Thomas John Cummings

Journal Article Brain Sci · January 30, 2024 Both glioblastoma (GBM) and dementia are devastating diseases with limited treatments that are usually not curative. Having clinically diagnosed dementia with an associated biopsy-proven etiology and a coexisting GBM diagnosis is a rare occurrence. The rel ... Full text Link to item Cite

Melanocytic Nevus of the Superior Conjunctival Fornix: A Case Report.

Journal Article Case Rep Ophthalmol · 2024 INTRODUCTION: Conjunctival nevi are benign tumors that are commonly located at the nasal or temporal limbus and rarely in the fornix or tarsus. We report a case of a patient presenting with a solitary compound cystic nevus of the conjunctival fornix in the ... Full text Link to item Cite

National pilot of entrustable professional activities in pathology residency training.

Journal Article Acad Pathol · 2024 Entrustable professional activities (EPAs) are observable clinical skills and/or procedures that have been introduced into medical education at the student and resident levels in most specialties to determine readiness to advance into residency or independ ... Full text Link to item Cite

Molecular and clinicopathologic characteristics of gliomas with EP300::BCOR fusions.

Journal Article Acta Neuropathol · December 2022 Full text Link to item Cite

Papillary Glioneuronal Tumor With a Novel GPR37L1-PRKCA Fusion.

Journal Article J Neuropathol Exp Neurol · October 26, 2021 Full text Link to item Cite

Multisite Quality Improvement Study of a Patient-Pathologist Consultation Program.

Journal Article Am J Clin Pathol · May 18, 2021 OBJECTIVES: The aim of this multisite quality improvement study was to evaluate patients' experiences with the patient-centered pathology (PCP) consultation program and to determine whether PCP enhanced their care experience. METHODS: Patients were invited ... Full text Link to item Cite

Pituitary thyrotoxicosis presenting as abnormal thyroid function testing during pregnancy: a case report.

Journal Article J Med Case Rep · April 4, 2021 BACKGROUND: Central hyperthyroidism is a rare form of hyperthyroidism caused by thyrotrope pituitary adenomas. It is characterized by elevated thyroid-stimulating hormone alongside high thyroxine and triiodothyronine. Goiter is the most common symptom of c ... Full text Link to item Cite

Autograft-derived spinal cord mass in the cervical spine following transplantation with olfactory mucosa cells for traumatic spinal cord injury: case report.

Journal Article J Neurosurg Spine · February 1, 2021 This study describes a patient with an autograft-derived spinal cord mass following transplantation of olfactory mucosa for treatment of cervical spine injury. The authors report the case of a 35-year-old man who suffered a complete spinal cord injury (SCI ... Full text Link to item Cite

Eosinophilic globules in a classic ependymoma: evidence of a possible secretory role.

Journal Article Ultrastruct Pathol · November 20, 2020 A number of neoplasms of the central nervous system can demonstrate diffuse eosinophilic globules, known to be secretory products of the corresponding cell type, but they have not been a salient feature in descriptions of classic ependymoma. Here, we prese ... Full text Link to item Cite

Post-traumatic superior oblique tendon nodule associated with acquired Brown syndrome.

Journal Article J AAPOS · October 2020 A 67-year-old woman presented with a left hypotropia and eye pain after a traumatic fall. She had multiple left orbital wall fractures and an acquired limitation to elevation in all gazes, worse in adduction, suggestive of Brown syndrome. During strabismus ... Full text Link to item Cite

Heritable spina bifida in sheep: A potential model for fetal repair of myelomeningocele.

Journal Article J Pediatr Surg · March 2020 BACKGROUND/PURPOSE: In 2004, a heritable occurrence of spina bifida was reported in sheep on a farm in the United States. We maintained and characterized the spina bifida phenotype in this flock to assess its potential as an alternative surgical model. MET ... Full text Link to item Cite

Infectious Keratitis in a 23-Year-Old Patient With Netherton Syndrome.

Journal Article JAMA Ophthalmol · February 1, 2020 Full text Link to item Cite

Genomic Profiling of Circulating Tumor DNA From Cerebrospinal Fluid to Guide Clinical Decision Making for Patients With Primary and Metastatic Brain Tumors.

Journal Article Front Neurol · 2020 Despite advances in systemic therapies for solid tumors, the development of brain metastases remains a significant contributor to overall cancer mortality and requires improved methods for diagnosing and treating these lesions. Similarly, the prognosis for ... Full text Link to item Cite

Ectopic Ocular Surface Calcification in Patients With Hypophosphatasia Treated With Asfotase Alfa.

Journal Article Cornea · July 2019 PURPOSE: To assess for ectopic ocular calcification in a series of patients with hypophosphatasia (HPP) treated with asfotase alfa, a recombinant tissue-nonspecific alkaline phosphatase. METHODS: This is a retrospective analysis of subjects enrolled at Duk ... Full text Link to item Cite

Flow cytometry immunophenotyping of vitreous specimens does not contribute to diagnosis of lymphoma without supporting morphologic features.

Journal Article Diagn Cytopathol · April 2019 BACKGROUND: Diagnostic vitrectomy with flow cytometry immunophenotyping (FCI) is being increasingly used as part of screening for diagnostically challenging cases. We aim to evaluate the utility of combined cytopathology and FCI in diagnostic pars plana vi ... Full text Link to item Cite

Comparison of Optical Coherence Tomography With Fundus Photographs, Fluorescein Angiography, and Histopathologic Analysis in Assessing Coats Disease.

Journal Article JAMA Ophthalmol · February 1, 2019 IMPORTANCE: Coats disease is a rare pediatric vitreoretinopathy that can cause devastating visual and anatomic outcomes. OBJECTIVE: To compare optical coherence tomography (OCT) with fundus photographs, fluorescein angiography (FA), and histopathologic fin ... Full text Link to item Cite

Periocular Histiocytoid Carcinoma: Potential Diagnostic Challenges.

Journal Article Ocul Oncol Pathol · February 2019 Cutaneous histiocytoid carcinoma can occur as a primary tumor of the periocular region. Morphologically similar histiocytoid carcinomas arising as primary tumors of the breast have a predilection for orbital metastases. They can occasionally contain region ... Full text Link to item Cite

Cholesterol Crystals in the Anterior Segment in Coats' Disease.

Journal Article Ophthalmol Retina · August 2018 Full text Link to item Cite

Masson's tumor of the pineal region: case report.

Journal Article J Neurosurg · June 2018 Intracranial intravascular papillary endothelial hyperplasia (IPEH), also referred to as Masson's tumor, is a condition that rarely occurs in the nervous system. IPEH most frequently occurs extracranially in the skin of the face, skull, neck, and trunk and ... Full text Link to item Cite

Primary intracranial leiomyoma in an immunocompetent patient.

Journal Article Clin Neuropathol · 2018 Full text Link to item Cite

Pleomorphic adenoma of the lacrimal gland: A review with updates on malignant transformation and molecular genetics

Journal Article Saudi Journal of Ophthalmology · January 1, 2018 Pleomorphic adenoma (benign mixed tumor) is the most common epithelial neoplasm of the lacrimal gland. It is usually a slow growing, well-circumscribed, mass that is identical to its salivary gland counterpart. Patients generally have an excellent prognosi ... Full text Cite

Optic nerve choristoma

Journal Article Saudi Journal of Ophthalmology · January 1, 2018 Full text Cite

Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy.

Journal Article J AAPOS · October 2017 We report a 23-month-old patient presenting with multifocal iris melanoma who underwent plaque brachytherapy with full corneal coverage. The lesion demonstrated several high-risk clinical and histopathologic features associated with iris melanoma in adults ... Full text Link to item Cite

Endodermal Cyst of the Third Nerve in a Child.

Journal Article J Neuroophthalmol · September 2017 Endodermal cysts, also known as neurogenic, neuroenteric, foregut, bronchogenic, respiratory, epithelial, teratomatous, or gastrocytoma cysts, can be found in the central nervous system, predominantly in the subarachnoid space of the cervical and thoracic ... Full text Link to item Cite

Anterior Chamber Angle Invasion of Iridociliary Melanoma.

Journal Article Ophthalmology · June 2017 Full text Link to item Cite

Outcomes of 27-Gauge Vitrectomy-Assisted Choroidal and Subretinal Biopsy.

Journal Article Ophthalmic Surg Lasers Imaging Retina · May 1, 2017 BACKGROUND AND OBJECTIVE: To report the initial experience of 27-gauge vitrectomy-assisted choroidal and subretinal biopsy PATIENTS AND METHODS: Retrospective, interventional case series. Eighteen eyes of 18 patients undergoing 27-gauge vitrectomy-assisted ... Full text Link to item Cite

Mixed hemangioblastoma and ependymoma collision tumor of the cerebellum.

Journal Article Clin Neuropathol · 2017 Full text Link to item Cite

Olfactory ensheathing cell tumor: a case presentation.

Journal Article Clin Neuropathol · 2017 Full text Link to item Cite

Long-Term Outcomes for Patients With Atypical or Malignant Meningiomas Treated With Radiation Therapy: A Single-Institution Retrospective Analysis.

Journal Article Int J Radiat Oncol Biol Phys · October 1, 2016 Full text Link to item Cite

"Diagnostic Algorithm for Patients With Suspected Giant Cell Arteritis" Useful, but No Substitute for Thorough Histopathology: Response.

Other J Neuroophthalmol · September 2016 Full text Link to item Cite

Diagnostic Algorithm for Suspected Giant Cell Arteritis: Response.

Other J Neuroophthalmol · June 2016 Full text Link to item Cite

Neuropathology of gliomas

Chapter · March 31, 2016 Full text Cite

Rhabdomyomatous mesenchymal hamartoma presenting as a sacral skin tag in two neonates with spinal dysraphism.

Journal Article J Cutan Pathol · October 2015 Rhabdomyomatous mesenchymal hamartoma (RMH) is a rare congenital malformation involving the dermis and subcutaneous tissue, of which there were 62 reported cases through 2014. We report RMH in two neonates presenting as a sacral skin tag. In both cases, ma ... Full text Link to item Cite

Diagnostic Algorithm for Patients With Suspected Giant Cell Arteritis.

Journal Article J Neuroophthalmol · September 2015 BACKGROUND: To identify clinical and laboratory factors contributing to the diagnosis of giant cell arteritis (GCA) and develop a diagnostic algorithm for the evaluation of GCA. METHODS: Retrospective review of 213 consecutive cases of temporal artery biop ... Full text Link to item Cite

An Extraordinary Association of Glomus Tumor and Pacinian Hyperplasia in the Hand of a Female Patient.

Journal Article Am J Dermatopathol · September 2015 BACKGROUND: Glomus tumor is a benign neoplasm of the glomus body, a neuromyoarterial structure that regulates temperature and pressure in the cutaneous vasculature. Approximately 1%-4.5% of glomus tumors present in the hands of females; of these, 65% are s ... Full text Link to item Cite

Eye and ocular adnexa

Chapter · January 21, 2015 Cite

Conjunctival pseudotumor caused by herpes simplex virus infection.

Journal Article JAMA Ophthalmol · January 2015 Full text Link to item Cite

Choroid plexus in the eye: a case study.

Journal Article Retin Cases Brief Rep · 2015 PURPOSE: The purpose of this report is to describe a pediatric case of total retinal detachment (RD) with secondary glaucoma in the setting of posterior coloboma with the metaplastic retinal pigment epithelium showing abrupt transition to choroid plexus ti ... Full text Link to item Cite

Conjunctival melanoma.

Other JAMA Ophthalmol · December 2014 Full text Link to item Cite

Ophthalmologic Pathology: SY20-1 OCULAR PATHOLOGY, AN OVERVIEW: RETINA AND OPTIC NERVE.

Journal Article Pathology · October 2014 The goal of this symposium is to present an overview of ocular pathology, and this lecture is dedicated to an overview of the pathology of the retina and optic nerve. The retina is a complex tissue lining the inner surface of the eye. It receives images fr ... Full text Link to item Cite

Unilateral microsporidia keratitis in a healthy non-contact lens wearer.

Journal Article JAMA Ophthalmol · July 2014 Full text Link to item Cite

Optimizing Laser Parameters for Pump-Probe Microscopy of Conjunctival Melanocytic Lesions

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

TTF-1 Is Expressed in a Subset of Esophageal Adenocarcinomas

Conference MODERN PATHOLOGY · February 1, 2014 Link to item Cite

TTF-1 Is Expressed in a Subset of Esophageal Adenocarcinomas

Conference LABORATORY INVESTIGATION · February 1, 2014 Link to item Cite

Choroidal metastatasis from a neuroendocrine tumor masquerading as choroidal melanoma.

Journal Article Ophthalmic Surg Lasers Imaging Retina · 2014 A mushroom-shaped choroidal mass is classically suggestive of melanoma, due to the ability of these tumors to erupt through Bruch's membrane. In contrast, choroidal metastases rarely adopt this growth pattern. The authors present an unusual case of a patie ... Full text Link to item Cite

Imaging microscopic pigment chemistry in conjunctival melanocytic lesions using pump-probe laser microscopy.

Journal Article Invest Ophthalmol Vis Sci · October 21, 2013 PURPOSE: To report the application of a novel imaging technique, pump-probe microscopy, to analyze patterns of pigment chemistry of conjunctival melanocytic lesion biopsies. METHODS: Histopathologic specimens of eight previously excised conjunctival melano ... Full text Link to item Cite

Symptomatic Rathke's cleft cyst with a co-existing pituitary tumor; Brief review of the literature.

Journal Article Asian J Neurosurg · October 2013 Pituitary adenomas and Rathke's cleft cysts (RCCs) share a common embryological origin. Occasionally, these two lesions can present within the same patient. We present a case of a 39-year-old male who was found to have a large sellar lesion after complaint ... Full text Link to item Cite

Treatment and outcomes of epithelioid sarcoma of the spine.

Journal Article J Clin Neurosci · October 2013 Epithelioid sarcoma (ES) is a rare soft-tissue neoplasm which is most commonly found in the extremities of young adult males. ES has a poor prognosis due to its aggressiveness as it frequently recurs locally and can undergo lymphatic metastasis to soft tis ... Full text Link to item Cite

Uncorrectable ptosis: primary cutaneous signet-ring cell carcinoma.

Journal Article Dermatol Online J · September 14, 2013 Primary cutaneous signet-ring cell carcinoma (PCSRCC) is a rare but aggressive tumor. Our case highlights a 60-year-old man who presented with eyelid ptosis, for which he underwent multiple surgical procedures over a 3-year period prior to referral to our ... Link to item Cite

Uncorrectable ptosis: primary cutaneous signet-ring cell carcinoma.

Journal Article Dermatology online journal · September 1, 2013 Primary cutaneous signet-ring cell carcinoma (PCSRCC) is a rare but aggressive tumor. Our case highlights a 60-year-old man who presented with eyelid ptosis, for which he underwent multiple surgical procedures over a 3-year period prior to referral to our ... Cite

Adult primitive neuroectodermal tumors: the prognostic value of supratentorial location.

Journal Article J Neurooncol · August 2013 Primitive neuroectodermal tumors (PNETs) are tumors which primarily consist of undifferentiated round neuroepithelial cells. Central nervous system PNETs can be divided into two genetically distinct groups: infratentorial PNET (iPNET)/medulloblastoma and s ... Full text Link to item Cite

Clinicopathological characteristics and treatment of rhabdoid glioblastoma.

Journal Article J Neurosurg · August 2013 OBJECT: Rhabdoid glioblastoma (GB) is an exceedingly rare tumor in which some of the tumor cells possess rhabdoid features such as eccentric nuclei, abundant eosinophilic cytoplasm, and pseudopapillary formations. These tumors are exceptionally aggressive, ... Full text Link to item Cite

Imaging pigment chemistry in melanocytic conjunctival lesions with pump-probe microscopy

Chapter · June 7, 2013 We extend nonlinear pump-probe microscopy, recently demonstrated to image the microscopic distribution of eumelanin and pheomelanin in unstained skin biopsy sections, to the case of melanocytic conjunctival lesions. The microscopic distribution of pigmenta ... Full text Cite

Spinal cavernous and capillary hemangiomas in adults.

Journal Article Spine (Phila Pa 1976) · April 1, 2013 STUDY DESIGN: Retrospective cohort analysis. OBJECTIVE: To evaluate the neurological outcomes after resection of intramedullary, intradural extramedullary, and extradural hemangiomas. SUMMARY OF BACKGROUND DATA: Spinal hemangiomas most commonly arise in th ... Full text Link to item Cite

Glioblastoma of the Optic Nerve

Conference MODERN PATHOLOGY · February 1, 2013 Link to item Cite

Glioblastoma of the Optic Nerve

Conference LABORATORY INVESTIGATION · 2013 Cite

Ophthalmic Pathology A Concise Guide

Book · October 2, 2012 The volume differs from the available classic and comprehensive ophthalmic pathology textbooks in its basic and simplified ‘one month approach’ concept. ... Cite

Normal Eye and Ocular Adnexa

Chapter · July 16, 2012 Cite

Congenital ectropion uvea and mechanisms of glaucoma in neurofibromatosis type 1: new insights.

Journal Article Ophthalmology · July 2012 OBJECTIVE: To describe the clinicopathologic features of congenital ectropion uvea associated with glaucoma in neurofibromatosis-1 (NF-1). DESIGN: Retrospective case series. PARTICIPANTS AND CONTROLS: Five cases of NF-1 associated with glaucoma, from which ... Full text Link to item Cite

Disseminated Intracranial Ewing's Sarcoma in an Adult: A Rare and Difficult Diagnosis.

Journal Article Case Rep Oncol · May 2012 The Ewing sarcoma family of tumors comprises a rare class of cancers of mesenchymal origin. Cases of Ewing's sarcoma in the central nervous system - specifically, intracranial Ewing's - are extremely rare. Almost all reported cases have occurred in childre ... Full text Link to item Cite

Catecholamine-secreting paraganglioma of the thoracic spinal column: report of an unusual case and review of the literature.

Journal Article Neurosurgery · April 2012 BACKGROUND AND IMPORTANCE: Paragangliomas are rare tumors of neuroendocrine origin that arise from paraganglionic tissue of the extrachromaffin cell system. These lesions may be seen at various sites along the neuraxis. Primary thoracic paragangliomas have ... Full text Link to item Cite

Rapidly regulating platelet activity in vivo with an antidote controlled platelet inhibitor.

Journal Article Mol Ther · February 2012 Millions of individuals are prescribed platelet inhibitors, such as aspirin and clopidogrel, to reduce their risk of thrombosis-related clinical events. Unfortunately many platelet inhibitors are contraindicated in surgical settings because of their inhere ... Full text Link to item Cite

Primary Signet-Ring/Histiocytoid Carcinoma of the Eyelid

Conference LABORATORY INVESTIGATION · February 1, 2012 Link to item Cite

Primary Signet-Ring/Histiocytoid Carcinoma of the Eyelid

Conference MODERN PATHOLOGY · 2012 Cite

Inflammatory pseudotumor of the lateral ventricle in a pediatric patient.

Journal Article Pediatr Neurosurg · 2012 Inflammatory pseudotumor (IP) is a benign process that most commonly occurs in the lung and orbit. Extension into the central nervous system is extremely rare, and primary intraventricular lesions of the lateral ventricles are even more infrequent with onl ... Full text Link to item Cite

Sudden death from diffuse leptomeningeal oligodendrogliomatosis.

Journal Article J Neurosurg Spine · December 2011 In this paper the authors describe the rare disorder of diffuse leptomeningeal oligodendrogliomatosis in a patient with an oligodendroglioma of the cauda equina who died suddenly. Reviewing this uncommon pathological entity is important so that it can be r ... Full text Link to item Cite

Giant sacral metastasis of Hurthle cell thyroid carcinoma: Case report and review of the literature

Journal Article Journal of Surgical Radiology · December 1, 2011 Overview Management of spinal sacral masses requires a discrete algorithm for both diagnosis and treatment. Here we use a case report to illustrate the importance of biopsy in the management of a sacral mass. In this case, a woman who had been offered an e ... Cite

Survival risk assessment for primary blast exposures to the head.

Journal Article J Neurotrauma · November 2011 Many soldiers returning from the current conflicts in Iraq and Afghanistan have had at least one exposure to an explosive event and a significant number have symptoms consistent with traumatic brain injury. Although blast injury risk functions have been de ... Full text Link to item Cite

Primary intradural extraosseous Ewing sarcoma of the spine: case report and literature review.

Journal Article Neurosurgery · October 2011 BACKGROUND AND IMPORTANCE: To report a rare case of spinal intradural extraosseous Ewing sarcoma in an adult and review current literature. Although Ewing sarcoma belongs to the family, the treatment modalities are different, and thus the correct diagnosis ... Full text Link to item Cite

Calcifying pseudoneoplasm of the cerebellopontine angle: case report.

Journal Article Neurosurgery · September 2011 BACKGROUND AND IMPORTANCE: Calcifying pseudoneoplasms are rare tumors of the neuraxis. To our knowledge, this is only the second reported case in the literature of calcifying pseudoneoplasm of the cerebellopontine angle. The etiology and natural history of ... Full text Link to item Cite

Hematolymphoid malignancies with intraocular intravascular involvement: report of 2 cases.

Journal Article Ann Diagn Pathol · August 2011 The interaction between the endothelium and malignant hematolymphoid cells within vessels of the eye can result in focal or diffuse intravascular pathology. As a result, correlation of these findings with specific clinical and ophthalmologic features can v ... Full text Link to item Cite

Complications following decompression of Chiari malformation Type I in children: dural graft or sealant?

Journal Article J Neurosurg Pediatr · August 2011 OBJECT: Posterior fossa decompression with duraplasty for Chiari malformation Type I (CM-I) is a common pediatric neurosurgery procedure. Published series report a complication rate ranging from 3% to 40% for this procedure. Historically, many dural substi ... Full text Link to item Cite

Transformation of juvenile pilocytic astrocytoma to anaplastic pilocytic astrocytoma in patients with neurofibromatosis type I.

Journal Article J Pediatr Hematol Oncol · July 2011 Patients with juvenile pilocytic astrocytoma (JPA) and neurofibromatosis type I (NF-1) tend to have a more indolent course than those with sporadic tumors. In rare circumstances, transformation to anaplastic pilocytic astrocytoma (APA) has been known to oc ... Full text Link to item Cite

Chronic Progressive External Ophthalmoplegia: A Report of 2 Cases.

Conference LABORATORY INVESTIGATION · February 1, 2011 Link to item Cite

Chronic Progressive External Ophthalmoplegia: A Report of 2 Cases

Conference MODERN PATHOLOGY · February 1, 2011 Link to item Cite

Fourth ventricular schwannoma: identical clinicopathologic features as schwann cell-derived schwannoma with unique etiopathologic origins.

Journal Article Case Rep Med · 2011 Background. To our knowledge, this is the sixth reported case in the literature of fourth ventricular schwannoma. The etiology and natural history of intraventricular schwannomas is not well understood. A thorough review of potential etiopathogenic mechani ... Full text Link to item Cite

Primary meningeal rhabdomyosarcoma.

Journal Article Sarcoma · 2011 Primary meningeal rhabdomyosarcoma is a rare primary brain malignancy, with scant case reports. While most reports of primary intracranial rhabdomyosarcoma occur in pediatric patients, a handful of cases in adult patients have been reported in the medical ... Full text Link to item Cite

Nodular fasciitis presenting in an adult woman.

Journal Article Ophthalmic Plast Reconstr Surg · 2011 The authors report a 30-year-old Caucasian woman with nodular fasciitis presenting as a nontender lesion to right temporal area. The lesion was removed by en bloc excision and the base was cauterized. Six months later, the patient returned to the clinic fo ... Full text Link to item Cite

Primary intracerebral Hodgkin lymphoma with recurrence.

Journal Article Clin Neuropathol · 2011 OBJECTIVE: To report a case of primary intracerebral Hodgkin lymphoma with disease recurrence. METHODS: Case report and review of the literature. RESULTS: A 58-year-old immunocompetent male presented with aphasia. Neuroimaging revealed a left temporal lobe ... Full text Link to item Cite

Long-term safety of combined intracerebral delivery of free gadolinium and targeted chemotherapeutic agent PRX321.

Journal Article Neurol Res · October 2010 OBJECTIVES: While convection enhanced delivery (CED) is an effective delivery method that bypasses the blood-brain barrier, its utility is limited by infusate leakage due to catheter misplacement. Therefore, it is critical to evaluate drug distribution dur ... Full text Link to item Cite

Angiosarcoma of the eyelid: a clinicopathologic comparison between isolated unilateral tumors and tumors demonstrating extrapalpebral involvement.

Journal Article Am J Dermatopathol · October 2010 Angiosarcomas involving the head and neck are malignant tumors which tend to involve multiple anatomical structures with an overall dismal prognosis. Reports of primary, isolated eyelid involvement are rare. We report 4 cases of angiosarcoma involving the ... Full text Link to item Cite

Endodermal cyst of the oculomotor nerve.

Journal Article Pediatr Neurosurg · August 2010 Full text Link to item Cite

Neurothekeoma palpebrae: A report of 3 cases.

Journal Article Am J Dermatopathol · June 2010 Featured Publication Neurothekeoma palpebrae is the diagnostic term used to describe nerve sheath myxoma or neurothekeoma of the eyelid. Although these tumors are not uncommonly found in the head and neck region, eyelid involvement is very uncommon. We present 2 cases of cellu ... Full text Link to item Cite

Response of malignant scalp dermatofibrosarcoma to presurgical targeted growth factor inhibition.

Journal Article J Neurosurg · May 2010 Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive, malignant cutaneous tumor that sparingly presents on the scalp. Dermatofibrosarcomas often result from the formation of a fusion oncogene on translocated or supernumerary ring chrom ... Full text Link to item Cite

Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1.

Journal Article J Neurooncol · May 2010 A major obstacle in glioblastoma (GBM) therapy is the restrictive nature of the blood-brain barrier (BBB). Convection-enhanced delivery (CED) is a novel method of drug administration which allows direct parenchymal infusion of therapeutics, bypassing the B ... Full text Link to item Cite

Erratum: Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1 (Journal of Neuro-Oncology DOI 10.1007/s11060-009-0046-7)

Journal Article Journal of Neuro-Oncology · May 1, 2010 Full text Cite

The eye and ocular adnexa

Chapter · February 3, 2010 Cite

Symptomatic Traumatic Neuroma Causing Common Bile Duct Stricture Following Orthotopic Liver Transplantation: A Retrospective Three and a Half Year Review

Conference LABORATORY INVESTIGATION · February 1, 2010 Link to item Cite

Symptomatic Traumatic Neuroma Causing Common Bile Duct Stricture Following Orthotopic Liver Transplantation: A Retrospective Three and a Half Year Review

Conference MODERN PATHOLOGY · February 1, 2010 Link to item Cite

Angiosarcoma of the Eyelid: A Clinicopathologic Comparison between Isolated Unilateral Eyelid Tumors and Tumors Demonstrating Extra-Palpebral Involvement

Conference MODERN PATHOLOGY · February 1, 2010 Link to item Cite

Angiosarcoma of the Eyelid: A Clinicopathologic Comparison between Isolated Unilateral Eyelid Tumors and Tumors Demonstrating Extra-Palpebral Involvement

Conference LABORATORY INVESTIGATION · February 1, 2010 Link to item Cite

Ultrasonographic appearance of intraneural injections in the porcine model.

Journal Article Reg Anesth Pain Med · 2010 BACKGROUND: Ultrasonographic (US) images of apparent intraneural injection of local anesthetic solutions have been reported. We aimed to define US signs of intraneural (ie, subepineural) injection using a histologic standard in an animal model and compare ... Full text Link to item Cite

Disappearing bone disease and Chiari I malformation.

Journal Article Pediatr Neurosurg · 2010 Gorham's disease is a rare disorder in which massive osteolysis occurs within bone, and therefore earns its historical name: disappearing bone disease. We describe a case of Chiari I malformation in a patient with this rare disorder, with treatment consist ... Full text Link to item Cite

Corneal wound architecture and integrity after torsional and mixed phacoemulsification: evaluation of standard and microincisional coaxial techniques.

Journal Article Ophthalmic Surg Lasers Imaging · 2010 BACKGROUND AND OBJECTIVE: To compare the effects of torsional and mixed ultrasound on clear corneal incision architecture, wound integrity, and apposition using standard (2.75 mm) and microincisional (2.2 mm) coaxial phacoemulsification. SUBJECTS AND METHO ... Full text Link to item Cite

Isolated intracranial Rosai-Dorfman disease in a child.

Journal Article AJNR Am J Neuroradiol · November 2009 Full text Link to item Cite

Clinical and ocular pathological findings in Von Hippel-Lindau disease

Journal Article Clinical and Surgical Ophthalmology · June 1, 2009 Objectives: To report a patient with Von Hippel-Lindau (VHL) disease demonstrating classic ocular findings. Design'. Retrospective case report. Methods: Clinical and pathological findings. Main Outcome Measures: Clinical course and pathological findings. R ... Cite

Primary intramedullary melanocytoma of the spinal cord: case report.

Journal Article Neurosurgery · April 2009 OBJECTIVE: The authors report 2 cases of primary intramedullary spinal melanocytomas in 2 patients who presented with lower extremity numbness and/or weakness. CLINICAL PRESENTATION: Magnetic resonance imaging of the spine, thoracic laminectomy, and histol ... Full text Link to item Cite

Adult cases of leukoencephalopathy, cerebral calcifications, and cysts: expanding the spectrum of the disorder.

Journal Article J Neuropathol Exp Neurol · April 2009 Leukoencephalopathy with cerebral calcifications and cysts (LCC) was first reported in children who developed cognitive decline and variable extrapyramidal, cerebellar, and pyramidal signs, with or without seizures. Leukoencephalopathy with cerebral calcif ... Full text Link to item Cite

Ectopic brain in the orbit presenting as disc edema in an adult.

Journal Article Orbit · 2009 A 59-year-old man presented with disc edema in the right eye. MRI demonstrated a lesion extending to the orbital apex. The lesion was biopsied and pathology revealed ectopic brain tissue. The presence of ectopic brain in the orbit is a rare finding. The fe ... Full text Link to item Cite

Secretory meningiomas of the orbit.

Journal Article Orbit · 2009 Featured Publication Meningiomas are histologically heterogeneous tumors with at least 15 different subtypes. They can be subdivided into well-differentiated, atypical, and anaplastic or malignant categories. The secretory meningioma is a well-differentiated variant, is relati ... Full text Link to item Cite

Hereditary benign intraepithelial dyskeratosis: an evaluation of diagnostic cytology.

Journal Article Arch Pathol Lab Med · August 2008 Featured Publication CONTEXT: Hereditary benign intraepithelial dyskeratosis (HBID) is a rare autosomal dominant disorder characterized by elevated epibulbar and oral plaques and hyperemic conjunctival blood vessels. The condition is predominantly seen in Native Americans belo ... Full text Link to item Cite

The presence of T-lymphocyte subpopulations (CD4 and CD8) in pterygia: evaluation of the inflammatory response.

Journal Article Adv Ther · May 2008 INTRODUCTION: The aim of our study was to confirm the presence of inflammatory T-lymphocyte subpopulations (CD4 and CD8) in pterygium specimens with regards to clinical severity. Additionally, we examined the effect of topical anti-inflammatory agents on t ... Full text Link to item Cite

Cholesterol granuloma of the lateral ventricle. Case report.

Journal Article J Neurosurg · February 2008 Cholesterol granulomas (CGs) are benign lesions resulting from an inflammatory reaction to cholesterol and hemosiderin. These masses most often arise within the temporal bone or nasal sinuses; intracerebral CGs are extremely rare. In this report the author ... Full text Link to item Cite

Unusual case of diffuse choroidal melanoma masquerading as atypical central serous chorioretinopathy.

Journal Article Retin Cases Brief Rep · 2008 PURPOSE: To describe an unusual case of diffuse circumpapillary choroidal melanoma masquerading as atypical central serous chorioretinopathy, and to describe fluorescein angiographic and optical coherence tomography characteristics of this diffuse choroida ... Full text Link to item Cite

Hybrid neurofibroma-schwannoma of the orbit.

Journal Article Orbit · 2008 PURPOSE: To report a case of an unusual orbital tumor with histologic features of both neurofibroma and schwannoma. METHODS: Clinical and pathological findings are presented in a patient with an orbital tumor. RESULTS: Orbital magnetic resonance imaging in ... Full text Link to item Cite

Stage IV primitive-appearing sinus and orbital rhabdomyosarcoma presenting in a 68-year-old female previously treated for breast cancer.

Journal Article Orbit · 2008 A 68-year-old female who had undergone treatment several years previously for breast cancer presented with diplopia and unilateral proptosis and exposure keratopathy related to biopsy-proven rhabdomyosarcoma of the sinus and orbit. Further evaluation revea ... Full text Link to item Cite

Choroidal metastasis of follicular thyroid adenocarcinoma diagnosed by 25-gauge transretinal biopsy.

Journal Article Ann Ophthalmol (Skokie) · 2008 We report a case of a patient with previously treated follicular thyroid carcinoma who presented with a symptomatic amelanotic choroidal mass with low internal reflectivity and a metastatic lytic skull lesion. A 25-gauge vitrector was used to perform trans ... Link to item Cite

Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function.

Journal Article Clin Cancer Res · April 1, 2007 PURPOSE: Patients with malignant glioma suffer global compromise of their cellular immunity, characterized by dramatic reductions in CD4(+) T cell numbers and function. We have previously shown that increased regulatory T cell (T(reg)) fractions in these p ... Full text Link to item Cite

Cerebellar cryptococcoma in a patient with undiagnosed sarcoidosis: case report.

Journal Article Neurosurgery · March 2007 OBJECTIVE: We describe a patient with undiagnosed sarcoidosis who presented with a rare isolated cerebellar cryptococcoma masquerading as a metastatic brain tumor. CLINICAL PRESENTATION: A 58-year-old man with a history of resected squamous cell carcinoma ... Full text Link to item Cite

Intraocular epithelial tumors and cysts

Chapter · January 1, 2007 Neuroepithelial tumors of the eye are rare and typically occur in the ciliary body but can also involve the iris and retina. They may be congenital or acquired. Congenital tumors include medulloepitheliomas and glioneuromas, while acquired tumors include a ... Cite

Ocular involvement in disorders of the nervous system

Chapter · January 1, 2007 Vision, one of the most complex of all sensations interpreted by the nervous system, is dependent upon the integrity of pathways within the brain that comprise neurons, neuroglia, as well as blood vessels and other connective tissue elements. ... Cite

Tumors of the optic nerve, peripheral nerves, and autonomic nervous system

Chapter · January 1, 2007 This chapter reviews neoplasms of the central, peripheral, and autonomic nervous systems as they relate to the eye, optic nerve, and orbit. Ocular tissues are potential sites of origin for tumors derived from the peripheral and autonomic nervous systems. T ... Cite

Primary cerebral ALK-1-positive anaplastic large cell lymphoma in a child. Case report and literature review.

Journal Article Pediatr Neurosurg · 2007 A 4-year-old African American male was referred to the Pediatric Neurosurgery Service for evaluation of new onset seizures and worsening mental status. An MRI of the brain revealed a pineal region mass with diffuse leptomeningeal enhancement and compressio ... Full text Link to item Cite

Spinal capillary hemangioma in infants: report of two cases and review of the literature.

Journal Article Pediatr Neurosurg · 2007 We report the case of 2 infants born with a lumbar dermal sinus tract and an overlying angiomatous skin lesion referred to our pediatric neurosurgery service for evaluation of a tethered cord. Both infants were born with a lumbar dimple and were found to h ... Full text Link to item Cite

Primary spinal intramedullary adrenal cortical adenoma associated with spinal dysraphism: case report.

Journal Article Neurosurgery · November 2006 Featured Publication OBJECTIVE: The authors report a primary spinal intramedullary adrenal cortical adenoma in a patient with spinal dysraphism presenting with bilateral leg pain and urinary frequency. METHODS: Magnetic resonance imaging, L2 laminectomy with resection of mass, ... Full text Link to item Cite

Behavioural testing and histological assessments of rabbit spinal cord following intrathecal administration of ondansetron.

Journal Article Clin Exp Pharmacol Physiol · September 2006 1. Intrathecal injection of ondansetron has the potential to reduce opioid-related side-effects. The aim of the present study was to determine whether this route of administration produces neuraxial injury. 2. Adult, non-pregnant female New Zealand white r ... Full text Link to item Cite

Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells.

Journal Article Clin Cancer Res · July 15, 2006 PURPOSE: Elevated proportions of regulatory T cells (T(reg)) are present in patients with a variety of cancers, including malignant glioma, yet recapitulative murine models are wanting. We therefore examined T(regs) in mice bearing malignant glioma and eva ... Full text Link to item Cite

Complex choristoma of the gyrus rectus: a distinct clinicopathologic entity?

Journal Article Am J Surg Pathol · May 2006 Featured Publication We report 2 cases of an unusual central nervous system lesion involving the gyrus rectus and characterized by well-differentiated epithelial and mesenchymal components. One patient was a 30-year-old woman, and the other was a 42-year-old man. Both presente ... Full text Link to item Cite

Primary myxoma of the parafalcine meninges. Case report.

Journal Article J Neurosurg · March 2006 The authors report on an unusual case of a primary intracranial myxoma in a 39-year-old woman. The patient presented with headache and generalized seizure. Magnetic resonance imaging revealed a large right frontal tumor resembling a parasagittal meningioma ... Full text Link to item Cite

Capillary hemangioma of the fourth ventricle in an infant. Case report and review of the literature.

Journal Article J Neurosurg · March 2006 A 3-month-old boy presented to the pediatric neurosurgery service with central hypotonia. Magnetic resonance images of the brain revealed a homogeneously enhancing dumbbell-shaped mass located in the fourth ventricle and extending into the left cerebellopo ... Full text Link to item Cite

Capillary hemangioma of the fourth ventricle in an infant. Case report and review of the literature.

Journal Article Journal of neurosurgery. · March 1, 2006 A 3-month-old boy presented to the pediatric neurosurgery service with central hypotonia. Magnetic resonance images of the brain revealed a homogeneously enhancing dumbbell-shaped mass located in the fourth ventricle and extending into the left cerebellopo ... Cite