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Joseph Andrew Kisslo

Professor of Medicine
Medicine, Cardiology
Duke Box 3818, Durham, NC 27710
3348A Hosp South, Durham, NC 27710

Selected Publications


Evaluation of Myocardial Stiffness in Cardiac Amyloidosis Using Acoustic Radiation Force Impulse and Natural Shear Wave Imaging.

Journal Article Ultrasound Med Biol · August 2023 OBJECTIVE: Increased myocardial stiffness (MS) is an important hallmark of cardiac amyloidosis (CA) caused by myocardial amyloid deposition. Standard echocardiography metrics assess MS indirectly via downstream effects of cardiac stiffening. The ultrasound ... Full text Link to item Cite

Immersion-Induced Mitral Regurgitation: A Novel Risk Factor for Swimming-Induced Pulmonary Edema.

Journal Article Chest · March 2022 Immersion pulmonary edema, more commonly referred to as swimming-induced pulmonary edema (SIPE), is a well-documented condition believed to be a result of immersion physiologic condition that is characterized by a peripheral-to-central redistribution of bl ... Full text Link to item Cite

Left bundle branch block without a typical contraction pattern is associated with increased risk of ventricular arrhythmias in cardiac resynchronization therapy patients.

Journal Article Int J Cardiovasc Imaging · June 2021 Cardiac resynchronization therapy (CRT) reduces the risk of ventricular arrhythmias (VA) in heart failure (HF) patients with left bundle branch block (LBBB) while the effect is less clear among non-LBBB patients. This study aimed to investigate if absence ... Full text Link to item Cite

Left bundle-branch block is associated with asimilar dyssynchronous phenotype in heart failure patients with normal and reduced ejection fractions.

Journal Article Am Heart J · January 2021 BACKGROUND: Few therapies improve outcomes in patients with heart failure with preserved ejection fraction (HFpEF). If left bundle-branch block (LBBB) is associated with left ventricular dyssynchrony and impaired cardiac performance in HFpEF, cardiac resyn ... Full text Link to item Cite

Predicting the Development of Reduced Left Ventricular Ejection Fraction in Patients With Left Bundle Branch Block.

Journal Article Am J Cardiol · December 15, 2020 Left bundle branch block (LBBB) increases the likelihood of developing reduced left ventricular (LV) ejection fraction (EF) but predicting which patients with LBBB and normal LVEF will develop decreased LVEF remains challenging. Fifty patients with LBBB an ... Full text Link to item Cite

Concomitant changes in ventricular depolarization and repolarization and long-term outcomes of biventricular pacing.

Journal Article Pacing Clin Electrophysiol · November 2020 BACKGROUND: Biventricular (BiV) pacing increases transmural repolarization heterogeneity due to epicardial to endocardial conduction from the left ventricular (LV) lead. However, limited evidence is available on concomitant changes in ventricular depolariz ... Full text Link to item Cite

Early impairment of myocardial deformation assessed by regional speckle-tracking echocardiography in the indeterminate form of Chagas disease without fibrosis detected by cardiac magnetic resonance.

Journal Article PLoS Negl Trop Dis · November 2020 UNLABELLED: Chagas disease (CD) will account for 200,000 cardiovascular deaths worldwide over the next 5 years. Early detection of chronic Chagas cardiomyopathy (CCC) is a challenge. We aimed to test if speckle-tracking echocardiography (STE) can detect in ... Full text Link to item Cite

Contractile Fronts In The Interventricular Septum: A Case For High Frame Rate Echocardiographic Imaging.

Journal Article Ultrasound Med Biol · September 2020 The real time high frame rate (HFR) 2-dimensional ultrasound system, T5, at Duke University is capable of imaging at up to 1000 images per second for adult cardiac imaging. A method for detecting and visualizing the mechanical contraction fronts using HFR ... Full text Link to item Cite

Early cardiac dysfunction in children and young adults with perinatally acquired HIV.

Journal Article AIDS · March 15, 2020 OBJECTIVE: To define the prevalence of early cardiac dysfunction in children and young adults with perinatally acquired HIV and predictors of cardiac function. DESIGN: Cross-sectional design. METHODS: Early cardiac dysfunction was defined as left ventricul ... Full text Link to item Cite

PR Prolongation predicts inadequate resynchronization with biventricular pacing in left bundle branch block.

Journal Article Pacing Clin Electrophysiol · November 2019 BACKGROUND: PR interval prolongation is associated with poor outcome after cardiac resynchronization therapy (CRT) among patients with left bundle branch block (LBBB) but the mechanisms are unknown. We investigated clinical outcomes, electrocardiogram (ECG ... Full text Link to item Cite

Non-invasively quantified changes in left ventricular activation predict outcomes in patients undergoing cardiac resynchronization therapy.

Journal Article J Cardiovasc Electrophysiol · November 2019 BACKGROUND: Changes in left ventricular (LV) activation after cardiac resynchronization therapy (CRT) influence survival but are difficult to quantify noninvasively. METHODS AND RESULTS: We studied 527 CRT patients to assess whether noninvasive quantificat ... Full text Link to item Cite

Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension.

Journal Article Am J Cardiol · October 15, 2019 Echocardiography is a key tool in the management of patients with pulmonary arterial hypertension (PAH), but many potential parameters could be used to assess response to therapy. In this retrospective study of 48 patients with severe PAH at baseline, we e ... Full text Link to item Cite

Index of contractile asymmetry improves patient selection for CRT: a proof-of-concept study.

Journal Article Cardiovasc Ultrasound · October 10, 2019 BACKGROUND: Nearly one-third of heart failure (HF) patients do not respond to cardiac resynchronization therapy (CRT) despite having left bundle branch block (LBBB). The aim of the study was to investigate a novel method of quantifying left ventricular (LV ... Full text Link to item Cite

The Association of a classical left bundle Branch Block Contraction Pattern by vendor-independent strain echocardiography and outcome after cardiac resynchronization therapy.

Journal Article Cardiovasc Ultrasound · May 21, 2019 BACKGROUND: The association of a Classical left bundle branch block (LBBB) contraction pattern and better outcome after cardiac resynchronization therapy (CRT) has only been studied using vendor-specific software for echocardiographic speckle-tracked longi ... Full text Link to item Cite

Quantitative Parameters of High-Frame-Rate Strain in Patients with Echocardiographically Normal Function.

Journal Article Ultrasound Med Biol · May 2019 Recently, we developed a high-frame-rate echocardiographic imaging system capable of acquiring images at rates up to 2500 per second. High imaging rates were used to quantify longitudinal strain parameters in patients with echocardiographically normal func ... Full text Link to item Cite

Non-invasive Measurement of Dynamic Myocardial Stiffness Using Acoustic Radiation Force Impulse Imaging.

Journal Article Ultrasound Med Biol · May 2019 Myocardial stiffness exhibits cyclic variations over the course of the cardiac cycle. These trends are closely tied to the electromechanical and hemodynamic changes in the heart. Characterization of dynamic myocardialstiffness can provide insights into the ... Full text Link to item Cite

Predictors and Changes in Cardiac Hemodynamics and Geometry With Transcatheter Aortic Valve Implantation.

Journal Article Am J Cardiol · March 1, 2019 The introduction of transcatheter aortic valve implantation (TAVI) has revolutionized the treatment of patients with severe aortic stenosis (AS). However, despite the great clinical success of TAVI, less is known about the cardiac hemodynamics and structur ... Full text Link to item Cite

Vectorcardiographic QRS area is associated with long-term outcome after cardiac resynchronization therapy.

Journal Article Heart Rhythm · February 2019 BACKGROUND: Recent studies have suggested that vectorcardiographic measures predict left ventricular (LV) reverse remodeling and clinical outcome in patients receiving cardiac resynchronization therapy (CRT). OBJECTIVES: The objectives of this study were t ... Full text Link to item Cite

Evaluation of Myocardial Stiffness in Cardiac Amyloidosis Using Acoustic Radiation Force Impulse and Natural Shear Wave Imaging.

Journal Article Ultrasound Med Biol · August 2023 OBJECTIVE: Increased myocardial stiffness (MS) is an important hallmark of cardiac amyloidosis (CA) caused by myocardial amyloid deposition. Standard echocardiography metrics assess MS indirectly via downstream effects of cardiac stiffening. The ultrasound ... Full text Link to item Cite

Immersion-Induced Mitral Regurgitation: A Novel Risk Factor for Swimming-Induced Pulmonary Edema.

Journal Article Chest · March 2022 Immersion pulmonary edema, more commonly referred to as swimming-induced pulmonary edema (SIPE), is a well-documented condition believed to be a result of immersion physiologic condition that is characterized by a peripheral-to-central redistribution of bl ... Full text Link to item Cite

Left bundle branch block without a typical contraction pattern is associated with increased risk of ventricular arrhythmias in cardiac resynchronization therapy patients.

Journal Article Int J Cardiovasc Imaging · June 2021 Cardiac resynchronization therapy (CRT) reduces the risk of ventricular arrhythmias (VA) in heart failure (HF) patients with left bundle branch block (LBBB) while the effect is less clear among non-LBBB patients. This study aimed to investigate if absence ... Full text Link to item Cite

Left bundle-branch block is associated with asimilar dyssynchronous phenotype in heart failure patients with normal and reduced ejection fractions.

Journal Article Am Heart J · January 2021 BACKGROUND: Few therapies improve outcomes in patients with heart failure with preserved ejection fraction (HFpEF). If left bundle-branch block (LBBB) is associated with left ventricular dyssynchrony and impaired cardiac performance in HFpEF, cardiac resyn ... Full text Link to item Cite

Predicting the Development of Reduced Left Ventricular Ejection Fraction in Patients With Left Bundle Branch Block.

Journal Article Am J Cardiol · December 15, 2020 Left bundle branch block (LBBB) increases the likelihood of developing reduced left ventricular (LV) ejection fraction (EF) but predicting which patients with LBBB and normal LVEF will develop decreased LVEF remains challenging. Fifty patients with LBBB an ... Full text Link to item Cite

Concomitant changes in ventricular depolarization and repolarization and long-term outcomes of biventricular pacing.

Journal Article Pacing Clin Electrophysiol · November 2020 BACKGROUND: Biventricular (BiV) pacing increases transmural repolarization heterogeneity due to epicardial to endocardial conduction from the left ventricular (LV) lead. However, limited evidence is available on concomitant changes in ventricular depolariz ... Full text Link to item Cite

Early impairment of myocardial deformation assessed by regional speckle-tracking echocardiography in the indeterminate form of Chagas disease without fibrosis detected by cardiac magnetic resonance.

Journal Article PLoS Negl Trop Dis · November 2020 UNLABELLED: Chagas disease (CD) will account for 200,000 cardiovascular deaths worldwide over the next 5 years. Early detection of chronic Chagas cardiomyopathy (CCC) is a challenge. We aimed to test if speckle-tracking echocardiography (STE) can detect in ... Full text Link to item Cite

Contractile Fronts In The Interventricular Septum: A Case For High Frame Rate Echocardiographic Imaging.

Journal Article Ultrasound Med Biol · September 2020 The real time high frame rate (HFR) 2-dimensional ultrasound system, T5, at Duke University is capable of imaging at up to 1000 images per second for adult cardiac imaging. A method for detecting and visualizing the mechanical contraction fronts using HFR ... Full text Link to item Cite

Early cardiac dysfunction in children and young adults with perinatally acquired HIV.

Journal Article AIDS · March 15, 2020 OBJECTIVE: To define the prevalence of early cardiac dysfunction in children and young adults with perinatally acquired HIV and predictors of cardiac function. DESIGN: Cross-sectional design. METHODS: Early cardiac dysfunction was defined as left ventricul ... Full text Link to item Cite

PR Prolongation predicts inadequate resynchronization with biventricular pacing in left bundle branch block.

Journal Article Pacing Clin Electrophysiol · November 2019 BACKGROUND: PR interval prolongation is associated with poor outcome after cardiac resynchronization therapy (CRT) among patients with left bundle branch block (LBBB) but the mechanisms are unknown. We investigated clinical outcomes, electrocardiogram (ECG ... Full text Link to item Cite

Non-invasively quantified changes in left ventricular activation predict outcomes in patients undergoing cardiac resynchronization therapy.

Journal Article J Cardiovasc Electrophysiol · November 2019 BACKGROUND: Changes in left ventricular (LV) activation after cardiac resynchronization therapy (CRT) influence survival but are difficult to quantify noninvasively. METHODS AND RESULTS: We studied 527 CRT patients to assess whether noninvasive quantificat ... Full text Link to item Cite

Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension.

Journal Article Am J Cardiol · October 15, 2019 Echocardiography is a key tool in the management of patients with pulmonary arterial hypertension (PAH), but many potential parameters could be used to assess response to therapy. In this retrospective study of 48 patients with severe PAH at baseline, we e ... Full text Link to item Cite

Index of contractile asymmetry improves patient selection for CRT: a proof-of-concept study.

Journal Article Cardiovasc Ultrasound · October 10, 2019 BACKGROUND: Nearly one-third of heart failure (HF) patients do not respond to cardiac resynchronization therapy (CRT) despite having left bundle branch block (LBBB). The aim of the study was to investigate a novel method of quantifying left ventricular (LV ... Full text Link to item Cite

The Association of a classical left bundle Branch Block Contraction Pattern by vendor-independent strain echocardiography and outcome after cardiac resynchronization therapy.

Journal Article Cardiovasc Ultrasound · May 21, 2019 BACKGROUND: The association of a Classical left bundle branch block (LBBB) contraction pattern and better outcome after cardiac resynchronization therapy (CRT) has only been studied using vendor-specific software for echocardiographic speckle-tracked longi ... Full text Link to item Cite

Quantitative Parameters of High-Frame-Rate Strain in Patients with Echocardiographically Normal Function.

Journal Article Ultrasound Med Biol · May 2019 Recently, we developed a high-frame-rate echocardiographic imaging system capable of acquiring images at rates up to 2500 per second. High imaging rates were used to quantify longitudinal strain parameters in patients with echocardiographically normal func ... Full text Link to item Cite

Non-invasive Measurement of Dynamic Myocardial Stiffness Using Acoustic Radiation Force Impulse Imaging.

Journal Article Ultrasound Med Biol · May 2019 Myocardial stiffness exhibits cyclic variations over the course of the cardiac cycle. These trends are closely tied to the electromechanical and hemodynamic changes in the heart. Characterization of dynamic myocardialstiffness can provide insights into the ... Full text Link to item Cite

Predictors and Changes in Cardiac Hemodynamics and Geometry With Transcatheter Aortic Valve Implantation.

Journal Article Am J Cardiol · March 1, 2019 The introduction of transcatheter aortic valve implantation (TAVI) has revolutionized the treatment of patients with severe aortic stenosis (AS). However, despite the great clinical success of TAVI, less is known about the cardiac hemodynamics and structur ... Full text Link to item Cite

Vectorcardiographic QRS area is associated with long-term outcome after cardiac resynchronization therapy.

Journal Article Heart Rhythm · February 2019 BACKGROUND: Recent studies have suggested that vectorcardiographic measures predict left ventricular (LV) reverse remodeling and clinical outcome in patients receiving cardiac resynchronization therapy (CRT). OBJECTIVES: The objectives of this study were t ... Full text Link to item Cite

Crowdsourcing consensus: proposal of a novel method for assessing accuracy in echocardiography interpretation.

Journal Article Int J Cardiovasc Imaging · November 2018 Quality in stress echocardiography interpretation is often gauged against coronary angiography (CA) data but anatomic obstructive coronary disease on CA is an imperfect gold standard for a stress induced wall motion abnormality. We examined the utility of ... Full text Link to item Cite

Long-term outcomes of mitral regurgitation by type and severity.

Journal Article Am Heart J · September 2018 BACKGROUND: We aimed to determine the association of MR severity and type with all-cause death in a large, real-world, clinical setting. METHODS: We reviewed full echocardiography studies at Duke Echocardiography Laboratory (01/01/1995-12/31/2010), classif ... Full text Link to item Cite

Clinical and Echocardiographic Predictors of Outcomes in Patients With Pulmonary Hypertension.

Journal Article Am J Cardiol · September 1, 2018 In pulmonary hypertension (PH), measurement of various echocardiographic parameters that assess right heart function is recommended by current clinical guidelines. Limited data exists on the combined value of clinical and echocardiographic parameters in pr ... Full text Link to item Cite

Effect of Transmit Beamforming on Clutter Levels in Transthoracic Echocardiography.

Journal Article Ultrason Imaging · July 2018 Transmit beamforming has a strong impact on several factors that govern image quality, field-of-view, and frame-rate in ultrasound imaging. For cardiac applications, the visualization of fine structures and the ability to track their motion is equally impo ... Full text Link to item Cite

Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software.

Journal Article J Am Soc Echocardiogr · June 2018 BACKGROUND: Right ventricular peak systolic longitudinal strain (RVLS) has emerged as an approach for quantifying right ventricular function in diseases such as pulmonary hypertension and congenital heart disease. A major limitation in applying RVLS is tha ... Full text Link to item Cite

Two-dimensional global longitudinal strain is superior to left ventricular ejection fraction in prediction of outcome in patients with left-sided infective endocarditis.

Journal Article Int J Cardiol · June 1, 2018 BACKGROUND: Impaired cardiac function is the main predictor of poor outcome in infective endocarditis (IE). Global longitudinal strain (GLS) derived from two-dimensional strain echocardiography has proven superior in prediction of long-term outcome as comp ... Full text Link to item Cite

Impaired Recovery of Left Ventricular Function in Patients With Cardiomyopathy and Left Bundle Branch Block.

Journal Article J Am Coll Cardiol · January 23, 2018 BACKGROUND: Patients with left bundle branch block (LBBB) often respond to cardiac resynchronization therapy (CRT) with left ventricular ejection fraction (LVEF) improvement. Guideline-directed medical therapy (GDMT), not CRT, is first-line therapy for pat ... Full text Link to item Cite

Appropriate use of echocardiography and relation to clinical decision making in both inpatients and outpatients in a developing country.

Journal Article Echocardiography · January 2018 BACKGROUND: Use of echocardiography (echo) has exponentially increased in recent decades. Concerned about this scientific society developed appropriate use criteria (AUC). Clinical management still suffers geographical variations, and no objective data are ... Full text Link to item Cite

The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block.

Journal Article J Electrocardiol · 2018 Cardiac resynchronization therapy (CRT) has revolutionized the care of patients with heart failure with reduced ejection fraction (HFrEF) and left bundle branch block (LBBB); some hypothesize that electrical resynchronization may also benefit patients with ... Full text Link to item Cite

Strain in Complex Congenital Heart Disease in Infants and Children

Chapter · January 1, 2018 Varying degrees of heart failure is common in infants with complex single ventricular heart disease. Sometimes the heart failure is progressive without a clear etiology and unresponsive to intense pharmacotherapy creating a critical management dilemma. The ... Full text Cite

Cardiac Masses

Chapter · January 1, 2018 Echocardiography is the most common method for the detection of cardiac masses. Masses can be described as intracavitary (within chambers or great vessels, and attached to chamber walls, valves or great vessels) or intramural (located within the muscular s ... Full text Cite

Infective Endocarditis

Chapter · January 1, 2018 Infective endocarditis (IE) is an infection of the endocardial lining of the heart, the heart valves, intracardiac devices or prosthetic valves. The infection is mainly localized on the valvular structures, generally on the flow side of the valves or at lo ... Full text Cite

Mitral Valve Disease

Chapter · January 1, 2018 The mitral valve is the most easily recognized moving structure in the heart. Because of its rapid back and forth motion, the mitral valve serves as “home base” for almost all echocardiographic examinations. When the transducer is directed posteriorly from ... Full text Cite

Preface

Book · January 1, 2018 Cite

Echocardiography, Second Edition

Book · January 1, 2018 This updated textbook provides an essential evidence-based approach to echocardiography and includes practical case-based instruction illustrating a wide variety of clinical scenarios in which echocardiography is a vital diagnostic option for physicians. I ... Full text Cite

Strain Basics and Global Longitudinal Strain

Chapter · January 1, 2018 Measurement of myocardial global longitudinal strain (GLS) is no longer a research tool. Rather, GLS is now used for risk assessment and management of patients with a wide variety of clinical disorders. GLS is clearly a useful supplement to routine quantit ... Full text Cite

Regional Strain: The Physiology of Dyssynchrony

Chapter · January 1, 2018 There are two major functional applications for speckle tracked strain used in the study of cardiac function: global and regional. This chapter is about regional functional strain assessment. The basics of ultrasound speckle tracking and strain are discuss ... Full text Cite

Comparison of Incidence of Left Ventricular Systolic Dysfunction Among Patients With Left Bundle Branch Block Versus Those With Normal QRS Duration.

Journal Article Am J Cardiol · December 1, 2017 We compared the incidence of left ventricular systolic dysfunction (LVSD) among patients with left bundle branch block (LBBB) to a matched cohort of patients with a narrow QRS duration <120 ms (NQRS). We hypothesized patients with preserved ejection fracti ... Full text Link to item Cite

The electromechanical substrate for response to cardiac resynchronization therapy in patients with right bundle branch block.

Journal Article Pacing Clin Electrophysiol · December 2017 BACKGROUND: Some patients with RBBB may respond to cardiac resynchronization therapy (CRT). However, little is known regarding the electromechanical substrate for CRT and whether this is the optimal pacing strategy. METHODS: This was a pilot prospective do ... Full text Link to item Cite

Notice of Removal: Spatio-temporal consistency of transthoracic ARFI-derived metrics of myocardial function

Conference IEEE International Ultrasonics Symposium, IUS · October 31, 2017 Cardiac function has traditionally been studied using pressure-volume (PV) loop analysis. PV loops can be used to derive functional indices such as end-systolic pressure volume relationship (ESPVR) - a measure of myocardial contractility, end-diastolic pre ... Full text Cite

A novel drift compensation algorithm for improved beat-to-beat repeatability of myocardial strain imaging: Preliminary in vivo results

Conference IEEE International Ultrasonics Symposium, IUS · October 31, 2017 Myocardial strain imaging has been shown to add significant prognostic and diagnostic value to echocardiography. While the reliability of ultrasound-based strain measurement techniques has improved considerably in terms of regional consistency and inter-re ... Full text Cite

Notice of Removal: A novel strain-based drift compensation algorithm for improved beat-to-beat repeatability of myocardial strain imaging: Preliminary in vivo results

Conference IEEE International Ultrasonics Symposium, IUS · October 31, 2017 Strain imaging is gaining traction as a means to assess cardiac function by tracking the cyclic deformation of the myocardium. Compared to traditional measures such as ejection fraction, global myocardial strain has been shown to be an earlier and more sen ... Full text Cite

Notice of Removal: High speed clinical Strain measurements

Conference IEEE International Ultrasonics Symposium, IUS · October 31, 2017 High speed ultrasound imaging is a new imaging method particularly applicable to cardiology. At Duke we have developed a real time high speed imaging system capable of producing up to 2500 images per second while maintaining the live imaging feature so ess ... Full text Cite

Notice of Removal: Clinical feasibility of a noninvasive method to interrogate myocardial function via strain and acoustic radiation force-derived stiffness

Conference IEEE International Ultrasonics Symposium, IUS · October 31, 2017 Myocardial elastance, derived from pressure-volume (PV) loops in the left ventricle (LV), can be used to assess LV function and myocardial performance. This method requires an invasive intracardiac pressure-volume catheter to be inserted in the LV, limitin ... Full text Cite

High-Frame-Rate Deformation Imaging in Two Dimensions Using Continuous Speckle-Feature Tracking.

Journal Article Ultrasound Med Biol · November 2016 The study describes a novel algorithm for deriving myocardial strain from an entire cardiac cycle using high-frame-rate ultrasound images. Validation of the tracking algorithm was conducted in vitro prior to the application to patient images. High-frame-ra ... Full text Link to item Cite

Frequent Activation Delay-Induced Mechanical Dyssynchrony and Dysfunction in the Systemic Right Ventricle.

Journal Article J Am Soc Echocardiogr · November 2016 BACKGROUND: Patients with systemic right ventricles frequently experience progressive heart failure and conduction abnormalities leading to abnormal ventricular activation. Activation delay-induced mechanical dyssynchrony can contribute to ventricular fail ... Full text Link to item Cite

Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunction.

Journal Article Eur Heart J · July 21, 2016 AIMS: We aimed to determine the frequency of aortic valve surgery (AVR) with or without coronary artery bypass grafting (CABG), among patients with moderate/severe aortic stenosis (AS) and left ventricular systolic dysfunction (LVSD), and its relationship ... Full text Link to item Cite

An Approach to Improve the Negative Predictive Value and Clinical Utility of Transthoracic Echocardiography in Suspected Native Valve Infective Endocarditis.

Journal Article J Am Soc Echocardiogr · April 2016 BACKGROUND: In patients with suspected native valve infective endocarditis, current guidelines recommend initial transthoracic echocardiography (TTE) followed by transesophageal echocardiography (TEE) if clinical suspicion remains. The guidelines do not ac ... Full text Link to item Cite

Patterns of Mechanical Inefficiency in Pediatric Dilated Cardiomyopathy and Their Relation to Left Ventricular Function and Clinical Outcomes.

Journal Article J Am Soc Echocardiogr · March 2016 BACKGROUND: Pediatric dilated cardiomyopathy (DCM) is associated with death or transplantation and is typically considered a homogeneous process affecting global left ventricular (LV) function. However, assessment of regional abnormalities that contribute ... Full text Link to item Cite

Implementing a Continuous Quality Improvement Program in a High-Volume Clinical Echocardiography Laboratory: Improving Care for Patients With Aortic Stenosis.

Journal Article Circ Cardiovasc Imaging · March 2016 BACKGROUND: The management of aortic stenosis rests on accurate echocardiographic diagnosis. Hence, it was chosen as a test case to examine the utility of continuous quality improvement (CQI) approaches to increase echocardiographic data accuracy and relia ... Full text Open Access Link to item Cite

Feature tracking algorithm for circumferential strain using high frame rate echocardiography

Conference Computing in Cardiology · March 1, 2016 This study aims to describe a feature tracking algorithm tailored to estimate circumferential strain on high frame rate ultrasound (HFR-US) images. The algorithm used the Hungarian assignment algorithm for tracking a basic feature descriptor. A second orde ... Cite

Left ventricular regional contraction abnormalities by echocardiographic speckle tracking in combined right bundle branch with left anterior fascicular block compared to left bundle branch block.

Journal Article J Electrocardiol · 2016 BACKGROUND: In contrast to LBBB patients less is known about patients with RBBB+LAFB regarding LV contractile abnormalities and the potential role of CRT. This study investigated whether patients with RBBB+LAFB morphology have echocardiographic mechanical ... Full text Link to item Cite

Reply: Echocardiographic Substrate for Biventricular Pacing.

Journal Article J Am Coll Cardiol · December 29, 2015 Full text Link to item Cite

In vivo transthoracic measurements of acoustic radiation force induced displacements in the heart over the cardiac cycle

Conference 2015 IEEE International Ultrasonics Symposium, IUS 2015 · November 13, 2015 Myocardial elasticity is an important indicator of cardiac function and is affected in many disorders associated with heart failure. Ultrasound based interrogation of cardiac stiffness has been extensively studied in ex-vivo, open chest and intracardiac im ... Full text Cite

Live high-frame-rate echocardiography.

Journal Article IEEE Trans Ultrason Ferroelectr Freq Control · October 2015 We describe an advanced real-time high-speed echocardiographic system with live display while scanning. Images are acquired at rates up to 1000 per second for adult cardiac applications and are stored in computer memory. Images may be played back in slow m ... Full text Link to item Cite

Temporal Trends in Disease Severity and Predicted Surgical Risk at the Time of Referral for Echocardiography in Patients Diagnosed with Aortic Stenosis.

Journal Article Crit Pathw Cardiol · September 2015 BACKGROUND: Calcific aortic stenosis (AS) is the most common underlying pathology in patients undergoing heart valve surgery, with an expected increasing prevalence among the aging population. METHODS AND RESULTS: We identified the temporal trends in refer ... Full text Link to item Cite

Identification of Typical Left Bundle Branch Block Contraction by Strain Echocardiography Is Additive to Electrocardiography in Prediction of Long-Term Outcome After Cardiac Resynchronization Therapy.

Journal Article J Am Coll Cardiol · August 11, 2015 BACKGROUND: Current guidelines suggest that patients with left bundle branch block (LBBB) be treated with cardiac resynchronization therapy (CRT); however, one-third do not have a significant activation delay, which can result in nonresponse. By identifyin ... Full text Link to item Cite

The influence of angle of insonation and target depth on speckle-tracking strain.

Journal Article J Am Soc Echocardiogr · May 2015 BACKGROUND: Speckle-tracking strain is almost universally cited as being independent of angle of insonation, but there are minimal confirmatory studies, and this claim may not be consistent with the known limitations of ultrasound axial and lateral spatial ... Full text Link to item Cite

Predictors and progression of aortic stenosis in patients with preserved left ventricular ejection fraction.

Journal Article Am J Cardiol · January 1, 2015 We aimed to characterize the hemodynamic progression of aortic stenosis (AS) in a contemporary unselected cohort of patients with preserved left ventricular ejection fraction. Current guidelines recommend echocardiographic surveillance of hemodynamic progr ... Full text Link to item Cite

Immediate mechanical effects of acute left bundle branch block by speckle tracked strain.

Journal Article J Electrocardiol · 2015 INTRODUCTION: Left bundle branch block (LBBB) is a known complication of transcatheter aortic valve replacement (TAVR) and has been shown to predict worsened outcomes in TAVR patients. A regional longitudinal strain pattern, termed the "classic" pattern of ... Full text Link to item Cite

Influence of QRS infarct score and QRS duration prior to transcatheter aortic valve replacement on follow-up left ventricular end systolic volume in patients with new persistent left bundle branch block.

Journal Article J Electrocardiol · 2015 BACKGROUND: New-onset left bundle branch block (LBBB) is a known complication during Transcatheter Aortic Valve Replacement (TAVR). This study evaluated the influence of pre-TAVR cardiac conditions on left ventricular functions in patients with new persist ... Full text Link to item Cite

Three-dimensional echocardiography: Lessons in overcoming time and space

Journal Article · January 1, 2015 A more intelligible display of complex cardiac pathology and the need for more accurate left ventricular (LV) function assessment prompted investigators to develop three-dimensional (3D) echocardiography immediately after the introduction of two-dimensiona ... Full text Cite

Blood flow visualization with real time high speed ultrasound

Conference IEEE International Ultrasonics Symposium, IUS · October 20, 2014 A new method of acquiring and displaying high speed ultrasound images has been developed. To extract flow information from the low intensity reflections of moving blood in these high frame rate images, difference imaging was found to be a particularly appl ... Full text Cite

Classic-pattern dyssynchrony and electrical activation delays in pediatric dilated cardiomyopathy.

Journal Article J Am Soc Echocardiogr · September 2014 BACKGROUND: Progressive heart failure leading to transplantation or death is common in pediatric dilated cardiomyopathy (DCM), and treatment options are limited. Select children with DCM have improved after cardiac resynchronization therapy (CRT), but pred ... Full text Link to item Cite

Comprehensive assessment of right ventricular function in patients with pulmonary hypertension with global longitudinal peak systolic strain derived from multiple right ventricular views.

Journal Article J Am Soc Echocardiogr · June 2014 BACKGROUND: Right ventricular (RV) function is a strong predictor of mortality in pulmonary hypertension (PH), but two-dimensional (2D) echocardiography-derived assessments of RV function that could aid in risk assessment and management of patients with PH ... Full text Link to item Cite

Right ventricular mechanics using a novel comprehensive three-view echocardiographic strain analysis in a normal population.

Journal Article J Am Soc Echocardiogr · April 2014 BACKGROUND: Although quantitative right ventricular (RV) strain analysis may be useful in congenital and acquired heart disease populations with RV failure, a comprehensive, standardized approach is lacking. An 18-segment RV strain analysis obtained from t ... Full text Link to item Cite

Dynamic indices of mitral valve function using perioperative three-dimensional transesophageal echocardiography.

Journal Article J Cardiothorac Vasc Anesth · February 2014 OBJECTIVE: Perioperative transesophageal echocardiography is essential for decision-making for mitral valve surgery. While two-dimensional transesophageal echocardiography represents the standard of care, tracking of dynamic changes using three-dimensional ... Full text Link to item Cite

Dyssynchrony: a different kind of mitral regurgitation.

Journal Article J Cardiothorac Vasc Anesth · December 2013 Full text Link to item Cite

Comparison of dyssynchrony parameters for VV-optimization in CRT patients.

Journal Article Pacing Clin Electrophysiol · November 2013 BACKGROUND: Optimization of the interventricular delay (VV-optimization) in cardiac resynchronization therapy (CRT) patients can be performed by evaluation of mechanical dyssynchrony. However, there is no consensus on which method to use. In this study, th ... Full text Link to item Cite

Short-lag spatial coherence imaging of cardiac ultrasound data: initial clinical results.

Journal Article Ultrasound Med Biol · October 2013 Short-lag spatial coherence (SLSC) imaging is a novel beamforming technique that reduces acoustic clutter in ultrasound images. A clinical study was conducted to investigate clutter reduction and endocardial border detection in cardiac SLSC images. Individ ... Full text Link to item Cite

Left bundle-branch block: the relationship between electrocardiogram electrical activation and echocardiography mechanical contraction.

Journal Article Am Heart J · August 2013 BACKGROUND: The relationship between myocardial electrical activation by electrocardiogram (ECG) and mechanical contraction by echocardiography in left bundle-branch block (LBBB) has never been clearly demonstrated. New strict criteria for LBBB based on a ... Full text Link to item Cite

Early echocardiographic deformation analysis for the prediction of sudden cardiac death and life-threatening arrhythmias after myocardial infarction.

Journal Article JACC Cardiovasc Imaging · August 2013 OBJECTIVES: This study sought to hypothesize that global longitudinal strain (GLS) as a measure of infarct size, and mechanical dispersion (MD) as a measure of myocardial deformation heterogeneity, would be of incremental importance for the prediction of s ... Full text Link to item Cite

Mechanical dyssynchrony evaluated by tissue Doppler cross-correlation analysis is associated with long-term survival in patients after cardiac resynchronization therapy.

Journal Article Eur Heart J · January 2013 AIMS: Pre-implant assessment of longitudinal mechanical dyssynchrony using cross-correlation analysis (XCA) was tested for association with long-term survival and compared with other tissue Doppler imaging (TDI)-derived indices. METHODS AND RESULTS: In 131 ... Full text Link to item Cite

Variability of global left ventricular deformation analysis using vendor dependent and independent two-dimensional speckle-tracking software in adults.

Journal Article J Am Soc Echocardiogr · November 2012 BACKGROUND: Evaluation of myocardial deformation by two-dimensional speckle-tracking is useful for clinical and research purposes. However, differences may exist among different ultrasound machines, software packages, frame rates, and observers. METHODS: T ... Full text Link to item Cite

Simple regional strain pattern analysis to predict response to cardiac resynchronization therapy: rationale, initial results, and advantages.

Journal Article Am Heart J · April 2012 BACKGROUND: A classical strain pattern of early contraction in one wall and prestretching of the opposing wall followed by late contraction has previously been associated with left bundle branch block (LBBB) activation and short-term response to cardiac re ... Full text Link to item Cite

Anatomic and clinical correlates of septal morphology in hypertrophic cardiomyopathy.

Journal Article Eur J Echocardiogr · February 2011 UNLABELLED: Aim The presence of septal hypertrophy in hypertrophic cardiomyopathy (HCM) is common. To date, there has been no accepted classification of septal morphology in HCM. Furthermore, the possible relationship between septal morphology and clinical ... Full text Link to item Cite

Mitral valve disease

Chapter · December 1, 2009 The mitral valve is the most easily recognized moving structure in the heart. Because of its rapid to and fro motion, the mitral valve serves as home base for almost all echocardiographic examinations. When the transducer is directed posteriorly from the c ... Full text Cite

Intracardiac masses

Journal Article · December 1, 2009 Masses within the heart are most commonly due to thrombus formation or vegetations associated with endocarditis. Two-dimensional echocardiography is much better than M-mode for the detection and localization of any intracardiac mass. Thrombus formation is ... Full text Cite

Echocardiography

Journal Article Echocardiography · December 1, 2009 Echocardiography has expanded greatly to become a sub-specialty in cardiology in its own right. From the original M-mode modality of 50 years ago, it has evolved into a complex multimodality method for evaluating and quantifying cardiovascular lesions. In ... Full text Cite

Color Doppler imaging of cardiac catheters using vibrating motors.

Journal Article Ultrason Imaging · October 2008 A miniature motor rotating at 11,000 rpm was attached onto the proximal end of cardiac electrophysiological (EP) catheters in order to produce vibrations at the tip that were then visualized by color Doppler on ultrasound scanners. The catheter tip was ima ... Full text Link to item Cite

Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularization.

Journal Article Am J Cardiol · May 15, 2004 In 107 patients with coronary disease and severe left ventricular dysfunction, we examined the prognostic power of viability identified by dobutamine stress echocardiography. At a mean follow-up of 27 months, patients with viable myocardium who underwent r ... Full text Link to item Cite

Feasibility of point-of-care echocardiography by internal medicine house staff.

Journal Article Am Heart J · March 2004 OBJECTIVE: To determine whether internal medicine house staff with limited training in echocardiography can use point-of-care echocardiography to make simple, clinically important diagnoses. BACKGROUND: Availability of small, portable ultrasound devices co ... Full text Link to item Cite

Prognostic usefulness of left ventricular thrombus by echocardiography in dilated cardiomyopathy in predicting stroke, transient ischemic attack, and death.

Journal Article Am J Cardiol · February 15, 2004 Echocardiograms of 290 patients with dilated cardiomyopathy (ejection fraction < or =35%) were reviewed for the presence of left ventricular (LV) apical abnormalities; outcomes of stroke and death were then correlated with the presence of LV thrombus. Duri ... Full text Link to item Cite

Neointimal hyperplasia rapidly reaches steady state in a novel murine vein graft model.

Journal Article J Vasc Surg · October 2002 OBJECTIVE: Neointimal hyperplasia remains a principal cause of vein graft failure. Genetic contributions to vein graft neointimal hyperplasia could be well studied in the mouse; however, surgical approaches to vein bypass surgery in the mouse have yet to r ... Link to item Cite

Real-time, volumetric echocardiography: usefulness of volumetric scanning for the assessment of cardiac volume and function.

Journal Article J Cardiol · 2001 BACKGROUND: A novel imaging system has been introduced which uses a dedicated two-dimensional echo probe for rapid beam forming to scan a pyramidal volume in real time. Real-time volumetric echocardiography has the potential to determine accurate cardiovas ... Link to item Cite

Real-time volumetric echocardiography: the technology and the possibilities.

Journal Article Echocardiography · November 2000 The heart is a dynamic organ with complexities in its shape. As such, it places special demands on three-dimensional techniques for reconstruction. Real-time volumetric echocardiography, which is based on phased array and parallel processing principles to ... Full text Link to item Cite

Clinical information determines the impact of transesophageal echocardiography on the diagnosis of infective endocarditis by the duke criteria.

Journal Article Am Heart J · June 2000 BACKGROUND: Although transesophageal echocardiography (TEE) is more sensitive than transthoracic echocardiography (TTE) in detecting echocardiographic evidence of infective endocarditis (IE), the impact of TEE on the clinical diagnosis of IE has not been c ... Full text Link to item Cite

Fenfluramine and phentermine and cardiovascular findings: effect of treatment duration on prevalence of valve abnormalities.

Journal Article Circulation · May 2, 2000 BACKGROUND: The combination of fenfluramine and phentermine was a widely used obesity treatment before the withdrawal of fenfluramine for an association with heart valve regurgitation. The prevalence and clinical significance of regurgitation among patient ... Full text Link to item Cite

Real-time 3-dimensional echocardiography evaluation of congenital heart disease.

Journal Article J Am Soc Echocardiogr · March 2000 We evaluated the ability of real-time 3-dimensional (RT3D) echocardiography to diagnose congenital heart defects and its potential for presenting structural abnormalities in novel views. Seventy-five patients with suspected congenital heart defects were ex ... Full text Link to item Cite

Means for load variation during echocardiographic assessment of the Frank-Starling relationship.

Journal Article J Am Soc Echocardiogr · October 1999 Because minimally invasive methods of preload variation are not validated for load-insensitive indexes of cardiac performance, intravenous nitroglycerin (NTG), phenylephrine, and saline solution (VOL) boluses were used in blocked and intact autonomic state ... Full text Link to item Cite

Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation.

Journal Article Am J Cardiol · June 17, 1999 More than 40 different beta-cardiac myosin heavy chain (beta-MHC) missense mutations have been identified that cause familial hypertrophic cardiomyopathy (FHC). Some of these are recognized to have important clinical manifestations, such as an increased in ... Full text Link to item Cite

Real-time, three-dimensional echocardiography: feasibility of dynamic right ventricular volume measurement with saline contrast.

Journal Article Am Heart J · May 1999 BACKGROUND: The asymmetry and complex shape of the right ventricle have made it difficult to determine right ventricular (RV) volume with 2-dimensional echocardiography. Three-dimensional cardiac imaging improves visualization of cardiac anatomy but is als ... Full text Link to item Cite

Assessment of regional wall motion abnormalities with real-time 3-dimensional echocardiography.

Journal Article J Am Soc Echocardiogr · January 1999 Accurate characterization of regional wall motion abnormalities requires a thorough evaluation of the entire left ventricle (LV). Although 2-dimensional echocardiography is frequently used for this purpose, the inability of tomographic techniques to record ... Full text Link to item Cite

Reconsidering quality.

Journal Article Heart · November 1998 Full text Link to item Cite

Real-time three-dimensional echocardiography for determining right ventricular stroke volume in an animal model of chronic right ventricular volume overload.

Journal Article Circulation · May 19, 1998 BACKGROUND: The lack of a suitable noninvasive method for assessing right ventricular (RV) volume and function has been a major deficiency of two-dimensional (2D) echocardiography. The aim of our animal study was to test a new real-time three-dimensional ( ... Full text Link to item Cite

Real-time 3D ultrasound: A new look at the heart

Journal Article Journal of Cardiovascular Diagnosis and Procedures · January 1, 1998 Matrix array ultrasound is a medical imaging modality in which a 3D volume is scanned electronically without physically moving the transducer, permitting rapid continuous 3D scanning of the heart. Unlike reconstructive 3D ultrasound, which relies on physic ... Cite

Active contour based on the elliptical Fourier series, applied to matrix-array ultrasound of the heart

Conference Proceedings of SPIE - The International Society for Optical Engineering · December 1, 1997 We describe an active contour based on the elliptical Fourier series, and its application to matrix-array ultrasound. Matrix-array ultrasound is a new medical imaging modality that scans a 3D-volume electronically without physically moving the transducer, ... Full text Cite

Reproducibility and beat-to-beat variability of digital echocardiograms

Journal Article Journal of the American Society of Echocardiography · December 1, 1997 To test the hypothesis that digital echocardiography (DE) is a reliable substitute for video tape (VT) for the interpretation of routine studies, we examined 51 pts with known or suspected cardiac disease. Images of the 4 standard views with and without co ... Cite

A letter from America.

Journal Article Heart · August 1997 Full text Link to item Cite

Contrast echocardiography: influence of ultrasonic machine settings, mixing conditions, and pressurization on pixel intensity and microsphere size of Albunex solutions in vitro.

Journal Article J Am Soc Echocardiogr · 1997 To use Albunex as a blood-flow tracer, the stability and consistency of microspheres under mixing conditions must be known. This study examined the effects of mixing conditions and machine settings on the size and echogenicity of Albunex solutions in vitro ... Full text Link to item Cite

Influences of ultrasonic machine settings, transducer frequency and placement of region of interest on the measurement of integrated backscatter and cyclic variation.

Journal Article Ultrasound Med Biol · 1997 Integrated backscatter and its cyclic variation are potentially important parameters to discriminate normal from diseased myocardium. Cyclic variation of integrated backscatter is expected to be independent of machine settings. Backscatter images of swine ... Full text Link to item Cite

Evaluation of the effect of transthoracic cardioversion from ventricular tachycardia to sinus rhythm on left atrial mechanical function.

Journal Article Am J Cardiol · December 15, 1996 We measured left atrial function during sinus rhythm before and after ventricular tachycardia was induced in an electrophysiology laboratory, using peak transmitral A-wave velocity from pulsed-Doppler transthoracic echocardiography as a marker of left atri ... Full text Link to item Cite

A letter from America.

Journal Article Heart · June 1996 Full text Link to item Cite

Negative predictive value of the Duke criteria for infective endocarditis.

Journal Article Am J Cardiol · February 15, 1996 With use of new Duke criteria, 405 episodes of suspected endocarditis were previously classified as "definite," "possible," or "rejected" endocarditis. To determine the negative predictive value of the Duke clinical criteria for the classification of suspe ... Full text Link to item Cite

Assessment of the Frank-Starling relationship by two-dimensional echocardiography.

Journal Article J Am Soc Echocardiogr · 1996 The Frank-Starling relationship between left ventricular stroke work and end-diastolic minor-axis cross-sectional area was evaluated as a load-insensitive measure of inotropic state by two-dimensional echocardiography in 10 conscious dogs. Stroke work was ... Full text Link to item Cite

Intraoperative echocardiography during congenital heart operations: experience from 1,000 cases.

Journal Article Ann Thorac Surg · December 1995 BACKGROUND: This article provides an overview of the application of intraoperative echocardiography during repair of congenital heart defects based on our experience with 1,000 patients. METHODS: The patients in this study all underwent repair of a congeni ... Full text Link to item Cite

Hypotension during dobutamine stress echocardiography: is it related to dynamic intraventricular obstruction?

Journal Article Am Heart J · August 1995 Although it has been shown that a hypotensive response during dobutamine stress echocardiography is not a marker of coronary artery disease, the mechanism of this response remains unclear. We hypothesize that hypotension during dobutamine stress echocardio ... Full text Link to item Cite

Does hypotension during dobutamine stress echocardiography correlate with anatomic or functional cardiac impairment?

Journal Article Am Heart J · June 1995 The development of hypotension during various exercise stress tests has been correlated with the presence of multivessel coronary artery disease and impaired left ventricular contractility. Hypotension may also occur during dobutamine stress echocardiograp ... Full text Link to item Cite

To my friend in echocardiography.

Journal Article Br Heart J · May 1995 Full text Link to item Cite

Transesophageal echocardiographic assessment of reversal of systolic pulmonary venous flow in mitral stenosis.

Journal Article Am J Cardiol · January 1, 1995 Transesophageal echocardiography and diagnostic cardiac catheterization were performed in 36 patients with symptomatic mitral stenosis to assess the incidence and significance of systolic flow reversal in the pulmonary veins. Mitral regurgitation was grade ... Full text Link to item Cite

Three-dimensional flow images by reconstruction from two-dimensional vector velocity maps.

Journal Article J Am Soc Echocardiogr · 1995 A method for constructing three-dimensional images of flow is described. The technique involves the acquisition of numerous closely spaced planes, each comprised of a map of the two-dimensional velocities measured in that plane. Each such vector velocity m ... Full text Link to item Cite

Preamble

Journal Article Journal of the American Society of Echocardiography · January 1, 1995 Full text Cite

Effect of dobutamine stress echocardiography on mitral regurgitation.

Journal Article J Am Coll Cardiol · January 1995 OBJECTIVES: This study was performed to examine the effect of dobutamine stress echocardiography on mitral regurgitation and to test the hypothesis that mitral regurgitation will increase in patients with an ischemic response. BACKGROUND: New or worsening ... Full text Link to item Cite

Value of transthoracic echocardiography in predicting embolic events in active infective endocarditis. Duke Endocarditis Service.

Journal Article Am J Cardiol · October 15, 1994 The purpose of this study was twofold: (1) to determine interobserver variability of echocardiographic characteristics of vegetations in patients with infective endocarditis, and (2) to assess the value of these vegetation characteristics in predicting emb ... Full text Link to item Cite

Improved cardiac anthropomorphic phantom.

Journal Article J Ultrasound Med · August 1994 An improved cardiac sonographic phantom is described that simulates the anatomy of the human heart for applications as a low cost quality assurance and training tool in echocardiography. The major new feature in the phantom is the development of a polyuret ... Full text Link to item Cite

A letter from America.

Journal Article Br Heart J · April 1994 Full text Link to item Cite

New criteria for diagnosis of infective endocarditis: utilization of specific echocardiographic findings. Duke Endocarditis Service.

Journal Article Am J Med · March 1994 PURPOSE: This study was designed to develop improved criteria for the diagnosis of infective endocarditis and to compare these criteria with currently accepted criteria in a large series of cases. PATIENTS AND METHODS: A total of 405 consecutive cases of s ... Full text Link to item Cite

Measurement of left ventricular volume in normal and volume-overloaded canine hearts.

Journal Article Am J Physiol · January 1994 Serial studies of adaptation to aortic regurgitation (AR) were undertaken to determine whether sonomicrometry and echocardiography could be combined to measure changes in left ventricular (LV) cavitary volume (Vlv) and wall mass using the geometric formula ... Full text Link to item Cite

A letter from America

Journal Article British Heart Journal · 1994 Cite

Usefulness of dobutamine echocardiography for detecting restenosis after percutaneous transluminal coronary angioplasty.

Journal Article Am J Cardiol · December 1, 1993 To determine the usefulness of dobutamine stress echocardiography for detecting restenosis after percutaneous transluminal coronary angioplasty, the results of coronary arteriography and dobutamine stress echocardiography were compared in 103 patients 6 mo ... Full text Link to item Cite

Opacification and border delineation improvement in patients with suboptimal endocardial border definition in routine echocardiography: results of the Phase III Albunex Multicenter Trial.

Journal Article J Am Coll Cardiol · November 1, 1993 OBJECTIVES: This study was designed to assess the safety and efficacy of intravenously administered sonicated human serum albumin for enhancing echocardiographic delineation of the left ventricular endocardium and improving assessment of wall motion in pat ... Full text Link to item Cite

Etiology of large pericardial effusions.

Journal Article Am J Med · August 1993 PURPOSE: To determine the effectiveness of the preoperative evaluation and overall diagnostic efficacy of subxiphoid pericardial biopsy with fluid drainage in patients with new, large pericardial effusions. DESIGN: A prospective interventional case series ... Full text Link to item Cite

Correlation of adenosine echocardiography and thallium scintigraphy.

Journal Article Am Heart J · June 1993 Echocardiography and thallium-201 imaging with coronary vasodilators such as dipyridamole have been shown to be useful in detecting the presence and prognostic significance of coronary artery disease. Adenosine, a potent and direct coronary vasodilator, ha ... Full text Link to item Cite

Echocardiography in the diagnosis of thoracic aortic pathology.

Journal Article Int J Card Imaging · 1993 Transthoracic two-dimensional and Doppler echocardiography has been well established as a useful technique for evaluating many pathologic processes affecting the thoracic aorta. However, the distance of the aortic arch and descending thoracic aorta from th ... Full text Link to item Cite

The learning curve for intraoperative echocardiography during congenital heart surgery.

Journal Article Ann Thorac Surg · October 1992 Our group has previously reported a large prospective experience with the use of intraoperative echocardiography with Doppler color-flow imaging (IE-DCFI) during the repair of congenital heart defects. We have now performed IE-DCFI in 621 patients and have ... Full text Link to item Cite

Diagnosis and management (by subxiphoid pericardiotomy) of large pericardial effusions causing cardiac tamponade.

Journal Article Am J Cardiol · April 15, 1992 To determine the clinical features, course and outcome of patients with cardiac tamponade, 57 consecutive patients with new, large pericardial effusions were prospectively studied. Twenty-five patients (44%) developed cardiac tamponade with venous hyperten ... Full text Link to item Cite

Subxiphoid pericardiotomy in the diagnosis and management of large pericardial effusions associated with malignancy.

Journal Article Chest · April 1992 To determine the safety, diagnostic value, and clinical outcome of patients with malignancy undergoing subxiphoid pericardiotomy for large pericardial effusions, we prospectively studied 25 consecutive patients with malignancy and new, large pericardial ef ... Full text Link to item Cite

Health Care Financing Administration release of final physician payment reform regulation.

Journal Article J Am Soc Echocardiogr · 1992 The Health Care Financing Administration has released final regulations concerning physician payment reform. The new method will significantly affect global, technical, and professional reimbursement. The American Society of Echocardiography is preparing r ... Full text Link to item Cite

Anthropomorphic cardiac ultrasound phantom with coronary arteries

Journal Article Proceedings of the Annual Conference on Engineering in Medicine and Biology · December 1, 1991 The cardiac anthropomorphic ultrasound phantom is improved by the addition of two new features. An aorta with a bifurcation is molded into the torso via a 'lost wax' procedure. B-scan images of contrast medium and color-flow Doppler images show flow patter ... Cite

Safety and efficacy of sonicated albumin microspheres in perfusion and vein graft patency assessments.

Journal Article Clin Cardiol · November 1991 This study was designed to identify a concentration of sonicated albumin microspheres that is safe, useful in determining graft patency, and provides an estimate of regional myocardial perfusion. The study included 8 patients between 50 and 72 years of age ... Full text Link to item Cite

Intraoperative transesophageal Doppler color flow imaging used to guide patient selection and operative treatment of ischemic mitral regurgitation.

Journal Article Circulation · August 1991 BACKGROUND: Intraoperative transesophageal Doppler color flow imaging (TDCF) affords the opportunity to assess mitral valve competency immediately before and after cardiopulmonary bypass (CPB). The purpose of this study was to assess the utility of TDCF to ... Full text Link to item Cite

Report of the Council on Scientific Affairs: ultrasonic imaging of the heart: report of the Ultrasonography Task Force.

Journal Article Arch Intern Med · July 1991 The use of ultrasonography in cardiology has progressed so dramatically that not only is anatomic information available but information can also be derived about cardiac hemodynamics. Applications range from intravascular ultrasonic imaging of coronary ath ... Link to item Cite

Comparison of intravascular ultrasound, external ultrasound and digital angiography for evaluation of peripheral artery dimensions and morphology.

Journal Article Am J Cardiol · April 15, 1991 Validation of catheter-based intravascular ultrasound imaging has been based on comparisons with histology and digital angiography, each of which may have limitations in the assessment of arterial size and morphology. External, high-frequency ultrasound ca ... Full text Link to item Cite

Pericardial effusion after intravenous recombinant tissue-type plasminogen activator for acute myocardial infarction.

Journal Article Am J Cardiol · March 1, 1991 The effect of thrombolytic therapy on the frequency, time course and sequelae of pericardial effusion after myocardial infarction are unknown. A prospective, serial, 2-dimensional echocardiographic study of patients with myocardial infarction who received ... Full text Link to item Cite

Echo-Doppler in the diagnosis and management of congenital heart disease.

Journal Article Trends Cardiovasc Med · March 1991 Advancements in echo-Doppler technology now provide the capability for both high-quality anatomic imaging as well as the assessment of cardiac flows and hemodynamics. Given these capabilities, and the potentially complex nature of all congenital heart lesi ... Full text Link to item Cite

The utility of echocardiography in the diagnostic strategy of postinfarction ventricular septal rupture: a comparison of two-dimensional echocardiography versus Doppler color flow imaging.

Journal Article Am Heart J · January 1991 The diagnostic accuracy of Doppler color flow imaging in the diagnosis of postinfarction ventricular septal defects has not been established. In this study, 43 patients with unexplained hypotension or a new murmur in the periinfarct period were evaluated w ... Full text Link to item Cite

Real-time, three-dimensional echocardiography: feasibility and initial use.

Journal Article Echocardiography · January 1991 The purpose of this article is to review new approaches to three-dimensional acquisition and presentation of echocardiographic data. New three-dimensional phased-array devices hold great promise for the development and application of new descriptors for le ... Full text Link to item Cite

Reporting of preliminary data: time to take our sonographers "off the hook".

Journal Article J Am Soc Echocardiogr · 1991 The article by McDonald et al. points out the widespread demand for preliminary reporting of echocardiographic data by sonographers, at least in the setting of physicians in training. Such preliminary reporting is illegal in most states because it constitu ... Full text Link to item Cite

Routine use of intraoperative epicardial echocardiography and Doppler color flow imaging to guide and evaluate repair of congenital heart lesions. A prospective study.

Journal Article J Thorac Cardiovasc Surg · August 1990 Routine epicardial two-dimensional echocardiography, Doppler, and Doppler color flow imaging studies were performed before and after cardiopulmonary bypass in 328 patients undergoing operations for congenital heart disease. Ages ranged from 1 day to 59 yea ... Link to item Cite

In vitro analysis of jets by Doppler colour flow imaging: the importance of time to maximum jet area.

Journal Article Eur Heart J · April 1990 Regurgitant jets were simulated in vitro and analysed using Doppler colour flow imaging. The regurgitant volumes were estimated using total jet area (JA), variance area (VA), and the maximum area of variance x time to maximum area of variance (MAVT). Both ... Full text Link to item Cite

Relation of quantitative coronary lesion measurements to the development of exercise-induced ischemia assessed by exercise echocardiography.

Journal Article J Am Coll Cardiol · April 1990 To assess the relation of quantitative measures of coronary stenoses to the development of exercise-induced regional wall motion abnormalities, 34 patients with isolated, single vessel coronary artery lesions and normal wall motion at rest underwent exerci ... Full text Link to item Cite

Intraoperative perfusion contrast echocardiography. Initial experience during coronary artery bypass grafting.

Journal Article J Thorac Cardiovasc Surg · March 1990 Intraoperative evaluation of the effectiveness of myocardial revascularization has been limited by an inability to assess regional myocardial perfusion. Microbubbles of sonicated diatrizoate sodium and diatrizoate meglumine (Renografin) have been an effect ... Link to item Cite

The utility of transesophageal echocardiography and Doppler color flow imaging in patients undergoing cardiac valve surgery.

Journal Article J Am Coll Cardiol · February 1990 To assess the value of intraoperative transesophageal echocardiography during cardiac valve surgery, 154 consecutive patients who had a valve operation in conjunction with pre- and postcardiopulmonary bypass transesophageal imaging were studied. Prebypass ... Full text Link to item Cite

Use of Doppler echocardiography and amyl nitrite inhalation to characterize left ventricular outflow obstruction in hypertrophic cardiomyopathy.

Journal Article Chest · February 1990 The presence of left ventricular outflow tract obstruction (LVOTO) of either a resting or dynamic nature may have important therapeutic and prognostic implications in patients with hypertrophic cardiomyopathy (HCM). Doppler echocardiograms combined with am ... Full text Link to item Cite

Reimbursement update: looking toward the 1990s.

Journal Article J Am Soc Echocardiogr · 1990 Some Medicare carriers have independently decided to treat all billings for echocardiographic services as radiologic, whereas others have decided to treat billings from multispecialty practices that include a radiologist as radiologic services. The result ... Full text Link to item Cite

The use of intraoperative echo with Doppler color flow imaging to predict outcome after repair of congenital cardiac defects.

Journal Article Ann Surg · October 1989 Surgical repair of congenital cardiac defects (CCD) has undergone a remarkable evolution in the past decade. Major defects are now often completely corrected in early infancy with continually improving rates of survival. It has become clear that the next m ... Full text Link to item Cite

Two-dimensional echocardiography in arrhythmogenic right ventricular dysplasia.

Journal Article Eur Heart J · September 1989 Comparison of two-dimensional echocardiography and right ventricular angiographic findings was carried out in patients with arrhythmogenic right ventricular dysplasia. Diagnosis was based on ECG and angiographic criteria in all cases. Echo and angiographic ... Full text Link to item Cite

Intraoperative prebypass and postbypass epicardial color flow imaging in the repair of atrioventricular septal defects.

Journal Article J Thorac Cardiovasc Surg · July 1989 The use of intraoperative epicardial Doppler echocardiography with color flow imaging both before and after cardiopulmonary bypass to assist repair of congenital heart defects in infants and small children has not been reported. To demonstrate its simplici ... Link to item Cite

Doppler left ventricular diastolic filling abnormalities in aortic stenosis and their relation to hemodynamic parameters.

Journal Article Am J Cardiol · June 1, 1989 Doppler mitral flow indexes and their relation to invasively measured hemodynamic diastolic indexes were assessed in 13 patients with isolated aortic stenosis (AS), and compared to Doppler indexes in 10 normal subjects matched for age, heart rate, left ven ... Full text Link to item Cite

Patent foramen ovale and decompression sickness in divers.

Journal Article Lancet · March 11, 1989 30 patients with a history of decompression sickness were examined for the presence of patent foramen ovale by bubble contrast, two-dimensional echocardiography and colour flow doppler imaging. With bubble contrast, 11 (37%) of the patients had right-to-le ... Full text Link to item Cite

Utility of Doppler color flow imaging for identification of femoral arterial complications of cardiac catheterization.

Journal Article Am Heart J · March 1989 Doppler color flow and two-dimensional ultrasonographic images of the femoral region were obtained in 25 patients referred for suspected vascular complications of cardiac catheterization. Five patients had normal findings, while 23 abnormalities were noted ... Full text Link to item Cite

Analysis of the early rise in aortic transvalvular gradient after aortic valvuloplasty.

Journal Article Am Heart J · February 1989 The relationship between dynamic changes in aortic valve gradient and left ventricular ejection performance in the early period after successful percutaneous aortic valvuloplasty has not been described in detail. Accordingly 20 adult patients with severe s ... Full text Link to item Cite

Imaging of the coronary arteries by transesophageal echocardiography.

Journal Article J Am Soc Echocardiogr · 1989 Detection of the proximal left and right coronary arteries is possible by transesophageal echocardiography with rather high frequencies. The proximal left coronary artery can be detected in 86% of patients and the proximal right in 82%. Precise identificat ... Full text Link to item Cite

Intraoperative echocardiography in congenital heart disease surgery: preliminary report on a current study.

Journal Article Am J Cardiol · 1989 CLINICAL PERSPECTIVE: The first prospective trial in which both echocardiography and Doppler color flow imaging (echo-DCFI) are used routinely during surgery for congenital heart lesions has been undertaken at Duke Medical Center. Precardiopulmonary bypass ... Link to item Cite

Changes in Medicare reimbursement for echocardiographic procedures.

Journal Article J Am Soc Echocardiogr · 1989 Medicare reimbursement for echocardiographic procedures is clouded by the fact that Medicare defines ultrasound services to be "radiologic." As such, a 40% limitation has been imposed in some states. In addition, as a result of the Omnibus Budget Reconcili ... Full text Link to item Cite

In vivo estimation of left ventricular wall volume in volume-overloaded canine hearts

Journal Article American Journal of Physiology - Heart and Circulatory Physiology · December 1, 1988 Several geometric algorithms have been applied to estimate left ventricular wall volume (V(wall)) from two-dimensional echocardiograms but have not been validated in eccentrically hypertrophied hearts. These algorithms can be fitted to the general formula: ... Cite

Crises in echocardiography.

Journal Article J Am Soc Echocardiogr · 1988 Full text Link to item Cite

Consequence of the Omnibus Budget Reconciliation Act of 1987: elimination of markup for certain diagnostic tests.

Journal Article J Am Soc Echocardiogr · 1988 The Omnibus Budget Reconciliation Act of 1987 has significantly changed the rules governing the way in which charges must be made to Medicare concerning certain tests, including ultrasound, by a physician who provides these tests by means of an outside sup ... Full text Link to item Cite

Interpretation of echocardiographic data: are physicians and sonographers violating the law?

Journal Article J Am Soc Echocardiogr · 1988 When a sonographer renders diagnostic interpretations from echocardiographic data, the possibility exists that state statutes concerning the unauthorized practice of medicine may be violated. Problems likely exist in this regard when the sonographer render ... Full text Link to item Cite

Sequence of mitral valve motion and transmitral blood flow during manual cardiopulmonary resuscitation in dogs.

Journal Article Circulation · August 1987 According to the thoracic pump model of cardiopulmonary resuscitation (CPR), the heart serves as a passive conduit for blood flow from the pulmonary to the systemic vasculature, necessitating an open mitral valve and anterograde transmitral blood flow duri ... Full text Link to item Cite

In vitro color flow, pulsed and continuous wave Doppler ultrasound masking of flow by prosthetic valves.

Journal Article J Am Coll Cardiol · June 1987 On the hypothesis that Doppler ultrasound fails to penetrate prosthetic valves, an in vitro flow simulation system was constructed in a large water tank. Conventional pulsed, continuous wave and Doppler color flow systems were used to detect flow in tubing ... Full text Link to item Cite

Intraoperative transesophageal color flow mapping: initial experience.

Journal Article Anesth Analg · May 1987 Transesophageal Doppler color flow mapping (TEDCFM) is a new ultrasound modality now being developed. It provides a convenient, noninvasive way to image cardiac anatomy and intracardiac blood flow that is applicable to intraoperative use. We describe its u ... Full text Link to item Cite

Validation of in vivo two-dimensional echocardiographic dimension measurements using myocardial mass estimates in dogs.

Journal Article Am Heart J · March 1987 The accuracy of in vivo measurements of left ventricular wall thickness and chamber size by means of two-dimensional echocardiography was investigated by comparing left ventricular mass estimates obtained at end diastole in 15 closed-chest dogs with a wide ... Full text Link to item Cite

Atrial septal aneurysm: association with cerebrovascular and peripheral embolic events.

Journal Article Stroke · 1987 Patient records in 36 consecutively identified patients with typical echocardiographic findings of atrial septal aneurysm were reviewed. Ten of the 36 (28%) had cerebrovascular events. Of these 10, 5 had completed strokes of definite embolic origin on the ... Full text Link to item Cite

Transesophageal Applications of Color Flow Imaging

Journal Article Echocardiography · January 1, 1987 Full text Cite

Real-time orthogonal mode scanning of the heart. I. System design.

Journal Article J Am Coll Cardiol · June 1986 A necessary percursor to real-time three-dimensional echocardiographic imaging is the ability to obtain multiple planes of acoustic data simultaneously. A new ultrasound imaging technique facilitates the display of two real-time orthogonal B-mode images (O ... Full text Link to item Cite

Utility of echocardiography in the management of patients with penetrating missile wounds of the heart.

Journal Article J Am Coll Cardiol · May 1986 Nine consecutive patients with penetrating missile wounds of the heart were evaluated by M-mode and two-dimensional echocardiography for localization of retained missile fragments noted to be moving in synchrony with the heart by fluoroscopy. Echocardiogra ... Full text Link to item Cite

Interatrial shunting in atrial septal aneurysm.

Journal Article Am J Cardiol · February 1, 1986 Adequate contrast 2-dimensional (2-D) echocardiograms were recorded in 13 to 16 patients with typical 2-D findings of atrial septal aneurysm. Five patients were referred for detection of intracardiac source of emboli after embolic stroke and 11 were evalua ... Full text Link to item Cite

Pseudoaneurysm of the Left Ventricle

Journal Article Echocardiography · January 1, 1986 Full text Cite

Subvalvular left ventricular pseudoaneurysm after mitral valve replacement: two-dimensional echocardiographic findings.

Journal Article J Am Coll Cardiol · November 1985 Disruption of the posterior mitral anulus is a rare complication of mitral valve replacement that may result in subvalvular left ventricular pseudoaneurysm formation. Such pseudoaneurysm formation was easily recognized by two-dimensional echocardiography i ... Full text Link to item Cite

Ultrasound diagnosis of pseudoaneurysm and contiguous ventricular septal defect complicating inferior myocardial infarction.

Journal Article J Am Coll Cardiol · November 1985 Two patients with recent inferior myocardial infarction were found by two-dimensional and Doppler echocardiography to have both an inferior wall pseudoaneurysm and a contiguous rupture of the posterior ventricular septum. The pseudoaneurysm was not suspect ... Full text Link to item Cite

Cardiac involvement in myotonic muscular dystrophy.

Journal Article Medicine (Baltimore) · November 1985 Cardiac illness in myotonic muscular dystrophy (MyD) is infrequent, but subclinical cardiac involvement in MyD is very common (found in 42 of 46 subjects) and may be responsible for sudden death. In this series, we found ECG abnormalities in 72%, left vent ... Full text Link to item Cite

A reconsideration of Doppler assessed gradients in suspected aortic stenosis.

Journal Article Am Heart J · October 1985 To further define the clinical role of continuous wave Doppler echocardiography for determining aortic valve gradient, we studied 60 consecutive adult patients (age range 22 to 81 years, mean age 63) with suspected aortic stenosis within 24 hours of cathet ... Full text Link to item Cite

Right ventricular isolation procedures for nonischemic ventricular tachycardia.

Journal Article J Thorac Cardiovasc Surg · August 1985 Nonischemic ventricular tachycardia most commonly arises in the right ventricular free wall and is frequently refractory to medical therapy. Many different types of surgical procedures have been employed to treat medically refractory nonischemic ventricula ... Link to item Cite

Comparison of two-dimensional echocardiographic and angiographic findings in arrhythmogenic right ventricular dysplasia.

Journal Article Am J Cardiol · June 1, 1985 Comparison of 2-dimensional (2-D) echocardiographic and right ventricular (RV) angiographic findings was performed in 10 patients with arrhythmogenic RV dysplasia. Diagnosis was based on accepted electrocardiographic and angiographic criteria. Nine patient ... Full text Link to item Cite

Real-time Doppler color flow mapping in stenotic valvular lesions

Journal Article Echocardiography · January 1, 1985 Two-dimensional real-time Doppler color flow mapping methods are early in their course of clinical use and further experience is obviously required to realize the full potential of this method for the evaluation of stenotic valvular lesions. Many new syste ... Cite

Pulsed Doppler spectral analysis of bounded fluid jets.

Journal Article Ultrasound Med Biol · 1984 To test the hypothesis that pulsed Doppler ultrasound spectral properties of bounded fluid jets related to orifice size, in vitro examinations were performed using a hydraulic simulator (standpipe, compliant receiving chamber, and variable round orifice). ... Full text Link to item Cite

The safety of contrast echocardiography: report of the Committee on Contrast Echocardiography for the American Society of Echocardiography.

Journal Article J Am Coll Cardiol · January 1984 The results of a survey of 363 physicians performing echocardiography were evaluated to assess the relative safety of contrast echocardiography. Fifteen physicians reported a variety of transient side effects, including neurologic and respiratory symptoms. ... Full text Link to item Cite

The cardiac diagnostic unit. A new approach to patient care.

Journal Article Radiol Clin North Am · December 1983 The Cardiac Diagnostic Unit at Duke University Hospital brings together multiple diagnostic services for evaluation of patients with cardiovascular disease. This Unit is a combined effort of the departments of Medicine, Radiology, Surgery, Bioengineering, ... Link to item Cite

Echocardiography in infective endocarditis.

Journal Article Herz · October 1983 Echocardiography may detect the presence of vegetative lesions in between 55 and 80% of patients with the clinical syndrome of bacterial endocarditis. While the mere presence of vegetations does not alone warrant surgical intervention in patients with this ... Link to item Cite

Optimal resources for ultrasonic examination of the heart. Echocardiography study group.

Journal Article Circulation · February 1982 This paper provides guidelines for the optimal, rather than minimal, performance of ultrasonic examination of the heart for current clinical applications using conventional echocardiographic equipment. Since the original report of this Inter-Society Commis ... Link to item Cite

CT of intracardiac tumor.

Journal Article AJR Am J Roentgenol · September 1981 Full text Link to item Cite

Extraction of intramyocardial foreign body utilizing operative ultrasonography.

Journal Article J Thorac Cardiovasc Surg · September 1981 Technical advances in cardiac surgery have made accessible previously remote regions within the heart and great vessels; nevertheless, limitations in the ability to locate intramyocardial foreign bodies with precision utilizing conventional radiographic te ... Link to item Cite

Contrast M-mode ultrasonography of the inferior vena cava.

Journal Article Circulation · May 1981 Contrast M-mode and two-dimensional ultrasonography of the inferior vena cava were performed in 65 patients with various acquired and congenital cardiac disorders. After saline was injected into a peripheral arm vein, the inferior vena cava was visualized ... Full text Link to item Cite

Combined doppler and phased-array echocardiographic estimation of cardiac output.

Journal Article Circulation · February 1981 The capability of a pulsed Doppler flowmeter combined with a phased-array imaging system to measure volume flow was tested in vitro and in patients undergoing cardiac catheterization. The Doppler-phased-array system (DPA) was used to determine vessel diame ... Full text Link to item Cite

Evaluation of the left ventricle with two dimensional echocardiography.

Journal Article Am J Cardiol · December 18, 1980 Two dimensional echocardiography, because of its wide field of view, has been shown to be superior to the M mode approach for ultrasonic evaluation of the left ventricle. The use of this technique for determination of ventricular volume estimates and detec ... Full text Link to item Cite

The diagnostic and prognostic significance of coronary artery calcification. A report of 800 cases.

Journal Article Radiology · December 1980 The significance of coronary artery calcification was assessed in 800 patients who underwent cardiac fluoroscopy and selective coronary cineangiography. Calcification was shown by fluoroscopy in 250, of whom 236 (94%) had greater than or equal to 75% steno ... Full text Link to item Cite

Two-dimensional echocardiography.

Journal Article Radiol Clin North Am · April 1980 Link to item Cite

Echocardiography of the mitral valve.

Journal Article Med Clin North Am · March 1980 Full text Link to item Cite

Echocardiographic documentation of vegetative lesions in infective endocarditis: clinical implications.

Journal Article Circulation · February 1980 Eighty-seven patients with the clinical syndrome of infective endocarditis were examined by M-mode and two-dimensional echocardiography. Patients were divided into two groups based on the presence or absence of echocardiographically detected vegetative les ... Full text Link to item Cite

Detection of persistent left superior vena cava by two-dimensional contrast echocardiography.

Journal Article J Clin Ultrasound · October 1979 One hundred seventy adult patients with possible congenital or valvular heart disease underwent contrast two-dimensional echocardiographic examination as part of a precatheterization evaluation. Persistent left superior vena cava was detected in 5 patients ... Full text Link to item Cite

Detection and exclusion of interatrial shunts by two-dimensional echocardiography and peripheral venous injection.

Journal Article Circulation · February 1979 Two-dimensional echocardiography (2-D echo) was used with peripherally injected contrast material to detect interatrial shunts in 33 patients. Group 1 consisted of 11 patients having classic clinical findings of atrial septal defect. Group 2 consisted of 1 ... Full text Link to item Cite

Phased array cardiac imaging: system operation, results and clinical role.

Journal Article Acta Med Scand Suppl · 1979 Proper clinical use of real-time, two-dimensional echocardiography depends upon three major factors: the clinical questions posed of these imaging devices, the interrelationship of this technique with other imaging techniques and the quality of the ultraso ... Full text Link to item Cite

Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements.

Journal Article Circulation · December 1978 Four hundred M-mode echocardiographic surveys were distributed to determine interobserver variability in M-mode echocardiographic measurements. This was done with a view toward examining the need and determining the criteria for standardization of measurem ... Full text Link to item Cite

The prognostic spectrum of left main stenosis.

Journal Article Circulation · May 1978 Three-year survival for 163 consecutive medically treated patients with 50% or greater left main stenosis was 50%. Survival was significantly higher for patients with 50 to 70% left main stenosis (one and three-year survivals of 91% and 66%) than for patie ... Full text Link to item Cite

Detection of tricuspid regurgitation with two-dimensional echocardiography and peripheral vein injections.

Journal Article Circulation · January 1978 "Contrast echocardiography", utilizing a two-dimensional ultrasound system and peripheral venous injections, was used for the detection of tricuspid regurgitation in 30 patients. The appearance of contrast in the inferior vena cava and the back and forth m ... Full text Link to item Cite

The role of the exercise test in the evaluation of patients for ischemic heart disease.

Journal Article Circulation · January 1978 A cohort of 1472 patients who underwent both exercise stress testing and coronary angiography within six weeks was examined. The data indicated that a combination of exercise parameters is both diagnostically and prognostically important. Almost all patien ... Full text Link to item Cite

Real time ultrasound tomography of the adult brain.

Journal Article Stroke · 1978 Initial clinical results are reported from a new real time, 2-dimensional ultrasound scanner modified for adult cephalic applications. An optimized transducer design and the use of the dynamically focused phased array imaging system have resulted in ultras ... Full text Link to item Cite

Two-dimensional echocardiographic findings in atrial septal defect.

Journal Article Circulation · September 1977 Two-dimensional echocardiographic findings in a group of 24 patients with atrial septal defects were correlated with findings obtained by cardiac catheterization and M-mode echocardiography. The prevalence of mitral prolapse was 95% by two-dimensional echo ... Full text Link to item Cite

Dynamic cardiac imaging using a focused, phased-array ultrasound system.

Journal Article Am J Med · July 1977 A two-dimensional ultrasound imaging system capable of producing high resolution, cross-sectional images of the heart in real-time has been developed. This system relies upon phased-array principles to rapidly steer and focus the ultrasound beam through th ... Full text Link to item Cite

Two-dimensional echocardiographic assessment of vegetative endocarditis.

Journal Article Circulation · February 1977 Real-time, two-dimensional echocardiography was used to document the presence and assess the size and location of vegetative lesions of the cardiac valves and chambers in seven patients with bacterial endocarditis. Anatomic correlation (surgical or autopsy ... Full text Link to item Cite

A comparison of real-time, two dimensional echocardiography and cineangiography in detecting left ventricular asynergy.

Journal Article Circulation · January 1977 Left ventricular wall motion was assessed in 105 consecutive patients both invasively, using biplane cineangiography, and noninvasively, by a real-time, phased-array, two-dimensional echocardiography system. Ventricular wall motion in five anatomic areas o ... Full text Link to item Cite

Clinical results of real-time ultrasonic scanning of the heart using a phased array system.

Journal Article Yale J Biol Med · 1977 This report describes the operating characteristics and initial clinical results of a new echocardiographic system that produces real-time, high resolution, cross-sectional images of the heart. This system relies upon phased-array principles to rapidly ste ... Link to item Cite

Two-dimensional echocardiographic assessment of mitral stenosis.

Journal Article Circulation · January 1977 A real-time, phased-array, two-dimensional echocardiography system was used to assess mitral valve motion in 30 catheterized patients with pure mitral stenosis. Suitable images for analysis of mitral valve motion were obtained in 25 patients. The valve lea ... Full text Link to item Cite

Basic diagnostic echocardiography.

Journal Article Dis Mon · December 1976 Link to item Cite

Mitral valve prolapse. Two-dimensional echocardiographic and angiographic correlation.

Journal Article Circulation · November 1976 In order to define baseline descriptive criteria for the diagnosis of mitral valve prolapse with cross-sectional echocardiography, 49 patients undergoing catheterization were examined by a real-time, two-dimensional phased array echocardiographic imaging s ... Full text Link to item Cite

Echocardiographic evaluation of tricuspid valve endocarditis: an M mode and two dimensional study.

Journal Article Am J Cardiol · October 1976 Standard M mode echocardiography and a new real time two dimensional echocardiographic imaging system were utilized to follow the progressive anatomic destruction of the tricuspid valve in a patient with bacterial endocarditis. The initial two dimensional ... Full text Link to item Cite

Dynamic cardiac imaging using a phased-array transducer system

Journal Article Proceedings of SPIE - The International Society for Optical Engineering · March 11, 1976 Full text Cite

Cardiac imaging using a phased array ultrasound system. II. Clinical technique and application.

Journal Article Circulation · February 1976 A new two-dimensional ultrasound imaging system capable of producing high resolution tomographic images of the heart in real time has been developed. This system relies on phased array principles to rapidly steer the ultrasound beam through the structures ... Full text Link to item Cite

The hemodynamic simulation of mitral regurgitation in ventricular septal defect after myocardial infarction.

Journal Article Cathet Cardiovasc Diagn · 1976 The development of a ventricular septal defect (VSD) following myocardial infarction is an uncommon complication which clinically can be confused with mitral insufficiency due to infarction of a papillary muscle. The clinical and hemodynamic records of six ... Full text Link to item Cite

A reassessment of the echocardiogram in mitral stenosis.

Journal Article Circulation · October 1975 Echocardiographic and cardiac catheterization findings were compared in 61 patients with mitral stenosis without other significant lesions in an attempt to determine the clinical usefulness of echocardiography in the assessment of such patients. There was ... Full text Link to item Cite

Diastolic vibration of the interventricular septum in aortic insufficiency.

Journal Article Circulation · April 1975 The echocardiograms of 46 patients with aortic insufficiency which manifested typical high frequency vibrations of the anterior mitral valve leaflet were reviewed. All patients had overt clinical evidence of aortic insufficiency which was confirmed by angi ... Full text Link to item Cite

Real time two-dimensional echocardiography

Conference Proceedings of SPIE - The International Society for Optical Engineering · February 1, 1975 Full text Cite

Dynamic cardiac imaging using a phased array transducer system

Journal Article PROC.SOC.PHOTO-OPT.INSTR.ENGIN. · January 1, 1975 Cite

A phased array ultrasound system for cardiac imaging

Journal Article EXCERPTA MEDICA, ICS NO. 363 · January 1, 1975 This report describes the design considerations, performance characteristics and initial clinical results of a new, high-resolution, real-time, two-dimensional ultrasound sector scanner designed specifically for cardiac use. Such a system is unique as it r ... Cite

CARDIOVASCULAR DIAGNOSIS WITH REAL TIME ULTRASOUND IMAGING.

Journal Article Acoust Hologr · January 1, 1975 Real-time imaaging system is described that relies on phased array principles to steer and focus the ultrasound beam in the near field of a linear array of ultrasound transducers. Underlying the development of this system were several design considerations ... Full text Cite

DYNAMIC CARDIAC IMAGING USING A PHASED-ARRAY TRANSDUCER SYSTEM.

Journal Article SPIE Semin Proc · January 1, 1975 This report describes the design considerations, performance characteristics and initial clinical results of a new, high-resolution, real-time, two-dimensional ultrasound sector scanner designed specifically for cardiac use. Such a system is unique as it r ... Cite

REAL TIME TWO-DIMENSIONAL ECHOCARDIOGRAPHY.

Journal Article SPIE Semin Proc · January 1, 1974 A description is given of an ultrasound imaging system which permits visualization of two-dimensional cardiac anatomy in real time. This system relies on phased array principles rather than mechanical means to rapidly steer the ultrasound beam through the ... Cite