Scholars@Duke
Suresh Kumar Agarwal Jr.

Suresh Kumar Agarwal Jr.

Professor of Surgery
Trauma, Acute, and Critical Care Surgery

Selected Publications

Reducing Missed Doses of VTE Prophylaxis.

Journal Article JAMA Surg · December 1, 2025 Full text Link to item Cite

State-level COVID-19 lockdown stringency associated with increases in motor-vehicle mortality rates.

Journal Article J Safety Res · December 2025 BACKGROUND: Motor-vehicle collision fatalities increased dramatically during the COVID-19 pandemic in the United States, but significant variation existed between states. The objective of this study was to examine the relationship between state-level COVID ... Full text Link to item Cite

Dads also matter: paternal and maternal factors associated with infant injury mortality.

Journal Article Inj Prev · November 27, 2025 BACKGROUND: Despite advances in injury prevention, trauma remains a leading cause of infant mortality in the USA. This study sought to compare maternal characteristics with paternal risk factors for injury-related mortality for infants. METHODS: Data were ... Full text Link to item Cite

Asian American Representation in Surgical Training in the United States.

Journal Article J Surg Res · November 2025 INTRODUCTION: Asians are considered an over-represented minority in medicine, making up 7% of the US national population but 17.1% of active physicians. However, representation trends are different across surgical specialties, and many surgical residency p ... Full text Link to item Cite

Original scientific paper in-hospital and post-discharge outcomes with autologous versus prosthetic repair of traumatic abdominal vascular injuries: a 10-year review of the PROOVIT registry.

Journal Article Am J Surg · October 2025 PURPOSE: Abdominal vascular injury (AVI) often coincides with bowel injury and abdominal contamination. Prosthetic materials may be necessary for vascular reconstruction, but outcomes are poorly understood. We examined outcomes in patients undergoing autol ... Full text Link to item Cite

Factors Influencing End-of-Life Decisions in Cancer Patients After Traumatic Injuries.

Journal Article J Surg Res · August 2025 INTRODUCTION: Severe traumatic injuries are frequently associated with poor outcomes, and withdrawal of life-sustaining treatment (WLST) after traumatic brain injury is common. However, the association between WLST and pre-existing cancer in all trauma pat ... Full text Link to item Cite

Pediatric Versus Adult Blunt Cerebrovascular Injuries: Patients Characteristics, Management, and Outcomes.

Journal Article Ann Vasc Surg · July 2025 BACKGROUND: Blunt cerebrovascular injury (BCVI) management in children currently follows guidelines developed for adults, with limited data on their efficacy in the pediatric population. This study aimed to explore injury features in the pediatric populati ... Full text Link to item Cite

Trauma, Gender, and End-of-Life Care: A Propensity-Matched Cohort Study Analyzing Disparities in Withdrawal of Life Support.

Journal Article J Surg Res · July 2025 INTRODUCTION: Men are known to have more severe injuries at younger ages compared to women. However, the relationship between gender and other sociodemographic factors in the context of end-of-life care after traumatic injuries is not well understood. METH ... Full text Link to item Cite

Relation of Malnutrition on Septic Older Adults in Emergency Gastrointestinal Surgery: A Modified Global Leadership Initiative on Malnutrition Analysis.

Journal Article J Surg Res · July 2025 INTRODUCTION: Malnutrition in older adults has significant ramifications for surgical outcomes. The incidence of malnutrition is up to 30% in emergent gastrointestinal surgery (EGS). This study aims to investigate malnutrition's correlation on outcomes of ... Full text Link to item Cite

In-Hospital Risk Factors for Reintervention and Amputation in Femoral Arterial Trauma.

Journal Article J Surg Res · July 2025 INTRODUCTION: Known risk factors for surgical reintervention of traumatic femoral artery injuries include thrombosis of vascular reconstruction, kinking of anastomosis, and iatrogenic injury. The literature regarding possible in-hospital risk factors is sp ... Full text Link to item Cite

Exploratory cluster analysis of IL2Ra and associated biomarkers and complications after blunt chest trauma.

Journal Article J Trauma Acute Care Surg · June 1, 2025 BACKGROUND: Rib fractures compromise approximately 40% of all fractures in the United States. Despite their prevalence, the relationship between rib fractures, solid organ injuries, and immune responses remains poorly understood. This exploratory study inv ... Full text Link to item Cite

Penalizing underage alcohol use is associated with lower mortality for young drivers: Use/lose laws and their association with motor vehicle collision mortality.

Journal Article J Trauma Acute Care Surg · February 1, 2025 BACKGROUND: Motor vehicle collisions (MVC) continue to be a leading cause of mortality for youth in the United States. Since 2010, seven states have revoked mandatory laws that suspended licenses for underage alcohol use, also known as use/lose laws. This ... Full text Link to item Cite

Age-Related Vulnerability to Malnutrition-Related Mortality: Younger Patients are at Risk.

Journal Article J Surg Res · February 2025 INTRODUCTION: Malnutrition among older adults continues to be a prevalent health concern. While literature has highlighted an increased risk of malnutrition mortality for adults older than 65 y, the age threshold at which malnutrition effects survival and ... Full text Link to item Cite

Lower Extremity Penetrating Trauma Care Associated With Race and Income in the United States of America.

Journal Article J Surg Res · February 2025 INTRODUCTION: For lower extremity penetrating traumas (LEPT), the impact of race and insurance status, as a surrogate of socioeconomic status, is still not fully elucidated. This study aims to explore the relationship between these variables and the likeli ... Full text Link to item Cite

Disparities in educational attainment and assault mortalities among Asian Americans in the USA, 2009-2021.

Journal Article Inj Prev · December 9, 2024 BACKGROUND: In 2021, a spike in Asian American hate crimes resurged discussion on Asian health disparities. This study describes the association between education and assault among Asian Americans and their subgroups. METHODS: This cross-sectional study us ... Full text Link to item Cite

Child Firearm-Related Homicide and Suicide by State Legislation in the US (2009 to 2020).

Journal Article J Am Coll Surg · December 1, 2024 BACKGROUND: Firearms are the leading cause of death among US children and adolescents. This study evaluates whether state gun laws are associated with firearm suicides and homicides in children. STUDY DESIGN: This is a cross-sectional database study compar ... Full text Link to item Cite

Platelet-rich plasma enhances rib fracture strength and callus formation in vivo.

Journal Article J Trauma Acute Care Surg · December 1, 2024 BACKGROUND: Rib fractures are a common traumatic injury affecting more than 350,000 patients a year. Early stabilization has shown to be effective in reducing pulmonary complications. Platelet-rich plasma (PRP) is a growth factor-rich blood product known t ... Full text Link to item Cite

Potential risks of nonoperative management of appendicitis in high-risk patients.

Journal Article Surgery · December 2024 INTRODUCTION: The popularity of nonoperative management for acute appendicitis is based on the untested assumption that it offers a lower risk alternative to surgery in patients who are at high risk for morbidity and mortality with appendectomy. We hypothe ... Full text Link to item Cite

Enteral and Parenteral Nutrition Timing in eICU Collaborative Research Database by Race: A Retrospective Observational Study.

Journal Article J Surg Res · December 2024 INTRODUCTION: Racial and ethnic disparities in malnutrition are well-known, but it is unknown if there are disparities in early nutrition delivery for intensive care unit (ICU) patients, which is associated with better outcomes. We investigated the timing ... Full text Link to item Cite

A Multifactorial Analysis of Trauma Outcomes: Comorbidities, Race, and Socioeconomic Status.

Journal Article J Surg Res · December 2024 INTRODUCTION: Trauma patients with comorbid conditions are known to have poorer outcomes. We hypothesize that these outcomes are further influenced by race or ethnicity and socioeconomic status. METHODS: We queried patient records in the Trauma Quality Imp ... Full text Link to item Cite

Age-Neutral Surgical Stabilization of Rib Fractures: Breaking the Ageism Barrier.

Journal Article J Surg Res · October 2024 INTRODUCTION: Surgical stabilization of rib fractures (SSRF) is associated with lower rates of mortality and fewer complications. This study evaluates whether the decision to undergo SSRF is associated with age, race, ethnicity, and insurance status and as ... Full text Link to item Cite

Predictive Energy Equations Inaccurately Estimate Metabolic Demands of Older Adult Trauma Patients.

Journal Article J Surg Res · October 2024 INTRODUCTION: Suboptimal nutrition promotes unfavorable outcomes in trauma patients, particularly among those aged 60 and over. While many institutions employ predictive energy equations to determine patients' energy requirements, mounting evidence shows t ... Full text Link to item Cite

The Earlier the Better: Surgical Stabilization of Rib Fractures Associated With Improved Outcomes.

Journal Article J Surg Res · October 2024 INTRODUCTION: Surgical stabilization of rib fractures (SSRF) has been associated with lower rates of mortality and fewer respiratory complications. This study sought to evaluate the association between SSRF timing and patient outcomes. METHODS: This retros ... Full text Link to item Cite

Firearm Ownership: A Key Factor to Consider in Firearm Suicide Deaths in Children, Despite State Gun Laws.

Journal Article J Surg Res · September 2024 INTRODUCTION: Firearm-related suicides among children present a significant public health concern and a tragic loss of young lives. This study explores the relationship between firearm-related suicides, gun ownership, and state-specific gun laws. METHODS: ... Full text Link to item Cite

The Ethical Obligation to Treat Infectious Patients: A Systematic Review of Reasons.

Journal Article Clin Infect Dis · August 16, 2024 During pandemics, healthcare providers struggle with balancing obligations to self, family, and patients. While HIV/AIDS seemed to settle this issue, coronavirus disease 2019 (COVID-19) rekindled debates regarding treatment refusal. We searched MEDLINE, Em ... Full text Link to item Cite

In-Hospital Risk Factors for Reintervention and Amputation in Brachial Arterial Trauma.

Journal Article J Surg Res · August 2024 INTRODUCTION: Brachial artery trauma is a rare but potentially devastating injury. There is little data regarding risk factors for reintervention and amputation prevention in this population, as well as anticoagulant (AC) and antiplatelet (AP) regimens and ... Full text Link to item Cite

Outcomes by time-to-OR for penetrating abdominal trauma patients.

Journal Article Am J Emerg Med · May 2024 INTRODUCTION: Time-To-OR is a critical process measure for trauma performance. However, this measure has not consistently demonstrated improvement in outcome. STUDY DESIGN: Using TQIP, we identified facilities by 75th percentile time-to-OR to categorize sl ... Full text Link to item Cite

Systematic Literature Review of Health-Related Quality-of-Life Measures for Caregivers of Older Adult Trauma Patients.

Journal Article J Surg Res · May 2024 INTRODUCTION: As the older adult population increases, hospitals treat more older adults with injuries. After leaving, these patients suffer from decreased mobility and independence, relying on care from others. Family members often assume this responsibil ... Full text Link to item Cite

Racial and ethnic demographics in malnutrition related deaths.

Journal Article Clin Nutr ESPEN · April 2024 BACKGROUND AND AIMS: Currently, 40 million Americans are food insecure. They are forced to skip meals and buy non-nutritious food, leading to health disparities for those of low socioeconomic status. This study aims to investigate relationships between mal ... Full text Link to item Cite

Factors Associated with Discharge to Skilled Nursing Facility Following Gunshot Wounds.

Journal Article J Surg Res · February 2024 INTRODUCTION: Firearm injury is a public health crisis. Most victims are minorities in underserved neighborhoods. Measuring firearm injury by mortality underestimates its impact, as most victims survive to discharge. This study was done to determine if rac ... Full text Link to item Cite

Is nonoperative management of appendicitis safe and effective in multi-morbid patients?

Journal Article Surgery · February 2024 BACKGROUND: The purpose of this study was to (1) compare post-treatment outcomes of operative and nonoperative management of acute appendicitis in multi-morbid patients and (2) evaluate the generalizability of prior clinical trials by determining whether o ... Full text Link to item Cite

The Use of Parenteral Nutrition and Disparities in Its Allocation Following Traumatic Injury.

Journal Article J Surg Res · January 2024 INTRODUCTION: Severe traumatic injury requires rapid and extensive deployment of resources to save the lives of the critically injured. The sequelae of traumatic injuries frequently require extensive intervention obligating patients to a complicated recove ... Full text Link to item Cite

Efficacy of BETTER transitional care intervention for diverse patients with traumatic brain injury and their families: Study protocol of a randomized controlled trial.

Journal Article PLoS One · 2024 OBJECTIVE: The purpose of this study is to examine the efficacy of BETTER (Brain Injury, Education, Training, and Therapy to Enhance Recovery) vs. usual transitional care management among diverse adults with traumatic brain injury (TBI) discharged home fro ... Full text Open Access Link to item Cite

Pain management in trauma: the need for trauma-informed opioid prescribing guidelines.

Journal Article Trauma Surg Acute Care Open · 2024 BACKGROUND/OBJECTIVES: Surgical populations and particularly injury survivors often present with complex trauma that elevates their risk for prolonged opioid use and misuse. Changes in opioid prescribing guidelines during the past several years have yielde ... Full text Link to item Cite

GUIDELINE ADHERENCE IMPROVES RIB FRACTURE PATIENT OUTCOMES

Conference CRITICAL CARE MEDICINE · 2024 Cite

Damage Control Resuscitation in Penetrating Trauma: Rules of the Game

Chapter · January 1, 2024 “One of the most frustrating situations ever encountered by the operating surgeon is an open wound in a patient whose blood will not clot and cannot be made to clot.” In their seminal 1981 description of damage control surgery for exsanguinating trauma pat ... Full text Cite

Injury of the Kidney, Ureter, and Bladder

Chapter · January 1, 2024 Including both blunt and penetrating trauma, renal injuries occur in 0.3-1.2% of all trauma patients, and 15-25% of patients with pelvic fracture incur urologic injury. The American Association for the Surgery of Trauma (AAST) Injury Criteria are used to c ... Full text Cite

Examining Helmet Legislation Variations and Motorcycle Fatality Rates across US States

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2024 Cite

Understanding Perioperative Cardiac Arrest in Pediatric Surgery

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2024 Cite

Unlocking the Puzzle: Exploring Firearm Suicides, Gun Laws, Mental Health Access, and Youth

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2024 Cite

1549: GUIDELINE ADHERENCE IMPROVES RIB FRACTURE PATIENT OUTCOMES

Conference Critical Care Medicine · January 2024 Full text Cite

Current status of research on emergency surgery score in trauma patients: a bibliometric analysis.

Journal Article Transl Pediatr · November 28, 2023 BACKGROUND: The use of a relevant emergency score can provide an accurate assessment of the patient's condition and prognosis. However, the status of related studies remains unclear. The current study analyzed the research status of emergency surgery score ... Full text Link to item Cite

Resuscitative thoracotomy

Chapter · November 3, 2023 Full text Cite

A National Comparison of Volume and Acuity for Adult and Pediatric Trauma: A Trauma Quality Improvement Program Cohort Study.

Journal Article J Surg Res · November 2023 INTRODUCTION: Most injured children receive trauma care outside of a pediatric trauma center. Differences in physiology, dosing, and injury pattern limit extrapolation of adult trauma principles to pediatrics. We compare US trauma center experience with pe ... Full text Link to item Cite

Development of a prospective biliary dashboard to compare performance and surgical cost.

Journal Article Surg Endosc · November 2023 BACKGROUND: Transparency around surgeon level data may align healthcare delivery with quality care for patients. Biliary surgery includes numerous procedures performed by both general surgeons and subspecialists alike. Cholecystectomy is a common surgical ... Full text Link to item Cite

The BETTER Traumatic Brain Injury Transitional Care Intervention: A Feasibility Study.

Journal Article West J Nurs Res · October 2023 This study aimed to investigate the feasibility, acceptability, and clinical outcome measures of BETTER (Brain Injury Education, Training, and Therapy to Enhance Recovery), a culturally tailored traumatic brain injury (TBI) transitional care intervention, ... Full text Link to item Cite

State Firearm Laws and Rate of Assault-Related Firearm Death.

Journal Article J Am Coll Surg · September 1, 2023 BACKGROUND: Studying firearm-related mortality is important to reduce preventable firearm death in the US. This study aims to determine the relationship between firearm laws and assault death with firearms. STUDY DESIGN: This ecologic study used public dat ... Full text Link to item Cite

Factors Associated With Triage Decisions in Older Adult Trauma Patients: Impact on Mortality and Morbidity.

Journal Article J Surg Res · August 2023 INTRODUCTION: As medical advances have significantly increased the life expectancy among older adults, the number of older patients requiring trauma care has risen proportionately. Nevertheless, it is unclear among this growing population which sociodemogr ... Full text Link to item Cite

Prospective, multicenter study of antimicrobial-coated, noncrosslinked, acellular porcine dermal matrix (XenMatrix™ AB Surgical Graft) for hernia repair in all centers for disease control and prevention wound classes: 24-month follow-up cohort.

Journal Article Ann Med Surg (Lond) · May 2023 UNLABELLED: Prospective, multicenter, single-arm study of antimicrobial-coated, noncrosslinked, acellular porcine dermal matrix (AC-PDM) in a cohort involving all centers for disease control and prevention wound classes in ventral/incisional midline hernia ... Full text Link to item Cite

Non-surgical management and analgesia strategies for older adults with multiple rib fractures: A systematic review, meta-analysis, and joint practice management guideline from the Eastern Association for the Surgery of Trauma and the Chest Wall Injury Society.

Journal Article J Trauma Acute Care Surg · March 1, 2023 BACKGROUND: Chest wall injury in older adults is a significant cause of morbidity and mortality. Optimal nonsurgical management strategies for these patients have not been fully defined regarding level of care, incentive spirometry (IS), noninvasive positi ... Full text Link to item Cite

Insurance Status and Ethnicity Impact Health Disparities in Rates of Advance Directives in Trauma.

Journal Article Am Surg · January 2023 INTRODUCTION: Advanced directives (ADs) provide a framework from which families may understand patient's wishes. However, end-of-life planning may not be prioritized by everyone. This analysis aimed to determine what populations have ADs and how they affec ... Full text Link to item Cite

Restrictive Firearm Laws and Firearm-Related Suicide.

Journal Article J Am Coll Surg · January 1, 2023 BACKGROUND: There were 23,854 suicides by firearms in 2017 in the US, accounting for 60% of all gun deaths. Studying firearm-related mortalities is vital for reducing preventable gun deaths. This study aims to determine the association between state-level ... Full text Link to item Cite

Quality care is equitable care: a call to action to link quality to achieving health equity within acute care surgery.

Journal Article Trauma Surg Acute Care Open · 2023 Health equity is defined as the sixth domain of healthcare quality. Understanding health disparities in acute care surgery (defined as trauma surgery, emergency general surgery and surgical critical care) is key to identifying targets that will improve out ... Full text Link to item Cite

Need for Assessment of Older Adult Caregivers; The Silent Secondary Trauma Patient

Conference JOURNAL OF THE AMERICAN GERIATRICS SOCIETY · 2023 Cite

Operative exposure and management of axillary vessel injuries

Chapter · January 1, 2023 Axillary artery injuries are uncommon. At times they are defined as axillo-subclavian injuries. Anatomy is complex. Exposure requires transecting the pectoralis minor tendon. They have associated brachial plexus injuries. ... Full text Cite

Penetrating carotid artery injuries

Chapter · January 1, 2023 Carotid arterial injuries are the most difficult and certainly the most immediate life-threatening injuries found in penetrating neck trauma. Their propensity to bleed actively and potentially occlude the airway makes surgical intervention very challenging ... Full text Cite

Subclavian vessel injuries: Difficult anatomy and difficult territory

Chapter · January 1, 2023 Subclavian vessel injuries are uncommon and quite difficult to approach and manage. Most are due to penetrating injuries and require rapid surgical interventions, as they usually present in shock with exsanguinating hemorrhage. Their surgical exposure usua ... Full text Cite

Brachial vessel injuries: High morbidity and low mortality injuries

Chapter · January 1, 2023 These are among the most common vascular injuries seen in an urban trauma center. They are sometimes associated with median and ulnar nerve injuries. This vessel is much more amenable to surgical exposure. Injuries may require dissection below the elbow. T ... Full text Cite

Exercise Attenuates Septic Inflammatory Response in Murine Model

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2023 Cite

Exercise Attenuates Septic Inflammatory Response in Murine Model

Conference JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS · 2023 Cite

Tracheostomy

Chapter · December 15, 2022 Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. ... Link to item Cite

Racial Differences in Firearms Used and Autopsies Following Gun Deaths Exist.

Journal Article J Surg Res · November 2022 INTRODUCTION: Disparities in gun violence across race are well documented. Studying these disparities is essential to reduce preventable gun deaths. This study evaluates the relationship between sociodemographic factors and firearms used in gun deaths. MAT ... Full text Link to item Cite

Restrictive Firearm Laws Are Associated with Decreased Firearm-Related Suicides

Conference Journal of the American College of Surgeons · November 2022 Full text Cite

Association between spine injury and opioid misuse in a prospective cohort of Level I trauma patients.

Journal Article OTA Int · September 2022 OBJECTIVE: To explore patient and treatment factors explaining the association between spine injury and opioid misuse. DESIGN: Prospective cohort study. SETTING: Level I trauma center in a Midwestern city. PARTICIPANTS: English speaking patients aged 18 to ... Full text Link to item Cite

Underutilization of Acetaminophen in Older Adult Trauma Patients.

Journal Article Am Surg · August 2022 INTRODUCTION: Older adults are more vulnerable to opioid-associated morbidity. The purpose of this study was to determine the frequency and timing of acetaminophen and opioid use in the postoperative period. METHODS: Older adult trauma patients (≥65 years) ... Full text Link to item Cite

Trends in Assault Mortalities Among Asian Americans, 2009-2018.

Journal Article J Surg Res · July 2022 INTRODUCTION: As of yet, few studies have described the prevalence or rates of assault mortalities involving Asian victims on a national level. This study aimed to describe yearly trends and regional differences in assault mortalities among Asians. METHODS ... Full text Link to item Cite

Bovine versus porcine acellular dermal matrix for abdominal wall herniorrhaphy or bridging.

Journal Article Eur J Trauma Emerg Surg · June 2022 BACKGROUND: The management of complicated ventral hernias (CVH), namely ventral hernias in actively or recently infected/contaminated operative fields, and open abdomens in which the native fascia cannot be primarily reapproximated, pose a surgical challen ... Full text Link to item Cite

Incidence and Diagnostic Challenges of Bowel Ischemia after Continuous-flow Left Ventricular Assist Device Therapy.

Journal Article ASAIO J · May 1, 2022 Long-term continuous-flow left ventricular assist device (CFLVAD) therapy is limited by complications. Compared with stroke and renal dysfunction, post-CFLVAD bowel ischemia is poorly characterized. Adult patients who underwent first-time durable CFLVAD im ... Full text Link to item Cite

Design, methods, and baseline characteristics of the Brain Injury Education, Training, and Therapy to Enhance Recovery (BETTER) feasibility study: a transitional care intervention for younger adult patients with traumatic brain injury and caregivers.

Journal Article Curr Med Res Opin · May 2022 OBJECTIVES: We developed a patient- and family-centered traumatic brain injury (TBI) transitional care intervention, called BETTER (Brain Injury Education, Training, and Therapy to Enhance Recovery), to improve quality of life (via SF-36) of younger TBI pa ... Full text Link to item Cite

Revision of the AAST grading scale for acute cholecystitis with comparison to physiologic measures of severity.

Journal Article J Trauma Acute Care Surg · April 1, 2022 BACKGROUND: Grading systems for acute cholecystitis are essential to compare outcomes, improve quality, and advance research. The American Association for the Surgery of Trauma (AAST) grading system for acute cholecystitis was only moderately discriminant ... Full text Link to item Cite

Screening in Trauma for Opioid Misuse Prevention (STOMP): Results from a prospective cohort of victims of traumatic injury.

Journal Article Drug Alcohol Depend · March 1, 2022 BACKGROUND: Traumatic injury frequently requires opioid analgesia to manage pain and avoid catastrophic complications. Risk screening for opioid misuse and the development of use disorder remains uninvestigated. METHODS: Participants were Trauma/Orthopedic ... Full text Link to item Cite

Trends in Location of Death Among Older Adult Americans After Falls.

Journal Article Gerontol Geriatr Med · 2022 Introduction: Fall-related mortality is increasing among older adults, yet trends and changes in the location of fall-attributed deaths are unknown; additionally, potential disparities are understudied. Methods: To assess trends/factors associated with pla ... Full text Link to item Cite

Traumatic injuries to the trachea and bronchi: a narrative review.

Journal Article Mediastinum · 2022 OBJECTIVE: In this narrative review, we aim to provide a definition of traumatic tracheo-bronchial injuries as well as an approach to their diagnosis and management, including operative and non-operative strategies. BACKGROUND: Traumatic tracheo-bronchial ... Full text Link to item Cite

Antibiotic prophylaxis for tube thoracostomy placement in trauma: a practice management guideline from the Eastern Association for the Surgery of Trauma.

Journal Article Trauma Surg Acute Care Open · 2022 BACKGROUND: Antibiotic prophylaxis is routinely administered for most operative procedures, but their utility for certain bedside procedures remains controversial. We performed a systematic review and meta-analysis and developed evidence-based recommendati ... Full text Link to item Cite

Role of Nutrition in the Elderly Surgical Patient – Review of the Literature and Current Recommendations

Journal Article Current Geriatrics Reports · December 1, 2021 Purpose of Review: Poor nutritional status is common among inpatients, and particularly so among surgical patients. The problem is even more pronounced among elderly surgical patients, with age itself being an independent risk factor for malnutrition. With ... Full text Cite

Massive Transfusion Protocol Predictive Modeling in the Modern Electronic Medical Record.

Journal Article Ann Surg Open · December 2021 OBJECTIVES: Integrate a predictive model for massive transfusion protocol (MTP) activation and delivery in the electronic medical record (EMR) using prospectively gathered data; externally validate the model and assess the accuracy and precision of the mod ... Full text Link to item Cite

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

Journal Article Br J Surg · September 27, 2021 BACKGROUND: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. METHODS: The primary outcome was the number needed to vaccinate (NNV) to prev ... Full text Link to item Cite

Comparison of Bariatric Protocols in Laparoscopic Sleeve Gastrectomy: A Retrospective Analysis on Patient Outcomes

Journal Article Bariatric Surgical Practice and Patient Care · September 1, 2021 Background: More than 250,000 laparoscopic sleeve gastrectomy (LSG) are performed annually accounting for about 61.4% of all bariatric procedures. The national average cost for LSG ranges between $15,000 and 33,000 with an estimated economic impact of $7.5 ... Full text Cite

Acute Respiratory Distress Syndrome (ARDS) after trauma: Improving incidence, but increasing mortality.

Journal Article J Crit Care · August 2021 PURPOSE: Acute Respiratory Distress Syndrome (ARDS) is an infrequent, yet morbid inflammatory complication in injury victims. With the current project we sought to estimate trends in incidence, determine outcomes, and identify risk factors for ARDS and rel ... Full text Link to item Cite

Evaluation of malnutrition via modified GLIM criteria for in patients undergoing emergent gastrointestinal surgery.

Journal Article Clin Nutr · March 2021 BACKGROUND: Malnutrition remains a critical public health issue in the US, particularly in surgery where perioperative malnutrition is commonly underdiagnosed and undertreated. In 2016, the Global Leadership Initiative on Malnutrition (GLIM) proposed a set ... Full text Link to item Cite

Histone Deacetylase 3 Associates With Key Regulators of NFκB Signaling in Lung Epithelial Cells Under Stimulation With LPS.

Conference · 2021 AbstractIntroduction: Histone Deacetylase 3 (HDAC3) is a Class I member of the histone deacetylase family that is recruited to nuclear enhancers. HDAC3 is located within the cell nucleus, where it con ... Full text Cite

IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages.

Journal Article PLoS One · 2021 INTRODUCTION: Anti-inflammatory cytokine IL-10 suppresses pro-inflammatory IL-12b expression after Lipopolysaccharide (LPS) stimulation in colonic macrophages, as part of the innate immunity Toll-Like Receptor (TLR)-NF-κB activation system. This homeostati ... Full text Link to item Cite

Contemporary management of Axillo-subclavian Arterial Injuries Using Data from the AAST PROOVIT Registry

Journal Article Journal of Endovascular Resuscitation and Trauma Management · January 1, 2021 Background: Endovascular repair has emerged as a viable repair option for axillo-subclavian arterial injuries in select patients; however, further study of contemporary outcomes is warranted. Methods: The American Association for the Surgery of Trauma (AAS ... Full text Cite

The Impact of Nonsteroidal Anti-inflammatory Drugs on Older Adult Trauma Patients With Hip Fractures.

Journal Article J Surg Res · November 2020 BACKGROUND: Nonsteroidal anti-inflammatory drug (NSAID) use is frequently recommended for multimodal analgesia to reduce opioid use. We hypothesized that increased NSAID utilization will decrease opioid requirements without leading to significant complicat ... Full text Link to item Cite

Discrepancy in Endoscopic Reporting and Lack of Standardization for the Diagnosis of Hiatal Hernia

Journal Article Journal of the American College of Surgeons · October 2020 Full text Cite

"I'm Leaving": Factors That Impact Against Medical Advice Disposition Post-Trauma.

Journal Article J Emerg Med · April 2020 BACKGROUND: Discharge against medical advice (AMA) is an important, yet understudied, aspect of health care-particularly in trauma populations. AMA discharges result in increased mortality, increased readmission rates, and higher health care costs. OBJECTI ... Full text Link to item Cite

Histone Deacetylase 7 Inhibition in a Murine Model of Gram-Negative Pneumonia-Induced Acute Lung Injury.

Journal Article Shock · March 2020 BACKGROUND: Pulmonary infections remain the most common cause of Acute Respiratory Distress Syndrome (ARDS), a pulmonary inflammatory disease with high mortality, for which no targeted therapy currently exists. We have previously demonstrated an ameliorate ... Full text Link to item Cite

Surgical management of peptic ulcer disease.

Journal Article Curr Probl Surg · February 2020 Full text Link to item Cite

In Brief

Journal Article Current Problems in Surgery · February 1, 2020 Full text Cite

Race and Insurance Status as Predictors of Bicycle Trauma Outcome in Adults.

Journal Article J Surg Res · January 2020 BACKGROUND: Race and insurance status have been shown to predict outcomes in pediatric bicycle traumas. It is unknown how these factors influence outcomes in adult bicycle traumas. This study aims to evaluate the association, if any, between race and insur ... Full text Link to item Cite

Acetaminophen, Underutilized in Older Adult Trauma Patients

Conference ANESTHESIA AND ANALGESIA · 2020 Cite

Are Octogenarians and Older Adult Trauma Patients Equivalent

Conference Journal of the American College of Surgeons · October 2019 Full text Cite

Bovine vs Porcine Acellular Dermal Matrix for Abdominal Wall Herniorrhaphy or Bridging

Conference Journal of the American College of Surgeons · October 2019 Full text Cite

Optimizing venetoclax dose in combination with low intensive therapies in elderly patients with newly diagnosed acute myeloid leukemia: An exposure-response analysis.

Journal Article Hematol Oncol · October 2019 The objective of this research was to characterize the venetoclax exposure-efficacy and exposure-safety relationships and determine its optimal dose in elderly patients with newly diagnosed acute myeloid leukemia (AML) receiving venetoclax in combination w ... Full text Link to item Cite

The Impact of Race and Socioeconomic Status on Treatment and Outcomes of Blunt Splenic Injury.

Journal Article J Surg Res · August 2019 BACKGROUND: Racial, ethnic, and socioeconomic disparities have been shown to exist in trauma patients. Management of blunt splenic injuries (BSIs) can include splenectomy, embolization, or nonoperative management. This study assesses the effect of race and ... Full text Link to item Cite

Pharmacokinetics of the BCL-2 Inhibitor Venetoclax in Subjects with Hepatic Impairment.

Journal Article Clin Pharmacokinet · August 2019 INTRODUCTION: Venetoclax is a selective B cell lymphoma-2 inhibitor. It is approved for treatment of chronic lymphocytic leukemia and is being investigated for other hematological malignancies. Venetoclax is predominantly eliminated by the liver; therefore ... Full text Link to item Cite

Higher mortality in pediatric and adult trauma patients with traumatic coagulopathy, using age-adjusted diagnostic criteria.

Journal Article Surgery · June 2019 BACKGROUND: Acute traumatic coagulopathy has been described in adult trauma patients. Acute traumatic coagulopathy may be associated with higher mortality and morbidity in pediatric trauma patients. We aimed to (1) compare acute traumatic coagulopathy inci ... Full text Link to item Cite

What's in a Name? Provider Perception of Injured John Doe Patients.

Journal Article J Surg Res · June 2019 BACKGROUND: We previously demonstrated that unidentified aliased patients, John Doe's (DOEs), are one of the highest risk and most medically fragile populations of injured patients. Aliasing can result in misplaced information and confusion that must be ov ... Full text Link to item Cite

Venetoclax Combined With Low-Dose Cytarabine for Previously Untreated Patients With Acute Myeloid Leukemia: Results From a Phase Ib/II Study.

Journal Article J Clin Oncol · May 20, 2019 PURPOSE: Effective treatment options are limited for patients with acute myeloid leukemia (AML) who cannot tolerate intensive chemotherapy. An international phase Ib/II study evaluated the safety and preliminary efficacy of venetoclax, a selective B-cell l ... Full text Link to item Cite

Socioeconomic Status Affects Outcomes After Severity-Stratified Traumatic Brain Injury.

Journal Article J Surg Res · March 2019 BACKGROUND: Socioeconomic status (SES) and race have been shown to increase the incidence of being afflicted by a traumatic brain injury (TBI) resulting in worse posthospitalization outcomes. The goal of this study was to determine the effect disparities h ... Full text Link to item Cite

Utility of fiber-optic bronchoscopy in pulmonary infections among abdominal solid-organ transplant patients: A comprehensive review.

Journal Article Respir Med · January 2019 Pulmonary infections are frequent complications in abdominal solid-organ transplantation (aSOT) which may threaten patient and allograft survival. Accurate diagnosis and treatment of pulmonary infections in this population can be challenging. Immunosuppres ... Full text Link to item Cite

A meta-analysis of higher-risk myelodysplastic syndrome trials to evaluate the relationship between short-term endpoints and overall survival

Journal Article Journal of Cancer · January 1, 2019 Background: The objective of this work was to evaluate the relationship between the response rates and median overall survival (OS) in higher-risk myelodysplastic syndrome (HR-MDS) to determine whether response rates could be used as predictors of median O ... Full text Cite

Acute Surgical Decision-Making in Abdominal Trauma Is Not Altered by Race or Socioeconomic Status.

Journal Article Am Surg · December 1, 2018 Two main procedures are performed on patients suffering from colonic perforation, diverting colostomy and primary tissue repair. We investigated patient race, ethnicity, and socioeconomic status (SES) that predicted surgical outcomes after blunt or penetra ... Link to item Cite

Patient-Centered Outcome Spectrum: An Evidence-based Framework to Aid in Shared Decision-making.

Journal Article Ann Surg · December 2018 OBJECTIVE: Our objective was to develop an alternate construct for reporting anticipated outcomes after emergency general surgery (EGS) that presents risk in terms of a composite measure. BACKGROUND: Currently available prediction tools generate risk outpu ... Full text Link to item Cite

Effect of Azithromycin on Venetoclax Pharmacokinetics in Healthy Volunteers: Implications for Dosing Venetoclax with P-gp Inhibitors.

Journal Article Adv Ther · November 2018 INTRODUCTION: Venetoclax, a substrate of cytochrome P450 (CYP) 3A and P-glycoprotein (P-gp), is approved for the treatment of patients with chronic lymphocytic leukemia who have received at least one prior therapy. This study evaluated the effect of azithr ... Full text Link to item Cite

Effects of Obesity on Penetrating Trauma

Conference Journal of the American College of Surgeons · October 2018 Full text Cite

Predicting Which Patients Will Leave Against Medical Advice

Conference Journal of the American College of Surgeons · October 2018 Full text Cite

Indications for rib fixation

Chapter · September 3, 2018 There are no clear, absolute, and universally accepted indications or contraindications for operative rib fixation. Furthermore, although the majority of experts believe patients benefit most from early operative fixation, there is no consensus agreement r ... Full text Cite

Rib Fracture Location Should Be Evaluated When Predicting Morbidity and Mortality in Trauma Patients.

Conference Am Surg · September 1, 2018 Rib fractures represent up to 55 per cent of thoracic blunt traumatic injuries and lead to significant mortality and morbidity. The aim of this study is to determine whether not only number but also the location of rib fractures can be used to risk stratif ... Link to item Cite

Venetoclax, bendamustine, and rituximab in patients with relapsed or refractory NHL: a phase Ib dose-finding study.

Journal Article Ann Oncol · September 1, 2018 BACKGROUND: Venetoclax is a selective, potent inhibitor of the anti-apoptotic B-cell leukemia/lymphoma-2 protein approved for treatment of chronic lymphocytic leukemia. We conducted a dose-finding study of venetoclax in combination with bendamustine-rituxi ... Full text Link to item Cite

Barriers to Hospice Care in Trauma Patients: The Disparities in End-of-Life Care.

Journal Article Am J Hosp Palliat Care · August 2018 INTRODUCTION: End-of-life and palliative care are important aspects of trauma care and are not well defined. This analysis evaluates the racial and socioeconomic disparities in terms of utilization of hospice services for critically ill trauma patients. ME ... Full text Link to item Cite

Socioeconomics affecting quality outcomes in Asian trauma patients within the United States.

Journal Article J Surg Res · August 2018 INTRODUCTION: Asian-Americans and Pacific Islanders are often considered as a uniform group when examining race in health outcomes. However, the generally favorable economic outcomes in this group belie significant socioeconomic variance between its hetero ... Full text Link to item Cite

Transplant Critical Care: Is there a Need for Sub-specialized Units? - A Perspective.

Journal Article J Crit Care Med (Targu Mures) · July 2018 The critical care involved in solid-organ transplantation (SOT) is complex. Pre-, intra- and post-transplant care can significantly impact both - patients' ability to undergo SOT and their peri-operative morbidity and mortality. Much of the care necessary ... Full text Link to item Cite

Pharmacokinetics of the BCL-2 Inhibitor Venetoclax in Healthy Chinese Subjects.

Journal Article Clin Pharmacol Drug Dev · May 2018 Venetoclax has been approved in the United States, Europe, Canada, and Australia for appropriate patients with difficult-to-treat chronic lymphocytic leukemia (CLL). The objective of this phase 1 study was to evaluate the pharmacokinetics of venetoclax in ... Full text Link to item Cite

Venetoclax for patients with chronic lymphocytic leukemia who progressed during or after idelalisib therapy.

Journal Article Blood · April 12, 2018 B-cell receptor pathway inhibitors (BCRis) have transformed treatment of chronic lymphocytic leukemia (CLL); however, the efficacy of therapies for patients whose disease is refractory to/relapses after (R/R) BCRis is unknown. Venetoclax is a selective, or ... Full text Link to item Cite

Socioeconomic disparities in the thoracic trauma population.

Journal Article J Surg Res · April 2018 BACKGROUND: Health-care disparities based on socioeconomic status have been well documented in the trauma literature; however, there is a paucity of data on how these factors affect outcomes in patients experiencing severe thoracic trauma. This study aims ... Full text Link to item Cite

Venetoclax as Targeted Therapy for Relapsed/Refractory Multiple Myeloma

Conference BRITISH JOURNAL OF HAEMATOLOGY · April 1, 2018 Link to item Cite

Thoracoscopic, minimally invasive rib fixation after trauma

Journal Article Trauma United Kingdom · April 1, 2018 Rib fractures and flail chest are associated with significant morbidity and mortality. Operative rib fixation has been shown to improve patient outcomes. In an attempt to decrease postoperative pain and wound infection rates, we performed rib fixation usin ... Full text Cite

Indications for surgical stabilization of rib fractures in patients without flail chest: surveyed opinions of members of the Chest Wall Injury Society.

Journal Article Int Orthop · February 2018 PURPOSE: There are currently no evidence-based indications for surgical stabilization of rib fractures (SSRF) in patients without flail chest. The purpose of this survey was to identify patients for whom there is relative equipoise (operative vs. non-opera ... Full text Link to item Cite

Pre-simulation orientation for medical trainees: An approach to decrease anxiety and improve confidence and performance.

Journal Article Am J Surg · February 2018 BACKGROUND: We assessed the effect of basic orientation to the simulation environment on anxiety, confidence, and clinical decision making. METHODS: Twenty-four graduating medical students participated in a two-week surgery preparatory curriculum, includin ... Full text Link to item Cite

Race, insurance status, and traumatic brain injury outcomes before and after enactment of the Affordable Care Act.

Journal Article Surgery · February 2018 BACKGROUND: The Affordable Care Act aims to improve patient outcomes. Race/ethnicity and insurance status impact outcomes after traumatic brain injury. We sought to gauge the Affordable Care Act's effect on outcomes after traumatic brain injury, as graded ... Full text Link to item Cite

Why saying what you mean matters: An analysis of trauma team communication.

Journal Article Am J Surg · February 2018 BACKGROUND: We hypothesized that team communication with unmatched grammatical form and communicative intent (mixed mode communication) would correlate with worse trauma teamwork. METHODS: Interdisciplinary trauma simulations were conducted. Team performan ... Full text Link to item Cite

Identifying Nontechnical Skill Deficits in Trainees Through Interdisciplinary Trauma Simulation.

Journal Article J Surg Educ · 2018 OBJECTIVE: The goal of this study was to investigate nontechnical skills in a simulated trauma setting both before and after a debriefing session in order to better understand areas to target for the development of educational interventions. DESIGN: Wilcox ... Full text Link to item Cite

Screening in Trauma for Opioid Misuse Prevention (STOMP): study protocol for the development of an opioid risk screening tool for victims of injury.

Journal Article Addict Sci Clin Pract · December 4, 2017 BACKGROUND: Opioid addiction and overdose are epidemic in the U.S. Victims of traumatic injury are at greater than average risk for opioid misuse and related complications. Potential risk screens and preventive interventions in this clinical population rem ... Full text Link to item Cite

The capacity of ICD-10-CM/PCS to characterize surgical care.

Journal Article J Trauma Acute Care Surg · November 2017 Full text Link to item Cite

Predicting Liver Failure in Patients Undergoing Partial Hepatectomy

Conference Journal of the American College of Surgeons · October 2017 Full text Cite

Improving Patient-Centered Transitional Care after Complex Abdominal Surgery.

Journal Article J Am Coll Surg · August 2017 BACKGROUND: Poor-quality transitions of care from hospital to home contribute to high rates of readmission after complex abdominal surgery. The Coordinated Transitional Care (C-TraC) program improved readmission rates in medical patients, but evidence-base ... Full text Link to item Cite

Surgical management of pancreatic necrosis: A practice management guideline from the Eastern Association for the Surgery of Trauma.

Conference J Trauma Acute Care Surg · August 2017 BACKGROUND: Pancreatic or peripancreatic tissue necrosis confers substantial morbidity and mortality. New modalities have created a wide variation in approaches and timing of interventions for necrotizing pancreatitis. As acute care surgery evolves, its pr ... Full text Link to item Cite

Number of rib fractures thresholds independently predict worse outcomes in older patients with blunt trauma.

Conference Surgery · April 2017 BACKGROUND: There have been conflicting reports regarding whether the number of rib fractures sustained in blunt trauma is associated independently with worse patient outcomes. We sought to investigate this risk-adjusted relationship among the lesser-studi ... Full text Link to item Cite

Patterns of Facial Fractures and Protective Device Use in Motor Vehicle Collisions From 2007 to 2012.

Journal Article JAMA Facial Plast Surg · December 1, 2016 IMPORTANCE: Facial fractures after motor vehicle collisions are a significant source of facial trauma in patients seen at trauma centers. With recent changes in use of seat belts and advances in airbag technology, new patterns in the incidence of facial fr ... Full text Link to item Cite

Insurance status and race affect treatment and outcome of traumatic brain injury.

Journal Article J Surg Res · October 2016 BACKGROUND: There is increasing evidence that race and socioeconomic factors affect patient outcomes after traumatic brain injury (TBI). Our goal was to assess the effect of race, ethnicity and insurance status on hospital length of stay, procedures perfor ... Full text Link to item Cite

Nonoperative Management Is as Effective as Immediate Splenectomy for Adult Patients with High-Grade Blunt Splenic Injury.

Journal Article J Am Coll Surg · August 2016 BACKGROUND: The comparative effectiveness of nonoperative management (NOM) vs immediate splenectomy (IS) for hemodynamically stable adult patients with grade IV or V blunt splenic injury (BSI) has not been clearly established in the literature. STUDY DESIG ... Full text Link to item Cite

Which Complications Matter Most? Prioritizing Quality Improvement in Emergency General Surgery.

Journal Article J Am Coll Surg · April 2016 BACKGROUND: Because preoperative risk factor modification is generally not possible in the emergency setting, complication prevention represents an important focus for quality improvement in emergency general surgery (EGS). The objective of our study was t ... Full text Link to item Cite

Multicenter validation of American Association for the Surgery of Trauma grading system for acute colonic diverticulitis and its use for emergency general surgery quality improvement program.

Conference J Trauma Acute Care Surg · March 2016 BACKGROUND: The American Association for the Surgery of Trauma (AAST) has developed a new grading system for uniform description of anatomic severity of emergency general surgery (EGS) diseases, ranging from Grade I (mild) to Grade V (severe). The purpose ... Full text Link to item Cite

Predictors of mortality, hospital utilization, and the role of race in outcomes in head and neck trauma.

Journal Article Oral Surg Oral Med Oral Pathol Oral Radiol · January 2016 OBJECTIVE: A retrospective cross-sectional analysis was undertaken to determine the impact of race and insurance status on trauma outcomes in patients admitted to a Level I trauma center following head and neck fractures. STUDY DESIGN: Putative predictive ... Full text Link to item Cite

Cumulative Cardiovascular Polypharmacy Is Associated With the Risk of Acute Kidney Injury in Elderly Patients.

Journal Article Medicine (Baltimore) · August 2015 Polypharmacy is common in the elderly due to multimorbidity and interventions. However, the temporal association between polypharmacy and renal outcomes is rarely addressed and recognized. We investigated the association between cardiovascular (CV) polypha ... Full text Link to item Cite

ICD-9-CM and ICD-10-CM mapping of the AAST Emergency General Surgery disease severity grading systems: Conceptual approach, limitations, and recommendations for the future.

Journal Article J Trauma Acute Care Surg · May 2015 The American Association for the Surgery of Trauma (AAST) recently established a grading system for uniform reporting of anatomic severity of several emergency general surgery (EGS) diseases. There are five grades of severity for each disease, ranging from ... Full text Link to item Cite

Application of a uniform anatomic grading system to measure disease severity in eight emergency general surgical illnesses.

Journal Article J Trauma Acute Care Surg · November 2014 BACKGROUND: Emergent general surgical diseases encompass a broad spectrum of anatomy and pathophysiology, creating challenges for outcomes assessment, research, and surgical training. The goal of this study was to measure anatomic disease severity for eigh ... Full text Link to item Cite

A composite index for predicting readmission following emergency general surgery.

Journal Article J Trauma Acute Care Surg · June 2014 BACKGROUND: Preventable readmission has become a national focus. It is clear that surgical patients present specific challenges to those interested in preventing readmission. Little is known about this outcome in the emergent population. We are interested ... Full text Link to item Cite

Mechanosignaling in bone health, trauma and inflammation.

Journal Article Antioxid Redox Signal · February 20, 2014 SIGNIFICANCE: Mechanosignaling is vital for maintaining the structural integrity of bone under physiologic conditions. These signals activate and suppress multiple signaling cascades regulating bone formation and resorption. Understanding these pathways is ... Full text Link to item Cite

Acid–base physiology

Chapter · January 1, 2014 The body is able to maintain an arterial pH in a very narrow range due to intracellular and extracellular mechanisms that are able to correct for large physiologic perturbations. The most common mechanisms for compensation of pH abnormalities is through th ... Full text Cite

Successful nonoperative management of the most severe blunt renal injuries: a multicenter study of the research consortium of New England Centers for Trauma.

Journal Article JAMA Surg · October 2013 IMPORTANCE: Severe renal injuries after blunt trauma cause diagnostic and therapeutic challenges for the treating clinicians. The need for an operative vs a nonoperative approach is debated. OBJECTIVE: To determine the rate, causes, predictors, and consequ ... Full text Link to item Cite

Emergency general surgery: definition and estimated burden of disease.

Journal Article J Trauma Acute Care Surg · April 2013 BACKGROUND: Acute care surgery encompasses trauma, surgical critical care, and emergency general surgery (EGS). While the first two components are well defined, the scope of EGS practice remains unclear. This article describes the work of the American Asso ... Full text Link to item Cite

Adult intussusception secondary to colorectal cancer in a young man: a case report.

Journal Article J Emerg Med · December 2012 BACKGROUND: The occurrence of adult intussusception from colorectal cancer in a 27-year-old man is quite uncommon. OBJECTIVES: To raise awareness of the incidence of intussusception in adults, to educate others about the protean manifestations and high ass ... Full text Link to item Cite

Evidence-based guidelines are equivalent to a liberal computed tomography scan protocol for initial patient evaluation but are associated with decreased computed tomography scan use, cost, and radiation exposure.

Journal Article J Trauma Acute Care Surg · September 2012 BACKGROUND: We hypothesized that trauma patient evaluations using evidence-based treatment guidelines (evidence-based group [EBG]), which include serial examinations and limited computed tomography (CT) scans in an established trauma center, would be assoc ... Full text Link to item Cite

Intensive care unit experience of haemopoietic stem cell transplant patients.

Journal Article Intern Med J · July 2012 BACKGROUND: Previous research at our institution (1988-1998) established an intensive care unit (ICU) and hospital mortality between 70% and 80% in haemopoietic stem cell transplant (HSCT) patients requiring ICU admission. AIMS: This study explored mortali ... Full text Link to item Cite

Injury-induced changes in liver specific transcription factors HNF-1α and HNF-4α.

Journal Article J Surg Res · June 15, 2012 BACKGROUND: The hepatic acute phase response(APR) is an organ-specific response to a diverse array of insults and is largely under transcriptional control. Liver-specific transcription factors, hepatic nuclear factors (HNFs)-1α and 4α play important roles ... Full text Link to item Cite

Successful nonoperative management of the most severe blunt liver injuries: a multicenter study of the research consortium of new England centers for trauma.

Journal Article Arch Surg · May 2012 HYPOTHESIS: Grade 4 and grade 5 blunt liver injuries can be safely treated by nonoperative management (NOM). DESIGN: Retrospective case series. SETTING: Eleven level I and level II trauma centers in New England. PATIENTS: Three hundred ninety-three adult p ... Full text Link to item Cite

A massive transfusion protocol incorporating a higher FFP/RBC ratio is associated with decreased use of recombinant activated factor VII in trauma patients.

Journal Article Am J Clin Pathol · April 2012 We implemented a protocol incorporating a higher fresh frozen plasma (FFP)/RBC ratio for the management of trauma patients requiring massive transfusion in 2007. This study aims to identify issues that affected the effective deployment of the massive trans ... Full text Link to item Cite

Chest X-ray after tracheostomy is not necessary unless clinically indicated.

Journal Article World J Surg · February 2012 BACKGROUND: Chest radiography is routinely used post-tracheostomy to evaluate for complications. Often, the chest X-ray findings do not change clinical management. The present study was conducted to evaluate the utility of post-tracheostomy X-rays. METHOD: ... Full text Link to item Cite

Pain as an indication for rib fixation: a bi-institutional pilot study.

Conference J Trauma · December 2011 BACKGROUND: In trauma patients, open reduction and internal fixation of rib fractures remain controversial. We hypothesized that patients who have open reduction and internal fixation of rib fractures would experience less pain compared with controls and t ... Full text Link to item Cite

Decompressive laparotomy for refractory intracranial hypertension after traumatic brain injury.

Journal Article Neurocrit Care · December 2011 BACKGROUND: Intracranial hypertension is a crucial modifiable risk factor for poor outcome after traumatic brain injury (TBI). Limited evidence suggests that decompressive laparotomy may be an effective treatment for refractory ICH in patients who have ele ... Full text Link to item Cite

Use of airway pressure release ventilation is associated with a reduced incidence of ventilator-associated pneumonia in patients with pulmonary contusion.

Journal Article J Trauma · March 2011 BACKGROUND: Past studies suggest that airway pressure release ventilation (APRV) is associated with reduced sedative requirements and increased recruitment of atelectatic lung, two factors that might reduce the risk for ventilator-associated pneumonia (VAP ... Full text Link to item Cite

An articulating tool for endoscopic screw delivery

Journal Article Journal of Medical Devices Transactions of the ASME · February 17, 2011 This paper describes the development of an articulating endoscopic screw driver that can be used to place screws in osteosynthetic plates during thoracoscopic surgery. The device is small enough to be used with a 12 mm trocar sleeve and transmits sufficien ... Full text Cite

Case Report: Successful non-operative management of spontaneous splenic rupture in a patient with babesiosis.

Journal Article World J Emerg Surg · January 20, 2011 BACKGROUND: Babesiosis is a zoonotic disease transmitted by the Ixodes tick species. Infection often results in sub-clinical manifestations; however, patients with this disease can become critically ill. Splenic rupture has been a previously reported compl ... Full text Link to item Cite

Surgical resident perceptions of trauma surgery as a specialty.

Conference Arch Surg · May 2010 HYPOTHESIS: Presenting the opinions of surgical residents about the appeal of trauma surgery as a specialty may influence current reform. DESIGN: Survey study. SETTING: Academic research. PARTICIPANTS: General surgery residents (postgraduate years 1-5 and ... Full text Link to item Cite

Adherence to ventilator-associated pneumonia bundle and incidence of ventilator-associated pneumonia in the surgical intensive care unit.

Journal Article Arch Surg · May 2010 OBJECTIVE: To examine the impact of adherence to a ventilator-associated pneumonia (VAP) bundle on the incidence of VAP in our surgical intensive care units (SICUs). DESIGN: Prospectively collected data were retrospectively examined from our Infection Cont ... Full text Link to item Cite

An articulating tool for endoscopic screw delivery

Journal Article Journal of Medical Devices Transactions of the ASME · January 1, 2010 Full text Cite

The impact of delirium on clinical outcomes in mechanically ventilated surgical and trauma patients.

Journal Article Crit Care Med · June 2009 OBJECTIVE: Previously, delirium has been identified as an independent risk factor for mortality in critically ill medical patients. We undertook this study to examine the relationships among medication usage, delirium, and clinical outcomes in a critically ... Full text Link to item Cite

Is intravenous urography necessary in the assessment of renal duplex system in children?

Journal Article Surgeon · June 2009 OBJECTIVE: Partial or complete duplication of the renal tract may be an incidental finding or may be associated with significant pathology. Accurate assessment is not always easy. This retrospective review was undertaken to determine whether intravenous ur ... Full text Link to item Cite

Discussion

Journal Article Journal of Trauma Injury Infection and Critical Care · December 1, 2008 Full text Cite

Short-term outcomes of splenectomy avoidance in trauma patients.

Conference Am J Surg · August 2008 BACKGROUND: Strategies for splenic preservation for trauma patients have gained acceptance; however, meaningful outcome evaluations have not been performed. To better understand the consequences of managing patients with splenic injuries, the short-term ou ... Full text Link to item Cite

Regulation of chondrocytic gene expression by biomechanical signals.

Journal Article Crit Rev Eukaryot Gene Expr · 2008 Cartilage is a mechanosensitive tissue, which means that it can perceive and respond to biomechanical signals. Despite the known importance of biomechanical signals in the etiopathogenesis of arthritic diseases and their effectiveness in joint restoration, ... Full text Link to item Cite

Increased risk of deep venous thrombosis with endovascular cooling in patients with traumatic head injury.

Journal Article Am Surg · May 2007 Endovascular therapeutic hypothermia has been shown to preserve neurological function and improve outcomes; however, its use and potential complications have not been fully described in patients with traumatic head injuries. We believe that the use of endo ... Link to item Cite

Major hepatic trauma: warm ischemic tolerance of the liver after hemorrhagic shock.

Journal Article J Surg Res · November 2006 BACKGROUND: The management of severe hepatic trauma frequently involves exposing the liver to varying periods of warm ischemia. The ischemic tolerance of the liver, in the setting of hemorrhagic shock (HS) and trauma, is presently unknown. We tested the hy ... Full text Link to item Cite

Teaching surgical decision-making: an interactive, web-based approach.

Conference J Surg Res · July 2006 BACKGROUND: Skillful surgical care demands proper patient assessment and decision-making. These skills are honed through long hours and years of clinical practice. A decrease in work hours is reducing the number of cases managed by medical students and res ... Full text Link to item Cite

Blunt carotid injury

Journal Article Current Treatment Options in Cardiovascular Medicine · January 1, 2006 Blunt carotid injury (BCI) is an uncommon disorder, occurring in trauma patients as a result of cervical hyperextension, hyperflexion, or direct blow. BCI is commonly present in initially asymptomatic patients who subsequently develop devastating thromboem ... Full text Cite

A mobile trauma database with charge capture.

Journal Article J Trauma · November 2005 BACKGROUND: Charge capture plays an important role in every surgical practice. We have developed and merged a custom mobile database (DB) system with our trauma registry (TRACS), to better understand our billing methods, revenue generators, and areas for i ... Full text Link to item Cite

Metastatic melanoma of gastrocolic ligament treated with minimally invasive approach.

Journal Article Surg Endosc · April 1997 A patient with metastatic melanoma of the gastrocolic ligament was rendered clinically tumor free using a minimally invasive procedure. The technique and the rationale for the procedure are reviewed. ... Full text Link to item Cite

Abnormal intraoperative cholangiography. Treatment options and long-term follow-up.

Conference Arch Surg · April 1997 OBJECTIVE: To determine the long-term outcome in patients with filling defects on intraoperative cholangiography. DESIGN: Case series; retrospective review. SETTING: Community teaching hospital. PATIENTS: All patients (n = 872) undergoing cholecystectomy f ... Full text Link to item Cite