1, 1996
Aim: To evaluate the number of ERCPs gastroenterology fellows should perform to achieve competency. Methods: From July 1993 to June 1995 consecutive ERCPs performed by fellows were graded on a standardized evaluation form. Success in specific technical com ...
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Journal ArticleGastrointest Endosc · December 1995
BACKGROUND: Proximal migration of a biliary stent is an uncommon event, but its management can present a technical challenge to the therapeutic endoscopist. METHODS: We reviewed the methods that have been used for retrieval of proximally migrated biliary s ...
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Journal ArticleAm J Gastroenterol · March 1995
Pneumomediastinum is a rare complication of endoscopy that usually indicates free peritoneal or retroperitoneal perforation. We report an unusual case of self-limiting pneumomediastinum after endoscopic sphincterotomy in which there was no radiological evi ...
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Journal ArticleAnn Surg · May 1993
OBJECTIVE: A total of 50 major bile duct injuries after laparoscopic cholecystectomy were managed by the Duke University Hepatobiliary Service from 1990-1992. The management of these complex cases is reviewed. SUMMARY BACKGROUND DATA: Laparoscopic cholecys ...
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