Scholars@Duke
Douglas Charles McCrory

Douglas Charles McCrory

Adjunct Associate Professor in the Department of Medicine
Medicine, General Internal Medicine
douglas.mccrory@duke.edu
Box 3850 Med Ctr, Durham, NC 27710
PO Box 17969, Room 0311/Terrace Level, Durham, NC 27715

Selected Publications

Flunarizine as prophylaxis for episodic migraine: a systematic review with meta-analysis.

Journal Article Pain · April 2019 Based on few clinical trials, flunarizine is considered a first-line prophylactic treatment for migraine in several guidelines. In this meta-analysis, we examined the pooled evidence for its effectiveness, tolerability, and safety. Prospective randomized c ... Full text Link to item Cite

Biofeedback as Prophylaxis for Pediatric Migraine: A Meta-analysis.

Journal Article Pediatrics · August 2016 CONTEXT: Migraine is a common problem in children and adolescents, but few satisfactory prophylactic treatments exist. OBJECTIVE: Our goal was to investigate the pooled evidence for the effectiveness of using biofeedback to reduce childhood migraine. DATA ... Full text Link to item Cite

Interpretive Diagnostic Error Reduction in Surgical Pathology and Cytology: Guideline From the College of American Pathologists Pathology and Laboratory Quality Center and the Association of Directors of Anatomic and Surgical Pathology.

Journal Article Arch Pathol Lab Med · January 2016 CONTEXT: Additional reviews of diagnostic surgical and cytology cases have been shown to detect diagnostic discrepancies. OBJECTIVE: To develop, through a systematic review of the literature, recommendations for the review of pathology cases to detect or p ... Full text Link to item Cite

Benefits and Harms of Breast Cancer Screening: A Systematic Review.

Journal Article JAMA · October 20, 2015 IMPORTANCE: Patients need to consider both benefits and harms of breast cancer screening. OBJECTIVE: To systematically synthesize available evidence on the association of mammographic screening and clinical breast examination (CBE) at different ages and in ... Full text Link to item Cite

Oxygen for relief of dyspnoea in people with chronic obstructive pulmonary disease who would not qualify for home oxygen: a systematic review and meta-analysis.

Journal Article Thorax · May 2015 We searched MEDLINE, EMBASE and the Cochrane Controlled Trials Register to determine whether oxygen relieves dyspnoea in mildly or non-hypoxemic COPD and included 18 randomised controlled trials (431 participants) in the meta-analysis using Cochrane method ... Full text Link to item Cite

Tools for assessing outcomes in studies of chronic cough: CHEST guideline and expert panel report.

Journal Article Chest · March 2015 BACKGROUND: Since the publication of the 2006 American College of Chest Physicians (CHEST) cough guidelines, a variety of tools has been developed or further refined for assessing cough. The purpose of the present committee was to evaluate instruments used ... Full text Link to item Cite

Antiepileptics in migraine prophylaxis: an updated Cochrane review.

Journal Article Cephalalgia · January 2015 INTRODUCTION: The efficacy of several antiepileptics in the preventive treatment of episodic migraine in adults has been systematically reviewed. Because many trial reports have been published since then, an updated systematic review was warranted. METHODS ... Full text Link to item Cite

A proposed approach may help systematic reviews retain needed expertise while minimizing bias from nonfinancial conflicts of interest.

Journal Article J Clin Epidemiol · November 2014 OBJECTIVES: Groups such as the Institute of Medicine emphasize the importance of attention to financial conflicts of interest. Little guidance exists, however, on managing the risk of bias for systematic reviews from nonfinancial conflicts of interest. We ... Full text Link to item Cite

Overview of the management of cough: CHEST Guideline and Expert Panel Report.

Journal Article Chest · October 2014 This overview will demonstrate that cough is a common and potentially expensive health-care problem. Improvement in the quality of care of those with cough has been the focus of study for a variety of disciplines in medicine. The purpose of the Cough Guide ... Full text Link to item Cite

Prioritization of patient-centered comparative effectiveness research for osteoarthritis.

Journal Article Ann Intern Med · June 17, 2014 Osteoarthritis is a leading cause of disability in the United States. This article describes a prioritized research agenda about osteoarthritis management developed for the Patient-Centered Outcomes Research Institute. Evidence gaps were identified by revi ... Full text Link to item Cite

Comparative effectiveness and safety of drug therapy for pulmonary arterial hypertension: a systematic review and meta-analysis.

Journal Article Chest · May 2014 BACKGROUND: Current treatments for pulmonary arterial hypertension (PAH) have been shown to improve dyspnea, 6-min walk distance (6MWD), and pulmonary hemodynamics, but few studies were designed to compare treatment regimens or assess the impact of treatme ... Full text Link to item Cite

Prioritization of research addressing management strategies for ductal carcinoma in situ.

Journal Article Ann Intern Med · April 1, 2014 Ductal carcinoma in situ is a common finding in women having mammography screening, and there is considerable uncertainty about the balance of harms and benefits of different management options. This article outlines the process for developing a prioritize ... Full text Link to item Cite

Prioritization of research addressing antipsychotics for adolescents and young adults with bipolar disorder.

Journal Article Ann Intern Med · April 1, 2014 Despite a paucity of high-quality evidence about benefits and harms, antipsychotic medication use among adolescents and young adults with bipolar disorder is increasing. The Patient-Centered Outcomes Research Institute tasked the Duke Evidence Synthesis Gr ... Full text Link to item Cite

Efficacy and tolerability of treatments for chronic cough: a systematic review and meta-analysis.

Journal Article Chest · December 2013 BACKGROUND: Understanding the comparative effectiveness of treatments for patients with unexplained or refractory cough is important to increase awareness of proven therapies and their potential adverse effects in this unique population. METHODS: We perfor ... Full text Link to item Cite

Evaluating cough assessment tools: a systematic review.

Journal Article Chest · December 2013 BACKGROUND: Little is known about the comparative validity, reliability, or responsiveness of instruments for assessing cough frequency or impact, where the term impact encompasses both cough severity and the impact of cough on health-related quality of li ... Full text Link to item Cite

Antiepileptics other than gabapentin, pregabalin, topiramate, and valproate for the prophylaxis of episodic migraine in adults.

Journal Article Cochrane Database Syst Rev · June 24, 2013 BACKGROUND: Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an update of ... Full text Link to item Cite

Gabapentin or pregabalin for the prophylaxis of episodic migraine in adults.

Journal Article Cochrane Database Syst Rev · June 24, 2013 BACKGROUND: Some antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an update of ... Full text Link to item Cite

Topiramate for the prophylaxis of episodic migraine in adults.

Journal Article The Cochrane database of systematic reviews · June 2013 BackgroundSome antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an upd ... Full text Cite

Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults.

Journal Article The Cochrane database of systematic reviews · June 2013 BackgroundSome antiepileptic drugs but not others are useful in clinical practice for the prophylaxis of migraine. This might be explained by the variety of actions of these drugs in the central nervous system. The present review is part of an upd ... Full text Cite

Assessment and Management of Chronic Cough.

Journal Article AHRQ Comparative Effectiveness Reviews · January 2013 Cite

WITHDRAWN: Oral sumatriptan for acute migraine.

Journal Article Cochrane Database Syst Rev · February 15, 2012 BACKGROUND: Migraine is a common neurovascular disorder characterized by recurrent episodes of disabling headache, autonomic nervous system dysfunction, and, in some patients, neurological aura symptoms. Sumatriptan is one of a class of selective serotonin ... Full text Link to item Cite

Symptomatic oxygen for non-hypoxaemic chronic obstructive pulmonary disease.

Journal Article Cochrane Database Syst Rev · June 15, 2011 BACKGROUND: Dyspnoea is a common symptom in chronic obstructive pulmonary disease (COPD). People who are hypoxaemic may be given long-term oxygen relief therapy (LTOT) to improve their life expectancy and quality of life. However, the symptomatic benefit o ... Full text Link to item Cite

Systematic review: reliability of compendia methods for off-label oncology indications.

Journal Article Ann Intern Med · March 3, 2009 BACKGROUND: The Centers for Medicare & Medicaid Services limit coverage of cancer drugs for off-label indications to indications listed in specified compendia. PURPOSE: To assess whether compendia provide comprehensive, research-based, and timely informati ... Full text Link to item Cite

Efficacy of sedation regimens to facilitate mechanical ventilation in the pediatric intensive care unit: a systematic review.

Journal Article Pediatr Crit Care Med · March 2009 OBJECTIVE: Children admitted to pediatric intensive care units (PICUs) often receive sedatives to facilitate mechanical ventilation. However, despite their widespread use, data supporting appropriate dosing, safety, and optimal regimens for sedation during ... Full text Link to item Cite

The science of continuing medical education: Terms, tools, and gaps

Journal Article Chest · 2009 Background: By its synthesis of a selected portion of the continuing medical education (CME) literature, the evidence-based practice center (EPC) review discovered several major issues in primary study design and in the systematic review process of CME stu ... Full text Cite

Systematic review of CT and MR perfusion imaging for assessment of acute cerebrovascular disease.

Journal Article AJNR Am J Neuroradiol · September 2008 BACKGROUND AND PURPOSE: Perfusion imaging sequences are an important part of imaging studies designed to provide information to guide therapy for treatment of cerebrovascular disease. The purpose of this study was to perform a meta-analysis of the medical ... Full text Link to item Cite

Effectiveness of assisted reproductive technology (ART).

Journal Article Evid Rep Technol Assess (Full Rep) · May 2008 OBJECTIVES: We reviewed the evidence regarding the outcomes of interventions used in ovulation induction, superovulation, and in vitro fertilization (IVF) for the treatment of infertility. Short-term outcomes included pregnancy, live birth, multiple gestat ... Link to item Cite

Oxygen for relief of dyspnoea in mildly- or non-hypoxaemic patients with cancer: a systematic review and meta-analysis.

Journal Article Br J Cancer · January 29, 2008 The aim of this study was to determine the efficacy of palliative oxygen for relief of dyspnoea in cancer patients. MEDLINE and EMBASE were searched for randomised controlled trials, comparing oxygen and medical air in cancer patients not qualifying for ho ... Full text Open Access Link to item Cite

Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertension.

Journal Article Ann Intern Med · January 1, 2008 BACKGROUND: The relative effectiveness of angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) for lowering blood pressure is unknown. PURPOSE: To compare the benefits and harms of ACE inhibitors versus ARBs for treati ... Full text Link to item Cite

Review of evidence for genetic testing for CYP450 polymorphisms in management of patients with nonpsychotic depression with selective serotonin reuptake inhibitors.

Journal Article Genet Med · December 2007 PURPOSE: Cytochrome P450 (CYP450) enzymes metabolize selective serotonin reuptake inhibitor (SSRI) drugs used in treatment of depression. Variants in these genes may impact treatment efficacy and tolerability. The purpose of this study was 2-fold: to syste ... Full text Link to item Cite

Assessing the quality of colorectal cancer care: do we have appropriate quality measures? (A systematic review of literature).

Journal Article J Eval Clin Pract · December 2007 RATIONALE, AIMS AND OBJECTIVES: The burden of illness from colorectal cancer (CRC) can be reduced by improving the quality of care. Identifying appropriate quality measures is the first step in this direction. We identified process measures currently avail ... Full text Link to item Cite

Palliative oxygen for non-hypoxaemic chronic obstructive pulmonary disease

Journal Article Cochrane Database of Systematic Reviews · December 1, 2007 Full text Cite

Evidence for the treatment of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition).

Journal Article Chest · September 2007 BACKGROUND: The solitary pulmonary nodule (SPN) is a frequent incidental finding that may represent primary lung cancer or other malignant or benign lesions. The optimal management of the SPN remains unclear. METHODS: We conducted a systematic literature r ... Full text Link to item Cite

Physical examination tests for assessing a torn meniscus in the knee: a systematic review with meta-analysis.

Journal Article J Orthop Sports Phys Ther · September 2007 STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVES: To identify, analyze, and synthesize the literature to determine which physical examination tests, if any, accurately diagnose a torn tibial meniscus. BACKGROUND: Knee pain has a lifetime preva ... Full text Link to item Cite

Methodology for lung cancer evidence review and guideline development: ACCP evidence-based clinical practice guidelines (2nd Edition).

Journal Article Chest · September 2007 BACKGROUND: To assemble a geographically diverse panel of experts in the diagnosis and treatment of lung cancer, representative of multiple clinical specialties, with the intention of developing clinically relevant practice guidelines for chest medicine an ... Full text Link to item Cite

Noninvasive imaging for coronary artery disease: a technology assessment for the Medicare Coverage Advisory Commission.

Journal Article Am Heart J · February 2007 This report describes a review of the available scientific evidence through 2005 on direct noninvasive imaging tests (NITs) for coronary artery disease. In particular, the report addresses 6 key questions provided by the Agency for Healthcare Research and ... Full text Link to item Cite

Endoscopic ultrasound-guided fine-needle aspiration for non-small cell lung cancer staging: A systematic review and metaanalysis.

Journal Article Chest · February 2007 BACKGROUND: Endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) is a minimally invasive alternative technique for mediastinal staging of non-small cell lung cancer. A metaanalysis was performed to estimate the diagnostic accuracy of EUS-FNA for ... Full text Link to item Cite

Testing for cytochrome P450 polymorphisms in adults with non-psychotic depression treated with selective serotonin reuptake inhibitors (SSRIs).

Journal Article Evid Rep Technol Assess (Full Rep) · January 2007 OBJECTIVES: To determine if testing for cytochrome P450 (CYP450) polymorphisms in adults entering selective serotonin reuptake inhibitor (SSRI) treatment for non-psychotic depression leads to improvement in outcomes, or if testing results are useful in med ... Link to item Cite

Noninvasive staging of non-small cell lung cancer: ACCP evidenced-based clinical practice guidelines (2nd edition)

Journal Article Chest · 2007 Background: Correctly staging lung cancer is important because the treatment options and the prognosis differ significantly by stage. Several noninvasive imaging studies including chest CT scanning and positron emission tomography (PET) scanning are availa ... Full text Cite

Quality measures for the use of adjuvant chemotherapy and radiation therapy in patients with colorectal cancer: a systematic review.

Journal Article Cancer · November 15, 2006 BACKGROUND: Chemotherapy (CT) and radiation therapy (RT) are essential components of adjuvant (preoperative or postoperative) therapy for many patients with colorectal cancer (CRC); however, quality measures (QMs) of these critical aspects of CRC treatment ... Full text Link to item Cite

Genomic tests for ovarian cancer detection and management.

Journal Article Evid Rep Technol Assess (Full Rep) · October 2006 OBJECTIVES: To assess the evidence that the use of genomic tests for ovarian cancer screening, diagnosis, and treatment leads to improved outcomes. DATA SOURCES: PubMed and reference lists of recent reviews. REVIEW METHODS: We evaluated tests for: (a) sing ... Link to item Cite

Does this patient with headache have a migraine or need neuroimaging?

Journal Article JAMA · September 13, 2006 CONTEXT: In assessing the patient with headache, clinicians are often faced with 2 important questions: Is this headache a migraine? Does this patient require neuroimaging? The diagnosis of migraine can direct therapy, and information obtained from the his ... Full text Link to item Cite

Quality measures for the diagnosis and management of colorectal cancer.

Journal Article J Clin Oncol · June 20, 2006 16031 Background: The huge burden of illness from colorectal cancer (CRC) can be reduced by improving the quality of care for CRC patients. Identifying appropriate quality measures that can assess the processes of care is the first step in this process. Th ... Link to item Cite

Cancer care quality measures: diagnosis and treatment of colorectal cancer.

Journal Article Evid Rep Technol Assess (Full Rep) · May 2006 OBJECTIVES: To identify measures that are currently available to assess the quality of care provided to patients with colorectal cancer (CRC), and to assess the extent to which these measures have been developed and tested. DATA SOURCES: Published and unpu ... Link to item Cite

Management of adnexal mass.

Journal Article Evid Rep Technol Assess (Full Rep) · February 2006 OBJECTIVES: To assess diagnostic strategies for distinguishing benign from malignant adnexal masses. DATA SOURCES: MEDLINE(R) and reference lists of recent reviews; discharge data from the Nationwide Inpatient Sample. REVIEW METHODS: The major diagnostic m ... Link to item Cite

Methodology and grading of the evidence for the diagnosis and management of cough: ACCP evidence-based clinical practice guidelines.

Journal Article Chest · January 2006 OBJECTIVES: To assemble a multidisciplinary, geographically diverse panel of experts in the diagnosis and treatment of cough with the intention of developing clinically relevant practice guidelines for pulmonary and primary care physicians, including recom ... Full text Link to item Cite

The use of multiattribute decision models in evaluating triptan treatment options in migraine.

Journal Article J Neurol · September 2005 BACKGROUND: The physician treating patients with migraine is now able to choose from among seven triptans-almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan and zolmitriptan. These differ, to greater or lesser degrees, on a range ... Full text Link to item Cite

Dissemination of Evidence-based Practice Center reports.

Journal Article Ann Intern Med · June 21, 2005 The Evidence-based Practice Center (EPC) program within the Agency for Healthcare Research and Quality (AHRQ) provides detailed evidence reports for partner organizations that they can translate into activities that improve patient care. A review of these ... Full text Link to item Cite

Outcome measurement in behavioral headache research: headache parameters and psychosocial outcomes.

Journal Article Headache · May 2005 The experience of pain is complex and includes multiple dimensions or aspects, such as sensory and affective (among others). Headache includes not only pain, but also associated symptoms that can further diversify the relevant dimensions. Subjective rating ... Full text Link to item Cite

Guidelines for trials of behavioral treatments for recurrent headache, first edition: American Headache Society Behavioral Clinical Trials Workgroup.

Journal Article Headache · May 2005 Guidelines for design of clinical trials evaluating behavioral headache treatments were developed to facilitate production of quality research evaluating behavioral therapies for management of primary headache disorders. These guidelines were produced by a ... Full text Link to item Cite

Methodological issues in systematic reviews of headache trials: adapting historical diagnostic classifications and outcome measures to present-day standards.

Journal Article Headache · May 2005 Featured Publication Recent efforts to make headache diagnostic classification and clinical trial methodology more consistent provide valuable advice to trialists generating new evidence on effectiveness of treatments for headache; however, interpreting older trials that do no ... Full text Link to item Cite

Behavioral headache treatment: history, review of the empirical literature, and methodological critique.

Journal Article Headache · May 2005 Theoretical developments and burgeoning research on stress and illness in the mid-20th century yielded the foundations necessary to conceptualize headache as a psychophysiological disorder and eventually to develop and apply contemporary behavioral headach ... Full text Link to item Cite

Efficacy and effectiveness approaches in behavioral treatment trials.

Journal Article Headache · May 2005 The objective is to clarify the distinction between efficacy and effectiveness approaches and to discuss how these approaches can be used in a complementary way in the development, evaluation, and implementation of behavioral treatments for primary headach ... Full text Link to item Cite

Cost of multiple sclerosis by level of disability: a review of literature.

Journal Article Mult Scler · April 2005 We performed a review of the economic literature to identify what is known about the relationship between Expanded Disability Status Scale (EDSS) categories and cost of multiple sclerosis (MS). We sought cohort studies of patients with multiple sclerosis t ... Full text Link to item Cite

How treatment priorities influence triptan preferences in clinical practice: perspectives of migraine sufferers, neurologists, and primary care physicians.

Journal Article Curr Med Res Opin · March 2005 BACKGROUND: In treating migraine sufferers, physicians can choose from among seven triptans with different attributes. OBJECTIVE: To develop a system for selecting an oral triptan based on treatment priorities of migraine sufferers, neurologists, and prima ... Full text Link to item Cite

Measures of physical and cognitive function and work status among individuals with multiple sclerosis: a review of the literature.

Journal Article J Occup Rehabil · March 2005 The purpose of this review was to critically evaluate the multiple sclerosis (MS) literature that has examined physical and cognitive function in relation to ability to work. Although numerous factors may be considered when determining work ability, physic ... Full text Link to item Cite

Prioritizing treatment attributes and their impact on selecting an oral triptan: results from the TRIPSTAR Project.

Journal Article Curr Pain Headache Rep · December 2004 Seven oral triptans, which differ on a range of attributes important for treatment selection, are now available for treating migraine. US neurologists were surveyed to assess the relative importance of treatment attributes, prespecified by clinical relevan ... Full text Link to item Cite

Selecting the preferred triptans

Journal Article Journal of Headache and Pain · December 1, 2004 The objective was to identify a subset of preferred triptans from among available agents. A criterion of dominance was applied to statistically significant differences which emerged from a recent meta-analysis of placebo-controlled trials of the oral tript ... Full text Cite

TRIPSTAR: prioritizing oral triptan treatment attributes in migraine management.

Journal Article Acta Neurol Scand · September 2004 Migraine can be associated with severe pain and is often very disabling. Optimal treatment should provide rapid and sustained, complete pain relief, be well tolerated and restore normal function. The seven commercially available triptans show differences i ... Full text Link to item Cite

Priorities for triptan treatment attributes and the implications for selecting an oral triptan for acute migraine: a study of US primary care physicians (the TRIPSTAR Project).

Journal Article Clin Ther · September 2004 BACKGROUND: Physicians treating patients with migraine can now choose from among 7 triptans, which differ on a range of attributes that may be important for treatment selection. OBJECTIVE: The aims of this study were to determine the relative importance of ... Full text Link to item Cite

Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.

Journal Article Chest · July 2004 Although idiopathic pulmonary arterial hypertension is perceived as a progressive disease with a uniformly poor outcome, the natural history of disease is heterogeneous, with some patients dying within months of diagnosis and others living for decades. The ... Full text Link to item Cite

Methodology and grading for pulmonary hypertension evidence review and guideline development.

Journal Article Chest · July 2004 The American College of Chest Physicians assembled a multidisciplinary, geographically diverse panel of experts in the treatment of pulmonary hypertension to develop clinically relevant practice guidelines for the diagnosis and treatment of pulmonary hyper ... Full text Link to item Cite

Screening, early detection, and diagnosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.

Journal Article Chest · July 2004 Pulmonary arterial hypertension (PAH) occurs as an idiopathic process or as a component of a variety of disease processes, including chronic thromboembolic disease, connective tissue diseases, congenital heart disease, and exposure to exogenous factors inc ... Full text Link to item Cite

Medical therapy for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.

Journal Article Chest · July 2004 Pulmonary arterial hypertension (PAH) is often difficult to diagnose and challenging to treat. Untreated, it is characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and death. The past decade has see ... Full text Link to item Cite

Surgical treatments/interventions for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines.

Journal Article Chest · July 2004 While considerable advances have been achieved in the medical treatment of pulmonary arterial hypertension (PAH) over the past decade, surgical and interventional approaches continue to have important roles in those patients for whom medical therapy is una ... Full text Link to item Cite

Pulmonary artery hypertension and sleep-disordered breathing: ACCP evidence-based clinical practice guidelines.

Journal Article Chest · July 2004 The objective of this article is to review the available data on the relationship between sleep-disordered breathing (SDB) and pulmonary arterial hypertension (PAH), with a focus on the prevalence of SDB in patients with idiopathic PAH (IPAH); the prevalen ... Full text Link to item Cite

Criteria to determine disability related to multiple sclerosis.

Journal Article Evid Rep Technol Assess (Summ) · May 2004 Link to item Cite

Alzheimer disease: operating characteristics of PET--a meta-analysis.

Journal Article Radiology · April 2004 PURPOSE: To assess the operating characteristics of positron emission tomography (PET) by using fluorine 18 fluorodeoxyglucose (FDG) in the diagnosis of Alzheimer disease. MATERIALS AND METHODS: Articles published between 1989 and 2003 were identified in t ... Full text Link to item Cite

The economic burden of allergic rhinitis: a critical evaluation of the literature.

Journal Article Pharmacoeconomics · 2004 Although a large number of economic analyses of allergic rhinitis have been published, there are relatively few empirically based studies, particularly outside the US. The majority of these analyses can be classified as burden-of-illness studies. Most esti ... Full text Link to item Cite

Oral sumatriptan for acute migraine

Journal Article Praxis · 2004 Full text Cite

PNP14: COST OF MULTIPLE SCLEROSIS BY LEVEL OF DISABILITY

Journal Article Value in Health · May 2003 Full text Cite

Ergotamine and dihydroergotamine: history, pharmacology, and efficacy.

Journal Article Headache · February 2003 Ergotamine and dihydroergotamine share structural similarities with the adrenergic, dopaminergic, and serotonergic neurotransmitters. As a result, they have wide-ranging effects on the physiologic processes that they mediate. Ergotamine and dihydroergotami ... Full text Link to item Cite

Performance characteristics of different modalities for diagnosis of suspected lung cancer: summary of published evidence.

Journal Article Chest · January 2003 STUDY OBJECTIVES: To determine the test performance characteristics of various modalities for the diagnosis of suspected lung cancer. DESIGN, SETTING, AND PARTICIPANTS: A systematic search of MEDLINE, HealthStar, and Cochrane Library databases to July 2001 ... Full text Link to item Cite

Noninvasive staging of non-small cell lung cancer: a review of the current evidence.

Journal Article Chest · January 2003 STUDY OBJECTIVES: To determine the test performance characteristics of CT scanning, positron emission tomography (PET) scanning, MRI, and endoscopic ultrasound (EUS) for staging the mediastinum, and to evaluate the accuracy of the clinical evaluation (ie, ... Full text Link to item Cite

Invasive staging of non-small cell lung cancer: a review of the current evidence.

Journal Article Chest · January 2003 STUDY OBJECTIVES: To determine the test performance characteristics of transbronchial needle aspiration (TBNA), transthoracic needle aspiration (TTNA), endoscopic ultrasound-guided needle aspiration (EUS-NA), and mediastinoscopy in staging non-small cell l ... Full text Link to item Cite

Assessment of the scope and quality of clinical practice guidelines in lung cancer.

Journal Article Chest · January 2003 Featured Publication STUDY OBJECTIVES: To provide an evidence-based background for developing the American College of Chest Physicians (ACCP) lung cancer guidelines, a systematic review of the literature was performed to identify published lung cancer guidelines and evaluate t ... Full text Link to item Cite

Prevention of lung cancer: summary of published evidence.

Journal Article Chest · January 2003 STUDY OBJECTIVES: To describe empiric research related to lung cancer prevention strategies, including chemoprevention aimed at reducing lung cancer incidence and various smoking avoidance and cessation interventions aimed at reducing smoking rates. DESIGN ... Full text Link to item Cite

Oral sumatriptan for acute migraine.

Journal Article Cochrane Database Syst Rev · 2003 Featured Publication BACKGROUND: Migraine is a common neurovascular disorder characterized by recurrent episodes of disabling headache, autonomic nervous system dysfunction, and, in some patients, neurological aura symptoms. Sumatriptan is one of a class of selective serotonin ... Full text Link to item Cite

Screening for lung cancer: a review of the current literature.

Journal Article Chest · January 2003 STUDY OBJECTIVES: To review the available data on the early detection of lung cancer, with a focus on three technologies: chest x-ray (CXR), sputum cytology, and low-dose CT (LDCT) scanning. DESIGN, SETTING, PARTICIPANTS: Review of published clinical studi ... Full text Link to item Cite

Overview of methodology for lung cancer evidence review and guideline development.

Journal Article Chest · January 2003 A multidisciplinary panel was convened by the American College of Chest Physicians (ACCP) to develop clinical practice guidelines for lung cancer prevention, diagnosis, and treatment. The ACCP Expert Panel on Lung Cancer Guidelines produced 20 guidelines, ... Full text Link to item Cite

Management of allergic rhinitis in the working-age population.

Journal Article Evid Rep Technol Assess (Summ) · January 2003 Link to item Cite

Gastroenterologist specialist care and care provided by generalists--an evaluation of effectiveness and efficiency.

Journal Article Am J Gastroenterol · January 2003 OBJECTIVE: In this era of cost containment, gastroenterologists must demonstrate that they provide effective and efficient care. The aim of this study was to evaluate the process and outcomes of care provided by gastroenterologists and generalist physician ... Full text Link to item Cite

When should functional neuroimaging techniques be used in the diagnosis and management of Alzheimer's dementia? A decision analysis.

Journal Article Value Health · 2003 BACKGROUND: Functional neuroimaging, including positron emission tomography (PET), has been proposed for use in diagnosing Alzheimer's disease-related dementia (AD). OBJECTIVE: The objective of this study was identify the circumstances under which PET scan ... Full text Link to item Cite

Screening for lung cancer: A review of the current literature

Journal Article Chest · January 1, 2003 Study objectives: To review the available data on the early detection of lung cancer, with a focus on three technologies: chest x-ray (CXR), sputum cytology, and low-dose CT (LDCT) scanning. Design, setting, participants: Review of published clinical studi ... Cite

Prevention of lung cancer: Summary of published evidence

Journal Article Chest · January 1, 2003 Study objectives: To describe empiric research related to lung cancer prevention strategies, including chemoprevention aimed at reducing lung cancer incidence and various smoking avoidance and cessation interventions aimed at reducing smoking rates. Design ... Cite

Invasive staging of non-small cell lung cancer: A review of the current evidence

Journal Article Chest · January 1, 2003 Study objectives: To determine the test performance characteristics of transbronchial needle aspiration (TBNA), transthoracic needle aspiration (TTNA), endoscopic ultrasound-guided needle aspiration (EUS-NA), and mediastinoscopy in staging non-small cell l ... Cite

Performance characteristics of different modalities for diagnosis of suspected lung cancer: Summary of published evidence

Journal Article Chest · January 1, 2003 Study objectives: To determine the test performance characteristics of various modalities for the diagnosis of suspected lung cancer. Design, setting, and participants: A systematic search of MEDLINE, HealthStar, and Cochrane Library databases to July 2001 ... Cite

Noninvasive staging of non-small cell lung cancer: A review of the current evidence

Journal Article Chest · January 1, 2003 Study objectives: To determine the test performance characteristics of CT scanning, positron emission tomography (PET) scanning, MRI, and endoscopic ultrasound (EUS) for staging the mediastinum, and to evaluate the accuracy of the clinical evaluation (ie, ... Cite

Immunization and MS: a summary of published evidence and recommendations.

Journal Article Neurology · December 24, 2002 Featured Publication OBJECTIVE: To review the risk of MS exacerbations after infectious episodes potentially preventable by vaccination, and the risks and benefits of immunizing patients with MS. METHODS: The authors searched MEDLINE (1966 to January 2001; U.S. National Librar ... Full text Link to item Cite

Management of uterine leiomyomata: what do we really know?

Journal Article Obstet Gynecol · July 2002 OBJECTIVE: To systematically review the literature on the surgical and nonsurgical management of uterine leiomyomata. DATA SOURCES: Published literature in English on the management of uterine leiomyomata published from 1975 through 2000 was identified in ... Full text Link to item Cite

Management of prolonged pregnancy.

Journal Article Evid Rep Technol Assess (Summ) · March 2002 Link to item Cite

Anti-cholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease.

Journal Article Cochrane Database Syst Rev · 2002 BACKGROUND: Inhaled bronchodilators form the mainstay of treatment for acute exacerbations of COPD. Two types of agent are used routinely, either singly or in combination: anticholinergic agents and beta2-sympathomimetic agonists. OBJECTIVES: To assess the ... Full text Link to item Cite

Use of data from nonrandomized trial designs in evidence reports: an application to treatment of pulmonary disease following spinal cord injury.

Journal Article J Rehabil Res Dev · 2002 Featured Publication Evidence reports summarize the evidence pertaining to various health-related topics. Including evidence from nonrandomized studies into such reports involves a trade-off between availability and bias. We describe a general framework by which information fr ... Link to item Cite

Short-term trials and long-term effects.

Journal Article Science · September 28, 2001 Full text Link to item Cite

Short-term trials and long-term effects - Response

Journal Article SCIENCE · September 28, 2001 Link to item Cite

Reply

Journal Article Cephalalgia · July 2001 Full text Cite

Treatment of pulmonary disease following cervical spinal cord injury.

Journal Article Evid Rep Technol Assess (Summ) · June 2001 Link to item Cite

Management of acute exacerbations of chronic obstructive pulmonary disease: a summary and appraisal of published evidence.

Journal Article Ann Intern Med · April 3, 2001 PURPOSE: To review critically the available data on diagnostic evaluation, risk stratification, and therapeutic management of patients with acute exacerbations of chronic obstructive pulmonary disease (COPD). DATA SOURCES: English-language articles were id ... Full text Link to item Cite

Management of acute exacerbations of COPD: a summary and appraisal of published evidence.

Journal Article Chest · April 2001 Featured Publication STUDY OBJECTIVES: To critically review the available data on the diagnostic evaluation, risk stratification, and therapeutic management of patients with acute exacerbations of COPD. DESIGN, SETTING, AND PARTICIPANTS: English-language articles were identifi ... Full text Link to item Cite

Inhaled short-acting beta2-agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease.

Journal Article Cochrane Database Syst Rev · 2001 Featured Publication BACKGROUND: Inhaled short acting beta2 adrenergic agonists and ipratropium bromide are both used in the treatment of acute exacerbations of chronic obstructive pulmonary disease. OBJECTIVES: In patients with acute exacerbations of COPD to: 1. To assess the ... Full text Link to item Cite

Butalbital in the treatment of headache: history, pharmacology, and efficacy.

Journal Article Headache · 2001 Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patient ... Full text Link to item Cite

Management of uterine fibroids.

Journal Article Evid Rep Technol Assess (Summ) · January 2001 Link to item Cite

Opioid chronopharmacology [2] (multiple letters)

Journal Article Cephalalgia · 2001 Cite

Opioids.

Journal Article Cephalalgia · December 2000 Full text Link to item Cite

Setting the target for a better cervical screening test: characteristics of a cost-effective test for cervical neoplasia screening.

Journal Article Obstet Gynecol · November 2000 OBJECTIVE: To determine the potential effects on costs and outcomes of changes in sensitivity and specificity with new screening methods for cervical cancer. METHODS: Using a Markov model of the natural history of cervical cancer, we estimated the effects ... Full text Link to item Cite

Management of acute exacerbations of chronic obstructive pulmonary disease.

Journal Article Evid Rep Technol Assess (Summ) · September 2000 Link to item Cite

Mathematical model for the natural history of human papillomavirus infection and cervical carcinogenesis.

Journal Article Am J Epidemiol · June 15, 2000 The authors constructed a Markov model as part of a systematic review of cervical cytology conducted at the Duke University Evidence-based Practice Center (Durham, North Carolina) between October 1997 and September 1998. The model incorporated states for h ... Full text Link to item Cite

Accuracy of the Papanicolaou test in screening for and follow-up of cervical cytologic abnormalities: a systematic review.

Journal Article Ann Intern Med · May 16, 2000 Featured Publication PURPOSE: To evaluate the accuracy of conventional and new methods of Papanicolaou (Pap) testing when used to detect cervical cancer and its precursors. DATA SOURCES: Systematic search of English-language literature through October 1999 using MEDLINE, EMBAS ... Full text Link to item Cite

Evaluation of cervical cytology.

Journal Article Evid Rep Technol Assess (Summ) · January 1999 Link to item Cite

Getting meaningful informed consent from older adults: a structured literature review of empirical research.

Journal Article J Am Geriatr Soc · April 1998 OBJECTIVES: To perform a structured literature review of the published empirical research on informed consent with older adults in order to make recommendations to improve the informed consent process and to highlight areas needing further examination. DES ... Full text Link to item Cite

Influence of projected complication rates on estimated appropriate use rates for carotid endarterectomy. Appropriateness Project Investigators. Academic Medical Center Consortium.

Journal Article Health Serv Res · August 1997 OBJECTIVE: To examine specifically the influence of estimated perioperative mortality and stroke rate on the assessment of appropriateness of carotid endarterectomy. DATA SOURCES/STUDY SETTING: An expert panel convened to rate the appropriateness of a vari ... Link to item Cite

Influence of projected complication rates on estimated appropriate use rates for carotid endarterectomy

Journal Article Health Services Research · August 1, 1997 Objective. To examine specifically the influence of estimated perioperative mortality and stroke rate on the assessment of appropriateness of carotid endarterectomy. Data Sources/Study Setting. An expert panel convened to rate the appropriateness of a vari ... Cite

Treatment considerations for persons with metastatic prostate cancer: survival versus out-of-pocket costs.

Journal Article Urology · February 1997 OBJECTIVES: Treatment decisions for metastatic prostate cancer require the consideration of factors such as survival, quality of life, costs of care, and toxicities. In this study, we queried physicians who had extensive experience with prostate cancer abo ... Full text Link to item Cite

Cost-effective models for flutamide for prostate carcinoma patients: are they helpful to policy makers?

Journal Article Cancer · May 1, 1996 BACKGROUND: More than 50,000 male patients received hormonal therapy for metastatic prostate carcinoma in 1995. Nonsteroidal antiandrogens, such as flutamide, when used in conjunction with castration, are effective in prolonging the time to progression of ... Full text Link to item Cite

Stroke prevention: the emerging strategies.

Journal Article Hosp Pract (1995) · March 15, 1996 Warfarin prophylaxis in patients with nonvalvular atrial fibrillation may be one of the most valuable public-health interventions. Barriers to its optimal utilization include wariness about bleeding complications and concern about age-related sensitivity t ... Link to item Cite

Comparison and meta-analysis of randomized trials of endarterectomy for symptomatic carotid artery stenosis.

Journal Article Neurology · November 1995 OBJECTIVE: Comparison and meta-analysis of randomized trials of carotid endarterectomy for symptomatic stenosis of the extracranial carotid artery. BACKGROUND: Randomized trials (North American Symptomatic Carotid Endarterectomy Trial [NASCET], the Europea ... Full text Link to item Cite

Physician attitudes about anticoagulation for nonvalvular atrial fibrillation in the elderly.

Journal Article Arch Intern Med · February 13, 1995 BACKGROUND: Our goal was to determine whether patient age affects a physician's reported likelihood of using anticoagulant therapy or the intensity of anticoagulant therapy for patients with nonvalvular atrial fibrillation. METHODS: We surveyed a nationwid ... Link to item Cite

MEDICAL-TREATMENT OF STROKE PREVENTION (VOL 121, PG 41, 1994)

Journal Article ANNALS OF INTERNAL MEDICINE · 1995 Cite

Meta-analytic tools for medical decision making: a practical guide.

Journal Article Med Decis Making · 1995 This paper is an extension of notes used for the short course in meta-analysis given at the 13th and 14th annual meetings of the Society for Medical Decision Making. The material covers both standard and evolving methods of meta-analysis. The methods inclu ... Full text Link to item Cite

Performance of the serum cobalamin assay for diagnosis of cobalamin deficiency.

Journal Article Am J Med Sci · November 1994 The authors' objective, with this study, was to determine the use in routine clinical practice of the cobalamin serum assay in evaluating patients suspected of having cobalamin deficiency. The design was a prospective observational study of a diagnostic te ... Full text Link to item Cite

Correction: Error in Dosage

Journal Article Annals of Internal Medicine · September 15, 1994 Full text Cite

Management of atrial fibrillation.

Journal Article Ann Intern Med · September 15, 1994 Full text Link to item Cite

Medical treatment for stroke prevention.

Journal Article Ann Intern Med · July 1, 1994 PURPOSE: To review the effectiveness of medical treatments for stroke prevention in patients at elevated risk for stroke. DATA SOURCES: English-language articles published after 1977 and indexed in MEDLINE under the following Medical Subject Heading terms: ... Full text Link to item Cite

Multicenter review of preoperative risk factors for carotid endarterectomy in patients with ipsilateral symptoms.

Journal Article Stroke · June 1994 BACKGROUND AND PURPOSE: Randomized clinical trials have shown that carotid endarterectomy decreases the risk of subsequent stroke in patients with high-grade carotid stenosis and ipsilateral transient ischemic attack or minor stroke. The benefit of surgery ... Full text Link to item Cite

Response

Journal Article Stroke · January 1, 1994 Cite

GUIDELINES FOR MEDICAL-TREATMENT FOR STROKE PREVENTION

Journal Article ANNALS OF INTERNAL MEDICINE · 1994 Cite

Predicting complications of carotid endarterectomy.

Journal Article Stroke · September 1993 BACKGROUND AND PURPOSE: Carotid endarterectomy has been shown to be beneficial in patients with high-grade carotid stenosis and ipsilateral transient ischemic attack or stroke. This benefit will be realized only if the operation is performed safely. We sou ... Full text Link to item Cite

The effect of sleeved arms on oscillometric blood pressure measurement.

Journal Article J Gen Intern Med · June 1993 The authors measured the blood pressures of 36 subjects who had bare and sleeved arms to determine the effect of wearing sleeves on automatic oscillometric blood pressure measurements. They found no statistically significant effect of sleeves on the measur ... Full text Link to item Cite