Scholars@Duke
Katherine Shepherd Hall

Katherine Shepherd Hall

Associate Professor in Medicine
Medicine, Geriatrics and Palliative Care
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Selected Publications

Sex-specific associations between self-reported physical activity and PTSD among survivors of sexual violence.

Journal Article J Behav Med · April 2024 This study examined sex-specific associations between sexual violence (SV) type and physical activity, and identified associations between PTSD symptoms and physical activity, all among cisgender men and women survivors of SV. Cross-sectional data from men ... Full text Link to item Cite

Exercise Preferences among Men Survivors of Sexual Violence by PTSD and Physical Activity Level: Recommendations for Trauma Informed Practice

Journal Article Journal of Men's Studies · March 1, 2024 This analysis reported interest in exercise programs made for men survivors of sexual violence (SV), preferences for the structure and content of these programs, and comparisons by physical activity level and PTSD status. A cross-sectional survey was condu ... Full text Cite

Trajectories of physical function changes for older veterans with serious mental illness in a clinical exercise program

Journal Article Mental Health and Physical Activity · March 1, 2024 Background and aims: Older persons with serious mental illness (SMI) have compromised physical function (endurance, strength, mobility). Multicomponent exercise is effective at improving function in older adults but has been minimally examined in older peo ... Full text Cite

Posttraumatic stress disorder, trauma, and accelerated biological aging among post-9/11 veterans.

Journal Article Transl Psychiatry · January 6, 2024 People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain this risk is accelerated biological aging, which is associated with the accumulation of chronic diseases, ... Full text Open Access Link to item Cite

Longitudinal analysis of physical function in older adults: The effects of physical inactivity and exercise training.

Journal Article Aging Cell · January 2024 Lack of exercise contributes to systemic inflammation and is a major cause of chronic disease. The long-term impact of initiating and sustaining exercise in late life, as opposed to sustaining a sedentary lifestyle, on whole-body health measures such as ph ... Full text Link to item Cite

Older Veterans' perspectives on participation in a clinical exercise program: A qualitative study of the VA Gerofit exercise program.

Journal Article SAGE Open Med · 2024 OBJECTIVES: We explored the perspectives of older veterans in Gerofit, a Department of Veteran Affairs (VA) supervised clinical exercise program, to understand the factors associated with participation and how the program supported personal health goals. M ... Full text Link to item Cite

Perceived Barriers and Benefits of Exercise Among Men with Histories of Sexual Violence: Impact of PTSD and Physical Activity Status.

Journal Article J Interpers Violence · December 2023 This study reported on perceived benefits and barriers of exercise among men with histories of sexual violence (SV) and compared these perceptions by activity level and post-traumatic stress disorder (PTSD) status. An online, cross-sectional, survey of men ... Full text Link to item Cite

Physical Function Assessment of Older Veterans With Serious Mental Illness.

Journal Article Am J Geriatr Psychiatry · September 2023 OBJECTIVE: To characterize the physical function of older veterans with serious mental illness (SMI) across endurance, strength, and mobility domains. DESIGN: Retrospective analysis of clinical performance data. SETTING: Gerofit program, a national outpati ... Full text Link to item Cite

Impact of Military Affiliation on Exercise Perceptions Among Survivors of Sexual Violence.

Journal Article Mil Med · July 22, 2023 INTRODUCTION: Military service members disproportionately experience sexual violence (SV) and its related health concerns. Although recent work has shown physical activity to be an effective strategy for improving physical and mental health among trauma-ex ... Full text Link to item Cite

Perceived Barriers and Benefits of Exercise Among Women Survivors of Sexual Violence by Physical Activity Level and Posttraumatic Stress Disorder Status.

Journal Article Violence Against Women · June 22, 2023 An online, cross-sectional survey of women survivors of sexual violence (SV; N = 355) gathered information on perceived barriers and benefits of exercise, along with exercise level and posttraumatic stress disorder (PTSD) symptoms. This study reports exerc ... Full text Link to item Cite

Which Types of Stress Are Associated With Accelerated Biological Aging? Comparing Perceived Stress, Stressful Life Events, Childhood Adversity, and Posttraumatic Stress Disorder.

Journal Article Psychosom Med · June 1, 2023 OBJECTIVE: Stress and stressful events are associated with poorer health; however, there are multiple ways to conceptualize and measure stress and stress responses. One physiological mechanism through which stress could result in poorer health is accelerat ... Full text Link to item Cite

Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma Alzheimer's Disease and Related Dementias Biomarkers in the Duke Physical Performance Across the LifeSpan Study.

Journal Article J Alzheimers Dis · 2023 BACKGROUND: The kynurenine pathway (KP) comprises a family of tryptophan-derived metabolites that some studies have reported are associated with poorer cognitive performance and an increased risk of Alzheimer's disease and related dementias (ADRD). OBJECTI ... Full text Open Access Link to item Cite

Retention of older veterans with serious mental illness in a clinical exercise program.

Journal Article Front Psychiatry · 2023 Older adults with serious mental illness (SMI) have compromised physical function that could be improved with exercise; however, retention in exercise programs is a challenge. This study was a retrospective analysis of retention for the 150 older veterans ... Full text Link to item Cite

A pilot study to assess the feasibility of a remotely monitored high-intensity interval training program prior to allogeneic hematopoietic stem cell transplantation.

Journal Article PLoS One · 2023 INTRODUCTION: Although allogeneic hematopoietic stem cell transplantation (HCT) can be a curative therapy for hematologic disorders, it is associated with treatment-related complications and losses in cardiorespiratory fitness and physical function. High-i ... Full text Link to item Cite

Exercise preferences among women survivors of sexual violence by PTSD and physical activity level: Implications and recommendations for trauma-informed practice

Journal Article Mental Health and Physical Activity · October 1, 2022 Background: This analysis reported (1) interest in exercise programs made for women survivors of sexual violence (SV), (2) preferences for the structure and content of these programs, and (3) comparisons of interest and preferences by physical activity and ... Full text Cite

Geriatric Assessment Reveals Actionable Impairments in Hematopoietic Stem Cell Transplantation Candidates Age 18 to 80 Years.

Journal Article Transplant Cell Ther · August 2022 Allogeneic hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for both malignant and nonmalignant hematologic diseases; however, reported rates of treatment-related mortality approach 30%. Outcomes are worse in patients who b ... Full text Link to item Cite

Cost and Quality of Life Outcomes of the STepped Exercise Program for Patients With Knee OsteoArthritis Trial.

Journal Article Value Health · April 2022 OBJECTIVES: This study aimed to evaluate the cost-effectiveness of the randomized clinical trial STEP-KOA (STepped Exercise Program for patients with Knee OsteoArthritis). METHODS: The trial included 230 intervention and 115 control participants from 2 Vet ... Full text Link to item Cite

The Sickle Cell Disease Functional Assessment (SCD-FA) tool: a feasibility pilot study.

Journal Article Pilot Feasibility Stud · March 4, 2022 BACKGROUND: The life expectancy for individuals with sickle cell disease (SCD) has greatly increased over the last 50 years. Adults with SCD experience multiple complications such as cardiopulmonary disease, strokes, and avascular necrosis that lead to lim ... Full text Open Access Link to item Cite

Diet quality and exercise in older veterans with PTSD: a pilot study.

Journal Article Transl Behav Med · December 14, 2021 Older veterans with posttraumatic stress disorder (PTSD) are at increased risk of obesity and cardiometabolic disease. Physical activity and healthy eating are two behaviors that impact health, functional independence, and disease risk in later life, yet f ... Full text Open Access Link to item Cite

A template for physical resilience research in older adults: Methods of the PRIME-KNEE study.

Journal Article J Am Geriatr Soc · November 2021 BACKGROUND: Older adults with similar health conditions often experience widely divergent outcomes following health stressors. Variable recovery after a health stressor may be due in part to differences in biological mechanisms at the molecular, cellular, ... Full text Link to item Cite

Sex-specific associations between self-reported physical activity and PTSD among survivors of sexual violence.

Journal Article J Behav Med · April 2024 This study examined sex-specific associations between sexual violence (SV) type and physical activity, and identified associations between PTSD symptoms and physical activity, all among cisgender men and women survivors of SV. Cross-sectional data from men ... Full text Link to item Cite

Exercise Preferences among Men Survivors of Sexual Violence by PTSD and Physical Activity Level: Recommendations for Trauma Informed Practice

Journal Article Journal of Men's Studies · March 1, 2024 This analysis reported interest in exercise programs made for men survivors of sexual violence (SV), preferences for the structure and content of these programs, and comparisons by physical activity level and PTSD status. A cross-sectional survey was condu ... Full text Cite

Trajectories of physical function changes for older veterans with serious mental illness in a clinical exercise program

Journal Article Mental Health and Physical Activity · March 1, 2024 Background and aims: Older persons with serious mental illness (SMI) have compromised physical function (endurance, strength, mobility). Multicomponent exercise is effective at improving function in older adults but has been minimally examined in older peo ... Full text Cite

Posttraumatic stress disorder, trauma, and accelerated biological aging among post-9/11 veterans.

Journal Article Transl Psychiatry · January 6, 2024 People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain this risk is accelerated biological aging, which is associated with the accumulation of chronic diseases, ... Full text Open Access Link to item Cite

Longitudinal analysis of physical function in older adults: The effects of physical inactivity and exercise training.

Journal Article Aging Cell · January 2024 Lack of exercise contributes to systemic inflammation and is a major cause of chronic disease. The long-term impact of initiating and sustaining exercise in late life, as opposed to sustaining a sedentary lifestyle, on whole-body health measures such as ph ... Full text Link to item Cite

Older Veterans' perspectives on participation in a clinical exercise program: A qualitative study of the VA Gerofit exercise program.

Journal Article SAGE Open Med · 2024 OBJECTIVES: We explored the perspectives of older veterans in Gerofit, a Department of Veteran Affairs (VA) supervised clinical exercise program, to understand the factors associated with participation and how the program supported personal health goals. M ... Full text Link to item Cite

Perceived Barriers and Benefits of Exercise Among Men with Histories of Sexual Violence: Impact of PTSD and Physical Activity Status.

Journal Article J Interpers Violence · December 2023 This study reported on perceived benefits and barriers of exercise among men with histories of sexual violence (SV) and compared these perceptions by activity level and post-traumatic stress disorder (PTSD) status. An online, cross-sectional, survey of men ... Full text Link to item Cite

Physical Function Assessment of Older Veterans With Serious Mental Illness.

Journal Article Am J Geriatr Psychiatry · September 2023 OBJECTIVE: To characterize the physical function of older veterans with serious mental illness (SMI) across endurance, strength, and mobility domains. DESIGN: Retrospective analysis of clinical performance data. SETTING: Gerofit program, a national outpati ... Full text Link to item Cite

Impact of Military Affiliation on Exercise Perceptions Among Survivors of Sexual Violence.

Journal Article Mil Med · July 22, 2023 INTRODUCTION: Military service members disproportionately experience sexual violence (SV) and its related health concerns. Although recent work has shown physical activity to be an effective strategy for improving physical and mental health among trauma-ex ... Full text Link to item Cite

Perceived Barriers and Benefits of Exercise Among Women Survivors of Sexual Violence by Physical Activity Level and Posttraumatic Stress Disorder Status.

Journal Article Violence Against Women · June 22, 2023 An online, cross-sectional survey of women survivors of sexual violence (SV; N = 355) gathered information on perceived barriers and benefits of exercise, along with exercise level and posttraumatic stress disorder (PTSD) symptoms. This study reports exerc ... Full text Link to item Cite

Which Types of Stress Are Associated With Accelerated Biological Aging? Comparing Perceived Stress, Stressful Life Events, Childhood Adversity, and Posttraumatic Stress Disorder.

Journal Article Psychosom Med · June 1, 2023 OBJECTIVE: Stress and stressful events are associated with poorer health; however, there are multiple ways to conceptualize and measure stress and stress responses. One physiological mechanism through which stress could result in poorer health is accelerat ... Full text Link to item Cite

Tryptophan Metabolism and Neurodegeneration: Longitudinal Associations of Kynurenine Pathway Metabolites with Cognitive Performance and Plasma Alzheimer's Disease and Related Dementias Biomarkers in the Duke Physical Performance Across the LifeSpan Study.

Journal Article J Alzheimers Dis · 2023 BACKGROUND: The kynurenine pathway (KP) comprises a family of tryptophan-derived metabolites that some studies have reported are associated with poorer cognitive performance and an increased risk of Alzheimer's disease and related dementias (ADRD). OBJECTI ... Full text Open Access Link to item Cite

Retention of older veterans with serious mental illness in a clinical exercise program.

Journal Article Front Psychiatry · 2023 Older adults with serious mental illness (SMI) have compromised physical function that could be improved with exercise; however, retention in exercise programs is a challenge. This study was a retrospective analysis of retention for the 150 older veterans ... Full text Link to item Cite

A pilot study to assess the feasibility of a remotely monitored high-intensity interval training program prior to allogeneic hematopoietic stem cell transplantation.

Journal Article PLoS One · 2023 INTRODUCTION: Although allogeneic hematopoietic stem cell transplantation (HCT) can be a curative therapy for hematologic disorders, it is associated with treatment-related complications and losses in cardiorespiratory fitness and physical function. High-i ... Full text Link to item Cite

Exercise preferences among women survivors of sexual violence by PTSD and physical activity level: Implications and recommendations for trauma-informed practice

Journal Article Mental Health and Physical Activity · October 1, 2022 Background: This analysis reported (1) interest in exercise programs made for women survivors of sexual violence (SV), (2) preferences for the structure and content of these programs, and (3) comparisons of interest and preferences by physical activity and ... Full text Cite

Geriatric Assessment Reveals Actionable Impairments in Hematopoietic Stem Cell Transplantation Candidates Age 18 to 80 Years.

Journal Article Transplant Cell Ther · August 2022 Allogeneic hematopoietic stem cell transplantation (HCT) is a potentially curative treatment for both malignant and nonmalignant hematologic diseases; however, reported rates of treatment-related mortality approach 30%. Outcomes are worse in patients who b ... Full text Link to item Cite

Cost and Quality of Life Outcomes of the STepped Exercise Program for Patients With Knee OsteoArthritis Trial.

Journal Article Value Health · April 2022 OBJECTIVES: This study aimed to evaluate the cost-effectiveness of the randomized clinical trial STEP-KOA (STepped Exercise Program for patients with Knee OsteoArthritis). METHODS: The trial included 230 intervention and 115 control participants from 2 Vet ... Full text Link to item Cite

The Sickle Cell Disease Functional Assessment (SCD-FA) tool: a feasibility pilot study.

Journal Article Pilot Feasibility Stud · March 4, 2022 BACKGROUND: The life expectancy for individuals with sickle cell disease (SCD) has greatly increased over the last 50 years. Adults with SCD experience multiple complications such as cardiopulmonary disease, strokes, and avascular necrosis that lead to lim ... Full text Open Access Link to item Cite

Diet quality and exercise in older veterans with PTSD: a pilot study.

Journal Article Transl Behav Med · December 14, 2021 Older veterans with posttraumatic stress disorder (PTSD) are at increased risk of obesity and cardiometabolic disease. Physical activity and healthy eating are two behaviors that impact health, functional independence, and disease risk in later life, yet f ... Full text Open Access Link to item Cite

A template for physical resilience research in older adults: Methods of the PRIME-KNEE study.

Journal Article J Am Geriatr Soc · November 2021 BACKGROUND: Older adults with similar health conditions often experience widely divergent outcomes following health stressors. Variable recovery after a health stressor may be due in part to differences in biological mechanisms at the molecular, cellular, ... Full text Link to item Cite

Patient-centered behavioral services for women veterans with mental health conditions.

Journal Article Transl Behav Med · September 15, 2021 The Veterans Health Administration (VHA) is undergoing a transformational shift from disease-focused care to a Whole Health model that emphasizes physical, mental, emotional, and spiritual health and well-being. As this shift is occurring, women veterans u ... Full text Link to item Cite

Towards "mobility is medicine": Socioecological factors and hospital mobility in older adults.

Journal Article J Am Geriatr Soc · July 2021 BACKGROUND: Understanding the factors that influence hospital mobility, especially in the context of a heightened focus on falls prevention, is needed to improve care. OBJECTIVE: This qualitative study uses a socioecological framework to explore factors th ... Full text Link to item Cite

Physical activity to address multimorbidity among survivors of sexual violence: A comprehensive narrative review

Journal Article Psychology of Sport and Exercise · July 1, 2021 Background: Sexual Violence (SV) is highly prevalent and experienced by women and men throughout the United States and world. Survivors of SV often experience poor mental and physical health, and poor health-related quality of life. Studies have explored t ... Full text Cite

Qualitative Analysis of a Supervised Exercise Program for Older Veterans With PTSD.

Journal Article Am J Geriatr Psychiatry · June 2021 OBJECTIVE: Older veterans with post-traumatic stress disorder (PTSD) experience substantial physical and mental health challenges. Given the well-known and wide-reaching benefits of exercise, exploring the impact of interventions designed specifically for ... Full text Link to item Cite

PTSD Improvement Associated with Social Connectedness in Gerofit Veterans Exercise Program.

Journal Article J Am Geriatr Soc · April 2021 OBJECTIVE: Post-traumatic stress disorder (PTSD) is common in Veterans. Symptoms can perpetuate into late life, negatively impacting physical and mental health. Exercise and social support are beneficial in treating anxiety disorders such as PTSD in the ge ... Full text Link to item Cite

Trauma-informed exercise for women survivors of sexual violence.

Journal Article Transl Behav Med · March 16, 2021 Compared to their male counterparts, women experience alarmingly high rates of sexual violence (SV). Nearly 20% of women in the USA have been victims of SV, and prevalence of sexual assault among female service members is reported to be even higher, up to ... Full text Link to item Cite

Stepped Exercise Program for Patients With Knee Osteoarthritis : A Randomized Controlled Trial.

Journal Article Ann Intern Med · March 2021 BACKGROUND: Evidence-based models are needed to deliver exercise-related services for knee osteoarthritis efficiently and according to patient needs. OBJECTIVE: To examine a stepped exercise program for patients with knee osteoarthritis (STEP-KOA). DESIGN: ... Full text Link to item Cite

Assessing Moderate to Vigorous Physical Activity in Older Adults: Validity of a Commercial Activity Tracker.

Journal Article Front Sports Act Living · 2021 Purpose: Despite the potential for commercial activity devices to promote moderate to vigorous physical activity (MVPA), limited information is available in older adults, a high-priority target population with unique gait dynamics and energy expenditure. T ... Full text Link to item Cite

Warrior Wellness: A Randomized Controlled Pilot Trial of the Effects of Exercise on Physical Function and Clinical Health Risk Factors in Older Military Veterans With PTSD.

Journal Article J Gerontol A Biol Sci Med Sci · October 15, 2020 BACKGROUND: Military veterans living with post-traumatic stress disorder (PTSD) face significant physical and functional health disparities, which are often aggravated over time and in the context aging. Evidence has shown that physical activity can positi ... Full text Open Access Link to item Cite

Pilot randomized controlled trial of exercise training for older veterans with PTSD.

Journal Article J Behav Med · August 2020 Exercise training positively impacts mental health, yet remains untested in older adults with posttraumatic stress disorder (PTSD). We conducted a randomized controlled pilot trial to test the feasibility and acceptability of exercise training in older vet ... Full text Open Access Link to item Cite

Determinants of Maintenance and Recovery of Function in a Representative Older Community-Resident Biracial Sample.

Journal Article J Am Med Dir Assoc · August 2020 OBJECTIVES: Focus on decline in performance of activities of daily living (ADL) has not been matched by studies of recovery of function. Advised by a broad conceptual model of physical resilience, we ascertain characteristics that identify (1) maintenance, ... Full text Link to item Cite

Systematic review of the prospective association of daily step counts with risk of mortality, cardiovascular disease, and dysglycemia.

Journal Article Int J Behav Nutr Phys Act · June 20, 2020 BACKGROUND: Daily step counts is an intuitive metric that has demonstrated success in motivating physical activity in adults and may hold potential for future public health physical activity recommendations. This review seeks to clarify the pattern of the ... Full text Link to item Cite

Physical Activity in the Hospital: Documentation and Influence on Venous Thromboembolism Prophylaxis.

Journal Article J Aging Phys Act · April 24, 2020 This study describes the availability of physical activity information in the electronic health record, explores how electronic health record documentation correlates with accelerometer-derived physical activity data, and examines whether measured physical ... Full text Link to item Cite

Accelerometer-Measured Hospital Physical Activity and Hospital-Acquired Disability in Older Adults.

Journal Article J Am Geriatr Soc · February 2020 BACKGROUND: Hospital-acquired disability (HAD) is common and often related to low physical activity while in the hospital. OBJECTIVE: To examine whether wearable hospital activity trackers can be used to predict HAD. DESIGN: A prospective observational stu ... Full text Link to item Cite

Physical Function Assessment in Older Hemodialysis Patients.

Journal Article Kidney Med · 2020 RATIONALE & OBJECTIVE: Physical function is not routinely measured in older adults receiving dialysis. We evaluated the appropriateness of repeated measurements of physical function, including Short Physical Performance Battery (SPPB), handgrip strength, a ... Full text Link to item Cite

Geriatric assessment for older adults with sickle cell disease: protocol for a prospective cohort pilot study.

Journal Article Pilot Feasibility Stud · 2020 BACKGROUND: The life expectancy for people with sickle cell disease (SCD) has improved tremendously over the last 50 years. This population experiences hemolysis and vaso-occlusion in multiple organs that lead to complications such as cardiopulmonary disea ... Full text Link to item Cite

Rapid Transition to Telehealth Group Exercise and Functional Assessments in Response to COVID-19.

Journal Article Gerontol Geriatr Med · 2020 Exercise is critical for health maintenance in late life. The COVID-19 shelter in place and social distancing orders resulted in wide-scale interruptions of exercise therapies, placing older adults at risk for the consequences of decreased mobilization. Th ... Full text Open Access Link to item Cite

Composite measures of physical activity and pain associate better with functional assessments than pain alone in knee osteoarthritis.

Journal Article Clin Rheumatol · August 2019 INTRODUCTION: Recent research showed that physical activity (PA)-adjusted pain measures were more strongly associated with radiographic osteoarthritis (OA) severity than an unadjusted pain measure. This exploratory study examined whether PA-adjusted pain m ... Full text Link to item Cite

Insights Following Implementation of an Exercise Intervention in Older Veterans with PTSD.

Journal Article Int J Environ Res Public Health · July 23, 2019 Individuals with post-traumatic stress disorder (PTSD) face numerous barriers to exercise. Little is known about behavioral strategies to promote participation in this population. This is a secondary analysis of individual barriers and goals, exercise pres ... Full text Link to item Cite

STepped exercise program for patients with knee OsteoArthritis (STEP-KOA): protocol for a randomized controlled trial.

Journal Article BMC Musculoskelet Disord · May 28, 2019 BACKGROUND: Physical therapy (PT) and other exercise-based interventions are core components of care for knee osteoarthritis (OA), but both are underutilized, and some patients have limited access to PT services. This clinical trial is examining a STepped ... Full text Open Access Link to item Cite

Physical activity promotion in women with PTSD: What we need for progress.

Journal Article Psychol Sport Exerc · March 2019 OBJECTIVES: Researchers explore considerations for studying exercise promotion in women with post-traumatic stress disorder (PTSD). DESIGN: Researchers evaluated current studies on exercise promotion and PTSD. METHOD: Presents critical reflections on (1) t ... Link to item Cite

Effects of Structured Exercise Interventions for Older Adults Hospitalized With Acute Medical Illness: A Systematic Review.

Journal Article J Aging Phys Act · April 1, 2018 This review examined effects of structured exercise (aerobic walking, with or without complementary modes of exercise) on cardiorespiratory measures, mobility, functional status, healthcare utilization, and quality of life in older adults (≥60 years) hospi ... Full text Link to item Cite

The Warrior Wellness Study: A Randomized Controlled Exercise Trial for Older Veterans with PTSD.

Journal Article Transl J Am Coll Sports Med · March 15, 2018 Posttraumatic stress disorder (PTSD) affects up to 30% of military veterans. Older veterans, many of whom have lived with PTSD symptoms for several decades, report a number of negative health outcomes. Despite the demonstrated benefits of regular exercise ... Full text Open Access Link to item Cite

Physical Performance Across the Adult Life Span: Correlates With Age and Physical Activity.

Journal Article J Gerontol A Biol Sci Med Sci · April 1, 2017 BACKGROUND: A number of large-scale population studies have provided valuable information about physical performance in aged individuals; however, there is little information about trajectories of function and associations with age across the adult life sp ... Full text Link to item Cite

Economic Analysis of Primary Care-Based Physical Activity Counseling in Older Men: The VA-LIFE Trial.

Journal Article J Am Geriatr Soc · March 2017 OBJECTIVES: To perform an economic evaluation of a primary care-based physical activity counseling intervention that improved physical activity levels and rapid gait speed in older veterans. DESIGN: Secondary objective of randomized trial that assessed the ... Full text Open Access Link to item Cite

The Impact of Interventions that Integrate Accelerometers on Physical Activity and Weight Loss: A Systematic Review.

Journal Article Ann Behav Med · February 2017 BACKGROUND: Regular physical activity is important for improving and maintaining health, but sedentary behavior is difficult to change. Providing objective, real-time feedback on physical activity with wearable motion-sensing technologies (activity monitor ... Full text Link to item Cite

Military and veteran health behavior research and practice: challenges and opportunities.

Journal Article J Behav Med · February 2017 There are 2.1 million current military servicemembers and 21 million living veterans in the United States. Although they were healthier upon entering military service compared to the general U.S. population, in the longer term veterans tend to be of equiva ... Full text Link to item Cite

Physical Activity Counseling Promotes Physical and Psychological Resilience in Older Veterans with Posttraumatic Stress Disorder.

Journal Article Ment Health Phys Act · October 2016 UNLABELLED: Individuals with posttraumatic stress disorder (PTSD) have elevated rates of morbidity, and a sedentary lifestyle can cause and aggravate the physical health needs of adults with PTSD. The primary aim of this paper was to explore the impact of ... Full text Open Access Link to item Cite

Group Versus Individual Physical Therapy for Veterans With Knee Osteoarthritis: Randomized Clinical Trial.

Journal Article Phys Ther · May 2016 BACKGROUND: Efficient approaches are needed for delivering nonpharmacological interventions for management of knee osteoarthritis (OA). OBJECTIVE: This trial compared group-based versus individual physical therapy interventions for management of knee OA. D ... Full text Open Access Link to item Cite

Individual and contextual correlates of physical activity among a clinical sample of United States Veterans.

Journal Article Soc Sci Med · October 2015 RATIONALE: Veterans, especially those using U.S. Department of Veterans Affairs (VA) healthcare, have poorer health than the general population. In addition, Veterans using VA services are more likely than non-VA users to be physically inactive. Little is ... Full text Link to item Cite

PTSD and depression symptoms are associated with binge eating among US Iraq and Afghanistan veterans.

Journal Article Eat Behav · April 2015 OBJECTIVE: US Iraq and Afghanistan Veterans with post-traumatic stress disorder (PTSD) and depression are at increased risk for obesity. Understanding the contribution of health behaviors to this relationship will enhance efforts to prevent and reduce obes ... Full text Link to item Cite

Post-traumatic stress disorder, physical activity, and eating behaviors.

Journal Article Epidemiol Rev · 2015 Post-traumatic stress disorder (PTSD), a prevalent and costly psychiatric disorder, is associated with high rates of obesity and cardiometabolic diseases. Many studies have examined PTSD and risky behaviors (e.g., smoking, alcohol/substance abuse); far few ... Full text Link to item Cite

Self-efficacy for exercise, more than disease-related factors, is associated with objectively assessed exercise time and sedentary behaviour in rheumatoid arthritis.

Journal Article Scand J Rheumatol · 2015 OBJECTIVES: Until recently, reports of physical activity in rheumatoid arthritis (RA) were limited to self-report methods and/or leisure-time physical activity. Our objectives were to assess, determine correlates of, and compare to well-matched controls bo ... Full text Link to item Cite

Differences between completely physically inactive and low active older men and their response to an exercise intervention: the Veterans LIFE study.

Journal Article Healthy Aging Res · 2015 BACKGROUND: Physical activity interventions typically do not report behavioral changes in activity sub-groups. The aim of this study was to compare baseline differences and changes in physical activity between truly physically inactive men and low active m ... Full text Open Access Link to item Cite

Activity-related energy expenditure in older adults: a call for more research.

Journal Article Med Sci Sports Exerc · December 2014 The purposes of this article were to 1) provide an overview of the science of physical activity-related energy expenditure in older adults (≥65 yr), 2) offer suggestions for future research and guidelines for how scientists should be reporting their result ... Full text Link to item Cite

The role of symptoms and self-efficacy in predicting physical activity change among older adults with arthritis.

Journal Article J Phys Act Health · March 2014 BACKGROUND: Physical and psychological symptoms limit physical activity for people with arthritis. This study examined if self-efficacy mediated a relationship between symptom and physical activity (PA) frequency change. METHODS: This was a secondary analy ... Full text Link to item Cite

PTSD is negatively associated with physical performance and physical function in older overweight military Veterans.

Journal Article J Rehabil Res Dev · 2014 This study examines the effect of posttraumatic stress disorder (PTSD) on function and physical performance in older overweight military Veterans with comorbid conditions. This is a secondary data analysis of older Veterans (mean age = 62.9 yr) participati ... Full text Open Access Link to item Cite

Group physical therapy for veterans with knee osteoarthritis: study design and methodology.

Journal Article Contemp Clin Trials · March 2013 Featured Publication Physical therapy (PT) is a key component of treatment for knee osteoarthritis (OA) and can decrease pain and improve function. Given the expected rise in prevalence of knee OA and the associated demand for treatment, there is a need for models of care that ... Full text Open Access Link to item Cite

METs and accelerometry of walking in older adults: standard versus measured energy cost.

Journal Article Med Sci Sports Exerc · March 2013 Featured Publication PURPOSE: This study aimed to measure the metabolic cost (METs) of walking activities in older adults, to examine the relationship between accelerometer output and METs across walking activities, and to compare measured MET values in older adults with the M ... Full text Link to item Cite

Validity of the multidimensional outcome expectations for exercise scale in continuing-care retirement communities.

Journal Article J Aging Phys Act · October 2012 Featured Publication OBJECTIVE: The current study examined the psychometric properties and validity of the Multidimensional Outcome Expectations for Exercise Scale (MOEES) in a sample of older adults with physical and functional comorbidities. METHODS: Confirmatory factor anal ... Full text Link to item Cite

Enhanced fitness: a randomized controlled trial of the effects of home-based physical activity counseling on glycemic control in older adults with prediabetes mellitus.

Journal Article J Am Geriatr Soc · September 2012 Featured Publication OBJECTIVES: To determine whether a home-based multicomponent physical activity counseling (PAC) intervention is effective in reducing glycemic measures in older outpatients with prediabetes mellitus. DESIGN: Controlled clinical trial. SETTING: Primary care ... Full text Open Access Link to item Cite

Lessons learned when innovations go awry: a baseline description of a behavioral trial-the Enhancing Fitness in Older Overweight Veterans with Impaired Fasting Glucose study.

Journal Article Transl Behav Med · November 2011 Featured Publication Individuals diagnosed with impaired glucose tolerance (i.e., prediabetes) are at increased risk for developing diabetes. We proposed a clinical trial with a novel adaptive randomization designed to examine the impact of a home-based physical activity (PA) ... Full text Open Access Link to item Cite

Examining indirect associations between physical activity, function, and disability in independent- and assisted-living residents.

Journal Article J Phys Act Health · July 2011 Featured Publication BACKGROUND: Few studies have examined physical activity behavior and its associated outcomes in older adults living in retirement communities. Guided by the disablement model and social cognitive theory, we tested a cross-sectional model in which physical ... Full text Link to item Cite

Long-term changes in physical activity following a one-year home-based physical activity counseling program in older adults with multiple morbidities.

Journal Article J Aging Res · December 26, 2010 Featured Publication This study assessed the sustained effect of a physical activity (PA) counseling intervention on PA one year after intervention, predictors of sustained PA participation, and three classes of post-intervention PA trajectories (improvers, maintainers, and de ... Full text Open Access Link to item Cite

Understanding the impact of the environment on physical activity

Journal Article · December 1, 2010 Featured Publication As the number of aged persons in the population grows, it is important to identifyand understand those lifestyle components that contribute to an improved quality of lifeand maintenance of functional independence. Benefits of regular physical activity incl ... Cite

Individual progress toward self-selected goals among older adults enrolled in a physical activity counseling intervention.

Journal Article J Aging Phys Act · October 2010 Featured Publication The purpose of this study was to examine what happens to goals over the course of a physical activity counseling trial in older veterans. At baseline, participants (N = 313) identified 1 health-related goal and 1 walking goal for their participation in the ... Full text Link to item Cite

Change in goal ratings as a mediating variable between self-efficacy and physical activity in older men.

Journal Article Ann Behav Med · June 2010 Featured Publication BACKGROUND: Few studies have examined the associations between exercise self-efficacy, goals, and physical activity over time. PURPOSE: This study examines whether self-selected goals mediate the changes in exercise self-efficacy on physical activity over ... Full text Open Access Link to item Cite

Individual, social environmental and physical environmental barriers to achieving 10 000 steps per day among older women.

Journal Article Health Educ Res · June 2010 Featured Publication UNLABELLED: This study examined the determinants of attaining/not attaining 10 000 steps per day among older women. METHODS: Daily step counts over 7 days were measured using accelerometry. Self-reported environmental characteristics, self-efficacy, social ... Full text Link to item Cite

Functional connectivity: a source of variance in the association between cardiorespiratory fitness and cognition?

Journal Article Neuropsychologia · April 2010 Over the next 20 years the number of Americans diagnosed with dementia is expected to more than double (CDC, 2007). It is, therefore, an important public health initiative to understand what factors contribute to the longevity of a healthy mind. Both defau ... Full text Link to item Cite

Is diabetes associated with poorer self-efficacy and motivation for physical activity in older adults with arthritis?

Journal Article Scand J Rheumatol · 2010 Featured Publication OBJECTIVES: The primary aim was to explore whether arthritis is associated with poorer self-efficacy and motivation for, and participation in, two specific types of physical activity (PA): endurance training (ET) and strength training (ST). A further objec ... Full text Link to item Cite

Aerobic fitness is associated with hippocampal volume in elderly humans.

Journal Article Hippocampus · October 2009 Deterioration of the hippocampus occurs in elderly individuals with and without dementia, yet individual variation exists in the degree and rate of hippocampal decay. Determining the factors that influence individual variation in the magnitude and rate of ... Full text Link to item Cite

Preliminary evidence that self-efficacy predicts physical activity in multiple sclerosis.

Journal Article Int J Rehabil Res · September 2009 Individuals with multiple sclerosis (MS) are less physically active than non diseased people. One method for increasing physical activity levels involves the identification of factors that correlate with physical activity and that are modifiable by a well ... Full text Link to item Cite

Trajectory of declines in physical activity in community-dwelling older women: social cognitive influences.

Journal Article J Gerontol B Psychol Sci Soc Sci · September 2009 Featured Publication Studies examining physical activity behavior suggest that activity levels decline with age. Such declines are particularly problematic among older adults in light of the research suggesting a protective effect of physical activity on numerous physical heal ... Full text Link to item Cite

Dedifferentiation in the visual cortex: an fMRI investigation of individual differences in older adults.

Journal Article Brain Res · December 9, 2008 Dedifferentiation, or decreased processing specificity, has been suggested to represent a ubiquitous characteristic of cognitive aging. In this study, we examined both age-related differences and intra-group differences in neural specificity in the ventral ... Full text Link to item Cite

Pathways from physical activity to quality of life in older women.

Journal Article Ann Behav Med · August 2008 BACKGROUND: In spite of consistent evidence to suggest that being more physically active is associated with enhanced quality of life (QOL), there have been remarkably few attempts to determine the possible underlying mechanisms in this relationship. PURPOS ... Full text Link to item Cite

Self-efficacy and environmental correlates of physical activity among older women and women with multiple sclerosis.

Journal Article Health Educ Res · August 2008 Physical inactivity is a major health problem in the United States, particularly in elderly and disabled populations. Little research exists examining the relationships between aspects of the built environment and physical activity in older adults and indi ... Full text Link to item Cite

Self-efficacy effects on neuroelectric and behavioral indices of action monitoring in older adults.

Journal Article Neurobiol Aging · July 2008 The relationships between self-efficacy (SE), i.e., beliefs in personal capabilities, and behavioral and neuroelectric (i.e., ERN, Pe) indices of action monitoring were investigated in 40 older adults (13 male) during the completion of a flanker paradigm p ... Full text Link to item Cite

Self-efficacy, physical activity and cognition in older adults

Conference ANNALS OF BEHAVIORAL MEDICINE · March 1, 2008 Link to item Cite

Neighborhood satisfaction, functional limitations, and self-efficacy influences on physical activity in older women.

Journal Article Int J Behav Nutr Phys Act · February 27, 2008 BACKGROUND: Perceptions of one's environment and functional status have been linked to physical activity in older adults. However, little is known about these associations over time, and even less about the possible mediators of this relationship. We exami ... Full text Link to item Cite

Effects of change in physical activity on physical function limitations in older women: mediating roles of physical function performance and self-efficacy.

Journal Article J Am Geriatr Soc · December 2007 OBJECTIVES: To examine the hypothesis that changes in self-efficacy and functional performance mediate, in part, the beneficial effect of physical activity on functional limitations over time. DESIGN: Prospective, observational study. SETTING: Community-ba ... Full text Link to item Cite

Enhancing physical activity adherence and well-being in multiple sclerosis: a randomised controlled trial.

Journal Article Mult Scler · June 2007 Individuals with multiple sclerosis (MS) are more sedentary than the general population, increasing their propensity for reduced functional ability, mobility, and activities of daily living. Self-efficacy has been one of the most consistent determinants of ... Full text Link to item Cite

Long-term follow-up of physical activity behavior in older adults.

Journal Article Health Psychol · May 2007 OBJECTIVE: To examine the contribution of social-cognitive factors (self-efficacy and affect) in predicting long-term physical activity in a sample of older adults (N=174). DESIGN: A prospective design assessed physical activity and psychosocial variables ... Full text Link to item Cite

State of the Art Review: Advances in Physical Activity and Mental Health: Quality of Life

Journal Article American Journal of Lifestyle Medicine · January 1, 2007 Biomedical advances and the practice of preventive health behaviors have resulted in an unprecedented growth in the older population of the United States, a trend projected to continue during the next several decades. However, the addition of years to life ... Full text Cite

Physical activity and functional limitations in older women: influence of self-efficacy.

Journal Article J Gerontol B Psychol Sci Soc Sci · September 2006 This study examined the role of self-efficacy and physical function performance in the relationship between physical activity and functional limitations. Older women (age, M = 68.2 years) completed measures of physical activity, self-efficacy, physical fun ... Full text Link to item Cite

Physical activity and quality of life in older adults: influence of health status and self-efficacy.

Journal Article Ann Behav Med · February 2006 BACKGROUND: Physical activity has been positively linked to quality of life (QOL) in older adults. Measures of health status and global well-being represent common methods of assessing QOL outcomes, yet little has been done to determine the nature of the r ... Full text Link to item Cite

Self-efficacy and ERN in older adults

Conference PSYCHOPHYSIOLOGY · January 1, 2006 Link to item Cite

APOE genotype, lipids and risk for Alzheimer's disease in the Yoruba

Conference JOURNAL OF THE NEUROLOGICAL SCIENCES · November 15, 2005 Link to item Cite

Measuring disability and function in older women: psychometric properties of the late-life function and disability instrument.

Journal Article J Gerontol A Biol Sci Med Sci · July 2005 BACKGROUND: The recent development of the Late-Life Function and Disability Instrument (LL-FDI) was an important contribution to the measurement of function and disability in older adults. The present study examined the psychometric properties and construc ... Full text Link to item Cite

Physical Activity And Functional Limitation In Older Women

Conference Medicine & Science in Sports & Exercise · May 2005 Full text Cite

Maintenance Of Long-term Physical Activity In Older Adults

Conference Medicine & Science in Sports & Exercise · May 2005 Full text Cite

Angiotensin II attenuates chemical hypoxia-induced caspase-3 activation in primary cortical neuronal cultures.

Journal Article Brain Res Bull · January 15, 2004 In this study we determined whether caspase-3 is required in mouse cortical neurons for sodium azide-mediated apoptosis. Primary cortical neuronal cultures were treated with a cell permeable caspase-3 inhibitor, DEVD (1 nM-100 fM), prior to sodium azide-in ... Full text Link to item Cite

Angiotensin protects cortical neurons from hypoxic-induced apoptosis via the angiotensin type 2 receptor.

Journal Article Brain Res Mol Brain Res · March 28, 2002 The effects of angiotensin on mouse cortical neuronal cultures exposed to chemical-induced hypoxia was investigated. Cultures exposed to 10 mM sodium azide for 5 min showed a 17% increase in apoptosis when assayed 24 h postinsult. The N-methyl-D-aspartate ... Full text Link to item Cite