Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry.

Publication ,  Journal Article
Plassman, BL; Steffens, DC; Burke, JR; Welsh-Bohmer, KA; Newman, TN; Drosdick, D; Helms, MJ; Potter, GG; Breitner, JCS
Published in: Twin Res Hum Genet
December 2006

The Duke Twins Study of Memory in Aging is an ongoing, longitudinal study of cognitive change and dementia in the population-based National Academy of Sciences-National Research Council (NAS-NRC) Twin Registry of World War II Male Veterans. The primary goal of this study has been to estimate the overall genetic and environmental contributions to dementia with a specific focus on Alzheimer's disease. An additional goal has been to examine specific genetic and environmental antecedents of cognitive decline and dementia. Since 1989, we have completed 4 waves of data collection. Each wave included a 2-phase telephone cognitive screening protocol, followed by an in-home standardized clinical assessment for those with suspected dementia. For many participants, we have obtained postmortem neuropathological confirmation of the diagnosis of dementia. In addition to data on cognition, we have also collected information on occupational history, medical history, medications and other lifetime experiences that may influence cognitive function in late life. We provide an overview of the study's methodology and describe the focus of recent research.

Duke Scholars

Published In

Twin Res Hum Genet

DOI

ISSN

1832-4274

Publication Date

December 2006

Volume

9

Issue

6

Start / End Page

950 / 957

Location

England

Related Subject Headings

  • Veterans
  • United States
  • Twins, Monozygotic
  • Twins, Dizygotic
  • Registries
  • North Carolina
  • Memory
  • Male
  • Humans
  • Genetics & Heredity
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Plassman, B. L., Steffens, D. C., Burke, J. R., Welsh-Bohmer, K. A., Newman, T. N., Drosdick, D., … Breitner, J. C. S. (2006). Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry. Twin Res Hum Genet, 9(6), 950–957. https://doi.org/10.1375/183242706779462381
Plassman, Brenda L., David C. Steffens, James R. Burke, Kathleen A. Welsh-Bohmer, Tiffany N. Newman, Deborah Drosdick, Michael J. Helms, Guy G. Potter, and John C. S. Breitner. “Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry.Twin Res Hum Genet 9, no. 6 (December 2006): 950–57. https://doi.org/10.1375/183242706779462381.
Plassman BL, Steffens DC, Burke JR, Welsh-Bohmer KA, Newman TN, Drosdick D, et al. Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry. Twin Res Hum Genet. 2006 Dec;9(6):950–7.
Plassman, Brenda L., et al. “Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry.Twin Res Hum Genet, vol. 9, no. 6, Dec. 2006, pp. 950–57. Pubmed, doi:10.1375/183242706779462381.
Plassman BL, Steffens DC, Burke JR, Welsh-Bohmer KA, Newman TN, Drosdick D, Helms MJ, Potter GG, Breitner JCS. Duke Twins Study of Memory in Aging in the NAS-NRC Twin Registry. Twin Res Hum Genet. 2006 Dec;9(6):950–957.
Journal cover image

Published In

Twin Res Hum Genet

DOI

ISSN

1832-4274

Publication Date

December 2006

Volume

9

Issue

6

Start / End Page

950 / 957

Location

England

Related Subject Headings

  • Veterans
  • United States
  • Twins, Monozygotic
  • Twins, Dizygotic
  • Registries
  • North Carolina
  • Memory
  • Male
  • Humans
  • Genetics & Heredity