A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy.
Publication
, Journal Article
Eichenberger, EM; Saullo, J; Brander, D; Wang, S-H; Perfect, JR; Messina, JA
Published in: Medical mycology case reports
March 2020
Ibrutinib has revolutionized the treatment of chronic lymphoid malignancies. Despite its success, ibrutinib has been linked with several reports of invasive fungal infections. We present a case of CNS aspergillosis in a CLL patient on first line ibrutinib therapy. We summarize existing case reports and case series of invasive aspergillosis in patients on ibrutinib, the pathogenesis of invasive aspergillosis, and discuss the clinical controversies regarding anti-fungal prophylaxis in this population.
Duke Scholars
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Published In
Medical mycology case reports
DOI
EISSN
2211-7539
ISSN
2211-7539
Publication Date
March 2020
Volume
27
Start / End Page
17 / 21
Related Subject Headings
- 3207 Medical microbiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Eichenberger, E. M., Saullo, J., Brander, D., Wang, S.-H., Perfect, J. R., & Messina, J. A. (2020). A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy. Medical Mycology Case Reports, 27, 17–21. https://doi.org/10.1016/j.mmcr.2019.12.007
Eichenberger, Emily M., Jennifer Saullo, Danielle Brander, Shih-Hsiu Wang, John R. Perfect, and Julia A. Messina. “A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy.” Medical Mycology Case Reports 27 (March 2020): 17–21. https://doi.org/10.1016/j.mmcr.2019.12.007.
Eichenberger EM, Saullo J, Brander D, Wang S-H, Perfect JR, Messina JA. A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy. Medical mycology case reports. 2020 Mar;27:17–21.
Eichenberger, Emily M., et al. “A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy.” Medical Mycology Case Reports, vol. 27, Mar. 2020, pp. 17–21. Epmc, doi:10.1016/j.mmcr.2019.12.007.
Eichenberger EM, Saullo J, Brander D, Wang S-H, Perfect JR, Messina JA. A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy. Medical mycology case reports. 2020 Mar;27:17–21.
Published In
Medical mycology case reports
DOI
EISSN
2211-7539
ISSN
2211-7539
Publication Date
March 2020
Volume
27
Start / End Page
17 / 21
Related Subject Headings
- 3207 Medical microbiology