Journal ArticleUltrasound Med Biol · August 2023
OBJECTIVE: Increased myocardial stiffness (MS) is an important hallmark of cardiac amyloidosis (CA) caused by myocardial amyloid deposition. Standard echocardiography metrics assess MS indirectly via downstream effects of cardiac stiffening. The ultrasound ...
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Journal ArticleChest · March 2022
Immersion pulmonary edema, more commonly referred to as swimming-induced pulmonary edema (SIPE), is a well-documented condition believed to be a result of immersion physiologic condition that is characterized by a peripheral-to-central redistribution of bl ...
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Journal ArticleInt J Cardiovasc Imaging · June 2021
Cardiac resynchronization therapy (CRT) reduces the risk of ventricular arrhythmias (VA) in heart failure (HF) patients with left bundle branch block (LBBB) while the effect is less clear among non-LBBB patients. This study aimed to investigate if absence ...
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Journal ArticleAm Heart J · January 2021
BACKGROUND: Few therapies improve outcomes in patients with heart failure with preserved ejection fraction (HFpEF). If left bundle-branch block (LBBB) is associated with left ventricular dyssynchrony and impaired cardiac performance in HFpEF, cardiac resyn ...
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Journal ArticleAm J Cardiol · December 15, 2020
Left bundle branch block (LBBB) increases the likelihood of developing reduced left ventricular (LV) ejection fraction (EF) but predicting which patients with LBBB and normal LVEF will develop decreased LVEF remains challenging. Fifty patients with LBBB an ...
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Journal ArticlePacing Clin Electrophysiol · November 2020
BACKGROUND: Biventricular (BiV) pacing increases transmural repolarization heterogeneity due to epicardial to endocardial conduction from the left ventricular (LV) lead. However, limited evidence is available on concomitant changes in ventricular depolariz ...
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Journal ArticlePLoS Negl Trop Dis · November 2020
UNLABELLED: Chagas disease (CD) will account for 200,000 cardiovascular deaths worldwide over the next 5 years. Early detection of chronic Chagas cardiomyopathy (CCC) is a challenge. We aimed to test if speckle-tracking echocardiography (STE) can detect in ...
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Journal ArticleUltrasound Med Biol · September 2020
The real time high frame rate (HFR) 2-dimensional ultrasound system, T5, at Duke University is capable of imaging at up to 1000 images per second for adult cardiac imaging. A method for detecting and visualizing the mechanical contraction fronts using HFR ...
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Journal ArticleAIDS · March 15, 2020
OBJECTIVE: To define the prevalence of early cardiac dysfunction in children and young adults with perinatally acquired HIV and predictors of cardiac function. DESIGN: Cross-sectional design. METHODS: Early cardiac dysfunction was defined as left ventricul ...
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Journal ArticlePacing Clin Electrophysiol · November 2019
BACKGROUND: PR interval prolongation is associated with poor outcome after cardiac resynchronization therapy (CRT) among patients with left bundle branch block (LBBB) but the mechanisms are unknown. We investigated clinical outcomes, electrocardiogram (ECG ...
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Journal ArticleJ Cardiovasc Electrophysiol · November 2019
BACKGROUND: Changes in left ventricular (LV) activation after cardiac resynchronization therapy (CRT) influence survival but are difficult to quantify noninvasively. METHODS AND RESULTS: We studied 527 CRT patients to assess whether noninvasive quantificat ...
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Journal ArticleAm J Cardiol · October 15, 2019
Echocardiography is a key tool in the management of patients with pulmonary arterial hypertension (PAH), but many potential parameters could be used to assess response to therapy. In this retrospective study of 48 patients with severe PAH at baseline, we e ...
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Journal ArticleCardiovasc Ultrasound · October 10, 2019
BACKGROUND: Nearly one-third of heart failure (HF) patients do not respond to cardiac resynchronization therapy (CRT) despite having left bundle branch block (LBBB). The aim of the study was to investigate a novel method of quantifying left ventricular (LV ...
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Journal ArticleCardiovasc Ultrasound · May 21, 2019
BACKGROUND: The association of a Classical left bundle branch block (LBBB) contraction pattern and better outcome after cardiac resynchronization therapy (CRT) has only been studied using vendor-specific software for echocardiographic speckle-tracked longi ...
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Journal ArticleUltrasound Med Biol · May 2019
Recently, we developed a high-frame-rate echocardiographic imaging system capable of acquiring images at rates up to 2500 per second. High imaging rates were used to quantify longitudinal strain parameters in patients with echocardiographically normal func ...
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Journal ArticleUltrasound Med Biol · May 2019
Myocardial stiffness exhibits cyclic variations over the course of the cardiac cycle. These trends are closely tied to the electromechanical and hemodynamic changes in the heart. Characterization of dynamic myocardialstiffness can provide insights into the ...
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Journal ArticleAm J Cardiol · March 1, 2019
The introduction of transcatheter aortic valve implantation (TAVI) has revolutionized the treatment of patients with severe aortic stenosis (AS). However, despite the great clinical success of TAVI, less is known about the cardiac hemodynamics and structur ...
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Journal ArticleHeart Rhythm · February 2019
BACKGROUND: Recent studies have suggested that vectorcardiographic measures predict left ventricular (LV) reverse remodeling and clinical outcome in patients receiving cardiac resynchronization therapy (CRT). OBJECTIVES: The objectives of this study were t ...
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Journal ArticleUltrasound Med Biol · August 2023
OBJECTIVE: Increased myocardial stiffness (MS) is an important hallmark of cardiac amyloidosis (CA) caused by myocardial amyloid deposition. Standard echocardiography metrics assess MS indirectly via downstream effects of cardiac stiffening. The ultrasound ...
Full textLink to itemCite
Journal ArticleChest · March 2022
Immersion pulmonary edema, more commonly referred to as swimming-induced pulmonary edema (SIPE), is a well-documented condition believed to be a result of immersion physiologic condition that is characterized by a peripheral-to-central redistribution of bl ...
Full textLink to itemCite
Journal ArticleInt J Cardiovasc Imaging · June 2021
Cardiac resynchronization therapy (CRT) reduces the risk of ventricular arrhythmias (VA) in heart failure (HF) patients with left bundle branch block (LBBB) while the effect is less clear among non-LBBB patients. This study aimed to investigate if absence ...
Full textLink to itemCite
Journal ArticleAm Heart J · January 2021
BACKGROUND: Few therapies improve outcomes in patients with heart failure with preserved ejection fraction (HFpEF). If left bundle-branch block (LBBB) is associated with left ventricular dyssynchrony and impaired cardiac performance in HFpEF, cardiac resyn ...
Full textLink to itemCite
Journal ArticleAm J Cardiol · December 15, 2020
Left bundle branch block (LBBB) increases the likelihood of developing reduced left ventricular (LV) ejection fraction (EF) but predicting which patients with LBBB and normal LVEF will develop decreased LVEF remains challenging. Fifty patients with LBBB an ...
Full textLink to itemCite
Journal ArticlePacing Clin Electrophysiol · November 2020
BACKGROUND: Biventricular (BiV) pacing increases transmural repolarization heterogeneity due to epicardial to endocardial conduction from the left ventricular (LV) lead. However, limited evidence is available on concomitant changes in ventricular depolariz ...
Full textLink to itemCite
Journal ArticlePLoS Negl Trop Dis · November 2020
UNLABELLED: Chagas disease (CD) will account for 200,000 cardiovascular deaths worldwide over the next 5 years. Early detection of chronic Chagas cardiomyopathy (CCC) is a challenge. We aimed to test if speckle-tracking echocardiography (STE) can detect in ...
Full textLink to itemCite
Journal ArticleUltrasound Med Biol · September 2020
The real time high frame rate (HFR) 2-dimensional ultrasound system, T5, at Duke University is capable of imaging at up to 1000 images per second for adult cardiac imaging. A method for detecting and visualizing the mechanical contraction fronts using HFR ...
Full textLink to itemCite
Journal ArticleAIDS · March 15, 2020
OBJECTIVE: To define the prevalence of early cardiac dysfunction in children and young adults with perinatally acquired HIV and predictors of cardiac function. DESIGN: Cross-sectional design. METHODS: Early cardiac dysfunction was defined as left ventricul ...
Full textLink to itemCite
Journal ArticlePacing Clin Electrophysiol · November 2019
BACKGROUND: PR interval prolongation is associated with poor outcome after cardiac resynchronization therapy (CRT) among patients with left bundle branch block (LBBB) but the mechanisms are unknown. We investigated clinical outcomes, electrocardiogram (ECG ...
Full textLink to itemCite
Journal ArticleJ Cardiovasc Electrophysiol · November 2019
BACKGROUND: Changes in left ventricular (LV) activation after cardiac resynchronization therapy (CRT) influence survival but are difficult to quantify noninvasively. METHODS AND RESULTS: We studied 527 CRT patients to assess whether noninvasive quantificat ...
Full textLink to itemCite
Journal ArticleAm J Cardiol · October 15, 2019
Echocardiography is a key tool in the management of patients with pulmonary arterial hypertension (PAH), but many potential parameters could be used to assess response to therapy. In this retrospective study of 48 patients with severe PAH at baseline, we e ...
Full textLink to itemCite
Journal ArticleCardiovasc Ultrasound · October 10, 2019
BACKGROUND: Nearly one-third of heart failure (HF) patients do not respond to cardiac resynchronization therapy (CRT) despite having left bundle branch block (LBBB). The aim of the study was to investigate a novel method of quantifying left ventricular (LV ...
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Journal ArticleCardiovasc Ultrasound · May 21, 2019
BACKGROUND: The association of a Classical left bundle branch block (LBBB) contraction pattern and better outcome after cardiac resynchronization therapy (CRT) has only been studied using vendor-specific software for echocardiographic speckle-tracked longi ...
Full textLink to itemCite
Journal ArticleUltrasound Med Biol · May 2019
Recently, we developed a high-frame-rate echocardiographic imaging system capable of acquiring images at rates up to 2500 per second. High imaging rates were used to quantify longitudinal strain parameters in patients with echocardiographically normal func ...
Full textLink to itemCite
Journal ArticleUltrasound Med Biol · May 2019
Myocardial stiffness exhibits cyclic variations over the course of the cardiac cycle. These trends are closely tied to the electromechanical and hemodynamic changes in the heart. Characterization of dynamic myocardialstiffness can provide insights into the ...
Full textLink to itemCite
Journal ArticleAm J Cardiol · March 1, 2019
The introduction of transcatheter aortic valve implantation (TAVI) has revolutionized the treatment of patients with severe aortic stenosis (AS). However, despite the great clinical success of TAVI, less is known about the cardiac hemodynamics and structur ...
Full textLink to itemCite
Journal ArticleHeart Rhythm · February 2019
BACKGROUND: Recent studies have suggested that vectorcardiographic measures predict left ventricular (LV) reverse remodeling and clinical outcome in patients receiving cardiac resynchronization therapy (CRT). OBJECTIVES: The objectives of this study were t ...
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Journal ArticleInt J Cardiovasc Imaging · November 2018
Quality in stress echocardiography interpretation is often gauged against coronary angiography (CA) data but anatomic obstructive coronary disease on CA is an imperfect gold standard for a stress induced wall motion abnormality. We examined the utility of ...
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Journal ArticleAm Heart J · September 2018
BACKGROUND: We aimed to determine the association of MR severity and type with all-cause death in a large, real-world, clinical setting. METHODS: We reviewed full echocardiography studies at Duke Echocardiography Laboratory (01/01/1995-12/31/2010), classif ...
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Journal ArticleAm J Cardiol · September 1, 2018
In pulmonary hypertension (PH), measurement of various echocardiographic parameters that assess right heart function is recommended by current clinical guidelines. Limited data exists on the combined value of clinical and echocardiographic parameters in pr ...
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Journal ArticleUltrason Imaging · July 2018
Transmit beamforming has a strong impact on several factors that govern image quality, field-of-view, and frame-rate in ultrasound imaging. For cardiac applications, the visualization of fine structures and the ability to track their motion is equally impo ...
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Journal ArticleJ Am Soc Echocardiogr · June 2018
BACKGROUND: Right ventricular peak systolic longitudinal strain (RVLS) has emerged as an approach for quantifying right ventricular function in diseases such as pulmonary hypertension and congenital heart disease. A major limitation in applying RVLS is tha ...
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Journal ArticleInt J Cardiol · June 1, 2018
BACKGROUND: Impaired cardiac function is the main predictor of poor outcome in infective endocarditis (IE). Global longitudinal strain (GLS) derived from two-dimensional strain echocardiography has proven superior in prediction of long-term outcome as comp ...
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Journal ArticleJ Am Coll Cardiol · January 23, 2018
BACKGROUND: Patients with left bundle branch block (LBBB) often respond to cardiac resynchronization therapy (CRT) with left ventricular ejection fraction (LVEF) improvement. Guideline-directed medical therapy (GDMT), not CRT, is first-line therapy for pat ...
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Journal ArticleEchocardiography · January 2018
BACKGROUND: Use of echocardiography (echo) has exponentially increased in recent decades. Concerned about this scientific society developed appropriate use criteria (AUC). Clinical management still suffers geographical variations, and no objective data are ...
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Journal ArticleJ Electrocardiol · 2018
Cardiac resynchronization therapy (CRT) has revolutionized the care of patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB); some hypothesize that electrical resynchronization may also benefit patients with ...
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Chapter · January 1, 2018
Varying degrees of heart failure is common in infants with complex single ventricular heart disease. Sometimes the heart failure is progressive without a clear etiology and unresponsive to intense pharmacotherapy creating a critical management dilemma. The ...
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Chapter · January 1, 2018
Echocardiography is the most common method for the detection of cardiac masses. Masses can be described as intracavitary (within chambers or great vessels, and attached to chamber walls, valves or great vessels) or intramural (located within the muscular s ...
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Chapter · January 1, 2018
Infective endocarditis (IE) is an infection of the endocardial lining of the heart, the heart valves, intracardiac devices or prosthetic valves. The infection is mainly localized on the valvular structures, generally on the flow side of the valves or at lo ...
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Chapter · January 1, 2018
The mitral valve is the most easily recognized moving structure in the heart. Because of its rapid back and forth motion, the mitral valve serves as “home base” for almost all echocardiographic examinations. When the transducer is directed posteriorly from ...
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Book · January 1, 2018
This updated textbook provides an essential evidence-based approach to echocardiography and includes practical case-based instruction illustrating a wide variety of clinical scenarios in which echocardiography is a vital diagnostic option for physicians. I ...
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Chapter · January 1, 2018
Measurement of myocardial global longitudinal strain (GLS) is no longer a research tool. Rather, GLS is now used for risk assessment and management of patients with a wide variety of clinical disorders. GLS is clearly a useful supplement to routine quantit ...
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Chapter · January 1, 2018
There are two major functional applications for speckle tracked strain used in the study of cardiac function: global and regional. This chapter is about regional functional strain assessment. The basics of ultrasound speckle tracking and strain are discuss ...
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Journal ArticleAm J Cardiol · December 1, 2017
We compared the incidence of left ventricular systolic dysfunction (LVSD) among patients with left bundle branch block (LBBB) to a matched cohort of patients with a narrow QRS duration <120 ms (NQRS). We hypothesized patients with preserved ejection fracti ...
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Journal ArticlePacing Clin Electrophysiol · December 2017
BACKGROUND: Some patients with RBBB may respond to cardiac resynchronization therapy (CRT). However, little is known regarding the electromechanical substrate for CRT and whether this is the optimal pacing strategy. METHODS: This was a pilot prospective do ...
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ConferenceIEEE International Ultrasonics Symposium, IUS · October 31, 2017
Cardiac function has traditionally been studied using pressure-volume (PV) loop analysis. PV loops can be used to derive functional indices such as end-systolic pressure volume relationship (ESPVR) - a measure of myocardial contractility, end-diastolic pre ...
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ConferenceIEEE International Ultrasonics Symposium, IUS · October 31, 2017
Myocardial strain imaging has been shown to add significant prognostic and diagnostic value to echocardiography. While the reliability of ultrasound-based strain measurement techniques has improved considerably in terms of regional consistency and inter-re ...
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ConferenceIEEE International Ultrasonics Symposium, IUS · October 31, 2017
Strain imaging is gaining traction as a means to assess cardiac function by tracking the cyclic deformation of the myocardium. Compared to traditional measures such as ejection fraction, global myocardial strain has been shown to be an earlier and more sen ...
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ConferenceIEEE International Ultrasonics Symposium, IUS · October 31, 2017
High speed ultrasound imaging is a new imaging method particularly applicable to cardiology. At Duke we have developed a real time high speed imaging system capable of producing up to 2500 images per second while maintaining the live imaging feature so ess ...
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ConferenceIEEE International Ultrasonics Symposium, IUS · October 31, 2017
Myocardial elastance, derived from pressure-volume (PV) loops in the left ventricle (LV), can be used to assess LV function and myocardial performance. This method requires an invasive intracardiac pressure-volume catheter to be inserted in the LV, limitin ...
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Journal ArticleUltrasound Med Biol · November 2016
The study describes a novel algorithm for deriving myocardial strain from an entire cardiac cycle using high-frame-rate ultrasound images. Validation of the tracking algorithm was conducted in vitro prior to the application to patient images. High-frame-ra ...
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Journal ArticleJ Am Soc Echocardiogr · November 2016
BACKGROUND: Patients with systemic right ventricles frequently experience progressive heart failure and conduction abnormalities leading to abnormal ventricular activation. Activation delay-induced mechanical dyssynchrony can contribute to ventricular fail ...
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Journal ArticleEur Heart J · July 21, 2016
AIMS: We aimed to determine the frequency of aortic valve surgery (AVR) with or without coronary artery bypass grafting (CABG), among patients with moderate/severe aortic stenosis (AS) and left ventricular systolic dysfunction (LVSD), and its relationship ...
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Journal ArticleJ Am Soc Echocardiogr · April 2016
BACKGROUND: In patients with suspected native valve infective endocarditis, current guidelines recommend initial transthoracic echocardiography (TTE) followed by transesophageal echocardiography (TEE) if clinical suspicion remains. The guidelines do not ac ...
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Journal ArticleJ Am Soc Echocardiogr · March 2016
BACKGROUND: Pediatric dilated cardiomyopathy (DCM) is associated with death or transplantation and is typically considered a homogeneous process affecting global left ventricular (LV) function. However, assessment of regional abnormalities that contribute ...
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Journal ArticleCirc Cardiovasc Imaging · March 2016
BACKGROUND: The management of aortic stenosis rests on accurate echocardiographic diagnosis. Hence, it was chosen as a test case to examine the utility of continuous quality improvement (CQI) approaches to increase echocardiographic data accuracy and relia ...
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ConferenceComputing in Cardiology · March 1, 2016
This study aims to describe a feature tracking algorithm tailored to estimate circumferential strain on high frame rate ultrasound (HFR-US) images. The algorithm used the Hungarian assignment algorithm for tracking a basic feature descriptor. A second orde ...
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Journal ArticleJ Electrocardiol · 2016
BACKGROUND: In contrast to LBBB patients less is known about patients with RBBB+LAFB regarding LV contractile abnormalities and the potential role of CRT. This study investigated whether patients with RBBB+LAFB morphology have echocardiographic mechanical ...
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Conference2015 IEEE International Ultrasonics Symposium, IUS 2015 · November 13, 2015
Myocardial elasticity is an important indicator of cardiac function and is affected in many disorders associated with heart failure. Ultrasound based interrogation of cardiac stiffness has been extensively studied in ex-vivo, open chest and intracardiac im ...
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Journal ArticleIEEE Trans Ultrason Ferroelectr Freq Control · October 2015
We describe an advanced real-time high-speed echocardiographic system with live display while scanning. Images are acquired at rates up to 1000 per second for adult cardiac applications and are stored in computer memory. Images may be played back in slow m ...
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Journal ArticleCrit Pathw Cardiol · September 2015
BACKGROUND: Calcific aortic stenosis (AS) is the most common underlying pathology in patients undergoing heart valve surgery, with an expected increasing prevalence among the aging population. METHODS AND RESULTS: We identified the temporal trends in refer ...
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Journal ArticleJ Am Coll Cardiol · August 11, 2015
BACKGROUND: Current guidelines suggest that patients with left bundle branch block (LBBB) be treated with cardiac resynchronization therapy (CRT); however, one-third do not have a significant activation delay, which can result in nonresponse. By identifyin ...
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Journal ArticleJ Am Soc Echocardiogr · May 2015
BACKGROUND: Speckle-tracking strain is almost universally cited as being independent of angle of insonation, but there are minimal confirmatory studies, and this claim may not be consistent with the known limitations of ultrasound axial and lateral spatial ...
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Journal ArticleAm J Cardiol · January 1, 2015
We aimed to characterize the hemodynamic progression of aortic stenosis (AS) in a contemporary unselected cohort of patients with preserved left ventricular ejection fraction. Current guidelines recommend echocardiographic surveillance of hemodynamic progr ...
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Journal ArticleJ Electrocardiol · 2015
INTRODUCTION: Left bundle branch block (LBBB) is a known complication of transcatheter aortic valve replacement (TAVR) and has been shown to predict worsened outcomes in TAVR patients. A regional longitudinal strain pattern, termed the "classic" pattern of ...
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Journal ArticleJ Electrocardiol · 2015
BACKGROUND: New-onset left bundle branch block (LBBB) is a known complication during Transcatheter Aortic Valve Replacement (TAVR). This study evaluated the influence of pre-TAVR cardiac conditions on left ventricular functions in patients with new persist ...
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Journal Article · January 1, 2015
A more intelligible display of complex cardiac pathology and the need for more accurate left ventricular (LV) function assessment prompted investigators to develop three-dimensional (3D) echocardiography immediately after the introduction of two-dimensiona ...
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ConferenceIEEE International Ultrasonics Symposium, IUS · October 20, 2014
A new method of acquiring and displaying high speed ultrasound images has been developed. To extract flow information from the low intensity reflections of moving blood in these high frame rate images, difference imaging was found to be a particularly appl ...
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Journal ArticleJ Am Soc Echocardiogr · September 2014
BACKGROUND: Progressive heart failure leading to transplantation or death is common in pediatric dilated cardiomyopathy (DCM), and treatment options are limited. Select children with DCM have improved after cardiac resynchronization therapy (CRT), but pred ...
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Journal ArticleJ Am Soc Echocardiogr · June 2014
BACKGROUND: Right ventricular (RV) function is a strong predictor of mortality in pulmonary hypertension (PH), but two-dimensional (2D) echocardiography-derived assessments of RV function that could aid in risk assessment and management of patients with PH ...
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Journal ArticleJ Am Soc Echocardiogr · April 2014
BACKGROUND: Although quantitative right ventricular (RV) strain analysis may be useful in congenital and acquired heart disease populations with RV failure, a comprehensive, standardized approach is lacking. An 18-segment RV strain analysis obtained from t ...
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Journal ArticleJ Cardiothorac Vasc Anesth · February 2014
OBJECTIVE: Perioperative transesophageal echocardiography is essential for decision-making for mitral valve surgery. While two-dimensional transesophageal echocardiography represents the standard of care, tracking of dynamic changes using three-dimensional ...
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Journal ArticlePacing Clin Electrophysiol · November 2013
BACKGROUND: Optimization of the interventricular delay (VV-optimization) in cardiac resynchronization therapy (CRT) patients can be performed by evaluation of mechanical dyssynchrony. However, there is no consensus on which method to use. In this study, th ...
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Journal ArticleUltrasound Med Biol · October 2013
Short-lag spatial coherence (SLSC) imaging is a novel beamforming technique that reduces acoustic clutter in ultrasound images. A clinical study was conducted to investigate clutter reduction and endocardial border detection in cardiac SLSC images. Individ ...
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Journal ArticleAm Heart J · August 2013
BACKGROUND: The relationship between myocardial electrical activation by electrocardiogram (ECG) and mechanical contraction by echocardiography in left bundle-branch block (LBBB) has never been clearly demonstrated. New strict criteria for LBBB based on a ...
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Journal ArticleJACC Cardiovasc Imaging · August 2013
OBJECTIVES: This study sought to hypothesize that global longitudinal strain (GLS) as a measure of infarct size, and mechanical dispersion (MD) as a measure of myocardial deformation heterogeneity, would be of incremental importance for the prediction of s ...
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Journal ArticleEur Heart J · January 2013
AIMS: Pre-implant assessment of longitudinal mechanical dyssynchrony using cross-correlation analysis (XCA) was tested for association with long-term survival and compared with other tissue Doppler imaging (TDI)-derived indices. METHODS AND RESULTS: In 131 ...
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Journal ArticleJ Am Soc Echocardiogr · November 2012
BACKGROUND: Evaluation of myocardial deformation by two-dimensional speckle-tracking is useful for clinical and research purposes. However, differences may exist among different ultrasound machines, software packages, frame rates, and observers. METHODS: T ...
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Journal ArticleAm Heart J · April 2012
BACKGROUND: A classical strain pattern of early contraction in one wall and prestretching of the opposing wall followed by late contraction has previously been associated with left bundle branch block (LBBB) activation and short-term response to cardiac re ...
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Journal ArticleEur J Echocardiogr · February 2011
UNLABELLED: Aim The presence of septal hypertrophy in hypertrophic cardiomyopathy (HCM) is common. To date, there has been no accepted classification of septal morphology in HCM. Furthermore, the possible relationship between septal morphology and clinical ...
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Chapter · December 1, 2009
The mitral valve is the most easily recognized moving structure in the heart. Because of its rapid to and fro motion, the mitral valve serves as home base for almost all echocardiographic examinations. When the transducer is directed posteriorly from the c ...
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Journal Article · December 1, 2009
Masses within the heart are most commonly due to thrombus formation or vegetations associated with endocarditis. Two-dimensional echocardiography is much better than M-mode for the detection and localization of any intracardiac mass. Thrombus formation is ...
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Journal ArticleEchocardiography · December 1, 2009
Echocardiography has expanded greatly to become a sub-specialty in cardiology in its own right. From the original M-mode modality of 50 years ago, it has evolved into a complex multimodality method for evaluating and quantifying cardiovascular lesions. In ...
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Journal ArticleUltrason Imaging · October 2008
A miniature motor rotating at 11,000 rpm was attached onto the proximal end of cardiac electrophysiological (EP) catheters in order to produce vibrations at the tip that were then visualized by color Doppler on ultrasound scanners. The catheter tip was ima ...
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Journal ArticleAm J Cardiol · May 15, 2004
In 107 patients with coronary disease and severe left ventricular dysfunction, we examined the prognostic power of viability identified by dobutamine stress echocardiography. At a mean follow-up of 27 months, patients with viable myocardium who underwent r ...
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Journal ArticleAm Heart J · March 2004
OBJECTIVE: To determine whether internal medicine house staff with limited training in echocardiography can use point-of-care echocardiography to make simple, clinically important diagnoses. BACKGROUND: Availability of small, portable ultrasound devices co ...
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Journal ArticleAm J Cardiol · February 15, 2004
Echocardiograms of 290 patients with dilated cardiomyopathy (ejection fraction < or =35%) were reviewed for the presence of left ventricular (LV) apical abnormalities; outcomes of stroke and death were then correlated with the presence of LV thrombus. Duri ...
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Journal ArticleJ Vasc Surg · October 2002
OBJECTIVE: Neointimal hyperplasia remains a principal cause of vein graft failure. Genetic contributions to vein graft neointimal hyperplasia could be well studied in the mouse; however, surgical approaches to vein bypass surgery in the mouse have yet to r ...
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Journal ArticleJ Cardiol · 2001
BACKGROUND: A novel imaging system has been introduced which uses a dedicated two-dimensional echo probe for rapid beam forming to scan a pyramidal volume in real time. Real-time volumetric echocardiography has the potential to determine accurate cardiovas ...
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Journal ArticleEchocardiography · November 2000
The heart is a dynamic organ with complexities in its shape. As such, it places special demands on three-dimensional techniques for reconstruction. Real-time volumetric echocardiography, which is based on phased array and parallel processing principles to ...
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Journal ArticleAm Heart J · June 2000
BACKGROUND: Although transesophageal echocardiography (TEE) is more sensitive than transthoracic echocardiography (TTE) in detecting echocardiographic evidence of infective endocarditis (IE), the impact of TEE on the clinical diagnosis of IE has not been c ...
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Journal ArticleCirculation · May 2, 2000
BACKGROUND: The combination of fenfluramine and phentermine was a widely used obesity treatment before the withdrawal of fenfluramine for an association with heart valve regurgitation. The prevalence and clinical significance of regurgitation among patient ...
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Journal ArticleJ Am Soc Echocardiogr · March 2000
We evaluated the ability of real-time 3-dimensional (RT3D) echocardiography to diagnose congenital heart defects and its potential for presenting structural abnormalities in novel views. Seventy-five patients with suspected congenital heart defects were ex ...
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Journal ArticleJ Am Soc Echocardiogr · October 1999
Because minimally invasive methods of preload variation are not validated for load-insensitive indexes of cardiac performance, intravenous nitroglycerin (NTG), phenylephrine, and saline solution (VOL) boluses were used in blocked and intact autonomic state ...
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Journal ArticleAm J Cardiol · June 17, 1999
More than 40 different beta-cardiac myosin heavy chain (beta-MHC) missense mutations have been identified that cause familial hypertrophic cardiomyopathy (FHC). Some of these are recognized to have important clinical manifestations, such as an increased in ...
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Journal ArticleAm Heart J · May 1999
BACKGROUND: The asymmetry and complex shape of the right ventricle have made it difficult to determine right ventricular (RV) volume with 2-dimensional echocardiography. Three-dimensional cardiac imaging improves visualization of cardiac anatomy but is als ...
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Journal ArticleJ Am Soc Echocardiogr · January 1999
Accurate characterization of regional wall motion abnormalities requires a thorough evaluation of the entire left ventricle (LV). Although 2-dimensional echocardiography is frequently used for this purpose, the inability of tomographic techniques to record ...
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Journal ArticleCirculation · May 19, 1998
BACKGROUND: The lack of a suitable noninvasive method for assessing right ventricular (RV) volume and function has been a major deficiency of two-dimensional (2D) echocardiography. The aim of our animal study was to test a new real-time three-dimensional ( ...
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Journal ArticleJournal of Cardiovascular Diagnosis and Procedures · January 1, 1998
Matrix array ultrasound is a medical imaging modality in which a 3D volume is scanned electronically without physically moving the transducer, permitting rapid continuous 3D scanning of the heart. Unlike reconstructive 3D ultrasound, which relies on physic ...
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ConferenceProceedings of SPIE - The International Society for Optical Engineering · December 1, 1997
We describe an active contour based on the elliptical Fourier series, and its application to matrix-array ultrasound. Matrix-array ultrasound is a new medical imaging modality that scans a 3D-volume electronically without physically moving the transducer, ...
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Journal ArticleJournal of the American Society of Echocardiography · December 1, 1997
To test the hypothesis that digital echocardiography (DE) is a reliable substitute for video tape (VT) for the interpretation of routine studies, we examined 51 pts with known or suspected cardiac disease. Images of the 4 standard views with and without co ...
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Journal ArticleJ Am Soc Echocardiogr · 1997
To use Albunex as a blood-flow tracer, the stability and consistency of microspheres under mixing conditions must be known. This study examined the effects of mixing conditions and machine settings on the size and echogenicity of Albunex solutions in vitro ...
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Journal ArticleUltrasound Med Biol · 1997
Integrated backscatter and its cyclic variation are potentially important parameters to discriminate normal from diseased myocardium. Cyclic variation of integrated backscatter is expected to be independent of machine settings. Backscatter images of swine ...
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Journal ArticleAm J Cardiol · December 15, 1996
We measured left atrial function during sinus rhythm before and after ventricular tachycardia was induced in an electrophysiology laboratory, using peak transmitral A-wave velocity from pulsed-Doppler transthoracic echocardiography as a marker of left atri ...
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Journal ArticleAm J Cardiol · February 15, 1996
With use of new Duke criteria, 405 episodes of suspected endocarditis were previously classified as "definite," "possible," or "rejected" endocarditis. To determine the negative predictive value of the Duke clinical criteria for the classification of suspe ...
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Journal ArticleJ Am Soc Echocardiogr · 1996
The Frank-Starling relationship between left ventricular stroke work and end-diastolic minor-axis cross-sectional area was evaluated as a load-insensitive measure of inotropic state by two-dimensional echocardiography in 10 conscious dogs. Stroke work was ...
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Journal ArticleAnn Thorac Surg · December 1995
BACKGROUND: This article provides an overview of the application of intraoperative echocardiography during repair of congenital heart defects based on our experience with 1,000 patients. METHODS: The patients in this study all underwent repair of a congeni ...
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Journal ArticleAm Heart J · August 1995
Although it has been shown that a hypotensive response during dobutamine stress echocardiography is not a marker of coronary artery disease, the mechanism of this response remains unclear. We hypothesize that hypotension during dobutamine stress echocardio ...
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Journal ArticleAm Heart J · June 1995
The development of hypotension during various exercise stress tests has been correlated with the presence of multivessel coronary artery disease and impaired left ventricular contractility. Hypotension may also occur during dobutamine stress echocardiograp ...
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Journal ArticleAm J Cardiol · January 1, 1995
Transesophageal echocardiography and diagnostic cardiac catheterization were performed in 36 patients with symptomatic mitral stenosis to assess the incidence and significance of systolic flow reversal in the pulmonary veins. Mitral regurgitation was grade ...
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Journal ArticleJ Am Soc Echocardiogr · 1995
A method for constructing three-dimensional images of flow is described. The technique involves the acquisition of numerous closely spaced planes, each comprised of a map of the two-dimensional velocities measured in that plane. Each such vector velocity m ...
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Journal ArticleJ Am Coll Cardiol · January 1995
OBJECTIVES: This study was performed to examine the effect of dobutamine stress echocardiography on mitral regurgitation and to test the hypothesis that mitral regurgitation will increase in patients with an ischemic response. BACKGROUND: New or worsening ...
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Journal ArticleAm J Cardiol · October 15, 1994
The purpose of this study was twofold: (1) to determine interobserver variability of echocardiographic characteristics of vegetations in patients with infective endocarditis, and (2) to assess the value of these vegetation characteristics in predicting emb ...
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Journal ArticleJ Ultrasound Med · August 1994
An improved cardiac sonographic phantom is described that simulates the anatomy of the human heart for applications as a low cost quality assurance and training tool in echocardiography. The major new feature in the phantom is the development of a polyuret ...
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Journal ArticleAm J Med · March 1994
PURPOSE: This study was designed to develop improved criteria for the diagnosis of infective endocarditis and to compare these criteria with currently accepted criteria in a large series of cases. PATIENTS AND METHODS: A total of 405 consecutive cases of s ...
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Journal ArticleAm J Physiol · January 1994
Serial studies of adaptation to aortic regurgitation (AR) were undertaken to determine whether sonomicrometry and echocardiography could be combined to measure changes in left ventricular (LV) cavitary volume (Vlv) and wall mass using the geometric formula ...
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Journal ArticleAm J Cardiol · December 1, 1993
To determine the usefulness of dobutamine stress echocardiography for detecting restenosis after percutaneous transluminal coronary angioplasty, the results of coronary arteriography and dobutamine stress echocardiography were compared in 103 patients 6 mo ...
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Journal ArticleJ Am Coll Cardiol · November 1, 1993
OBJECTIVES: This study was designed to assess the safety and efficacy of intravenously administered sonicated human serum albumin for enhancing echocardiographic delineation of the left ventricular endocardium and improving assessment of wall motion in pat ...
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Journal ArticleAm J Med · August 1993
PURPOSE: To determine the effectiveness of the preoperative evaluation and overall diagnostic efficacy of subxiphoid pericardial biopsy with fluid drainage in patients with new, large pericardial effusions. DESIGN: A prospective interventional case series ...
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Journal ArticleAm Heart J · June 1993
Echocardiography and thallium-201 imaging with coronary vasodilators such as dipyridamole have been shown to be useful in detecting the presence and prognostic significance of coronary artery disease. Adenosine, a potent and direct coronary vasodilator, ha ...
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Journal ArticleInt J Card Imaging · 1993
Transthoracic two-dimensional and Doppler echocardiography has been well established as a useful technique for evaluating many pathologic processes affecting the thoracic aorta. However, the distance of the aortic arch and descending thoracic aorta from th ...
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Journal ArticleAnn Thorac Surg · October 1992
Our group has previously reported a large prospective experience with the use of intraoperative echocardiography with Doppler color-flow imaging (IE-DCFI) during the repair of congenital heart defects. We have now performed IE-DCFI in 621 patients and have ...
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Journal ArticleAm J Cardiol · April 15, 1992
To determine the clinical features, course and outcome of patients with cardiac tamponade, 57 consecutive patients with new, large pericardial effusions were prospectively studied. Twenty-five patients (44%) developed cardiac tamponade with venous hyperten ...
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Journal ArticleChest · April 1992
To determine the safety, diagnostic value, and clinical outcome of patients with malignancy undergoing subxiphoid pericardiotomy for large pericardial effusions, we prospectively studied 25 consecutive patients with malignancy and new, large pericardial ef ...
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Journal ArticleJ Am Soc Echocardiogr · 1992
The Health Care Financing Administration has released final regulations concerning physician payment reform. The new method will significantly affect global, technical, and professional reimbursement. The American Society of Echocardiography is preparing r ...
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Journal ArticleProceedings of the Annual Conference on Engineering in Medicine and Biology · December 1, 1991
The cardiac anthropomorphic ultrasound phantom is improved by the addition of two new features. An aorta with a bifurcation is molded into the torso via a 'lost wax' procedure. B-scan images of contrast medium and color-flow Doppler images show flow patter ...
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Journal ArticleClin Cardiol · November 1991
This study was designed to identify a concentration of sonicated albumin microspheres that is safe, useful in determining graft patency, and provides an estimate of regional myocardial perfusion. The study included 8 patients between 50 and 72 years of age ...
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Journal ArticleCirculation · August 1991
BACKGROUND: Intraoperative transesophageal Doppler color flow imaging (TDCF) affords the opportunity to assess mitral valve competency immediately before and after cardiopulmonary bypass (CPB). The purpose of this study was to assess the utility of TDCF to ...
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Journal ArticleArch Intern Med · July 1991
The use of ultrasonography in cardiology has progressed so dramatically that not only is anatomic information available but information can also be derived about cardiac hemodynamics. Applications range from intravascular ultrasonic imaging of coronary ath ...
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Journal ArticleAm J Cardiol · April 15, 1991
Validation of catheter-based intravascular ultrasound imaging has been based on comparisons with histology and digital angiography, each of which may have limitations in the assessment of arterial size and morphology. External, high-frequency ultrasound ca ...
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Journal ArticleAm J Cardiol · March 1, 1991
The effect of thrombolytic therapy on the frequency, time course and sequelae of pericardial effusion after myocardial infarction are unknown. A prospective, serial, 2-dimensional echocardiographic study of patients with myocardial infarction who received ...
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Journal ArticleTrends Cardiovasc Med · March 1991
Advancements in echo-Doppler technology now provide the capability for both high-quality anatomic imaging as well as the assessment of cardiac flows and hemodynamics. Given these capabilities, and the potentially complex nature of all congenital heart lesi ...
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Journal ArticleAm Heart J · January 1991
The diagnostic accuracy of Doppler color flow imaging in the diagnosis of postinfarction ventricular septal defects has not been established. In this study, 43 patients with unexplained hypotension or a new murmur in the periinfarct period were evaluated w ...
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Journal ArticleEchocardiography · January 1991
The purpose of this article is to review new approaches to three-dimensional acquisition and presentation of echocardiographic data. New three-dimensional phased-array devices hold great promise for the development and application of new descriptors for le ...
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Journal ArticleJ Am Soc Echocardiogr · 1991
The article by McDonald et al. points out the widespread demand for preliminary reporting of echocardiographic data by sonographers, at least in the setting of physicians in training. Such preliminary reporting is illegal in most states because it constitu ...
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Journal ArticleJ Thorac Cardiovasc Surg · August 1990
Routine epicardial two-dimensional echocardiography, Doppler, and Doppler color flow imaging studies were performed before and after cardiopulmonary bypass in 328 patients undergoing operations for congenital heart disease. Ages ranged from 1 day to 59 yea ...
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Journal ArticleEur Heart J · April 1990
Regurgitant jets were simulated in vitro and analysed using Doppler colour flow imaging. The regurgitant volumes were estimated using total jet area (JA), variance area (VA), and the maximum area of variance x time to maximum area of variance (MAVT). Both ...
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Journal ArticleJ Am Coll Cardiol · April 1990
To assess the relation of quantitative measures of coronary stenoses to the development of exercise-induced regional wall motion abnormalities, 34 patients with isolated, single vessel coronary artery lesions and normal wall motion at rest underwent exerci ...
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Journal ArticleJ Thorac Cardiovasc Surg · March 1990
Intraoperative evaluation of the effectiveness of myocardial revascularization has been limited by an inability to assess regional myocardial perfusion. Microbubbles of sonicated diatrizoate sodium and diatrizoate meglumine (Renografin) have been an effect ...
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Journal ArticleJ Am Coll Cardiol · February 1990
To assess the value of intraoperative transesophageal echocardiography during cardiac valve surgery, 154 consecutive patients who had a valve operation in conjunction with pre- and postcardiopulmonary bypass transesophageal imaging were studied. Prebypass ...
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Journal ArticleChest · February 1990
The presence of left ventricular outflow tract obstruction (LVOTO) of either a resting or dynamic nature may have important therapeutic and prognostic implications in patients with hypertrophic cardiomyopathy (HCM). Doppler echocardiograms combined with am ...
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Journal ArticleJ Am Soc Echocardiogr · 1990
Some Medicare carriers have independently decided to treat all billings for echocardiographic services as radiologic, whereas others have decided to treat billings from multispecialty practices that include a radiologist as radiologic services. The result ...
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Journal ArticleAnn Surg · October 1989
Surgical repair of congenital cardiac defects (CCD) has undergone a remarkable evolution in the past decade. Major defects are now often completely corrected in early infancy with continually improving rates of survival. It has become clear that the next m ...
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Journal ArticleEur Heart J · September 1989
Comparison of two-dimensional echocardiography and right ventricular angiographic findings was carried out in patients with arrhythmogenic right ventricular dysplasia. Diagnosis was based on ECG and angiographic criteria in all cases. Echo and angiographic ...
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Journal ArticleJ Thorac Cardiovasc Surg · July 1989
The use of intraoperative epicardial Doppler echocardiography with color flow imaging both before and after cardiopulmonary bypass to assist repair of congenital heart defects in infants and small children has not been reported. To demonstrate its simplici ...
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Journal ArticleAm J Cardiol · June 1, 1989
Doppler mitral flow indexes and their relation to invasively measured hemodynamic diastolic indexes were assessed in 13 patients with isolated aortic stenosis (AS), and compared to Doppler indexes in 10 normal subjects matched for age, heart rate, left ven ...
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Journal ArticleLancet · March 11, 1989
30 patients with a history of decompression sickness were examined for the presence of patent foramen ovale by bubble contrast, two-dimensional echocardiography and colour flow doppler imaging. With bubble contrast, 11 (37%) of the patients had right-to-le ...
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Journal ArticleAm Heart J · March 1989
Doppler color flow and two-dimensional ultrasonographic images of the femoral region were obtained in 25 patients referred for suspected vascular complications of cardiac catheterization. Five patients had normal findings, while 23 abnormalities were noted ...
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Journal ArticleAm Heart J · February 1989
The relationship between dynamic changes in aortic valve gradient and left ventricular ejection performance in the early period after successful percutaneous aortic valvuloplasty has not been described in detail. Accordingly 20 adult patients with severe s ...
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Journal ArticleJ Am Soc Echocardiogr · 1989
Detection of the proximal left and right coronary arteries is possible by transesophageal echocardiography with rather high frequencies. The proximal left coronary artery can be detected in 86% of patients and the proximal right in 82%. Precise identificat ...
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Journal ArticleAm J Cardiol · 1989
CLINICAL PERSPECTIVE: The first prospective trial in which both echocardiography and Doppler color flow imaging (echo-DCFI) are used routinely during surgery for congenital heart lesions has been undertaken at Duke Medical Center. Precardiopulmonary bypass ...
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Journal ArticleJ Am Soc Echocardiogr · 1989
Medicare reimbursement for echocardiographic procedures is clouded by the fact that Medicare defines ultrasound services to be "radiologic." As such, a 40% limitation has been imposed in some states. In addition, as a result of the Omnibus Budget Reconcili ...
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Journal ArticleAmerican Journal of Physiology - Heart and Circulatory Physiology · December 1, 1988
Several geometric algorithms have been applied to estimate left ventricular wall volume (V(wall)) from two-dimensional echocardiograms but have not been validated in eccentrically hypertrophied hearts. These algorithms can be fitted to the general formula: ...
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Journal ArticleJ Am Soc Echocardiogr · 1988
The Omnibus Budget Reconciliation Act of 1987 has significantly changed the rules governing the way in which charges must be made to Medicare concerning certain tests, including ultrasound, by a physician who provides these tests by means of an outside sup ...
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Journal ArticleJ Am Soc Echocardiogr · 1988
When a sonographer renders diagnostic interpretations from echocardiographic data, the possibility exists that state statutes concerning the unauthorized practice of medicine may be violated. Problems likely exist in this regard when the sonographer render ...
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Journal ArticleCirculation · August 1987
According to the thoracic pump model of cardiopulmonary resuscitation (CPR), the heart serves as a passive conduit for blood flow from the pulmonary to the systemic vasculature, necessitating an open mitral valve and anterograde transmitral blood flow duri ...
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Journal ArticleJ Am Coll Cardiol · June 1987
On the hypothesis that Doppler ultrasound fails to penetrate prosthetic valves, an in vitro flow simulation system was constructed in a large water tank. Conventional pulsed, continuous wave and Doppler color flow systems were used to detect flow in tubing ...
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Journal ArticleAnesth Analg · May 1987
Transesophageal Doppler color flow mapping (TEDCFM) is a new ultrasound modality now being developed. It provides a convenient, noninvasive way to image cardiac anatomy and intracardiac blood flow that is applicable to intraoperative use. We describe its u ...
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Journal ArticleAm Heart J · March 1987
The accuracy of in vivo measurements of left ventricular wall thickness and chamber size by means of two-dimensional echocardiography was investigated by comparing left ventricular mass estimates obtained at end diastole in 15 closed-chest dogs with a wide ...
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Journal ArticleStroke · 1987
Patient records in 36 consecutively identified patients with typical echocardiographic findings of atrial septal aneurysm were reviewed. Ten of the 36 (28%) had cerebrovascular events. Of these 10, 5 had completed strokes of definite embolic origin on the ...
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Journal ArticleJ Am Coll Cardiol · June 1986
A necessary percursor to real-time three-dimensional echocardiographic imaging is the ability to obtain multiple planes of acoustic data simultaneously. A new ultrasound imaging technique facilitates the display of two real-time orthogonal B-mode images (O ...
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Journal ArticleJ Am Coll Cardiol · May 1986
Nine consecutive patients with penetrating missile wounds of the heart were evaluated by M-mode and two-dimensional echocardiography for localization of retained missile fragments noted to be moving in synchrony with the heart by fluoroscopy. Echocardiogra ...
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Journal ArticleAm J Cardiol · February 1, 1986
Adequate contrast 2-dimensional (2-D) echocardiograms were recorded in 13 to 16 patients with typical 2-D findings of atrial septal aneurysm. Five patients were referred for detection of intracardiac source of emboli after embolic stroke and 11 were evalua ...
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Journal ArticleJ Am Coll Cardiol · November 1985
Disruption of the posterior mitral anulus is a rare complication of mitral valve replacement that may result in subvalvular left ventricular pseudoaneurysm formation. Such pseudoaneurysm formation was easily recognized by two-dimensional echocardiography i ...
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Journal ArticleJ Am Coll Cardiol · November 1985
Two patients with recent inferior myocardial infarction were found by two-dimensional and Doppler echocardiography to have both an inferior wall pseudoaneurysm and a contiguous rupture of the posterior ventricular septum. The pseudoaneurysm was not suspect ...
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Journal ArticleMedicine (Baltimore) · November 1985
Cardiac illness in myotonic muscular dystrophy (MyD) is infrequent, but subclinical cardiac involvement in MyD is very common (found in 42 of 46 subjects) and may be responsible for sudden death. In this series, we found ECG abnormalities in 72%, left vent ...
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Journal ArticleAm Heart J · October 1985
To further define the clinical role of continuous wave Doppler echocardiography for determining aortic valve gradient, we studied 60 consecutive adult patients (age range 22 to 81 years, mean age 63) with suspected aortic stenosis within 24 hours of cathet ...
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Journal ArticleJ Thorac Cardiovasc Surg · August 1985
Nonischemic ventricular tachycardia most commonly arises in the right ventricular free wall and is frequently refractory to medical therapy. Many different types of surgical procedures have been employed to treat medically refractory nonischemic ventricula ...
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Journal ArticleAm J Cardiol · June 1, 1985
Comparison of 2-dimensional (2-D) echocardiographic and right ventricular (RV) angiographic findings was performed in 10 patients with arrhythmogenic RV dysplasia. Diagnosis was based on accepted electrocardiographic and angiographic criteria. Nine patient ...
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Journal ArticleEchocardiography · January 1, 1985
Two-dimensional real-time Doppler color flow mapping methods are early in their course of clinical use and further experience is obviously required to realize the full potential of this method for the evaluation of stenotic valvular lesions. Many new syste ...
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Journal ArticleUltrasound Med Biol · 1984
To test the hypothesis that pulsed Doppler ultrasound spectral properties of bounded fluid jets related to orifice size, in vitro examinations were performed using a hydraulic simulator (standpipe, compliant receiving chamber, and variable round orifice). ...
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Journal ArticleJ Am Coll Cardiol · January 1984
The results of a survey of 363 physicians performing echocardiography were evaluated to assess the relative safety of contrast echocardiography. Fifteen physicians reported a variety of transient side effects, including neurologic and respiratory symptoms. ...
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Journal ArticleRadiol Clin North Am · December 1983
The Cardiac Diagnostic Unit at Duke University Hospital brings together multiple diagnostic services for evaluation of patients with cardiovascular disease. This Unit is a combined effort of the departments of Medicine, Radiology, Surgery, Bioengineering, ...
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Journal ArticleHerz · October 1983
Echocardiography may detect the presence of vegetative lesions in between 55 and 80% of patients with the clinical syndrome of bacterial endocarditis. While the mere presence of vegetations does not alone warrant surgical intervention in patients with this ...
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Journal ArticleCirculation · February 1982
This paper provides guidelines for the optimal, rather than minimal, performance of ultrasonic examination of the heart for current clinical applications using conventional echocardiographic equipment. Since the original report of this Inter-Society Commis ...
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Journal ArticleJ Thorac Cardiovasc Surg · September 1981
Technical advances in cardiac surgery have made accessible previously remote regions within the heart and great vessels; nevertheless, limitations in the ability to locate intramyocardial foreign bodies with precision utilizing conventional radiographic te ...
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Journal ArticleCirculation · May 1981
Contrast M-mode and two-dimensional ultrasonography of the inferior vena cava were performed in 65 patients with various acquired and congenital cardiac disorders. After saline was injected into a peripheral arm vein, the inferior vena cava was visualized ...
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Journal ArticleCirculation · February 1981
The capability of a pulsed Doppler flowmeter combined with a phased-array imaging system to measure volume flow was tested in vitro and in patients undergoing cardiac catheterization. The Doppler-phased-array system (DPA) was used to determine vessel diame ...
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Journal ArticleAm J Cardiol · December 18, 1980
Two dimensional echocardiography, because of its wide field of view, has been shown to be superior to the M mode approach for ultrasonic evaluation of the left ventricle. The use of this technique for determination of ventricular volume estimates and detec ...
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Journal ArticleRadiology · December 1980
The significance of coronary artery calcification was assessed in 800 patients who underwent cardiac fluoroscopy and selective coronary cineangiography. Calcification was shown by fluoroscopy in 250, of whom 236 (94%) had greater than or equal to 75% steno ...
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Journal ArticleCirculation · February 1980
Eighty-seven patients with the clinical syndrome of infective endocarditis were examined by M-mode and two-dimensional echocardiography. Patients were divided into two groups based on the presence or absence of echocardiographically detected vegetative les ...
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Journal ArticleJ Clin Ultrasound · October 1979
One hundred seventy adult patients with possible congenital or valvular heart disease underwent contrast two-dimensional echocardiographic examination as part of a precatheterization evaluation. Persistent left superior vena cava was detected in 5 patients ...
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Journal ArticleCirculation · February 1979
Two-dimensional echocardiography (2-D echo) was used with peripherally injected contrast material to detect interatrial shunts in 33 patients. Group 1 consisted of 11 patients having classic clinical findings of atrial septal defect. Group 2 consisted of 1 ...
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Journal ArticleActa Med Scand Suppl · 1979
Proper clinical use of real-time, two-dimensional echocardiography depends upon three major factors: the clinical questions posed of these imaging devices, the interrelationship of this technique with other imaging techniques and the quality of the ultraso ...
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Journal ArticleCirculation · December 1978
Four hundred M-mode echocardiographic surveys were distributed to determine interobserver variability in M-mode echocardiographic measurements. This was done with a view toward examining the need and determining the criteria for standardization of measurem ...
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Journal ArticleCirculation · May 1978
Three-year survival for 163 consecutive medically treated patients with 50% or greater left main stenosis was 50%. Survival was significantly higher for patients with 50 to 70% left main stenosis (one and three-year survivals of 91% and 66%) than for patie ...
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Journal ArticleCirculation · January 1978
"Contrast echocardiography", utilizing a two-dimensional ultrasound system and peripheral venous injections, was used for the detection of tricuspid regurgitation in 30 patients. The appearance of contrast in the inferior vena cava and the back and forth m ...
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Journal ArticleCirculation · January 1978
A cohort of 1472 patients who underwent both exercise stress testing and coronary angiography within six weeks was examined. The data indicated that a combination of exercise parameters is both diagnostically and prognostically important. Almost all patien ...
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Journal ArticleStroke · 1978
Initial clinical results are reported from a new real time, 2-dimensional ultrasound scanner modified for adult cephalic applications. An optimized transducer design and the use of the dynamically focused phased array imaging system have resulted in ultras ...
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Journal ArticleCirculation · September 1977
Two-dimensional echocardiographic findings in a group of 24 patients with atrial septal defects were correlated with findings obtained by cardiac catheterization and M-mode echocardiography. The prevalence of mitral prolapse was 95% by two-dimensional echo ...
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Journal ArticleAm J Med · July 1977
A two-dimensional ultrasound imaging system capable of producing high resolution, cross-sectional images of the heart in real-time has been developed. This system relies upon phased-array principles to rapidly steer and focus the ultrasound beam through th ...
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Journal ArticleCirculation · February 1977
Real-time, two-dimensional echocardiography was used to document the presence and assess the size and location of vegetative lesions of the cardiac valves and chambers in seven patients with bacterial endocarditis. Anatomic correlation (surgical or autopsy ...
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Journal ArticleCirculation · January 1977
Left ventricular wall motion was assessed in 105 consecutive patients both invasively, using biplane cineangiography, and noninvasively, by a real-time, phased-array, two-dimensional echocardiography system. Ventricular wall motion in five anatomic areas o ...
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Journal ArticleYale J Biol Med · 1977
This report describes the operating characteristics and initial clinical results of a new echocardiographic system that produces real-time, high resolution, cross-sectional images of the heart. This system relies upon phased-array principles to rapidly ste ...
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Journal ArticleCirculation · January 1977
A real-time, phased-array, two-dimensional echocardiography system was used to assess mitral valve motion in 30 catheterized patients with pure mitral stenosis. Suitable images for analysis of mitral valve motion were obtained in 25 patients. The valve lea ...
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Journal ArticleCirculation · November 1976
In order to define baseline descriptive criteria for the diagnosis of mitral valve prolapse with cross-sectional echocardiography, 49 patients undergoing catheterization were examined by a real-time, two-dimensional phased array echocardiographic imaging s ...
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Journal ArticleAm J Cardiol · October 1976
Standard M mode echocardiography and a new real time two dimensional echocardiographic imaging system were utilized to follow the progressive anatomic destruction of the tricuspid valve in a patient with bacterial endocarditis. The initial two dimensional ...
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Journal ArticleCirculation · February 1976
A new two-dimensional ultrasound imaging system capable of producing high resolution tomographic images of the heart in real time has been developed. This system relies on phased array principles to rapidly steer the ultrasound beam through the structures ...
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Journal ArticleCathet Cardiovasc Diagn · 1976
The development of a ventricular septal defect (VSD) following myocardial infarction is an uncommon complication which clinically can be confused with mitral insufficiency due to infarction of a papillary muscle. The clinical and hemodynamic records of six ...
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Journal ArticleCirculation · October 1975
Echocardiographic and cardiac catheterization findings were compared in 61 patients with mitral stenosis without other significant lesions in an attempt to determine the clinical usefulness of echocardiography in the assessment of such patients. There was ...
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Journal ArticleCirculation · April 1975
The echocardiograms of 46 patients with aortic insufficiency which manifested typical high frequency vibrations of the anterior mitral valve leaflet were reviewed. All patients had overt clinical evidence of aortic insufficiency which was confirmed by angi ...
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Journal ArticleEXCERPTA MEDICA, ICS NO. 363 · January 1, 1975
This report describes the design considerations, performance characteristics and initial clinical results of a new, high-resolution, real-time, two-dimensional ultrasound sector scanner designed specifically for cardiac use. Such a system is unique as it r ...
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Journal ArticleAcoust Hologr · January 1, 1975
Real-time imaaging system is described that relies on phased array principles to steer and focus the ultrasound beam in the near field of a linear array of ultrasound transducers. Underlying the development of this system were several design considerations ...
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Journal ArticleSPIE Semin Proc · January 1, 1975
This report describes the design considerations, performance characteristics and initial clinical results of a new, high-resolution, real-time, two-dimensional ultrasound sector scanner designed specifically for cardiac use. Such a system is unique as it r ...
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Journal ArticleSPIE Semin Proc · January 1, 1974
A description is given of an ultrasound imaging system which permits visualization of two-dimensional cardiac anatomy in real time. This system relies on phased array principles rather than mechanical means to rapidly steer the ultrasound beam through the ...
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