Scholars@Duke
Momen Mohammed Wahidi

Momen Mohammed Wahidi

Adjunct Professor in the Department of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
momen.wahidi@duke.edu
Duke Box 102356, Durham, NC 27710
Dept of Medicine, Durham, NC 27710

Selected Publications

The 2023 American Association for Thoracic Surgery (AATS) Expert Consensus Document: Management of subsolid lung nodules.

Journal Article J Thorac Cardiovasc Surg · September 2024 OBJECTIVE: Lung cancers that present as radiographic subsolid nodules represent a subtype with distinct biological behavior and outcomes. The objective of this document is to review the existing literature and report consensus among a group of multidiscipl ... Full text Link to item Cite

Navigational Bronchoscopy vs CT Scan-Guided Transthoracic Needle Biopsy for the Diagnosis of Indeterminate Lung Nodules: Protocol and Rationale for the Navigation Endoscopy to Reach Indeterminate Lung Nodules vs Transthoracic Needle Aspiration, a Randomized Controlled Study Multicenter Randomized Trial

Journal Article CHEST Pulmonary · September 1, 2024 Background: Lung nodule incidence is increasing. Many nodules require biopsy to discriminate between benign and malignant causes. The gold standard for minimally invasive biopsy, CT scan-guided transthoracic needle biopsy (CT-TTNB), has not been compared d ... Full text Cite

Differences in microenvironment of lung cancer and pleural effusions by single-cell RNA sequencing.

Journal Article Lung Cancer · July 2024 BACKGROUND: Direct comparison of tumor microenvironment of matched lung cancer biopsies and pleural effusions (PE) from the same patients is critical in understanding tumor biology but has not been performed. This is the first study to compare the lung can ... Full text Link to item Cite

A Nasal Swab Classifier to Evaluate the Probability of Lung Cancer in Patients With Pulmonary Nodules.

Journal Article Chest · April 2024 BACKGROUND: Accurate assessment of the probability of lung cancer (pCA) is critical in patients with pulmonary nodules (PNs) to help guide decision-making. We sought to validate a clinical-genomic classifier developed using whole-transcriptome sequencing o ... Full text Link to item Cite

Effectiveness and Safety of Argon Plasma Coagulation in Patients with Haemoptysis Caused by an Endobronchial Malignancy.

Journal Article Respiration · 2024 INTRODUCTION: Patients with central neoplasms and haemoptysis show low survival rates. Symptom control without recurrence 48 h after bronchoscopic interventions may improve the prognosis of these patients. Bronchoscopic argon plasma coagulation (APC) is a ... Full text Link to item Cite

Navigational Bronchoscopy versus Computed Tomography-guided Transthoracic Needle Biopsy for the Diagnosis of Indeterminate Lung Nodules: protocol and rationale for the VERITAS multicenter randomized trial.

Journal Article medRxiv · November 23, 2023 BACKGROUND: Lung nodule incidence is increasing. Many nodules require biopsy to discriminate between benign and malignant etiologies. The gold-standard for minimally invasive biopsy, computed tomography-guided transthoracic needle biopsy (CT-TTNB), has nev ... Full text Link to item Cite

A Multicenter, Single-Arm, Prospective Trial Assessing the Diagnostic Yield of Electromagnetic Bronchoscopic and Transthoracic Navigation for Peripheral Pulmonary Nodules.

Journal Article Am J Respir Crit Care Med · October 15, 2023 Rationale: Strict adherence to procedural protocols and diagnostic definitions is critical to understand the efficacy of new technologies. Electromagnetic navigational bronchoscopy (ENB) for lung nodule biopsy has been used for decades without a solid unde ... Full text Link to item Cite

High Yield of Pleural Cell-Free DNA for Diagnosis of Oncogenic Mutations in Lung Adenocarcinoma.

Journal Article Chest · July 2023 BACKGROUND: Pleural cytology is currently used to assess targetable mutations in patients with advanced lung adenocarcinoma. However, it is fraught with low diagnostic yield. RESEARCH QUESTION: Can pleural cell-free DNA (cfDNA) be used to assess targetable ... Full text Link to item Cite

Value-Based Care for Chest Physicians.

Journal Article Chest · May 2023 Value-based care aims to improve the health outcomes of patients, eliminate waste and unwarranted clinical variation, and reduce the total cost of care. Professional medical societies have put forward guidelines to raise awareness on unproven practice patt ... Full text Link to item Cite

Bronchoalveolar Lavage (BAL) and Pathologic Assessment of Electronic Cigarette or Vaping Product Use-associated Lung Injury (EVALI): The EVALI-BAL Study, A Multicenter Cohort.

Journal Article J Bronchology Interv Pulmonol · April 1, 2023 BACKGROUND: E-cigarette or vaping-use related acute lung injury (EVALI) is a spectrum of radiographic and histologic patterns consistent with acute to subacute lung injury. However, limited data exist characterizing bronchoalveolar lavage (BAL) findings. T ... Full text Link to item Cite

Interventional Pulmonology Productivity, Compensation, and Practice Benchmarks: The AABIP 2022 Report.

Journal Article J Bronchology Interv Pulmonol · April 1, 2023 BACKGROUND: Interventional pulmonology (IP) is a growing field that has not yet been recognized by the American Board of Medical Specialties or incorporated into national benchmark organizations. As a result, there is a lack of data on IP practice patterns ... Full text Link to item Cite

Bronchoscopic Evaluation of a Steerable Needle for Simulated Tumor Targets in the Lung Periphery: A Feasibility Study (Bullseye).

Journal Article Respiration · 2023 BACKGROUND: Peripheral bronchoscopy is often performed to biopsy peripheral pulmonary lesions. Despite technological advancements to improve reach and access to the lung periphery, the diagnostic yield of peripheral bronchoscopy has been inconsistent, and ... Full text Link to item Cite

Sampling of Thoracic Lymph Nodes and Lung Lesions: Trends in Procedural Utilization.

Journal Article Respiration · 2023 BACKGROUND: Advances in bronchoscopy have impacted the practice patterns in the sampling of thoracic lymph nodes and lung lesions. OBJECTIVES: The aim of the study was to study the trends in utilization of mediastinoscopy, transthoracic needle aspiration ( ... Full text Link to item Cite

Bleeding Risk With Combination Intrapleural Fibrinolytic and Enzyme Therapy in Pleural Infection: An International, Multicenter, Retrospective Cohort Study.

Journal Article Chest · December 2022 BACKGROUND: Combination intrapleural fibrinolytic and enzyme therapy (IET) has been established as a therapeutic option in pleural infection. Despite demonstrated efficacy, studies specifically designed and adequately powered to address complications are s ... Full text Link to item Cite

Silver Nitrate-coated versus Standard Indwelling Pleural Catheter for Malignant Effusions: The SWIFT Randomized Trial.

Journal Article Ann Am Thorac Soc · October 2022 Rationale: Tunneled, indwelling pleural catheters (IPCs) have been demonstrated to be an effective method of managing malignant pleural effusions. However, they allow pleurodesis and can therefore be removed in only a subset of patients. A novel, silver ni ... Full text Link to item Cite

A Direct Comparative Study of Bronchoscopic Navigation Planning Platforms for Peripheral Lung Navigation: The ATLAS Study.

Conference J Bronchology Interv Pulmonol · July 1, 2022 BACKGROUND: The use of mapping to guide peripheral lung navigation (PLN) represents an advance in the management of peripheral pulmonary lesions (PPL). Software has been developed to virtually reconstruct computed tomography images into 3-dimensional airwa ... Full text Link to item Cite

Meta-analysis and Systematic Review of Bronchoscopic Lung Volume Reduction Through Endobronchial Valves in Severe Emphysema.

Journal Article J Bronchology Interv Pulmonol · July 1, 2022 BACKGROUND: Pharmacologic therapeutics for advanced emphysema have limited benefit. Bronchoscopic lung volume reduction with endobronchial valves (EBVs) have reported improvements in lung function, breathlessness, and quality of life through randomized cli ... Full text Link to item Cite

Efficacy and safety of virtual bronchoscopic navigation with fused fluoroscopy and vessel mapping for access of pulmonary lesions.

Journal Article Respirology · May 2022 BACKGROUND AND OBJECTIVE: Virtual bronchoscopic navigation (VBN) with fused fluoroscopy and vessel mapping provides a point of entry (POE) for puncturing airway wall to biopsy lesions. The study was designed to evaluate the safety and efficacy of this tech ... Full text Link to item Cite

Bronchial Thermoplasty in Patients With Severe Asthma at 5 Years: The Post-FDA Approval Clinical Trial Evaluating Bronchial Thermoplasty in Severe Persistent Asthma Study.

Journal Article Chest · March 2022 BACKGROUND: Bronchial thermoplasty is a device-based treatment for subjects ≥ 18 years of age with severe asthma poorly controlled with inhaled corticosteroids and long-acting beta-agonists. The Post-FDA Approval Clinical Trial Evaluating Bronchial Thermop ... Full text Link to item Cite

Comparison of Forceps, Cryoprobe, and Thoracoscopic Lung Biopsy for the Diagnosis of Interstitial Lung Disease - The CHILL Study.

Journal Article Respiration · 2022 RATIONALE: Transbronchial lung cryobiopsy (TBLC) has emerged as a less invasive method to obtain a tissue diagnosis in patients with interstitial lung disease (ILD). The diagnostic yield of TBLC compared to surgical lung biopsy (SLB) remains uncertain. OBJ ... Full text Link to item Cite

Accuracy of Pulmonary Nodule Sampling Using Robotic Assisted Bronchoscopy with Shape Sensing, Fluoroscopy, and Radial Endobronchial Ultrasound (The ACCURACY Study).

Journal Article Respiration · 2022 BACKGROUND: Despite recent advances in guided bronchoscopy, the yield of bronchoscopic biopsy of a peripheral pulmonary nodule (PPN) remains highly variable. OBJECTIVE: The aim of the study was to evaluate which features of robotic assisted bronchoscopy (R ... Full text Link to item Cite

Clinical validation and utility of Percepta GSC for the evaluation of lung cancer.

Journal Article PLoS One · 2022 The Percepta Genomic Sequencing Classifier (GSC) was developed to up-classify as well as down-classify the risk of malignancy for lung lesions when bronchoscopy is non-diagnostic. We evaluated the performance of Percepta GSC in risk re-classification of in ... Full text Link to item Cite

Use of fibrinolytics and deoxyribonuclease in adult patients with pleural empyema: a consensus statement.

Journal Article Lancet Respir Med · September 2021 Although our understanding of the pathogenesis of empyema has grown tremendously over the past few decades, questions still remain on how to optimally manage this condition. It has been almost a decade since the publication of the MIST2 trial, but there is ... Full text Link to item Cite

Pilot Study of the Performance of 19-G Needle in Endobronchial Ultrasound-guided Transbronchial Aspiration for the Diagnosis and Testing of Molecular Markers in Lung Cancer.

Journal Article J Bronchology Interv Pulmonol · July 1, 2021 BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become the standard for diagnosis and staging of lung cancer. Historically, 21- and 22-G needles have been paired with EBUS. We evaluated the performance of EBUS-T ... Full text Link to item Cite

Advanced Diagnostic and Therapeutic Bronchoscopy: Technology and Reimbursement.

Journal Article Chest · July 2021 Advanced interventional pulmonary procedures of the airways, pleural space, and mediastinum continue to evolve and be refined. Health care, finance, and clinical professionals are challenged by both the indications and related coding complexities. As the s ... Full text Link to item Cite

Detection of actionable molecular alterations through combined DNA/RNA molecular profiling of biopsies collected in early-stage lung cancer at time of diagnosis.

Conference Journal of Clinical Oncology · May 20, 2021 e20546 Background: Significant progress has been made in improving progression-free survival in lung cancer through the combination of molecular biomarker testing and personalized therapeutics. Broadening access to national guide ... Full text Cite

Association between Tunneled Pleural Catheter Use and Infection in Patients Immunosuppressed from Antineoplastic Therapy. A Multicenter Study.

Journal Article Ann Am Thorac Soc · April 2021 Rationale: Patients with malignant or paramalignant pleural effusions (MPEs or PMPEs) may have tunneled pleural catheter (TPC) management withheld because of infection concerns from immunosuppression associated with antineoplastic therapy.Objectives: To de ... Full text Link to item Cite

Impact of the Percepta Genomic Classifier on Clinical Management Decisions in a Multicenter Prospective Study.

Journal Article Chest · January 2021 BACKGROUND: The Percepta genomic classifier has been clinically validated as a complement to bronchoscopy for lung nodule evaluation. RESEARCH QUESTION: The goal of this study was to examine the impact on clinical management decisions of the Percepta resul ... Full text Link to item Cite

Variable Learning Curve of Basic Rigid Bronchoscopy in Trainees.

Journal Article Respiration; international review of thoracic diseases · January 2021 BackgroundDespite increased use of rigid bronchoscopy (RB) for therapeutic indications and recommendations from professional societies to use performance-based competency, an assessment tool has not been utilized to measure the competency of train ... Full text Cite

Cognitive Load in Electromagnetic Navigational and Robotic Bronchoscopy for Pulmonary Nodules.

Conference ATS Sch · December 23, 2020 Background: Electromagnetic navigational bronchoscopy (ENB) and robotic-assisted bronchoscopy (RB) require a high degree of decision-making and psychomotor skill. Cognitive load theory is the overall effort expended by individuals in response to a task and ... Full text Link to item Cite

Operator Perception of a Single-Use Flexible Bronchoscope: Comparison With Current Standard Bronchoscopes.

Journal Article Respir Care · November 2020 BACKGROUND: Single-use flexible bronchoscopes have gained popularity in recent years for various advantages over the traditional reusable bronchoscope. There are several commercially available disposable bronchoscopes; however, all have limitations compare ... Full text Link to item Cite

Management of Indwelling Tunneled Pleural Catheters: A Modified Delphi Consensus Statement.

Journal Article Chest · November 2020 BACKGROUND: The management of recurrent pleural effusions remains a challenging issue for clinicians. Advances in management have led to increased use of indwelling tunneled pleural catheters (IPC) because of their effectiveness and ease of outpatient plac ... Full text Link to item Cite

Endobronchial coils for emphysema: Dual mechanism of action on lobar residual volume reduction.

Journal Article Respirology · November 2020 BACKGROUND AND OBJECTIVE: The RENEW trial demonstrated that bronchoscopic lung volume reduction using endobronchial coils improves quality of life, pulmonary function and exercise performance. In this post hoc analysis of RENEW, we examine the mechanism of ... Full text Link to item Cite

AABIP Evidence-informed Guidelines and Expert Panel Report for the Management of Indwelling Pleural Catheters.

Journal Article J Bronchology Interv Pulmonol · October 2020 BACKGROUND: While the efficacy of Indwelling pleural catheters for palliation of malignant pleural effusions is supported by relatively robust evidence, there is less clarity surrounding the postinsertion management. METHODS: The Trustworthy Consensus-Base ... Full text Link to item Cite

The Use of Bronchoscopy During the Coronavirus Disease 2019 Pandemic: CHEST/AABIP Guideline and Expert Panel Report.

Journal Article Chest · September 2020 BACKGROUND: The coronavirus disease 2019 (COVID-19) has swept the globe and is causing significant morbidity and mortality. Given that the virus is transmitted via droplets, open airway procedures such as bronchoscopy pose a significant risk to health-care ... Full text Link to item Cite

Interventional Bronchoscopy.

Journal Article Am J Respir Crit Care Med · July 1, 2020 For over 150 years, bronchoscopy, especially flexible bronchoscopy, has been a mainstay for airway inspection, the diagnosis of airway lesions, therapeutic aspiration of airway secretions, and transbronchial biopsy to diagnose parenchymal lung disorders. I ... Full text Link to item Cite

Effect of Zephyr Endobronchial Valves on Dyspnea, Activity Levels, and Quality of Life at One Year. Results from a Randomized Clinical Trial.

Journal Article Ann Am Thorac Soc · July 2020 Rationale: Bronchoscopic lung volume reduction with Zephyr Valves improves lung function, exercise tolerance, and quality of life of patients with hyperinflated emphysema and little to no collateral ventilation.Objectives:Post hoc analysis of patient-repor ... Full text Link to item Cite

Cone beam navigation bronchoscopy: the next frontier.

Journal Article J Thorac Dis · June 2020 Navigation bronchoscopy has reached a new horizon in its evolution. Combining with real-time imaging modalities, such as cone-beam computed tomography (CBCT) and augmented fluoroscopy (AF), navigation success can finally be confirmed with high degree of ac ... Full text Link to item Cite

Collection and Handling of Thoracic Small Biopsy and Cytology Specimens for Ancillary Studies: Guideline From the College of American Pathologists in Collaboration With the American College of Chest Physicians, Association for Molecular Pathology, American Society of Cytopathology, American Thoracic Society, Pulmonary Pathology Society, Papanicolaou Society of Cytopathology, Society of Interventional Radiology, and Society of Thoracic Radiology.

Journal Article Archives of pathology & laboratory medicine · May 2020 Context.—The need for appropriate specimen use for ancillary testing has become more commonplace in the practice of pathology. This, coupled with improvements in technology, often provides less invasive methods of testing, but presents new challen ... Full text Cite

Transbronchial Cryobiopsy for the Diagnosis of Interstitial Lung Diseases: CHEST Guideline and Expert Panel Report.

Journal Article Chest · April 2020 BACKGROUND: Transbronchial cryobiopsy (TBC) is increasingly recognized as a potential alternative to surgical lung biopsy (SLB) for the diagnosis of interstitial lung disease (ILD). The goal of this analysis was to examine the literature on TBC as it relat ... Full text Link to item Cite

A Prospective Randomized Comparative Study of Three Guided Bronchoscopic Approaches for Investigating Pulmonary Nodules: The PRECISION-1 Study.

Journal Article Chest · March 2020 BACKGROUND: The capability of bronchoscopy in the diagnosis of peripheral pulmonary nodules (PPNs) remains limited. Despite decades of effort, evidence suggests that the diagnostic accuracy for electromagnetic navigational bronchoscopy (EMN) and radial end ... Full text Link to item Cite

State of the Art: Interventional Pulmonology.

Journal Article Chest · March 2020 Interventional pulmonology (IP) has evolved over the past decade from an obscure subspecialty in pulmonary medicine to a recognized discipline offering advanced consultative and procedural services to patients with thoracic malignancy, anatomic airway dise ... Full text Link to item Cite

Optimal diagnosis and treatment of malignant disease: Challenging the guidelines

Journal Article ERS Monograph · January 1, 2020 The evidence base for the diagnosis and management of malignant pleural disease has strengthened significantly in the last decade. In this chapter, we summarise the new research that will be included in the next iteration of international guidelines. In di ... Full text Cite

Yield Evaluation of Biopsied Pulmonary Nodules in Fluoroscopy Integrated Bronchoscopic Navigation System

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · 2020 Cite

Clinical and radiographic predictors of successful therapeutic bronchoscopy for the relief of malignant central airway obstruction.

Journal Article BMC Pulm Med · November 21, 2019 BACKGROUND: Malignant central airway obstruction (CAO) occurs in approximately 20-30% of patients with lung cancer and is associated with debilitating symptoms and poor prognosis. Multimodality therapeutic bronchoscopy can relieve malignant CAO, though car ... Full text Open Access Link to item Cite

Prospective Multicentered Safety and Feasibility Pilot for Endobronchial Intratumoral Chemotherapy.

Journal Article Chest · September 2019 BACKGROUND: Malignant airway obstruction (MAO) occurs in 30% of patients with advanced-stage lung cancer, leading to debilitating dyspnea, cough, and hemoptysis. Other than recanalization of the airways, these patients lack long-lasting palliative therapy. ... Full text Link to item Cite

Basic Bronchoscopy: Technology, Techniques, and Professional Fees.

Journal Article Chest · May 2019 Flexible bronchoscopy has evolved over the last few decades, allowing chest physicians to use advanced high-definition scopes to inspect the airways and perform various sampling techniques. Although the techniques of basic bronchoscopic sampling have not c ... Full text Link to item Cite

Predictors of Response to Endobronchial Coil Therapy in Patients With Advanced Emphysema.

Journal Article Chest · May 2019 BACKGROUND: The Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) trial reported improvements in quality of life, pulmonary function, and exercise performance following endobronchial coil treatment. OBJECTIVES: The purpose of this pos ... Full text Link to item Cite

Yield of Malignant Pleural Effusion for Detection of Oncogenic Driver Mutations in Lung Adenocarcinoma.

Journal Article J Bronchology Interv Pulmonol · April 2019 BACKGROUND: Pleural fluid can be used to assess targetable mutations in patients with lung adenocarcinoma. The primary objective of this study was to assess the yield of pleural fluid cytology for targetable oncogenic mutations (EGFR, KRAS, BRAF, ALK, and ... Full text Link to item Cite

Management of Lung Transplant Bronchial Stenosis With Mitomycin C.

Journal Article J Bronchology Interv Pulmonol · April 2019 BACKGROUND: Bronchial stenosis is a significant source of morbidity among lung transplant recipients, with etiologies including infection and ischemia of the airways. Current management with balloon bronchoplasty and stents is imperfect and a subset of pat ... Full text Link to item Cite

Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions: One-Year Results of the Prospective, Multicenter NAVIGATE Study.

Journal Article J Thorac Oncol · March 2019 INTRODUCTION: Electromagnetic navigation bronchoscopy (ENB) is a minimally invasive technology that guides endoscopic tools to pulmonary lesions. ENB has been evaluated primarily in small, single-center studies; thus, the diagnostic yield in a generalizabl ... Full text Link to item Cite

Management of Immunotherapy-Related Toxicities, Version 1.2019.

Journal Article J Natl Compr Canc Netw · March 1, 2019 The aim of the NCCN Guidelines for Management of Immunotherapy-Related Toxicities is to provide guidance on the management of immune-related adverse events resulting from cancer immunotherapy. The NCCN Management of Immunotherapy-Related Toxicities Panel i ... Full text Link to item Cite

Indwelling Pleural Catheter versus Pleurodesis for Malignant Pleural Effusions. A Systematic Review and Meta-Analysis.

Journal Article Ann Am Thorac Soc · January 2019 RATIONALE: Several randomized trials have compared the efficacy of an indwelling pleural catheter (IPC) versus the more traditional chemical pleurodesis in the management of malignant pleural effusion (MPE). OBJECTIVES: As part of the American Thoracic Soc ... Full text Link to item Cite

Safety and Efficacy of Remimazolam Compared With Placebo and Midazolam for Moderate Sedation During Bronchoscopy.

Journal Article Chest · January 2019 BACKGROUND: While the complexity of flexible bronchoscopy has increased, standard options for moderate sedation medications have not changed in three decades. There is a need to improve moderate sedation while maintaining safety. Remimazolam was developed ... Full text Link to item Cite

Post Cardiac Surgery Pleural Effusions and Thoracentesis

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2019 Link to item Cite

A Multicenter Randomized Controlled Trial of Zephyr Endobronchial Valve Treatment in Heterogeneous Emphysema (LIBERATE).

Journal Article Am J Respir Crit Care Med · November 1, 2018 RATIONALE: This is the first multicenter randomized controlled trial to evaluate the effectiveness and safety of Zephyr Endobronchial Valve (EBV) in patients with little to no collateral ventilation out to 12 months. OBJECTIVES: To evaluate the effectivene ... Full text Link to item Cite

Management of Malignant Pleural Effusions. An Official ATS/STS/STR Clinical Practice Guideline.

Journal Article Am J Respir Crit Care Med · October 1, 2018 BACKGROUND: This Guideline, a collaborative effort from the American Thoracic Society, Society of Thoracic Surgeons, and Society of Thoracic Radiology, aims to provide evidence-based recommendations to guide contemporary management of patients with a malig ... Full text Link to item Cite

Study Design and Rationale: A Multicenter, Prospective Trial of Electromagnetic Bronchoscopic and Electromagnetic Transthoracic Navigational Approaches for the Biopsy of Peripheral Pulmonary Nodules (ALL IN ONE Trial).

Journal Article Contemp Clin Trials · August 2018 BACKGROUND: Pulmonary nodules are a common but difficult issue for physicians as most identified on imaging are benign but those identified early that are cancerous are potentially curable. Multiple diagnostic options are available, ranging from radiograph ... Full text Link to item Cite

Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in the Diagnosis of Breast Cancer Thoracic Metastases and Detection of Receptor Discordance.

Journal Article J Bronchology Interv Pulmonol · July 2018 BACKGROUND: Metastasis of breast cancer to mediastinal lymph nodes is common and biopsy of suspicious lesions can have important diagnostic, prognostic, and therapeutic implications, particularly with respect to tumor receptor status. Our aim was to show t ... Full text Link to item Cite

The Business of Bronchoscopy: How to Set up an Interventional Pulmonology Program.

Journal Article Clin Chest Med · March 2018 Interventional pulmonology has advanced rapidly over the last decade and continues to evolve with new medical advances and changes in the health care landscape. Establishing and developing a new interventional pulmonology program entails careful planning, ... Full text Link to item Cite

Navigational Bronchoscopy with Airo CT Confirmation - Biopsy of a Cystic Lesion

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2018 Link to item Cite

Mechanical Characteristics of 3D Printed Airway Stent

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2018 Link to item Cite

Safety and Feasibility of Erector Spinae Plane (ESP) Block in Diagnostic and Therapeutic Pleuroscopy: A Pilot Study

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2018 Link to item Cite

Transbronchial lung biopsy

Chapter · September 7, 2017 Full text Cite

Elective Venovenous Extracorporeal Membrane Oxygenation for Resection of Endotracheal Tumor: A Case Report.

Journal Article A A Case Rep · August 15, 2017 We present a case in which we electively used venovenous extracorporeal membrane oxygenation (VV-ECMO) to facilitate safe resection of a nearly obstructing airway tumor near the carina in a 37-year-old male. The patient was brought to the operating room an ... Full text Link to item Cite

Novel Magnetic Resonance Imaging for Assessment of Bronchial Stenosis in Lung Transplant Recipients.

Journal Article Am J Transplant · July 2017 Bronchial stenosis in lung transplant recipients is a common disorder that adversely affects clinical outcomes. It is evaluated by spirometry, CT scanning, and bronchoscopy with significant limitations. We hypothesize that MRI using both ultrashort echo ti ... Full text Link to item Cite

Interventional Pulmonology Fellowship Accreditation Standards: Executive Summary of the Multisociety Interventional Pulmonology Fellowship Accreditation Committee.

Journal Article Chest · May 2017 Interventional pulmonology (IP) is a rapidly evolving subspecialty of pulmonary medicine. In the last 10 years, formal IP fellowships have increased substantially in number from five to now > 30. The vast majority of IP fellowship trainees are selected thr ... Full text Link to item Cite

Randomized Trial of Pleural Fluid Drainage Frequency in Patients with Malignant Pleural Effusions. The ASAP Trial.

Journal Article Am J Respir Crit Care Med · April 15, 2017 RATIONALE: Patients with malignant pleural effusions have significant dyspnea and shortened life expectancy. Indwelling pleural catheters allow patients to drain pleural fluid at home and can lead to autopleurodesis. The optimal drainage frequency to achie ... Full text Link to item Cite

Electromagnetic navigation bronchoscopy to access lung lesions in 1,000 subjects: first results of the prospective, multicenter NAVIGATE study.

Journal Article BMC Pulm Med · April 11, 2017 BACKGROUND: Electromagnetic navigation bronchoscopy (ENB) is an image-guided, minimally invasive approach that uses a flexible catheter to access pulmonary lesions. METHODS: NAVIGATE is a prospective, multicenter study of the superDimension™ navigation sys ... Full text Link to item Cite

Comprehensive Genetic Mutation Analysis On Pleural Effusions Related To Lung Adenocarcinoma

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2017 Link to item Cite

Post-Approval Study For Bronchial Thermoplasty (bt): Results To 2 Years

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2017 Link to item Cite

Haemoptysis

Journal Article ERS Monograph · January 1, 2017 Haemoptysis is a common clinical entity encountered in pulmonology. Its presentation ranges from blood-streaked sputum to massive haemoptysis. Appropriate assessment and management of this potentially life-threatening entity can lead to improved clinical o ... Full text Cite

The Changing Role for Tracheostomy in Patients Requiring Mechanical Ventilation.

Journal Article Clin Chest Med · December 2016 Tracheostomy is performed in patients who require prolonged mechanical ventilation or have upper airway instability. Percutaneous tracheostomy with Ciaglia technique is commonly used and rivals the surgical approach. Percutaneous technique is associated wi ... Full text Link to item Cite

Response.

Journal Article Chest · July 2016 Full text Link to item Cite

Effect of Endobronchial Coils vs Usual Care on Exercise Tolerance in Patients With Severe Emphysema: The RENEW Randomized Clinical Trial.

Journal Article JAMA · May 24, 2016 IMPORTANCE: Preliminary clinical trials have demonstrated that endobronchial coils compress emphysematous lung tissue and may improve lung function, exercise tolerance, and symptoms in patients with emphysema and severe lung hyperinflation. OBJECTIVE: To d ... Full text Link to item Cite

Design of a prospective, multicenter, global, cohort study of electromagnetic navigation bronchoscopy.

Journal Article BMC Pulm Med · April 26, 2016 BACKGROUND: Electromagnetic navigation bronchoscopy (ENB) procedures allow physicians to access peripheral lung lesions beyond the reach of conventional bronchoscopy. However, published research is primarily limited to small, single-center studies using pr ... Full text Link to item Cite

Development of a Tool to Assess Basic Competency in the Performance of Rigid Bronchoscopy.

Journal Article Ann Am Thorac Soc · April 2016 RATIONALE: Rigid bronchoscopy is increasingly used by pulmonologists for the management of central airway disorders. However, an assessment tool to evaluate the competency of operators in the performance of this technique has not been developed. We created ... Full text Link to item Cite

Interventional Pulmonology: Marching Forward Together.

Journal Article J Bronchology Interv Pulmonol · April 2016 Full text Link to item Cite

Technical Aspects of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: CHEST Guideline and Expert Panel Report.

Journal Article Chest · March 2016 BACKGROUND: Endobronchial ultrasound (EBUS) was introduced in the last decade, enabling real-time guidance of transbronchial needle aspiration (TBNA) of mediastinal and hilar structures and parabronchial lung masses. The many publications produced about EB ... Full text Link to item Cite

Endogenous pneumoconiosis: Analytical scanning electron microscopic analysis of a case.

Journal Article Ultrastruct Pathol · 2016 Pneumoconiosis is often considered a disease of the lung initiated by exposure to dust or other airborne particles, resulting in injury to the lungs. The term "endogenous pneumoconiosis" has been used in the literature to describe the deposition of compoun ... Full text Link to item Cite

Role Of Mitomycin C Application In Lung Transplantation Related Airway Stenosis

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2016 Link to item Cite

A randomised trial of lung sealant versus medical therapy for advanced emphysema.

Journal Article Eur Respir J · September 2015 Uncontrolled pilot studies demonstrated promising results of endoscopic lung volume reduction using emphysematous lung sealant (ELS) in patients with advanced, upper lobe predominant emphysema. We aimed to evaluate the safety and efficacy of ELS in a rando ... Full text Link to item Cite

The Use of Indwelling Tunneled Pleural Catheters for Recurrent Pleural Effusions in Patients With Hematologic Malignancies: A Multicenter Study.

Journal Article Chest · September 2015 BACKGROUND: Malignant pleural effusion is a common complication of advanced malignancies. Indwelling tunneled pleural catheter (IPC) placement provides effective palliation but can be associated with complications, including infection. In particular, hemat ... Full text Link to item Cite

Adult Bronchoscopy Training: Current State and Suggestions for the Future: CHEST Expert Panel Report.

Journal Article Chest · August 2015 BACKGROUND: The determination of competency of trainees in programs performing bronchoscopy is quite variable. Some programs provide didactic lectures with hands-on supervision, other programs incorporate advanced simulation centers, whereas others have a ... Full text Link to item Cite

Complications Following Therapeutic Bronchoscopy for Malignant Central Airway Obstruction: Results of the AQuIRE Registry.

Journal Article Chest · August 2015 BACKGROUND: There are significant variations in how therapeutic bronchoscopy for malignant airway obstruction is performed. Relatively few studies have compared how these approaches affect the incidence of complications. METHODS: We used the American Colle ... Full text Link to item Cite

Therapeutic bronchoscopy for malignant central airway obstruction: success rates and impact on dyspnea and quality of life.

Journal Article Chest · May 2015 BACKGROUND: There is significant variation between physicians in terms of how they perform therapeutic bronchoscopy, but there are few data on whether these differences impact effectiveness. METHODS: This was a multicenter registry study of patients underg ... Full text Link to item Cite

Simulation for Skills-based Education in Pulmonary and Critical Care Medicine.

Journal Article Ann Am Thorac Soc · April 2015 The clinical practice of pulmonary and critical care medicine requires procedural competence in many technical domains, including vascular access, airway management, basic and advanced bronchoscopy, pleural procedures, and critical care ultrasonography. Si ... Full text Link to item Cite

Bringing comfort to endobronchial ultrasound bronchoscopy.

Journal Article Am J Respir Crit Care Med · April 1, 2015 Full text Link to item Cite

Bronchomediastinal fistula caused by endobronchial aspergilloma.

Journal Article Ann Am Thorac Soc · January 2015 RATIONALE: Endobronchial aspergilloma is a rare condition affecting immunocompromised patients. We present three cases resulting in airway fistulae. CASE PRESENTATIONS: A 68-year-old male with orthotopic heart transplantation presented with fatigue, cough, ... Full text Link to item Cite

Therapeutic bronchoscopy improves spirometry, quality of life, and survival in central airway obstruction.

Journal Article Respiration · 2015 BACKGROUND: Central airway obstruction (CAO) occurs in patients with primary or metastatic lung malignancy and nonmalignant pulmonary disorders and results in significant adverse effects on respiratory function and quality of life. OBJECTIVES: The objectiv ... Full text Link to item Cite

High Dose Brachytherapy For Bronchial Stenosis In Lung Transplant Recipients

Conference AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2015 Link to item Cite

Therapeutic Bronchoscopy

Chapter · January 1, 2015 Full text Cite

Ablative therapies for central airway obstruction.

Journal Article Semin Respir Crit Care Med · December 2014 Central airway obstruction (CAO) is seen in malignant and nonmalignant airway disorders and can lead to significant morbidity and mortality. Endobronchial ablative therapies are used in conjunction with mechanical debridement to achieve hemostasis and rest ... Full text Link to item Cite

The use of convex probe endobronchial ultrasound-guided transbronchial needle aspiration in a pediatric population: a multicenter study.

Journal Article Pediatr Pulmonol · August 2014 INTRODUCTION: The presence of intrathoracic lymphadenopathy and mediastinal masses in the pediatric population often presents a diagnostic challenge. With limited minimally invasive methodologies to obtain a diagnosis, invasive sampling via mediastinoscopy ... Full text Link to item Cite

Tumor acquisition for biomarker research in lung cancer.

Journal Article Cancer Invest · July 2014 The biopsy collection data from two lung cancer trials that required fresh tumor samples be obtained for microarray analysis were reviewed. In the trial for advanced disease, microarray data were obtained on 50 patient samples, giving an overall success ra ... Full text Link to item Cite

Ventilation and anesthetic approaches for rigid bronchoscopy.

Journal Article Ann Am Thorac Soc · May 2014 Due to growing interest in management of central airway obstruction, rigid bronchoscopy is undergoing a resurgence in popularity among pulmonologists. Performing rigid bronchoscopy requires use of deep sedation or general anesthesia to achieve adequate pat ... Full text Link to item Cite

Rebuttal from drs Wahidi and Ernst.

Journal Article Chest · March 1, 2014 Full text Link to item Cite

Learning experience of linear endobronchial ultrasound among pulmonary trainees.

Journal Article Chest · March 1, 2014 BACKGROUND: Linear endobronchial ultrasound (EBUS) allows real-time guidance of transbronchial needle aspiration of thoracic structures and has become an increasingly important diagnostic tool for chest physicians. Little has been published about the learn ... Full text Link to item Cite

Feasibility of using an epigenetic marker of risk for lung cancer, methylation of p16, to promote smoking cessation among US veterans.

Journal Article BMJ Open Respir Res · 2014 INTRODUCTION: Providing smokers feedback using epigenetic markers of lung cancer risk has yet to be tested as a strategy to motivate smoking cessation. Epigenetic modification of Rb-p16 (p16) due to tobacco exposure is associated with increased risk of dev ... Full text Open Access Link to item Cite

Hemorrhagic complications of thoracentesis and small-bore chest tube placement in patients taking clopidogrel.

Journal Article Ann Am Thorac Soc · January 2014 RATIONALE: Clopidogrel is a commonly used antiplatelet medication. The risk of local hemorrhage associated with use of this drug during routine thoracentesis or small-bore chest tube placement is not well established. OBJECTIVES: We conducted a prospective ... Full text Link to item Cite

Rebuttal from Drs Wahidi and Yasufuku.

Journal Article Chest · September 2013 Full text Link to item Cite

Endobronchial fiducial to guide stereotactic body radiotherapy.

Journal Article J Bronchology Interv Pulmonol · July 2013 Optimal treatment for unresectable central airway tumors is not well established. Stereotactic body radiation therapy has shown efficacy for both peripheral and central lung lesions. However, the treatment of central tumors has been limited because of asso ... Full text Link to item Cite

Symptom management in patients with lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.

Journal Article Chest · May 2013 BACKGROUND: Many patients with lung cancer will develop symptoms related to their disease process or the treatment they are receiving. These symptoms can be as debilitating as the disease progression itself. To many physicians these problems can be the mos ... Full text Link to item Cite

Establishing the diagnosis of lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.

Journal Article Chest · May 2013 BACKGROUND: Lung cancer is usually suspected in individuals who have an abnormal chest radiograph or have symptoms caused by either local or systemic effects of the tumor. The method of diagnosis of lung cancer depends on the type of lung cancer (small cel ... Full text Link to item Cite

Straightening out chest tubes: what size, what type, and when.

Journal Article Clin Chest Med · March 2013 Although chest tube placement is one of the most common procedures in managing patients with pleural disease, it is not clear what size and type of chest tube is indicated for various conditions. Chest tubes can be divided into small- (≤14 French [Fr]) and ... Full text Link to item Cite

Significance of and risk factors for the development of central airway stenosis after lung transplantation.

Journal Article Am J Transplant · February 2013 Central airways stenosis (CAS) after lung transplant is a poorly understood complication. Objectives of this study were to determine if CAS was associated with chronic rejection or worse survival after transplant as well as to identify factors associated w ... Full text Link to item Cite

Alendronate tracheobronchitis.

Journal Article Ann Am Thorac Soc · February 2013 Full text Link to item Cite

Simulation for endoscopy training

Chapter · January 1, 2013 Bronchoscopy is a common procedure, with an estimated 500,000 bronchoscopies performed annually in the United States. It is mainly performed by pulmonologists, but surgeons, anesthesiologists, and intensivists also perform this procedure for a variety of d ... Full text Cite

Latest advances in advanced diagnostic and therapeutic pulmonary procedures.

Journal Article Chest · December 2012 Over the past 15 years, patients with a myriad of pulmonary conditions have been diagnosed and treated with new technologies developed for the pulmonary community. Advanced diagnostic and therapeutic procedures once performed in an operating theater under ... Full text Link to item Cite

Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patients.

Journal Article Arch Pathol Lab Med · November 2012 CONTEXT: Familial idiopathic interstitial pneumonia (F-IIP) describes the unexplained occurrence of diffuse parenchymal lung disease in related individuals. Prevailing wisdom suggests that the histopathology of F-IIP is indistinguishable from that of idiop ... Full text Link to item Cite

Endobronchial injection of botulinum toxin for the reduction of bronchial hyperreactivity induced by methacholine inhalation in dogs.

Journal Article J Bronchology Interv Pulmonol · October 2012 BACKGROUND: Airway smooth muscle contraction causes bronchial constriction and is the main cause of bronchospasm in response to stimulants in asthma patients. In this pilot study, we tested the possibility of using a commercially available neurotoxin-botul ... Full text Link to item Cite

Association of gender with outcomes in critically ill patients.

Journal Article Crit Care · May 22, 2012 INTRODUCTION: The influence of gender on mortality and other outcomes of critically ill patients is not clear. Different studies have been performed in various settings and patient populations often yielding conflicting results. We wanted to assess the rel ... Full text Link to item Cite

Bronchial thermoplasty for severe asthma.

Journal Article Am J Respir Crit Care Med · April 1, 2012 Bronchial thermoplasty (BT) is a novel treatment of patients with severe asthma who continue to be symptomatic despite maximal medical treatment. It aims to reduce the smooth muscle mass in the airways by delivering controlled thermal energy to the airway ... Full text Link to item Cite

Flexible Bronchoscopy Training

Journal Article · January 5, 2012 Full text Cite

Response

Journal Article Chest · January 1, 2012 Full text Cite

Response

Journal Article Chest · January 1, 2012 Full text Cite

Endobronchial metastatic breast cancer with pagetoid histology mimicking bronchial pagetoid squamous cell carcinoma in situ.

Journal Article Hum Pathol · November 2011 We report a case of a 56-year-old woman with endobronchial breast cancer metastasis of unusual histology. The patient presented with persistent cough, and a lesion was noted in the left mainstem bronchus on bronchoscopic examination. Biopsy revealed extens ... Full text Link to item Cite

American College of Chest Physicians consensus statement on the use of topical anesthesia, analgesia, and sedation during flexible bronchoscopy in adult patients.

Journal Article Chest · November 2011 BACKGROUND: Optimal performance of bronchoscopy requires patient's comfort, physician's ease of execution, and minimal risk. There is currently a wide variation in the use of topical anesthesia, analgesia, and sedation during bronchoscopy. METHODS: A panel ... Full text Link to item Cite

Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomised, sham-controlled, multicentre trial.

Journal Article Lancet · September 10, 2011 BACKGROUND: Airway bypass is a bronchoscopic lung-volume reduction procedure for emphysema whereby transbronchial passages into the lung are created to release trapped air, supported with paclitaxel-coated stents to ease the mechanics of breathing. The aim ... Full text Link to item Cite

The use of electrocautery as the primary ablation modality for malignant and benign airway obstruction.

Journal Article J Thorac Oncol · September 2011 BACKGROUND: Laser has been the main ablative modality in the airways, but a growing experience with endobronchial electrocautery suggests a comparable efficacy and safety profile. OBJECTIVES: To evaluate the efficacy and safety of electrocautery as the pri ... Full text Link to item Cite

Fospropofol Disodium for Sedation in Elderly Patients Undergoing Flexible Bronchoscopy.

Journal Article J Bronchology Interv Pulmonol · January 2011 Featured Publication BACKGROUND: Fospropofol disodium is a water-soluble prodrug of propofol. A subset analysis was undertaken of elderly patients (≥65 y) undergoing flexible bronchoscopy, who were part of a larger multicenter, randomized, double-blind study. METHODS: Patients ... Full text Link to item Cite

Endobronchial metastatic breast cancer with pagetoid histology mimicking bronchial pagetoid squamous cell carcinoma in situ

Journal Article Human Pathology · January 1, 2011 We report a case of a 56-year-old woman with endobronchial breast cancer metastasis of unusual histology. The patient presented with persistent cough, and a lesion was noted in the left mainstem bronchus on bronchoscopic examination. Biopsy revealed extens ... Full text Cite

Accuracy of Bronchoscopic Implantation of an Anchored Beacon Transponder in a Cadaveric Human Lung Tumor Model

Conference International Journal of Radiation Oncology*Biology*Physics · November 2010 Full text Cite

Response

Journal Article Chest · September 1, 2010 Full text Cite

Training for endobronchial ultrasound: methods for proper training in new bronchoscopic techniques.

Journal Article Curr Opin Pulm Med · July 2010 Featured Publication PURPOSE OF REVIEW: The field of pulmonary medicine has experienced a rapid growth in innovative new technologies aimed at both diagnosis and treatment of airway, mediastinal and parenchymal disorders. Endobronchial ultrasound (EBUS) has emerged as an extre ... Full text Link to item Cite

A prospective multicenter study of competency metrics and educational interventions in the learning of bronchoscopy among new pulmonary fellows.

Journal Article Chest · May 2010 Featured Publication BACKGROUND: Learning medical procedures relies predominantly on the apprenticeship model, and competency is established based on the number of performed procedures. Our study aimed to establish bronchoscopy competency metrics based on performance and enhan ... Full text Link to item Cite

A multicenter pilot study of a bronchial valve for the treatment of severe emphysema.

Journal Article Respiration · 2010 Featured Publication BACKGROUND: Chronic obstructive pulmonary disease (COPD) affects millions of people and has limited treatment options. Surgical treatments for severe COPD with emphysema are effective for highly selected patients. A minimally invasive method for treating e ... Full text Link to item Cite

An approach to interventional pulmonary fellowship training.

Journal Article Chest · January 2010 Featured Publication Interventional pulmonology continues to be a specialty that is experiencing an evolution of new technologies, with an emphasis on multidisciplinary care. The diversity and application of these procedures in patients with more complex conditions is leading ... Full text Link to item Cite

Comparative effectiveness of low- and high-fidelity bronchoscopy simulation for training in conventional transbronchial needle aspiration and user preferences.

Journal Article Respiration · 2010 Featured Publication BACKGROUND: Conventional transbronchial needle aspiration (TBNA) can be learned using high-fidelity virtual-reality platforms and low-fidelity models comprised of molded silicone or excised animal airways. OBJECTIVES: The purpose of this study was to deter ... Full text Link to item Cite

Comparison of transbronchial lung biopsy yield between standard forceps and electrocautery hot forceps in swine.

Journal Article Respiration · 2010 Featured Publication BACKGROUND: Transbronchial lung biopsy (TBLB) is a commonly performed bronchoscopic procedure. Previous studies have suggested that larger biopsy forceps may improve diagnostic yield; however, the risk of bleeding associated with larger samples may be incr ... Full text Link to item Cite

The Hi-Lo-Fidelity Comparative TBNA Training Study: Educational Effectiveness And User Preferences

Journal Article AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE · January 1, 2010 Link to item Cite

ICU procedures of the critically ill.

Journal Article Respirology · November 2009 Featured Publication Intensive Care Unit (ICU) patients often require urgent, high-risk diagnostic and therapeutic procedures. However, they are particularly vulnerable to procedural complications due to the severity and instability of their illnesses. We discuss the complicat ... Full text Link to item Cite

Diagnosis and outcome of early pleural space infection following lung transplantation.

Journal Article Chest · February 2009 Featured Publication BACKGROUND: Despite the frequent occurrence of pleural effusions in lung transplant recipients, little is known about early posttransplant pleural space infections. We sought to determine the predictors and clinical significance of pleural infection in thi ... Full text Link to item Cite

Transbronchial lung biopsy

Chapter · January 1, 2009 INTRODUCTION Transbronchial lung biopsy (TBB) is a safe and effective tool useful for the diagnosis of a wide variety of diffuse and focal pulmonary diseases. TBB is regularly performed by 69% of practicing physicians documented in a survey of 1,800 North ... Full text Cite

A phase 3, randomized, double-blind study to assess the efficacy and safety of fospropofol disodium injection for moderate sedation in patients undergoing flexible bronchoscopy.

Journal Article Chest · January 2009 Featured Publication BACKGROUND: Fospropofol disodium is a water-soluble prodrug of propofol with unique pharmacokinetic/pharmacodynamic properties. This randomized, double-blind, multicenter study evaluated the use of fospropofol in patients undergoing flexible bronchoscopy. ... Full text Link to item Cite

Adult tracheoesophageal fistula: A multidisciplinary approach

Journal Article Clinical Pulmonary Medicine · May 1, 2008 Fistulization between the respiratory and gastrointestinal tracts is an uncommon problem that results from a spectrum of disease processes. Tracheoesophageal fistula (TEF) formation can be either acquired or congenital; the congenital variety is a rare pro ... Full text Cite

Ultrasound: the pulmonologist's new best friend.

Journal Article Chest · April 2008 Featured Publication Full text Link to item Cite

Broncholith removal using cryotherapy during flexible bronchoscopy: a case report.

Journal Article Chest · November 2007 Featured Publication Pulmonary broncholithiasis can cause a management dilemma depending on its location and the possible involvement of vascular structures. Many patients undergo rigid bronchoscopy or surgical interventions for the removal of broncholiths. In this case report ... Full text Link to item Cite

Evidence for the treatment of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition).

Journal Article Chest · September 2007 Featured Publication BACKGROUND: The solitary pulmonary nodule (SPN) is a frequent incidental finding that may represent primary lung cancer or other malignant or benign lesions. The optimal management of the SPN remains unclear. METHODS: We conducted a systematic literature r ... Full text Link to item Cite

State of the art: interventional pulmonology.

Journal Article Chest · January 2007 Featured Publication Interventional pulmonology (IP) provides comprehensive care to patients with structural airway disorders and pleural diseases. A growing armamentarium of diagnostic and therapeutic tools has expanded the interventional pulmonologist's ability to care for p ... Full text Link to item Cite

Pulmonary alveolar proteinosis diagnosed in pregnancy and managed with whole-lung lavage

Journal Article Journal of Bronchology · October 1, 2006 A 29-year-old woman presented with dyspnea, fatigue, and chills during the first trimester of pregnancy. She did not respond to empiric antibiotic therapy for bronchitis and was subsequently hospitalized with worsening respiratory symptoms and hypoxemia. D ... Full text Cite

Effect of routine clopidogrel use on bleeding complications after transbronchial biopsy in humans.

Journal Article Chest · March 2006 STUDY OBJECTIVES: Clopidogrel is often prescribed for primary or secondary prevention of cardiovascular disease and has been associated with unwanted bleeding events. After having shown that transbronchial biopsy can safely be performed in pigs receiving c ... Full text Link to item Cite

Clinical and pathologic features of familial interstitial pneumonia.

Journal Article Am J Respir Crit Care Med · November 1, 2005 RATIONALE: Several lines of evidence suggest that genetic factors and environmental exposures play a role in the development of pulmonary fibrosis. OBJECTIVES: We evaluated families with 2 or more cases of idiopathic interstitial pneumonia among first-degr ... Full text Link to item Cite

Endoscopic removal of metallic airway stents.

Journal Article Chest · June 2005 BACKGROUND: Complications of metallic airway stents include granulation tissue formation, fracture of struts, migration, and mucous plugging. When these complications result in airway injury or obstruction, it may become necessary to remove the stent. Ther ... Full text Link to item Cite

Effect of clopidogrel with and without aspirin on bleeding following transbronchial lung biopsy.

Journal Article Chest · March 2005 Featured Publication BACKGROUND: Clopidogrel, a potent inhibitor of platelet aggregation, is being commonly prescribed in the elderly population due to its benefits in patients with atherosclerotic diseases. It is currently unknown whether clopidogrel increases the risk of ble ... Full text Link to item Cite

Tracheostomy in mechanically ventilated patients: unanswered questions.

Journal Article Crit Care Med · February 2005 Featured Publication Full text Link to item Cite

Ultrasound Guidance for Central Venous Catheterization

Chapter · January 1, 2005 The central venous catheter (CVC) is a valuable tool in the care of patients in both inpatient and outpatient settings. It facilitates the administration of fluids or medications in patients with difficult peripheral access and provides timely therapies to ... Full text Cite

Role of the interventional pulmonologist in the intensive care unit.

Journal Article J Intensive Care Med · 2005 Featured Publication Interventional pulmonology is a new field within the pulmonary and critical care medicine specialty with a focus on invasive diagnostic and therapeutic modalities in airway and pleural disorders. The interventional pulmonologist is highly qualified to take ... Full text Link to item Cite

Contraindications and safety of transbronchial lung biopsy via flexible bronchoscopy. A survey of pulmonologists and review of the literature.

Journal Article Respiration · 2005 Featured Publication BACKGROUND: Transbronchial lung biopsy (TBLB) via flexible bronchoscopy is a common procedure performed by pulmonologists. Limited scientific data exist concerning the risk of this procedure in patients with conditions that may adversely affect the rate of ... Full text Link to item Cite

The role of bronchoscopy in the management of lung transplant recipients.

Journal Article Respir Care Clin N Am · December 2004 Featured Publication Bronchoscopy is an integral piece in the complex multidisciplinary approach to the care of lung transplant recipients. Although the use of surveillance bronchoscopies is controversial, bronchoscopy undoubtedly provides valuable information in patients with ... Full text Link to item Cite

A Simple Teaching Intervention Significantly Decreases Radiation Exposure during Transbronchial Biopsy

Journal Article Journal of Bronchology · April 1, 2004 The objective of this study was to assess the need for formal instruction on radiation safety and on a means to decrease radiation exposure during pulmonary procedures for healthcare workers and patients. Radiation safety is a major healthcare concern. No ... Full text Cite

The Montgomery T-tube tracheal stent.

Journal Article Clin Chest Med · September 2003 Featured Publication The Montgomery T-tube is a valuable tracheal stent that provides a functional airway while supporting the tracheal mucosa. It is used in benign and malignant tracheal diseases and provides symptomatic relief to the majority of the patients. T-tubes are sim ... Full text Link to item Cite

Deciding when to use percutaneous dilatational tracheostomy

Journal Article Journal of Respiratory Diseases · May 1, 2003 Percutaneous dilatational tracheostomy (PDT) is a safe, minimally invasive procedure that can be performed at bedside in the ICU. The indications for PDT are the same as for surgical tracheostomy and include prolonged intubation, assistance in weaning from ... Cite

Genetics of familial pulmonary fibrosis and other variants

Chapter · January 1, 2003 Idiopathic pulmonary fibros (IPF) is an incurable disease with a 5-year survival of 30–50% from the time of diagnosis (1). In recent years, there has been much progress made in understanding the cellular and molecular events leading to pulmonary fibrosis ( ... Cite

Multiple lung nodules in a woman with a history of melanoma.

Journal Article Respiration · 2003 A 61-year-old Caucasian female presented with a 6-week history of dry persistent cough. She had no shortness of breath, chest pain, fever, chills, or weight loss. She had been diagnosed with melanoma on the left thigh 6 months earlier. It was a spindle cel ... Full text Link to item Cite

Ultrasound guidance for medical thoracoscopy: a novel approach.

Journal Article Respiration · 2003 BACKGROUND: Commonly, a pneumothorax is induced before medical thoracoscopy to facilitate safe entry into the pleural space. OBJECTIVE: Evaluate the use of transthoracic ultrasound to locate a safe entry site for trocar placement during medical thoracoscop ... Full text Link to item Cite

Progression of idiopathic pulmonary fibrosis in native lungs after single lung transplantation.

Journal Article Chest · June 2002 This retrospective, single-center study was conducted to assess the response of native idiopathic pulmonary fibrosis (IPF) lungs to a potent cyclosporine-based immunosuppressive regimen in single-lung transplantation recipients. The study included IPF pati ... Full text Link to item Cite

Upper airway obstruction in a patient with epidermolysis bullosa acquisita

Journal Article Journal of Bronchology · January 1, 2002 Epidermolysis bullosa acquisita (EBA) is a rare, acquired autoimmune bullous disease characterized by the development of tense bullae spontaneously or due to minor trauma to the skin and mucosal surfaces. Mucosal involvement has been reported in the oral c ... Full text Cite

Familial pulmonary fibrosis in the USA.

Journal Article AMERICAN JOURNAL OF HUMAN GENETICS · October 1, 2001 Link to item Cite