Scholars@Duke
John Kevin Harrison

John Kevin Harrison

Professor of Medicine
Medicine, Cardiology
harri015@mc.duke.edu
Duke Box 3331, Durham, NC 27710
7624B Hosp North, Durham, NC

Selected Publications

Real-World Outcomes for the Fifth-Generation Balloon Expandable Transcatheter Heart Valve in the United States.

Journal Article JACC Cardiovasc Interv · April 22, 2024 BACKGROUND: The fifth-generation SAPIEN 3 Ultra Resilia valve (S3UR) incorporates several design changes as compared with its predecessors, the SAPIEN 3 (S3) and SAPIEN 3 Ultra (S3U) valves, including bovine leaflets treated with a novel process intended t ... Full text Link to item Cite

Infarct exclusion repair of postmyocardial infarction ventricular septal rupture with a hybrid patch and septal occluder device compared with patch only.

Conference JTCVS Tech · December 2023 OBJECTIVE: We developed a hybrid technique for repairing post-myocardial infarction (MI) ventricular septal defect (VSD) that combines infarct exclusion with patch and a nitinol-mesh septal occluder device (SOD) to provide a scaffold to support the damaged ... Full text Link to item Cite

Improving patient outcomes with a mobile digital health platform for patients undergoing transcatheter aortic valve replacement.

Journal Article J Invasive Cardiol · September 2023 PURPOSE: ManageMySurgery (MMS) is a digital health application (app) for patients undergoing surgery, including Transcatheter Aortic Valve Replacement (TAVR). Patients using MMS review procedure-specific education, view FAQs, and report patient-reported ou ... Full text Link to item Cite

3-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis.

Journal Article Journal of the American College of Cardiology · May 2023 BackgroundRandomized data comparing outcomes of transcatheter aortic valve replacement (TAVR) with surgery in low-surgical risk patients at time points beyond 2 years is limited. This presents an unknown for physicians striving to educate patients ... Full text Cite

Feasibility study of a novel digital health platform for patients undergoing transcatheter aortic valve replacement.

Journal Article J Card Surg · July 2022 INTRODUCTION: Despite abundant evidence indicating that digital health solutions improve outcomes in chronic medical conditions, there are few validated solutions for acute surgical episodes. Transcatheter aortic valve replacement (TAVR) is a less invasive ... Full text Link to item Cite

Surgical Sutureless and Sutured Aortic Valve Replacement in Low-risk Patients.

Journal Article Ann Thorac Surg · February 2022 BACKGROUND: Randomized clinical trials have shown that transcatheter aortic valve replacement is noninferior to surgery in low surgical risk patients. We compared outcomes in patients treated with a sutured (stented or stentless) or sutureless surgical val ... Full text Link to item Cite

Five-Year Clinical and Quality of Life Outcomes From the CoreValve US Pivotal Extreme Risk Trial.

Journal Article Circ Cardiovasc Interv · June 2021 BACKGROUND: Older adults with comorbidities who are at extreme risk for surgical aortic valve replacement may be appropriate candidates for transcatheter aortic valve replacement (TAVR). We present the 5-year clinical, echocardiographic, and health status ... Full text Link to item Cite

Variation in Antithrombotic Therapy and Clinical Outcomes in Patients With Preexisting Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement: Insights From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.

Journal Article Circ Cardiovasc Interv · April 2021 BACKGROUND: Optimal antithrombotic management of patients with preexisting atrial fibrillation undergoing transcatheter aortic valve replacement is challenging given the need to balance the risk of bleeding and thromboembolism. We aimed to examine variatio ... Full text Link to item Cite

Geographic Access to Transcatheter Aortic Valve Replacement Centers in the United States: Insights From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.

Journal Article JAMA Cardiol · June 10, 2020 Importance: Geographic access to transcatheter aortic replacement (TAVR) centers varies in the United States as a result of controlled expansion through minimum volume requirements. Objective: To describe the current geographic access to TAVR centers in th ... Full text Link to item Cite

Transcatheter aortic valve replacement for patients with severe bicuspid aortic stenosis.

Journal Article Am Heart J · June 2020 BACKGROUND: Patients with bicuspid aortic valve stenosis (BAV) were excluded from all the trileaflet aortic valve stenosis (TAV) pivotal trials, and therefore, their outcomes are not clearly defined. The aim of the study was to evaluate the outcomes of tra ... Full text Link to item Cite

Outcomes of Transcatheter Aortic Valve Replacement in Patients With Bicuspid Aortic Valve Disease: A Report From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.

Journal Article Circulation · March 31, 2020 BACKGROUND: Patients with bicuspid aortic valve (AV) stenosis were excluded from the pivotal evaluations of transcatheter AV replacement (TAVR) devices. We sought to evaluate the outcomes of TAVR in patients with bicuspid AV stenosis in comparison with tho ... Full text Link to item Cite

Complete 2-Year Results Confirm Bayesian Analysis of the SURTAVI Trial.

Journal Article JACC Cardiovasc Interv · February 10, 2020 OBJECTIVES: The aim of this study was to report the 2-year results of the SURTAVI (Surgical Replacement and Transcatheter Aortic Valve Implantation) trial and confirm the interim Bayesian analysis. BACKGROUND: Transcatheter aortic valve replacement (TAVR) ... Full text Link to item Cite

Incidence, Temporal Trends, and Associated Outcomes of Vascular and Bleeding Complications in Patients Undergoing Transfemoral Transcatheter Aortic Valve Replacement: Insights From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapies Registry.

Journal Article Circ Cardiovasc Interv · January 2020 BACKGROUND: Vascular and bleeding complications were commonly reported in transcatheter aortic valve replacement clinical trials. Little is known about complication rates in contemporary US clinical practice or clinical outcomes associated with these compl ... Full text Link to item Cite

To Double Stick or Not to Double Stick?

Journal Article JACC Cardiovasc Interv · November 11, 2019 Full text Link to item Cite

Factors Associated With and Outcomes of Aborted Procedures During Elective Transcatheter Aortic Valve Replacement.

Journal Article JACC Cardiovasc Interv · September 23, 2019 OBJECTIVES: This study sought to evaluate the outcomes and factors associated with aborted procedures among patients undergoing elective transcatheter aortic valve replacement (TAVR). BACKGROUND: Elective TAVR procedures can be aborted because of device li ... Full text Link to item Cite

Incidence and Outcomes of Surgical Bailout During TAVR: Insights From the STS/ACC TVT Registry.

Journal Article JACC Cardiovasc Interv · September 23, 2019 OBJECTIVES: The aim of this study was to evaluate the incidence and outcomes of surgical bailout during transcatheter aortic valve replacement (TAVR). BACKGROUND: The incidence and outcomes of unplanned conversion to open heart surgery, or "surgical bailou ... Full text Link to item Cite

Relation of Postdischarge Care Fragmentation and Outcomes in Transcatheter Aortic Valve Implantation from the STS/ACC TVT Registry.

Journal Article Am J Cardiol · September 15, 2019 Fragmented care following elective surgery has been associated with poor outcomes. The association between fragmented care and outcomes in patients undergoing transcatheter aortic valve implantation (TAVI) is unknown. We examined patients who underwent TAV ... Full text Link to item Cite

Trends and Outcomes of Alternative-Access Transcatheter Aortic Valve Replacement.

Journal Article J Invasive Cardiol · July 2019 BACKGROUND: Alternative access (AA) is still required for a significant proportion of patients undergoing transcatheter aortic valve replacement (TAVR). We sought to compare the clinical outcomes of patients undergoing AA vs transfemoral (TF) access. METHO ... Link to item Cite

Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation.

Journal Article J Am Coll Cardiol · May 21, 2019 BACKGROUND: The incidence of permanent pacemaker (PPM) implantation is higher following mitral valve surgery (MVS) with ablation for atrial fibrillation (AF) compared with MVS alone. OBJECTIVES: This study identified risk factors and outcomes associated wi ... Full text Link to item Cite

Identifying the Infarct-Related Artery in Patients With Non-ST-Segment-Elevation Myocardial Infarction.

Journal Article Circ Cardiovasc Interv · May 2019 BACKGROUND: Determining the infarct-related artery (IRA) in non-ST-segment-elevation myocardial infarction (MI) can be challenging. Delayed-enhancement cardiac magnetic resonance (DE-CMR) can accurately identify small MIs. The purpose of this study was to ... Full text Link to item Cite

5-Year Outcomes of Self-Expanding Transcatheter Versus Surgical Aortic Valve Replacement in High-Risk Patients.

Journal Article J Am Coll Cardiol · December 4, 2018 BACKGROUND: The CoreValve U.S. Pivotal High Risk Trial was the first randomized trial to show superior 1-year mortality of transcatheter aortic valve replacement (TAVR) compared with surgical aortic valve replacement (SAVR) among high operative mortality-r ... Full text Link to item Cite

Variation in post-TAVR antiplatelet therapy utilization and associated outcomes: Insights from the STS/ACC TVT Registry.

Journal Article Am Heart J · October 2018 BACKGROUND: Dual antiplatelet therapy (DAPT) is recommended following transcatheter aortic valve replacement (TAVR); however, the optimal antiplatelet strategy is undefined, and little is known about practice patterns. We aimed to describe contemporary pra ... Full text Link to item Cite

Incidence, Management, and Associated Clinical Outcomes of New-Onset Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: An Analysis From the STS/ACC TVT Registry.

Journal Article JACC Cardiovasc Interv · September 10, 2018 OBJECTIVES: The aim of this study was to evaluate incidence, care patterns, and clinical outcomes in patients developing new-onset atrial fibrillation (AF) following transcatheter aortic valve replacement (TAVR). BACKGROUND: Pre-procedural AF has been asso ... Full text Link to item Cite

Impact of Balloon Predilatation on Hemodynamics and Outcomes After Transcatheter Aortic Valve Implantation With the Self-Expanding CoreValve Prosthesis.

Journal Article Am J Cardiol · June 1, 2018 The impact of predilatation (Pre-Dil) on prosthesis hemodynamics and clinical outcomes of subjects who underwent transcatheter aortic valve implantation (TAVI) with a self-expanding prosthesis remains unclear. Two thousand seven hundred twenty-one subjects ... Full text Link to item Cite

Stroke and Cardiovascular Outcomes in Patients With Carotid Disease Undergoing Transcatheter Aortic Valve Replacement.

Journal Article Circ Cardiovasc Interv · June 2018 BACKGROUND: Stroke is a serious complication of both transcatheter aortic valve replacement (TAVR) and carotid artery disease (CD). The implications of CD in patients undergoing TAVR are unclear. METHODS AND RESULTS: The Society of Thoracic Surgeons and Am ... Full text Link to item Cite

Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study.

Journal Article J Thorac Cardiovasc Surg · April 2018 OBJECTIVE: To analyze patient risk factors and processes of care associated with secondary surgical-site infection (SSI) after coronary artery bypass grafting (CABG). METHODS: Data were collected prospectively between February and October 2010 for consenti ... Full text Link to item Cite

Treatment options for recurrent thromboembolism in patients with cryptogenic cerebrovascular events: Medical therapy versus device closure or surgical repair of patent foramen ovale

Chapter · January 1, 2018 Patent foramen ovale (PFO) is a cardiac anatomic structure frequently found in the general population, with an estimated prevalence of 25%-30%. PFO has been linked to increased risk for thromboembolism, including ischemic systemic and cerebrovascular event ... Full text Cite

Peripheral Artery Disease and Transcatheter Aortic Valve Replacement Outcomes: A Report From the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Therapy Registry.

Journal Article Circ Cardiovasc Interv · October 2017 BACKGROUND: Peripheral artery disease (PAD) is associated with increased cardiovascular mortality, and PAD risk factors overlap with those for aortic stenosis. The prevalence and outcomes associated with PAD in a population undergoing transcatheter aortic ... Full text Link to item Cite

Morbidity and Mortality Conference for Percutaneous Coronary Intervention.

Journal Article Circ Cardiovasc Qual Outcomes · August 2017 BACKGROUND: Morbidity and mortality conference is a common educational and quality improvement activity performed in cardiac catheterization laboratories, but best practices for case selection and for maximizing the effectiveness of peer review have not be ... Full text Link to item Cite

Assessment of Paravalvular Leak After Transcatheter Aortic Valve Replacement: Transesophageal Echocardiography Compared With Transthoracic Echocardiography.

Journal Article J Cardiothorac Vasc Anesth · August 2017 OBJECTIVES: Determine whether moderate or greater paravalvular leak (PVL) after transcatheter aortic valve replacement quantified using intraoperative transesophageal echocardiography (TEE) is associated with mortality and investigate the correlation betwe ... Full text Link to item Cite

Early Clinical Outcomes After Transcatheter Aortic Valve Replacement Using a Novel Self-Expanding Bioprosthesis in Patients With Severe Aortic Stenosis Who Are Suboptimal for Surgery: Results of the Evolut R U.S. Study.

Journal Article JACC Cardiovasc Interv · February 13, 2017 OBJECTIVES: This study sought to evaluate this transcatheter aortic valve (TAV) bioprosthesis in patients who are poorly suitable for surgical aortic valve (AV) replacement. BACKGROUND: A novel self-expandable TAV bioprosthesis was designed to provide a lo ... Full text Link to item Cite

Balloon Post-Dilation Following Implantation of a Self-Expanding Transcatheter Aortic Valve Bioprosthesis.

Journal Article JACC Cardiovasc Interv · January 23, 2017 OBJECTIVES: This study sought to explore the impact of balloon post-dilation (BPD) on outcomes in the CoreValve US Clinical Trials. BACKGROUND: BPD following transcatheter aortic valve replacement (TAVR) has been used in selected cases to optimize hemodyna ... Full text Link to item Cite

Resolution of severe hemolysis and paravalvular aortic regurgitation employing an Amplatzer Vascular Plug 4: the importance of detailed pre-procedural planning using CT angiography.

Journal Article Cardiovasc Interv Ther · January 2017 A 76-year-old woman presented with progressive heart failure and transfusion-dependent hemolytic anemia due to severe paravalvular aortic regurgitation 4 years after bioprosthetic aortic valve replacement. She was deemed not to be a candidate for redo card ... Full text Link to item Cite

Outcomes in the Randomized CoreValve US Pivotal High Risk Trial in Patients With a Society of Thoracic Surgeons Risk Score of 7% or Less.

Journal Article JAMA Cardiol · November 1, 2016 IMPORTANCE: Transcatheter aortic valve replacement (TAVR) is now a well-accepted alternative to surgical AVR (SAVR) for patients with symptomatic aortic stenosis at increased operative risk. There is interest in whether TAVR would benefit patients at lower ... Full text Link to item Cite

Safety and Efficacy of Self-Expanding TAVR in Patients With Aortoventricular Angulation.

Journal Article JACC Cardiovasc Imaging · August 2016 OBJECTIVES: The aim of this study was to determine the relationship between aortoventricular (AoV) angulation on clinical outcomes after self-expanding transcatheter aortic valve replacement (TAVR) in patients with severe aortic stenosis who were deemed su ... Full text Link to item Cite

Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunction.

Journal Article Eur Heart J · July 21, 2016 AIMS: We aimed to determine the frequency of aortic valve surgery (AVR) with or without coronary artery bypass grafting (CABG), among patients with moderate/severe aortic stenosis (AS) and left ventricular systolic dysfunction (LVSD), and its relationship ... Full text Link to item Cite

Relationship of Annular Sizing Using Multidetector Computed Tomographic Imaging and Clinical Outcomes After Self-Expanding CoreValve Transcatheter Aortic Valve Replacement.

Journal Article Circ Cardiovasc Interv · July 2016 BACKGROUND: Multidetector computed tomography is useful for determining the appropriate transcatheter heart valve (THV) size in patients with severe aortic stenosis who are suboptimal surgical candidates. The relationship between adherence to the recommend ... Full text Link to item Cite

3-Year Outcomes in High-Risk Patients Who Underwent Surgical or Transcatheter Aortic Valve Replacement.

Journal Article J Am Coll Cardiol · June 7, 2016 BACKGROUND: In patients with severe aortic stenosis at increased risk for surgery, self-expanding transcatheter aortic valve replacement (TAVR) is associated with improved 2-year survival compared with surgery. OBJECTIVES: This study sought to determine wh ... Full text Link to item Cite

Implementing a Continuous Quality Improvement Program in a High-Volume Clinical Echocardiography Laboratory: Improving Care for Patients With Aortic Stenosis.

Journal Article Circ Cardiovasc Imaging · March 2016 BACKGROUND: The management of aortic stenosis rests on accurate echocardiographic diagnosis. Hence, it was chosen as a test case to examine the utility of continuous quality improvement (CQI) approaches to increase echocardiographic data accuracy and relia ... Full text Open Access Link to item Cite

Changes in Risk Profile and Outcomes of Patients Undergoing Surgical Aortic Valve Replacement From the Pre- to Post-Transcatheter Aortic Valve Replacement Eras.

Journal Article Ann Thorac Surg · January 2016 BACKGROUND: With initiation of transcatheter aortic valve replacement (TAVR) programs, centers may see changes in surgical aortic valve replacement (SAVR) populations and related outcomes because of more high-risk patients undergoing TAVR rather than SAVR. ... Full text Link to item Cite

2-Year Outcomes After Iliofemoral Self-Expanding Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis Deemed Extreme Risk for Surgery.

Journal Article J Am Coll Cardiol · September 22, 2015 BACKGROUND: We reported favorable 1-year outcomes in patients unsuitable for surgery who underwent self-expanding transcatheter aortic valve replacement (TAVR) compared with an objective performance goal. Longer-term outcomes in these patients are not know ... Full text Link to item Cite

Temporal Trends in Disease Severity and Predicted Surgical Risk at the Time of Referral for Echocardiography in Patients Diagnosed with Aortic Stenosis.

Journal Article Crit Pathw Cardiol · September 2015 BACKGROUND: Calcific aortic stenosis (AS) is the most common underlying pathology in patients undergoing heart valve surgery, with an expected increasing prevalence among the aging population. METHODS AND RESULTS: We identified the temporal trends in refer ... Full text Link to item Cite

2-Year Outcomes in Patients Undergoing Surgical or Self-Expanding Transcatheter Aortic Valve Replacement.

Journal Article J Am Coll Cardiol · July 14, 2015 BACKGROUND: The U.S. pivotal trial for the self-expanding valve found that among patients with severe aortic stenosis at increased risk for surgery, the 1-year survival rate was 4.9 percentage points higher in patients treated with a self-expanding transca ... Full text Link to item Cite

Factor VIIa for Annulus Rupture After Transcatheter Aortic Valve Replacement.

Journal Article Ann Thorac Surg · July 2015 Over the last decade, transcatheter aortic valve replacement (TAVR) has emerged as an effective treatment for inoperable and selected high surgical-risk patients with aortic stenosis. However, management of procedural complications with TAVR represents a m ... Full text Link to item Cite

Comparison of aortic annulus size by transesophageal echocardiography and computed tomography angiography with direct surgical measurement.

Journal Article Am J Cardiol · June 1, 2015 This study sought to compare the accuracy of 2-dimensional transesophageal echocardiography (TEE) and computed tomography angiography (CTA) for noninvasive aortic annular sizing as required for transcatheter aortic valve implantation (TAVI). Direct intraop ... Full text Link to item Cite

Incidence of strict versus nonstrict left bundle branch block after transcatheter aortic valve replacement.

Journal Article Am Heart J · March 2015 BACKGROUND: Up to one-third of patients diagnosed with left bundle branch block (LBBB) by conventional electrocardiographic (ECG) criteria are misdiagnosed. Strict LBBB shows decreased left ventricular pumping efficiency compared with nonstrict LBBB. Howev ... Full text Link to item Cite

Predictors and progression of aortic stenosis in patients with preserved left ventricular ejection fraction.

Journal Article Am J Cardiol · January 1, 2015 We aimed to characterize the hemodynamic progression of aortic stenosis (AS) in a contemporary unselected cohort of patients with preserved left ventricular ejection fraction. Current guidelines recommend echocardiographic surveillance of hemodynamic progr ... Full text Link to item Cite

Assessment of single-bolus contrast administration technique using hybrid dual-source ECG-gated thoracic and dual-source non-ECG-gated high-pitch abdominopelvic CT acquisitions for procedural planning before transcatheter aortic valve replacement.

Journal Article J Comput Assist Tomogr · 2015 PURPOSE: This study aimed to assess vascular contrast opacification and homogeneity using single-bolus contrast administration with hybrid thoracic and abdominopelvic computed tomographic angiography in patients with severe aortic valve stenosis. MATERIALS ... Full text Link to item Cite

Immediate mechanical effects of acute left bundle branch block by speckle tracked strain.

Journal Article J Electrocardiol · 2015 INTRODUCTION: Left bundle branch block (LBBB) is a known complication of transcatheter aortic valve replacement (TAVR) and has been shown to predict worsened outcomes in TAVR patients. A regional longitudinal strain pattern, termed the "classic" pattern of ... Full text Link to item Cite

Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery.

Journal Article J Thorac Cardiovasc Surg · December 2014 OBJECTIVES: The CoreValve Extreme Risk US Pivotal Trial enrolled patients with symptomatic severe aortic stenosis deemed unsuitable for surgical aortic valve replacement. Implants were attempted using transfemoral access (n = 489) or an alternative access ... Full text Link to item Cite

Role of cardiac evaluation before thoracic endovascular aortic repair.

Conference J Vasc Surg · November 2014 BACKGROUND: Patients with thoracic aortic disease undergoing thoracic endovascular aortic repair (TEVAR) often have concomitant coronary artery disease and are at risk for perioperative adverse cardiac events. Despite this risk, the need for and extent of ... Full text Link to item Cite

Analysis of geographic variations in the diagnosis and treatment of patients with aortic stenosis in North Carolina.

Journal Article Am J Cardiol · June 1, 2014 Despite advances in the treatment of aortic stenosis (AS), many patients with AS remain untreated. Barriers to accessing cardiovascular surgical care may play a role in this undertreatment. We sought to examine whether there are geographic variations in th ... Full text Link to item Cite

Transcatheter aortic valve replacement using a self-expanding bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery.

Journal Article J Am Coll Cardiol · May 20, 2014 OBJECTIVES: This study sought to evaluate the safety and efficacy of the CoreValve transcatheter heart valve (THV) for the treatment of severe aortic stenosis in patients at extreme risk for surgery. BACKGROUND: Untreated severe aortic stenosis is a progre ... Full text Link to item Cite

Transcatheter aortic-valve replacement with a self-expanding prosthesis.

Journal Article N Engl J Med · May 8, 2014 BACKGROUND: We compared transcatheter aortic-valve replacement (TAVR), using a self-expanding transcatheter aortic-valve bioprosthesis, with surgical aortic-valve replacement in patients with severe aortic stenosis and an increased risk of death during sur ... Full text Link to item Cite

Current status of percutaneous PFO closure.

Journal Article Curr Cardiol Rep · May 2014 The clinical significance of persistent patent foramen ovale (PFO) is not well defined. Empirically, PFO has been associated with many clinical conditions. In cryptogenic stroke, migraine, and orthodeoxia/platypnea, a plausible biologic mechanism exists to ... Full text Link to item Cite

Aortic subannular left ventricular aneurysm: a rare and surgically correctable cause of angina.

Journal Article Ann Thorac Surg · January 2014 Aortic subannular left ventricular aneurysm is a rare form of cardiac pathology. We report a case, including noninvasive and intraoperative imaging, of this entity in a young woman presenting with angina. The patient underwent successful surgical repair an ... Full text Link to item Cite

Impact of ostium secundum atrial septal defect closure on the resolution of falsely positive electrocardiographic criteria for myocardial scarring.

Journal Article J Electrocardiol · 2014 BACKGROUND: Electrocardiographic (ECG) Selvester QRS score criteria with false indication of anteroseptal scarring consistent with myocardial infarction have been found in patients with ostium secundum atrial septal defect (OS-ASD). The objective of this s ... Full text Link to item Cite

Erratum: (Journal of Cardiothoracic and Vascular Anesthesia (2014) 28: 1 (194-95) DOI: 10.1053/j.jvca.2013.11.016)

Journal Article Journal of Cardiothoracic and Vascular Anesthesia · January 1, 2014 Full text Cite

Radiation-associated valvular heart disease.

Journal Article J Heart Valve Dis · November 2013 Therapeutic ionizing radiation, such as that used in the treatment of Hodgkin's lymphoma, can cause cardiac valvular damage that may take several years to manifest as radiation-associated valvular heart disease. Treatment can be complicated by comorbid rad ... Link to item Cite

Surgical correction of aortic valve insufficiency after left ventricular assist device implantation.

Journal Article J Thorac Cardiovasc Surg · November 2013 OBJECTIVES: New-onset aortic insufficiency (AI) can be encountered after instituting mechanical circulatory support and seems more common and severe with continuous flow (CF) left ventricular assist devices (LVADs) compared with pulsatile devices. Treatmen ... Full text Link to item Cite

Invasive hemodynamic evaluation in patients with mechanical aortic valves.

Journal Article Catheter Cardiovasc Interv · July 1, 2013 Invasive hemodynamic evaluation in the patient with a mechanical aortic valve has in the past required transseptal or apical left ventricular puncture in order to obtain left ventricular pressure measurements. Over the last few years, several case reports ... Full text Link to item Cite

Transcatheter aortic valve replacement: an update.

Journal Article Curr Cardiol Rep · June 2013 Aortic stenosis affects many people worldwide with a significant impact on morbidity and mortality with uncorrected, symptomatic aortic valve stenosis carrying mortality of 50% at one year. Degenerative calcific pathology, the most common cause of aortic s ... Full text Link to item Cite

Relationships between cardiac magnetic resonance imaging abnormalities in the inter-ventricular septum and Selvester QRS scoring criteria for anterior-septal myocardial infarction in patients with right ventricular volume overload.

Journal Article J Electrocardiol · 2013 BACKGROUND: Patients with ostium secundum atrial septal defects (ASDs) were studied to determine the prevalence of Selvester anteroseptal myocardial infarction QRS points, and to test the hypothesis that there is a relationship between these criteria and t ... Full text Link to item Cite

Cardiac conduction system disease after transcatheter aortic valve replacement.

Journal Article Am Heart J · November 2012 Transcatheter aortic valve replacement (TAVR) is a rapidly-evolving technology for patients with severe, calcific aortic stenosis. Although these procedures lessen many of the risks and complications of open surgical aortic valve replacement, there remain ... Full text Link to item Cite

Adult Congenital Heart Disease

Journal Article · October 3, 2012 Full text Cite

Echocardiography for the detection of cardiac sources of embolism in patients with stroke or transient ischemic attack.

Journal Article J Stroke Cerebrovasc Dis · October 2012 BACKGROUND: Transthoracic echocardiography (TTE) is commonly obtained during the evaluation of patients with ischemic stroke or transient ischemic attack (TIA) to detect potential sources of cardiogenic embolism. Specific indications for the tests remain u ... Full text Link to item Cite

"What the eyes don't see, the heart doesn't grieve over": epidemiology and risk factors for bloodstream infections following cardiac catheterization.

Journal Article Infect Control Hosp Epidemiol · August 2012 No standard definition exists for surveillance and characterization of the epidemiology of bloodstream infections (BSIs) after cardiac catheterization (CC) procedures. We proposed a novel case definition and determined the epidemiology and risk factors of ... Full text Link to item Cite

Ascending-descending aortic bypass with valve-sparing root replacement for coarctation with aortic root aneurysm.

Journal Article J Thorac Cardiovasc Surg · February 2012 A 55-year-old man with critical aortic coarctation, aortic root aneurysm, and aortic insufficiency underwent median sternotomy for ascending–descending aortic bypass and aortic root replacement. The patient was found to have a salvageable trileaflet aortic ... Full text Link to item Cite

Coronary arteriovenous fistulae: the complexity of coronary artery-to-coronary sinus connections.

Journal Article Tex Heart Inst J · 2012 Coronary artery fistulae are a rare cardiovascular anomaly. Even less common are multiple fistulae involving more than 1 coronary artery. Herein we report the case of a 47-year-old woman who had fistulae from both the right coronary and left circumflex cor ... Link to item Cite

Trends in the use of diagnostic coronary angiography, percutaneous coronary intervention, and coronary artery bypass graft surgery across North Carolina.

Journal Article Am Heart J · November 2011 BACKGROUND: Although variation in use of invasive coronary procedures has been shown, the relationship between invasive diagnostic cardiac catheterization (Cath) and subsequent revascularization with percutaneous coronary intervention (PCI) or coronary art ... Full text Link to item Cite

Association of anemia and long-term survival in patients with pulmonary hypertension.

Journal Article Int J Cardiol · August 4, 2011 BACKGROUND: Anemia is a marker of worsened clinical outcome in patients with heart failure from left ventricular dysfunction. Pulmonary hypertension often results in right ventricular dysfunction. Accordingly we sought to examine the association of hemoglo ... Full text Open Access Link to item Cite

Individualized thoracic aortic replacement for the aortopathy of biscuspid aortic valve disease.

Journal Article J Heart Valve Dis · July 2011 BACKGROUND AND AIM OF THE STUDY: Bicuspid aortic valve (BAV) disease is associated with an aortopathy resulting in aneurysmal dilatation spanning the root, ascending, and arch segments. To date, no large series of proximal aortic replacement in this popula ... Link to item Cite

Response to inhaled nitric oxide predicts survival in patients with pulmonary hypertension.

Journal Article J Card Fail · April 2011 OBJECTIVE: To examine the ability of vasodilator response to predict survival in a diverse cohort of patients with pulmonary hypertension (PH). PATIENTS & METHODS: A total of 214 consecutive treatment-naive patients referred for invasive PH evaluation were ... Full text Open Access Link to item Cite

Anomalous right coronary artery origin from the pulmonary artery (ARCAPA) coexisting with obstructive atherosclerotic disease of the left coronary artery.

Journal Article J Invasive Cardiol · January 2011 Coronary artery anomalies arising from the pulmonary artery are rare, result in reversed flow in the affected coronary artery, and are commonly associated with myocardial ischemia in infancy or childhood. Uncorrected survival to adult age is rare. We prese ... Link to item Cite

Pulmonary hypertension and elevated transpulmonary gradient in patients with mitral stenosis.

Journal Article J Heart Valve Dis · November 2010 BACKGROUND AND AIM OF THE STUDY: Pulmonary hypertension frequently complicates mitral stenosis, with a subset of these patients exhibiting pressures well in excess of their mitral valve hemodynamics. The prevalence of this condition and its impact on clini ... Open Access Link to item Cite

Intraoperative device closure of postinfarction ventricular septal defects.

Journal Article Ann Thorac Surg · June 2010 Postinfarction ventricular septal defects (VSDs) are associated with high mortality and typically these are treated urgently with surgery for exclusion patch repair. Percutaneous closure of postinfarction VSDs using occlusion devices is feasible in some pa ... Full text Link to item Cite

The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum-type atrial septal defect in adults.

Journal Article J Electrocardiol · 2010 BACKGROUND: This study was performed to test the hypothesis that there exists a correlation between the Butler-Leggett (BL) criterion for right ventricular hypertrophy on the electrocardiogram and the Qp/Qs shunt ratio in adults with ostium secundum atrial ... Full text Link to item Cite

Cardiac assessment in acute stroke

Journal Article Emergency Medicine · July 17, 2009 Cite

Pure annular dilation as a cause of mitral regurgitation: a clinically distinct entity of female heart disease.

Journal Article J Heart Valve Dis · May 2009 BACKGROUND AND AIM OF THE STUDY: Pure annular dilation (PAD) is a recognized etiology of mitral regurgitation, yet few data exist to define the prognostic profile of this disorder relative to other etiologies, such as ischemia or myxomatous prolapse. METHO ... Link to item Cite

Pannus-related prosthetic valve dysfunction and life-threatening aortic regurgitation.

Journal Article J Heart Valve Dis · November 2008 Prosthetic valve dysfunction is a rare but life-threatening condition. A 66-year-old woman presented with shock 15 years after aortic valve replacement with a tilting-disc valve. Imaging demonstrated severe aortic insufficiency and a fixed-open prosthetic ... Link to item Cite

Direct en face imaging of secundum atrial septal defects by velocity-encoded cardiovascular magnetic resonance in patients evaluated for possible transcatheter closure.

Journal Article Circ Cardiovasc Imaging · July 2008 BACKGROUND: Atrial septal defect (ASD) flow can be measured indirectly by velocity-encoded cardiovascular magnetic resonance (veCMR) of the pulmonary artery and aorta. Imaging the secundum ASD en face could potentially enable direct flow measurement and pr ... Full text Link to item Cite

Mobile cardiac catheterization laboratories increase use of cardiac care in women and African Americans.

Journal Article Am Heart J · September 2007 BACKGROUND: Women and minorities traditionally have shown less use of diagnostic cardiac catheterization. We sought to determine whether mobile cardiac catheterization laboratories may increase the use of catheterization among women and minorities by bring ... Full text Link to item Cite

Endovascular thoracic aortic aneurysm repair with concomitant myocardial and carotid revascularization.

Journal Article Ann Thorac Surg · July 2007 A 73-year-old woman presented with a large saccular aneurysm involving the distal aortic arch. Preoperative aortography and cardiac catheterization revealed left main coronary artery and left common carotid artery stenoses. Concomitant coronary artery bypa ... Full text Link to item Cite

Peripheral blood levels of matrix metalloproteinases in patients referred for percutaneous balloon mitral valve commissurotomy.

Journal Article J Heart Valve Dis · May 2006 BACKGROUND AND AIM OF THE STUDY: Inflammation may play a central role in the progression of stenotic valvular heart disease. Serum levels of matrix metalloproteinases (MMPs), markers of extracellular matrix (ECM) turnover and potential markers of active in ... Link to item Cite

Where's the flap?

Journal Article J Cardiovasc Magn Reson · 2006 We present a case of aortic intramural hematoma (IMH) in an elderly woman who presented with sudden onset of mid-scapular pain. The patient underwent a series of multimodality imaging studies before the diagnosis of IMH was evident by cardiovascular magnet ... Full text Link to item Cite

Clinical problem-solving. A hole in the argument.

Journal Article N Engl J Med · December 1, 2005 Full text Link to item Cite

The response to inhaled nitric oxide in patients with pulmonary artery hypertension is not masked by baseline vasodilator use.

Journal Article Am Heart J · October 2005 BACKGROUND: Assessment of pulmonary vasodilator responsiveness is important in determining the prognosis and management of patients with pulmonary hypertension. Many patients, however, are already on vasodilators at the time of testing. It is unclear if th ... Full text Link to item Cite

Should we cross the valve: the risk of retrograde catheterization of the left ventricle in patients with aortic stenosis.

Journal Article Am Heart J · July 2004 CLINICAL SCENARIO: A 67-year-old man is referred to your cardiology clinic complaining of worsening angina and dyspnea on exertion. Physical examination reveals a harsh grade IV/VI late-peaking crescendo-decresendo systolic murmur, loudest at the upper ste ... Full text Link to item Cite

Usefulness of percutaneous balloon mitral commissurotomy in preventing the development of atrial fibrillation in patients with mitral stenosis.

Journal Article Am J Cardiol · April 1, 2004 A prospective cohort of patients with mitral stenosis and no history of atrial arrhythmias showed no decrease in the incidence of atrial fibrillation (AF) after successful versus unsuccessful Inoue balloon percutaneous balloon mitral valve commissurotomy. ... Full text Link to item Cite

Incidence and predictors of major vascular complications after percutaneous coronary intervention in the glycoprotein IIb/IIIa platelet inhibitor era.

Journal Article J Interv Cardiol · April 2004 Since the introduction of platelet glycoprotein (GP) IIb/IIIa inhibitors, reports of vascular complications after percutaneous coronary intervention (PCI) have focused on bleeding and the need for surgical repair, whereas specific major vascular complicati ... Full text Link to item Cite

Five-year clinical and echocardiographic evaluation of the Das AngelWings atrial septal occluder.

Journal Article Am Heart J · February 2004 BACKGROUND: The late outcome of patients treated with atrial septal occluder devices remains incompletely defined. The purpose of this study was to assess the late outcome (range 4-7 years postprocedure) of patients in whom the Das AngelWings septal occlud ... Full text Link to item Cite

C-reactive protein elevation independently influences the procedural success of percutaneous balloon mitral valve commissurotomy.

Journal Article Am Heart J · December 2003 BACKGROUND: Markers of systemic inflammation including C-reactive protein (CRP) appear to predict morbidity and mortality in various clinical conditions. The presence of systemic inflammation and its impact on the procedural success of percutaneous balloon ... Full text Link to item Cite

Trained and supervised physician assistants can safely perform diagnostic cardiac catheterization with coronary angiography.

Journal Article Catheter Cardiovasc Interv · June 2003 Using a prospectively collected database of patients undergoing cardiac catheterization, we sought to compare the outcomes of procedures performed by supervised physician assistants (PAs) with those performed by supervised cardiology fellows-in-training. O ... Full text Link to item Cite

An anomalous left coronary artery originating from the pulmonary artery in a 72-year-old woman: diagnosis by color flow myocardial blush and coronary arteriography.

Journal Article J Invasive Cardiol · February 2002 An anomalous left coronary artery originating from the pulmonary artery (ALCAPA) is a rare congenital coronary abnormality often associated with myocardial infarction, congestive heart failure and sudden death. Survival to adulthood in individuals with thi ... Link to item Cite

Serial echocardiographic evaluation of restenosis after successful percutaneous mitral commissurotomy.

Journal Article J Am Coll Cardiol · January 16, 2002 OBJECTIVES: This study was designed to determine predictors of restenosis after successful percutaneous mitral commissurotomy (PMC) and its relationship to late clinical outcome. BACKGROUND: The restenosis rate after PMC and its relationship to late clinic ... Full text Link to item Cite

Cost implications of closure of atrial septal defect.

Journal Article Catheter Cardiovasc Interv · January 2002 We sought to evaluate the relative cost of surgical and device closure of atrial septal defect. Device closure for atrial septal defects is becoming an alternative to surgical closure. We examined the hospital-generated cost data in 13 patients who underwe ... Full text Link to item Cite

Successful percutaneous coronary intervention with stent implantation in anomalous right coronary arteries arising from the left sinus of valsalva: a report of two cases.

Journal Article Catheter Cardiovasc Interv · January 2002 Percutaneous coronary intervention (PCI) in an anomalous right coronary artery arising from the left sinus of valsalva can be technically challenging because of difficulty in selectively cannulating the vessel. We present two cases of successful stent impl ... Full text Link to item Cite

Image quality and coronary blood flow assessment: The influence of radiographic contrast

Journal Article Journal of Clinical and Basic Cardiology · December 1, 2001 The growth of percutaneous coronary intervention has been fostered by technological progress in many areas, including vast improvements in angiographic image quality. Achieving optimal outcomes in coronary intervention requires real-time review of detailed ... Cite

Comparison of results of percutaneous balloon mitral commissurotomy in patients aged > or = 65 years with those in patients aged < 65 years.

Journal Article Am J Cardiol · November 1, 2001 Percutaneous balloon mitral commissurotomy (PBMC) is now first-line therapy in patients with symptomatic mitral stenosis (MS) and favorable valve morphology. Unfortunately, the outcome of Medicare-aged patients undergoing this procedure has not previously ... Full text Link to item Cite

Congenital unilateral pulmonary vein atresia: radiologic findings in three adult patients.

Journal Article AJR Am J Roentgenol · September 2001 OBJECTIVE: The purpose of our study is to describe the radiologic findings of adult patients presenting with congenital unilateral pulmonary vein atresia. CONCLUSION: Chest radiography in affected patients typically reveals a small hemithorax and ipsilater ... Full text Link to item Cite

Correlation between quantitative left atrial spontaneous echocardiographic contrast and intact fibrinogen levels in mitral stenosis.

Journal Article J Am Soc Echocardiogr · April 2001 An association between left atrial spontaneous echocardiographic contrast (LASEC) and thromboembolic events has been recognized. However, the appearance of LASEC and the assessment of its intensity are gain dependent. To evaluate the relation between LASEC ... Full text Link to item Cite

Aortic dissection after angioplasty and stenting of an aortic coarctation: detection by intravascular ultrasonography but not transesophageal echocardiography.

Journal Article J Am Soc Echocardiogr · January 2001 In this case report, an iatrogenic dissection of the descending aorta occurred during balloon angioplasty and stenting of a recurrent coarctation. The dissection was not seen by transesophageal echocardiography, but intravascular ultrasonography, performed ... Full text Link to item Cite

Inhaled nitric oxide selectively dilates pulmonary vasculature in adult patients with pulmonary hypertension, irrespective of etiology.

Journal Article J Am Coll Cardiol · December 2000 OBJECTIVES: We sought to compare the responses of patients with pulmonary hypertension from primary and secondary causes (PPH and SPH, respectively) to inhaled nitric oxide (iNO) in the cardiac catheterization laboratory. BACKGROUND: Pulmonary hypertension ... Full text Link to item Cite

Congenital agenesis of the right pulmonary artery.

Journal Article Catheter Cardiovasc Interv · December 2000 A 44-year-old woman with recurrent pulmonary infections developed severe hemoptysis. Chest radiography revealed a hypoplastic right lung. Absence of the right pulmonary artery, a very rare congenital anomaly, was demonstrated by computed tomography and car ... Full text Link to item Cite

Randomized trial of contrast media utilization in high-risk PTCA: the COURT trial.

Journal Article Circulation · May 9, 2000 BACKGROUND: Previous in vitro and in vivo studies have suggested an association between thrombus-related events and type of contrast media. Low osmolar contrast agents appear to improve the safety of diagnostic and coronary artery interventional procedures ... Full text Link to item Cite

Percutaneous stenting of right pulmonary artery stenosis in fibrosing mediastinitis.

Journal Article Catheter Cardiovasc Interv · March 2000 Pulmonary artery stenosis is an uncommon complication of fibrosing mediastinitis. Previous medical and surgical therapies have provided limited clinical efficacy without objective evidence of clinical improvement. With the advantages of limited invasivenes ... Full text Link to item Cite

Effect of variability in the interpretation of coronary angiograms on the appropriateness of use of coronary revascularization procedures.

Journal Article Am Heart J · January 2000 BACKGROUND: Evidence from numerous studies of coronary angiography show differences between observers' assessments of 15% to 45%. The implication of this variation is serious: If readings are erroneous, some patients will undergo revascularization procedur ... Full text Link to item Cite

Editorial comment: What evidence?

Journal Article ACC Current Journal Review · January 1, 2000 Full text Cite

Assessing the severity of mitral stenosis: variability between noninvasive and invasive measurements in patients with symptomatic mitral valve stenosis.

Journal Article Am Heart J · October 1999 BACKGROUND: This study evaluated the correlation and variability between noninvasive and invasive measures of mitral stenosis severity before and after balloon mitral commissurotomy (BMC) in a large group of patients with symptomatic mitral stenosis. Facto ... Full text Link to item Cite

Mortality and need for reoperation in patients with mild-to-moderate asymptomatic aortic valve disease undergoing coronary artery bypass graft alone.

Journal Article Am Heart J · October 1999 BACKGROUND: Patients presenting for coronary artery bypass graft (CABG) surgery may have concurrent asymptomatic aortic stenosis (AS) or aortic insufficiency (AI). This retrospective study was performed to evaluate outcomes in patients with aortic valve di ... Full text Link to item Cite

Hypoxemia after prior cardiac surgery due to interatrial shunting and its treatment with a novel transcatheter occlusion device.

Journal Article Catheter Cardiovasc Interv · April 1999 We describe two unusual cases of hypoxemia after cardiac surgery due to intracardiac right-to-left shunting through a patent foramen ovale or atrial septal defect. The interatrial defects were successfully occluded by placement of a novel, transcather devi ... Full text Link to item Cite

Predictors and significance of atrial rhythm before and six months after percutaneous balloon mitral commissurotomy.

Journal Article Am J Cardiol · January 1, 1999 Clinical, echocardiographic, and cardiac catheterization data were evaluated in 263 patients with mitral stenosis who were undergoing balloon commissurotomy to determine the predictors of atrial rhythm and its effect on functional status. Conversion from a ... Full text Link to item Cite

What does the left atrial v wave signify during balloon commissurotomy of mitral stenosis?

Journal Article Am J Cardiol · December 1, 1998 Left atrial v-wave amplitude has been associated with the presence and severity of chronic mitral regurgitation (MR) but it has not been evaluated for the detection of acute MR. We evaluated the left atrial v-wave amplitude of 205 consecutive patients with ... Full text Link to item Cite

Determinants of 15-year outcome with 1,119 standard Carpentier-Edwards porcine valves.

Journal Article Ann Thorac Surg · December 1998 BACKGROUND: The determinants of long-term outcome 15 years or more after porcine valve replacement are poorly documented. METHODS: A retrospective review was performed of patients undergoing valve replacement with standard Carpentier-Edwards aortic (n = 53 ... Full text Link to item Cite

Comparison of open mitral commissurotomy with mitral valve replacement with or without chordal preservation in patients with mitral stenosis

Journal Article Circulation · November 10, 1998 Background - Percutaneous balloon mitral valvuloplasty and durable mitral prostheses have made the role of open mitral commissurotomy (OMC) uncertain. Methods and Results - Results from the use of St Jude mitral valve replacement (SJMVR) were compared with ... Cite

Doppler pressure half-time method of assessing mitral valve area: aortic insufficiency does not adversely affect validity.

Journal Article Am Heart J · October 1998 OBJECTIVES: This study evaluated the effect of aortic insufficiency on the correlation of pressure half-time-derived mitral valve area with each of 2 standards for mitral valve area (planimetry and cardiac catheterization) in a prospectively assembled coho ... Full text Link to item Cite

Partially anomalous pulmonary venous connection: demonstration of dual drainage allowing nonsurgical correction.

Journal Article Cathet Cardiovasc Diagn · July 1998 We describe a novel percutaneous approach for correction of partially anomalous pulmonary venous connection. We describe two cases of dual pulmonary venous drainage where embolization of the anomalous pulmonary venous connection was successful. ... Full text Link to item Cite

The Ross procedure: shorter hospital stay, decreased morbidity, and cost effective.

Journal Article Ann Thorac Surg · June 1998 BACKGROUND: The Ross procedure has become an accepted and sometimes preferred alternative to mechanical aortic valve replacement. One criticism of the Ross procedure is that it may have a higher operative mortality, morbidity, and cost. Several groups have ... Full text Link to item Cite

Percutaneous stenting of superior vena cava syndrome: a case report and review of the literature.

Journal Article Am J Med · January 1998 Superior vena cava syndrome (SVCS) is a distressing manifestation of benign or malignant disease obstructing return of blood flow through the superior vena cava (SVC). Treatment, often centering around management of the underlying illness, may be slow in r ... Full text Link to item Cite

Simultaneous biplane coronary and pulmonary arteriography: a novel technique for defining the course of an anomalous left main coronary artery originating from the right sinus of Valsalva.

Journal Article Cathet Cardiovasc Diagn · September 1997 We present a novel technique employing biplane cineangiography with simultaneous left coronary and pulmonary angiography to define the anomalous course of the left main coronary artery when it originates from the right sinus of Valsalva. These biplane cine ... Full text Link to item Cite

Lossy (15:1) JPEG compression of digital coronary angiograms does not limit detection of subtle morphological features.

Journal Article Circulation · August 19, 1997 BACKGROUND: Development of the "all-digital" cardiac catheterization laboratory has been slowed by substantial computer archival and transfer requirements. Lossy data compression reduces this burden but creates irreversible changes in images, potentially i ... Full text Link to item Cite

Role of right ventricular and pulmonary functional abnormalities in limiting exercise capacity in adults with congenital heart disease.

Journal Article Am J Cardiol · August 1, 1997 This study evaluates right ventricular (RV) and pulmonary function during exercise in adults with congenital heart disease (CHD). Thirty-one patients with CHD involving the right side of the heart underwent symptom-limited bicycle exercise testing with sim ... Full text Link to item Cite

Effect of inadequate cardiac output reserve on exercise tolerance in patients with moderate mitral stenosis.

Journal Article Am J Cardiol · July 15, 1997 Twenty-nine patients with moderate mitral stenosis and 29 age-matched normal controls underwent symptom-limited upright bicycle exercise testing with simultaneous hemodynamic monitoring. Exercise tolerance in the mitral stenosis group was found to be limit ... Full text Link to item Cite

Balloon aortic valvuloplasty.

Journal Article Prog Cardiovasc Dis · 1997 Balloon aortic valvuloplasty is a percutaneous, therapeutic option for patients with severe aortic stenosis, yet the effectiveness of this procedure is dependent on the morphology of the stenotic aortic valve and the respective mechanism of dilation. In yo ... Full text Link to item Cite

Managing clinically insignificant aortic valve disease in patients undergoing CABG

Journal Article ACC Current Journal Review · January 1, 1997 The studies that have addressed combined CABG and AVR in those with significant coronary artery disease and asymptomatic aortic valve disease offer important insight into the management of this subset of patients. From the information available, we can con ... Full text Cite

Balloon aortic valvuloplasty: Failure to improve long-term survival for the elderly

Journal Article Cardiology Review · December 1, 1996 In this study of 165 elderly patients with severe symptomatic aortic valve stenosis treated with balloon valvuloplasty, long-term event-free and actuarial survival was poor regardless of symptoms at presentation and resembled the natural history of untreat ... Cite

Esophageal varices in association with unilateral pulmonary vein atresia.

Journal Article Cathet Cardiovasc Diagn · August 1996 A 27-yr-old woman with recurrent episodes of hemoptysis (and hematemesis due to esophageal varices) was found to have unilateral pulmonary vein atresia. Reversed flow in the left pulmonary artery, a finding highly suggestive of this rare congenital anomaly ... Full text Link to item Cite

Late conduit occlusion after modified Fontan procedure with classic Glenn shunt.

Journal Article Ann Thorac Surg · July 1996 A number of patients with complex congenital heart disease who were initially palliated with a classic Glenn shunt subsequently underwent modified Fontan procedures. This report discusses the operative management of complete occlusion of right atrial-to-ri ... Full text Link to item Cite

Total pulmonary artery occlusion immediately after lung transplantation: successful revascularization with intravascular stents.

Journal Article J Heart Lung Transplant · May 1996 Occlusion of the pulmonary artery anastomosis is an uncommon early complication of lung transplantation which necessitates emergency surgical revision. Percutaneous correction of such a complication has not been previously reported. We report a patient who ... Link to item Cite

Delayed right heart failure following lung transplantation.

Journal Article Chest · February 1996 Dynamic right ventricular outflow tract obstruction (RVOTO) has been reported following lung transplantation for pulmonary hypertension, usually in association with the use of inotropic agents. This report describes delayed severe right-sided heart failure ... Full text Link to item Cite

Balloon aortic valvuloplasty in adults: failure of procedure to improve long-term survival.

Journal Article J Am Coll Cardiol · November 15, 1995 OBJECTIVES: This study sought to determine the long-term outcome of adult patients undergoing percutaneous balloon aortic valvuloplasty. BACKGROUND: Percutaneous balloon aortic valvuloplasty has been offered as an alternative to aortic valve replacement fo ... Full text Link to item Cite

Left ventricular performance improves late after aortic valve replacement in patients with aortic stenosis and reduced ejection fraction.

Journal Article Am J Cardiol · September 15, 1995 EF in patients with aortic stenosis and reduced EF who underwent aortic valve replacement did not improve by 1 week postoperatively despite rectification of afterload mismatch. By 6 months, however, EF significantly improved without any further change in v ... Full text Link to item Cite

Carcinoid heart disease. Correlation of high serotonin levels with valvular abnormalities detected by cardiac catheterization and echocardiography.

Journal Article Circulation · August 15, 1995 BACKGROUND: Although serotonin has been postulated as an etiologic agent in the development of carcinoid heart disease, no direct evidence for different ambient serotonin levels in cardiac and noncardiac patients has been reported to date. METHODS AND RESU ... Full text Link to item Cite

The forgotten chamber: the importance of the right ventricle.

Journal Article Cathet Cardiovasc Diagn · May 1995 Historically, the right heart was viewed as less important than the left heart in the maintenance of normal overall hemodynamic performance. However, there is now considerable evidence that emphasizes the significance of intact right ventricular (RV) funct ... Full text Link to item Cite

Predictors of outcome of tricuspid valve replacement in carcinoid heart disease.

Journal Article Am J Cardiol · March 1, 1995 The cardiac valvular surgical experience of patients in the Duke Carcinoid Database was reviewed to assess operative outcome. Of the 604 patients in the database, 19 patients with carcinoid heart disease were identified by cardiac catheterization or echoca ... Full text Link to item Cite

Transesophageal echocardiographic assessment of reversal of systolic pulmonary venous flow in mitral stenosis.

Journal Article Am J Cardiol · January 1, 1995 Transesophageal echocardiography and diagnostic cardiac catheterization were performed in 36 patients with symptomatic mitral stenosis to assess the incidence and significance of systolic flow reversal in the pulmonary veins. Mitral regurgitation was grade ... Full text Link to item Cite

Aortic valve replacement in adults after balloon aortic valvuloplasty

Journal Article Circulation · November 1, 1994 Background: Percutaneous balloon aortic valvuloplasty is limited by a high risk of procedural morbidity, transient clinical benefit, and a high restenosis rate. The management of patients with symptomatic aortic valve restenosis after percutaneous balloon ... Cite

Value of transthoracic echocardiography in predicting embolic events in active infective endocarditis. Duke Endocarditis Service.

Journal Article Am J Cardiol · October 15, 1994 The purpose of this study was twofold: (1) to determine interobserver variability of echocardiographic characteristics of vegetations in patients with infective endocarditis, and (2) to assess the value of these vegetation characteristics in predicting emb ... Full text Link to item Cite

Relief of superior vena cava syndrome due to fibrosing mediastinitis using the Palmaz stent.

Journal Article Chest · July 1994 Relief of superior vena cava (SVC) syndrome due to non-neoplastic mediastinal disease presents a formidable challenge. Long-term patency of surgically created bypass grafts has been poor, and the morbidity associated with these procedures is substantial. W ... Full text Link to item Cite

Adult patients with congenital heart disease.

Journal Article N C Med J · April 1994 Adult patients with congenital heart disease present complex problems that require individualized management. Unfortunately, few physicians who care for adults with congenital heart disease have received adequate specific training to deal with their proble ... Link to item Cite

New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service.

Journal Article Am J Med · March 1994 PURPOSE: This study was designed to develop improved criteria for the diagnosis of infective endocarditis and to compare these criteria with currently accepted criteria in a large series of cases. PATIENTS AND METHODS: A total of 405 consecutive cases of s ... Full text Link to item Cite

Complications related to percutaneous transvenous mitral commissurotomy.

Journal Article Cathet Cardiovasc Diagn · 1994 Recent randomized studies have demonstrated that percutaneous transvenous mitral commissurotomy (PTMC) has similar efficacy compared to surgical commissurotomy. Compared with surgery, PTMC is associated with shorter hospital stays, reduced patient discomfo ... Link to item Cite

Comparison of balloon valvuloplasty with operative treatment for mitral stenosis.

Journal Article Ann Thorac Surg · December 1993 To determine the optimal role for percutaneous balloon mitral valvuloplasty or open mitral commissurotomy, the outcome of 164 consecutive patients undergoing either percutaneous balloon mitral valvuloplasty, open mitral commissurotomy, or mitral valve repl ... Full text Link to item Cite

Systolic left ventricular function after reperfusion therapy for acute myocardial infarction. Analysis of determinants of improvement. The TAMI Study Group.

Journal Article Circulation · May 1993 BACKGROUND: Contrast ventriculograms of 542 patients treated with intravenous thrombolytic agents for acute myocardial infarction were examined to define changes in left ventricular ejection fraction and regional wall motion that occur during the first wee ... Full text Link to item Cite

Stunned myocardium in the toxic shock syndrome.

Journal Article Ann Intern Med · December 1, 1992 Full text Link to item Cite

Ejection load changes in aortic stenosis. Observations made after balloon aortic valvuloplasty.

Journal Article Circ Res · November 1992 To investigate complementarity and competitiveness between the intrinsic and extrinsic components of the total left ventricular systolic load, hemodynamic data from 18 elderly subjects with severe aortic stenosis were analyzed before and after balloon dila ... Full text Link to item Cite

Ergonovine maleate testing during cardiac catheterization: a 10-year perspective in 3,447 patients without significant coronary artery disease or Prinzmetal's variant angina.

Journal Article J Am Coll Cardiol · July 1992 The utility of ergonovine testing for coronary artery spasm was assessed in 3,447 patients with angiographically insignificant (less than 50% diameter stenosis) or no coronary artery disease. No patients clinically had Prinzmetal's variant angina. Overall, ... Full text Link to item Cite

Renal artery stenosis: prevalence and associated risk factors in patients undergoing routine cardiac catheterization.

Journal Article J Am Soc Nephrol · May 1992 The purposes of this study were to determine the prevalence of angiographically significant renal artery stenosis in a patient population referred for diagnostic cardiac catheterization and to develop a model that predicts the highest-risk subset of patien ... Full text Link to item Cite

Use of balloon occlusion to improve visualization of anomalous pulmonary venous return in an adult with cor triatriatum.

Journal Article Cathet Cardiovasc Diagn · April 1992 Cor triatriatum, although rare in adults, is often associated with anomalous pulmonary venous return. Accurate diagnosis of the pulmonary venous return and its anatomic connections is essential in planning proper surgical correction. This case illustrates ... Full text Link to item Cite

Critical mitral stenosis causing ischemic hepatic failure. Successful treatment by percutaneous balloon mitral valvotomy.

Journal Article Chest · March 1992 We report a 52-year-old patient with severe mitral stenosis who developed new onset atrial fibrillation, low output congestive heart failure and fulminant ischemic hepatic failure with subsequent severe coagulopathy. Percutaneous mitral valvotomy resulted ... Full text Link to item Cite

Left ventricular filling and ventricular diastolic performance after percutaneous balloon mitral valvotomy.

Journal Article Am J Cardiol · January 1, 1992 The time course of left ventricular (LV) filling and LV diastolic performance were examined in 27 consecutive patients in sinus rhythm before and acutely after balloon mitral valvotomy (BMV). The mitral valve area acutely increased from 1.1 +/- 0.3 to 2.1 ... Full text Link to item Cite

Predictors of one-year outcome after balloon aortic valvuloplasty

Journal Article Cardiology Board Review · January 1, 1992 Cite

Effectiveness of percutaneous balloon mitral valvotomy during pregnancy.

Journal Article Am J Cardiol · October 1, 1991 During pregnancy, medically refractory congestive heart failure due to mitral stenosis continues to present a clinical challenge and optimal management remains controversial. Thirteen women underwent balloon mitral valvotomy for control of functional class ... Full text Link to item Cite

Surgical aortic valvuloplasty using the Cavitron Ultrasonic Surgical Aspirator: an invasive hemodynamic follow-up study.

Journal Article Cathet Cardiovasc Diagn · September 1991 Valve repair and calcium debridement in patients with calcific aortic stenosis, using the Cavitron Ultrasonic Surgical Aspirator (CUSA), results in a reduction in the aortic valve gradient while potentially avoiding long-term problems inherent to prostheti ... Full text Link to item Cite

Determinants of one-year outcome from balloon aortic valvuloplasty.

Journal Article Am J Cardiol · July 1, 1991 Balloon aortic valvuloplasty (BAV) has been a therapeutic alternative treatment for severe symptomatic aortic stenosis. Previous studies have been unable to predict 1-year outcome because of limited acute and follow-up clinical, invasive and echocardiograp ... Full text Link to item Cite

Comparison of intravascular ultrasound, external ultrasound and digital angiography for evaluation of peripheral artery dimensions and morphology.

Journal Article Am J Cardiol · April 15, 1991 Validation of catheter-based intravascular ultrasound imaging has been based on comparisons with histology and digital angiography, each of which may have limitations in the assessment of arterial size and morphology. External, high-frequency ultrasound ca ... Full text Link to item Cite

Percutaneous balloon pulmonic valvuloplasty following treated endocarditis in a patient with congenital pulmonary valve stenosis.

Journal Article Cathet Cardiovasc Diagn · December 1990 A 36-year-old woman with congenital pulmonary valve stenosis developed the rare complication of endocarditis of the valve. After successful sterilization of the valve, the patient underwent percutaneous balloon pulmonic valvuloplasty at a later date. The p ... Full text Link to item Cite

Serial left ventricular performance evaluated by cardiac catheterization before, immediately after and at 6 months after balloon aortic valvuloplasty.

Journal Article J Am Coll Cardiol · November 1990 Although impaired ventricular function has been shown to improve after aortic valve replacement, there are few data on hemodynamic changes after balloon aortic valvuloplasty based on follow-up catheterization. Of 71 patients surviving 6 months after balloo ... Full text Link to item Cite

A rapid, effective technique for retrograde crossing of valvular aortic stenosis using standard coronary catheters.

Journal Article Cathet Cardiovasc Diagn · September 1990 Retrograde crossing of valvular aortic stenosis can be challenging even to experienced angiographers. In 446 of 447 consecutive patients with aortic stenosis catheterized during the past 3 years, a technique using a standard Judkins right coronary catheter ... Full text Link to item Cite

Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology.

Journal Article J Am Coll Cardiol · September 1990 The accuracy of catheter-based intravascular ultrasonography to define luminal size in humans in vivo and its sensitivity to describe lesion morphology have not been previously reported. Vessel diameter, cross-sectional area and lesion characteristics asse ... Full text Link to item Cite

Balloon angioplasty of coarctation of the aorta evaluated with intravascular ultrasound imaging.

Journal Article J Am Coll Cardiol · March 15, 1990 Intravascular ultrasound images were employed to evaluate aortic coarctation before and after balloon angioplasty. Measurements obtained with use of an ultrasound imaging catheter correlated well with measurements made with digital aortography, both in the ... Full text Link to item Cite

Failure of balloon aortic valvuloplasty to result in sustained clinical improvement in patients with depressed left ventricular function.

Journal Article Am J Cardiol · January 1, 1990 Although balloon aortic valvuloplasty usually results in acute hemodynamic improvement, recurrent symptoms often occur within several months. The current study was designed to determine whether clinical characteristics, including invasive hemodynamic param ... Full text Link to item Cite

Platypnea-orthodeoxia and progressive autonomic failure.

Journal Article Am Rev Respir Dis · December 1989 Platypnea-orthodeoxia has been described in patients with pulmonary shunts, intracardiac shunts, and severe lung disease. We report a case of platypnea-orthodeoxia in a patient with minimal obstructive lung disease and progressive autonomic failure. We hav ... Full text Link to item Cite