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Laura Jane Fish
Associate Professor in Family Medicine and Community Health
Journal ArticleJ Gen Intern Med · May 2026
BACKGROUND: When patients with multimorbidity (≥ 2 chronic diseases) are diagnosed with cancer, their adherence to non-cancer medications declines. Nonadherence in this patient population has been linked to an increased risk of disease progression, hospita ...
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Journal ArticleEpidemiology · April 1, 2026
BACKGROUND: Although death certificates are widely used to study mortality in the general population, their use to study mortality among individuals with military service has been limited in part by a lack of information on the validity of military service ...
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Journal ArticleJ Sex Med · January 5, 2026
BACKGROUND: The importance of training healthcare providers to care for sexual and gender minority (SGM) patients is highlighted in the medical education literature; however, best practices for inclusion of this content in medical education are not well de ...
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Journal ArticleJAMA Netw Open · January 2, 2026
IMPORTANCE: Hospital global budgets gained attention as a strategy to constrain costs and improve outcomes. The Maryland all-payer model (APM), initiated in 2014 as a global budget revenue model, is an example of full-risk payment reform; yet frontline sur ...
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Journal ArticleTransplant Cell Ther · January 2026
BACKGROUND: Chlorhexidine gluconate (CHG) bathing is recommended for infection prevention in hematopoietic cell transplantation (HCT) patients. As more centers transition HCT care to outpatient settings, understanding patients' perceptions of CHG bathing f ...
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Journal ArticlePalliative Medicine Reports · January 2026
Purpose:Black patients with acute myeloid leukemia (AML) experience disparate outcomes, and factors such as structural racism and differential treatment access have been i ...
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Journal ArticlePatient Educ Couns · October 2025
BACKGROUND: Family-centered rounds (FCR), multi-disciplinary rounds at bedside that involve the patient and family, has become the standard of care in pediatric hospitalizations. Caregiver participation on FCR improves shared-decision making and communicat ...
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Journal ArticleAm J Kidney Dis · July 2025
RATIONALE & OBJECTIVE: Cardiac arrest is the leading cause of death for hemodialysis patients and often occurs within outpatient dialysis units. Approximately one-fifth of dialysis unit resuscitations are not initiated until emergency medical service perso ...
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Journal ArticleJ Breast Imaging · May 17, 2025
We used focus groups of radiologists who led the implementation of contrast-enhanced mammography (CEM) in their practice to identify barriers and strategies for adoption. Members of the Society of Breast Imaging in the United States who served as lead on C ...
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Journal ArticleCHEST Crit Care · March 2025
BACKGROUND: Spiritual beliefs and spiritual support from clinicians can affect medical decision-making and coping during times of serious illness. RESEARCH QUESTION: How do religion and spirituality affect the critical illness experience of Black and White ...
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Journal ArticleJ Rural Health · March 2025
BACKGROUND: Rural adolescents in the United States lag behind their urban counterparts in the uptake of the human papillomavirus (HPV) vaccine. However, a systematic assessment of factors associated with rural-urban disparities in HPV vaccination coverage ...
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Journal ArticleJAMA Netw Open · January 2, 2025
IMPORTANCE: Health systems are increasingly required to conduct health-related social needs screening. However, how social resources negatively and positively affect recovery from acute illnesses, such as COVID-19, is incompletely understood. OBJECTIVE: To ...
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Journal ArticleJ Am Coll Radiol · January 2025
OBJECTIVE: This study explores radiology program directors' perspectives on the impact of large language model (LLM) use among residency applicants to craft personal statements. METHODS: Eight program directors from the Radiology Residency Education Resear ...
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Journal ArticleFront Public Health · 2025
INTRODUCTION: Smokeless tobacco (SLT) is significant public health problem in the U.S. and is associated with chronic diseases, which includes both physical and mental health conditions. Inequities in use exist as rural and other medically underserved popu ...
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Journal ArticleFront Public Health · 2025
INTRODUCTION: First Responders are three times more likely to use smokeless tobacco than those in the general population and very few targeted cessation interventions are available. METHODS: The #EnufSnuff.TXT First Responder text-based intervention (n = 3 ...
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Journal ArticleNicotine Tob Res · December 23, 2024
INTRODUCTION: Smokeless tobacco use remains prevalent in rural and medically underserved populations, leading to increased rates of tobacco-related cancers and chronic disease. While access to effective cessation programs is limited, text-based interventio ...
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Journal ArticleSupport Care Cancer · November 28, 2024
UNLABELLED: Hematopoietic cell transplantation (HCT) is a promising treatment for hematologic malignancies, but intensive conditioning leads to immunosuppression and susceptibility to healthcare-associated infections (HAI). Despite standard prevention meas ...
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Journal ArticleJ Am Geriatr Soc · August 2024
BACKGROUND: Central nervous system (CNS) medications are linked to higher morbidity and mortality in older adults. Hospitalization allows for deprescribing opportunities. This qualitative study investigates clinician and patient perspectives on CNS medicat ...
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Journal ArticleEur J Obstet Gynecol Reprod Biol · August 2024
BACKGROUND: Prior studies have shown that maternal deaths due to sepsis occur due to delays in recognition, treatment, and escalation of care through medical chart reviews. This study was conducted to obtain the patient perspective for near-miss and matern ...
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Journal ArticleJ Adolesc Young Adult Oncol · February 2024
Purpose: Adolescents and young adult (AYA) cancer survivors (15-39 years at diagnosis) are at risk for treatment-related late effects but face barriers in accessing survivorship care. We examined the prevalence of five health care access (HCA) barriers: af ...
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Journal ArticleAm J Hosp Palliat Care · January 2024
OBJECTIVES: Many cancer survivors experience chronic pain after completing curative-intent treatment. Based on available data, chronic pain may be undertreated in this context; however, little is known about cancer survivors' experiences with clinical mana ...
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Journal ArticleJAMA Surg · December 1, 2023
IMPORTANCE: Up to 40% of women experience dissatisfaction after breast reconstruction due to unexpected outcomes that are poorly aligned with personal preferences. Identifying what attributes patients value when considering surgery could improve shared dec ...
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Journal ArticlePrev Med Rep · December 2023
The purpose of this study, based in the United States, was to evaluate knowledge gaps and barriers related to diagnosis and care of inflammatory breast cancer (IBC), a rare but lethal breast cancer subtype, amongst Primary Care Providers (PCP) as they are ...
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Journal ArticleClin J Am Soc Nephrol · October 1, 2023
BACKGROUND: Potentially inappropriate medications, or medications that generally carry more risk of harm than benefit in older adults, are commonly prescribed to older adults receiving dialysis. Deprescribing, a systematic approach to reducing or stopping ...
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Journal ArticleAJPM Focus · September 2023
INTRODUCTION: This study describes changes in the mental health, financial security, and physical activity levels of women in North Carolina during the COVID-19 pandemic. METHODS: Data were collected from women aged 20-40 years receiving primary care at 2 ...
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Journal ArticleAm J Surg · April 2023
BACKGROUND: We sought to identify modifiable factors associated with cancer screening in a community-based health assessment. METHODS: 24 organizations at 47 community events in central North Carolina distributed a 91-item survey from April-December 2017. ...
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Journal ArticleJ Surg Res · April 2023
INTRODUCTION: We sought to examine patient and provider perspectives regarding modifiable contributors to breast cancer treatment and to assess perceptual alignment between these two groups. MATERIALS: Participants were women≥18 y with stage 0-IV breast ca ...
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Journal ArticleJCO Oncol Pract · April 2023
PURPOSE: Among cancer survivors who have completed curative-intent treatment, the high prevalence and adverse consequences of chronic pain are well documented. Yet, research on clinicians' experiences with and perspectives on managing chronic pain among ca ...
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Journal ArticleJ Am Coll Radiol · February 2023
OBJECTIVE: To understand how women and historically underrepresented minority medical students perceive radiology as a potential career choice. METHODS: Medical students representing a broad spectrum of radiology exposure from a single institution were inv ...
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Journal ArticleJ Ren Nutr · January 2023
OBJECTIVE: The Dietary Approaches to Stop Hypertension (DASH) eating plan improves hypertension in Black individuals and is associated with favorable chronic kidney disease (CKD) outcomes. Yet, adherence to DASH is low among US adults in general, particula ...
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Journal ArticleGynecol Oncol · January 2023
OBJECTIVES: Black patients with endometrial cancer are less likely to express distress and receive referrals for support services compared to White patients. We aim to characterize patient perceptions of the National Comprehensive Cancer Network Distress T ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · January 1, 2023
AbstractBackground: Although recognized as the most lethal breast cancer, inflammatory breast cancer (IBC), a NCI designated rare cancer and a cancer health disparity, is severely understudied. Given the uni ...
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Journal ArticleJ Clin Transl Sci · 2023
INTRODUCTION: The electronic health record (EHR) and patient portal are used increasingly for clinical research, including patient portal recruitment messaging (PPRM). Use of PPRM has grown rapidly; however, best practices are still developing. In this stu ...
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Journal ArticleCancers (Basel) · December 19, 2022
Several proposed theoretical frameworks have defined the complex nature of healthcare access (HCA) [...]. ...
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Journal ArticleHum Vaccin Immunother · November 30, 2022
The objective of this study was to identify factors at the individual, provider, and systems levels that serve as challenges or opportunities for increasing adolescent vaccination-including Human Papillomavirus (HPV) vaccination-in rural communities in the ...
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Journal ArticleBMJ Open · November 7, 2022
INTRODUCTION: Breast reconstruction plays an important role for many in restoring form and function of the breast after mastectomy. However, rates of breast reconstruction in the USA vary significantly by race, ethnicity and socioeconomic status. The lower ...
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Journal ArticleGynecol Oncol Rep · October 2022
OBJECTIVE: The online environment is an ideal setting to understand how many women seek, receive, and understand information about cancer treatment. The purpose of this study was to understand women's needs and information-seeking around Poly ADP ribose po ...
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Journal ArticleJournal of Trauma and Acute Care Surgery · October 2022
BACKGROUNDNoncompressible hemorrhage remains a high-mortality injury, which requires rapid damage control within minutes to avoid exsanguination. Retrievable stent grafts offer perfusion ...
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Journal ArticleVaccine X · August 2022
BACKGROUND AND OBJECTIVES: HPV vaccination coverage is lower than that of other adolescent vaccines in the southern US. This study sought to characterize caregiver attitudes associated with adolescent HPV vaccination in the southern US and to inform inter ...
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Journal ArticleAcad Radiol · July 2022
RATIONALE AND OBJECTIVES: Limited exposure to radiology by medical students can perpetuate negative stereotypes and hamper recruitment efforts. The purpose of this study is to understand medical students' perceptions of radiology and how they change based ...
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Journal ArticleMatern Child Health J · May 2022
INTRODUCTION: Smoking during pregnancy can affect infant birthweight. We tested whether an intervention that promoted scheduled gradual reduction improved birth outcomes among pregnant women who smoked. We also examined race differences in birth outcomes. ...
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Journal ArticleJ Am Med Inform Assoc · April 13, 2022
OBJECTIVE: To empirically explore how pragmatic clinical trials (PCTs) that used real-world data (RWD) assessed study-specific fitness-for-use. METHODS: We conducted interviews and surveys with PCT teams who used electronic health record (EHR) data to asce ...
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ConferenceBreast Cancer Res Treat · April 2022
PURPOSE: Patients diagnosed with ductal carcinoma in situ (DCIS) face trade-offs when deciding among different treatments, including surgery, radiation, and endocrine therapy. A less chosen option is active monitoring. While evidence from clinical trials i ...
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Journal ArticleJ Am Coll Surg · April 1, 2022
BACKGROUND: This prospective study was designed to compare quality of life (QoL) among patients who underwent open (O-PD) vs minimally invasive pancreaticoduodenectomy (MI-PD), using a combination of validated qualitative and quantitative methodologies. ST ...
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Journal ArticleAnn Surg Oncol · February 2022
BACKGROUND: Breast reconstruction is associated with improved patient well-being after mastectomy; however, factors that contribute to post-surgical dissatisfaction remain poorly characterized. METHODS: Adult women who underwent post-mastectomy implant-bas ...
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Journal ArticleMatern Child Health J · January 2022
OBJECTIVE: The purpose of this paper was to examine changes in situational temptations to smoke among women in early to late pregnancy enrolled in a texting trial to help them quit smoking. We compared changes between (1) intervention arms, (2) those who q ...
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Journal ArticlePalliat Med Rep · 2022
OBJECTIVE: Although skilled goals of care (GOC) conversations are known to reduce aggressive futile end-of-life care, they have not been widely implemented nor standardized in the care of gynecologic malignancies. Clinicians express concern regarding patie ...
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Journal ArticleVaccine · December 17, 2021
BACKGROUND AND OBJECTIVES: Despite a high burden of human papillomavirus (HPV)-attributable cancers, the southern US lags other regions in HPV vaccination coverage. This study sought to characterize and contextualize predictors of HPV vaccination in the so ...
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Journal ArticleBMJ Open · October 4, 2021
INTRODUCTION: Less than 40% of patients with ovarian cancer (OC) in the USA receive stage-appropriate guideline-adherent surgery and chemotherapy. Black patients with cancer report greater depression, pain and fatigue than white patients. Lack of access to ...
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Journal ArticleAm J Health Behav · September 30, 2021
Objectives: Understanding the relationship between human papillomavirus (HPV) knowledge and vaccination behavior is important to inform public health interventions, yet few validated HPV knowledge scales exist. This study describes development of the Human ...
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Journal ArticleJ Am Geriatr Soc · July 2021
BACKGROUND: Understanding the factors that influence hospital mobility, especially in the context of a heightened focus on falls prevention, is needed to improve care. OBJECTIVE: This qualitative study uses a socioecological framework to explore factors th ...
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Journal ArticleJCO Oncol Pract · June 2021
PURPOSE: Although financial toxicity is a well-documented aspect of cancer care, little is known about how patients narratively characterize financial experiences related to breast cancer treatment. We sought to examine these patient experiences through mi ...
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Journal ArticlePrev Med Rep · June 2021
OBJECTIVE: Guidelines informing screening mammography for older women are lacking. This study sought to characterize PCP perspectives on screening mammography for patients aged 75 and older. METHODS: This was an exploratory, qualitative study based on semi ...
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Journal ArticleAddict Behav · March 2021
INTRODUCTION: Light smoking (smoking ≤ 10 cigarettes per day or on some days) has become increasingly prevalent in the US and increases morbidity and mortality. Many light smokers do not experience significant nicotine withdrawal but instead smoke in respo ...
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Journal ArticleTransplant Cell Ther · February 2021
Hematopoietic stem cell transplantation (HCT) is a curative treatment option for patients with hematologic conditions but presents many complications that must be managed as a complex, chronic condition. Mobile health applications (mHealth apps) may permit ...
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Journal ArticleProg Community Health Partnersh · 2021
The connection between health and housing is well-established. People who are precariously housed have worse health than those who have stable housing arrangements.- Persons moving into public housing have a higher illness burden than the general populatio ...
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Journal ArticleObstet Gynecol · December 2020
INTRODUCTION: To gain a better understanding of gynecologic oncology patient adherence to oral anticancer agents through both a cross-sectional survey of adherence and qualitative interviews with patients and clinicians regarding their experience with thes ...
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Journal ArticleAddict Behav · September 2020
INTRODUCTION: Smokeless tobacco (ST) use significantly affects morbidity and mortality and remains disproportionally prevalent in rural and medically underserved communities. Few programs exist for rural smokeless tobacco users. Text-based interventions ma ...
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Journal ArticleNicotine Tob Res · June 12, 2020
INTRODUCTION: Smoking during pregnancy poses serious risks to baby and mother. Few disseminable programs exist to help pregnant women quit or reduce their smoking. We hypothesized that an SMS text-delivered scheduled gradual reduction (SGR) program plus su ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · June 1, 2020
AbstractIntroduction: Inflammatory breast cancer (IBC) is a rare but the most lethal breast cancer often misdiagnosed as mastitis or dermatitis since majority of cases lack a clinically apparent tumor mass a ...
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ConferenceJ Vasc Surg · June 2020
OBJECTIVE: Previously, we described a Vascular Study Group of New England (VSGNE) risk predictive model to predict composite adverse outcomes (postoperative death, stroke, myocardial infarction, or discharge to extended care facilities) after carotid endar ...
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Journal ArticleJ Vasc Access · May 2020
BACKGROUND: Arteriovenous fistula is the ideal hemodialysis access, but most patients start with tunneled dialysis catheter. Arteriovenous fistula and arteriovenous graft surgery may reduce tunneled dialysis catheter use and also increase procedural expens ...
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Journal ArticleMatern Child Health J · April 2020
INTRODUCTION: Most pregnant women know that smoking poses serious risks to baby and mother, yet many still smoke. We conducted a large randomized controlled trial and found that an SMS text-delivered program helped about 10% of these women quit smoking. In ...
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Journal ArticleCancer · March 1, 2020
BACKGROUND: Engaging diverse populations in biomedical research, including biospecimen donation, remains a national challenge. This study examined factors associated with an invitation to participate in biomedical research, intent to participate in biomedi ...
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Journal ArticleJournal of Smoking Cessation · March 2020
AbstractIntroductionLight and intermittent smokers (LITS) represent almost 50% of all current smokers. Research is needed to understand smoki ...
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Chapter · 2020
Achieving cancer health equity is a national imperative. Cancer is the second leading cause of death in the United States and in North Carolina (NC), where the disease disproportionately impacts traditionally underrepresented race and ethnic groups, those ...
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Journal ArticleKidney Med · 2020
RATIONALE & OBJECTIVE: Attention to geriatric impairments is not routinely provided to older adults receiving dialysis. Our objective was to identify patient and personnel perspectives on experiences with geriatric problems, unmet needs that may affect a p ...
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Journal ArticleNephrol Nurs J · 2020
Cardiac arrest is the leading cause of death among patients receiving hemodialysis, and major deficiencies exist in hemodialysis staff-provided cardiopulmonary resuscitation (CPR). Our study aimed to identify factors influencing CPR delivery in the outpati ...
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Journal ArticleAddict Behav · November 2019
BACKGROUND: Most clinical and laboratory smoking research studies require that participants smoke at a certain level to be eligible for enrollment. However, there is limited evidence that use of these cutoffs differentiates groups of smokers along clinical ...
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ConferenceAnn Surg Oncol · October 2019
BACKGROUND: Cancer treatment costs are not routinely addressed in shared decisions for breast cancer surgery. Thus, we sought to characterize cost awareness and communication among surgeons treating breast cancer. METHODS: We conducted a self-administered, ...
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Journal ArticleJ Oncol Pract · August 2019
PURPOSE: Financial toxicity is a well-recognized adverse effect of cancer care, yet little is known about how women consider treatment costs when facing preference-sensitive decisions for breast cancer surgery or how surgical treatment choice affects finan ...
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Journal ArticleJ Med Chem · June 27, 2019
Lysyl oxidase (LOX) is a secreted copper-dependent amine oxidase that cross-links collagens and elastin in the extracellular matrix and is a critical mediator of tumor growth and metastatic spread. LOX is a target for cancer therapy, and thus the search fo ...
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Journal ArticleEur J Vasc Endovasc Surg · February 2019
OBJECTIVES: End stage renal disease (ESRD) patients with peripheral arterial disease (PAD) are at high risk of complications following open surgical revascularisation (OSR). Endovascular revascularisation (ER) is an option, but its role is unclear. This st ...
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Journal ArticleJ Cancer Surviv · December 2018
PURPOSE: Many cancer survivors continue to smoke. Further, most survivors also report high levels of persistent pain and smoke in response to pain. The investigators tested the feasibility, acceptability, and preliminary efficacy of a smoking cessation pro ...
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Journal ArticleUrol Oncol · November 2018
PURPOSE: In response to controversy regarding prostate cancer (CaP) screening recommendations, a consolidated Duke Cancer Institute (DCI) multidisciplinary algorithm for CaP screening was developed and implemented. We conducted an online survey within the ...
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ConferenceJournal of Clinical Oncology · October 20, 2018
207 Background: Despite the recognized side effect of financial toxicity after cancer, treatment decisions for breast cancer rarely include the costs of care. We sought to determine women’s experiences with breast cancer treatmen ...
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Journal ArticleFam Process · September 2018
Many couples tend to report steadily decreasing relationship quality following the birth of a child. However, little is known about the postpartum period for Latino couples, a rapidly growing ethnic group who are notably underserved by mental and physical ...
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Journal ArticleJ Pain Symptom Manage · August 2018
CONTEXT: Couple-based communication interventions have beneficial effects for patients with cancer and their partners. However, few studies have targeted patients with advanced stages of disease, and little is known about how best to assist couples in disc ...
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Journal ArticleJ Vasc Surg Venous Lymphat Disord · July 2018
OBJECTIVE: During the past few years, there has been a surge in the use of catheter-directed thrombolysis (CDT) for acute pulmonary embolism (PE), in the form of either standard CDT or ultrasound-assisted CDT (usCDT). This is a systematic review and meta-a ...
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Journal ArticleHealth Educ Res · February 1, 2018
Text-based interventions are effective for smoking cessation, but have not been tested in rural older adults. The purpose of this study was to compare the feasibility, acceptability and preliminary efficacy of a text-based Scheduled Gradual Reduction (SGR) ...
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Journal ArticleJ Clin Transl Sci · February 2018
INTRODUCTION: The Duke Multidisciplinary Education and Research in Translational Sciences Program provides educational resources for faculty and trainees in translational research. METHODS: To aid in program development, we assessed perceptions of translat ...
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Journal ArticleJ Vasc Surg Venous Lymphat Disord · January 2018
BACKGROUND: Catheter-directed interventions for the treatment of patients with submassive pulmonary embolism (sPE) have shown promise in rapidly improving right-sided heart strain and preventing decompensation to massive pulmonary embolism. Among various c ...
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ConferenceJ Vasc Surg · January 2018
OBJECTIVE: In addition to age and comorbidities, health-related quality of life (HRQOL) is known to predict mortality in hemodialysis (HD) patients. Understanding the association of vascular access type with HRQOL can help surgeons to provide patient-cente ...
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ConferencePsychooncology · December 2017
BACKGROUND: Patients with acute myeloid leukemia (AML) face a unique, difficult situation characterized by sudden changes in health, complex information, and pressure to make quick treatment decisions amid sizeable tradeoffs. Yet, little is known about pat ...
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ConferenceJ Vasc Surg · February 2017
OBJECTIVE: Postoperative respiratory adverse events (RAEs) are associated with high rates of morbidity and mortality in general surgery, however, little is known about these complications in the vascular surgery population, a frail subset with multiple com ...
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Journal ArticleInternational Social Work · November 2016
Young children ( N = 381) from three institutions in St Petersburg (Russian Federation) who were transitioned to intercountry (USA) adoption or to various domestic families in Russia did not differ in birth weight, length, head circumference, and r ...
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ConferenceJournal of Clinical Oncology · October 9, 2016
233 Background: Interventions to enhance couples’ communication about cancer-related issues can lead to benefits for patients, spouses, and their relationships. We recently conducted a pilot study testing a couples communication ...
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Journal ArticleNicotine Tob Res · October 2016
INTRODUCTION: Most pregnant women who quit smoking return to smoking postpartum. Trials to prevent this return have been unsuccessful. We tested the efficacy of a nurse-delivered intervention in maintaining smoking abstinence after delivery among pregnant ...
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Journal ArticleAnn Behav Med · August 2016
BACKGROUND: Research suggests that when smokers reduce their smoking, they also reduce their alcohol consumption. PURPOSE: To examine the effects of a smoking cessation intervention and actual quitting smoking on binge drinking behavior among Latino expect ...
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Journal ArticleJ Health Psychol · June 2016
The purpose of this study was to test an intervention to increase mammography screening in women 51-75 years of age who had not received a mammogram in the last 15 months. A total of 1681 women were randomized to (1) a mailed tailored interactive DVD, (2) ...
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Journal ArticleJ Pain Symptom Manage · December 2015
CONTEXT: Prior cross-sectional studies have reported greater pain intensity among persistent smokers compared with nonsmokers or former smokers; yet, few prospective studies have examined how smoking abstinence affects pain intensity. OBJECTIVES: To determ ...
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Journal ArticleHealth Psychol · October 2015
OBJECTIVE: Cigarette smoking is a prevalent problem among Latinos, yet little is known about what factors motivate them to quit smoking or make them feel more confident that they can. Given cultural emphases on familial bonds among Latinos (e.g., familismo ...
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Journal ArticleAnn Vasc Surg · August 2015
BACKGROUND: Long-term atherosclerotic adverse events are anticipated in patients undergoing carotid endarterectomy (CEA); however, their incidence and risk predictors remain unknown. METHODS: A consecutive cohort of CEAs between 1/1/2000-12/31/2007 was ana ...
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Journal ArticleJ Vasc Surg · July 2015
OBJECTIVE: Arteriovenous fistulas (AVFs) are associated with improved long-term outcomes but longer maturation times and higher primary failure rates compared with arteriovenous grafts (AVGs). The Fistula First Breakthrough Initiative has recently emphasiz ...
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Journal ArticleNicotine Tob Res · June 2015
INTRODUCTION: Although many pregnant women quit smoking, most return to smoking postpartum. Returning to smoking is strongly related to women's stated intention about smoking during pregnancy. We examined factors related to women's intention to return to s ...
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ConferenceJ Vasc Surg · June 2015
OBJECTIVE: The treatment outcomes of ruptured visceral artery aneurysms (rVAAs) have been sparsely characterized, with no clear comparison between different treatment modalities. The purpose of this paper was to review the perioperative and long-term outco ...
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Journal ArticleNicotine Tob Res · May 2015
INTRODUCTION: An increasing proportion of daily smokers are light smokers (≤10 cigarettes per day). Some light smokers have never smoked more than 10 cigarettes per day (native light smokers) and others smoked at higher levels but have cut down (converted ...
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Journal ArticleCancer Epidemiol Biomarkers Prev · February 2015
BACKGROUND: Although many Latinos in the United States smoke, they receive assistance to quit less often than non-Latinos. To address this disparity, we recruited Latino couples into a randomized controlled trial and provided a smoking cessation program du ...
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Journal ArticleCancer Cell · January 12, 2015
BRAF and MEK inhibitors are effective in BRAF mutant melanoma, but most patients eventually relapse with acquired resistance, and others present intrinsic resistance to these drugs. Resistance is often mediated by pathway reactivation through receptor tyro ...
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Journal ArticleMedChemComm · 2015
The tankyrase proteins (TNKS, TNKS2) are attractive anti-cancer drug targets, particularly as inhibition of their catalytic activity has been shown to antagonise oncogenic WNT signalling. ...
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ConferenceCancer Research · October 1, 2014
AbstractThe protein kinase BRAF is mutated ∼40% of human melanomas. BRAF is a component of the RAS/RAF/MEK/ERK pathway and BRAF or MEK inhibitors increase progression-free and overall survival in melanoma pa ...
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Journal ArticleNicotine Tob Res · October 2013
INTRODUCTION: Smoking during pregnancy causes multiple perinatal complications; yet, the smoking rate among pregnant women has remained relatively stagnant. Most interventions to help pregnant smokers quit or reduce their smoking are not easily disseminabl ...
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Journal ArticleAm J Health Educ · 2013
BACKGROUND: Understanding the gaps in knowledge about human papilloma virus (HPV) infection, transmission, and health consequences and factors associated with the knowledge gap is an essential first step for the development of interventions to improve adhe ...
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Journal ArticleChild Dev · 2013
This article reports the maintenance of one of the largest interventions conducted in St. Petersburg (Russian Federation) orphanages for children birth to 4 years using regular caregiving staff. One orphanage received training plus structural changes, anot ...
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Journal ArticleAm J Health Promot · 2013
PURPOSE: When a patient is diagnosed with lung cancer, members of his/her social network may be more likely to engage in smoking cessation efforts. Proactive telephone counseling combined with a tailored self-directed intervention may be more effective at ...
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Journal ArticleAddict Behav · January 2012
Featured Publication
OBJECTIVE: To examine demographic, relationship, and smoking history factors related to expected positive and negative support for quitting smoking among chronically ill veterans. METHODS: Data for this report comes from baseline data from a randomized con ...
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Journal ArticleMol Biol Cell · September 2011
Genetic screens in Drosophila have identified regulators of endocytic trafficking as neoplastic tumor suppressor genes. For example, Drosophila endosomal sorting complex required for transport (ESCRT) mutants lose epithelial polarity and show increased cel ...
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Journal ArticleContemp Clin Trials · July 2011
Featured Publication
BACKGROUND: This report describes the characteristics associated with successful enrollment of smokers in the social networks (i.e., family and close friends) of patients with lung cancer into a smoking cessation intervention. METHODS: Lung cancer patients ...
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Journal ArticleInfant Ment Health J · March 2011
This study provides descriptive empirical information on the environments, organizational structure, caregivers, caregiver-child interactions, and children's general behavioral development and problem behaviors from three institutions for young children in ...
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Journal Article · December 1, 2010
This chapter addresses the problem of adherence to smoking cessation. Several types of interventions targeting smokers have been successful at promoting cessation. In this review, we will provide examples of successful interventions for primary and seconda ...
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Journal ArticleInfant Ment Health J · September 2010
A pilot intervention that emphasized training and technical assistance to promote warm, sensitive, and responsive one-on-one caregiver-child interactions primarily during feeding and bathing/changing was implemented using regular staff in a depressed orpha ...
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Journal ArticleInfant Mental Health Journal · March 2010
AbstractThis article reports the construction and pilot reliability, validity, and psychometric properties of a new caregiver–child rating scale that emphasizes caregiver–child socioemotional interactions and relationships. ...
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Journal ArticleEthn Health · 2010
Featured Publication
OBJECTIVE: Pregnancy may be a time when US Latino expectant fathers consider quitting smoking. A 'teachable moment' is theorized to increase motivation to change a behavior through increased risk perceptions, emotional responses, and changes in self-image. ...
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Journal ArticleEthnicity & health · December 2009
Objective. Pregnancy may be a time when US Latino expectant fathers consider quitting smoking. A 'teachable moment' is theorized to increase motivation to change a behavior through increased risk perceptions, emotional responses, and changes in self-image. ...
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Journal ArticleAm J Obstet Gynecol · October 2009
Featured Publication
OBJECTIVE: The purpose of this study was to determine the contribution of randomization to nicotine replacement therapy (NRT), sociodemographic and psychosocial factors, and pregnancy and medical history to serious perinatal adverse events among pregnant s ...
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Journal ArticleNicotine Tob Res · May 2009
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INTRODUCTION: This secondary analysis examined the association between adherence to nicotine replacement therapy (NRT) and smoking cessation among pregnant smokers enrolled in Baby Steps, an open-label randomized controlled trial testing cognitive-behavior ...
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Journal ArticleCommunity Genet · 2008
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This study explored whether reactions to the Cancer Genetics Network (CGN) or CGN enrollment differed by receipt of a standard informational brochure versus a targeted version addressing factors previously associated with African Americans' health behavior ...
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Journal ArticleAm J Prev Med · October 2007
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BACKGROUND: This study examines whether adding nicotine replacement therapy (NRT) to cognitive-behavioral therapy (CBT) for pregnant smokers increases rates of smoking cessation. METHODS: An open-label randomized trial (Baby Steps, n=181) of CBT-only versu ...
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Journal ArticleNicotine Tob Res · August 2006
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Improvements in smoking cessation interventions for pregnant smokers are needed. One major step is to examine the potential effectiveness of nicotine replacement therapy (NRT). The potential benefits of providing pregnant women with NRT to help them quit s ...
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Journal ArticlePharmacoepidemiol Drug Saf · December 2005
PURPOSE: Recent research suggests that letters to healthcare providers may not effectively communicate safety-related information. This study examined whether content, organization, and formatting of dear doctor letters (DDLs) influences physicians' respon ...
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Journal ArticleAm J Clin Oncol · December 2005
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OBJECTIVES: Prospective assessment of the informational needs of radiation oncology patients and efficacy of an educational video in meeting them. METHODS: Subjects completed baseline self-administered questionnaires and subsequently viewed the patient edu ...
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Journal ArticleJ Behav Med · February 2005
Factors related to initiation and discontinuation of hormonal therapy (HT) for treatment of menopausal symptoms were examined in a community sample of 533 peri/postmenopausal women aged 45-54 by telephone three times. Over 40 variables including: sociodemo ...
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Journal ArticleAm J Health Behav · 2005
OBJECTIVE: To evaluate the effectiveness of a smoking cessation intervention based on the transtheoretical model of change with a sample of low-income African American smokers admitted to an indigent-care hospital. METHODS: The intervention incorporated co ...
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Journal ArticleAm J Health Behav · 2004
OBJECTIVE: To examine predicted relationships among transtheoretical model of change measures in a sample of 211 low-income, African American hospitalized smokers. METHODS: We used discriminant analysis to examine differences in decisional balance and self ...
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Journal ArticlePrev Med · August 2003
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OBJECTIVES: Sexually transmitted diseases (STD) research has focused on high-risk populations such as STD clinic patients and college students. This report examines predictors of unprotected sex among nonstudent women seen in primary care. STUDY DESIGN: Da ...
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Journal ArticleAIDS · July 4, 2003
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OBJECTIVE: To evaluate the efficacy of a theory-based tailored minimal self-help intervention to increase condom use among young women at risk for HIV/sexually transmitted disease (STD). DESIGN: Randomized controlled trial on an intent-to-treat basis in tw ...
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Journal ArticleCancer · March 15, 2003
BACKGROUND: African-American patients have been under-represented in oncology clinical trials. Better understanding barriers to African-American participation may help increase the accrual of African-American patients onto clinical trials. METHODS: Two hun ...
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Journal ArticleJ Cancer Educ · 2003
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BACKGROUND: Heightened distress at the time of a loved one's lung cancer diagnosis may motivate relatives to quit smoking or could undermine cessation. METHODS: Relatives of new lung cancer patients at Duke were surveyed by telephone to assess diagnosis-re ...
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Journal ArticleAIDS Care · December 2002
Condoms must be used effectively in order to prevent pregnancy and the spread of HIV/STD. This study investigated two types of ineffective condom use, delayed condom use (initiated after penetration has occurred) and condom slippage and/or breakage. We est ...
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Journal ArticlePatient Educ Couns · December 2002
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BACKGROUND: Associations between optimal use of a tailored decision-aid and levels of accuracy of perceived breast cancer risk, confidence in decision-making, and satisfaction with decisions about HRT were evaluated in a randomized intervention trial with ...
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Journal ArticleHealth Psychol · November 2002
From a biomedical perspective, variations in the quality of life of chronic obstructive pulmonary disease (COPD) patients may be attributed to changes in pulmonary function; thus, an increase in lung function should be correlated with an increased score on ...
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Journal ArticlePain · July 2002
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This study examined the degree of correspondence between lung cancer patients and their family caregivers in their perceptions of the patients' self-efficacy for managing pain and other symptoms of lung cancer, and the association of this correspondence to ...
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Journal ArticleJ Health Popul Nutr · March 2002
This retrospective study examined duration of breast-feeding and concurrent contraceptive use among 5,648 Peruvian women. Data were gathered during 1986-1992 as part of the Demographic and Health Survey (DHS). The women gave birth to 7,951 infants, 95% of ...
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Journal ArticleJ Cancer Educ · 2002
Description. From 1988 through September 2001 the Cancer Prevention and Control Training Program at the University of Alabama at Birmingham has supported 52 pre- and postdoctoral trainees in Public Health disciplines, with 31% of the trainees members of mi ...
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Journal ArticleAnn Allergy Asthma Immunol · June 2001
OBJECTIVE: This article presents information on the important impact the lack of adherence to prescribed treatments has on the morbidity and mortality of asthma. After reading this article, readers should have an understanding of the significant role clini ...
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Journal ArticleCancer Epidemiol Biomarkers Prev · September 2000
When trying to predict breast cancer screening, it may be important to understand the relationships between perceived breast cancer risks and worries about getting breast cancer. This study examines the extent to which women's worries about breast cancer c ...
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Journal ArticleJ Cancer Educ · 2000
The pre- and postdoctoral Cancer Prevention and Control Training Program (CPCTP) at the University of Alabama at Birmingham (UAB) has attracted high-quality trainees from all over the United States. The trainees have pursued courses of study in epidemiolog ...
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Journal ArticleJ Cancer Educ · 2000
To address the shortage of health care professionals trained in the nutritional aspects of cancer prevention, the University of Alabama at Birmingham in 1988 initiated the Cancer Prevention and Control Training Program (CPCTP), with R25 grant support from ...
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Journal ArticleJAMA · January 6, 1999
CONTEXT: Antenatal corticosteroids for fetal maturation have been underused, despite evidence for their benefits in cases of preterm birth. OBJECTIVE: To evaluate dissemination strategies aimed at increasing appropriate use of this therapy. DESIGN AND SETT ...
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Journal ArticleAnn Allergy Asthma Immunol · May 1998
BACKGROUND: National and international guidelines recommend inhaled anti-inflammatory medications for patients with all but the mildest forms of asthma. Patients may also be more compliant with twice daily dosing. OBJECTIVE: To evaluate the efficacy and sa ...
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Journal ArticleAm J Public Health · February 1996
We studied smoking status in relation to parental attendance at an asthma education program for child patients of a health maintenance organization. Nonattendance rates were 24%, 42%, and 78% in nonsmoking, one-smoker, and two-or-more-smoker families, resp ...
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Journal ArticleJ Asthma · 1996
A randomized control trial of the Wee Wheezers asthma education program was conducted with 76 children < 7 years of age, 31% of whom were on a medication regimen consistent with mild, 51% with moderate, and 18% with moderately severe/severe asthma. Treatme ...
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Journal ArticleJournal of Social Issues · April 1994
While empirical studies have generally demonstrated the value of mediation in divorce, little research has been conducted on the specific models of mediation that are most efficacious in such disputes. This article reports the results ...
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Journal ArticleJ Pediatr Psychol · February 1993
To define the specific objectives of a planned behavioral intervention directed toward parents of very young children with asthma, 574 detailed descriptions of ineffective and effective asthma management behaviors of parents of infants and young children ( ...
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Journal ArticleJ Neurochem · July 1990
Alternative splicing of the transcript encoding the beta-amyloid precursor protein (BAPP) of Alzheimer's disease produces multiple mRNA species. Translation of these mRNAs predicts protein products of 770, 751, and 695 amino acids. The difference arises fr ...
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